Glia. 2026 Dec;74(12):e70228. doi: 10.1002/glia.70228.ABSTRACTNeuroimmune responses critically shape the progression and outcome of ischemic stroke, yet the cell type-specific roles of myeloid populations remain incompletely defined. Cathepsin B (CatB), a lysosomal cysteine protease, has been implic
Eur J Heart Fail. 2026 Oct 1:xuag301. doi: 10.1093/ejhf/xuag301. Online ahead of print.ABSTRACTHeart failure (HF) remains a major cause of morbidity, mortality, and increased healthcare costs worldwide, and is recognized as the result of progressive cardiovascular-kidney-metabolic (CKM) syndrome. Ob
IUBMB Life. 2026 Oct;78(10):e70124. doi: 10.1002/iub.70124.ABSTRACTStroke is a leading cause of global mortality and morbidity, yet its underlying metabolic mechanisms remain largely undefined. Elucidating the causal role of blood metabolites in stroke pathogenesis is crucial for developing effectiv
J Pak Med Assoc. 2026 Sep;76(Suppl 1)(9):S14. doi: 10.47391/JPMA-7ANOS-ABS-13.ABSTRACTOBJECTIVES: Malignant brain neoplasms and cardiac arrest represent significant causes of mortality with potentially shared pathophysiological mechanisms and disparate population impacts. This study examines trends
Cardiovasc Ther. 2026;2026(1):e1295386. doi: 10.1155/cdr/1295386.ABSTRACTBACKGROUND: Managing STEMI and high-risk NSTEMI-equivalent patients on chronic oral anticoagulation (OAC) undergoing primary PCI poses competing ischaemic and bleeding risks.METHODS: This single-centre retrospective study enrol
Sensors (Basel). 2026 Sep 19;26(18):5936. doi: 10.3390/s26185936.ABSTRACTBackground and Objective: Obstructive sleep apnea (OSA) is a fatal widespread sleep-related breathing disorder and a major risk factor for cardiovascular and cerebrovascular diseases, significantly impacting older adults' healt
Rev Med Suisse. 2026 Sep 30;22(977):1596-1598. doi: 10.53738/REVMED.2026.22.977.49057.ABSTRACTA 44-year old patient presents at the emergencies for a cut above his right eyebrow. Inspection reveals a bilateral bilateral xanthelasma palpebrum (XP). The blood analysis shows a normal cholesterol level:
Sensors (Basel). 2026 Sep 19;26(18):5933. doi: 10.3390/s26185933.ABSTRACTWearable ECG increasingly records fewer than the standard 12 leads, so a model must be accurate, interpretable, and explicit about the information lost under lead reduction. I-GraphECG is a gray-box graph electrophysiology surr
Artif Organs. 2026 Sep 30. doi: 10.1111/aor.70244. Online ahead of print.ABSTRACTBACKGROUND: Univentricular circulations are initially established with the placement of a fixed-diameter blood shunt to facilitate physiologic stability during growth. This fixed-diameter shunt (FDS) is geometrically st
Aging Cell. 2026 Oct;25(10):e70748. doi: 10.1111/acel.70748.ABSTRACTCardiovascular diseases are the leading cause of mortality worldwide, with myocardial infarction (MI) contributing significantly to this burden. While age-related differences in cardiac remodeling and healing post MI are well-docume
Curr Opin HIV AIDS. 2026 Nov 1;21(6):480-487. doi: 10.1097/COH.0000000000001069. Epub 2026 Oct 1.ABSTRACTPURPOSE OF REVIEW: Weight gain and associated adipose tissue remodeling have been partly linked to HIV infection and to some current antiretroviral therapy (ART) regimens in ART-naive and ART-con
Curr Opin Pulm Med. 2026 Nov 1;32(6):543-550. doi: 10.1097/MCP.0000000000001303. Epub 2026 Oct 1.ABSTRACTPURPOSE OF REVIEW: The improved survival of people with HIV (PWH) comes with increasing exposure to age-related, metabolic, neuropsychiatric, and cardiovascular risk factors that predispose them
