A multidomain early warning model for 12-month adverse outcomes in older adults with multimorbidity: a risk-stratified public health approach

Front Public Health. 2026 Sep 9;14:1841984. doi: 10.3389/fpubh.2026.1841984. eCollection 2026.ABSTRACTOBJECTIVE: To develop and internally validate a multidomain early warning model for 12-month adverse outcomes in older adults with multimorbidity, and to explore its potential for risk-stratified fo

M Miao-Miao Zhou

The perspectives of Lagos faith-institution leaders on health, hypertension, and faith-based hypertension interventions: a qualitative interview study

Front Public Health. 2026 Sep 9;14:1925205. doi: 10.3389/fpubh.2026.1925205. eCollection 2026.ABSTRACTINTRODUCTION: Hypertension remains a leading contributor to morbidity and mortality in Nigeria, where health system resources are constrained. Faith institutions wield considerable community influen

A Abayomi Sanusi

Rotating Night Shift Work and Risk of Incident Cardiovascular Disease and Mortality by Chronotype: A Prospective Cohort Study in Nurses' Health Study II

medRxiv [Preprint]. 2026 Sep 17:2026.09.16.26363233. doi: 10.64898/2026.09.16.26363233.ABSTRACTINTRODUCTION: Rotating night shift work is associated with chronic circadian disruption and may contribute to higher cardiovascular disease (CVD) risk and mortality. The impact of rotating night shift work

S Sina Kianersi

Association between dynamic estimated plasma volume trajectories and acute kidney injury after coronary artery bypass grafting

Front Med (Lausanne). 2026 Sep 9;13:1912347. doi: 10.3389/fmed.2026.1912347. eCollection 2026.ABSTRACTBACKGROUND: Cardiac surgery-associated acute kidney injury (CSA-AKI) is driven partly by venous congestion, yet no single bedside measure fully captures volume status: central venous pressure (CVP)

B Beijun Gao

Documenting HIV service delivery and adoption of evidence-based practices in HIV care programs: A protocol for a cross-sectional survey of HIV clinics participating in the International epidemiology Databases to Evaluate AIDS (IeDEA)

medRxiv [Preprint]. 2026 Sep 17:2026.09.16.26363245. doi: 10.64898/2026.09.16.26363245.ABSTRACTINTRODUCTION: HIV care and treatment programs around the world continue to evolve in response to changes in clinical guidelines, evidence-based practices, domestic and donor funding for the HIV response, n

E Ellen Brazier

Age-related changes in HPT axis sensitivity and their associations with metabolic and cardiovascular health: a cross-sectional, Chinese nationwide study

Front Endocrinol (Lausanne). 2026 Sep 9;17:1857191. doi: 10.3389/fendo.2026.1857191. eCollection 2026.ABSTRACTBACKGROUND: The regulation and secretion of hormones in the endocrine system change with aging. While these changes may influence age-related disease risks, the role of hypothalamic-pituitar

L Lei Zhao

Liver-eye axis in metabolic syndrome: integrated evidence from mendelian randomization, single-cell sequencing, and clinical sample validation

Front Endocrinol (Lausanne). 2026 Sep 9;17:1878316. doi: 10.3389/fendo.2026.1878316. eCollection 2026.ABSTRACTBACKGROUND: Non-alcoholic fatty liver disease (NAFLD) and diabetic retinopathy (DR) are common clinical complications of metabolic syndrome in different organ systems. However, the relations

T Tian-Hao Yuan

Establishment of a novel lupus mesenteric vasculitis mouse model and exploration of its exacerbation mechanisms

Front Immunol. 2026 Sep 9;17:1886325. doi: 10.3389/fimmu.2026.1886325. eCollection 2026.ABSTRACTLupus mesenteric vasculitis (LMV) is a gastrointestinal lesion primarily caused by vasculitis associated with systemic lupus erythematosus (SLE). In our preliminary experiments, we found that NZBWF1 (BWF1

