Obstet Gynecol Clin North Am. 2026 Sep;53(3):483-495. doi: 10.1016/j.ogc.2026.03.006. Epub 2026 May 13.
ABSTRACT
Midlife women, particularly during the menopausal transition, experience heightened vulnerability to sleep and circadian health disturbances. These disruptions are driven by hormonal changes, vasomotor symptoms, psychosocial stress, and aging-related factors. Poor sleep and circadian health are linked to an increased risk for cardiovascular disease, metabolic dysfunction, and cognitive performance decrements. Evidence-based interventions include hormone therapy, selective pharmacologic treatments, and nonpharmacologic approaches such as cognitive-behavioral therapy for insomnia, exercise, and mindfulness. Targeting both sleep and circadian domains may improve midlife women's health trajectories and support healthy aging.
PMID:42508874 | DOI:10.1016/j.ogc.2026.03.006