Curr Top Med Chem. 2026 Jul 26. doi: 10.2174/0115680266466273260722130035. Online ahead of print.ABSTRACTPeroxisome proliferator-activated receptors (PPARs) are nuclear receptors that regulate metabolic homeostasis and represent important therapeutic targets for conditions such as type 2 diabetes, d
Circ Res. 2026 Jul 29. doi: 10.1161/CIRCRESAHA.125.327192. Online ahead of print.ABSTRACTBACKGROUND: Despite optimal glycemic control, the heart failure burden remains substantial in diabetic patients. Metabolic remodeling is involved in this process, yet our current understanding is still in its in
Eur J Heart Fail. 2026 Jul 29:xuag240. doi: 10.1093/ejhf/xuag240. Online ahead of print.ABSTRACTBACKGROUND: Exercise training improves exercise tolerance (peak oxygen consumption, peakV̇O2) in patients with heart failure with preserved ejection fraction (HFpEF), but it remains unclear whether the ef
Circ Res. 2026 Jul 29. doi: 10.1161/CIRCRESAHA.125.327491. Online ahead of print.ABSTRACTBACKGROUND: Chronic inflammation is a key driver of atherosclerotic cardiovascular disease. Notably, anti-inflammatory therapies have demonstrated efficacy in reducing cardiac events. We previously reported that
Clin Cardiol. 2026 Aug;49(8):e70429. doi: 10.1002/clc.70429.ABSTRACTBACKGROUND: Cardiovascular disease (CVD) risk assessment based on single-time-point measurements may inadequately capture the dynamic interplay of obesity, metabolic dysfunction, and chronic inflammation. Understanding their long-te
Acta Obstet Gynecol Scand. 2026 Jul 29. doi: 10.1111/aogs.70322. Online ahead of print.ABSTRACTINTRODUCTION: Preeclampsia is known to be associated with a two- to fourfold elevated risk of developing cardiovascular disease in the first 15 years following pregnancy. In this cross-sectional study of 8
G Ital Cardiol (Rome). 2026 Aug;27(8):551-558. doi: 10.1714/4741.47566.ABSTRACTBACKGROUND: Cardiogenic shock is a critical condition with a short-term mortality rate of around 40-50%, which has remained unchanged over the years despite therapeutic advances in acute cardiac diseases. In this context,
Hum Vaccin Immunother. 2026 Dec;22(1):2697144. doi: 10.1080/21645515.2026.2697144. Epub 2026 Jul 29.ABSTRACTEvidence suggests that a substantial part of influenza-related morbidity and mortality is due to cardiovascular events. Limited population-level evidence exists regarding whether seasonal infl
Curr Pharm Des. 2026 Jul 25. doi: 10.2174/0113816128456434260713163014. Online ahead of print.ABSTRACTINTRODUCTION: Insulin resistance and type 2 diabetes mellitus (T2DM) are serious worldwide health issues linked to dyslipidaemia, oxidative stress, impaired glucose metabolism, and persistent inflam
Stem Cells Transl Med. 2026 Jul 20;15(8):szag049. doi: 10.1093/stcltm/szag049.ABSTRACTPURPOSE: Recent research indicates that the senescence of bone marrow mesenchymal stem cells (BMSCs) disrupts the osteo-adipogenic balance, a primary factor contributing to the development of osteoporosis. Our prev
Asian J Androl. 2026 Jul 28. doi: 10.4103/aja202614. Online ahead of print.ABSTRACTThere are rising concerns regarding the cardiovascular diseases associated with androgen deprivation therapy (ADT) for prostate cancer (PCa). This study aims to investigate the relationship between the dynamic changes
J Hosp Med. 2026 Jul 28. doi: 10.1002/jhm.70412. Online ahead of print.ABSTRACTBACKGROUND: Infective endocarditis (IE) related to opioid use disorder (OUD) and injection substance use is on the rise. Multidisciplinary care is recommended for individuals with substance-related IE, but little is known