Eur J Prev Cardiol. 2026 Oct 1:zwag507. doi: 10.1093/eurjpc/zwag507. Online ahead of print.ABSTRACTAIMS: Preeclampsia is associated with future cardiovascular disease (CVD), yet systematic approaches to identify those requiring intensified prevention are lacking. We aimed to characterise these women
Am J Case Rep. 2026 Oct 1;27:e954070. doi: 10.12659/AJCR.954070.ABSTRACTBACKGROUND Central retinal artery occlusion (CRAO) is an ophthalmic emergency and a retinal ischemic stroke. Cilioretinal arteries may remain perfused during CRAO because they arise from the posterior ciliary circulation. Most r
Curr Vasc Pharmacol. 2026 Sep 29. doi: 10.2174/0115701611491082260918125921. Online ahead of print.ABSTRACTINTRODUCTION: Chronic coronary disease (CCD) commonly coexists with long-term oral anticoagulation (OAC), particularly for atrial fibrillation (AF). Combination antiplatelet therapy increases b
Curr Stem Cell Res Ther. 2026 Sep 29. doi: 10.2174/011574888X500658260921112146. Online ahead of print.ABSTRACTINTRODUCTION: Cell-based myocardial repair has progressed from direct cell replacement toward paracrine, engineered tissue, and cell-free strategies, but the relationship between preclinica
Endocrinol Diabetes Metab. 2026 Nov;9(6):e70318. doi: 10.1002/edm2.70318.ABSTRACTBACKGROUND: Sodium-glucose cotransporter-2 (SGLT-2) inhibitors have become a key drug class in the treatment of Type 2 diabetes (T2D) due to their effectiveness in blood sugar control, but also for many other clinical i
CNS Neurosci Ther. 2026 Oct;32(10):e71188. doi: 10.1002/cns.71188.ABSTRACTBACKGROUND: Cerebral small vessel disease (CSVD) is the key pathological basis of vascular depression. The precise identification of its neuroimaging markers is of core value for early diagnosis, elucidation of its pathologica
Nurs Open. 2026 Oct;13(10):e70884. doi: 10.1002/nop2.70884.ABSTRACTAIM: To evaluate differences in eating behaviours between nurses working exclusively daytime shifts and those engaged in night shift work.BACKGROUND: A growing body of evidence suggests that night shift work exposed nurses to an incr
Physiol Rep. 2026 Sep;14(19):e71119. doi: 10.14814/phy2.71119.ABSTRACTMacrophages are major contributors to inflammatory responses in acute kidney injury (AKI) and rapidly alter their gene expression through epigenetic regulation. This study focused on ASXL1, a chromatin modifier regulating histone
J Clin Apher. 2026 Oct;41(5):e70185. doi: 10.1002/jca.70185.ABSTRACTCitrate anticoagulation during therapeutic plasma exchange (TPE) chelates divalent cations and can precipitate torsades de pointes (TdP) in patients with pre-existing repolarization vulnerability. We report a 44-year-old woman with
Endocrinol Diabetes Metab. 2026 Nov;9(6):e70353. doi: 10.1002/edm2.70353.ABSTRACTINTRODUCTION: Dyslipidaemia remains a major contributor to atherosclerotic cardiovascular disease (ASCVD), and many patients fail to achieve recommended low-density lipoprotein cholesterol (LDL-C) targets despite statin
Colorectal Dis. 2026 Oct;28(10):e70641. doi: 10.1111/codi.70641.ABSTRACTBACKGROUND: Conventional excisional haemorrhoidectomy remains the gold standard treatment for grade IV haemorrhoids, although energy-based devices may reduce postoperative pain. We performed a systematic review and meta-analysis
J Med Case Rep. 2026 Sep 30;20(1):579. doi: 10.1186/s13256-026-06651-2.ABSTRACTBACKGROUND: Phlegmon is a severe skin and soft tissue infection (SSTI) that can escalate rapidly if not promptly recognized and treated. Its early presentation may appear deceptively mild, potentially delaying recognition
