Normothermic Machine Perfusion Preserves Endothelial Clearance, Modulates Inflammation After Prolonged Warm Ischemia in Liver Grafts

Transplantation. 2026 Aug 1;110(8):e1629-e1637. doi: 10.1097/TP.0000000000005759. Epub 2026 Jun 30.ABSTRACTBACKGROUND: Prolonged warm ischemia time (WIT) increases susceptibility to ischemia-reperfusion injury in liver grafts. Viability assessment during normothermic machine perfusion (NMP) mainly t

A Anmar T Numan

Single-cell analysis of the progeria arterial wall reveals progerin-induced progressive, cell type-specific dysfunction and somatic mutation accumulation

Genome Med. 2026 Jul 31;18(1):115. doi: 10.1186/s13073-026-01719-6.ABSTRACTBACKGROUND: The premature aging disorder Hutchinson-Gilford Progeria Syndrome (HGPS) is caused by de novo LMNA mutations producing the aberrant Lamin A isoform progerin. HGPS patients die from cardiovascular disease, with the

L Lara G Merino

Co-managing the double burden: strategies for simultaneously tackling infectious and non-communicable diseases

Infect Dis Poverty. 2026 Jul 31;15(1):85. doi: 10.1186/s40249-026-01477-y.ABSTRACTBACKGROUND: Evidence increasingly shows close, bidirectional links between infectious diseases (IDs) and non-communicable diseases (NCDs). However, research, health policy, and prevention practices still largely addres

J Jiao-Jiao Li

Tirzepatide in recurrent hypertriglyceridemia-mediated pancreatitis and type 2 diabetes: a case report

Cardiovasc Diabetol Endocrinol Rep. 2026 Aug 1;12(1):50. doi: 10.1186/s40842-026-00318-z.ABSTRACTBACKGROUND: Hypertriglyceridemia‑mediated acute pancreatitis (HTG‑AP) is a clinically relevant complication of severe metabolic dysfunction, yet incretin‑based therapy is often withheld because current r

B Benjamin Lechner

Effects of riociguat on right ventricular size and function in pulmonary arterial hypertension (RIVER II): a prospective, phase IV study

Respir Res. 2026 Jul 28;27(1):296. doi: 10.1186/s12931-026-03843-8.ABSTRACTBACKGROUND: Pulmonary arterial hypertension (PAH) is characterized by right ventricular (RV) pressure overload, dilatation and dysfunction, which are key prognostic determinants. While riociguat improves exercise capacity and

S Satenik Harutyunova

Select plasma oxylipins as potential biomarkers of effective indomethacin treatment response in preterm infants with patent ductus arteriosus

Metabolomics. 2026 Jul 31;22(4):136. doi: 10.1007/s11306-026-02510-9.ABSTRACTOBJECTIVES: Patent ductus arteriosus (PDA) is one of the most common heart conditions in preterm infants, and indomethacin treatment is used for PDA closure. However, its efficacy varies among patients. This pilot study aim

K Khanh C K Nguyen

Heterogeneity in the association between APOE ε4 carrier status and dementia risk by modifiable and non-modifiable risk factors

Geroscience. 2026 Jul 31. doi: 10.1007/s11357-026-02452-z. Online ahead of print.ABSTRACTDementia is a major public health challenge, and Apolipoprotein E (APOE) ε4 is strongly associated with all-cause dementia, particularly Alzheimer's disease (AD). We aim to quantify the overall contribution of m

M Mengrong Zhang

Efficacy and Safety of the Extemporaneous Combination Nebivolol/Amlodipine in Patients with Hypertension Uncontrolled on Monotherapy: The BOTTICELLI Study

High Blood Press Cardiovasc Prev. 2026 Jul 31. doi: 10.1007/s40292-026-00816-2. Online ahead of print.ABSTRACTINTRODUCTION: Hypertension is the leading cause of cardiovascular disease, and its complications are preventable with blood pressure (BP)-lowering treatment. Combination treatment with 2 or

