Cardiovasc Diabetol. 2026 Jul 24;25(1):210. doi: 10.1186/s12933-026-03292-z.ABSTRACTBACKGROUND: Inhibitors of the sodium-glucose cotransporter 2 (SGLT2) provide cardiovascular and renal protection in both diabetic and non-diabetic patients at least in part independently of glycaemic control. Some un
ASN Neuro. 2026;18(1):2702948. doi: 10.1080/17590914.2026.2702948. Epub 2026 Jul 24.ABSTRACTIschemic stroke induces a plethora of pathophysiological changes, including neuroinflammation and chronic cerebrovascular dysfunction. In humans, even small, silent strokes can trigger these pathologies, whic
Disorder of the immune microenvironment plays an important role in the occurrence and development of multiple myeloma in patients. While bone marrow SUVmax on ^(18)F-FDG PET/CT correlates with MM disease characteristics, its association with the immune microenvironment remains unclear. This study an
Eur J Pediatr. 2026 Jul 25;185(8):607. doi: 10.1007/s00431-026-07274-x.ABSTRACTThe aim of this study was to assess right ventricle (RV) systolic function in infants with severe bronchiolitis using tricuspid annular plane systolic excursion (TAPSE) and to explore its prognostic value. We hypothesized
Sci Rep. 2026 Jul 24;16(1):23203. doi: 10.1038/s41598-026-61992-8.ABSTRACTImmunoglobulins (Ig) are essential for protection against invading pneumococci but are not routinely analyzed in patients with invasive pneumococcal disease (IPD). In this prospective study, we assessed the prevalence of monoc
Nat Genet. 2026 Jul 24. doi: 10.1038/s41588-026-02697-6. Online ahead of print.ABSTRACTUnderstanding genetic variation associated with differences in plasma protein levels can elucidate human disease mechanisms. Here we demonstrate how untargeted nanoparticle-enriched mass spectrometry (MS)-based pl
Br Dent J. 2026 Jul;241(2):110-115. doi: 10.1038/s41415-026-9788-2. Epub 2026 Jul 24.ABSTRACTHereditary angioedema is a rare genetic disorder causing recurrent, potentially life-threatening swelling episodes, often triggered by dental procedures. Swellings resemble anaphylaxis, but pathophysiology a
Nat Med. 2026 Jul 24. doi: 10.1038/s41591-026-04496-2. Online ahead of print.ABSTRACTThere is a need for robust evaluations of noninvasive biomarkers for metabolic dysfunction-associated steatotic liver disease. This prospective multicenter study assessed the diagnostic accuracy of imaging (includin
Br J Pharmacol. 2026 Jul 24. doi: 10.1111/bph.70608. Online ahead of print.ABSTRACTBACKGROUND AND PURPOSE: Anthracyclines such as doxorubicin (DOXO) remain a cornerstone of cancer therapy but are associated with a high risk of cardiotoxicity and subsequent heart failure (HF). Impairment of NO/solubl
J Cardiothorac Vasc Anesth. 2026 Jul 4:S1053-0770(26)00561-6. doi: 10.1053/j.jvca.2026.07.004. Online ahead of print.ABSTRACTOBJECTIVES: Cesarean delivery in women with Fontan circulation poses significant risks of hemodynamic instability. We aimed to characterize perioperative hemodynamic fluctuati
BMJ Open. 2026 Jul 24;16(7):e120259. doi: 10.1136/bmjopen-2026-120259.ABSTRACTBACKGROUND: Diabetes complicated by cardiovascular diseases and chronic kidney diseases poses a growing global burden. Sodium-glucose co-transporter-2 (SGLT-2) inhibitors and glucagon-like peptide-1 receptor agonists (GLP-
BMJ Open. 2026 Jul 24;16(7):e116166. doi: 10.1136/bmjopen-2025-116166.ABSTRACTOBJECTIVES: To determine the time to major adverse cardiovascular events (MACE) and identify its predictors among patients with acute coronary syndrome (ACS) discharged on secondary prevention medications in Ethiopia.DESIG
