The role of transposable elements activity in genomic instability and their relationship to aging process

Cell Cycle. 2026 Jan 18:1-33. doi: 10.1080/15384101.2025.2611968. Online ahead of print.ABSTRACTTransposable elements (TEs) are mobile DNA sequences capable of self-replication (especially retrotransposons) within the genome, which may lead to various forms of DNA damage. The introduction of this re

J Jingran Hu

Weight-independent effects of dietary carbohydrate-to-fat ratio on metabolomic profiles: secondary outcomes of a 5-month randomized controlled feeding trial

Nat Commun. 2026 Jan 17. doi: 10.1038/s41467-026-68353-z. Online ahead of print.ABSTRACTDiet plays a crucial role in health, with low-carbohydrate diets often proposed to exert metabolic benefits. We aim to investigate metabolomic adaptations in 164 adults with overweight or obesity who were randoml

A Angeliki M Angelidi

Association of cholesterol, high-density lipoprotein and glucose (CHG) index with mortality risk in metabolic dysfunction-associated steatotic liver disease (MASLD) adults: results from two prospective cohorts

No abstractCardiovasc Diabetol. 2026 Jan 17. doi: 10.1186/s12933-026-03079-2. Online ahead of print.NO ABSTRACTPMID:41547820 | DOI:10.1186/s12933-026-03079-2

H Huangxin Zhu

Nationwide outcomes of cardiac surgery in patients with cannabis use disorder

J Cardiothorac Surg. 2026 Jan 17. doi: 10.1186/s13019-025-03755-6. Online ahead of print.ABSTRACTOBJECTIVE: To characterize in-hospital morbidity and mortality in patients undergoing cardiovascular surgery with and without cannabis use disorder (CUD) using a national database.METHODS: Between 2016 a

K Krish C Dewan

Metabolic score for visceral fat profiles and incident cardiovascular disease in adults with CKM syndrome stages 0-3: a CHARLS longitudinal study

BMC Cardiovasc Disord. 2026 Jan 17. doi: 10.1186/s12872-026-05511-7. Online ahead of print.ABSTRACTBACKGROUND: The Metabolic Score for Visceral Fat (METS-VF) is a novel index reflecting visceral adiposity and metabolic dysfunction, but its association with incident cardiovascular disease (CVD) in ad

H Hao Zhang

Epigenetic age deceleration reflects exercise-induced cardiorespiratory fitness improvements

Geroscience. 2026 Jan 17. doi: 10.1007/s11357-025-02076-9. Online ahead of print.ABSTRACTEpigenetic clocks are emerging as promising biomarkers of biological aging, yet their sensitivity to short-term interventions remains unclear. This pilot study investigates whether the GrimAge clock can capture

M Menno Van Damme

Artificial intelligence and precision medicine

No abstractSci Rep. 2026 Jan 17;16(1):2186. doi: 10.1038/s41598-026-35404-w.NO ABSTRACTPMID:41547658 | DOI:10.1038/s41598-026-35404-w

Z Zeeashan Ahmed

SGLT-2 inhibitors and GLP-1 receptor agonists in primary care pharmacotherapy of type 2 diabetes in people living with HIV versus HIV-negative controls: Findings from a multicenter study in Germany

Prim Care Diabetes. 2026 Jan 16:S1751-9918(26)00005-7. doi: 10.1016/j.pcd.2026.01.005. Online ahead of print.ABSTRACTAIMS: Sodium-glucose cotransporter-2 inhibitors (SGLT-2i) and glucagon-like peptide-1 receptor agonists (GLP-1 RA) improve glycemic control and reduce cardiovascular (CV) mortality. H

L L Hilgefort

Exploring nutritional indicators of cardiovascular mortality risk in elderly hypertensive patients: The long-term predictive advantage of PNI

Nutr Metab Cardiovasc Dis. 2025 Dec 19:104531. doi: 10.1016/j.numecd.2025.104531. Online ahead of print.ABSTRACTBACKGROUND AND AIMS: Cardiovascular mortality is the leading cause of death among elderly hypertensive patients. However, the reference indicators for nutritional management in this popula

S Sheng-Han Wang

Synergistic impact of insulin resistance and hepatic fibrosis on cardiovascular events in patients with coronary artery disease: A machine learning subtyping and interaction analysis

Nutr Metab Cardiovasc Dis. 2025 Dec 13:104520. doi: 10.1016/j.numecd.2025.104520. Online ahead of print.ABSTRACTBACKGROUND AND AIMS: Insulin resistance (IR) and hepatic fibrosis are significant yet underexplored synergistic risk factors for cardiovascular events in coronary artery disease (CAD). We

Z Zhihao Zheng

Corrigendum to: Dual role of microglia in neuroinflammation and neurodegenerative diseases. [Neurobiology of Disease, Volume 216, November 2025, 107133]

