Peripheral Artery Disease in the Legs

N Engl J Med. 2026 Jan 29;394(5):486-496. doi: 10.1056/NEJMcp2501200.ABSTRACTPeripheral artery disease affects approximately 236 million persons worldwide and is diagnosed with an ankle-brachial index of less than 0.90. Among older persons, 3.3% of those without peripheral artery disease, 18.1% with

M Mary M McDermott

A Randomized Trial of Tenecteplase in Acute Central Retinal Artery Occlusion

N Engl J Med. 2026 Jan 29;394(5):442-450. doi: 10.1056/NEJMoa2508515.ABSTRACTBACKGROUND: Central retinal artery occlusion can result in permanent vision loss. Effective treatment is lacking.METHODS: We conducted a phase 3, double-blind, double-dummy, randomized, controlled trial involving adults wit

S Stephen J Ryan