Trends Endocrinol Metab. 2026 Mar 26:S1043-2760(26)00006-8. doi: 10.1016/j.tem.2026.01.006. Online ahead of print.ABSTRACTObesity and (white) adipose tissue (AT) inflammation are closely linked to endothelial dysfunction (ED) and neurological conditions associated with an impaired blood-brain barrie
Am J Geriatr Psychiatry. 2026 Mar 6:S1064-7481(26)00095-3. doi: 10.1016/j.jagp.2026.02.015. Online ahead of print.ABSTRACTOBJECTIVE: Affective neuropsychiatric symptoms (NPS)-depression, anxiety, and apathy-are frequent in older adults. Understanding which clinical characteristics might be associate
Handb Clin Neurol. 2026;216:59-73. doi: 10.1016/B978-0-443-15736-3.00014-7.ABSTRACTThe regulation of systemic arterial blood pressure is key to survival. The sympathetic and parasympathetic regulation of arterial blood pressure requires information related to the actual blood pressure values for fee
Handb Clin Neurol. 2026;216:213-236. doi: 10.1016/B978-0-443-15736-3.00011-1.ABSTRACTThe brainstem is a heterogeneous assembly of well-organized nuclei and pathways that play a critical role in motor, sensory, arousal, and autonomic functions. Because of its extensive reciprocal connections with the
Food Res Int. 2026 May 31;232:118847. doi: 10.1016/j.foodres.2026.118847. Epub 2026 Mar 8.ABSTRACTThrombotic diseases are the primary cause of cardiovascular diseases. Existing clinical drugs are associated with side effects such as bleeding and gastrointestinal damage, making the development of saf
No abstractHeart Fail Clin. 2026 Apr;22(2):xi-xiii. doi: 10.1016/j.hfc.2026.01.001. Epub 2026 Feb 13.NO ABSTRACTPMID:41895901 | DOI:10.1016/j.hfc.2026.01.001
Heart Fail Clin. 2026 Apr;22(2):243-260. doi: 10.1016/j.hfc.2025.11.005.ABSTRACTDiagnosis and treatment of cardiac amyloidosis have rapidly evolved over the past decade by harnessing mechanisms of disease pathogenesis. Cardiac amyloidosis is caused by myocardial deposition of fibrils formed by misfo
Heart Fail Clin. 2026 Apr;22(2):237-242. doi: 10.1016/j.hfc.2025.11.006.ABSTRACTAdults with congenital heart disease make up most patients with congenital heart disease vastly surpassing the pediatric patients largely because of significant improvements in the medical, interventional, and surgical a
Heart Fail Clin. 2026 Apr;22(2):221-235. doi: 10.1016/j.hfc.2025.12.001.ABSTRACTThe diagnosis and management of hypertrophic cardiomyopathy (HCM) requires accurate and comprehensive imaging. Advances in imaging technology and clinical understanding have significantly enhanced the ability to characte
Heart Fail Clin. 2026 Apr;22(2):209-220. doi: 10.1016/j.hfc.2025.12.004. Epub 2026 Feb 13.ABSTRACTSecondary mitral regurgitation (MR) is a common and prognostically important complication of heart failure that results from adverse ventricular remodeling rather than intrinsic valve pathology. While o
Heart Fail Clin. 2026 Apr;22(2):193-207. doi: 10.1016/j.hfc.2025.11.004. Epub 2025 Dec 9.ABSTRACTThe prevalence of cardiogenic shock (CS) has continued to rise over the past 2 decades. The management of this disease process is extensive, involving pharmacologic support, mechanical ventilation, renal
Heart Fail Clin. 2026 Apr;22(2):183-191. doi: 10.1016/j.hfc.2025.12.003.ABSTRACTAlthough women and men have similar lifetime risks and mortality related to heart failure (HF), women have a greater risk of developing heart failure with preserved ejection fraction (HFpEF) versus developing heart failu
