Orforglipron for the treatment of moderate-to-severe obstructive sleep apnea in adults with obesity or overweight: Study design and baseline characteristics of ATTAIN-OSA, a phase 3 trial

Contemp Clin Trials Commun. 2026 Jun 19;52:101660. doi: 10.1016/j.conctc.2026.101660. eCollection 2026 Aug.ABSTRACTINTRODUCTION: Obstructive sleep apnea (OSA) is highly prevalent, yet current treatment remains limited. Poor adherence to positive airway pressure (PAP) and barriers associated with inj

A Atul Malhotra

Hypertension among Middle Eastern and North African adults residing in the United States: addressing equity in health research representation using the All of Us Research Program, 2000-2024

Front Med (Lausanne). 2026 Jun 16;13:1819597. doi: 10.3389/fmed.2026.1819597. eCollection 2026.ABSTRACTBACKGROUND: Hypertension (HTN) is a leading modifiable risk factor for cardiovascular disease and mortality; however, its epidemiology among the Middle Eastern and North African (MENA) population r

E Eissa A Jafari

2021 Clinical Practice Guidelines on Periodic Health Examination

Acta Med Philipp. 2026 May 30;60(10):7-27. doi: 10.47895/amp.v60i10.12061. eCollection 2026.ABSTRACTBACKGROUND AND OBJECTIVE: The first Philippine Guidelines on Periodic Health Examination (PHEX) provided evidence-based recommendations for prevention strategies in the Philippines, published in 2004.

I Ian Theodore G Cabaluna

Atrial fibrillation and cardiovascular comorbidity burden as predictors of in-hospital mortality in acute pancreatitis: A National Inpatient Sample analysis of 1.9 million hospitalizations

Int J Cardiol Cardiovasc Risk Prev. 2026 Jun 18;30:200662. doi: 10.1016/j.ijcrp.2026.200662. eCollection 2026 Sep.ABSTRACTBACKGROUND: Atrial fibrillation (AF) and cardiovascular (CV) comorbidities are prevalent in acute pancreatitis (AP) and may compromise hemodynamic tolerance of systemic inflammat

B Brett David Cohen

Incretin-Based Therapies in Obesity-Related Heart Failure With Preserved Ejection Fraction (HFpEF): A Systematic Review of Emerging Cardiometabolic Disease Modification Beyond Glycemic Control

Cureus. 2026 May 31;18(5):e109953. doi: 10.7759/cureus.109953. eCollection 2026 May.ABSTRACTHeart failure with preserved ejection fraction (HFpEF) remains a clinically heterogeneous syndrome with limited disease-modifying therapeutic options, particularly among patients with obesity-related cardiome

V Vaishnavi Hemdev

DOCK8 in immune cells: roles and mechanisms

Front Immunol. 2026 Jun 16;17:1854442. doi: 10.3389/fimmu.2026.1854442. eCollection 2026.ABSTRACTDOCK8 (dedicator of cytokinesis 8) is a prominent member of the DOCK-C subfamily and functions as an atypical guanine nucleotide exchange factor (GEF). It primarily activates Rho family small GTPases-mos

Z Zixuan Liao

Autism screening and diagnosis in children with congenital heart disease

Front Pediatr. 2026 Jun 16;14:1839114. doi: 10.3389/fped.2026.1839114. eCollection 2026.ABSTRACTAIM: This study determined the prevalence of positive autism screening results at 18-30 months of age and the presence of an autism diagnosis among children with congenital heart disease (CHD).METHODS: Se

N Nuria Lisset Ontiveros Perez

Closing the quality gap: analysis of implementation barriers and interventions for postoperative exercise rehabilitation for patients with radiofrequency ablation for atrial fibrillation

Front Cardiovasc Med. 2026 Jun 16;13:1757839. doi: 10.3389/fcvm.2026.1757839. eCollection 2026.ABSTRACTBACKGROUND: Atrial fibrillation patients often experience issues such as recurrence and reduced exercise tolerance following radiofrequency catheter ablation, which adversely affect postoperative r

B Bingqing Lu

Persistent Severe Tricuspid Regurgitation After Mitral Transcatheter Edge-to-Edge Repair: Prognostic Implications of Guideline-Based Eligibility for Transcatheter Tricuspid Valve Intervention

Struct Heart. 2026 May 22;10(7):101051. doi: 10.1016/j.shj.2026.101051. eCollection 2026 Jul.ABSTRACTBACKGROUND: Persistent tricuspid regurgitation (TR) after mitral transcatheter edge-to-edge repair (M-TEER) is common and associated with adverse outcomes. However, the prognostic relevance of persis

M Moritz Kühlein