Ultrasmall Cu2-xSe nanoparticles alleviate vascular calcification through inhibiting oxidative stress and NF-κB/NLRP3-mediated inflammation

Redox Biol. 2025 Dec 3;89:103961. doi: 10.1016/j.redox.2025.103961. Online ahead of print.ABSTRACTVascular calcification, prevalent in patients with chronic kidney disease, atherosclerosis, and diabetes, is strongly associated with elevated cardiovascular morbidity and mortality, highlighting the ur

D Ding Liu

The triglyceride-glucose index and mortality in chronic kidney and cardiovascular disease patients: A cohort study

Diab Vasc Dis Res. 2025 Nov-Dec;22(6):14791641251407680. doi: 10.1177/14791641251407680. Epub 2025 Dec 7.ABSTRACTBackgroundChronic kidney disease (CKD) comorbid with cardiovascular disease (CVD) results in substantial mortality. The predictive value of the triglyceride-glucose (TyG) index for mortal

Y Yuying Hou

Endothelial LRRC8A mitigates pressure overload-induced cardiac hypertrophy by promoting coronary angiogenesis

Angiogenesis. 2025 Dec 7;29(1):7. doi: 10.1007/s10456-025-10021-9.ABSTRACTOBJECTIVE: Clinical evidence has indicated that pressure overload-induced cardiac hypertrophy is closely linked with adverse cardiac outcomes. Endothelial dysfunction is a key contributor to the progression of cardiac hypertro

L Lingjun Jie

Correction to the Article "Pediatric Sarcopenia: What do We Know?"

Acta Med Port. 2025 Dec 2;38(12):842-848. doi: 10.20344/amp.24225. Epub 2025 Dec 2.ABSTRACTPediatric sarcopenia is an emerging health issue that affects muscle development, strength, and overall well-being in children and adolescents. While it was initially linked to aging, recent studies highlight

M Marília Marques

Uric Acid, BMI, and Neutrophil Lymphocyte Ratio Mediate the Relationship Between Soft Drink Consumption and Systolic Blood Pressure: A Nationwide Structural Equation Model Pathways Among Adolescents and Young Adults Across Indonesia

Biol Res Nurs. 2025 Dec 7:10998004251406291. doi: 10.1177/10998004251406291. Online ahead of print.ABSTRACTBackground: Adolescent hypertension is an emerging global issue, with metabolic and inflammatory dysregulation potentially preceding cardiovascular disease. Increasing soft drinks and fast food

M Maria Dyah Kurniasari

Campfire Smoke as a Plausible Trigger for Vasospastic Angina: Insights From a Case Report

Am J Case Rep. 2025 Dec 7;26:e949363. doi: 10.12659/AJCR.949363.ABSTRACTBACKGROUND Vasospastic angina (Prinzmetal angina) has been linked to many risk factors, including tobacco smoking. Although numerous studies have reported associations between air pollutants and cardiovascular outcomes, the rela

G Gabrielle Denault

Aortic root replacement versus preservation in acute type A aortic dissection repair: meta-analysis of reconstructed time-to-event data

J Cardiothorac Surg. 2025 Dec 6;20(1):452. doi: 10.1186/s13019-025-03718-x.ABSTRACTBACKGROUND: Outcomes of aortic root replacement (ARR) versus conservative root approach (CRA) in patients undergoing acute type A aortic dissection (ATAAD) repair remained controversy.METHODS: The present study was a

Y Yiran Zhang

Construction and validation of a risk predictive model for fear of disease progression in patients after percutaneous coronary intervention

Sci Rep. 2025 Dec 6. doi: 10.1038/s41598-025-31099-7. Online ahead of print.ABSTRACTThis study aimed to construct and validate a predictive model for fear of disease progression in patients after percutaneous coronary intervention(PCI). From March to October 2024, 455 post-PCI patients in the Depart

Y Yuxin Li

Fatty acid-binding protein 5 aggravates psoriasis and psoriasis-like disease through ferroptosis

Cell Death Differ. 2025 Dec 6. doi: 10.1038/s41418-025-01630-4. Online ahead of print.ABSTRACTPsoriasis (Ps) is a chronic inflammatory skin disease with systemic manifestations, such as psoriatic arthritis (PsA), cardiovascular and psychiatric complications, and subsequent negative effects on patien

K Kamil Mieczkowski

Association between changes in Chinese visceral adiposity index and cardiovascular disease among middle-aged and older Chinese adults

Sci Rep. 2025 Dec 6. doi: 10.1038/s41598-025-31561-6. Online ahead of print.ABSTRACTPrevious studies have established visceral adiposity as a risk factor for cardiovascular disease (CVD), but the relationship between longitudinal changes in Chinese Visceral Adiposity Index (CVAI) and CVD risk has no

L Li-Hua Huang

The association between tooth loss and serum cholesterol levels in adults: a scoping review

BMC Oral Health. 2025 Dec 6. doi: 10.1186/s12903-025-07431-y. Online ahead of print.ABSTRACTOBJECTIVE: This scoping review systematically mapped the evidence on the association between tooth loss and serum cholesterol levels in adults, addressing a significant gap in understanding the direct link be

K Keyi Wan

Cyclophilin B deficiency enhances myocardial energy synthesis and protects against heart failure in preclinical models

BMC Med. 2025 Dec 7. doi: 10.1186/s12916-025-04563-4. Online ahead of print.ABSTRACTBACKGROUND: Heart failure (HF) represents the end stage of cardiovascular diseases with high mortality and limited treatment options. Cyclophilin B (CypB), known mainly as an endoplasmic reticulum chaperone, has been

X Xiao Zong

Survival impact of anti-CD38-based quadruplet regimens in transplant-ineligible newly diagnosed multiple myeloma: a network meta-analysis and reconstructed individual patient data meta-analysis

