Effect of a community-based intervention for cardiovascular risk factor control on stroke mortality in rural Gadchiroli, India: a cluster-randomised controlled trial

Wellcome Open Res. 2026 Jul 8;11:209. doi: 10.12688/wellcomeopenres.26002.2. eCollection 2026.ABSTRACTBACKGROUND: Stroke is the second leading cause of death globally. We tested whether it was feasible to deliver a community-based intervention package for prevention of stroke and, whether such an in

Y Yogeshwar Kalkonde

Prognostic value of hemoglobin-to-serum creatinine ratio in patients with coronary artery disease and reduced kidney function following percutaneous coronary intervention

Front Cardiovasc Med. 2026 Sep 10;13:1868952. doi: 10.3389/fcvm.2026.1868952. eCollection 2026.ABSTRACTOBJECTIVE: This investigation sought to assess the prognostic significance of the hemoglobin-to-serum creatinine (Hb/SCr) ratio for long-term survival among patients with coexisting coronary artery

S Sini Fang

Sociodemographic factors associated with depressive symptoms and self-care agency capacity in hypertensive older adults from Loja, Ecuador: a cross-sectional study

Front Public Health. 2026 Sep 10;14:1888008. doi: 10.3389/fpubh.2026.1888008. eCollection 2026.ABSTRACTBACKGROUND: Hypertension is one of the leading chronic diseases affecting older adults and is frequently associated with depressive symptoms and difficulties in self-care. Sociodemographic conditio

E Eddison Josué Ramírez-Merchán

Screening for inflammation and treatment with colchicine in adults with known cardiovascular disease: an analysis of 13.5 million patients

Front Med (Lausanne). 2026 Sep 10;13:1882786. doi: 10.3389/fmed.2026.1882786. eCollection 2026.ABSTRACTBACKGROUND: Identifying and treating inflammation is a recommended atherosclerotic cardiovascular disease (ASCVD) prevention strategy. The practice of screening for and treating inflammation is unk

A Arch G Mainous

Impact of left anterior descending myocardial bridges on coronary artery diameters and collateral vessel development: a retrospective coronary computed tomography angiography analysis

Folia Morphol (Warsz). 2026;85:e01726153. doi: 10.5603/fm.113929.ABSTRACTBACKGROUND: A myocardial bridge (MB) is a congenital coronary anomaly most commonly located in the mid-segment of the left anterior descending coronary artery (LAD). This study aimed to evaluate the impact of mid-LAD myocardial

A Ahmet S Çil

Dietary melatonin and its benefits on cardiovascular disease

Br J Pharmacol. 2026 Sep 25. doi: 10.1111/bph.70673. Online ahead of print.ABSTRACTCardiovascular disease remains the leading cause of mortality globally, with a disproportionate burden in low- and middle-income countries. Melatonin, a hormone primarily produced by the pineal gland, exhibits notable

K Karabo Tisane

Cardiac Implantable Electronic Devices Management in Older Adults ≥75 Years Old: From Underrepresentation in Clinical Trials to Overrepresentation in Contemporary Clinical Practice

Curr Cardiol Rev. 2026 Sep 21. doi: 10.2174/011573403X485322260904063323. Online ahead of print.ABSTRACTCardiac Implantable Electronic Devices (CIEDs), ranging from Permanent Pacemakers (PPMs) for bradycardia, Implantable Cardioverter-Defibrillators (ICDs), to Cardiac Resynchronization Therapy (CRT)

M Matthew F Yuyun

Chronic Hypertension in Pregnancy: Risk Stratification, Management Strategies and Long-term Maternal-Fetal Outcomes

Curr Cardiol Rev. 2026 Sep 22. doi: 10.2174/011573403X512215260909111132. Online ahead of print.ABSTRACTINTRODUCTION/OBJECTIVES: Chronic hypertension in pregnancy is increasingly prevalent and is associated with substantial maternal and fetal morbidity, including superimposed preeclampsia, placental

