Dysregulated circRNA expression profile and associated miRNA sponging in abnormal lung development in congenital diaphragmatic hernia

Clin Transl Med. 2026 Sep;16(9):e70752. doi: 10.1002/ctm2.70752.ABSTRACTRATIONALE: Circular RNAs (circRNAs) are stable, tissue- and developmental-stage-specific regulators of gene expression and candidate disease biomarkers. Their expression profile in abnormal lung development in congenital diaphra

M Marietta Jank

The effect of a tailored dietary intervention on serum biomarkers and faecal microbiome composition in people with HIV at risk of cardiovascular disease

HIV Med. 2026 Sep 11. doi: 10.1111/hiv.70291. Online ahead of print.ABSTRACTBACKGROUND: People with HIV (PWH) are at higher risk of cardiovascular disease (CVD) despite spontaneous or antiretroviral therapy-induced long-lasting suppressed viremia. Traditional and HIV-specific factors have been ident

F Fabio Antonino Ranzani

Safety of Nonsteroidal Anti-Inflammatory Drug Use in Traumatic Brain Injury

Pharmacotherapy. 2026 Oct;46(10):e70199. doi: 10.1002/phar.70199.ABSTRACTBACKGROUND: Use of nonsteroidal anti-inflammatory drugs (NSAIDs) after a traumatic brain injury (TBI) is controversial due to potential worsening of an intracranial hemorrhage (ICH). This study evaluated if NSAID use within 14

J Jennifer Beavers

Association Between CYP2C19 Genotype and P2Y12 Reaction Units in Patients Receiving Clopidogrel After Acute Ischemic Stroke: A Prospective, Observational Study

Pharmacotherapy. 2026 Oct;46(10):e70201. doi: 10.1002/phar.70201.ABSTRACTBACKGROUND: Recurrent stroke accounts for substantial morbidity and mortality worldwide, with up to 25% of ischemic strokes occurring in patients with prior strokes. Dual antiplatelet therapy (DAPT) with aspirin and clopidogrel

R Rachael M Stone

Temporal Mapping of CSVD-Related White Matter Lesions and Concurrent Neurovascular Dysfunction in Spontaneously Hypertensive Rats

CNS Neurosci Ther. 2026 Sep;32(9):e71142. doi: 10.1002/cns.71142.ABSTRACTOBJECTIVE: To define the critical onset window and mechanisms of white matter lesions (WMLs) in cerebral small vessel disease based on spontaneously hypertensive rat (SHR).METHODS: SHRs and age-matched Wistar-Kyoto (WKY) rats w

J Jing Peng

Association of Concomitant Amlodipine Use With Serum Olanzapine Concentrations and Clinical Outcomes in Patients With Schizophrenia

Hum Psychopharmacol. 2026 Sep;41(5):e70062. doi: 10.1002/hup.70062.ABSTRACTOBJECTIVE: To examine whether concomitant amlodipine use was associated with steady-state serum olanzapine concentration and clinical outcomes in patients with schizophrenia.METHODS: This retrospective study included 45 inpat

X Xiaoxiao Chen

FTH1 mRNA-Protein Discordance in Cardiac Ferroptosis: Multilayer Posttranscriptional and Degradative Control

Cardiovasc Ther. 2026;2026(1):e8306021. doi: 10.1155/cdr/8306021.ABSTRACTFerritin heavy Chain 1 (FTH1) is a key protective factor against ferroptosis in the heart, yet its protein abundance can diverge from transcript levels in cardiac ferroptosis contexts. Since resistance to ferroptosis depends on

F Feng Zhou

Clinical Impact of HRCT UIP Pattern Among Patients With Idiopathic Pulmonary Fibrosis Undergoing Antifibrotic Treatment: A Multicenter Retrospective Observational Study

Can Respir J. 2026;2026(1):e3604892. doi: 10.1155/carj/3604892.ABSTRACTBACKGROUND: Idiopathic pulmonary fibrosis (IPF) is a progressive fibrosing interstitial lung disease with a poor prognosis. Honeycombing on high-resolution computed tomography (HRCT) is a defining feature of the usual interstitia

