Eur J Ophthalmol. 2025 Dec 1:11206721251403039. doi: 10.1177/11206721251403039. Online ahead of print.ABSTRACTPurposeTo investigate the association between PREVENT, a cardiovascular disease (CVD) risk estimation model, and quantitative parameters derived from choroidal vascular imaging.MethodsWe con
Mol Cell Biochem. 2025 Dec 1. doi: 10.1007/s11010-025-05451-4. Online ahead of print.ABSTRACTThe inter-disciplinary relationship between the gut microbiota, mitochondrial function, and inflammation activation represents a frontier in understanding Cardiovascular complications. This comprehensive rev
Am J Clin Dermatol. 2025 Dec 1. doi: 10.1007/s40257-025-00996-y. Online ahead of print.ABSTRACTPsoriasis is a systemic inflammatory disease increasingly recognized for its association with elevated cardiovascular risk, driven by immune-mediated endothelial dysfunction and accelerated atherosclerosis
Int J Cardiovasc Imaging. 2025 Dec 1. doi: 10.1007/s10554-025-03574-9. Online ahead of print.ABSTRACTBackground To investigate a potential association of Positron Emission Tomography (PET)-determined classical and endogen type of coronary microvascular dysfunction (CMD) and cardiovascular outcome in
Inflammopharmacology. 2025 Dec 1. doi: 10.1007/s10787-025-02046-9. Online ahead of print.ABSTRACTReactive oxygen species (ROS) and nitrogen-derived oxidants, such as nitric oxide (NO), are produced by immune cells through the activation of nicotinamide adenine dinucleotide phosphate (NADPH) oxidases
Front Med. 2025 Dec 1. doi: 10.1007/s11684-025-1167-x. Online ahead of print.ABSTRACTDirect evidence regarding ion channel-mediated initiation of baroreflex/visceral neurotransmission remains limited. Here, aortic-arch, vagus-nodose slice, and isolated neurons were employed with single-fiber/whole-c
Metabolomics. 2025 Dec 1;22(1):2. doi: 10.1007/s11306-025-02362-9.ABSTRACTINTRODUCTION: Ischemic stroke (IS) is a leading cause of disability and mortality. Metabolomics, in conjunction with machine learning (ML), can be employed to identify potential biomarkers associated with this condition.OBJECT
J Neuroimmune Pharmacol. 2025 Dec 1;20(1):107. doi: 10.1007/s11481-025-10267-6.ABSTRACTDiabetes mellitus exacerbates cerebral ischemic damage by potentiating neuroinflammation. We hypothesized that activation of the bradykinin type 2 receptor, a mediator of inflammation and vascular dynamics, might
No abstractIn Vitro Cell Dev Biol Anim. 2025 Dec 1. doi: 10.1007/s11626-025-01131-1. Online ahead of print.NO ABSTRACTPMID:41324798 | DOI:10.1007/s11626-025-01131-1
Curr Cardiol Rep. 2025 Dec 1;27(1):169. doi: 10.1007/s11886-025-02316-6.ABSTRACTPURPOSE OF REVIEW: This review aims to provide a comprehensive overview of mavacamten in the management of obstructive hypertrophic cardiomyopathy (oHCM), from its molecular mechanism of action to clinical trial outcomes
Mol Neurobiol. 2025 Dec 1;63(1):231. doi: 10.1007/s12035-025-05424-0.ABSTRACTAlzheimer's disease (AD), a progressive neurodegenerative disease characterized by the gradual deterioration of memory, imposes a significant global socioeconomic burden. Despite mechanistic insights into amyloid-β (Aβ) and
Curr Hypertens Rep. 2025 Dec 1;27(1):28. doi: 10.1007/s11906-025-01342-7.ABSTRACTPURPOSE OF REVIEW: Hypertension is the leading modifiable risk factor for cardiovascular disease. Despite multiple antihypertensive therapies, blood pressure (BP) control remains suboptimal in many individuals with pers
