Fto-mediated m6A demethylation of Lox drives atrial fibrosis and promotes atrial fibrillation in a murine model of hyperthyroidism

Europace. 2026 Mar 11:euag047. doi: 10.1093/europace/euag047. Online ahead of print.ABSTRACTBACKGROUND AND AIMS: Hyperthyroidism is a risk factor for atrial fibrillation (AF), and N6-methyladenosine (m6A) RNA methylation is crucial in cardiovascular regulation. However, the role of Fto-mediated m6A

H Han Gong

Long-term outcomes of patients implanted with a HeartMate 3 left ventricular assist device - a real-world, single center, observational study

ESC Heart Fail. 2026 Mar 11:xvag074. doi: 10.1093/eschf/xvag074. Online ahead of print.ABSTRACTAIMS: Left ventricular assist device (LVAD) therapy is an established treatment modality for patients with advanced heart failure with reduced ejection fraction (HFrEF). This study aimed to evaluate the lo

S Stijn Legtenberg

Intense Myocardial Uptake in a Patient with Fabry Disease - a new cause of false positive of Bone Scintigraphy mimicking cardiac amyloidosis

No abstractEur Heart J Cardiovasc Imaging. 2026 Mar 11:jeag072. doi: 10.1093/ehjci/jeag072. Online ahead of print.NO ABSTRACTPMID:41812220 | DOI:10.1093/ehjci/jeag072

C Claire Lucas

Optimised murine HFpEF models for translational pre-clinical studies

ESC Heart Fail. 2026 Mar 11:xvag072. doi: 10.1093/eschf/xvag072. Online ahead of print.ABSTRACTBACKGROUND AND AIMS: The most clinically representative murine models of HFpEF include a "2-hit" model combining nitrosative stress with metabolic perturbation and a "3-hit" model that also includes ageing

B Bailey McIntosh

Factors that impact in-hospital mortality due to STEMI versus NSTEMI in a first percutaneous coronary intervention: survival analysis

Arch Cardiol Mex. 2026;96(1):6-14. doi: 10.24875/ACM.24000164.ABSTRACTOBJECTIVE: Acute coronary syndrome is a potentially fatal disease if it is not intervened in a timely and appropriate manner. In Colombia in 2021, 51,988 deaths were recorded from this cause. The aim is to compare the clinical cha

M Miguel A Medina-Pabón

The HeartHealth Program: A Mixed Methods Study of a Community-Based Text Messaging Support Program for Patients With Cardiovascular Disease From 2020 to 2024

JMIR Cardio. 2026 Mar 11;10:e68896. doi: 10.2196/68896.ABSTRACTBACKGROUND: The HeartHealth program is a 6-month SMS text messaging-based support program offered to patients with a recent cardiovascular hospitalization or recent cardiovascular clinic visit in Western Sydney, Australia. Its customized

B Brodie Sheahen

Further mystification of SCN5A phenotypes: sodium channel blockade in individuals with loss-of-function sodium channel mutations dangerous or helpful?

No abstractEuropace. 2026 Mar 10;28(3):euag035. doi: 10.1093/europace/euag035.NO ABSTRACTPMID:41812136 | DOI:10.1093/europace/euag035

P Pieter G Postema

Clinical profile and prognosis of brugada syndrome SCN5A variant carriers with negative sodium channel blocker challenge

Europace. 2026 Mar 10;28(3):euag014. doi: 10.1093/europace/euag014.ABSTRACTAIMS: Loss-of-function (LOF) variants in SCN5A are associated with Brugada syndrome (BrS), progressive conduction slowing, and other arrhythmias. While the prognosis of SCN5A carriers with a positive sodium channel blocker ch

E Elodie Surget

Mortality score in chronic coronary syndrome: prediction model from the ISCHEMIA trial

Eur J Prev Cardiol. 2026 Mar 11:zwag116. doi: 10.1093/eurjpc/zwag116. Online ahead of print.ABSTRACTAIMS: Accurate stratification of mortality risk is essential for management of chronic coronary syndromes (CCS), but existing models focus primarily on short-term outcomes and acute settings. We aimed

E Eliano P Navarese

Single-Sided Dual-Functional MPC-HEMA Coating for DMEK Grafts to Achieve Fluid-Barrier/Anti-Fouling Performance and Native Matrix Preservation

ACS Appl Bio Mater. 2026 Mar 11. doi: 10.1021/acsabm.5c02385. Online ahead of print.ABSTRACTCorneal endothelial dysfunction is a leading cause of global blindness. Descemet's membrane endothelial keratoplasty (DMEK) is an advanced treatment, offering minimal invasiveness, rapid visual recovery, and

K Keyi Sun

Glutamine alleviates Staphylococcus aureus-induced mastitis by modulating macrophage polarisation

PLoS Pathog. 2026 Mar 11;22(3):e1014053. doi: 10.1371/journal.ppat.1014053. Online ahead of print.ABSTRACTMastitis, a major dairy industry challenge, is often caused by Staphylococcus aureus (S. aureus). Previous research linked gut microbiota disruption-induced by vancomycin in mice-to reduced micr

C Chunhui Feng

Left atrial strain reveals subclinical dysfunction in children after successful coarctation repair

PLoS One. 2026 Mar 11;21(3):e0344778. doi: 10.1371/journal.pone.0344778. eCollection 2026.ABSTRACTBACKGROUND: Although surgical repair of aortic coarctation (CoA) often restores hemodynamic integrity, subclinical myocardial dysfunction may persist long-term. Left atrial (LA) strain is a sensitive ma

