Card Electrophysiol Clin. 2026 Dec;18(4):373-381. doi: 10.1016/j.ccep.2026.08.001.
ABSTRACT
Cardiac arrhythmias are associated with significant morbidity and mortality. Ventricular arrhythmogenesis is a dynamic interplay among an arrhythmogenic substrate, myocardial electrophysiologic properties, modifying factors, and triggering factors. Imbalances in the autonomic nervous system can lead to increased myocardial excitability, which is a major contributor to the pathophysiology of ventricular tachyarrhythmias. Myocardial excitability and ventricular arrhythmogenesis are modulated perioperatively through hemodynamic and physiologic management, anesthetic agents, or regional anesthetic and surgical techniques.
PMID:42963142 | DOI:10.1016/j.ccep.2026.08.001