Carnosine Augments the Efficacy of Pulmonary Rehabilitation in COPD: Insights from a Preclinical Model

Clin Sci (Lond). 2026 Apr 23:CS20260348. doi: 10.1042/CS20260348. Online ahead of print.ABSTRACTPulmonary rehabilitation (PR) improves exercise tolerance and dyspnoea in chronic obstructive pulmonary disease (COPD) but does not address the elevated cardiovascular disease (CVD) risk. Vascular dysfunc

R Ross Vlahos

Reporting of social demographics in diabetic foot ulcer randomized controlled trials: a scoping review

Wounds. 2026 Jan;38(1):1-6. doi: 10.25270/wnds/25020.ABSTRACTBACKGROUND: Diabetic foot ulcerations (DFUs) remain a major public health issue, disproportionately affecting diverse populations. The extent to which race, ethnicity, and social demographics are reported in randomized controlled trials (R

D Dominick J Casciato

Signal Detection Using Change Point Analysis to Identify Safety Signals from Spontaneous Reports in Aortic Stent Grafts in Japan

J Med Syst. 2026 Apr 23;50(1):61. doi: 10.1007/s10916-026-02388-z.ABSTRACTSignal detection is essential for identifying potential safety issues with drugs and medical devices. Change point analysis (CPA) detects changes in longitudinal data for a medical device without incorporating comparisons with

K Kohei Takahashi

Simultaneous pallidal and centromedian deep brain stimulation for combined dystonia and drug-resistant epilepsy in a child with hypoxic-ischemic encephalopathy: a technical case report

Childs Nerv Syst. 2026 Apr 23;42(1):175. doi: 10.1007/s00381-026-07250-8.ABSTRACTPURPOSE: Children with hypoxic-ischemic encephalopathy (HIE) frequently exhibit both dystonia and drug-resistant generalized epilepsy, reflecting injury to parallel but distinct motor and thalamocortical networks. Deep

J Jasmine L Hect

Association between bone health and cardiovascular events in a population-based cohort

Arch Osteoporos. 2026 Apr 23;21(1):70. doi: 10.1007/s11657-026-01704-x.ABSTRACTBrief rationale: Low bone mineral density may be linked to cardiovascular risk, but causality is unclear.MAIN RESULT: In 1233 individuals followed for 14 years, osteoporotic fractures and trabecular vBMD independently pr

Á Álex García Tellado

Visually-induced hemodynamic response and white matter hyperintensities in middle-aged women with ischemic stroke or migraine with aura

Cephalalgia. 2026 Apr;46(4):3331024261439256. doi: 10.1177/03331024261439256. Epub 2026 Apr 23.ABSTRACTBackgroundMigraine, especially with aura (MA), increases the risk of brain white matter hyperintensities (WMH) and ischemic stroke. Altered microvascular function has been proposed as a shared unde

N Nelleke van der Weerd

Whole genome sequencing analysis of over 3500 individuals dementia-free over 85 years old

J Alzheimers Dis. 2026 Apr 23:13872877261444302. doi: 10.1177/13872877261444302. Online ahead of print.ABSTRACTBackgroundIdentifying genetic variants conferring resilience to Alzheimer's disease and related dementia (ADRD) may hold promise for developing therapeutics.ObjectiveTo determine genetic as

G Gina M Peloso

A Central Somatic Transmission Mediates Proprioceptive Facilitation of Muscle Pain

Adv Sci (Weinh). 2026 Apr 23:e14242. doi: 10.1002/advs.202514242. Online ahead of print.ABSTRACTProprioception, often described as a sixth sense to perceive body position and muscle contraction, has been increasingly implicated in the development and maintenance of chronic pain, yet the underlying m

X Xiaoyu Zhang

Cardiac MRI for Preprocedural Assessment in Participants with Nonvalvular Atrial Fibrillation Undergoing Left Atrial Appendage Closure

Radiol Cardiothorac Imaging. 2026 Apr;8(2):e250475. doi: 10.1148/ryct.250475.ABSTRACTPurpose To evaluate the feasibility of cardiac MRI for preprocedural left atrial appendage closure (LAAC) planning and to compare cardiac MRI- and transesophageal echocardiography (TEE)-derived measurements. Materia

M Masahiko Asami

Sex-Specific Associations With Abnormal Myocardial Flow Reserve in Non-Obstructive Coronary Artery Disease: Insights From a Real-World Cadmium-Zinc-Telluride SPECT Study

Clin Cardiol. 2026 Apr;49(4):e70294. doi: 10.1002/clc.70294.ABSTRACTBACKGROUND: Coronary microvascular dysfunction (CMVD) is prevalent in non-obstructive coronary artery disease (NOCAD), and potential sex-related determinants remain incompletely characterized. This study explored sex-specific associ

Y Ya-Jie Wang

Incident Hypertension with Antiretroviral Therapy in the OPERA Cohort

J Int Assoc Provid AIDS Care. 2026 Jan-Dec;25:23259582261445148. doi: 10.1177/23259582261445148. Epub 2026 Apr 23.ABSTRACTPurpose of the researchTo compare incident hypertension rates across antiretroviral therapy regimens among adults with HIV in routine clinical care in the US-based OPERA cohort.M

G Gerald Pierone

Atherogenic Index of Plasma Predicts the Onset and Progression of Cardio-Renal-Metabolic Multimorbidity: Evidence From a Nationwide Prospective Cohort Study

J Diabetes. 2026 Apr;18(4):e70227. doi: 10.1111/1753-0407.70227.ABSTRACTBACKGROUND: Cardio-renal-metabolic (CRM) multimorbidity, defined by the co-occurrence of cardiovascular disease (CVD), chronic kidney disease (CKD), and type 2 diabetes (T2DM), poses a growing burden for multimorbidity managemen

