iScience. 2025 May 15;28(6):112682. doi: 10.1016/j.isci.2025.112682. eCollection 2025 Jun 20.
ABSTRACT
Hypertension adversely affects glycolipid metabolism and vascular function in aging populations. This network meta-analysis evaluated 36 randomized trials (n = 2875) comparing traditional mind-body exercises (Tai Chi, Baduanjin, Daoyinyangshengshu) for metabolic and vascular improvements. Analyses revealed Tai Chi most effectively raised high-density lipoprotein (HDL) (standardized mean differences [SMD] = 0.88), while Daoyinyangshengshu optimally reduced fasting glucose (SMD = -1.21) and endothelin-1 (SMD = -1.82) while increasing nitric oxide (SMD = 1.41). Baduanjin best lowered low-density lipoprotein (LDL) (SMD = -0.95), with other exercises improving cholesterol and triglycerides. The findings demonstrate that specific mind-body practices differentially enhance cardiometabolic health, with Tai Chi and Daoyinyangshengshu showing particular promise for comprehensive benefits. These evidence-based results support incorporating traditional exercises into hypertension management protocols to address both metabolic and vascular dysfunction.
PMID:40510132 | PMC:PMC12159935 | DOI:10.1016/j.isci.2025.112682