Finding ferritin footprints in 5-fluorouracil-induced cardiotoxicity

Cardiooncology. 2026 Apr 10;12(1):50. doi: 10.1186/s40959-026-00452-8.ABSTRACTFluoropyrimidines, including 5-fluorouracil (5-FU), used in the treatment of patients with gastrointestinal malignancies, are associated with cardiotoxicity. Although the mechanism of this cardiotoxicity remains unknown, r

G Grace M Ferri

Cardiovascular risk prediction in women with gestational diabetes using risk assessment tools: a scoping review

No abstractDiabetol Metab Syndr. 2026 Apr 10. doi: 10.1186/s13098-026-02154-8. Online ahead of print.NO ABSTRACTPMID:41963967 | DOI:10.1186/s13098-026-02154-8

T Tewodros Eshete Wonde

Why hyperinsulinemia is detrimental to weight loss: insights from type 1 diabetes

BMC Med. 2026 Apr 10;24(1):229. doi: 10.1186/s12916-026-04849-1.ABSTRACTBACKGROUND: The global rise in obesity prevalence poses a major health challenge due to its links to hypertension, stroke, type 2 diabetes, cardiovascular disease, depression, and cancer. Effective non-pharmacological strategies

S Stephan Martin

Sarcopenic obesity definitions and their association with cardiovascular disease and mortality

No abstractBMC Geriatr. 2026 Apr 10. doi: 10.1186/s12877-026-07433-7. Online ahead of print.NO ABSTRACTPMID:41963841 | DOI:10.1186/s12877-026-07433-7

Q Qian Xu

Unveiling alternate pathways for SARS-CoV-2 infection via extracellular vesicle-mediated transfer of ACE2 and TMPRSS2

Nat Commun. 2026 Apr 10. doi: 10.1038/s41467-026-71680-w. Online ahead of print.ABSTRACTThe COVID-19 pandemic, caused by SARS-CoV-2, has underscored the urgency of understanding viral entry mechanisms to develop effective therapeutic strategies. SARS-CoV-2 primarily exploits angiotensin-converting e

M Martha Rea-Moreno

Association between atherogenic index of plasma and rapid progression of coronary atherosclerosis in non-diabetic and diabetic adults: Insight from the PARADIGM study

J Cardiovasc Comput Tomogr. 2026 Apr 9:S1934-5925(26)00062-6. doi: 10.1016/j.jcct.2026.03.011. Online ahead of print.ABSTRACTBACKGROUND: Despite a significant association of atherogenic index of plasma (AIP) with plasma atherogenicity as well as insulin resistance and new onset of diabetes, data on

K Ki-Bum Won

Relationship of atherosclerotic lesion by optical coherence tomography with cholesterol efflux capacity by immobilized liposome-bound gel beads method

Atherosclerosis. 2026 Apr 2:120724. doi: 10.1016/j.atherosclerosis.2026.120724. Online ahead of print.ABSTRACTBACKGROUND AND AIMS: Cholesterol efflux capacity (CEC) is robust biomarker for atherosclerotic cardiovascular disease (ASCVD). However, cell-based CEC assays require complex procedures that

T Tsunehiro Miyakoshi

Bariatric surgery reverses blunted blood pressure reactivity to cold-induced stress in patients with severe obesity

Obes Res Clin Pract. 2026 Apr 10:S1871-403X(26)00025-6. doi: 10.1016/j.orcp.2026.03.005. Online ahead of print.ABSTRACTBACKGROUND: Autonomic dysfunction is a pathway linking obesity to cardiovascular disease, contributing to hypertension and impaired pressor control. Individuals with obesity often s

L Leticia Schwambach

Association between cardiometabolic index and high-sensitivity C-reactive protein: A cross-sectional study from National Health and Nutrition Examination Survey 2015 to 2018

J Int Med Res. 2026 Apr;54(4):3000605261436654. doi: 10.1177/03000605261436654. Epub 2026 Apr 10.ABSTRACTObjectiveHigh-sensitivity C-reactive protein, a key inflammatory biomarker, can indicate the risk of cardiovascular diseases. The cardiometabolic index has been associated with metabolic and card

Y Yuhao Yan

A 2-Month-Old Boy With Respiratory Distress, Thrombocytopenia, and an Aggressive Mediastinal Mass

Chest. 2026 Apr;169(4):e135-e141. doi: 10.1016/j.chest.2025.11.006.ABSTRACTA 2-month-old male infant with symptoms of dyspnea and progressive thrombocytopenia was referred to our tertiary care center. Physical examination at the referring hospital revealed tachypnea, head-nodding respiration, and po

T Tong Qiu

Antithrombotic agents: Do they protect from infective endocarditis? A retrospective observational study using TriNetx

Enferm Infecc Microbiol Clin (Engl Ed). 2026 Apr;44(4):503136. doi: 10.1016/j.eimce.2026.503136.ABSTRACTINTRODUCTION: Infective endocarditis (IE) remains a severe infection associated with substantial morbidity and mortality. Given the central role of platelets in its pathogenesis, antithrombotic th

A Alfonso Gotor-Rivera

Efficacy and Safety of preoperative Controlling Heart Rate in Patients with Acute Type A Aortic Dissection (ESCORT): protocol for a randomised controlled trial

BMJ Open. 2026 Apr 10;16(4):e114090. doi: 10.1136/bmjopen-2025-114090.ABSTRACTINTRODUCTION: Aortic dissection (AD) is a life-threatening cardiovascular emergency with a high mortality rate, and acute Stanford Type A AD is the most dangerous form, often requiring surgical intervention. Factors contri

G Guangyu Liu

Peak Oxygen Consumption is Positively Associated with Estimates of Oxygen Extraction and Microvascular Blood Volume in Veterans with Chronic Kidney Disease

