Detection and Treatment of Unruptured Intracranial Aneurysms

Scritto il 10/03/2026
da Tatsuya Ishikawa

Brain Nerve. 2026 Mar;78(3):211-216. doi: 10.11477/mf.188160960780030211.

ABSTRACT

The detection of unruptured intracranial aneurysms (UIAs) through brain health screening is crucial for preventing subarachnoid hemorrhage. Magnetic resonance angiography (MRA) and three-dimensional computed tomographic angiography (3D-CTA) are effective diagnostic tools, and the use of 3T-MRI further enables the identification of small aneurysms. The UCAS Japan study reported an annual rupture rate of 0.95%, with aneurysm size, location, and morphology identified as key predictors of rupture risk. Treatment strategies have increasingly shifted from microsurgical clipping to endovascular therapy. Coil embolization remains a primary method, augmented by flow diverters and Woven EndoBridge (WEB) devices, which have broadened therapeutic options for complex or wide-neck aneurysms. Looking forward, artificial intelligence is expected to enhance rupture risk prediction and support individualized treatment planning. Therefore, brain health screening plays a vital role in identifying high-risk aneurysms and ensuring timely intervention, while avoiding unnecessary procedures in patients with low-risk lesions.

PMID:41804509 | DOI:10.11477/mf.188160960780030211