Vitamin C and cardiovascular disease
No abstractEur Heart J. 2026 Aug 3:ehag594. doi: 10.1093/eurheartj/ehag594. Online ahead of print.NO ABSTRACTPMID:42545732 | DOI:10.1093/eurheartj/ehag594
Oxidative stress, aging, metabolism, SIRT1, and the gut microbiota: the neurocardiac basis of cognitive loss
Med Gas Res. 2026 Aug 3. doi: 10.4103/mgr.MEDGASRES-D-26-00073. Online ahead of print.ABSTRACTFactsCardiovascular disease, Alzheimer's disease, and multiple sclerosis share a neurocardiac basis linked by cellular metabolism and diabetes, indicating the presence of common pathological pathways.Curren
APOB to Estimated APOB Ratio for Screening for the APOE2 Genotype
Clin Chem. 2026 Aug 3:hvag094. doi: 10.1093/clinchem/hvag094. Online ahead of print.ABSTRACTBACKGROUND: Familial dysbetalipoproteinemia (FDB) is a genetic lipoprotein disorder that can develop in patients homozygous for the apolipoprotein 2 (APOE2) genotype (APOE ɛ2/ɛ2). It is associated with decrea
Hydrogels: current biomedical applications and future directions
Mol Biomed. 2026 Aug 3;7(1):123. doi: 10.1186/s43556-026-00525-1.ABSTRACTHydrogels are highly hydrated three-dimensional polymeric network materials that have attracted considerable attention in medical and biomedical fields owing to their favorable chemical modifiability, physical tunability, bioco
Dysregulation of ferroptosis-related plasma biomarkers in treatment-free patients with relapsing-remitting multiple sclerosis in clinical remission: a case-control study
Acta Neurol Belg. 2026 Aug 3. doi: 10.1007/s13760-026-03150-5. Online ahead of print.ABSTRACTBACKGROUND: Ferroptosis, an iron-dependent form of programmed cell death characterized by lipid peroxidation, has emerged as a key mechanism associated with neuroinflammation. This process is particularly re
Myocardial fibrosis in patients with coronary artery disease and diabetes mellitus assessed by cardiovascular magnetic resonance T1 mapping
Int J Cardiovasc Imaging. 2026 Aug 3. doi: 10.1007/s10554-026-03789-4. Online ahead of print.ABSTRACTThis study aimed to investigate the severity of myocardial fibrosis in patients with coronary heart disease (CHD) combined with diabetes mellitus (DM) using cardiovascular magnetic resonance (CMR) T1
Unsuccessful percutaneous left atrial appendage occlusion: A single center perspective
J Interv Card Electrophysiol. 2026 Aug 3. doi: 10.1007/s10840-026-02407-6. Online ahead of print.ABSTRACTBACKGROUND: Epicardial and endocardial left atrial appendage occlusion (LAAO) is commonly performed for stroke prevention for atrial fibrillation (AF) patients at increased risk for stroke who ca
Isoquercitrin suppresses neuronal ferroptosis in ischemic stroke via SIRT1-mediated deacetylation of H3K9 at the RBM15 promoter
Daru. 2026 Aug 3;34(2):54. doi: 10.1007/s40199-026-00629-7.ABSTRACTBACKGROUND: Isoquercitrin (ISO), a neuroprotective flavonoid, alleviates ischemic stroke (IS) by inhibiting ferroptosis. In present study, we explored the mechanism of ISO attenuates neuronal ferroptosis in IS.METHODS: HT22 cells and
Time in tight range and time in range in relation to diabetic retinopathy and OCTA-derived retinal microvascular parameters in hospitalized adults with type 1 diabetes
Endocrine. 2026 Aug 3;91(1):248. doi: 10.1007/s12020-026-04735-z.ABSTRACTAIM: Time in Tight Range (TITR) is physiologically closer to normoglycemia than time in range (TIR) and has been linked to microvascular risk. We aimed to evaluate associations of TITR with diabetic retinopathy (DR) and optical
Global Research Hotspots and Trends in Obesity-Related Venous Thromboembolism (2000-2025): a Bibliometric Analysis
Obes Surg. 2026 Aug 3. doi: 10.1007/s11695-026-08879-9. Online ahead of print.ABSTRACTINTRODUCTION: Obesity is closely associated with venous thromboembolism (VTE), yet no studies have thoroughly investigated this specific area or identified potential future research trends. This study aims to addre
Expert Consensus on Obesity Management Protocols - A Joint Position Statement by Obesity and Metabolic Surgery Society of India (OSSI) and Endocrine Society of India (ESI)
Obes Surg. 2026 Aug 3. doi: 10.1007/s11695-026-08870-4. Online ahead of print.ABSTRACTBACKGROUND: Obesity in India is rising rapidly, with higher body fat at lower BMI and younger age compared to Western populations, leading to earlier onset of type 2 diabetes and cardiovascular disease in a resourc
Cardiovascular Care in Multiple Myeloma: A Comprehensive Review and Integrated Systems-Based Approach from a UK Cardio-Oncology Centre of Excellence
Curr Cardiol Rep. 2026 Aug 3;28(1):75. doi: 10.1007/s11886-026-02397-x.ABSTRACTPURPOSE OF REVIEW: This review examines cardiovascular complications of multiple myeloma and anti-myeloma therapy, emphasising integrated systems-based cardiovascular management and the institutional model developed at th
Endoplasmic reticulum stress is associated with cardiac effects of bisphenol S independently of a high-fat diet