Peak oxygen consumption (V̇O(2peak)) is reduced in patients with chronic kidney disease (CKD). Although cardiovascular and skeletal muscle factors are implicated in the declines of VO(2peak), few studies have evaluated muscle oxygenation responses during exercise. We hypothesized that lower VO(2peak

J Jared M Gollie

3-POINT CORRECTION FACTOR IMPROVES ACCURACY OF FRAMINGHAM RISK SCORE IN BREAST CANCER SURVIVORS

Can J Cardiol. 2026 Apr 8:S0828-282X(26)00301-6. doi: 10.1016/j.cjca.2026.03.051. Online ahead of print.ABSTRACTBACKGROUND: After surviving breast cancer (BC), women are at 2-6-fold greater risk of death due to cardiovascular disease (CVD) than women without BC. The Framingham Risk Score (FRS) is an

J Julia N Rickard

Impact of Assisted Reproductive Technologies in Women with Cardiovascular Disease

Can J Cardiol. 2026 Apr 8:S0828-282X(26)00298-9. doi: 10.1016/j.cjca.2026.03.048. Online ahead of print.ABSTRACTBACKGROUND: Assisted reproductive technologies (ART) include medical interventions used to address infertility. As access to ART has expanded globally, more women with underlying cardiovas

A Arya Ardehali

Environmental Pollutant-Induced Cardiopathogenesis Through Immune Dysfunction: The Emerging Role of Micro- and Nanoplastics

Can J Cardiol. 2026 Apr 8:S0828-282X(26)00300-4. doi: 10.1016/j.cjca.2026.03.050. Online ahead of print.ABSTRACTExposure to environmental pollutants and toxicants is increasingly recognized as a major determinant of cardiovascular disease (CVD). Beyond direct toxic effects, these agents profoundly a

R Raffaele Marfella

Real-world weight impact upon tirzepatide discontinuation at a single-center endocrinology clinic in patients with overweight or obesity

J Am Pharm Assoc (2003). 2026 Apr 8:103112. doi: 10.1016/j.japh.2026.103112. Online ahead of print.ABSTRACTBACKGROUND: Overweight and obesity are major contributors to cardiovascular-kidney-metabolic (CKM) disease. Tirzepatide (TZP-MJ), originally approved for type 2 diabetes (T2D), has demonstrated

L Lily Huang

Megacapillaries on nailfold capillaroscopy are associated with white matter hyperintensities burden: a population study

J Stroke Cerebrovasc Dis. 2026 Apr 8:108633. doi: 10.1016/j.jstrokecerebrovasdis.2026.108633. Online ahead of print.ABSTRACTBACKGROUND AND AIMS: White matter hyperintensities (WMH) of presumed vascular origin are reliable neuroimaging markers of cerebral small vessel disease (cSVD). However, their u

O Oscar H Del Brutto

Impact of a multicomponent digital health and telemonitoring intervention on hypertension and diabetes control in cardiac patients: A randomized controlled trial

Indian Heart J. 2026 Apr 8:S0019-4832(26)00044-1. doi: 10.1016/j.ihj.2026.04.005. Online ahead of print.ABSTRACTBACKGROUND: Digital health technologies are promising tools to improve cardiovascular risk factors. We evaluated the impact of a multicomponent digital health program-including a mobile ap

A Arvind Kumar

Quantitative and Spatial Associations of Disability-Populated Areas and Extreme Heat with Stroke Disparities in Chicago

Am J Prev Med. 2026 Apr 8:108362. doi: 10.1016/j.amepre.2026.108362. Online ahead of print.ABSTRACTINTRODUCTION: Compared to individuals without disabilities, people with physical, sensory, intellectual, and psychological disabilities have increased stroke risk and when exposed to extreme heat they

B Babu Gounder

Frequency of a very brief intervention to increase physical activity levels in cardiac rehabilitation attendees: The 'Measure It!' Multicentre randomised trial

Int J Cardiol. 2026 Apr 8:134480. doi: 10.1016/j.ijcard.2026.134480. Online ahead of print.ABSTRACTBACKGROUND: Physical activity levels of cardiac rehabilitation attendees with coronary heart disease (CHD) are low. This study examined whether frequency of physical activity measurement (Measure It!;

N Nicole Freene

When the proteome meets the metabolome observational and Mendelian randomization analyses

Metabolism. 2026 Apr 8:156602. doi: 10.1016/j.metabol.2026.156602. Online ahead of print.ABSTRACTOBJECTIVE: The basis for protein synthesis is the genetic code. Many of these proteins will affect intermediary metabolites by acting as enzymes, hormones, or by other actions. The aim of the present stu

R Rui Zheng

nTargeting PCSK9 suppresses NF-κB-mediated M1 polarization in alveolar macrophages and lung injury induced by low-dose systemic PM2.5 exposure

Toxicol Lett. 2026 Apr 8:111887. doi: 10.1016/j.toxlet.2026.111887. Online ahead of print.ABSTRACTBACKGROUND: Fine particulate matter (PM2.5) exposure is a major environmental risk factor for pulmonary inflammation and injury, in which alveolar macrophages (AMs) play a central role. Proprotein conve

C Chenxi Wang

Sex differences in the relationship between eating window, night eating, and metabolic syndrome risk in emerging adults: Analysis of national health and nutrition examination survey 2017-2020 data

Clin Nutr. 2026 Mar 27;60:106646. doi: 10.1016/j.clnu.2026.106646. Online ahead of print.ABSTRACTBACKGROUND & AIMS: Cardiovascular disease develops throughout life, with metabolic syndrome components increasing risk. Eating patterns - how long individuals eat during a 24-h period and the timing of c

D Diane Vizthum