S Sofia Lopes-Pereira

Architecture of the cardiac transverse-axial tubular system across different mammalian species

J Physiol. 2026 Sep 24. doi: 10.1113/JP291136. Online ahead of print.ABSTRACTCardiac excitation-contraction coupling relies on a pancellular network of regular cardiomyocyte surface membrane invaginations, termed the transverse-axial tubular system (TATS). The TATS is ubiquitously present in adult m

J Joachim Greiner

E3 Ubiquitin Ligase NEDD4-Mediated CTSB Ubiquitination Prevents Microglial Ferroptosis After Subarachnoid Hemorrhage

J Biochem Mol Toxicol. 2026 Oct;40(10):e71084. doi: 10.1002/jbt.71084.ABSTRACTTo investigate the role of cathepsin B (CTSB) in microglial ferroptosis after subarachnoid hemorrhage (SAH) and its upstream regulatory mechanisms. A SAH mouse model was established, and BV2 microglial cell line was utiliz

X Xiuyou Yan

Variations in Single-Point Insulin Sensitivity Estimator Index and the Risk of Cardiovascular Disease in Individuals With Cardiovascular-Kidney-Metabolic Syndrome Stages 0 to 3: A National Longitudinal Cohort Study

J Am Heart Assoc. 2026 Sep 24:e051048. doi: 10.1161/JAHA.126.051048. Online ahead of print.ABSTRACTBACKGROUND: Prior studies have focused exclusively on baseline single-point insulin sensitivity estimator (SPISE) index levels, and the prognostic impact of longitudinal SPISE index trajectories on inc

Y Yumeng Shi

Scope of Practice Laws Affecting Team-Based Heart Disease Care in Rural America: Policy Challenges and Opportunities

J Am Heart Assoc. 2026 Sep 24:e049493. doi: 10.1161/JAHA.126.049493. Online ahead of print.ABSTRACTBACKGROUND: Heart disease is the leading cause of death in the United States with a disproportionate impact in rural America, and health worker shortages contribute to these disparities. Team-based hea

J Jeff Lane

Septal Nonischemic Late Gadolinium Enhancement After Myocardial Infarction Is Associated With Adverse Remodeling and Improves Risk Stratification for Heart Failure Outcomes

J Am Heart Assoc. 2026 Sep 24:e049783. doi: 10.1161/JAHA.126.049783. Online ahead of print.ABSTRACTBACKGROUND: The prevalence, anatomic distribution, enhancement patterns, and prognostic value of nonischemic late gadolinium enhancement (NI-LGE) in patients with prior myocardial infarction were not s

P Pengyu Zhou

Door-to-Cardiac Rehabilitation Time and Clinical Outcomes in Patients Hospitalized for Acute Heart Failure: A Nationwide Japanese Registry

J Am Heart Assoc. 2026 Sep 24:e051493. doi: 10.1161/JAHA.126.051493. Online ahead of print.ABSTRACTBACKGROUND: Cardiac rehabilitation (CR) improves outcomes in heart failure, but optimal initiation timing during acute hospitalization remains undefined. We characterized the dose-response association

S Satoshi Katano

Ovariectomy and Chemical Ovarian Failure Exacerbate Atherosclerosis Without Impairing Recovery From Hindlimb Ischemia

J Am Heart Assoc. 2026 Sep 24:e053158. doi: 10.1161/JAHA.126.053158. Online ahead of print.ABSTRACTBACKGROUND: Peripheral artery disease is a major manifestation of atherosclerotic cardiovascular disease (ASCVD) that affects both men and women. In women, menopause increases the ASCVD risk. However,

M Mia Y Buck

Endocrine therapy adherence and 10-year cardiometabolic risk in hormone receptor-positive breast cancer

JNCI Cancer Spectr. 2026 Sep 24:pkag095. doi: 10.1093/jncics/pkag095. Online ahead of print.ABSTRACTBACKGROUND: Adjuvant endocrine therapy (AET) reduces breast cancer (BC) recurrence but may adversely affect cardiometabolic health. We evaluated the association between AET adherence duration and 10-y