T Thuy Thuc Minh Pham

Sodium glucose co-transporter inhibition as a strategy to stabilize the microvasculature in sickle cell disease

No abstractCardiovasc Res. 2026 Mar 11:cvag055. doi: 10.1093/cvr/cvag055. Online ahead of print.NO ABSTRACTPMID:41811761 | DOI:10.1093/cvr/cvag055

M Muhammad Shahzeb Khan

Pre-Procedural Time Spent in Atrial Fibrillation Using Intermittent ECG Monitoring Is Associated with Arrhythmia Recurrence After Ablation: The ISOLATION Cohort Study

Europace. 2026 Mar 11:euag044. doi: 10.1093/europace/euag044. Online ahead of print.ABSTRACTBACKGROUND: Atrial fibrillation (AF) is conventionally classified as paroxysmal or persistent. AF burden might better reflect response to rhythm-control interventions. This study evaluated the association bet

Z Z Habibi

Plasma Linoleic Acid Is Related to Lower Hepatic Steatosis Index and Higher Linoleate-Rich Cardiolipin in Adults with MAFLD

Am J Physiol Gastrointest Liver Physiol. 2026 Mar 11. doi: 10.1152/ajpgi.00344.2025. Online ahead of print.ABSTRACTLinoleic acid (LA: 18:2n-6) is a required nutrient that supports mitochondrial function as a component of the inner mitochondrial membrane, cardiolipin (CL). Tetralinoleoyl CL (LA4CL) s

A Ali Kalhori

Pelargonidin Inhibits Isoproterenol Induced Myocardial Fibrosis via Regulating Transforming Growth Factor-beta/Smad2/3 Signaling and Th2 Cytokines in Mice

Physiol Res. 2026 Mar 11;75(1):15-27.ABSTRACTPelargonidin, a natural anthocyanidin, is known for its anti-inflammatory, antioxidant, and cytoprotective properties, however its role in myocardial fibrosis remains unclear. This study explored the therapeutic potential of pelargonidin in a mouse model

J J Zhao

Interhospital transfers from the emergency department: a mixed-methods study on their characteristics and contextual factors influencing their quality

CJEM. 2026 Mar 11. doi: 10.1007/s43678-026-01128-z. Online ahead of print.ABSTRACTOBJECTIVES: Despite an increase in interhospital transfers and the safety risks they represent for patients, little is known about the quality of clinical practices in this field. This study aimed to characterize inter

F Fabian Severino

Left atrial anterior wall flutter: clinical, anatomical, and electrophysiological characteristics

No abstractJ Interv Card Electrophysiol. 2026 Mar 11. doi: 10.1007/s10840-026-02285-y. Online ahead of print.NO ABSTRACTPMID:41811614 | DOI:10.1007/s10840-026-02285-y

J José Alderete

Heart failure evidence update 2026

No abstractHeart Fail Rev. 2026 Mar 11;31(1):34. doi: 10.1007/s10741-026-10609-3.NO ABSTRACTPMID:41811612 | DOI:10.1007/s10741-026-10609-3

S Sotiria Liori

Past, Present and Future of Regenerative Gene Therapy for Ischemic Heart Failure

J Cardiovasc Transl Res. 2026 Mar 11;19(1):40. doi: 10.1007/s12265-025-10731-x.ABSTRACTDespite advances in heart failure management, current therapies largely focus on symptom relief and slowing disease progression, without reversing or preventing the underlying condition. As cardiovascular diseases

L Laura Florit Gonzalez

Molecular imaging of lymphatic organs provides prognostic value after acute myocardial infarction

Eur J Nucl Med Mol Imaging. 2026 Mar 11. doi: 10.1007/s00259-026-07809-2. Online ahead of print.ABSTRACTINTRODUCTION: Acute myocardial infarction (AMI) triggers local inflammation in the injured myocardium, followed by a systemic inflammatory response of lymphatic organs. This prospective trial (NCT

T Theresa Reiter

Long-Term Outcomes of Left Bundle-Branch Pacing vs Biventricular Pacing in Heart Failure: The HeartSync-LBBP Randomized Clinical Trial

JAMA Cardiol. 2026 Mar 11. doi: 10.1001/jamacardio.2026.0083. Online ahead of print.ABSTRACTIMPORTANCE: Left bundle-branch pacing (LBBP) has been proposed as an alternative to biventricular pacing (BiVP) for patients with heart failure with left bundle-branch block (LBBB). However, robust clinical e

X Xueying Chen

Acute HeartMate3 Malfunction Requiring Exchange Due to Intrapump Obstruction: Inflow Cannula Obstruction Can Cause HM3 Failure

ASAIO J. 2026 Mar 11. doi: 10.1097/MAT.0000000000002690. Online ahead of print.ABSTRACTHeartMate III (HM3) pump failure due to intrapump obstruction from biodebris or thrombosis is an uncommon but life-threatening condition. Here, we describe a case of HM3 failure from biodebris occluding the inflow

D Divyam Goel

Conduction System vs Biventricular Pacing in Heart Failure: The PhysioSync-HF Randomized Clinical Trial

JAMA Cardiol. 2026 Mar 11. doi: 10.1001/jamacardio.2026.0101. Online ahead of print.ABSTRACTIMPORTANCE: Conduction system pacing (CSP) is a promising and potentially cost-effective alternative to biventricular pacing (BiVP) in patients with heart failure with reduced ejection fraction (HFrEF) and le

A André Zimerman