J Vis Exp. 2025 Nov 11;(225). doi: 10.3791/68682.
ABSTRACT
The paper aims to investigate the difference between the effect of enoxaparin alone and enoxaparin + lower limb circulation (LLC) in the prevention of deep vein thrombosis (DVT) after intertrochanteric fracture in older people and to provide a basis for clinical anticoagulant therapy. A total of 121 patients undergoing hip fracture (HF) surgery were divided into the enoxaparin group (71 patients) and the enoxaparin + LLC group (50 patients) to compare the baseline features, changes in D-Dimer Index (DDI), and the incidence and distribution of DVT between the two groups. There was no significant difference between the baseline data of the two groups (p > 0.05). There was no significant difference between the D-Dimer Levels (DDL) 1 day after surgery (p = 0.191). But 3 days after surgery, the D-Dimer level was significantly lower in the enoxaparin + LLC group than in the enoxaparin alone group (p < 0.05). The incidence of DVT in both groups was 35.21% and 36.00% and was not statistically different (p > 0.05). No significant difference was seen in the distribution of DVT types between the two groups (p > 0.05). However, there were two popliteal vein thromboses and one femoral vein thrombosis in the enoxaparin alone group. The enoxaparin + LLC group was better at reducing the D-Dimer level than the enoxaparin group, but there was no significant difference in the incidence and distribution type of DVT. It is recommended that the proper anticoagulation regimen be selected based on the patient's risk and that the postoperative D-Dimer monitoring be supported.
PMID:41325425 | DOI:10.3791/68682