Statins are associated with decreased risk of disease progression and death in non-cirrhotic patients with primary biliary cholangitis

Eur J Intern Med. 2026 Oct 3:107219. doi: 10.1016/j.ejim.2026.107219. Online ahead of print.ABSTRACTBACKGROUND/AIMS: We evaluated whether statins in non-cirrhotic patients with primary biliary cholangitis (PBC) might influence disease progression, including cirrhosis development, hepatic decompensat

E Eirini I Rigopoulou

Marked Variability in Lipid Profile Reporting Among Australian Pathology Providers: A National Cross-Sectional Review of Low-Density Lipoprotein Cholesterol

Heart Lung Circ. 2026 Oct 3:S1443-9506(26)00460-9. doi: 10.1016/j.hlc.2026.05.025. Online ahead of print.ABSTRACTBACKGROUND: Lipid profiles facilitate cardiovascular risk stratification, therapeutic monitoring, and patient education. Variability in pathology reporting practices may generate confusio

J Jeff R Ma

Changing Patterns of Causes of Death in Patients With Multiple Myeloma During the Modern Therapeutic Era

Clin Lymphoma Myeloma Leuk. 2026 Sep 11:S2152-2650(26)03290-8. doi: 10.1016/j.clml.2026.09.004. Online ahead of print.ABSTRACTBACKGROUND: Therapeutic advances have substantially prolonged survival in multiple myeloma (MM). However, real-world evidence on temporal changes in causes of death remains l

A Abel Rosado-Rodriguez

Patency and functional outcomes of endovascular treatment in juxta-anastomotic venous stenosis of native arteriovenous fistulas

Nefrologia (Engl Ed). 2026 Oct;46(8):501536. doi: 10.1016/j.nefroe.2026.501536.ABSTRACTINTRODUCTION: Juxta-anastomotic venous stenosis is a frequent cause of dysfunction in native arteriovenous fistula (AVFs), compromising both maturation and long-term patency. Endovascular treatment has emerged as

I Iván Zamora

Haemodynamic and neurophysiological assessments for 2-year outcome prediction in neonates with hypoxic-ischaemic encephalopathy treated with therapeutic hypothermia: a systematic review and meta-analysis

BMJ Paediatr Open. 2026 Oct 3;10(1):e004810. doi: 10.1136/bmjpo-2026-004810.ABSTRACTOBJECTIVE: To evaluate the prognostic accuracy of amplitude-integrated electroencephalography (aEEG), cerebral near-infrared spectroscopy (cNIRS) and targeted neonatal echocardiography (TnECHO) for predicting 2-year

M Mona Noureldein

Development and Evaluation of a Trauma-Informed Women's Health Education Program for Intimate Partner Violence Survivors: A Mixed-Methods Study

Violence Vict. 2026 Oct 3:VV-2025-0100.R1. doi: 10.1891/VV-2025-0100. Online ahead of print.ABSTRACTWomen with a history of intimate partner violence (IPV) are at increased risk for cardiovascular disease, human papillomavirus (HPV), cervical cancer, and human immunodeficiency virus (HIV), which we

S Sarah Joseph

A Tribute by The Editorial Board of the American Journal of Medicine. Our Retrospective and an Interview with the Outgoing Editor, Joseph S. Alpert, MD MACP

No abstractAm J Med. 2026 Oct 3:S0002-9343(26)00678-9. doi: 10.1016/j.amjmed.2026.09.016. Online ahead of print.NO ABSTRACTPMID:42829131 | DOI:10.1016/j.amjmed.2026.09.016

R Richard D deShazo

Thrombin Generation in Critically Ill Adults: A Systematic Review of Venous Thromboembolism and Pharmacological Thromboprophylaxis

J Thromb Haemost. 2026 Oct 3:S1538-7836(26)00627-6. doi: 10.1016/j.jtha.2026.09.037. Online ahead of print.ABSTRACTBACKGROUND: Venous thromboembolism (VTE) remains an important complication in critically ill adults despite standard pharmacological thromboprophylaxis. Thrombin generation assays (TGAs

