Cologne (Germany): Institute for Quality and Efficiency in Health Care (IQWiG); 2026 Feb 22.ABSTRACTRESEARCH QUESTION: The aim of this report is toassess the benefit of diagnostics using cardiac magnetic resonance imaging as part of a diagnostic strategy, compared with a diagnostic strategy without
Am J Trop Med Hyg. 2025 Dec 23:tpmd250017. doi: 10.4269/ajtmh.25-0017. Online ahead of print.ABSTRACTCardiovascular diseases (CVD) is a public health issue in low- and middle-income countries. Identification of subclinical carotid atherosclerosis (SCA) might contribute to the prevention of life-thre
JMIR Res Protoc. 2026 Feb 10;15:e87035. doi: 10.2196/87035.ABSTRACTBACKGROUND: Intensive therapies based on motor skill learning have been widely used in stroke rehabilitation for improving upper extremity abilities, demonstrating significant improvements in arm function and daily life activities. B
Eur J Cardiothorac Surg. 2026 Feb 5;68(2):ezag063. doi: 10.1093/ejcts/ezag063.ABSTRACTOBJECTIVES: Congenital aortic valve (AoV) disease has limited treatment options in growing children. Different initial strategies, AoV repair/surgical valvuloplasty (SAV), AoV replacement (AVR), and Ross procedure
PLoS One. 2026 Feb 10;21(2):e0341594. doi: 10.1371/journal.pone.0341594. eCollection 2026.ABSTRACTBACKGROUND: Footwear and insoles are frequently used to offload the neuropathic diabetic foot at risk of ulceration and re-ulceration. This study aims to explore the prescription habits of Australian pe
PLoS One. 2026 Feb 10;21(2):e0342473. doi: 10.1371/journal.pone.0342473. eCollection 2026.ABSTRACTOBJECTIVES: Targeted temperature management (TTM) has been a fundamental component of post-resuscitation care for patients experiencing cardiac arrest for many years. This study aims to investigate the
PLoS Genet. 2026 Feb 10;22(2):e1011489. doi: 10.1371/journal.pgen.1011489. Online ahead of print.ABSTRACTCongenital heart disease (CHD) is a major cause of infant mortality and presents life-long challenges to individuals living with these conditions. Genetic causes are known for only a minority of
PLoS One. 2026 Feb 10;21(2):e0339837. doi: 10.1371/journal.pone.0339837. eCollection 2026.ABSTRACTBACKGROUND: Mitral regurgitation (MR) and tricuspid regurgitation (TR) commonly coexist in patients with heart failure (HF). Their concomitant occurrence carries a much poorer prognosis than isolated va
PLoS One. 2026 Feb 10;21(2):e0339491. doi: 10.1371/journal.pone.0339491. eCollection 2026.ABSTRACTBACKGROUND: Clonal hematopoiesis of indeterminate potential (CHIP) is the age-related presence of expanded somatic clones secondary to leukemogenic driver mutations and is associated with cardiovascular
Health Policy Plan. 2026 Feb 10:czag016. doi: 10.1093/heapol/czag016. Online ahead of print.ABSTRACTSub-Saharan Africa (SSA) is experiencing an epidemiological transition where non-communicable diseases are becoming the leading cause of disability and mortality alongside infectious diseases such as
PLoS One. 2026 Feb 10;21(2):e0341438. doi: 10.1371/journal.pone.0341438. eCollection 2026.ABSTRACTINTRODUCTION: Evaluating pulmonary circulation parameters (PCP) with cardiovascular magnetic resonance (CMR) is a relatively new approach with the potential for complex evaluation of the cardio-pulmonar
Clin Transl Med. 2026 Feb;16(2):e70618. doi: 10.1002/ctm2.70618.ABSTRACTBACKGROUND: Immunotherapy has revolutionized the treatment of malignant tumors; however, it may lead to fatal cardiotoxicity. Herein, we explored the mechanisms underlying cardiac side-effects induced by immune checkpoint inhibi
