Efficacy and safety of baxdrostat add-on in uncontrolled and resistant hypertension: a systematic review and meta-analysis of randomized controlled trials with GRADE certainty-of-evidence assessment

Naunyn Schmiedebergs Arch Pharmacol. 2026 Jul 22. doi: 10.1007/s00210-026-05660-8. Online ahead of print.ABSTRACTUncontrolled and resistant hypertension continues to be a significant contributor to cardiovascular and renal risk. Baxdrostat is a selective aldosterone synthase inhibitor which has demo

M Mahmoud Elsayed

Emerging Clinical Concepts in Pain Management of Ehlers-Danlos Syndrome

Curr Pain Headache Rep. 2026 Jul 22;30(1):92. doi: 10.1007/s11916-026-01532-1.ABSTRACTPURPOSE OF REVIEW: Ehlers-Danlos syndrome (EDS) is a congenital connective tissue disorder that is often marked by chronic pain and considerable functional impairment. Pain in EDS is typically multifaceted, involvi

R Rohan C Banerjee

Refining the Role of Beta-Blockers in Cardiovascular Medicine

J Am Coll Cardiol. 2026 Jul 15:S0735-1097(26)06835-X. doi: 10.1016/j.jacc.2026.06.015. Online ahead of print.ABSTRACTBeta-blockers have long been a foundational pharmacotherapy in cardiovascular care across many disease conditions. However, the emergence of contemporary randomized trials and large p

B Brett W Sperry