Scand J Immunol. 2026 Jan;103(1):e70086. doi: 10.1111/sji.70086.ABSTRACTPeripheral immune tolerance is a cardinal feature of the adaptive immune system, which makes self-nonself discrimination and unresponsiveness toward self-antigens. Disruption in the regulation of these processes leads to damage
Mol Biomed. 2026 Jan 5;7(1):1. doi: 10.1186/s43556-025-00400-5.ABSTRACTInflammation resolution is now understood as an active and highly coordinated biological process rather than a passive decline in inflammatory signals. When this program fails, inflammation may become persistent and gradually shi
Hypertens Res. 2026 Jan 5. doi: 10.1038/s41440-025-02449-9. Online ahead of print.ABSTRACTBACKGROUNDS: The AFIRE (Atrial Fibrillation and Ischemic Events with Rivaroxaban in Patients with Stable Coronary Artery Disease) trial demonstrated that rivaroxaban monotherapy was non-inferior in efficacy and
Nanomicro Lett. 2026 Jan 5;18(1):164. doi: 10.1007/s40820-025-02003-9.ABSTRACTAccurate blood pressure (BP) monitoring is essential for preventing and managing cardiovascular disease. Advancements in materials science, medicine, flexible electronic, and artificial intelligence (AI) have enabled cuffl
Cell Res. 2026 Jan;36(1):11-37. doi: 10.1038/s41422-025-01203-7. Epub 2026 Jan 5.ABSTRACTMitophagy, an evolutionarily conserved quality-control process, selectively removes damaged mitochondria to maintain cellular homeostasis. Recent advances in our understanding of the molecular machinery underlyi
No abstractSci Rep. 2026 Jan 5. doi: 10.1038/s41598-025-34876-6. Online ahead of print.NO ABSTRACTPMID:41486197 | DOI:10.1038/s41598-025-34876-6
Clin Chem Lab Med. 2026 Jan 6. doi: 10.1515/cclm-2025-1605. Online ahead of print.ABSTRACTOBJECTIVES: Lipoprotein(a) is an atherogenic particle causative of atherosclerotic cardiovascular disease. Novel treatments have been developed that lower lipoprotein(a) to unprecedented levels with cardiovascu
J Clin Lipidol. 2025 Dec 1:S1933-2874(25)00524-0. doi: 10.1016/j.jacl.2025.11.017. Online ahead of print.ABSTRACTBACKGROUND: Rare variants in SCARB1, which encodes the high-density lipoprotein (HDL) receptor scavenger receptor class B type 1 (SR-B1), are hypothesized to drive unexplained extreme lev
Nutr Metab Cardiovasc Dis. 2025 Dec 1:104484. doi: 10.1016/j.numecd.2025.104484. Online ahead of print.ABSTRACTThe integrity of the vascular endothelium is fundamental to regulating cardio-metabolic and neurological functions. Endothelial dysfunction (ED) is a key driver of atherosclerosis and is st
J Cardiothorac Vasc Anesth. 2025 Dec 7:S1053-0770(25)01208-X. doi: 10.1053/j.jvca.2025.12.005. Online ahead of print.ABSTRACTOBJECTIVES: The primary aim of this work was to determine the rate of successful first-attempt tracheal intubation and the incidence of difficult intubation in neonates and yo
J Atheroscler Thromb. 2025 Dec 27. doi: 10.5551/jat.65852. Online ahead of print.ABSTRACTAIMS: While glomerular hyperfiltration (GHF) emerged as a risk factor for cardiovascular disease (CVD), little is known about the association between GHF and blood lipid profile. We aimed to examine the associat
Biol Pharm Bull. 2026;49(1):40-46. doi: 10.1248/bpb.b25-00319.ABSTRACTTreatments to improve the prognosis of heart failure with preserved ejection fraction (HFpEF) are urgently needed. Tanshinone VI (TanVI) is a compound extracted from the roots of Salvia miltiorrhiza Bunge (Lamiaceae) that exerts i