J Clin Invest. 2026 Feb 3:e198545. doi: 10.1172/JCI198545. Online ahead of print.ABSTRACTBackground Youth with type 2 diabetes (T2D) and severe obesity face high risk of diabetic kidney disease, which metabolic bariatric surgery (MBS) can mitigate. This study explores structural and molecular change
J Am Soc Nephrol. 2026 Feb 10. doi: 10.1681/ASN.0000001008. Online ahead of print.ABSTRACTBACKGROUND: Autosomal dominant polycystic kidney disease (ADPKD) is the leading monogenic cause of kidney failure and affects millions of people worldwide. Despite the prevalence of ADPKD, limited mechanistic u
J Clin Invest. 2026 Feb 10:e201762. doi: 10.1172/JCI201762. Online ahead of print.ABSTRACTBACKGROUND: MASLD has a substantial inherited component. Rare variants in Apolipoprotein B gene (APOB) have been implicated in susceptibility to liver steatosis, but their role in disease progression and outcom
Hepatol Commun. 2025 Nov 24;9(12):e0853. doi: 10.1097/HC9.0000000000000853. eCollection 2025 Dec 1.ABSTRACTBACKGROUND: Kupffer cells (KCs) are the tissue-resident macrophages of the liver, where they serve a critical role in maintaining liver tissue homeostasis and act as a filter for circulation. T
No abstractNephrol Dial Transplant. 2026 Feb 10:gfag026. doi: 10.1093/ndt/gfag026. Online ahead of print.NO ABSTRACTPMID:41665876 | DOI:10.1093/ndt/gfag026
J Physiol Biochem. 2026 Feb 10;82(1):9. doi: 10.1007/s13105-026-01145-7.ABSTRACTAging heightens susceptibility to ischemia-reperfusion (IR) injury, complicating liver transplantation, while the nucleotide-binding oligomerization domain (NOD)-like receptor pyrin domain containing 3 (NLRP3) inflammaso
Neurotox Res. 2026 Feb 10;44(1):8. doi: 10.1007/s12640-026-00783-5.ABSTRACTArsenic is a prevalent and significant cause of poisoning worldwide, leading to both acute and chronic toxicity. The life-threatening nature of arsenic toxicity is evident in its link to fatal health conditions in different p
Clin Auton Res. 2026 Feb 10. doi: 10.1007/s10286-026-01187-3. Online ahead of print.ABSTRACTPURPOSE: The growing recognition of autonomic nervous system (ANS) dysfunction across a broad spectrum of neurological and systemic diseases calls for structured, multidisciplinary care. This position stateme
Eur J Clin Pharmacol. 2026 Feb 10;82(3):78. doi: 10.1007/s00228-026-04010-0.ABSTRACTBACKGROUND: Sepsis-induced cardiac dysfunction significantly impacts patient outcomes, with inotropic support playing a crucial role in management. Levosimendan and dobutamine are commonly used, but their comparative
No abstractCurr Atheroscler Rep. 2026 Feb 10;28(1):20. doi: 10.1007/s11883-026-01396-1.NO ABSTRACTPMID:41665731 | DOI:10.1007/s11883-026-01396-1
J Neurol. 2026 Feb 10;273(2):131. doi: 10.1007/s00415-026-13641-3.ABSTRACTPURPOSE: Head-Impulse, Nystagmus, Test-of-Skew (HINTS) testing is recommended to identify stroke in the acute vestibular syndrome (AVS). Diagnostic accuracy depends on the vascular territory involved, with lower sensitivity fo
Curr Cardiol Rep. 2026 Feb 10;28(1):23. doi: 10.1007/s11886-025-02341-5.ABSTRACTPURPOSE OF REVIEW: As the obesity epidemic expands, the alarming acceleration of youth obesity represents a critical global health concern. This timely analysis explores the underlying biological and socio-environmental
