Prognostic Significance of Upstroke Time per Cardiac Cycle in Coronary Artery Disease Patients With Normal Ankle-Brachial Index

Scritto il 11/06/2026
da Joh Akama

Circ Rep. 2026 Apr 15;8(6):1016-1018. doi: 10.1253/circrep.CR-26-0057. eCollection 2026 Jun 10.

ABSTRACT

BACKGROUND: Whether upstroke time (UT) predicts outcomes after percutaneous coronary intervention (PCI) in patients with normal ankle-brachial index (ABI) remains unclear.

METHODS AND RESULTS: In a registry, 713 patients with ABI 0.90-1.40 and no atrial fibrillation or known severe aortic stenosis were analyzed. UT was measured from brachial-ankle pulse volume recordings and classified as <180 or ≥180 ms. Prolonged UT was associated with high risk of unplanned revascularization for de novo lesions (adjusted hazard ratio 1.84, P=0.015).

CONCLUSIONS: UT prolongation indicates risk of de novo revascularization after PCI despite normal ABI.

PMID:42273318 | PMC:PMC13249491 | DOI:10.1253/circrep.CR-26-0057