Redefining atherosclerotic cardiovascular disease patients with no standard modifiable risk factors "SMuRF-less": six rather than four risk factors. Analysis from the Jordan SMuRF-less Study

Front Cardiovasc Med. 2026 Aug 6;13:1785553. doi: 10.3389/fcvm.2026.1785553. eCollection 2026.ABSTRACTBACKGROUND: Atherosclerotic cardiovascular disease (ASCVD) is the leading cause of death in Middle East. Some patients sustain events in the absence of the four standard modifiable risk factors (SMu

A Ayman Hammoudeh

Transformer-based models for cardiovascular disease risk prediction: what is the potential?

No abstractEur Heart J. 2026 Aug 21:ehag641. doi: 10.1093/eurheartj/ehag641. Online ahead of print.NO ABSTRACTPMID:42625549 | DOI:10.1093/eurheartj/ehag641

L Lisa Pennells

Utility of serum HMGB1 in chronic obstructive pulmonary disease with pulmonary hypertension: A single-centre analysis

Pulmonology. 2026 Dec;32(1):2720837. doi: 10.1080/25310429.2026.2720837. Epub 2026 Aug 21.ABSTRACTBACKGROUND: Acute exacerbations of chronic obstructive pulmonary disease (AECOPD) with pulmonary hypertension (PH) worsen outcomes, yet reliable prognostic biomarkers remain lacking.RESEARCH QUESTION: W

Q Qian Lv

Arterial hypertension and bronchial asthma: phenotype, cardiovascular complications, and independent predictors - an analysis of 57,396 patients from a hypertension registry

Ter Arkh. 2026 Aug 18;98(8):472-477. doi: 10.26442/00403660.2026.08.203727.ABSTRACTBACKGROUND: The combination of arterial hypertension (AH) and bronchial asthma (BA) presents a complex clinical challenge that notably elevates cardiovascular risk. Real-world data are scarce regarding the phenotype a

A A V Aksenova

Evaluation of drug therapy in patients before major orthopaedic surgery from the perspective of a general practitioner: a real-world study

Ter Arkh. 2026 Aug 18;98(8):466-471. doi: 10.26442/00403660.2026.08.203726.ABSTRACTAIM: To evaluate the structure of cardiovascular pharmacotherapy prescribed during the preoperative period including antihypertensive, antiarrhythmic, antianginal, lipid-lowering, and antiplatelet drugs and to analyze

E E A Okisheva

Screening for Helicobacter pylori infection in patients with acute myocardial infarction and stable coronary artery disease: prevalence and risk factors (a single-center study)

Ter Arkh. 2026 Aug 18;98(8):458-465. doi: 10.26442/00403660.2026.08.203725.ABSTRACTAIM: To evaluate the prevalence and identify risk factors for Helicobacter pylori infection in patients with acute myocardial infarction (AMI) and stable coronary artery disease (CAD).MATERIALS AND METHODS: A total of

E E S Deeva

Predictors of surgical intervention in patients with ulcerative, pseudomembranous, and ischemic colitis

Ter Arkh. 2026 Aug 18;98(8):439-445. doi: 10.26442/00403660.2026.08.203723.ABSTRACTAIM: To compare surgical and conservative treatment outcomes in patients with severe and fulminant ulcerative colitis (UC), pseudomembranous colitis (PMC), and ischemic colitis (IC) and to identify predictors of surgi

G G A Krotov

Renin-Angiotensin System Inhibitor Use and Mortality in Older Hypertensive Patients With and Without Dementia: A Nationwide Registry-Based Cohort Study

J Clin Hypertens (Greenwich). 2026 Aug;28(8):e70350. doi: 10.1111/jch.70350.ABSTRACTCardiovascular risk factors are often undertreated in patients with dementia. Renin-angiotensin system inhibitors (RASI) are first-line treatments for hypertension. We examined the association between RASI and all-ca