S Satoshi Nagaoka

Autonomic cardiovascular changes during reactive hyperemia

Clin Physiol Funct Imaging. 2026 Sep;46(5):e70091. doi: 10.1111/cpf.70091.ABSTRACTPURPOSE: The objective of this study was to assess the variations in cardiovascular autonomic modulation during reactive hyperemia in diabetic patients with and without cardiovascular autonomic neuropathy (CAN).METHODS

E Erislandis López-Galán

Advanced Conduction Disease After Incident Heart Failure in Myotonic Dystrophy Type 1

Pacing Clin Electrophysiol. 2026 Sep 10. doi: 10.1111/pace.70421. Online ahead of print.ABSTRACTBACKGROUND: Myotonic dystrophy type 1 (DM1) is associated with progressive cardiac conduction disease, heart failure (HF) and increased mortality. However, the association of incident HF with conduction d

I Isadora Guarino

Symptom Network and Lesion Mapping of Post-Stroke Depression, Cognitive Impairment, and Dysfunction: A Multicenter Cohort Study

Brain Behav. 2026 Sep;16(9):e71759. doi: 10.1002/brb3.71759.ABSTRACTBACKGROUND: This study aimed to examine the interplay among depressive symptoms, cognitive impairment, and dysfunction after ischemic stroke using a network analysis approach, and to investigate whether selected network-derived targ

Q Qing Du

Blood Pressure Mediates the Association Between Carotid-Femoral Pulse Wave Velocity and Basal Ganglia Enlarged Perivascular Spaces: A Community-Based Cross-Sectional Study

J Clin Hypertens (Greenwich). 2026 Sep;28(9):e70363. doi: 10.1111/jch.70363.ABSTRACTAlthough carotid-femoral pulse wave velocity (cf-PWV) is the non-invasive gold standard for assessing aortic stiffness, evidence linking cf-PWV to basal ganglia enlarged perivascular spaces (BG-EPVS) in the general p

S Shang Li

Virtual Reality Reduces Office Blood Pressure and Anxiety in Patients Undergoing Ambulatory Blood Pressure Monitoring: Enhanced Response among Those With a Pronounced White Coat Response

J Clin Hypertens (Greenwich). 2026 Sep;28(9):e70360. doi: 10.1111/jch.70360.ABSTRACTOffice blood pressure (OBP) may be transiently elevated during clinical encounters because of situational anxiety and stress-related physiologic arousal, contributing to diagnostic uncertainty and potential overtreat

L Lyle Wesley Baker

Efficacy and Safety of a Single-Pill Triple Combination of Valsartan, Amlodipine, and Chlorthalidone in Patients With Essential Hypertension Inadequately Controlled on Dual Therapy With Valsartan and Amlodipine: A Randomized, Double-Blind, Multicenter, Phase 3 Trial

J Clin Hypertens (Greenwich). 2026 Sep;28(9):e70362. doi: 10.1111/jch.70362.ABSTRACTMany hypertensive patients require three or more antihypertensive agents to achieve target blood pressure. This randomized, double-blind, multicenter phase 3 trial conducted in South Korea evaluated the efficacy and

I In-Jeong Cho

Venous Thromboembolism in Severe Community-Acquired Pneumonia at High-Altitude Areas: Prevalence, Risk and Outcome

Clin Respir J. 2026 Sep;20(9):e70230. doi: 10.1111/crj.70230.ABSTRACTINTRODUCTION: High-altitude exposure and hypoxia may induce a hypercoagulable state, thereby promoting the development of venous thromboembolism (VTE). Few studies have reported the incidence of VTE among patients with severe commu

Y Yuntao Zhang

A Cross-Sectional Survey of Knowledge, Confidence, and Decision-Making in Acute Stroke in the Era of Anti-Amyloid Therapies

J Am Coll Clin Pharm. 2026 Oct;9(10):e70291. doi: 10.1002/jac5.70291.ABSTRACTBACKGROUND: Anti-amyloid therapies (AATs) for Alzheimer's disease complicate emergency stroke care due to the risk of amyloid-related imaging abnormalities (ARIA), which can mimic acute ischemic stroke (AIS) and increase he