J Jijie Jin

Integration to "Androgenetic alopecia in women and men: Italian guidelines adapted from European Dermatology Forum/European Academy of Dermatology and Venereology guidelines"

No abstractItal J Dermatol Venerol. 2026 Apr 23. doi: 10.23736/S2784-8671.26.08584-1. Online ahead of print.NO ABSTRACTPMID:42023888 | DOI:10.23736/S2784-8671.26.08584-1

M Michela Starace

Associations of C-reactive protein-triglyceride-glucose index cumulative burden with incident cardiovascular disease in middle-aged and older Chinese adults with abnormal glucose metabolism

Nutr Hosp. 2026 Apr 15. doi: 10.20960/nh.06533. Online ahead of print.ABSTRACTOBJECTIVE: the high-sensitivity C-reactive protein-triglyceride-glucose index (CTI) is a composite biomarker reflecting insulin resistance (IR) and systemic inflammation, both of which play critical roles in the developmen

H Hao Li

Terminal S-Wave Amplitude in Lead V2 With Monophasic R Waves in Other Precordial Leads: A Novel ECG Marker for Predicting Acute Successful Endocardial Ablation of a Subtype of Left Ventricular Outflow Tract Idiopathic Ventricular Arrhythmias

Clin Cardiol. 2026 Apr;49(4):e70332. doi: 10.1002/clc.70332.ABSTRACTBACKGROUND: An electrocardiographic (ECG) pattern-terminal s-wave in lead V2 with monophasic R waves in other precordial leads-may help identify a subset of left ventricular outflow tract (LVOT) idiopathic ventricular arrhythmias (I

C Chengye Di

Do Not Let Them Fall-ot: Emerging Role of Transcatheter Therapies in Adult Congenital Heart Diseases

No abstractJACC Case Rep. 2026 Apr 22;31(16):107735. doi: 10.1016/j.jaccas.2026.107735.NO ABSTRACTPMID:42023809 | DOI:10.1016/j.jaccas.2026.107735

G Giulio Russo

Spontaneous Coronary Artery Dissection or Coronary Atherosclerosis: Diagnostic Challenges in an Unclear Case

JACC Case Rep. 2026 Apr 22;31(16):107729. doi: 10.1016/j.jaccas.2026.107729. Epub 2026 Mar 16.ABSTRACTBACKGROUND: Spontaneous coronary artery dissection (SCAD) and atherosclerosis may appear similar on coronary imaging.CASE SUMMARY: A 62-year-old woman with fibromuscular dysplasia, dyslipidemia, and

M Maryam Taheri

Wearable SENsor to Diagnose and Assess SEverity of Aortic Stenosis (SENSE-AS): A Proof-of-Concept Study

JACC Adv. 2026 Apr;5(4):102699. doi: 10.1016/j.jacadv.2026.102699. Epub 2026 Mar 16.ABSTRACTBACKGROUND: Aortic stenosis (AS) is a common disease with delays in diagnosis and treatment. Wearable sensors may provide a scalable, noninvasive method to diagnose, assess severity, and monitor AS.OBJECTIVES

A Aniruddh Srinivasan

Providing Nutrition Guidance in the Absence of Conclusive Evidence: What Is a Clinician to Do?

No abstractJACC Adv. 2026 Apr;5(4):102670. doi: 10.1016/j.jacadv.2026.102670.NO ABSTRACTPMID:42023795 | DOI:10.1016/j.jacadv.2026.102670

L Lawerence J Appel

The Clinical Impact of Patent Foramen Ovale in Patients With Carcinoid Heart Disease

JACC Adv. 2026 Apr;5(4):102668. doi: 10.1016/j.jacadv.2026.102668. Epub 2026 Mar 16.ABSTRACTBACKGROUND: Carcinoid heart disease (CaHD) typically affects the right-sided valves. Rarely, CaHD affecting the left-sided valves has been observed in the setting of patent foramen ovale (PFO). However, the i

I Isabel G Scalia

Transport the thrombectomist to the patient

Lakartidningen. 2026 Apr 23;123:25148.ABSTRACTMechanical thrombectomy in acute ischemic stroke is highly effective and results in less disability compared to standard care. The treatment is time-sensitive, and delays lead to worse outcomes. Delivering mechanical thrombectomy in sparsely populated ru

B Boglárka Tot

Association of the Triglyceride-Glucose (TyG) Index and TyG-BMI With 1-Year Outcomes Following Endovascular Treatment in Acute Basilar Artery Occlusion

CNS Neurosci Ther. 2026 Apr;32(4):e70898. doi: 10.1002/cns.70898.ABSTRACTBACKGROUND: Long-term outcomes after endovascular treatment (EVT) in acute basilar artery occlusion (BAO) vary substantially, yet metabolic correlates remain incompletely characterized. This study evaluated whether the triglyce

Q Qiuting Wang

Next-Generation Albumin Hydrogels: Innovative Formulation Strategies and Therapeutic Applications for Various Diseases

ACS Appl Bio Mater. 2026 Apr 23. doi: 10.1021/acsabm.6c00260. Online ahead of print.ABSTRACTHydrogels have emerged as one of the most important and promising strategies for drug delivery and tissue engineering applications due to their unique physicochemical properties and intrinsic biocompatibility

V Vishal Babasaheb Galave

Neurogenic thoracic outlet syndrome secondary to an unilateral cervical rib in a poodle mix

J Vet Intern Med. 2026 Mar 2;40(2):aalag068. doi: 10.1093/jvimsj/aalag068.ABSTRACTA 2-year-old spayed female poodle mix was evaluated for persistent intermittent right thoracic limb lameness and pain refractory to oral analgesic and anti-inflammatory medications. Orthopedic and neurologic physical e

M Madeline McDermott