Br J Pharmacol. 2026 Sep 25. doi: 10.1111/bph.70673. Online ahead of print.
ABSTRACT
Cardiovascular disease remains the leading cause of mortality globally, with a disproportionate burden in low- and middle-income countries. Melatonin, a hormone primarily produced by the pineal gland, exhibits notable antioxidant, anti-inflammatory and immunomodulatory properties that may confer cardiovascular benefits. Importantly, melatonin is also found in a wide range of dietary sources, raising the possibility that regular consumption of melatonin-rich foods could offer a low-cost, accessible strategy to support cardiovascular health. This review summarises knowledge on dietary melatonin and evaluates its potential to provide cardiovascular benefits.
PMID:42786941 | DOI:10.1111/bph.70673