J Diabetes. 2025 Dec;17(12):e70173. doi: 10.1111/1753-0407.70173.ABSTRACTThe recurrence of diabetic foot ulcers (DFUs) brings significant morbidity to people with diabetes and adds to healthcare costs. According to current guidelines, a DFU is considered healed when it is re-epithelialized, and the
Health Informatics J. 2025 Oct-Dec;31(4):14604582251401411. doi: 10.1177/14604582251401411. Epub 2025 Nov 28.ABSTRACTObjective: Atrial fibrillation (AF) is the most common sustained arrhythmia in clinical practice and is associated with an elevated risk of stroke, heart failure, dementia, and mortal
Can Liver J. 2025 Sep 11;8(3):448-459. doi: 10.3138/canlivj-2025-0010. eCollection 2025 Sep.ABSTRACTBACKGROUND: Liver transplantation is a life-saving treatment for end-stage liver disease, significantly improving survival. In Canada, the number of liver transplants has increased, with British Colum
J Inflamm Res. 2025 Nov 21;18:16365-16383. doi: 10.2147/JIR.S547634. eCollection 2025.ABSTRACTBACKGROUND: Kawasaki disease (KD) is a systemic vasculitis predominantly affecting children under five years old, with coronary artery lesions (CALs) being a severe complication. Despite the effectiveness o
Front Med (Lausanne). 2025 Nov 12;12:1691897. doi: 10.3389/fmed.2025.1691897. eCollection 2025.ABSTRACTBACKGROUND: Pemphigus vulgaris (PV) is a rare but potentially life-threatening autoimmune blistering disease. Rituximab has recently gained prominence as a first-line treatment for moderate-to-seve
Vasc Health Risk Manag. 2025 Nov 22;21:949-964. doi: 10.2147/VHRM.S555592. eCollection 2025.ABSTRACTCerebrovascular diseases (CVDs) impose a heavy global health burden, necessitating efficient management strategies. Artificial intelligence (AI) has become a key transformative tool across the CVD car
Eur Heart J Imaging Methods Pract. 2025 Nov 24;3(4):qyaf143. doi: 10.1093/ehjimp/qyaf143. eCollection 2025 Oct.ABSTRACTAIMS: Fungal infective endocarditis (IE) is known to carry high morbidity and mortality, yet contemporary literature on the imaging features and prognosis of this patient population
Biomed Res Int. 2025 Nov 26;2025:8076503. doi: 10.1155/bmri/8076503. eCollection 2025.ABSTRACTPatients with hypertension may be more susceptible to acquiring Staphylococcus aureus (S. aureus) infections, according to some studies. Hypertension and certain antihypertensive drugs predispose to multidr
Transpl Int. 2025 Nov 12;38:15091. doi: 10.3389/ti.2025.15091. eCollection 2025.ABSTRACTIslet transplantation is a valuable therapy for selected type 1 diabetes mellitus (T1DM) patients, especially those with recurrent severe hypoglycemia, glycemic variability, or impaired hypoglycemia awareness. It
J Heart Valve Soc. 2025 Apr-Jun;2(2):182-197. Epub 2025 Jun 25.ABSTRACTMitral annular calcification (MAC) is an inflammatory process that shares characteristics with atherosclerosis and results in calcium deposition in the fibrous ring supporting the mitral valve. It is commonly encountered at older
Nat Sci Sleep. 2025 Nov 22;17:3033-3051. doi: 10.2147/NSS.S549883. eCollection 2025.ABSTRACTObstructive Sleep Apnea Syndrome (OSAS) is a prevalent sleep disorder characterized by recurrent upper airway obstruction, resulting in intermittent hypoxia, oxidative stress, and systemic inflammation. Ferro
Front Oncol. 2025 Nov 12;15:1701639. doi: 10.3389/fonc.2025.1701639. eCollection 2025.ABSTRACTCarfilzomib, a second-generation proteasome inhibitor, is approved for the treatment of relapsed or refractory multiple myeloma, with cardiovascular toxicity being the most common concern. Nevertheless, pul