M Marta Villa Lopez

Twenty-Four-Hour Blood Pressure Variability Combined With Circadian Rhythm Patterns in Predicting Cardiovascular Events in Hypertensive Patients

J Clin Hypertens (Greenwich). 2026 Aug;28(8):e70342. doi: 10.1111/jch.70342.ABSTRACTShort-term blood pressure variability (BPV) and circadian BP abnormalities are important cardiovascular risk predictors of mean BP levels, but their combined prognostic significance in essential hypertension remains

Q Qin Ma

MIND diet, cerebrovascular health, and cognition among community-dwelling older adults

Alzheimers Dement. 2026 Aug;22(8):e71772. doi: 10.1002/alz.71772.ABSTRACTINTRODUCTION: Understanding of the Mediterranean-Dietary Approaches to Stop Hypertension Intervention for Neurodegenerative Disease (MIND) diet's association with cerebral arteriosclerosis, and whether cerebrovascular outcomes

P Puja Agarwal

Sudden cardiac death in chronic kidney disease and dialysis: From descriptive epidemiology to mechanism-driven prevention

J Intern Med. 2026 Aug 21. doi: 10.1111/joim.70127. Online ahead of print.ABSTRACTSudden cardiac death (SCD) is a leading cause of mortality across the chronic kidney disease (CKD) continuum and becomes particularly prominent in dialysis-dependent kidney failure. In hemodialysis, SCD accounts for ro

C Carmine Zoccali

Empagliflozin inhibits cardiac hypertrophy via a mechanism involving integrin signalling

Br J Pharmacol. 2026 Aug 21. doi: 10.1111/bph.70637. Online ahead of print.ABSTRACTBACKGROUND AND PURPOSE: Pathological cardiac hypertrophy precipitates heart failure. Empagliflozin (EMPA), a sodium-glucose cotransporter 2 (SGLT2) inhibitor, confers cardiovascular protection beyond glycaemic control

G Gan Qiao

A Tiered Genetic Diagnostic Approach in Newborns With Major Congenital Anomalies: Experience From a Tertiary NICU

Birth Defects Res. 2026 Aug;118(8):e70108. doi: 10.1002/bdr2.70108.ABSTRACTBACKGROUND: Major congenital anomalies (MCAs) are a leading cause of neonatal morbidity and mortality and frequently reflect underlying chromosomal, copy number, or single-gene defects. In neonates with multiple MCAs, early m

H Hatice Mutlu

Drug Resistance in Multiple Myeloma: Tumor-Intrinsic Mechanisms and the Bone Marrow Microenvironment

Cell Biochem Funct. 2026 Aug;44(8):e70286. doi: 10.1002/cbf.70286.ABSTRACTMultiple myeloma (MM) is a malignant plasma cell disorder, and despite substantial improvements in prognosis achieved through chemotherapy, immunotherapy, and autologous stem cell transplantation, most patients ultimately deve

Y Yixuan Chen

Downregulation of Lgals3 Alleviates Inflammatory Response and Apoptosis in a Mouse Model of Cerebral Ischemia/Reperfusion Injury

Brain Behav. 2026 Aug;16(8):e71700. doi: 10.1002/brb3.71700.ABSTRACTPURPOSE: The present work investigated the expression and function of Lgals3 in cerebral ischemia/reperfusion (cerebral IR) injury.METHODS: Differentially expressed genes in cerebral IR were analyzed by the Gene Expression Omnibus (

Z Zhaodan Gan

MicroRNA and Inflammatory Biomarker Signatures Associated With Neurological Outcome After Out-Of-Hospital Cardiac Arrest: The MiRacle Study

Eur J Clin Invest. 2026 Aug;56(8):e70251. doi: 10.1111/eci.70251.ABSTRACTBACKGROUND: Early neuroprognostication in Out-of-Hospital Cardiac Arrest (OHCA) remains challenging due to the lack of reliable biomarkers. Circulating microRNAs have emerged as potential indicators of inflammation and brain in