Curr Hypertens Rep. 2025 Dec 1;27(1):29. doi: 10.1007/s11906-025-01348-1.ABSTRACTPURPOSE OF REVIEW: Blood pressure (BP) is involved in the pathogenesis of cerebral small vessel disease (CSVD) and clinical research confirms this strong correlation. Data showing whether daytime or nighttime BP is the
Eur J Nutr. 2025 Dec 1;64(8):324. doi: 10.1007/s00394-025-03754-2.ABSTRACTPURPOSE: To reduce the risk of recurrent cardiovascular events in patients with established cardiovascular disease (CVD), guidelines recommend adopting a more plant-based diet. The EAT-Lancet diet, which focuses on plant-based
Neurochem Res. 2025 Dec 1;51(1):8. doi: 10.1007/s11064-025-04610-9.ABSTRACTThis study aims to investigate the neuroprotective effect of 6-shogaol (6-SH) in rats after cardiopulmonary resuscitation (CPR), and to explore the molecular mechanism by which it regulates the miRNA-26a-5p/DAPK1 to inhibit e
Naunyn Schmiedebergs Arch Pharmacol. 2025 Dec 1. doi: 10.1007/s00210-025-04795-4. Online ahead of print.ABSTRACTDiabetes is characterized by increased blood glucose levels (hyperglycemia) linked with insufficient insulin secretion or action. Diabetes has become a major health concern in the twenty-f
Childs Nerv Syst. 2025 Dec 1;41(1):392. doi: 10.1007/s00381-025-07060-4.ABSTRACTBACKGROUND: Tuberous sclerosis complex (TSC) is an autosomal dominant, multiorgan neurocutaneous syndrome. Intracranial aneurysms associated with TSC are extremely rare, and most reports are limited to single cases. The
Ideggyogy Sz. 2025 Nov 30;78(11-12):389-393. doi: 10.18071/isz.78.0389.ABSTRACTBACKGROUND AND PURPOSE: An unpleasant symptom of prostate hyperplasia is that older men get up to urinate at night. However, from the point of view of wake-up stroke, this can be an advantage, as they can detect their neu
JACC Cardiovasc Imaging. 2025 Nov 22:S1936-878X(25)00579-0. doi: 10.1016/j.jcmg.2025.09.021. Online ahead of print.ABSTRACTBACKGROUND: The severity and extent of whole heart coronary plaque volume and stenosis can be reliably measured by artificial intelligence-guided quantitative coronary computed
JACC Cardiovasc Imaging. 2025 Nov 26:S1936-878X(25)00636-9. doi: 10.1016/j.jcmg.2025.10.024. Online ahead of print.ABSTRACTMasters athletes (MAs), defined as individuals ≥35 years of age who are engaged in competitive or high-volume recreational sports or exercise training, comprise a growing group
JACC Cardiovasc Imaging. 2025 Nov 24:S1936-878X(25)00594-7. doi: 10.1016/j.jcmg.2025.10.012. Online ahead of print.ABSTRACTBACKGROUND: The effects of statin therapy on pericoronary adipose tissue (PCAT) and its relationship with plaque progression and outcomes in people with HIV (PWH) remain poorly
No abstractJACC Cardiovasc Imaging. 2025 Nov 19:S1936-878X(25)00596-0. doi: 10.1016/j.jcmg.2025.10.014. Online ahead of print.NO ABSTRACTPMID:41324517 | DOI:10.1016/j.jcmg.2025.10.014
Blood Press. 2025 Dec 1:1-12. doi: 10.1080/08037051.2025.2598105. Online ahead of print.ABSTRACTEpigenetic modifications are known to contribute to the pathophysiology of hypertension. Only a few studies that have been done to comprehensively evaluate the possibility role of epigenetic changes on th
Hum Mol Genet. 2025 Dec 1:ddaf177. doi: 10.1093/hmg/ddaf177. Online ahead of print.ABSTRACTThe causal effect of lower plasma sclerostin on cardiovascular disease (CVD) risk has previously been examined with the aim of investigating potential side effects of pharmacological sclerostin inhibition for
