An integrated investigation of systemic and localized pathophysiological mechanisms of stroke and multimodal therapeutic strategies

Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2026 Jul 28;51(7):1530-1553. doi: 10.11817/j.issn.1672-7347.2026.260153.ABSTRACTStroke can trigger complex systemic pathophysiological responses. By systematically reviewing the pathophysiological mechanisms following stroke and comprehensive intervention strateg

Q Qian Liu

Effects of a lung recruitment maneuver combined with individualized positive end-expiratory pressure on postoperative pulmonary complications and perioperative hemodynamics in hypertensive patients undergoing pulmonary resection

Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2026 Jul 28;51(7):1438-1448. doi: 10.11817/j.issn.1672-7347.2026.260205.ABSTRACTOBJECTIVES: A lung recruitment maneuver (LRM) combined with a dynamic lung compliance-guided positive end-expiratory pressure (PEEP) strategy can reduce the risk of postoperative pulm

K Kechen Shi

Association between dietary folic acid intake and diabetic retinopathy among patients with diabetes: An analysis of 2005-2008 NHANES data

Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2026 Jul 28;51(7):1426-1437. doi: 10.11817/j.issn.1672-7347.2026.250359.ABSTRACTOBJECTIVES: Dietary folic acid (FA) intake may reduce homocysteine levels and alleviate oxidative stress, both of which are closely associated with the development and progression of

Z Zidi Meng

Environmental relative humidity, frailty, and risk of incident stroke among middle-aged and older adults in China: A prospective cohort study

Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2026 Jul 28;51(7):1411-1425. doi: 10.11817/j.issn.1672-7347.2026.260128.ABSTRACTOBJECTIVES: Stroke is one of the leading causes of death and disability in China and imposes a substantial disease burden. Population aging has further increased the challenges of str

Y Yangbo Zhou

Association of wearable-device-measured fragmented sedentary behavior with cardiovascular disease, mortality, and life expectancy

Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2026 Jul 28;51(7):1392-1410. doi: 10.11817/j.issn.1672-7347.2026.260193.ABSTRACTOBJECTIVES: It remains unclear whether the degree of fragmentation modifies the adverse health outcomes associated with prolonged sedentary behavior. This study aims to investigate th

T Tianhua Xing

Corrigendum to "CSF-1 promotes microglial proliferation and ameliorates ischemic brain injury" [Neurochem. Int. 199, (2026), 106233]

No abstractNeurochem Int. 2026 Sep 19:106259. doi: 10.1016/j.neuint.2026.106259. Online ahead of print.NO ABSTRACTPMID:42763286 | DOI:10.1016/j.neuint.2026.106259

S Shiji Deng

Platelet glycoprotein VI in platelet-neutrophil interactions: From complex formation to neutrophil extracellular trap-associated pathology

Int Immunopharmacol. 2026 Sep 19:117439. doi: 10.1016/j.intimp.2026.117439. Online ahead of print.ABSTRACTPlatelets and neutrophils form dynamic platelet-neutrophil complexes (PNCs) that connect vascular injury with inflammatory effector responses. Glycoprotein VI (GPVI), a platelet-restricted immun

W Wei-Chen Xiong

Steatotic liver disease phenotypes and cardiac autonomic dysfunction: a community-based study in China

Nutr Metab Cardiovasc Dis. 2026 Sep 19:104869. doi: 10.1016/j.numecd.2026.104869. Online ahead of print.ABSTRACTBACKGROUND AND AIMS: Steatotic liver disease (SLD) is increasingly recognized as a systemic disorder linked to cardiometabolic risk. Cardiac autonomic dysfunction may represent an early me

B Bo Liu

Association of lipoprotein(a) and MASLD in predicting carotid atherosclerosis in asymptomatic individuals: a large scale cross-sectional and longitudinal study

Nutr Metab Cardiovasc Dis. 2026 Jun 23:104850. doi: 10.1016/j.numecd.2026.104850. Online ahead of print.ABSTRACTBACKGROUND AND AIM: This study investigated the associations of Lipoprotein (a) [Lp(a)] and metabolic dysfunction-associated steatotic liver disease (MASLD) with carotid atherosclerosis (C