C Caseng Zhang

CRISPR-based genome editing of smooth muscle cells: Disease models, therapeutic applications, and future perspectives

Vascul Pharmacol. 2026 Oct 3:107709. doi: 10.1016/j.vph.2026.107709. Online ahead of print.ABSTRACTSmooth muscle cells (SMCs) are essential for the normal function of the cardiovascular, respiratory, gastrointestinal, and urogenital systems, and SMC dysfunction contributes to a wide range of genetic

Q Qianqian Ding

Frailty-Related Metabolic Signature in the Association Between Frailty and Coronary Artery Disease: Modification by Genetic Susceptibility

J Nutr Health Aging. 2026 Oct 3;30(12):100998. doi: 10.1016/j.jnha.2026.100998. Online ahead of print.ABSTRACTBACKGROUND: Frailty is associated with increased coronary artery disease (CAD) risk, but the circulating metabolic features underlying the frailty-CAD relationship and their interplay with g

J Junchi Liu

Chronic sleep deprivation promotes atherosclerosis via NFIL3/RORgammat Axis mediated Th17/Treg imbalance, targeting IL-17A attenuates disease progression

Int Immunopharmacol. 2026 Oct 3;190:117496. doi: 10.1016/j.intimp.2026.117496. Online ahead of print.ABSTRACTBACKGROUND: Chronic sleep deprivation (CSD) is an independent risk factor for atherosclerotic cardiovascular disease, but the underlying mechanisms remain elusive. This study aimed to investi

X Xixi Liu

Deficiency of purinergic receptor P2X7 attenuates neointima hyperplasia in mice after carotid artery wire injury

Int Immunopharmacol. 2026 Oct 3;190:117498. doi: 10.1016/j.intimp.2026.117498. Online ahead of print.ABSTRACTVascular restenosis remains a major clinical challenge following interventional treatments for cardiovascular diseases. While P2X7-mediated inflammatory responses have been implicated in vari

Z Zhongchen Luo

Rediscovering Kaposi Sarcoma in North Africa: Thirteen years of HIV-negative cases and survival insights from Morocco

Cancer Treat Res Commun. 2026 Oct 3;49:101466. doi: 10.1016/j.ctarc.2026.101466. Online ahead of print.ABSTRACTBACKGROUND: Kaposi sarcoma (KS) is a human herpesvirus 8 (HHV-8)-associated angioproliferative malignancy with distinct epidemiological and clinical variants. While HIV-associated KS has be

K Khaoula Oussama

Can tissue engineering applications replace cardiovascular medical devices? Searching for the key to clinical translation

Biomater Adv. 2026 Oct 1;191:215221. doi: 10.1016/j.bioadv.2026.215221. Online ahead of print.ABSTRACTCardiovascular diseases are the number one killer worldwide. Malfunction of the conduction system, heart valves, the myocardial muscle or the vessels irrigating the tissue have been traditionally ad

M María Flandes-Iparraguirre

A Knowledge Graph Framework for Longitudinal Congenital Heart Disease Modeling: Methodology Corner

JACC Adv. 2026 Oct 3;5(11 Pt 2):103291. doi: 10.1016/j.jacadv.2026.103291. Online ahead of print.ABSTRACTBACKGROUND: Congenital heart disease (CHD) is characterized by evolving clinical trajectories; staged interventions; and complex relationships among diagnoses, procedures, and encounters. Convent

H Hang Xu

Lifestyle strategies and nutraceuticals in chronic venous disease: an evidence-weighted synthesis and clinical positioning

Clin Nutr. 2026 Sep 18;66:106801. doi: 10.1016/j.clnu.2026.106801. Online ahead of print.ABSTRACTBACKGROUND AND AIMS: Chronic venous disease (CVD), including chronic venous insufficiency and venous leg ulcers (VLU), is common and substantially impairs quality of life. Compression is the cornerstone