M Massimo Volpe

Cardiovascular safety of psilocybin in psychiatric practice: a narrative review

Eur J Clin Pharmacol. 2026 Aug 1;82(8):223. doi: 10.1007/s00228-026-04151-2.ABSTRACTPURPOSE: Psilocybin-assisted interventions are moving from efficacy trials toward psychiatric implementation. Cardiovascular interpretation is central to this transition because trial participants are generally medic

L Lukasz Szarpak

Unveiling the pharmacological landscape of geniposidic acid: mechanisms of action, therapeutic benefits, and scientific challenges

Naunyn Schmiedebergs Arch Pharmacol. 2026 Aug 1. doi: 10.1007/s00210-026-05762-3. Online ahead of print.ABSTRACTGeniposidic acid (GPA) is a bioactive iridoid glycoside mainly found in many traditional medicinal plants, including Eucommia ulmoides and Gardenia jasminoides. These plants are also commo

L Lakshmi Narayana Ellutla

Cross-species functional transcriptomic analysis distinguishes conserved aging-niche remodeling from inflammatory fibroblast heterogeneity in cardiac aging and heart failure

Funct Integr Genomics. 2026 Aug 1;26(1):215. doi: 10.1007/s10142-026-02001-z.ABSTRACTCardiac aging is accompanied by inflammatory and extracellular-matrix remodeling, but the extent to which aging-associated fibroblast programs are reproducibly altered in human heart failure remains unclear. We inte

Y Yimeng Li

Hypertensive disorders of pregnancy and women's health throughout the life course: an update review 2025-2026

Hypertens Res. 2026 Jul 31. doi: 10.1038/s41440-026-02749-8. Online ahead of print.ABSTRACTDespite growing research efforts to prevent hypertensive disorders of pregnancy (HDP) and preeclampsia (PE), the global incidence of HDP continues to rise. This trend parallels the increasing prevalence of chr

M Marie Yasuda

Recent updates and perspectives in "Onco-hypertension"

Hypertens Res. 2026 Jul 31. doi: 10.1038/s41440-026-02722-5. Online ahead of print.ABSTRACTAdvances in treatments for cancer patients have markedly improved their long-term survival, leading to a growing population of cancer survivors. Consequently, hypertension and cardiovascular disease developmen

S Satoshi Kidoguchi

The functional lumen opening with self-forming magnetic anastomosis (FLOWS) study: results from the North American pivotal trial

Surg Endosc. 2026 Jul 31. doi: 10.1007/s00464-026-13211-8. Online ahead of print.ABSTRACTOBJECTIVE: To evaluate the safety and effectiveness of using self-forming magnets (SFM) with an immediately functional lumen for the creation of small bowel anastomoses.BACKGROUND: Prevention of short-, medium-,

A Andre Teixeira

Prolonged puncturing decreases ventriculoperitoneal shunt insertion rate in neonates with posthemorrhagic ventricular dilatation

Childs Nerv Syst. 2026 Aug 1;42(1):317. doi: 10.1007/s00381-026-07408-4.ABSTRACTPURPOSE: Posthemorrhagic ventricular dilatation (PHVD) is a frequent complication of intraventricular hemorrhage (IVH) in preterm infants and is associated with increased neurodevelopmental morbidity. Following national

D Dino Gačević

Spatiotemporal transcriptomics of human cardiovascular progenitors in pig hearts identifies Midkine as a positive regulator of neovascularization

Nat Cardiovasc Res. 2026 Jul 31. doi: 10.1038/s44161-026-00851-1. Online ahead of print.ABSTRACTStem-cell-based cardiac repair holds promise for the infarcted myocardium, yet the in vivo molecular behavior of transplanted cells is poorly understood. Using time series spatial transcriptomics, we prof