M Maki Fujishiro

Reciprocal mediation of immuno-inflammation and insulin resistance in the risk of chronic kidney disease among patients with coronary artery disease: insights from neutrophil-to-lymphocyte ratio and triglyceride-glucose index

Front Immunol. 2026 Sep 9;17:1937248. doi: 10.3389/fimmu.2026.1937248. eCollection 2026.ABSTRACTOBJECTIVE: The neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), and triglyceride-glucose (TyG) index are used to evaluate the risk of coronary artery disease (CAD) or chronic kidn

X Xiaohong Chen

Antihypertensive Medication Class and Incident Alzheimer's Disease and Related Dementias: External Replication Across Two Independent Healthcare Data Sources-the Vanderbilt EHR Synthetic Derivative and US Medicare Claims

medRxiv [Preprint]. 2026 Sep 17:2026.09.11.26362859. doi: 10.64898/2026.09.11.26362859.ABSTRACTIMPORTANCE: Hypertension is among the most important modifiable risk factors for Alzheimer's disease and related dementias (ADRD), but whether different antihypertensive drug classes confer different cogni

A Anshul Tiwari

Dietary behavior patterns and short-term pace of aging-evidence from a Chinese cohort

Front Nutr. 2026 Sep 9;13:1924515. doi: 10.3389/fnut.2026.1924515. eCollection 2026.ABSTRACTBACKGROUND: Unhealthy dietary behaviors have been associated with increased risks of mortality and chronic diseases, yet mortality is a distal endpoint that requires long-term follow-up and is therefore poorl

X Xin Huang

Efficacy and safety of milrinone infusion in patients with aneurysmal subarachnoid hemorrhage: a systematic review and meta-analysis

Front Neurol. 2026 Sep 9;17:1872442. doi: 10.3389/fneur.2026.1872442. eCollection 2026.ABSTRACTBACKGROUND: Aneurysmal subarachnoid hemorrhage (aSAH) is a life-threatening neurological condition that can be complicated by delayed cerebral ischemia (DCI), a leading cause of secondary brain injury. Mil

K Khaled Gharaibeh

Exploring the Association of Angiotensin-(1-7) with Left Ventricular Mass Index in Youth with Hereditary Hypophosphatemia: A Pilot Study

Res Sq [Preprint]. 2026 Sep 20:rs.3.rs-10922460. doi: 10.21203/rs.3.rs-10922460/v1.ABSTRACTINTRODUCTION: Fibroblast growth factor 23 (FGF23) regulates phosphate homeostasis and is associated with cardiovascular-kidney-metabolic syndrome in patients with chronic kidney disease in part mediated by ang

S Sivaram Kumareswaran

Examining the Differences in Frequency of Whole Fruit or 100% Fruit Juice Intake among United States Adults With and Without Cardiovascular Disease Risk Factors: Analysis of 2019 Behavioral Risk Factor Surveillance System Data

Curr Dev Nutr. 2026 Aug 19;10(9):109517. doi: 10.1016/j.cdnut.2026.109517. eCollection 2026 Sep.ABSTRACTBACKGROUND: Nearly 80% of Americans do not meet recommendations for fruit, an important source of fiber, potassium, and vitamin C. In the 2020-2025 Dietary Guidelines for Americans, the fruit grou

B Brendan J Kesler

Whole-Blood Transcriptomics Highlights Galectin-1 in Systolic Blood Pressure

bioRxiv [Preprint]. 2026 Sep 16:2026.09.11.751025. doi: 10.64898/2026.09.11.751025.ABSTRACTBACKGROUND: Galectins regulate inflammation, fibrosis, immunity, and vascular remodeling. Although galectin-3 has been widely studied in cardiovascular disease, the relative contributions of other galectins to

A Amadou Gaye

Synthetic Echocardiograms from Diffusion Models in Rare Cardiovascular Disease

medRxiv [Preprint]. 2026 Sep 15:2026.09.14.26363024. doi: 10.64898/2026.09.14.26363024.ABSTRACTThe limited availability of imaging data for uncommon cardiovascular phenotypes constrains the development of robust imaging models. We evaluated whether class-conditional diffusion models can generate syn