W Wen Guo

Mechanism of GRK2-mediated AdipoR1 Ser205 phosphorylation in myocardial injury in diabetic mice and the cardioprotective effect of site-directed mutagenesis

Zhonghua Yi Xue Za Zhi. 2026 Sep 22;106(35):3772-3781. doi: 10.3760/cma.j.cn112137-20260508-01227.ABSTRACTObjective: To explore the role and mechanism of G-protein coupled receptor kinase 2 (GRK2)-mediated phosphorylation of adiponectin receptor 1 (AdipoR1) in diabetic cardiomyopathy (DCM), and to v

Z Z J Yang

Analysis of related factors for the occurrence of cardiovascular-renal-metabolic syndrome stage 4 in patients with primary aldosteronism

Zhonghua Yi Xue Za Zhi. 2026 Sep 22;106(35):3764-3771. doi: 10.3760/cma.j.cn112137-20260408-00949.ABSTRACTObjective: To explore the related factors of patients with primary aldosteronism (PA) developing into stage 4 of cardiovascular-renal-metabolic syndrome (CKM). Methods: A total of 397 patients d

M M X Yang

Analysis of influencing factors and construction of a predictive model for cardiovascular autonomic neuropathy in type 2 diabetes mellitus

Zhonghua Yi Xue Za Zhi. 2026 Sep 22;106(35):3754-3763. doi: 10.3760/cma.j.cn112137-20260410-00979.ABSTRACTObjective: To investigate the influencing factors for cardiovascular autonomic neuropathy (CAN) in patients with type 2 diabetes mellitus (T2DM) and to develop a predictive model. Methods: A ret

Y Y L Jiang

Development history of the Diabetes Foot and Peripheral Vascular Disease Group of the Chinese Medical Association Chinese Diabetes Society: a review and prospect

Zhonghua Yi Xue Za Zhi. 2026 Sep 22;106(35):3665-3673. doi: 10.3760/cma.j.cn112137-20260709-01728.ABSTRACTThe Diabetic Foot Group of the Chinese Diabetes Society, Chinese Medical Association was founded in 1995 and renamed the Diabetes Foot and Peripheral Vascular Disease Group (hereinafter referred

Z Z R Xu

Analysis of incidence characteristics and influencing factors of metabolic syndrome among rural residents in Southern Xinjiang Uygur Autonomous Region

Zhonghua Liu Xing Bing Xue Za Zhi. 2026 Sep 10;47(9):1612-1619. doi: 10.3760/cma.j.cn112338-20260105-00010.ABSTRACTObjective: To investigate the incidence characteristics and influencing factors of metabolic syndrome (MS) among rural residents in southern Xinjiang Uygur Autonomous Region, to provide

S S J Gu

Depressive symptoms and the risk for cardiovascular diseases, cancer, and chronic obstructive pulmonary disease: a prospective cohort study

Zhonghua Liu Xing Bing Xue Za Zhi. 2026 Sep 10;47(9):1604-1611. doi: 10.3760/cma.j.cn112338-20251224-00923.ABSTRACTObjective: To investigate the association of depressive symptoms with the incidence of cardiovascular disease (CVD), cancer, and chronic obstructive pulmonary disease (COPD). Methods: B

X X Wu

Association between novel high-density lipoprotein cholesterol metabolic phenotypes and all-cause and cardiovascular disease mortality in older adults in communities in Beijing

Zhonghua Liu Xing Bing Xue Za Zhi. 2026 Sep 10;47(9):1593-1603. doi: 10.3760/cma.j.cn112338-20260108-00022.ABSTRACTObjective: To investigate the association of novel high-density lipoprotein cholesterol (HDL-C) metabolic phenotypes-metabolic HDL-C (mHDL-C) and its residual (mHDL-CΔ)-with all-cause a

