Acta Med Indones. 2026 Jul;58(3):386-392.
ABSTRACT
BACKGROUND: This study to validate the TIMI (Thrombolysis in Myocardial Infarction) core and also assess the validity of a modified TIMI score that includes three additional variables from primary percutaneous coronary intervention (PPCI) findings: left ventricular ejection fraction based on echocardiography post-PPCI, TIMI flow, and the number of lesions in a population of STEMI (ST-elevation myocardial infarction) patients who underwent PPCI at Cipto Mangunkusumo National Hospital, with a focus on predicting 30-day mortality. This is the first study to validate the TIMI score among STEMI patients who underwent PPCI at Cipto Mangunkusumo National Hospital. This study aimed to develop a modified TIMI score with enhanced ability to predict 30-day mortality among STEMI patients at Cipto Mangunkusumo National Hospital following PPCI.
RESULTS: Among 230 study subjects, the 30-day mortality rate for the patients post-PPCI was 10%. There was no significant association between ejection fraction based on echocardiography after PPCI, TIMI flow, or the number of lesions and 30-day mortality post-PPCI in the STEMI patients. The discrimination performance of the TIMI score in predicting 30-day mortality post-PPCI was AUC (Area Under the Curve) 0.901, with good calibration.
CONCLUSION: The performance of the TIMI score in terms of predicting 30-day mortality after PPCI in STEMI patients at Cipto Mangunkusumo National Hospital was excellent (AUC 0.901, 95% CI 0.849-0.952), with good calibration. TIMI score can predict the 30-day mortality rate among STEMI patients undergoing PPCI.
PMID:42845082