Clin J Am Soc Nephrol. 2026 Jul 24. doi: 10.2215/CJN.0000001195. Online ahead of print.ABSTRACTPivotal clinical trials have heralded several new classes of pharmacological agents focused on improving combined heart-kidney outcomes among patients with cardiovascular-kidney-metabolic syndrome. This re
Angiology. 2026 Jul 28:33197261474644. doi: 10.1177/00033197261474644. Online ahead of print.ABSTRACTStable angina pectoris is a common manifestation of chronic coronary syndrome, and simple physical examination findings may provide additional information for cardiovascular risk assessment. This stu
S D Med. 2026 Feb;79(2):76-78.ABSTRACTDanon disease (DD) is a rare X-linked dominant lysosomal storage disorder caused by mutations in the LAMP2 gene. It is typically characterized by a triad of intellectual disability, skeletal myopathy, and cardiomyopathy. Due to the X-linked inheritance pattern,
Alzheimers Dement. 2026 Aug;22(8):e71567. doi: 10.1002/alz.71567.ABSTRACTINTRODUCTION: Dementia clinical risk scores (CRSs) provide accessible tools for identifying individuals at risk for Alzheimer's disease (AD) and related dementias, yet their performance across diverse populations and relationsh
Cardiovasc Diabetol. 2026 Jul 28;25(1):212. doi: 10.1186/s12933-026-03312-y.ABSTRACTBACKGROUND: Copeptin, a surrogate marker for vasopressin secretion, is associated with cardiovascular disease, insulin resistance and dysglycaemia. The cardioprotective effects of sodium-glucose cotransporter 2 inhib
BMC Cardiovasc Disord. 2026 Jul 28;26(1):641. doi: 10.1186/s12872-026-06078-z.ABSTRACTBACKGROUND: The diagnosis of pulmonary hypertension (PH) relies primarily on invasive right heart catheterization (RHC). Although imaging modalities, including echocardiography, computed tomography angiography (CTA
Clin Rheumatol. 2026 Jul 28. doi: 10.1007/s10067-026-08324-3. Online ahead of print.ABSTRACTINTRODUCTION: Physical activity (PA) may play an important role as a non-pharmacological addition to the management of SLE for disease control and reduction of cardiovascular risk factors. Those with SLE have
Intern Emerg Med. 2026 Jul 28. doi: 10.1007/s11739-026-04456-1. Online ahead of print.ABSTRACTThe epidemiology of hepatocellular carcinoma (HCC) is increasingly shaped by the expanding burden of type 2 diabetes (T2D), obesity, and metabolic dysfunction-associated steatotic liver disease (MASLD). Glu
Geroscience. 2026 Jul 28. doi: 10.1007/s11357-026-02439-w. Online ahead of print.ABSTRACTAlthough individual social determinants of health (SDoH) are known to influence non-alcoholic fatty liver disease (NAFLD) outcomes, the cumulative effect of comprehensive SDoH exposure and the underlying biologi
Biol Trace Elem Res. 2026 Jul 29. doi: 10.1007/s12011-026-05262-8. Online ahead of print.ABSTRACTThe zinc-to-copper ratio (ZCR) reflects essential metal balance and may be relevant to cardiovascular regulation, yet its association with hypertension in populations exposed to environmental heavy metal
Eur Radiol. 2026 Jul 28. doi: 10.1007/s00330-026-12778-z. Online ahead of print.ABSTRACTBACKGROUND: Pericoronary adipose tissue (PCAT) reflects local coronary inflammation and microstructural changes and may predict major adverse cardiac events (MACE). Radiomics extracts high-dimensional features fr
Nat Biomed Eng. 2026 Jul 28. doi: 10.1038/s41551-026-01745-0. Online ahead of print.ABSTRACTSpatial transcriptomics has transformed tissue analysis but remains constrained by high cost, complex workflows, sequencing dependence and limited access to post-transcriptional regulation in fresh tissues. H
