Cologne (Germany): Institute for Quality and Efficiency in Health Care (IQWiG); 2026 Feb 22.ABSTRACTRESEARCH QUESTION: The aim of this report is toassess the benefit of diagnostics using cardiac magnetic resonance imaging as part of a diagnostic strategy, compared with a diagnostic strategy without
Natl Med J India. 2026 Jan-Feb;39(1):13-18. doi: 10.25259/NMJI_827_2022.ABSTRACTBackground Chronic kidney disease (CKD) is associated with accelerated cardiovascular (CV) risk, particularly due to subclinical atherosclerosis. Carotid intima-media thickness (CIMT) is a non-invasive marker of early at
Natl Med J India. 2025 Sep-Oct;38(5):268-274. doi: 10.25259/NMJI_878_2023.ABSTRACTBackground We aimed to evaluate the efficacy and safety of anticoagulant therapy, especially direct oral anticoagulant (DOAC) therapy, for primary prevention of venous thromboembolism (VTE), including deep vein thrombo
Liver Int. 2026 Mar;46(3):e70546. doi: 10.1111/liv.70546.ABSTRACTBACKGROUND AND AIMS: The aging of liver donors and transplant candidates, along with the growing prevalence of metabolic comorbidities, may lead to hepatic artery atherosclerosis. Since the biliary epithelium relies on arterial flow, h
Circ Genom Precis Med. 2026 Feb 6:e005361. doi: 10.1161/CIRCGEN.125.005361. Online ahead of print.ABSTRACTBACKGROUND: Cardiac involvement is the main determinant of adverse outcomes in Fabry disease. The study aimed to investigate cardiovascular outcomes in patients with Fabry disease.METHODS: This
Circulation. 2026 Feb 6. doi: 10.1161/CIRCULATIONAHA.125.074752. Online ahead of print.ABSTRACTBACKGROUND: Bicuspid aortic valve (BAV) is a frequent congenital heart defect with a high heritability. Despite this, only a limited number of genes have been associated with the disease, and the molecular
Circulation. 2026 Feb 6. doi: 10.1161/CIRCULATIONAHA.125.074797. Online ahead of print.ABSTRACTBACKGROUND: No large registries of patients with acute eosinophilic myocarditis (EM) are available. However, EM is perceived as a cardiac disease with high mortality, affecting mainly young and middle-aged
CONCLUSIONS: TRPM7-mediated intracellular Zn²^(+) release contributes to myocardial I/R injury by triggering apoptotic and pyroptotic cardiomyocyte death. Given that TRPM7 is highly upregulated in patients with ischemic heart failure, our findings suggest that targeting TRPM7 may represent a novel t
Circulation. 2026 Feb 6. doi: 10.1161/CIRCULATIONAHA.124.072850. Online ahead of print.ABSTRACTBACKGROUND: End-stage heart failure (HF) remains a major global health challenge, and left ventricular assist devices (LVADs) represent an important therapeutic option. LVAD-mediated mechanical unloading i
Hypertension. 2026 Feb 6. doi: 10.1161/HYPERTENSIONAHA.125.26228. Online ahead of print.ABSTRACTFewer than 2% of eligible patients are screened for primary aldosteronism, despite evidence that early detection and targeted therapy are associated with lower cardiovascular and kidney morbidity. Recent
Acta Oncol. 2026 Feb 6;65:66-74. doi: 10.2340/1651-226X.2026.43885.ABSTRACTBACKGROUND AND PURPOSE: Radiotherapy (RT) is a key treatment for locally advanced non-small cell lung cancer (NSCLC). Tumours near the heart may result in unintended cardiac radiation exposure, increasing the risk of cardioto
Redox Rep. 2026 Dec;31(1):2624946. doi: 10.1080/13510002.2026.2624946. Epub 2026 Feb 6.ABSTRACTOBJECTIVES: Reperfusion, an essential therapeutic strategy for salvaging ischemic myocardium in ischemic heart disease, paradoxically exacerbates myocardial injury. Ferroptosis is a pivotal mechanism under
