Clin Nutr ESPEN. 2025 May 28:S2405-4577(25)00339-0. doi: 10.1016/j.clnesp.2025.05.042. Online ahead of print.
ABSTRACT
BACKGROUND: Prolonged postoperative inactivity after cardiovascular surgery is associated with a decline in functional capacity. Early cardiac rehabilitation (CR) is vital for older patients with frailty and sarcopenia. The phase angle (PhA), a marker of skeletal muscle quality measured by bioelectrical impedance analysis (BIA), is associated with physical performance and long-term outcomes; however, its relationship with postoperative rehabilitation progress remains unclear.
OBJECTIVES: This study investigated the relationship between preoperative PhA and 100-m walking acquisition in older patients.
METHODS: A retrospective, observational, single-center study was conducted on patients aged ≥ 65 years who underwent elective cardiovascular surgery. The primary outcome was days from surgery to 100-m walking acquisition. Kaplan-Meier survival curves and Cox proportional hazards regression analyses were used to evaluate the relationship between PhA and outcomes.
RESULTS: Among 97 patients, the median PhA was 4.9°, dividing them into Low-PhA (< 4.9°, n = 48) and High-PhA (PhA≥ 4.9°, n = 49) groups. The Low-PhA group required significantly more days for 100-m walking acquisition and had lower 100-m walking acquisition rates (log-rank P < 0.001). Cox regression analysis identified preoperative PhA as an independent factor associated with 100-m walking acquisition (HR, 1.519; 95% CI: 1.078-2.140, P = 0.017).
CONCLUSIONS: A lower preoperative PhA is associated with delayed 100-m walking acquisition in older patients undergoing cardiovascular surgery.
PMID:40447227 | DOI:10.1016/j.clnesp.2025.05.042