Insomnia is associated with altered arachidonic acid-induced platelet aggregation and lower cholesterol independent of age in aspirin-treated unstable angina: a machine learning analysis

Platelets. 2026 Dec;37(1):2743142. doi: 10.1080/09537104.2026.2743142. Epub 2026 Oct 8.ABSTRACTBACKGROUND: In aspirin-treated unstable angina (UA), heterogeneity in on-treatment arachidonic acid (AA)-induced platelet aggregation and cholesterol reduction contributes to residual ischemic risk. Insomn

J Jirao Shen

Renal Myeloid Mechanisms, Cross-Talk in Hypertension

Acta Physiol (Oxf). 2026 Nov;242(11):e70308. doi: 10.1111/apha.70308.ABSTRACTHypertension involves an impairment of renal sodium excretion along with activation of pro-inflammatory responses in the kidney. Dendritic cells (DCs) are professional antigen-presenting cells that sense disturbances in cel

L Luis Michea

EXPRESS: Association of Systemic Immune-inflammation Index and Systemic Inflammation Response Index with All-cause Mortality in the Critically Ill Population with Coronary Heart Disease and Heart Failure - A Study Based on the MIMIC-IV Database

J Investig Med. 2026 Oct 7:10815589261497360. doi: 10.1177/10815589261497360. Online ahead of print.ABSTRACTBACKGROUND: This study aimed to investigate the associations of the systemic immune-inflammation index (SII) and systemic inflammation response index (SIRI) with all-cause mortality (ACM) in c

S Siyuan Zhou