S Swarnaseetha Adusumalli

Shiver me timbers: cold-driven lipids fuel platelet production

No abstractCell Res. 2026 Jul 31. doi: 10.1038/s41422-026-01265-1. Online ahead of print.NO ABSTRACTPMID:42538379 | DOI:10.1038/s41422-026-01265-1

Y Yupeng Wu

Asymmetric plantar temperature downshifts are associated with atrial fibrillation and thromboembolic events: an observational post hoc analysis of the SmartPreventDiabeticFeet study

Commun Med (Lond). 2026 Jul 31;6(1):424. doi: 10.1038/s43856-026-01811-3.ABSTRACTBACKGROUND: Cardiovascular and thromboembolic complications remain a major burden in diabetes. We aimed to determine whether peripheral thermometry is suited to detect plantar temperature downshifts (PTDs). Plantar infr

A Antao Ming

Personalized Weight-Loss Targets for Metabolic Syndrome Reversal: A BMI-Normalization Achievement Rate-Based Cohort Study

Obesity (Silver Spring). 2026 Jul 31. doi: 10.1002/oby.70269. Online ahead of print.ABSTRACTOBJECTIVE: This study aimed to explore personalized weight-loss targets for metabolic syndrome (MetS) reversal by introducing the BMI-normalization achievement rate (BMI-NAR), a novel baseline-BMI-scaled metr

J Junfeng Qi

Cardiac rehabilitation referral and access by country income class: Comparisons from the International Council of Cardiovascular Prevention and Rehabilitation's 2025 Global Audit Update

Eur J Intern Med. 2026 Jul 31:107106. doi: 10.1016/j.ejim.2026.107106. Online ahead of print.ABSTRACTOBJECTIVES: To characterize CR: (1) referral practices, (2) systematic referral barriers, (3) wait listing, (4) program-level approaches to mitigating patient access barriers, as well as (5) CR reimb

R Rachael P Carson

Early Outcomes and Utilisation of Drug-Coated Balloons for Coronary Artery Revascularisation From the Victorian Cardiac Outcomes Registry

Heart Lung Circ. 2026 Jul 31:S1443-9506(26)00206-4. doi: 10.1016/j.hlc.2026.03.059. Online ahead of print.ABSTRACTBACKGROUND & AIMS: Recent trends towards a "leave nothing behind" strategy are reshaping coronary artery disease management. Drug-coated balloons (DCB) deliver an antiproliferative drug

D Davide R Tomassoni

JCL Roundtable: Rewriting the rules for primary prevention: New outcomes from intensive LDL-C reduction in high-risk patients

J Clin Lipidol. 2026 Jul 15:S1933-2874(26)00450-2. doi: 10.1016/j.jacl.2026.07.021. Online ahead of print.ABSTRACTThis Journal of Clinical Lipidology Roundtable presents a conversation between Drs Robert P. Giugliano, Nicholas A. Marston, and Kevin C. Maki, who discussed clinical trials investigatin

R Robert P Giugliano

Efficacy and safety of inclisiran monotherapy in Chinese adults with elevated low-density lipoprotein cholesterol: Results from the VICTORION-Mono China trial

J Clin Lipidol. 2026 Jun 26:S1933-2874(26)00408-3. doi: 10.1016/j.jacl.2026.06.016. Online ahead of print.ABSTRACTBACKGROUND: Atherosclerotic cardiovascular disease (ASCVD) remains the leading cause of death in China. Elevated low-density lipoprotein cholesterol (LDL-C) is a major, modifiable cardio

Y Yong Huo

Preprocedural clinical and angiographic predictors of improved cardiovascular outcomes with final two-stent implantation in coronary bifurcation lesions; the Bifurcation Two-Stent (BTS) score

Cardiovasc Revasc Med. 2026 Jul 22:S1553-8389(26)00300-3. doi: 10.1016/j.carrev.2026.07.012. Online ahead of print.ABSTRACTBACKGROUND: Provisional stenting has become the default treatment strategy for most coronary bifurcation lesions However, in some clinical and anatomical settings, final two-ste

Y Youngwoo Jang