A deep cardiac motion field analysis approach via global 2nd-order kinematic graph modeling

Comput Med Imaging Graph. 2026 Apr 8;131:102763. doi: 10.1016/j.compmedimag.2026.102763. Online ahead of print.ABSTRACTCardiac motion analysis plays a vital role in the diagnosis and treatment of cardiovascular diseases. Existing methods can estimate displacement fields and model spatio-temporal pat

R Ruonan Xie

Areas of patent innovation regarding diabetic foot ulcers: technological prospecting

Invest Educ Enferm. 2026 Mar;44(1). doi: 10.17533/udea.iee.v44n1e08.ABSTRACTOBJECTIVE: To identify areas of innovation in internationally registered patents focused on diabetic foot ulcers.METHODS: This is a quantitative technological prospecting of international patents, from 2020 to 2024, in the W

V Vanessa Faria de Freitas

Outcomes After Minor Ischemic Stroke in Older Patients Treated With IV Thrombolysis vs Standard of Care in the TEMPO-2 Trial

Neurology. 2026 May 12;106(9):e214925. doi: 10.1212/WNL.0000000000214925. Epub 2026 Apr 14.ABSTRACTBACKGROUND AND OBJECTIVES: There are few high-quality data on thrombolysis outcomes in the oldest patients, especially for minor stroke. We examined safety and efficacy outcomes of thrombolysis in pati

A Aravind Ganesh

Adverse Muscle Composition is Associated with All-Cause Mortality in CKD: A UK Biobank Imaging Study

Clin J Am Soc Nephrol. 2026 Apr 14. doi: 10.2215/CJN.0000001049. Online ahead of print.ABSTRACTBACKGROUND: Adverse muscle composition (AMC), defined by low muscle volume and increased muscle fat infiltration, has been associated with comorbidity and poor function in chronic kidney disease (CKD), and

A Ainhoa Indurain

InflammAging and Human Diversity: Expanding Horizons in Age-Related Chronic Disease

Aging Dis. 2026 Apr 7. doi: 10.14336/AD.2026.0077. Online ahead of print.ABSTRACTInflammAging (IA) is a sterile, low-grade systemic inflammation characterizing human aging. This chronic inflammatory state, combining "inflammation" and "aging", drives the aging trajectory and associated pathology eve

J José M Izquierdo

Development of Virtual Mental Health Stepped Care Service for a Heart Failure Remote Management Program: Qualitative Descriptive Study

JMIR Form Res. 2026 Apr 14;10:e82139. doi: 10.2196/82139.ABSTRACTBACKGROUND: Depression is highly prevalent yet undertreated among people living with heart failure, indicating barriers to mental health services. Although various digital mental health interventions have been developed to detect, trea

A Amika Shah

Effect of a Comprehensive Mobile-Based Respiratory Training Program on Respiratory Function in Survivors of Acute Stroke: Randomized Controlled Trial

JMIR Mhealth Uhealth. 2026 Apr 14;14:e78637. doi: 10.2196/78637.ABSTRACTBACKGROUND: Respiratory dysfunction frequently occurs during the acute phase of stroke and is associated with reduced ventilatory capacity, respiratory muscle weakness, and increased pulmonary complications. However, delivering

Z Zong-Ke Ma

Empowering Birth Workers to Address Maternal Hypertension: Evaluation of a Community-Based Training in Wisconsin

WMJ. 2026;125(1):225-227.ABSTRACTBACKGROUND: Hypertensive disorders of pregnancy are a leading cause of maternal morbidity, especially among Black, Indigenous, and rural birthing individuals.METHODS: A multidisciplinary team developed and evaluated a community-based training for birth workers to enh

K Kristine Alaniz

Trem2 exacerbates ischemic brain injury through Gpnmb in a photothrombotic stroke model

Proc Natl Acad Sci U S A. 2026 Apr 21;123(16):e2523148123. doi: 10.1073/pnas.2523148123. Epub 2026 Apr 14.ABSTRACTIschemic stroke is a major public health challenge, with microglia-mediated neuroinflammation exerting both protective and detrimental effects on neuronal survival. The Triggering recept

X Xuezhen Chen

Multiomics Analysis Reveals the Protective Effect of a Novel Bioactive Peptide (BP1) in Cardiomyopathy Using a Zebrafish Model

J Proteome Res. 2026 Apr 14. doi: 10.1021/acs.jproteome.5c00809. Online ahead of print.ABSTRACTMedicinal plants have been used in traditional healthcare systems and drug discovery since ancient times, owing to their storage of natural products, including bioactive metabolites and peptides. Bioactive

S Shweta Thakur

Bivalent RSV Prefusion F Protein-Based Vaccine Effectiveness in Individuals With and Without Diabetes: A Prespecified Analysis of the DAN-RSV Trial

No abstractDiabetes Care. 2026 Apr 14:dca260020. doi: 10.2337/dca26-0020. Online ahead of print.NO ABSTRACTPMID:41980043 | DOI:10.2337/dca26-0020

M Manan Pareek

Stretching-Positioned Extracorporeal Shock Wave Therapy Yields Superior Short-Term Efficacy for Post-Stroke Upper-Limb Spasticity: A Retrospective Comparative Study

Med Sci Monit. 2026 Apr 14;32:e951444. doi: 10.12659/MSM.951444.ABSTRACTBACKGROUND Extracorporeal shock wave therapy (ESWT) reduces post-stroke spasticity, but the optimal muscle position during application is unclear. We hypothesized that ESWT applied under muscle stretch would yield superior anti-

