Triglyceride glucose index-a body shape index (TyG-ABSI) outperforms traditional obesity indices in predicting all-cause and cardiovascular mortality in metabolic-dysfunction associated steatotic liver disease: the mediating role of biological aging

Cardiovasc Diabetol. 2026 Feb 22. doi: 10.1186/s12933-026-03112-4. Online ahead of print.ABSTRACTBACKGROUND: Metabolic dysfunction-associated steatotic liver disease (MASLD) is burdened by significant all-cause and cardiovascular mortality, yet simple and effective predictive indices for long-term o

G Guodong Yang

Spatially resolved transcriptomic profiling identifies distinct signatures in parenchymal and vascular microenvironments in Alzheimer's Disease with Cerebral Amyloid Angiopathy

Alzheimers Dement. 2026 Feb;22(2):e71208. doi: 10.1002/alz.71208.ABSTRACTINTRODUCTION: Alzheimer's disease (AD) pathology frequently coexists with cerebral amyloid angiopathy (CAA), in which amyloid beta (Aβ) deposits in cerebral blood vessels. Although anti-Aβ immunotherapies can reduce parenchymal

E Enrique Chimal-Juárez

Effect of preoperative liposomal bupivacaine single-injection pericapsular nerve group (PENG) block on lower extremity deep vein thrombosis in elderly patients with hip fractures: a randomised controlled, double-blind, prospective clinical study protocol

BMJ Open. 2026 Feb 22;16(2):e111579. doi: 10.1136/bmjopen-2025-111579.ABSTRACTINTRODUCTION: Deep vein thrombosis (DVT) of the lower limbs has a significantly higher incidence among elderly populations than that observed in other types of fractures, prolonged immobilisation and the systemic inflammat

H Haobin Peng

Comparative risk of the neurodegenerative outcomes between sodium-glucose co-transporter 2 (SGLT2) inhibitors and thiazolidinediones in type 2 diabetes: a multicentre cohort study using the Korean healthcare database (2014-2025)

BMJ Open. 2026 Feb 22;16(2):e105271. doi: 10.1136/bmjopen-2025-105271.ABSTRACTOBJECTIVE: Type 2 diabetes mellitus has been associated with an increased risk of cognitive decline and dementia, with patients being 1.5-2 times more likely to develop these conditions. While both sodium-glucose co-transp

S Sang Joon Park