Compr Physiol. 2026 Apr;16(2):e70142. doi: 10.1002/cph4.70142.
ABSTRACT
This study highlights the previously unknown association of mosaic loss of the Y chromosome to impaired gas exchange and cardiac dysfunction, implicating mosaicism in immune-mediated, multi-organ decline and revealing a mechanistic basis for sex-biased vulnerability in COPD.
PMID:41930401 | DOI:10.1002/cph4.70142