Redox Rep. 2026 Dec;31(1):2622255. doi: 10.1080/13510002.2026.2622255. Epub 2026 Feb 6.ABSTRACTOBJECTIVES: Urolithin A (UA) is a natural polyphenolic compound produced by gut bacteria. Vascular remodeling contributes to hypertension, and vascular smooth muscle cells (VSMCs) proliferation and migrati
J Ultrasound Med. 2026 Feb 6. doi: 10.1002/jum.70195. Online ahead of print.ABSTRACTGout, a prevalent and treatable form of crystal-induced arthritis, results from monosodium urate (MSU) crystal deposition in articular and periarticular tissues. Early diagnosis is crucial to prevent progression to c
Age Ageing. 2026 Feb 1;55(2):afag016. doi: 10.1093/ageing/afag016.ABSTRACTBACKGROUND: Primary care services play a key role in dementia care, yet activity may vary between subtypes.OBJECTIVE: To investigate longitudinal determinants of primary care contact across Alzheimer's disease (ad), vascular d
Int J Mol Med. 2026 Apr;57(4):85. doi: 10.3892/ijmm.2026.5756. Epub 2026 Feb 6.ABSTRACTDonation after circulatory death (DCD) is a key source of liver grafts but it is associated with more severe ischemia‑reperfusion injury (IRI) and poorer transplant outcomes compared with donation after brain deat
Int J Mol Med. 2026 Apr;57(4):82. doi: 10.3892/ijmm.2026.5753. Epub 2026 Feb 6.ABSTRACTDiabetic cardiomyopathy (DCM) is a significant complication in patients with diabetes, but its pathogenesis is not fully understood. In recent years, dynamic regulation of lipid droplets (LDs) balance has graduall
Mol Med Rep. 2026 Apr;33(4):106. doi: 10.3892/mmr.2026.13816. Epub 2026 Feb 6.ABSTRACTCardiovascular diseases (CVDs) remain the primary cause of death worldwide. Exploring novel therapeutic targets is important for defining future research directions in cardiovascular medicine. Considering the notab
Int J Mol Med. 2026 Apr;57(4):87. doi: 10.3892/ijmm.2026.5758. Epub 2026 Feb 6.ABSTRACTSepsis‑induced vasoplegia, a life‑threatening complication of sepsis, has become a focal point of research endeavors aimed at determining its complex mechanisms. However, existing investigations predominantly focu
Mol Med Rep. 2026 Apr;33(4):110. doi: 10.3892/mmr.2026.13820. Epub 2026 Feb 6.ABSTRACTTruncated‑cadherin (T‑cadherin) is a distinct glycosylphosphatidylinositol‑anchored atypical cadherin that differs from classical cadherins since it does not have transmembrane and intracellular domains. It primari
J Hypertens. 2026 Jan 23. doi: 10.1097/HJH.0000000000004248. Online ahead of print.ABSTRACTAIM: To investigate sex differences in the use of antihypertensive therapy and achievement of blood pressure targets among patients with hypertension in a real-world clinical setting.METHODS: Data were used fr
Angew Chem Int Ed Engl. 2026 Feb 5:e25690. doi: 10.1002/anie.202525690. Online ahead of print.ABSTRACTCovalent organic frameworks (COFs) featuring desirable redox-active sites have become competitive cathode materials for aqueous zinc-organic batteries (ZOBs). However, multi-active COFs, albeit with
Clin Cardiol. 2026 Feb;49(2):e70269. doi: 10.1002/clc.70269.ABSTRACTOBJECTIVE: Hypertension is a key risk factor for aortic dissection (AD). AD, if left untreated, carries significant mortality rates. Our aim is to analyse trends in mortality due to AD in adults with primary hypertension in the Unit
J Hypertens. 2026 Feb 3. doi: 10.1097/HJH.0000000000004260. Online ahead of print.ABSTRACTINTRODUCTION: Sleep duration is associated with blood pressure (BP), the leading risk factor for cardiovascular disease. Yet, limited data exists on the relationship between objectively measured sleep duration
