Cologne (Germany): Institute for Quality and Efficiency in Health Care (IQWiG); 2026 Feb 22.ABSTRACTRESEARCH QUESTION: The aim of this report is toassess the benefit of diagnostics using cardiac magnetic resonance imaging as part of a diagnostic strategy, compared with a diagnostic strategy without
Cornea. 2026 Feb 2. doi: 10.1097/ICO.0000000000004115. Online ahead of print.ABSTRACTPURPOSE: To identify clinical factors influencing corneal endothelial damage during international transportation by evaluating the condition of donor corneas upon arrival in Japan, representing the real-world scenar
Drug Dev Res. 2026 Apr;87(2):e70247. doi: 10.1002/ddr.70247.ABSTRACTIschemic stroke is the third leading cause of death and disability worldwide. Cerebral ischemia-reperfusion injury leads to severe neuroinflammation, in which microglial polarization plays a key role. Dehydrocorydaline (DHC), the ma
JAMA Netw Open. 2026 Feb 2;9(2):e2556117. doi: 10.1001/jamanetworkopen.2025.56117.ABSTRACTIMPORTANCE: The ongoing consequences of settler colonialism produce adverse structural drivers, particularly nutrition insecurity, that contribute to cardiovascular health disparities among Indigenous populatio
JAMA Netw Open. 2026 Feb 2;9(2):e2557922. doi: 10.1001/jamanetworkopen.2025.57922.ABSTRACTIMPORTANCE: With the availability of multiple classes of advanced therapies for the treatment of Crohn disease (CD), understanding the comparative safety of different therapies can inform treatment positioning.
J Gen Physiol. 2026 Mar 2;158(2):e202513873. doi: 10.1085/jgp.202513873. Epub 2026 Feb 6.ABSTRACTThe regulation of the hyperpolarization-activated cyclic nucleotide-gated 4 (HCN4) channels in pacemaker myocytes is essential for maintaining physiological cardiac rhythm. HCN4 dysfunctional behavior is
J Cardiovasc Transl Res. 2026 Feb 6;19(1):21. doi: 10.1007/s12265-025-10719-7.ABSTRACTIntraosseous access, the fastest access in emergencies, is exclusively used for delivering medications or fluids. The correlation between intraosseous and arterial pressures remains unclear. This study aimed to exp
Mol Neurobiol. 2026 Feb 6;63(1):423. doi: 10.1007/s12035-026-05705-2.ABSTRACTThis study aimed to explore the effects of AS-252424, a selective acyl-CoA synthetase long-chain family member 4 (ACSL4) inhibitor, against retinal ischemia-reperfusion (IR) injury and to elucidate the underlying mechanisms
Neuromolecular Med. 2026 Feb 6;28(1):9. doi: 10.1007/s12017-026-08910-3.ABSTRACTChronic cerebral hypoperfusion (CCH) is a key pathological hallmark observable in multiple subtypes of cerebral small vessel disease (CSVD). This condition causes both structural and functional changes within the brain's
Eur J Clin Pharmacol. 2026 Feb 6;82(3):70. doi: 10.1007/s00228-026-03997-w.ABSTRACTBACKGROUND: Warfarin remains one of the most widely used anticoagulants; however, its narrow therapeutic index means that even small dosing deviations can result in thromboembolic or bleeding events, necessitating clo
Radiologie (Heidelb). 2026 Feb 6. doi: 10.1007/s00117-026-01574-x. Online ahead of print.ABSTRACTThe imaging-based assessment of response to treatment is essential for treatment planning and outcome prediction in oncology. Standardized classification systems enable reproducible follow-up assessments
Neuroradiology. 2026 Feb 6. doi: 10.1007/s00234-026-03913-0. Online ahead of print.ABSTRACTPURPOSE: To evaluate the associations between computer-aided multi-parametric tortuosity indexes and the occurrence and instability of intracranial aneurysms (IAs), and to explore the independence of these ass
