Front Med (Lausanne). 2026 May 14;13:1829484. doi: 10.3389/fmed.2026.1829484. eCollection 2026.
ABSTRACT
BACKGROUND: Thoracic epidural analgesia is widely used for postoperative pain control and is generally considered safe. Rare but serious cardiovascular complications related to neuraxial sympathetic blockade have been reported.
CASE SUMMARY: We describe a postoperative intensive care unit patient who developed transient complete heart block during early ambulation while receiving a continuous thoracic epidural bupivacaine infusion. Telemetry demonstrated abrupt progression from sinus rhythm to high-grade atrioventricular block with ventricular standstill lasting approximately seven seconds, coinciding with hypotension and vagal symptoms. The episode resolved promptly with supportive care and interruption of the epidural infusion. No recurrent arrhythmias occurred after resumption of analgesia at a lower bupivacaine concentration.
CONCLUSION: This case highlights a rare but clinically significant complication of thoracic epidural bupivacaine infusion and underscores how local anesthetic effects, in combination with postoperative autonomic imbalance, may precipitate transient high-grade atrioventricular block.
PMID:42221122 | PMC:PMC13216194 | DOI:10.3389/fmed.2026.1829484