J Arrhythm. 2025 Nov 25;41(6):e70232. doi: 10.1002/joa3.70232. eCollection 2025 Dec.ABSTRACTBACKGROUND: Atrial fibrillation (AF), the most frequently occurring sustained arrhythmia in patients with hypertrophic cardiomyopathy (HCM), is linked to poor quality of life and increased thromboembolic risk
Front Physiol. 2025 Nov 12;16:1700313. doi: 10.3389/fphys.2025.1700313. eCollection 2025.ABSTRACTHypertrophic cardiomyopathy (HCM) is a prevalent hereditary cardiovascular disease that affects individuals worldwide. While current treatments have improved the prognosis for many patients, HCM continue
Prog Pediatr Cardiol. 2020 Jun;57:101185. doi: 10.1016/j.ppedcard.2019.101185. Epub 2020 Jun 8.ABSTRACTNeurodevelopmental disabilities are common sequelae of congenital heart disease, particularly cognitive impairments that impede academic achievement. Cognitive training has been shown to be effecti
EPMA J. 2025 Oct 28;16(4):805-817. doi: 10.1007/s13167-025-00425-4. eCollection 2025 Dec.ABSTRACTOBJECTIVE: Atherosclerosis and chronic kidney disease are major contributors to cardiovascular disease (CVD) and premature mortality worldwide. However, how kidney function decline and carotid plaque (CP
EPMA J. 2025 Oct 15;16(4):785-804. doi: 10.1007/s13167-025-00427-2. eCollection 2025 Dec.ABSTRACTBACKGROUND: Hypertension, a major modifiable risk factor for cardiovascular disease, exhibits significant heterogeneity due to genetic, metabolic, and environmental influences. Traditional one-size-fits-
EPMA J. 2025 Sep 29;16(4):857-908. doi: 10.1007/s13167-025-00424-5. eCollection 2025 Dec.ABSTRACTBACKGROUND: Non-communicable diseases (NCDs), including cardiovascular diseases, respiratory disorders, And age-related degenerative diseases, account for 74% of global mortality, imposing heavy burdens
EPMA J. 2025 Sep 28;16(4):773-783. doi: 10.1007/s13167-025-00421-8. eCollection 2025 Dec.ABSTRACTOBJECTIVE: Hypertension management remains challenging due to coexisting insulin resistance (IR) and arterial stiffness-two silent yet synergistic drivers of atherosclerotic cardiovascular disease (ASCVD
Front Endocrinol (Lausanne). 2025 Nov 12;16:1697718. doi: 10.3389/fendo.2025.1697718. eCollection 2025.ABSTRACTAIMS: This study aims to investigate the relationship between the neutrophil-to-lymphocyte (NLR) and the risk of sudden cardiac death (SCD) in the patients with diabetic foot ulcer (DFU).ME
Front Bioeng Biotechnol. 2025 Nov 12;13:1615863. doi: 10.3389/fbioe.2025.1615863. eCollection 2025.ABSTRACTOBJECTIVE: This study aimed to develop a poly (lactic-co-glycolic acid) (PLGA)-based magnetic loaded iron oxide (Fe3O4) and single-chain urokinase-type plasminogen activator (proUK) for enhanci
Front Pharmacol. 2025 Nov 12;16:1678846. doi: 10.3389/fphar.2025.1678846. eCollection 2025.ABSTRACTINTRODUCTION: Chronic kidney disease (CKD) often leads to renal anemia, a complication traditionally treated with erythropoiesis-stimulating agents (ESAs) and iron supplementation. However, these treat
Front Nutr. 2025 Nov 12;12:1699166. doi: 10.3389/fnut.2025.1699166. eCollection 2025.ABSTRACTBACKGROUND: The quality of fat in food affects the cardiovascular system by means of inflammatory and lipid pathways.OBJECTIVE: To assess the relationship among middle-aged persons' cardiovascular disease (C
Front Nutr. 2025 Nov 12;12:1622952. doi: 10.3389/fnut.2025.1622952. eCollection 2025.ABSTRACTHigh cholesterol is one of the risk factors for cardiovascular disease, which is currently a global health problem. This study aimed to compare the potential of tempe flour and soybean flour as functional fo
