Curr Opin Lipidol. 2026 Apr 7. doi: 10.1097/MOL.0000000000001040. Online ahead of print.ABSTRACTPURPOSE OF REVIEW: Janus kinase (JAK) inhibitors have emerged as potent anti-inflammatory drugs and are prescribed in rheumatoid arthritis (RA) and inflammatory bowel disease (IBD). However, cardiovascula
No abstractN Engl J Med. 2026 Apr 23;394(16):1658-1659. doi: 10.1056/NEJMc2602103.NO ABSTRACTPMID:42019030 | DOI:10.1056/NEJMc2602103
No abstractN Engl J Med. 2026 Apr 23;394(16):1658. doi: 10.1056/NEJMc2602103.NO ABSTRACTPMID:42019029 | DOI:10.1056/NEJMc2602103
No abstractN Engl J Med. 2026 Apr 23;394(16):1658. doi: 10.1056/NEJMc2602103.NO ABSTRACTPMID:42019028 | DOI:10.1056/NEJMc2602103
No abstractN Engl J Med. 2026 Apr 23;394(16):1657-1658. doi: 10.1056/NEJMc2602103.NO ABSTRACTPMID:42019027 | DOI:10.1056/NEJMc2602103
No abstractN Engl J Med. 2026 Apr 23;394(16):1656-1657. doi: 10.1056/NEJMc2602103.NO ABSTRACTPMID:42019026 | DOI:10.1056/NEJMc2602103
N Engl J Med. 2026 Apr 23;394(16):1571-1582. doi: 10.1056/NEJMoa2515043.ABSTRACTBACKGROUND: Blood-pressure reduction is the only proven treatment to prevent stroke. Whether a single pill that combines three antihypertensive drugs at low doses, in addition to standard antihypertensive treatment, can
Cardiovasc Res. 2026 Apr 22:cvag085. doi: 10.1093/cvr/cvag085. Online ahead of print.ABSTRACTAIMS: Immune checkpoint inhibitors (ICI) have revolutionized cancer treatment. However, their use often leads to cardiovascular adverse effects, including cardiac dysfunction. Here, we hypothesized that a pr
Eur J Prev Cardiol. 2026 Apr 22:zwag232. doi: 10.1093/eurjpc/zwag232. Online ahead of print.ABSTRACTAIMS: Evaluate the prevalence, morphology, and clinical relevance of transient, extreme heart rate (HR) spikes on heart rate monitors (HRMs) in endurance athletes.METHODS: HRM training sessions (n=57,
Neurology. 2026 May 26;106(10):e214985. doi: 10.1212/WNL.0000000000214985. Epub 2026 Apr 22.ABSTRACTBACKGROUND AND OBJECTIVES: Sleep disruption and cognitive impairment are important comorbidities of focal epilepsy. However, the nature to which sleep affects cognition and long-term dementia risk in
Arq Bras Cardiol. 2026 Apr 17;123(2):e20240572. doi: 10.36660/abc.20240572. eCollection 2026.ABSTRACTAcute pericarditis is an inflammation of the pericardium, the lining that surrounds the heart. It is the most common inflammatory heart condition. The disease frequently affects young adults and can
Cien Saude Colet. 2026 Mar;31(3):e11352024. doi: 10.1590/1413-81232026313.11352024. Epub 2025 Apr 15.ABSTRACTThe article discusses the importance of mental health in Primary Health Care (PHC), focusing on the perspective of nurses, in a context of demographic and epidemiological transition in Brazil
Cien Saude Colet. 2026 Mar;31(3):e16742024. doi: 10.1590/1413-81232026313.16742024. Epub 2024 Nov 7.ABSTRACTThe Adequate Childbirth Project (Projeto Parto Adequado - PPA) is an initiative by the National Supplementary Health Agency aimed at reducing the occurrence of cesarean sections in private hos
Cien Saude Colet. 2026 Mar;31(3):e06662024. doi: 10.1590/1413-81232026313.06662024. Epub 2024 Dec 4.ABSTRACTWe aimed to explore the association between lifestyle, sociodemographic variables, and multimorbidity, as well as to identify the patterns of multimorbidity (dyads). Cross-sectional study, bas
Rev Assoc Med Bras (1992). 2026 Apr 20;72(2):e20251054. doi: 10.1590/1806-9282.20251054. eCollection 2026.ABSTRACTOBJECTIVE: The aim of this study was to evaluate the levels of nuclear factor erythroid 2 related factor 2, tumor necrosis factor alpha, interleukin-40, and endorepellin in patients unde
Rev Bras Epidemiol. 2026 Apr 20;29:e260019. doi: 10.1590/1980-549720260019.2. eCollection 2026.ABSTRACTOBJECTIVE: To analyze sociodemographic determinants associated with medical care before death from heart failure (HF) in Mexico, comparing 2019 and 2023.METHODS: A retrospective cross-sectional ana
Braz J Med Biol Res. 2026 Apr 17;59:e14744. doi: 10.1590/1414-431X2026e14744. eCollection 2026.ABSTRACTThe introduction of combination antiretroviral therapy (cART) has significantly reduced AIDS-related morbidity and mortality. However, the prevalence of age-associated comorbidities, particularly c
Arq Bras Cardiol. 2026 Mar;123(3):e20250712. doi: 10.36660/abc.20250712.ABSTRACTHeart failure (HF) is among the leading causes of cardiovascular mortality in Brazil. In 2021, costs attributable to HF exceeded R$ 22 billion in the Brazilian Unified Health System (SUS). The incorporation of new therap
J Sex Med. 2026 Apr 9;23(5):qdag056. doi: 10.1093/jsxmed/qdag056.ABSTRACTBACKGROUND: Erectile dysfunction (ED) is a multifactorial condition and an early indicator of systemic vascular dysfunction. Although obesity is a major modifiable risk factor for ED, the longitudinal impact of body mass index
Am J Hypertens. 2026 Apr 22:hpag033. doi: 10.1093/ajh/hpag033. Online ahead of print.ABSTRACTBACKGROUND: HEARTS in the Americas is the regional adaptation of the WHO Global HEARTS Initiative. This paper presents Phase 3 of HEARTS 2.0, an evidence-informed process to prioritize clinical and health-sy
Cardiol Rev. 2026 Apr 22. doi: 10.1097/CRD.0000000000001273. Online ahead of print.ABSTRACTDextrocardia occurs in approximately 1 in 10,000 live births and is frequently dismissed as an incidental anatomic variant, particularly when accompanied by situs inversus totalis and a structurally normal hea
Eur J Prev Cardiol. 2026 Apr 22:zwag158. doi: 10.1093/eurjpc/zwag158. Online ahead of print.ABSTRACTAIMS: Concomitant aortic stenosis (AS) and cardiac amyloidosis (CA) result in heart failure and reduced life expectancy. Early detection of CA in AS is an unmet clinical need to prevent disease progre
Sci Transl Med. 2026 Apr 22;18(846):eadu3761. doi: 10.1126/scitranslmed.adu3761. Epub 2026 Apr 22.ABSTRACTDiabetes mellitus (DM) accelerates vascular diseases including peripheral arterial disease (PAD). Endothelial cells (ECs) and macrophages (MΦs) are important contributors to DM-associated vascul
Reprogrammed TREM2^(+) macrophages drive nonresolving inflammation in peripheral artery disease associated with type 2 diabetes (Malhi et al., this issue).Sci Transl Med. 2026 Apr 22;18(846):eaef8756. doi: 10.1126/scitranslmed.aef8756. Epub 2026 Apr 22.ABSTRACTReprogrammed TREM2+ macrophages drive n
