Front Oncol. 2026 May 11;16:1751548. doi: 10.3389/fonc.2026.1751548. eCollection 2026.
ABSTRACT
BACKGROUND: Pericardial tumors are rare cardiovascular disorders that often present with non-specific clinical symptoms and have traditionally required surgical intervention. Multimodal imaging is crucial for diagnosis, treatment planning, and prognostic evaluation.
CASE PRESENTATION: A 60-year-old woman was referred to our institution with a one-year history of progressive exertional chest tightness and dyspnea, which had significantly worsened over the preceding month. Multimodal imaging diagnosed a pericardial tumor dependent on a circumflex artery fistula for its blood supply. Transcatheter embolization of the fistula was consequently performed to devascularize the tumor. At the 1-year follow-up, surveillance imaging demonstrated significant tumor regression. During follow-up, the patient reported substantial resolution of symptoms, and her blood pressure remained well-controlled.
CONCLUSION: This case highlights the critical role of multimodal imaging in diagnosing and managing pericardial tumors. Furthermore, it demonstrates the therapeutic potential of transcatheter embolization for inoperable patients with pericardial paragangliomas.
PMID:42200026 | PMC:PMC13199112 | DOI:10.3389/fonc.2026.1751548