We have established a proarrhythmic rabbit model of acute atrioventricular block (AVB) with severe bradycardia to detect delayed rectifier K^(+) channel current (I(Kr)) blocker-induced torsade de pointes (TdP). To better understand the role of β-adrenoceptors in this model, we investigated the effec
Biol Pharm Bull. 2026;49(1):24-29. doi: 10.1248/bpb.b25-00481.ABSTRACTNeuregulin 1 (NRG1), a member of the epidermal growth factor (EGF) family, regulates the development, differentiation, proliferation, and plasticity in multiple tissues through its binding to ErbB3 and ErbB4 receptors. In the card
Biol Pharm Bull. 2026;49(1):1-10. doi: 10.1248/bpb.b25-00628.ABSTRACTAtherosclerosis is a pathological condition that leads to cardiovascular disease and cerebral infarction. Oxidatively modified low-density lipoprotein (LDL), known as oxidized LDL (oxLDL), is one of the major factors for atherogene
Yakugaku Zasshi. 2026;146(1):57-69. doi: 10.1248/yakushi.25-00084.ABSTRACTWhile drugs affecting stroke rehabilitation outcomes have been studied in the context of convalescent hospitals, data on acute stroke patients remain insufficient. This retrospective single-center study aimed to evaluate the i
CONCLUSIONS: Maternal FA supplementation improved cardiac OFT malformations in Tbx1^(neo/neo) embryos by enhancing NCC migration and fate specification, possibly mediated by Notch and Midkine signaling activation. Our findings provide mechanistic insights into the observed reduction in congenital he
Ozanimod hydrochloride (Product name: ZEPOZIA^(®) Capsule Starter Pack, ZEPOZIA^(®) Capsules 0.92 mg; Nonproprietary name: ozanimod hydrochloride, hereinafter referred to as ozanimod) is an orally available receptor modulator that acts on the sphingosine 1-phosphate (S1P) receptor and selectively bi
Am J Clin Nutr. 2026 Jan;123(1):101086. doi: 10.1016/j.ajcnut.2025.10.003. Epub 2025 Dec 9.ABSTRACTBACKGROUND: Blood lipid concentrations are standard clinical biomarkers of cardiovascular disease risk. Replacing dietary saturated fat with unsaturated fat is expected to lower blood lipids. However,
No abstractAm J Clin Nutr. 2026 Jan;123(1):101110. doi: 10.1016/j.ajcnut.2025.10.024. Epub 2025 Nov 27.NO ABSTRACTPMID:41485872 | DOI:10.1016/j.ajcnut.2025.10.024
Am J Clin Nutr. 2026 Jan;123(1):101073. doi: 10.1016/j.ajcnut.2025.09.041. Epub 2025 Nov 27.ABSTRACTBACKGROUND: Public health organizations currently recommend lowering the consumption of sweet-tasting foods, on the assumption that a lower exposure to sweet-tasting foods lowers preferences for sweet
J Am Coll Radiol. 2026 Jan;23(1):159-169. doi: 10.1016/j.jacr.2025.10.029.ABSTRACTSuperior vena cava (SVC) syndrome occurs in approximately 15,000 people in the United States each year. It most commonly occurs secondary to thoracic malignancies, mostly primary lung cancer and lymphoma. The cause is
Am J Obstet Gynecol. 2026 Jan;233(6S):S404-S424. doi: 10.1016/j.ajog.2025.07.055.ABSTRACTVenous thromboembolism contributes to approximately 10% of pregnancy-associated deaths in the United States, with the highest incidence rate in the immediate postpartum period. Cesarean deliveries are associated
Am J Obstet Gynecol. 2026 Jan;233(6S):S272-S279. doi: 10.1016/j.ajog.2025.07.038.ABSTRACTThe incidence of maternal cardiac arrest is rising, paralleling the escalating maternal morbidity and mortality rates in the United States. Effective management of cardiac arrest in pregnancy requires timely ini