P Preeyaporn Sarangarm

Genetically Predicted Muscle Mass and Function in Relation to Deep Vein Thrombosis: A Two-step Mendelian Randomization Study Highlighting the Mediating Role of BMI

Clin Appl Thromb Hemost. 2026 Jan-Dec;32:10760296261488557. doi: 10.1177/10760296261488557. Epub 2026 Sep 10.ABSTRACTBackgroundSarcopenia is observationally linked to venous thromboembolism, but the causal architecture and underlying biological pathways remain largely unclear. This study investigate

Q Qixiang Sun

Sex-related differences in echocardiography parameters for predicting in-hospital mortality in patients with acute pulmonary embolism

Ther Adv Respir Dis. 2026 Jan-Dec;20:17534666261486953. doi: 10.1177/17534666261486953. Epub 2026 Sep 10.ABSTRACTBackgroundRisk stratification of acute pulmonary embolism (PE) is primarily based on systolic arterial pressure, right ventricular (RV) function, and cardiac troponin levels.ObjectivesTo

K Kos Ljiljana

EXPRESS: Covert cerebral small vessel disease and outcomes after spontaneous intracerebral hemorrhage

J Cereb Blood Flow Metab. 2026 Sep 10:271678X261490344. doi: 10.1177/0271678X261490344. Online ahead of print.ABSTRACTThe prognostic implications of covert cerebral small vessel disease (SVD) in spontaneous intracerebral hemorrhage (ICH) remain unclear. We investigated associations of SVD markers wi

K Kaori Miwa

EXPRESS: Rapamycin increases cerebral blood flow and modulates metabolic, inflammatory, and microbiome profiles in healthy middle-aged APOE4 carriers: a pilot single-arm trial

J Cereb Blood Flow Metab. 2026 Sep 10:271678X261490342. doi: 10.1177/0271678X261490342. Online ahead of print.ABSTRACTCarriers of the apolipoprotein E4 (APOE4) allele often develop cerebrovascular dysfunction and broader systemic alterations decades before the onset of Alzheimer's disease (AD) patho

C Chetan Aware

The SGLT2i Treatment Gap in UK Primary Care: A Cross-Sectional RWE Study of Prescribing in Clinical Practice

Diabetes Obes Metab. 2026 Sep 10. doi: 10.1111/dom.71298. Online ahead of print.ABSTRACTAIMS: Sodium-glucose co-transporter 2 inhibitors (SGLT2i) improve cardiovascular and renal outcomes in type 2 diabetes mellitus (T2DM), chronic kidney disease (CKD) and chronic heart failure (CHF). Despite clinic

C Chelsea Stefanska

Communication Confidence, Aphasia Severity and Well-Being: A Cross-Sectional and Longitudinal Study in People With Post-Stroke Aphasia

Int J Lang Commun Disord. 2026 Sep-Oct;61(5):e70316. doi: 10.1111/1460-6984.70316.ABSTRACTBACKGROUND: Communication confidence is increasingly recognised as a clinically crucial yet under-researched topic in aphasiology. It has been reported to be one of the most valuable treatment outcomes by strok

S Sarah S AlFraih

Association Between Platelet Transfusion and ICU Mortality Within 28 Days Among Patients With Intracranial Hemorrhage Complicated by Thrombocytopenia: A Propensity Score-Matched Cohort Study

Med Sci Monit. 2026 Sep 11;32:e953547. doi: 10.12659/MSM.953547.ABSTRACTBACKGROUND Thrombocytopenia is common among patients with traumatic or non-traumatic intracranial hemorrhage admitted to the neuro-intensive care unit (neuro-ICU). The association between platelet transfusion and short-term outc

D Dachang Qiu

Survey of Actual Aspirin Use and Deep Vein Thrombosis in Patients with Pomalidomide-Containing Therapy Using a Medical Information Database

Gan To Kagaku Ryoho. 2026 Aug;53(8):512-516.ABSTRACTPomalidomide (POM) is an immunomodulatory drug used to treat multiple myeloma, and low-dose aspirin (ASA) is recommended as a preventive measure against its side effect, deep vein thrombosis (DVT). In this study, we utilized a medical information d

Y Yoji Kawase