Am J Ther. 2026 Apr 9. doi: 10.1097/MJT.0000000000002136. Online ahead of print.ABSTRACTBACKGROUND: Hospital-based analyses of real-world percutaneous coronary intervention (PCI) practice remain limited.STUDY QUESTION: How do PCI strategies in non-ST-elevation acute coronary syndromes (ACSs) compare
Geroscience. 2026 Apr 8. doi: 10.1007/s11357-026-02225-8. Online ahead of print.ABSTRACTAlbuminuria is traditionally defined using fixed urinary albumin-creatinine ratio (UACR) thresholds, although cardiovascular disease (CVD) risk has been reported to increase continuously across the UACR spectrum.
Nat Genet. 2026 Apr 8. doi: 10.1038/s41588-026-02554-6. Online ahead of print.ABSTRACTGenetic variants in RNU4-2, which is transcribed into the U4 small nuclear RNA component of the major spliceosome, were recently shown to cause ReNU syndrome, a prevalent dominant neurodevelopmental disorder (NDD).
Hepatol Int. 2026 Apr 8. doi: 10.1007/s12072-026-11087-3. Online ahead of print.ABSTRACTINTRODUCTION: Fontan-associated liver disease (FALD) is a progressive congestive hepatopathy that often leads to cirrhosis and hepatocellular carcinoma. Liver nodules are common in FALD; however, noninvasive pred
J Clin Sleep Med. 2026 Apr 8;22(1):52. doi: 10.1007/s44470-026-00068-w.ABSTRACTSTUDY OBJECTIVES: The impact of obstructive sleep apnea (OSA) on all-cause mortality needs further research as earlier data are inconclusive. Between 30 and 50% of patients with OSA have comorbid insomnia (COMISA), which
J Hum Hypertens. 2026 Apr 8. doi: 10.1038/s41371-026-01143-8. Online ahead of print.ABSTRACTHypertension is a leading cause of cardiovascular disease and disproportionately affects African American (AA) adults. Apparent treatment-resistant hypertension (aTRH) is highly prevalent in this population.
Basic Res Cardiol. 2026 Apr 8. doi: 10.1007/s00395-026-01176-7. Online ahead of print.ABSTRACTAtrial fibrillation (AF) is the most common sustained cardiac arrhythmia, driven by electrical and structural remodeling that promotes proarrhythmic substrates. Interindividual variability in susceptibility
J Expo Sci Environ Epidemiol. 2026 Apr 8. doi: 10.1038/s41370-026-00890-7. Online ahead of print.ABSTRACTBACKGROUND: Extreme rainfall is expected to intensify with climate change, yet short-term health effects can plausibly be harmful (flooding, contamination, access disruption) or protective (pollu
Transl Psychiatry. 2026 Apr 8. doi: 10.1038/s41398-026-04027-0. Online ahead of print.ABSTRACTLate-onset Alzheimer's disease (LOAD) is the most common form of dementia in the elderly, yet no curative treatments are available. Although genome-wide association studies (GWASs) have identified numerous
Microsyst Nanoeng. 2026 Apr 9;12(1):126. doi: 10.1038/s41378-026-01242-z.ABSTRACTContinuous and accurate blood pressure monitoring is vital for the diagnosis and management of life-threatening cardiovascular diseases. Conventional fluid-filled catheter systems are fundamentally constrained by distor
Light Sci Appl. 2026 Apr 8;15(1):190. doi: 10.1038/s41377-026-02275-9.ABSTRACTRapid and accessible cardiac biomarker testing is essential for the timely diagnosis and risk assessment of myocardial infarction (MI) and heart failure (HF), two interrelated conditions that frequently coexist and drive r
J Clin Lipidol. 2026 Mar 16:S1933-2874(26)00075-9. doi: 10.1016/j.jacl.2026.03.005. Online ahead of print.ABSTRACTBACKGROUND: Despite the rising prevalence of dyslipidemia in adolescents from socioeconomic and lifestyle transitions, nationally representative data on dyslipidemia and its risk factors