Histochem Cell Biol. 2026 Aug 3;164(1):70. doi: 10.1007/s00418-026-02525-2.ABSTRACTObesity and endocrine disruptors (EDs) promote endoplasmic reticulum (ER) stress, a mechanism associated with cardiovascular diseases. Among EDs, BPS is widely used in consumer products. Whether BPS promotes cardiac E
The Influence of Patient Persona and Affective Framing on Management Recommendations of ChatGPT, Gemini and Claude for Unruptured Intracranial Aneurysms: A Comparative Benchmarking Study
Neurosurg Rev. 2026 Aug 3;49(1):508. doi: 10.1007/s10143-026-04419-2.ABSTRACTPatients increasingly consult large language models (LLMs) before specialist review and may do so in widely differing emotional registers. We examined whether re-casting an unruptured intracranial aneurysm (UIA) case from a
Risk prediction of traumatic and non-traumatic subdural hematoma after ischemic stroke: a nationwide competing-risk model with external validation
Neurosurg Rev. 2026 Aug 3;49(1):505. doi: 10.1007/s10143-026-04414-7.ABSTRACTSubdural hematoma (SDH) represents a growing hemorrhagic concern among ischemic stroke survivors receiving long-term antithrombotic therapy. Although aging, multimorbidity, and antithrombotic exposure are all contributors t
The efficacy of ERAS-related components in orthopedic trauma surgery: a systematic review and meta-analysis of randomized controlled trials
Eur J Orthop Surg Traumatol. 2026 Aug 3;36(1):322. doi: 10.1007/s00590-026-04895-8.ABSTRACTBACKGROUND: Orthopaedic trauma surgery is associated with significant perioperative morbidity, prolonged hospital stays, and increased healthcare costs. Enhanced Recovery After Surgery (ERAS) protocols have sh
Covered Stent Implantation in a Preemie with Aortic Coarctation and Huge Patent Ductus Arteriosus: A Single Solution for Two Lesions
Pediatr Cardiol. 2026 Aug 3. doi: 10.1007/s00246-026-04407-9. Online ahead of print.ABSTRACTSevere aortic coarctation in premature infant is a very challenging clinical situation. Surgery is the standard treatment, however it carries high complications rate particularly in presence of other comorbid
Cross-population proteome-wide mendelian randomization study identifies likely causal proteins for cardiovascular diseases
Mol Genet Genomics. 2026 Aug 3;301(1):164. doi: 10.1007/s00438-026-02458-4.ABSTRACTBlood proteins may play causal roles in cardiovascular diseases (CVDs) such as heart failure (HF) and peripheral artery disease (PAD). Proteome-wide Mendelian randomization (MR) has been widely used to prioritize drug
Incident atrial fibrillation and pyoderma gangrenosum: long-term thromboembolic, heart failure, and mortality risk
Clin Res Cardiol. 2026 Aug 3. doi: 10.1007/s00392-026-02996-2. Online ahead of print.ABSTRACTBACKGROUND: Systemic inflammation is increasingly linked to atrial arrhythmogenesis, yet arrhythmic risk and downstream cardiovascular complications remain poorly quantified for inflammatory diseases managed
Outcomes of left atrial appendage closure in patients with prior mitral valve interventions
Clin Res Cardiol. 2026 Aug 3. doi: 10.1007/s00392-026-02979-3. Online ahead of print.ABSTRACTBACKGROUND: Data on left atrial appendage closure (LAAC) in valvular patients remain limited. This study aimed to evaluate procedural safety and outcomes of LAAC in patients with and without prior mitral val
Nonexercise prediction equation for oxygen uptake at anaerobic threshold in Chinese patients with cardiovascular disease
CONCLUSIONS: This study presents the first nonexercise VO(2)AT prediction equation for Chinese CVD patients, offering a new tool for cardiac rehabilitation and potential risk stratification.Eur J Appl Physiol. 2026 Aug 3. doi: 10.1007/s00421-026-06262-1. Online ahead of print.ABSTRACTBACKGROUND: Oxy
Hypertrophic cardiomyopathy-linked Tnnc1 variants are associated with distinct myopathic changes in slow skeletal muscle of mice
J Muscle Res Cell Motil. 2026 Aug 3;47(3):18. doi: 10.1007/s10974-026-09736-z.ABSTRACTInherited hypertrophic cardiomyopathy (HCM) is considered a disease of the cardiac sarcomere and caused by pathogenic variants present in genes that encode sarcomeric proteins. The human TNNC1 gene is a designated
Thrombolytic resistance: an important factor leading to the failure of intravenous thrombolytic therapy
J Neurol. 2026 Aug 3;273(8):501. doi: 10.1007/s00415-026-14052-0.ABSTRACTAcute ischemic stroke (AIS) is one of the most common nervous system diseases. Its high mortality and disability rates not only seriously threaten patients' health but also impose a significant socioeconomic burden. Intravenous
From Snapshots to Stories: Cardiovascular Risk Trajectories and the Future of Longitudinal Risk Prediction
No abstractMayo Clin Proc. 2026 Aug 3:S0025-6196(26)18592-9. doi: 10.1016/j.mayocp.2026.06.014. Online ahead of print.NO ABSTRACTPMID:42545301 | DOI:10.1016/j.mayocp.2026.06.014