Association of Preoperative Serum Magnesium Levels and Acute Kidney Injury Following Thromboembolectomy in Acute Limb Ischemia

Eurasian J Med. 2026 May 5;58(3):1-5. doi: 10.5152/eurasianjmed.2026.251340.

ABSTRACT

BACKGROUND: A critical cardiovascular emergency is acute lower extremity ischemia (ALI). Acute kidney injury (AKI) after surgical embolectomy prolongs hospitalization and increases treatment costs. Low blood magnesium (Mg) levels were shown to be associated with renal dysfunction. In this study, the goal was to investigate the connection between AKI and preoperative Mg levels.

METHODS: Patients who underwent a surgical embolectomy for ALI between January 2016 and June 2024 were consecutively included in this retrospective study. After the exclusion criteria, patients were divided into 2 groups: those who developed AKI in the postoperative period (group 1) and those who did not (group 2).

RESULTS: The median ages of the 403 patients in group 2 and the 69 patients in group 1 were 64 (39-95 years) and 67 (35-89 years), respectively (P = .098). There was no statistical difference in terms of gender, prior cerebrovascular events, hypertension, diabetes mellitus, hyperlipidemia, rates of coronary artery disease, and peripheral arterial disease between the 2 groups. Glycated hemoglobin >9 (OR: 1.350, CI 95%: 1.110-1.984,- P = .028), high creatinine (OR: 2.945, CI 95%: 1.837-3.682, P < .001), and low Mg (OR: 0.695, CI 95%: 0.550- 0.869, P = .014) values were determined as independent predictors for AKI.

CONCLUSION: The current study demonstrates that preoperative low Mg levels may be a risk factor for AKI. Cite this article as: Engin M, As AK, Aydın U, Ata Y, Yavuz Ş. Association of preoperative serum magnesium levels and acute kidney injury following thromboembolectomy in acute limb ischemia. Eurasian J Med. 2026, 58(3), 1340, doi: 10.5152/ eurasianjmed.2026.251340.

PMID:42364189 | DOI:10.5152/eurasianjmed.2026.251340