Glob Cardiol Sci Pract. 2025 Dec 31;2025(6):e202559. doi: 10.21542/gcsp.2025.59. eCollection 2025 Dec 31.
ABSTRACT
Cytomegalovirus (CMV) infection has been implicated in endothelial dysfunction and atherogenesis, yet its role as a potential trigger for acute coronary syndrome (ACS) remains underrecognized. We present a case of a 32-year-old male with no prior medical history who developed non-ST elevation myocardial infarction (NSTEMI) and was subsequently found to have active CMV infection. The patient had no known history cardiovascular disease, though subsequent testing did reveal additional underlying risk factors. This case highlights the need to consider infectious etiologies, including CMV, as contributors to ACS in young, otherwise apparently healthy individuals. Understanding the interplay between viral infections and atherosclerotic disease may lead to improved risk stratification and management of patients presenting with ACS.
PMID:41978894 | PMC:PMC13070269 | DOI:10.21542/gcsp.2025.59