J Intern Med. 2026 Mar 26. doi: 10.1111/joim.70087. Online ahead of print.ABSTRACTINTRODUCTION: Hyperkalaemia is a serious complication in patients with chronic kidney disease (CKD) and heart failure (HF), often leading to the discontinuation of renin-angiotensin-aldosterone system inhibitors (RAASi
Eur Heart J. 2026 Mar 26:ehag162. doi: 10.1093/eurheartj/ehag162. Online ahead of print.ABSTRACTBACKGROUND AND AIMS: While the prevalence, drivers, and impact of cardiometabolic risk factors are known to differ between women and men, less is known about sex differences in the cardiovascular-kidney-m
Fundam Clin Pharmacol. 2026 May;40(3):e70078. doi: 10.1111/fcp.70078.ABSTRACTBACKGROUND: The soluble guanylate cyclase (sGC)/GMPc pathway plays an important in pulmonary arterial hypertension (PAH).OBJECTIVE: We investigated whether trans-4-methoxy-β-nitrostyrene (T4MN), a novel sGC stimulator, prev
Circ Cardiovasc Interv. 2026 Mar 26:e016269. doi: 10.1161/CIRCINTERVENTIONS.125.016269. Online ahead of print.ABSTRACTBACKGROUND: The impact of proportionality to heart valve regurgitation has been widely investigated in mitral regurgitation, helping to better characterize the best candidates for th
Arterioscler Thromb Vasc Biol. 2026 Mar 26. doi: 10.1161/ATVBAHA.125.324125. Online ahead of print.ABSTRACTBACKGROUND: Knowledge of proteomic mechanisms explaining the link between psychosocial stress and cardiovascular disease is limited. This study aimed to (1) identify plasma proteins associated
Arterioscler Thromb Vasc Biol. 2026 Mar 26. doi: 10.1161/ATVBAHA.125.322869. Online ahead of print.ABSTRACTGetting healthy sleep was recognized in 2022 by the American Heart Association as a key health behavior of Life's Essential 8 based on growing evidence of its impact on cardiovascular health. A
Hypertension. 2026 Mar 26. doi: 10.1161/HYPERTENSIONAHA.125.25507. Online ahead of print.ABSTRACTBACKGROUND: Bilateral macronodular adrenocortical disease is often linked to autonomous cortisol secretion, but may also present with primary aldosteronism (PA).METHODS: This international (Europe, Unite
Circulation. 2026 Mar 26. doi: 10.1161/CIR.0000000000001419. Online ahead of print.ABSTRACTAmbient temperature is a key environmental driver of cardiovascular health. With rising global temperatures and increasing frequency, intensity, and duration of extreme temperature events, understanding the ca
Prog Rehabil Med. 2026 Mar 25;11:20260012. doi: 10.2490/prm.20260012. eCollection 2026.ABSTRACTOBJECTIVES: Cachexia is a condition marked by weight loss and reduced skeletal muscle mass, with or without the loss of fat mass, commonly occurring in patients with chronic diseases such as cancer and hea
Front Immunol. 2026 Mar 10;17:1769874. doi: 10.3389/fimmu.2026.1769874. eCollection 2026.ABSTRACTINTRODUCTION: Obstructive Sleep Apnea (OSA) is a prevalent syndrome characterized by intermittent hypoxemia and elevated risk of comorbidities, including cancer. In this context, the immune response may
Front Immunol. 2026 Mar 10;17:1761519. doi: 10.3389/fimmu.2026.1761519. eCollection 2026.ABSTRACTBehçet's Syndrome (BS) is a systemic vasculitis characterized by variable vessel involvement and an elusive etiology, though immunogenetic studies strongly implicate the IL-23/IL-17 axis which bridges in
Front Immunol. 2026 Mar 10;17:1747560. doi: 10.3389/fimmu.2026.1747560. eCollection 2026.ABSTRACTBACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) continues to pose a significant clinical challenge due to its high mortality rate and limited treatment efficacy. The role of disulfidptosis, a recentl