Med Clin North Am. 2026 Sep;110(5):963-978. doi: 10.1016/j.mcna.2026.01.006. Epub 2026 Feb 26.ABSTRACTThe reported prevalence of sleep disorders in the dental population ranges between 15% and 60%. Sleep has been known to have a bidirectional relationship with systemic diseases. There has been a ste
Med Clin North Am. 2026 Sep;110(5):923-936. doi: 10.1016/j.mcna.2026.01.003. Epub 2026 Feb 18.ABSTRACTSudden unexpected death during sleep particular in young people often provokes remorse whether could it have been prevented. Often the presenting symptom of sudden unexpected nocturnal death is deat
Med Clin North Am. 2026 Sep;110(5):771-788. doi: 10.1016/j.mcna.2025.12.003. Epub 2026 Apr 21.ABSTRACTThe impact of sleep on health has been the topic of recent research. Numerous systemic conditions and diseases may have a significant impact on sleep, and vice versa. There are complex interrelation
Fine particulate matter (PM(2.5)) remains to be the leading cause of global disease burden and is linked to arterial calcification in humans. This study revealed that PM(2.5) facilitated the phenotype switching of mouse aortic smooth muscle (MOVAS) cells and promoted in vitro calcification in the pr
Int J Sports Med. 2026 Jul 24. doi: 10.1055/a-2896-9042. Online ahead of print.ABSTRACTAmenorrhea in female athletes may be associated with cardiovascular disease risk factors. We aimed to implement a rigorous methodology to confirm menstrual status and examine differences in lipid and inflammatory
Semin Neurol. 2026 Aug;46(4):367-373. doi: 10.1055/a-2893-7436. Epub 2026 Jul 24.ABSTRACTNon-stenotic carotid disease represents an understudied yet clinically significant pathology. While stenosis is the primary mechanism underlying most strokes, other mechanisms such as thromboembolism from plaque
Eur J Pharmacol. 2026 Jul 24:179177. doi: 10.1016/j.ejphar.2026.179177. Online ahead of print.ABSTRACTThe pyripyropenes A-X represent a family of 24 alkaloids isolated from fungi, mainly Aspergillus and Penicillium species, over the past 30 years. Numerous analogues have been isolated from fungi or
Life Sci. 2026 Jul 24:124598. doi: 10.1016/j.lfs.2026.124598. Online ahead of print.ABSTRACTBACKGROUND: While the pro-inflammatory M4 macrophage phenotype contributes to cardiovascular pathogenesis, its specific involvement in chronic post myocardial infarction (MI) remodeling and responsiveness to
Clin Nutr ESPEN. 2026 Jul 24:103614. doi: 10.1016/j.clnesp.2026.103614. Online ahead of print.ABSTRACTChronic intestinal failure (CIF) is characterized by loss of intestinal absorptive capacity and requires home parenteral nutrition (HPN). This condition significantly impacts homeostasis, quality of
Biochem Pharmacol. 2026 Jul 24:118290. doi: 10.1016/j.bcp.2026.118290. Online ahead of print.ABSTRACTCells and tissues are continuously exposed to mechanical cues from their surrounding microenvironment. Mechanobiology investigates how these cues are converted into intracellular biochemical and tran
The transient receptor potential vanilloid 2 (TRPV2) channel is a Ca^(2+)-permeable non-selective cation channel widely expressed in immune cells, cardiomyocytes, neurons, and various cancers. It participates in diverse physiological and pathological processes, including neuronal differentiation, me
J Am Pharm Assoc (2003). 2026 Jul 24:103491. doi: 10.1016/j.japh.2026.103491. Online ahead of print.ABSTRACTBACKGROUND: Transgender and gender-diverse (TGD) individuals may experience physiologic changes from gender-affirming hormone therapy (GAHT) that complicate clinical calculations with binary s