Ann Rheum Dis. 2026 Apr 7:S0003-4967(26)00143-3. doi: 10.1016/j.ard.2026.02.024. Online ahead of print.ABSTRACTOBJECTIVES: This study aims to perform a systematic literature review (SLR) concerning the safety of synthetic and biological disease-modifying antirheumatic drugs (DMARDs) for the 2025 upd
Clin Med Res. 2026 Mar;24(1):42-45. doi: 10.3121/cmr.2025.2016.ABSTRACTSturge-Weber syndrome (SWS) is a rare neurocutaneous syndrome characterized by facial port-wine birthmarks and associated eye and meningeal angiomatosis. Its neurological manifestations include intellectual disability, seizures,
Intern Med. 2026 Apr 7. doi: 10.2169/internalmedicine.7157-26. Online ahead of print.ABSTRACTObjective We evaluated the prognostic significance of small-bowel vascular lesions (SBVLs) by comparing the overall survival and cardiovascular disease (CVD) incidence in patients with and without SBVLs foll
Occup Environ Med. 2026 Apr 8:oemed-2025-110428. doi: 10.1136/oemed-2025-110428. Online ahead of print.ABSTRACTOBJECTIVES: This study aimed to quantify and compare survival and longevity among professional wrestlers, relative to sex-matched and age-matched referents from the US general population.ME
J Prosthodont Res. 2026 Apr 7. doi: 10.2186/jpr.JPR_D_25_00246. Online ahead of print.ABSTRACTPURPOSE: This scoping review aimed to map and summarize existing evidence on the association between dental prosthesis use and cardiovascular events, highlighting current trends, methodological heterogeneit
Am J Health Syst Pharm. 2026 Apr 7:zxag106. doi: 10.1093/ajhp/zxag106. Online ahead of print.ABSTRACTPURPOSE: The TAFA-CRUZ study evaluated the real-world effectiveness and safety of tafamidis 61 mg in patients with transthyretin amyloid cardiomyopathy (ATTR-CM) and heart failure. The primary object
Can J Cardiol. 2026 Apr;42(4):626-646. doi: 10.1016/j.cjca.2025.12.035.ABSTRACTAcute heart failure in children is a complex clinical syndrome associated with significant morbidity and mortality, often requiring intensive care management and consideration of advanced therapies. The heterogeneity in p
BMJ Open. 2026 Apr 8;16(4):e108799. doi: 10.1136/bmjopen-2025-108799.ABSTRACTINTRODUCTION: Angina with no obstructive coronary artery disease (ANOCA) affects millions and is frequently under-recognised because diagnostic pathways and risk tools predominantly target obstructive coronary artery diseas
Eur Respir Rev. 2026 Apr 8;35(180):250304. doi: 10.1183/16000617.0304-2025. Print 2026 Apr.ABSTRACTBronchopulmonary dysplasia is a hallmark respiratory complication of prematurity and remains a major health determinant of individuals born very preterm. Its impact, however, extends far beyond the neo
Eur Respir Rev. 2026 Apr 8;35(180):250254. doi: 10.1183/16000617.0254-2025. Print 2026 Apr.ABSTRACTBACKGROUND: COPD frequently coexists with cardiovascular diseases. Cardiovascular death is also a major contributor to mortality in COPD patients. Inhaled corticosteroids (ICS), as the most commonly pr
Eur Respir Rev. 2026 Apr 8;35(180):250179. doi: 10.1183/16000617.0179-2025. Print 2026 Apr.ABSTRACTBACKGROUND: Respiratory viruses, frequently detected in asthma, are associated with worse outcomes. This meta-analysis systematically quantifies the prevalence of respiratory viruses in stable and acut
Prog Cardiovasc Dis. 2026 Apr 6:S0033-0620(26)00029-0. doi: 10.1016/j.pcad.2026.03.007. Online ahead of print.ABSTRACTBACKGROUND: The association between OSA and sudden cardiac death (SCD) risk in patients with hypertrophic cardiomyopathy (HCM) is poorly defined. We hypothesized that OSA may be asso