Blood Cancer J. 2025 Dec 6;15(1):212. doi: 10.1038/s41408-025-01413-7.ABSTRACTFrontline therapy for transplant-ineligible newly diagnosed multiple myeloma (TI-NDMM) has advanced with anti-CD38 monoclonal antibody (mAb)-based regimens. Although quadruplet combinations incorporating daratumumab and is

J João Tadeu Damian Souto Filho

Protective effects of biomimetic Cu-Zn-MOF against DOX-Induced cardiotoxicity through inhibiting oxidative stress and ferroptosis

J Nanobiotechnology. 2025 Dec 6. doi: 10.1186/s12951-025-03902-0. Online ahead of print.ABSTRACTBACKGROUND: Doxorubicin (DOX), a member of the anthracycline family, is widely recognized as an effective chemotherapeutic agent for cancer treatment. However, its clinical application is limited due to i

J Jian Wang

Androgen deprivation therapy with apalutamide in the treatment of metastatic castration-sensitive prostate cancer: the systematic review of its effectiveness and applicability for Asian men in the targeted investigational treatment analysis of novel anti-androgen (TITAN) trial

Int Urol Nephrol. 2025 Dec 6. doi: 10.1007/s11255-025-04943-y. Online ahead of print.ABSTRACTBACKGROUND: The TITAN trial established survival benefits of adding apalutamide to androgen deprivation therapy (ADT) in metastatic castration‑sensitive prostate cancer (mCSPC). Whether efficacy and safety a

F Fan Yang

Time-updated FIB-4 index predicts coronary artery calcification progression in individuals with metabolic dysfunction-associated steatotic liver disease

Sci Rep. 2025 Dec 6. doi: 10.1038/s41598-025-31289-3. Online ahead of print.ABSTRACTMetabolic dysfunction-associated steatotic liver disease (MASLD) is the most common chronic liver disorder worldwide and is increasingly recognized as a multisystem disease that elevates cardiovascular disease (CVD)

Y Yesung Lee

Impact of bariatric surgery on metabolic-dysfunction associated fatty liver disease in diabetic and non-diabetic patients: a cohort study

No abstractBMC Gastroenterol. 2025 Dec 7. doi: 10.1186/s12876-025-04524-4. Online ahead of print.NO ABSTRACTPMID:41353247 | DOI:10.1186/s12876-025-04524-4

M Mohammad Sistanizad

Real-world study to compare functional SYNTAX score versus anatomical SYNTAX score in influencing the treatment strategy for multivessel disease patients

Sci Rep. 2025 Dec 6. doi: 10.1038/s41598-025-30804-w. Online ahead of print.ABSTRACTThere are limited prospective clinical studies that use the functional SYNTAX score (FSS) to determine treatment strategies, as compared to the anatomical SYNTAX score (ASS), in patients with multivessel disease (MVD

N Nattawut Wongpraparut

Proteome-wide association study of prostate cancer risk across populations

Nat Commun. 2025 Dec 6. doi: 10.1038/s41467-025-66250-5. Online ahead of print.ABSTRACTThere is insufficient understanding of the molecular basis of prostate cancer (PCa) across different populations. We perform a large-scale proteome-wide association study (PWAS) to identify proteins with genetical

H Hua Zhong

Autophagy and mitophagy in dermatological disease: a comprehensive review from molecular pathways to therapeutic frontiers

Biol Direct. 2025 Dec 6. doi: 10.1186/s13062-025-00703-1. Online ahead of print.ABSTRACTAutophagy - the cell's built-in recycling and quality-control programme - touches every layer of cutaneous biology. In keratinocytes it sculpts the cornified envelope; in melanocytes it balances pigment synthesis

L Luca D'Ambrosio

Independent and combined effects of mean blood glucose and glycemic variability on 28-day mortality in older acute myocardial infarction patients: a MIMIC-IV cohort study

No abstractBMC Geriatr. 2025 Dec 6. doi: 10.1186/s12877-025-06499-z. Online ahead of print.NO ABSTRACTPMID:41353156 | DOI:10.1186/s12877-025-06499-z

J Jun Zhou

The rs34416841 polymorphism in the Alu element of the circSirt1 flanking intron is associated with an increased risk of myocardial infarction

BMC Med Genomics. 2025 Dec 6. doi: 10.1186/s12920-025-02291-5. Online ahead of print.ABSTRACTBACKGROUND: circSirt1 can ameliorate neointimal hyperplasia and provide protection against atherosclerosis. Single nucleotide polymorphisms (SNPs) in circRNA flanking introns, particularly within Alu element

Y Yu-Lan Zhou

Succinate-GPR91 signaling promotes cardiomyocyte metabolic reprogramming and NAD+ production to alleviate HFpEF

Cardiovasc Diabetol. 2025 Dec 6. doi: 10.1186/s12933-025-03030-x. Online ahead of print.ABSTRACTBACKGROUND: Disrupted cardiomyocyte energy metabolism is a hallmark of heart failure with preserved ejection fraction (HFpEF). Succinate, a key intermediate of the tricarboxylic acid cycle, is markedly de

Y Yumeng Jia

Weight-adjusted waist index outperforms other obesity indices for cardiovascular disease prediction in cardiovascular-kidney-metabolic syndrome: insights from UK biobank

BMC Public Health. 2025 Dec 7. doi: 10.1186/s12889-025-25830-2. Online ahead of print.ABSTRACTBACKGROUND: Cardiovascular-kidney-metabolic (CKM) syndrome, a systemic disorder often initiated by adipose tissue dysfunction, is an emerging concept for integrated risk assessment. Although the link betwee

T Tianyu Wang