Anatomic versus physiologic repair in congenitally corrected transposition: a propensity-matched european multicentre study

Eur J Cardiothorac Surg. 2026 Apr 13:ezag148. doi: 10.1093/ejcts/ezag148. Online ahead of print.ABSTRACTOBJECTIVES: Patients with congenitally corrected transposition of the great arteries (ccTGA) may undergo physiologic repair, leaving the right ventricle systemic, or anatomic repair, correcting th

J Jelena Pabst Von Ohain

Biological Sex Differences in the US-CTEPH-R

Ann Am Thorac Soc. 2026 Apr 13:aaoag098. doi: 10.1093/annalsats/aaoag098. Online ahead of print.ABSTRACTRATIONALE: Biological sex underpins phenotypic differences in many cardiopulmonary conditions. In pulmonary hypertension, most studies have focused on the 'sex paradox' in pulmonary arterial hyper

M Meghan M Cirulis

European Reference Networks - a flagship activity of the EU in the field of rare and complex diseases: from 2017 to 2025

No abstractOrphanet J Rare Dis. 2026 Apr 14;21(1):149. doi: 10.1186/s13023-026-04341-2.NO ABSTRACTPMID:41981625 | DOI:10.1186/s13023-026-04341-2

H Holm Graessner

Tea intake as a dietary factor for cardiovascular health: global estimates of potentially preventable ischemic heart disease

No abstractNutr J. 2026 Apr 14. doi: 10.1186/s12937-026-01322-w. Online ahead of print.NO ABSTRACTPMID:41981570 | DOI:10.1186/s12937-026-01322-w

L Longkun Liu

Ferritin and transferrin predict common carotid intima-media thickness in females: a machine-learning informed individual participant data meta-analysis

No abstractBMC Cardiovasc Disord. 2026 Apr 14. doi: 10.1186/s12872-026-05796-8. Online ahead of print.NO ABSTRACTPMID:41981480 | DOI:10.1186/s12872-026-05796-8

A Anand Ruban Agarvas

Experimental investigation of skin tissue-derived extracellular vesicles isolated from type 2 diabetic foot ulcers in impaired wound healing

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2026 Apr 15;40(4):664-674. doi: 10.7507/1002-1892.202509067.ABSTRACTOBJECTIVE: To isolate extracellular vesicles (EVs) from the wound-edge skin tissue of type 2 diabetic foot ulcers and to investigate their effect on wound healing in mice.METHODS: Twenty 8-w

R Ronghua Li

Diabetes does not attenuate the benefit of physiology-guided complete revascularization in older patients with myocardial infarction

No abstractCardiovasc Diabetol. 2026 Apr 14. doi: 10.1186/s12933-026-03165-5. Online ahead of print.NO ABSTRACTPMID:41981421 | DOI:10.1186/s12933-026-03165-5

A Alberto Sarti

Predictors of survival and transplantation outcomes in Japanese patients with interstitial lung disease referred for lung transplantation: a retrospective single-center study

No abstractBMC Pulm Med. 2026 Apr 14. doi: 10.1186/s12890-026-04280-5. Online ahead of print.NO ABSTRACTPMID:41981397 | DOI:10.1186/s12890-026-04280-5

T Takaaki Kitayama

Lung ultrasound in children with primary ciliary dyskinesia: is it able to detect structural and functional impairments?

Eur J Pediatr. 2026 Apr 15;185(5):265. doi: 10.1007/s00431-026-06923-5.ABSTRACTPrimary ciliary dyskinesia (PCD) is a chronic disorder of mucociliary clearance that leads to recurrent respiratory infections and progressive structural lung disease. Lung ultrasound (LUS) is a radiation-free bedside ima

I Işıl Bilgiç

Prevalence of frailty and its association with quality of life in Japanese patients with Behcet's disease

Clin Rheumatol. 2026 Apr 14. doi: 10.1007/s10067-026-08125-8. Online ahead of print.ABSTRACTINTRODUCTION/OBJECTIVES: Frailty is increasingly recognized as a multidimensional clinical condition associated with impaired quality of life (QoL). However, the prevalence and clinical implications in patien

H Hideyo Tsutsui

Dynamic collaboration between mitochondria and organelles: mechanisms, functions, and disease implications

Apoptosis. 2026 Apr 14;31(4):125. doi: 10.1007/s10495-026-02338-7.ABSTRACTIn recent years, numerous studies have revealed that dysregulation of mitochondria-organelle interactions is a common feature underlying various pathological processes and pathogen infections. For instance, in Alzheimer's dise

B Bin Shao

Anti-amyloid antibody equilibrium binding to Abeta aggregates from human Alzheimer's disease brain

Alzheimers Dement. 2026 Apr;22(4):e71350. doi: 10.1002/alz.71350.ABSTRACTINTRODUCTION: Lecanemab binds "protofibrils," which are poorly characterized in human brain. It is unknown why lecanemab caused fewer amyloid-related imaging abnormalities (ARIAs) than other antibodies in trials. The apolipopro

K Katrine D Bjørnholm

mRNA medicine for cardiovascular disease

Nat Cardiovasc Res. 2026 Apr 14. doi: 10.1038/s44161-026-00804-8. Online ahead of print.ABSTRACTCardiovascular disease (CVD) remains the leading cause of global mortality, prompting urgent efforts to explore novel therapeutic approaches. The remarkable success of mRNA technology brings new possibili