No abstractRheumatology (Oxford). 2026 Feb 6:keag075. doi: 10.1093/rheumatology/keag075. Online ahead of print.NO ABSTRACTPMID:41649459 | DOI:10.1093/rheumatology/keag075
J Adolesc Health. 2026 Feb 6:S1054-139X(25)00813-4. doi: 10.1016/j.jadohealth.2025.11.023. Online ahead of print.ABSTRACTPURPOSE: The Global Burden of Disease (GBD) study is instrumental in understanding the global distribution and impact of diseases. Accurate estimation of type 1 diabetes mellitus
JACC Clin Electrophysiol. 2026 Feb 3:S2405-500X(25)01107-7. doi: 10.1016/j.jacep.2025.12.030. Online ahead of print.ABSTRACTBACKGROUND: Despite a common rhythm control strategy, use and safety of atrial fibrillation (AF) ablation pursued urgently among inpatients has not been adequately characterize
Int Forum Allergy Rhinol. 2026 Feb 6. doi: 10.1002/alr.70111. Online ahead of print.ABSTRACTBACKGROUND: Post hoc analyses of clinical trials have characterized dupilumab's adverse effects, yet the real-world impact in chronic rhinosinusitis with nasal polyps (CRSwNP) and asthma is not well described
J Biomed Mater Res B Appl Biomater. 2026 Feb;114(2):e70030. doi: 10.1002/jbmb.70030.ABSTRACTCurrently available in vitro benchtop aneurysm models often lack material characteristics for testing the efficacy of endovascular devices. Specifically, current models do not represent the mechanical instabi
Mol Pharm. 2026 Feb 6. doi: 10.1021/acs.molpharmaceut.5c01434. Online ahead of print.ABSTRACTAtherosclerotic cardiovascular disease (ASCVD) poses a severe threat to human health, and the global prevalence of atherosclerosis-related diseases continues to rise, necessitating urgent exploration of nove
Sex Med Rev. 2026 Jan 2;14(1):qeag001. doi: 10.1093/sxmrev/qeag001.ABSTRACTINTRODUCTION: Erectile dysfunction (ED) is a prevalent condition commonly seen by urologists, significantly affecting the sexual health of many patients. Although phosphodiesterase-5 inhibitors (PDE5Is) remain the only FDA-ap
Age Ageing. 2026 Feb 1;55(2):afag018. doi: 10.1093/ageing/afag018.ABSTRACTBACKGROUND: Consistent antihypertensive treatment reduces cardiovascular risk, but older adults requiring long-term care (LTC) due to functional impairment may have a diminished ability to adhere to treatment.OBJECTIVE: To exa
FASEB J. 2026 Feb 15;40(3):e71532. doi: 10.1096/fj.202503974R.ABSTRACTThe cardiac burden associated with doxorubicin (DOX) significantly limits its application in cancer treatment. Therefore, it is essential to identify effective strategies to protect the heart from cardiotoxic damage caused by chem
J Assoc Nurses AIDS Care. 2026 Feb 5. doi: 10.1097/JNC.0000000000000625. Online ahead of print.ABSTRACTAgreement among available cardiovascular disease (CVD) prediction models in people living with HIV (PLWH) remains unclear. This study evaluated the agreement of commonly used 10-year CVD prediction
J Med Virol. 2026 Feb;98(2):e70829. doi: 10.1002/jmv.70829.ABSTRACTTenofovir alafenamide (TAF) exhibits antiviral efficacy comparable to tenofovir disoproxil fumarate (TDF). Nonetheless, concerns persist regarding TAF's impact on the lipid profile and potential atherosclerotic cardiovascular disease
Am J Hum Biol. 2026 Feb;38(2):e70205. doi: 10.1002/ajhb.70205.ABSTRACTOBJECTIVES: Dysregulations of the hypothalamic-pituitary-adrenal (HPA) axis have been linked to adverse health outcomes such as obesity, cardiovascular disease, and diabetes. While research on the HPA axis is growing, few studies
