Diagnostic Approach to Cardiac Sarcoidosis

Circulation. 2026 Jul 21;154(3):288-295. doi: 10.1161/CIRCULATIONAHA.126.079275. Epub 2026 Jul 20.ABSTRACTCardiac sarcoidosis is a granulomatous myocarditis, classified by some authorities as an infiltrative cardiomyopathy and by others as an inflammatory cardiomyopathy, that carries an elevated ris

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Does Characterization of Phenotypic Heterogeneity Provide Mechanistic Insights or Influence the Response to Treatment? Experience in Positive and Neutral Trials in Patients With Heart Failure and a Preserved Ejection Fraction

Circulation. 2026 Jul 21;154(3):271-287. doi: 10.1161/CIRCULATIONAHA.126.079235. Epub 2026 Jul 20.ABSTRACTAt a time when there was no unifying hypothesis and no broadly effective treatments for heart failure with a preserved ejection fraction (HFpEF), it was proposed that HFpEF represented a multitu

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