Biofactors. 2026 Sep-Oct;52(5):e70162. doi: 10.1002/biof.70162.ABSTRACTHigh-density lipoprotein (HDL) is a cholesterol transporter that plays a well-defined role in reverse cholesterol transport. In addition, HDL shows anti-inflammatory and immunomodulatory functions mainly due to its ability to dec
Stat Med. 2026 Oct;45(23-24):e70783. doi: 10.1002/sim.70783.ABSTRACTIn the absence of censoring, locally estimated scatterplot smoothing (LOESS) is a powerful tool to estimate the relationship between a continuous covariate and the probability of an event and is often used to visually assess calibra
Pediatr Transplant. 2026 Oct;30(10):e70503. doi: 10.1111/petr.70503.ABSTRACTBACKGROUND: Acute kidney injury (AKI) has been associated with diastolic dysfunction in pre-clinical studies, but with limited evaluation in clinical settings. We sought to examine the association between post-operative AKI
BJOG. 2026 Oct 16. doi: 10.1111/1471-0528.70341. Online ahead of print.ABSTRACTOBJECTIVE: To assess the association between blood pressure values at 6 weeks postpartum and subsequent cardiovascular disease (CVD) over a 20-year period among women with hypertensive disorders of pregnancy (HDP).DESIGN:
Clin Exp Pharmacol Physiol. 2026 Oct;53(10):e70161. doi: 10.1111/1440-1681.70161.ABSTRACTPulmonary arterial hypertension (PAH) is characterized by pulmonary endothelial cell (EC) dysfunction and pulmonary vascular remodelling. Endothelial-to-mesenchymal transition (EndMT) is a key mechanism underlyi
Med Sci Monit. 2026 Oct 17;32:e954116. doi: 10.12659/MSM.954116.ABSTRACTBACKGROUND Cardiovascular-kidney-metabolic (CKM) syndrome reframes cardio-renal-metabolic risk but omits hepatic dysfunction, particularly metabolic dysfunction-associated fatty liver disease (MAFLD). This study assesses whether
J Cell Mol Med. 2026 Oct;30(20):e71383. doi: 10.1111/jcmm.71383.ABSTRACTPeripheral arterial disease (PAD) impairs limb perfusion, leading to myopathy characterised by altered mitochondrial content and respiration. Because ischemic muscle appears to adapt differently across PAD stages, we examined st
Medicine (Baltimore). 2026 Oct 16;105(42):e51073. doi: 10.1097/MD.0000000000051073.ABSTRACTCirculating tumor plasma cells (CTPCs) detected by multiparameter flow cytometry may serve as a minimally invasive marker of disease burden in multiple myeloma (MM). However, the relationship between CTPC burd
Medicine (Baltimore). 2026 Oct 16;105(42):e51242. doi: 10.1097/MD.0000000000051242.ABSTRACTDiabetic foot ulcers (DFUs) are a major cause of lower-extremity amputation, hospitalization, and mortality. Although management focuses on wound care, infection control, and limb preservation, malignancies ma
Medicine (Baltimore). 2026 Oct 16;105(42):e51189. doi: 10.1097/MD.0000000000051189.ABSTRACTAcute ischemic stroke (AIS) can occur in patients with non-valvular atrial fibrillation (AF) despite treatment with non-vitamin K antagonist oral anticoagulants (NOACs). This study evaluated clinical, treatmen
Medicine (Baltimore). 2026 Oct 16;105(42):e49302. doi: 10.1097/MD.0000000000049302.ABSTRACTInadequate and poor-quality sleep is increasingly recognized as a risk factor for coronary artery disease (CAD). Gut microbiota may play a role in sleep regulation. However, the associations between gut microb
Medicine (Baltimore). 2026 Oct 16;105(42):e51200. doi: 10.1097/MD.0000000000051200.ABSTRACTCirrhotic cardiomyopathy (CCM) is a prevalent yet frequently underrecognized cardiac complication of liver cirrhosis, characterized by impaired myocardial contractile reserve, diastolic dysfunction, and electr