X X X Ye

Joint effects of short term exposure to heat and ozone on circulatory disease mortality in Beijing-Tianjin-Hebei region and surrounding areas

Objective: To examine the independent and joint effects of short-term exposure to high temperature and ozone (O(3)) on mortality from circulatory diseases and its subcategories in Beijing-Tianjin-Hebei region and surrounding areas. Methods: Daily mortality data of circulatory diseases, O(3) concentr

J J N Li

High BMI-attributable burden of eight diseases relevant to the CKM framework in China: GBD 2023 estimates and projections to 2050

Exp Gerontol. 2026 Sep 19:113331. doi: 10.1016/j.exger.2026.113331. Online ahead of print.ABSTRACTBACKGROUND: Cardiovascular-kidney-metabolic (CKM) syndrome is a recently defined clinical entity integrating metabolic risk factors, chronic kidney disease, and cardiovascular disease. Elevated body mas

J Jia Li

Clinical utility of the lipemic index for identifying severe triglyceride-rich lipoprotein disorders in adults undergoing routine blood testing

Clin Chim Acta. 2026 Sep 19:121351. doi: 10.1016/j.cca.2026.121351. Online ahead of print.ABSTRACTBACKGROUND: The lipemic index (L-index) is an automated measure of plasma turbidity used for pre-analytical quality control in clinical chemistry. As turbidity often reflects accumulation of triglycerid

P Pauline C E Schuitema

Spanish founder variant in MYBPC3: implications of diagnostic criteria, clinical phenotype, and prognosis

Rev Esp Cardiol (Engl Ed). 2026 Sep 19:S1885-5857(26)00210-0. doi: 10.1016/j.rec.2026.08.009. Online ahead of print.ABSTRACTINTRODUCTION AND OBJECTIVES: MYBPC3 is the most frequently mutated gene in hypertrophic cardiomyopathy (HCM). This study presents the clinical phenotype of a founder variant in

A Angel Júdez-Serrano

Bisdemethoxycurcumin Alleviates Myocardial Ischemia/Reperfusion Injury by AMPK-mediated Autophagy Activation and Apoptosis Suppression

Eur J Pharmacol. 2026 Sep 19:179353. doi: 10.1016/j.ejphar.2026.179353. Online ahead of print.ABSTRACTMyocardial ischemia/reperfusion (I/R) injury impairs the prognosis of patients with cardiovascular disease. Reperfusion induces cardiomyocyte apoptosis and dysregulates autophagy, thereby disrupting

L Limin Liu

Venous Thrombosis and Air Pollution: A Systematic Review and Meta-Analysis of 1.4 Million Adult Patients

J Thromb Haemost. 2026 Sep 19:S1538-7836(26)00610-0. doi: 10.1016/j.jtha.2026.09.022. Online ahead of print.ABSTRACTBACKGROUND: The comprehensive relation between air pollutants and venous thrombosis is currently not available.METHODS AND RESULTS: The Web of Science, PubMed, Scopus, and Embase datab

Y Yan Fang

The association between the Global Diet Quality Score and all-cause mortality in Black South African adults

J Nutr. 2026 Sep 19:101842. doi: 10.1016/j.tjnut.2026.101842. Online ahead of print.ABSTRACTBACKGROUND: Modifiable risk factors for cardiovascular diseases (CVD) include diet quality. The Global Diet Quality Score (GDQS) was designed to provide a comprehensive diet quality assessment, yet very few s

A Arole Shivambu

ApoE deficiency in mice exacerbates antigen-induced arthritis, alters HDL anti-oxidant capacity and promotes macrophage activation which are reversed by simvastatin treatment

Biochim Biophys Acta Mol Cell Biol Lipids. 2026 Sep 19:159771. doi: 10.1016/j.bbalip.2026.159771. Online ahead of print.ABSTRACTRheumatoid arthritis (RA) is characterized by inflammation and an increased risk for cardiovascular disease. Although it is known that metabolic disturbances alter macropha

A Asimina Kakale