Neurology. 2026 Sep 22;107(6):e218441. doi: 10.1212/WNL.0000000000218441. Epub 2026 Sep 3.
ABSTRACT
The CREST-2 trial demonstrated that carotid artery stenting combined with intensive medical management (IMM) significantly reduces stroke risk in patients with high-grade asymptomatic carotid stenosis compared with IMM alone. Careful patient selection and operator skill are critical factors for procedural success and can provide real-world validation of stenting as an important adjunct to IMM for stroke prevention. Continued advances in medical management and stenting are expected. It remains vital to engage in shared decision-making when considering moving forward with stenting of asymptomatic carotid stenosis.
PMID:42691470 | DOI:10.1212/WNL.0000000000218441