F Federica Fogacci

Mechanistic reprogramming of the mtDNA-cGAS-STING axis in cellular senescence: from mitochondrial homeostatic disruption to inflammatory and immune outcomes

Biogerontology. 2026 Oct 3;27(5):171. doi: 10.1007/s10522-026-10515-z.ABSTRACTIn addition to cell cycle arrest, cellular senescence is characterized by disrupted mitochondrial homeostasis, development of the senescence-associated secretory phenotype (SASP), and alterations in the immune microenviron

Y Yapei Zhang

Obstetric and thrombotic outcomes among pregnant patients with myeloproliferative neoplasms: a propensity score matched real-world analysis

Ann Hematol. 2026 Sep 22;105(11):439. doi: 10.1007/s00277-026-07285-6.ABSTRACTPregnancies complicated by BCR::ABL1-negative myeloproliferative neoplasms (MPNs) are associated with increased maternal and thrombotic risk; however, large real-world comparative data remain limited. We performed a multic

N Nikhil Vojjala

Eosinophilia and the Heart: Evolving Concepts

Curr Cardiol Rep. 2026 Oct 3;28(1):103. doi: 10.1007/s11886-026-02423-y.ABSTRACTPURPOSE OF REVIEW: This review summarises recent advances in cardiac involvement in eosinophilia, with particular emphasis on pathophysiology, diagnostic challenges and therapeutic options.RECENT FINDINGS: Up to 43% of p

J Jan Habasko

Detection of serum amyloid A in Saliva of patients with internal carotid artery stenosis: a pilot study

Clin Oral Investig. 2026 Oct 3;30(10):503. doi: 10.1007/s00784-026-07202-1.ABSTRACTOBJECTIVES: To determine whether serum amyloid A (SAA) is detectable in saliva of patients with internal carotid artery (ICA) stenosis and to investigate the relationship between salivary and serum SAA levels across t

V Vrbanić Vrankić

Programmed cell death protein 4 (PDCD4): a pleiotropic regulator in cardiovascular diseases

J Physiol Biochem. 2026 Oct 3;82(1):100. doi: 10.1007/s13105-026-01237-4.ABSTRACTCardiovascular diseases (CVDs) remain the leading cause of morbidity and mortality worldwide, yet the molecular mechanisms are incompletely understood. Programmed cell death protein 4 (PDCD4), originally identified as a

M Mingbo Zheng

The Therapeutic Potential of MicroRNAs Delivered By Mesenchymal Stem Cells in Parkinson's Disease, Alzheimer's Disease, and Stroke: A Systematic Review of Preclinical Studies

Mol Neurobiol. 2026 Oct 3;63(1):944. doi: 10.1007/s12035-026-06247-3.ABSTRACTPopulation aging has led to a substantial increase in the prevalence of neurological disorders, including Parkinson's disease (PD), Alzheimer's disease (AD), and stroke. As current therapeutic strategies are largely limited

D Dominika Przywara

Association of Mixed Metal Exposures with Cardiovascular Disease: Insights from a Population-Based Study

Cardiovasc Toxicol. 2026 Oct 3;26(10):124. doi: 10.1007/s12012-026-10195-8.ABSTRACTEnvironmental metal exposure has been increasingly recognized as a contributor to cardiovascular toxicity, yet the effects of single and mixed metal burdens, as well as susceptible population subgroups, remain insuffi

X Xiandu Jin

Romosozumab Prescribing in Relation to Cardiovascular Disease History in Japan: A Nationwide Claims Database Study

Calcif Tissue Int. 2026 Oct 3;117(1):156. doi: 10.1007/s00223-026-01613-8.ABSTRACTConcerns regarding the cardiovascular safety of romosozumab have led to regulatory restrictions and precautionary guidance worldwide. In Japan, although a history of myocardial infarction or stroke is not a formal cont

Y Yuki Fujita