Medicine (Baltimore). 2026 Oct 16;105(42):e51143. doi: 10.1097/MD.0000000000051143.ABSTRACTCardiovascular disease (CVD) is a major cause of excess mortality among patients with rheumatoid arthritis (RA). Conventional risk assessment may not fully capture the metabolic abnormalities and physiological
Medicine (Baltimore). 2026 Oct 16;105(42):e51160. doi: 10.1097/MD.0000000000051160.ABSTRACTNational long-term trends and disparities in deaths in which both chronic obstructive pulmonary disease (COPD) and cardiac arrest are recorded on death certificates are not well characterized. We used CDC WOND
Medicine (Baltimore). 2026 Oct 16;105(42):e51178. doi: 10.1097/MD.0000000000051178.ABSTRACTThe causal relationship between Helicobacter pylori antibodies and the risk of cerebral aneurysms remains unclear. We used Mendelian randomization analysis to assess the causal relationship between Helicobacte
Medicine (Baltimore). 2026 Oct 16;105(42):e51166. doi: 10.1097/MD.0000000000051166.ABSTRACTEndothelial dysfunction is prevalent in type 2 diabetes mellitus (T2DM) with coronary heart disease (CHD), increasing cardiovascular risk. The Endothelial Activation and Stress Index (EASIX) is a novel composi
Medicine (Baltimore). 2026 Oct 16;105(42):e50862. doi: 10.1097/MD.0000000000050862.ABSTRACTEvidence on the association between cardiovascular health (CVH) and frailty remains limited, and the role of serum 25-hydroxyvitamin D (25(OH)D) in this relationship is not fully understood. This study aimed t
Medicine (Baltimore). 2026 Oct 16;105(42):e51137. doi: 10.1097/MD.0000000000051137.ABSTRACTPulmonary thromboembolism (PTE) is a severe and potentially fatal complication in patients with malignancy. Systemic inflammation plays an important role in both cancer progression and thrombogenesis. This stu
Medicine (Baltimore). 2026 Oct 16;105(42):e51090. doi: 10.1097/MD.0000000000051090.ABSTRACTThyroid disorders frequently coexist with cardiovascular disease, including hypertension, but whether long-term modulation of antihypertensive drug targets influences thyroid disease risk remains uncertain. We
Medicine (Baltimore). 2026 Oct 16;105(42):e51089. doi: 10.1097/MD.0000000000051089.ABSTRACTInsulin resistance, adiposity, kidney dysfunction, and cardiovascular disease are closely interconnected in middle-aged and older adults and are central to the cardiovascular-kidney-metabolic (CKM) framework.
Pharmacol Res Perspect. 2026 Dec;14(6):e70334. doi: 10.1002/prp2.70334.ABSTRACTPathological cardiac hypertrophy is initially an adaptive response to sustained mechanical, neurohormonal, or metabolic stress; however, it can progress to fibrosis, contractile dysfunction, arrhythmia, and heart failure.
Nurs Open. 2026 Oct;13(10):e70886. doi: 10.1002/nop2.70886.ABSTRACTAIM: To explore, including from a gender perspective, how people who have suffered a myocardial infarction describe the changes they need to adopt during the recovery phase following hospital discharge.DESIGN: Qualitative interpretiv
Gen Thorac Cardiovasc Surg Cases. 2026 Oct 16;5(1):46. doi: 10.1186/s44215-026-00273-2.ABSTRACTBACKGROUND: Saphenous vein graft pseudoaneurysm is a rare late complication of coronary artery bypass grafting. Management is particularly challenging when the pseudoaneurysm-bearing graft remains an activ
Syst Rev. 2026 Oct 17;15(1):272. doi: 10.1186/s13643-026-03359-8.ABSTRACTBACKGROUND AND AIM: Although studies have confirmed that disruptions in the gut microbiota (dysbiosis) contribute to the development of autoimmune disorders, the precise pathways through which the gut microbiota influences the