J Jing Ouyang

Hypotension Prediction Index-Guided Hemodynamic Management on Postoperative Organ Outcome: A Systematic Review and Meta-Analysis of Randomized Clinical Trials

A A Pract. 2026 Apr 14;20(4):e02180. doi: 10.1213/XAA.0000000000002180. eCollection 2026 Apr 1.ABSTRACTIntraoperative hypotension (IOH) is a frequent occurrence during noncardiac surgery. Hypotensive episodes can compromise tissue perfusion, and cumulative exposure has been associated with adverse o

S Shi Shu Wang

Cardiovascular Outcomes in Diabetic Patients Treated with SGLT2i and GLP1-RA: A Systematic Review and Meta-Analysis

Cardiology. 2026 Apr 14:1-31. doi: 10.1159/000551686. Online ahead of print.ABSTRACTIntroduction Type 2 diabetes mellitus (T2DM) represents a significant public health issue due to its high prevalence and associated complications, particularly the cardiovascular and renal impairments that characteri

G Gaetano Marino

What effect does spiritual wellbeing have on parents of a baby with incurable heart disease? A qualitative study

Int J Palliat Nurs. 2026 Apr 2;32(4):184-193. doi: 10.12968/ijpn.2024.0032. Epub 2026 Apr 14.ABSTRACTBACKGROUND: Birthing a baby with an incurable heart condition can be very stressful for the parents. Healthcare providers should find practical solutions to support these parents and assist them in m

M Maryam Ahmadipour

Performance of PREVENT Cardiovascular Risk in Electronic Health Record-Based Clinical Practice

JAMA Netw Open. 2026 Apr 1;9(4):e266838. doi: 10.1001/jamanetworkopen.2026.6838.ABSTRACTIMPORTANCE: In 2023, the American Heart Association Cardiovascular-Kidney-Metabolic Scientific Advisory Group introduced the Predicting Risk of Cardiovascular Disease Events (PREVENT) equations, a race-free, sex-

C Chuan Hong

Mechanism(s) of factor XI inhibition in clinical practice

No abstractBlood Adv. 2026 Apr 14;10(7):2538-2540. doi: 10.1182/bloodadvances.2025019213.NO ABSTRACTPMID:41979876 | DOI:10.1182/bloodadvances.2025019213

R Richard C Becker

Bidirectional associations between biological aging, cardiovascular health, and cardiovascular risk: findings from the INSPIRE-T lifespan cohort

Geroscience. 2026 Apr 14. doi: 10.1007/s11357-026-02251-6. Online ahead of print.ABSTRACTChronological age is a common and non-modifiable factor for chronic disease, but does not fully explain age-related changes. Biological clocks have been developed to explore biological aging mechanisms. They cou

M Mathilde Strumia

Effect of inspiratory muscle training on fatigue, aerobic capacity, pulmonary functions, and quality of life in adolescents with familial Mediterranean fever: a randomized controlled trial

No abstractIr J Med Sci. 2026 Apr 14. doi: 10.1007/s11845-026-04360-9. Online ahead of print.NO ABSTRACTPMID:41979792 | DOI:10.1007/s11845-026-04360-9

A Ali Mohamed Ali Ismail

Correction: Effect of Metabolic Bariatric Surgery on Cardiovascular Outcomes in People with Obesity and Pre-existing Cardiovascular Disease: A Systematic Review and Meta-Analysis : Shurjeel Uddin Qazi

No abstractObes Surg. 2026 Apr 14. doi: 10.1007/s11695-026-08676-4. Online ahead of print.NO ABSTRACTPMID:41979775 | DOI:10.1007/s11695-026-08676-4

S Shurjeel Uddin Qazi

Analysis of Blood Group Antigens as Risk Factors for Thrombosis in Polycythemia Vera Patients

Clin Lab. 2026 Apr 1;72(4). doi: 10.7754/Clin.Lab.2025.250638.ABSTRACTBACKGROUND: Polycythemia vera (PV) is characterized by the abnormal proliferation of red blood cells (RBCs). Thrombosis and associated cardiovascular diseases are leading causes of mortality in patients with PV. This study aimed t

J Jay Ho Han

A Case of Waldenström's Macroglobulinemia Detected by the "Negative Creatinine" Alarm of Biochemical Results

Clin Lab. 2026 Apr 1;72(4). doi: 10.7754/Clin.Lab.2025.250578.ABSTRACTBACKGROUND: Test results and outliers are of great significance to disease diagnosis, especially in some inconspicuous hematological diseases. This report presents a case of Waldenström's macroglobulinemia diagnosed following abno

T Tong T Wang

Novel Basophilic Crystals in Acute Myeloid Leukemia with EZH2/DNMT3A Mutations: Aggressive Case with Thrombosis

Clin Lab. 2026 Apr 1;72(4). doi: 10.7754/Clin.Lab.2025.250653.ABSTRACTBACKGROUND: This study reports a novel case of EZH2/DNMT3A-mutated AML featuring unique basophilic rectangular crystals in blasts, associated with aggressive disease and thrombotic complications.METHODS: A 56-year-old male underwe

Z Zhiqing Liu

Sudden Unexpected Death due to Brainstem Hemorrhage Associated with Cerebral Venous Malformation

Clin Lab. 2026 Apr 1;72(4). doi: 10.7754/Clin.Lab.2025.250609.ABSTRACTBACKGROUND: Cerebral venous malformations (CVMs) generally remain silent and asymptomatic in the vast majority of cases. CVM-associated lethal intracerebral hemorrhage is extremely rare.METHODS: Here we presented a case with chest

Y Yanzhen Wan