Curr Cardiol Rep. 2026 Feb 10;28(1):23. doi: 10.1007/s11886-025-02341-5.
ABSTRACT
PURPOSE OF REVIEW: As the obesity epidemic expands, the alarming acceleration of youth obesity represents a critical global health concern. This timely analysis explores the underlying biological and socio-environmental drivers of childhood obesity and evaluates its role in the growing incidence of cardiometabolic disease. Moreover, this review aims to identify the limitations of existing preventive health systems and examine intervention strategies designed to mitigate the escalating burdens imposed by pediatric obesity.
RECENT FINDINGS: Contemporary research seeks to characterize distinct youth obesity phenotypes and to distinguish measurable markers of adiposity in early life that are implicated in the progression of cardiometabolic dysfunction. Recognizing the deficiencies of modern exercise education curricula, studies evaluating the implementation of school-based health interventions have demonstrated significant improvements in body composition and metabolic profiles among children and adolescents. The long-term health and societal consequences posed by rising pediatric obesity constitute one of the greatest population health challenges of our time. Future research should prioritize uncovering additional genetic and epigenetic determinants of youth obesity and emphasize the equitable delivery of early, accessible, and sustainable school-based health promotion programs to reverse the global trajectory of obesity-related cardiometabolic disease.
PMID:41665704 | DOI:10.1007/s11886-025-02341-5