Z Zhuoming Zhou

Severity and duration-dependent aortic stiffening in a rabbit coarctation model identifies constitutive material parameters as promising regional biomarkers for hypertension progression

No abstractSci Rep. 2026 Apr 14. doi: 10.1038/s41598-026-47753-7. Online ahead of print.NO ABSTRACTPMID:41981096 | DOI:10.1038/s41598-026-47753-7

A Arash Ghorbannia

Gender differences in sleep apnea: a study of the catalan population

NPJ Prim Care Respir Med. 2026 Apr 14. doi: 10.1038/s41533-026-00512-7. Online ahead of print.ABSTRACTTo analyse sex differences in the distribution and comorbidity profile of adults with diagnosed obstructive sleep apnoea (OSA) and no prior cardiovascular disease, stratified by body mass index (BMI

B Brenda Biaani León-Gómez

Sphingosine-1-Phosphate-derived 2-Hexadecenal is a central mediator of ocular neovascularization by inhibiting Sphingosine-1-Phosphate receptor 5

Nat Commun. 2026 Apr 14;17(1):3488. doi: 10.1038/s41467-026-71792-3.ABSTRACTSphingosine-1-phosphate (S1P) is a crucial sphingolipid mediator in vasculature and neovascular eye diseases by controlling angiogenesis, inflammation and fibrosis. Five S1P receptors (S1PRs) are key therapeutic targets, wit

X Xin Qian

Hi-Compass: a depth-aware deep learning framework for predicting cell-type-specific 3D genome organization from single-cell to spatial resolution

Nat Commun. 2026 Apr 14. doi: 10.1038/s41467-026-71877-z. Online ahead of print.ABSTRACTThree-dimensional genome organization controls cell-type-specific gene expression through chromatin interactions, yet systematic analysis across diverse cellular contexts remains limited by experimental constrain

Y Yuan-Chen Sun

Hypocalcemia as a nontraditional risk factor for cardiovascular events and all-cause din patients with chronic kidney disease: insights from the Korean Cohort Study for Outcomes in Patients With Chronic Kidney Disease (KNOW-CKD)

Kidney Res Clin Pract. 2026 Apr 15. doi: 10.23876/j.krcp.25.266. Online ahead of print.ABSTRACTBACKGROUND: The clinical implication of hypocalcemia is elusive in patients with chronic kidney disease (CKD). The present study aimed to investigate whether low serum calcium levels increase the risk of m

S Sang Heon Suh

Benefits of physical exercises in chronic kidney disease: a systematic review and meta-analysis of randomized controlled trials

Ren Fail. 2026 Dec;48(1):2654288. doi: 10.1080/0886022X.2026.2654288. Epub 2026 Apr 14.ABSTRACTPhysical exercise has been proven to be beneficial for chronic kidney disease (CKD) patients; however, there is a lack of a comprehensive summary of existing literature, especially the results from randomi

Y Yanqin Chen

Chronotype-aligned exercise timing in middle-aged adults at cardiometabolic risk: a randomised controlled trial

Open Heart. 2026 Apr 14;13(1):e003573. doi: 10.1136/openhrt-2025-003573.ABSTRACTOBJECTIVE: To investigate whether aligning exercise timing with chronotype enhances cardiometabolic and sleep-related benefits in sedentary adults with cardiovascular risk factors.METHODS: In this 12-week randomised cont

A Arsalan Tariq

Prognostic value of transaortic flow rate compared with ejection fraction and stroke volume index in low-gradient severe aortic stenosis

Heart. 2026 Apr 14:heartjnl-2025-327594. doi: 10.1136/heartjnl-2025-327594. Online ahead of print.ABSTRACTBACKGROUND: In low-gradient severe aortic stenosis (AS), reduced left ventricular ejection fraction (LVEF <50%) is practically used to define low flow and prompt dobutamine stress echocardiograp

M Mohamed Allam

Unlocking clinical narratives: how natural language processing and artificial intelligence can address data deficits and mitigate health inequities in urgent and emergency care

Emerg Med J. 2026 Apr 14:emermed-2025-215530. doi: 10.1136/emermed-2025-215530. Online ahead of print.ABSTRACTThe Urgent and Emergency Care system generates a wealth of clinical information, but our ability to harness this for public health planning and to address health inequalities is constrained

C Chris Humphries

Management of ruptured splenic artery aneurysm in pregnancy: a life-threatening emergency

BMJ Case Rep. 2026 Apr 14;19(4):e270137. doi: 10.1136/bcr-2025-270137.ABSTRACTSplenic artery aneurysm (SAA) rupture in pregnancy is a rare but life-threatening event. We report the case of a 30 week pregnant patient with class III obesity, who presented with circulatory collapse and vague abdominal

S Sunti Barahi

Myeloproliferative neoplasm as a cause of splanchnic vein thrombosis

BMJ Case Rep. 2026 Apr 14;19(4):e271608. doi: 10.1136/bcr-2025-271608.ABSTRACTSplanchnic vein thrombosis (SVT) is a rare, life-threatening condition that is often associated with cirrhosis, pancreatic malignancy and thrombophilia. Myeloproliferative neoplasms are under-recognised causes, posing diag

B Brian Abboud