Effects of intravenous furosemide plus small-volume hypertonic saline solutions on inflammatory, remodelling markers and epigenetics signatures of patients with congestive acute decompensated heart failure (ADHF)

Aging (Albany NY). 2026 Mar 26;18(1):190-212. doi: 10.18632/aging.206364. Epub 2026 Mar 26.ABSTRACTAIMS: In a randomised controlled trial (RCT), we compared the effects of treatment with furosemide + small volumes of hypertonic saline solution (HSS) with those of furosemide alone in patients with de

M Mario Daidone

ADAMTS and ADAMTSL mutations in connective tissue disorders

Physiology (Bethesda). 2026 Mar 31. doi: 10.1152/physiol.00043.2025. Online ahead of print.ABSTRACTThe ADAMTS family are extracellular matrix (ECM) proteins and enzymes involved in regulating tissue structure and function. The ECM is a network of proteins and polysaccharides surrounding the cells th

A Ana D Alcocer

Haemostatic changes during CART cell therapy and risk of complications

Cancer Immunol Immunother. 2026 Mar 31;75(4):130. doi: 10.1007/s00262-026-04371-6.ABSTRACTChimeric antigen receptor T cell (CART) therapy toxicity includes cytokine release syndrome (CRS), immune effector cell-associated neurotoxicity syndrome (ICANS), but also thrombotic and haemorrhagic events. Gi

M María Panizo-Inogés