Am Heart J Plus. 2026 Mar 7;64:100742. doi: 10.1016/j.ahjo.2026.100742. eCollection 2026 Apr.ABSTRACTBACKGROUND: Cardiovascular-kidney-metabolic (CKM) syndrome is a novel staging construct that reflects the pathophysiological interplay between these individual conditions. The long-term trends in the
Indian J Dermatol. 2026 Mar-Apr;71(2):120-126. doi: 10.4103/ijd.ijd_836_24. Epub 2026 Feb 27.ABSTRACTINTRODUCTION: Atopic dermatitis (AD) is a chronic and recurrent inflammatory disease that begins in childhood and can persist into adulthood, with a significant impact on quality of life. However, th
Front Aging Neurosci. 2026 Mar 10;18:1741339. doi: 10.3389/fnagi.2026.1741339. eCollection 2026.ABSTRACTINTRODUCTION: Alzheimer's disease (AD) is the most common form of dementia, characterized by progressive memory decline, with neuropathological hallmarks including amyloid plaques and neurofibrill
Front Cardiovasc Med. 2026 Mar 10;13:1726544. doi: 10.3389/fcvm.2026.1726544. eCollection 2026.ABSTRACTBACKGROUND: Pathogenic variants in the X-linked USP9X gene, which evades X-chromosome inactivation, have been predominantly linked to neurodevelopmental disorders (NDDs). Accumulating evidence has
Front Cardiovasc Med. 2026 Mar 10;13:1722107. doi: 10.3389/fcvm.2026.1722107. eCollection 2026.ABSTRACTINTRODUCTION: Statins are the cornerstone of secondary prevention in atherosclerotic cardiovascular disease (ASCVD), but their association with new-onset diabetes mellitus (NODM) remains incomplete
Front Cardiovasc Med. 2026 Mar 10;13:1757348. doi: 10.3389/fcvm.2026.1757348. eCollection 2026.ABSTRACTThere are a large number of people suffer from metabolic, cardiovascular, and cerebrovascular diseases, posing a significant threat to public health. Previous studies have suggested that cardiovasc
No abstractFront Cardiovasc Med. 2026 Mar 10;13:1792721. doi: 10.3389/fcvm.2026.1792721. eCollection 2026.NO ABSTRACTPMID:41884634 | PMC:PMC13008622 | DOI:10.3389/fcvm.2026.1792721
Front Cell Infect Microbiol. 2026 Mar 10;16:1717419. doi: 10.3389/fcimb.2026.1717419. eCollection 2026.ABSTRACTBACKGROUND: Healthcare-associated infections due to carbapenem-resistant Klebsiella pneumoniae (CRKP) are a global public health threat with rising hospital morbidity and mortality. We cond
Drug Des Devel Ther. 2026 Feb 3;20:521070. doi: 10.2147/DDDT.S521070. eCollection 2026.ABSTRACTPURPOSE: To develop a population pharmacokinetics (PPK) model for polymyxin B (PB) in critically ill patients, and propose individualized dosing regimens.METHODS: Blood samples were collected from intensiv
Drug Des Devel Ther. 2026 Feb 3;20:583837. doi: 10.2147/DDDT.S583837. eCollection 2026.ABSTRACTDiabetic macular edema (DME) remains a leading cause of vision loss in the working-age population, yet its management is undergoing a fundamental paradigm shift from high-frequency anti-VEGF monotherapy to
Front Neurol. 2026 Mar 10;17:1778854. doi: 10.3389/fneur.2026.1778854. eCollection 2026.ABSTRACTBACKGROUND: Obstructive sleep apnea syndrome (OSAS) is a common sleep-related breathing disorder associated with significant cardiovascular, metabolic, and neuropsychological consequences. Increasing evid
Ther Adv Endocrinol Metab. 2026 Mar 23;17:20420188261431021. doi: 10.1177/20420188261431021. eCollection 2026.ABSTRACTBACKGROUND: The WATCH-DM integer-based risk score (WATCH-DM(i)) was originally developed and validated to predict heart failure (HF) hospitalization risk in patients with type 2 diab