J Jorge R Ledesma

JAK2V617F Mutation in Ischemic Stroke: Bridging Hematology and Stroke Neurology

J Am Heart Assoc. 2026 Sep 24:e050497. doi: 10.1161/JAHA.126.050497. Online ahead of print.ABSTRACTRecent evidence suggests the JAK2V617F mutation may confer an elevated risk of ischemic stroke, likely mediated by systemic inflammation, abnormal cell activation, and endothelial dysfunction. The JAK2

M Marie H Kristiansen

Insulin Resistance Indices and Genetic Predisposition in Relation to the Risk of Incident and Recurrent Coronary Artery Disease

J Am Heart Assoc. 2026 Sep 24:e049158. doi: 10.1161/JAHA.126.049158. Online ahead of print.ABSTRACTBACKGROUND: Insulin resistance contributes to the pathogenesis of coronary artery disease (CAD), yet its association with recurrent CAD and the potential role of genetic susceptibility remain unclear.M

Y Yihong Ding

Role of Inflammatory Markers in the Progression of Arterial Stiffness and Mortality: A Multicenter Longitudinal Cohort Study

J Am Heart Assoc. 2026 Sep 24:e049194. doi: 10.1161/JAHA.126.049194. Online ahead of print.ABSTRACTBACKGROUND: Inflammation is a well-known driver of cardiovascular disease, but its role in the progression of arterial stiffness remains incompletely defined.METHODS: Individuals undergoing brachial-an

K Kyung An Kim

Reproductive Characteristics, Postmenopausal Obesity, and Cardiovascular Disease Incidence in the Women's Health Initiative

J Am Heart Assoc. 2026 Sep 24:e049882. doi: 10.1161/JAHA.126.049882. Online ahead of print.ABSTRACTBACKGROUND: Early menarche, menopause, and short reproductive lifespan are risk factors for cardiovascular disease (CVD), but whether these reproductive characteristics are independently associated wit

J Jaclyn D Borrowman

Associations of Plasma Metal Exposure With the Risk and Severity of Acute Coronary Syndrome: Evidence From Epidemiological and Adverse Outcome Pathway Analyses

J Am Heart Assoc. 2026 Sep 24:e050201. doi: 10.1161/JAHA.126.050201. Online ahead of print.ABSTRACTBACKGROUND: Evidence links environmental metal exposure to cardiovascular disease, but its association with acute coronary syndrome (ACS) risk and severity remains insufficiently characterized.METHODS:

Z Zeyuan Fu

Achievement of the American Heart Association Life's Essential 8 Goals With Death Among American Indian People: The Strong Heart Family Study

J Am Heart Assoc. 2026 Sep 24:e048758. doi: 10.1161/JAHA.125.048758. Online ahead of print.ABSTRACTBACKGROUND: The American Heart Association's Life's Essential 8 is a metric used to assess cardiovascular health (CVH) that includes 4 health behaviors and 4 health factors. We examined the association

P Pyone Yadanar Paing

Stroke Burden Attributable to Risk Factors in the Americas, 1990 to 2021: A Temporal Trends Analysis From the GBD Study 2021

J Am Heart Assoc. 2026 Sep 24:e047114. doi: 10.1161/JAHA.125.047114. Online ahead of print.ABSTRACTBACKGROUND: Stroke burden varies across the Americas, yet data on modifiable risk factor contributions remain limited.METHODS: Using GBD (Global Burden of Disease) study 2021 data, we analyzed stroke m

F Felipe Fregni

Dexamethasone Nonsuppression in Primary Aldosteronism: Associations With Adrenal Imaging Findings

J Am Heart Assoc. 2026 Sep 24:e049591. doi: 10.1161/JAHA.126.049591. Online ahead of print.ABSTRACTBACKGROUND: The 1-mg dexamethasone suppression test (DST) nonsuppression is increasingly recognized beyond adrenal incidentaloma, but its prevalence and clinical significance in patients evaluated for

X Xiang-Tao Zhang