Trace elements and vitamins status during pregnancy

Scritto il 01/06/2026
da Bénédicte Lelièvre

Ann Biol Clin (Paris). 2026 Apr 1;84(2):140-157. doi: 10.1684/abc.2026.2037.

ABSTRACT

Pregnancy is associated with physiological changes, particularly with regard to vitamins and trace elements. Crucial nutrients for optimal fetal development include vitamins B9 and B12, as well as minerals such as iron, zinc, copper, selenium, and iodine. Pregnant women with a history of bariatric surgery require special attention. Supplementation adjustment is mainly based on biological monitoring. Unfortunately, there are no validated reference values for the French population. The BIOMAT group of the SFBC aims to establish reference values for some of these parameters, in order to facilitate the detection of deficiencies and ensure appropriate monitoring of supplementation. The proposal for reference values is one of the objectives of the NUMASURG project. In the previous part of this article, the main physiological changes in organs, metabolism, hematology, and hormones during pregnancy were detailed. This second part of the article focuses on micronutrients, highlighting the potential risks associated with their deficiency during pregnancy.

PMID:42220277 | DOI:10.1684/abc.2026.2037