P Pengfei Lyu

Uncovering a Sex-Specific cAMP Landscape in Vascular Smooth Muscle

bioRxiv [Preprint]. 2026 Sep 17:2026.09.11.751051. doi: 10.64898/2026.09.11.751051.ABSTRACTThe second messenger, cyclic adenosine monophosphate (cAMP), plays a crucial role in regulating cellular function, including in vascular smooth muscle (VSM). While extensive research has focused on the compart

E Eric A Pereira da Silva

Diet as a treatment for chronic kidney disease

Child Kidney Dis. 2024 Oct;28(3):112-115. doi: 10.3339/ckd.24.017. Epub 2024 Oct 31.ABSTRACTThe management of chronic kidney disease (CKD) includes nutritional interventions aimed at slowing disease progression and mitigating complications. This review examines various dietary approaches for CKD tre

J Jiwon Jung

How to delay the progression of chronic kidney disease: focusing on medications

Child Kidney Dis. 2024 Jun;28(2):51-58. doi: 10.3339/ckd.24.006. Epub 2024 Jun 13.ABSTRACTPatients with chronic kidney disease (CKD) bear a significant financial burden and face numerous complications and higher mortality rates. The progression of CKD is associated with glomerular injury caused by g

J Jeesu Min

Clinical Characteristics and Outcomes of Hypertrophic Cardiomyopathy Associated With Thin Filament Variants: Insights From the SHaRe Registry

Circ Genom Precis Med. 2026 Sep 24:e005696. doi: 10.1161/CIRCGEN.126.005696. Online ahead of print.ABSTRACTBACKGROUND: Conflicting evidence exists about whether sarcomeric hypertrophic cardiomyopathy (HCM) caused by genes encoding thin filament proteins (TNNT2, TNNI3, ACTC, TPM1, TNNC1; thin filamen

A Alessia Argirò

Associations of Brain Structure and Neuropsychological Function With Artificial Intelligence Estimates of Biological Vascular Age

Arterioscler Thromb Vasc Biol. 2026 Sep 24. doi: 10.1161/ATVBAHA.126.325247. Online ahead of print.ABSTRACTBACKGROUND: Accelerated vascular aging, assessed as artificial intelligence-based vascular age (AIVA), is associated with small vessel disease that may impact brain structure and neuropsycholog

L Leroy L Cooper

SMPD1 Inhibition Attenuates Abdominal Aortic Aneurysm via Ceramide-Mediated NLRP3 Inflammatory Pathway

Arterioscler Thromb Vasc Biol. 2026 Sep 24. doi: 10.1161/ATVBAHA.126.323961. Online ahead of print.ABSTRACTBACKGROUND: Abdominal aortic aneurysm (AAA) is a lethal cardiovascular disease with high heritability but no effective pharmacotherapy. We aimed to identify and experimentally validate AAA-asso

Z Zhiwen Yang

Air Pollution Triggers Metabolomic Signature of Mitochondrial Dysfunction in Mice and Humans: Implications for Cardiovascular Disease Development

Arterioscler Thromb Vasc Biol. 2026 Sep 24. doi: 10.1161/ATVBAHA.125.324277. Online ahead of print.ABSTRACTBACKGROUND: Previous animal studies found that subchronic exposure to diesel exhaust induces hyperlipidemia, accompanied by upregulation of 12-LOX (lipoxygenase) and 15-LOX pathways and hepatic

Y Yan Lin

Interleukin-17A, Interleukin-8, and Platelet Count Are Associated With Baseline Coronary Artery Lesions in Children With Kawasaki Disease: A Retrospective Exploratory Cohort Study

Immun Inflamm Dis. 2026 Sep;14(9):e70514. doi: 10.1002/iid3.70514.ABSTRACTBACKGROUND: Kawasaki disease (KD) is an acute childhood vasculitis in which coronary artery lesions (CALs) determine long-term cardiovascular risk. We evaluated a focused pre-IVIG biomarker profile in relation to baseline Z-sc

C Cuijie Gong