Heart Fail Clin. 2026 Apr;22(2):163-182. doi: 10.1016/j.hfc.2025.12.002.ABSTRACTChronic or severe ischemic heart disease can lead to damaged or infarcted myocardium that can progress to heart failure. When evaluating revascularization, one should consider noninvasive assessments, physiologic testing
Heart Fail Clin. 2026 Apr;22(2):149-162. doi: 10.1016/j.hfc.2025.11.003. Epub 2025 Dec 22.ABSTRACTVentricular arrhythmia remains a challenge in the heart failure population, resulting in significant morbidity and mortality despite modern heart failure therapies. Patients with heart failure who have
Heart Fail Clin. 2026 Apr;22(2):133-147. doi: 10.1016/j.hfc.2025.11.002. Epub 2026 Jan 28.ABSTRACTIn this review, we provide a detailed up-to-date summary of hypertrophic cardiomyopathy (HCM). From the complex and diverse presentations to the individualized clinical profiles, we delve into the diffe
Heart Fail Clin. 2026 Apr;22(2):119-131. doi: 10.1016/j.hfc.2025.11.001. Epub 2025 Dec 15.ABSTRACTAdvanced heart failure is characterized by persistent severe symptoms and functional limitations despite optimal medical therapy and carries significant morbidity and mortality. This article discusses t
Emerg Med Clin North Am. 2026 May;44(2):365-379. doi: 10.1016/j.emc.2025.11.002. Epub 2026 Jan 23.ABSTRACTStroke is one of the leading causes of adult disability. Missed stroke diagnoses increase morbidity and mortality and can result from a variety of factors. Thrombolytic therapy in stroke mimics
Emerg Med Clin North Am. 2026 May;44(2):315-331. doi: 10.1016/j.emc.2025.09.003. Epub 2026 Feb 20.ABSTRACTIn patients with shock, early recognition and timely initiation of appropriate management critically impacts patient outcomes. Currently prevalent approaches to shock in the emergency department
Emerg Med Clin North Am. 2026 May;44(2):309-314. doi: 10.1016/j.emc.2026.01.001.ABSTRACTTachycardia is among the most common abnormalities encountered in emergency department (ED) patients and simultaneously one of the most frequently underappreciated. Although often attributed to benign or physiolo
Emerg Med Clin North Am. 2026 May;44(2):289-307. doi: 10.1016/j.emc.2025.12.001. Epub 2026 Feb 20.ABSTRACTBradycardia has a broad differential, which can be narrowed by history, physical examination, and electrocardiogram. Symptomatic cases often stem from sick sinus syndrome or atrioventricular blo
Emerg Med Clin North Am. 2026 May;44(2):265-277. doi: 10.1016/j.emc.2025.09.002. Epub 2025 Nov 7.ABSTRACTAcute limb ischemia (ALI) and compartment syndrome (CS) are pathologies that can be difficult to identify but have devastating outcomes if not diagnosed in a timely manner. ALI can be missed if t
Emerg Med Clin North Am. 2026 May;44(2):249-263. doi: 10.1016/j.emc.2025.09.001. Epub 2026 Feb 19.ABSTRACTAcute mesenteric ischemia (AMI) presents variably based on etiology-arterial embolism (often from atrial fibrillation), arterial thrombosis (due to atherosclerosis), mesenteric venous thrombosis
Thorax. 2026 Mar 27:thorax-2025-224120. doi: 10.1136/thorax-2025-224120. Online ahead of print.ABSTRACTElevated troponin I (TnI) has been reported in patients with chronic obstructive pulmonary disease (COPD) without cardiovascular disease (CVD), suggesting non-ischaemic mechanisms. We assessed this
Asia Pac J Clin Nutr. 2026 Apr;35(2):347-359. doi: 10.6133/apjcn.202604_35(2).0013.ABSTRACTBACKGROUND AND OBJECTIVES: Globally, efforts are underway to evaluate foods and meals by their nutritional value. In Japan, however, there is no comprehensive system for evaluating overall diet quality. The ai