F Francisco Rafael Jiménez-Trinidad

DUSP1 Inhibits Mechanotransduction and MAPK Signalling to Alleviate Myocardial Cell Hypertrophy

Clin Exp Pharmacol Physiol. 2026 Sep;53(9):e70152. doi: 10.1111/1440-1681.70152.ABSTRACTHypertrophic Cardiomyopathy (HCM) is one of the significant causes of heart failure. This study aimed to identify and validate potential therapeutic targets for HCM through bioinformatics analysis and in vitro an

X Xiao Zhong

Left Ventricular Summit Ventricular Tachycardia Identified by Electrocardiographic Pattern Recognition and Managed With Radiofrequency Ablation

Am J Case Rep. 2026 Aug 21;27:e953321. doi: 10.12659/AJCR.953321.ABSTRACTBACKGROUND Left ventricular summit ventricular tachycardia (LVSVT) originates in the epicardium of the superior left ventricular wall, between the origins of the main coronary arteries, with characteristic findings on 12-lead e

M Mariana Goes Moreira

Estimated pulse wave velocity as an integrated hemodynamic risk indicator in obese women with gestational hypertension: A cross-sectional study

Physiol Rep. 2026 Aug;14(16):e71078. doi: 10.14814/phy2.71078.ABSTRACTHypertensive disorders of pregnancy are associated with increased cardiovascular risk and arterial remodeling, further complicated by obesity. While carotid-femoral pulse wave velocity remains the gold standard for arterial stiffn

L Longa Kaluba

Multitarget Regulatory Mechanisms and Research Advances of Plant-Derived Bioactive Ingredients in Hypertension Prevention and Management

Phytother Res. 2026 Aug 20. doi: 10.1002/ptr.70428. Online ahead of print.ABSTRACTHypertension remains a major global risk factor for cardiovascular diseases, yet current treatments face challenges such as suboptimal blood pressure control and inadequate organ protection. Plant-derived bioactive ing

Q Qiqi Deng

Corylin Confers Vasoprotection via JDP2-Nrf2 Antioxidant Axis against Chronic Kidney Disease-Induced Smooth Muscle Cell Remodelling

J Cell Mol Med. 2026 Aug;30(16):e71331. doi: 10.1111/jcmm.71331.ABSTRACTVascular calcification is a pathological process involving vascular smooth muscle cells (VSMCs) phenotypic switching into osteoblast-like cells within a calcium phosphate-deposited environment. This transformation is a critical

S Shang-En Huang

Pediatric Hyperlipidemia Guidelines: A Comprehensive Review of Screening, Diagnosis, and Management

Cardiol Rev. 2026 Aug 21. doi: 10.1097/CRD.0000000000001433. Online ahead of print.ABSTRACTAtherosclerotic cardiovascular disease originates in childhood, and cumulative exposure to low-density lipoprotein cholesterol (LDL-C) is a major determinant of lifetime cardiovascular risk. Multiple professio

N Nhi D Nguyen

Utility of artificial intelligence in predicting clinical outcomes of angiographic procedures: a comprehensive scoping review

J Cardiovasc Imaging. 2026 Aug 20;34(1):24. doi: 10.1186/s44348-026-00064-x.ABSTRACTArtificial intelligence (AI) is emerging as a transformative tool in cardiovascular imaging, particularly in coronary angiography. With the growing interest in precision medicine, AI offers the potential to enhance c

S Shreeyash Shashank Tulpule

A cardiometabolic perspective on post-exertional malaise in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and Long COVID

Cardiovasc Diabetol. 2026 Aug 20;25(1):250. doi: 10.1186/s12933-026-03316-8.ABSTRACTPost-exertional malaise (PEM), the defining feature of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), is increasingly recognized in individuals with Long COVID. Although traditionally viewed as symptom

F Francisco Westermeier