No abstractNeurobiol Dis. 2026 Jan 16:107276. doi: 10.1016/j.nbd.2026.107276. Online ahead of print.NO ABSTRACTPMID:41547593 | DOI:10.1016/j.nbd.2026.107276

A Amir Ajoolabady

Unlocking the anti-aging potential of Lycium barbarum polysaccharides: Structure-activity insights, mechanisms, and future therapeutics

Int J Biol Macromol. 2026 Jan 15:150242. doi: 10.1016/j.ijbiomac.2026.150242. Online ahead of print.ABSTRACTAging is a time-dependent biological process characterized by degenerative changes in the body, influenced by genetics, environment, and dietary habits. Lycium barbarum polysaccharides (LBPs)

J Juntao Zhang

Transcatheter closure versus antithrombotic therapy for cryptogenic stroke in elderly patients with patent foramen ovale: a systematic review and meta-analysis of non-randomized studies

J Stroke Cerebrovasc Dis. 2026 Jan 15:108562. doi: 10.1016/j.jstrokecerebrovasdis.2026.108562. Online ahead of print.ABSTRACTBACKGROUND: There is lacking of robust clinical evidence comparing transcatheter closure with antithrombotic therapy in elderly patent foramen ovale (PFO) patients with crypto

Y Yang Dong

Medial arterial calcification of the foot arteries is associated with incident cardiovascular events or all-cause mortality in patients with diabetes-related foot ulceration

Diabetes Res Clin Pract. 2026 Jan 15:113108. doi: 10.1016/j.diabres.2026.113108. Online ahead of print.ABSTRACTAIMS: Pedal medial arterial calcification (pMAC) is a marker of vascular pathology incidentally detected on foot x-ray. We assessed the association between pMAC and major adverse cardiovasc

N Nick S R Lan

Rora Regulates Hematopoietic Stem Cell Phenotypes and Progression of Chronic Myelogenous Leukemia

Am J Pathol. 2026 Jan 15:S0002-9440(26)00004-0. doi: 10.1016/j.ajpath.2025.12.010. Online ahead of print.ABSTRACTHematopoietic stem cell (HSC) aging leads to hematological dysfunction and diseases, but the regulatory factors involved remain incompletely characterized. In this study, HasCATs model wa

N Ning Li

Confounders, diagnostic accuracy and reproducibility in CMR-feature tracking derived left atrial strain: A BER-CMR multi-software, multi-site comparison

J Cardiovasc Magn Reson. 2026 Jan 15:102692. doi: 10.1016/j.jocmr.2026.102692. Online ahead of print.ABSTRACTAIMS: Cardiovascular Magnetic Resonance-feature tracking (CMR-FT) derived left atrial global longitudinal strain (LA-GLS) has prognostic relevance, even in the early stages of cardiovascular

L Leo Dyke Krüger

Extracellular volume fraction associates with long-term outcome in patients with severe symptomatic aortic stenosis: 10-year outcomes of the RELIEF-AS Study

J Cardiovasc Magn Reson. 2026 Jan 15:102689. doi: 10.1016/j.jocmr.2026.102689. Online ahead of print.ABSTRACTAIMS: Diffuse fibrosis is central to the pathophysiology of aortic stenosis (AS), can be assessed using cardiovascular magnetic resonance (CMR) with extracellular volume fraction (ECV%), and

N Nikoo Aziminia

Lycopene Protects Against Myocardial Ischemia-Reperfusion Injury by Inhibiting FABP3-Mediated Pyroptosis in Cardiac Microvascular Endothelial Cells

J Nutr Biochem. 2026 Jan 15:110270. doi: 10.1016/j.jnutbio.2026.110270. Online ahead of print.ABSTRACTCardiac microvascular damage exhibits a significant association with myocardial ischemia/reperfusion injury (MI/RI) development, which correlates with mitochondrial dysfunction. Lycopene has demonst

Y Yuetong Sha

Cell Membrane-Coated Nanoparticles Target Multiorgan Crosstalk in Cardiovascular-Kidney-Metabolic Syndrome

Acta Biomater. 2026 Jan 15:S1742-7061(26)00037-1. doi: 10.1016/j.actbio.2026.01.029. Online ahead of print.ABSTRACTCardiovascular-Kidney-Metabolic (CKM) syndrome is a complex, integrated disorder marked by metabolic dysregulation that drives interorgan crosstalk through inflammatory, oxidative, and

J Junyan Zhang

Psychometric properties of health-related quality of life patient reported outcome measures for common cardiovascular conditions: a scoping review and COSMIN analysis

Eur J Cardiovasc Nurs. 2026 Jan 18:zvaf217. doi: 10.1093/eurjcn/zvaf217. Online ahead of print.ABSTRACTAIMS: Health-related quality of life (HRQoL) is an important measure of disease status and represents a holistic approach to delivering patient-centered care. We conducted a scoping review of HRQoL

A Asad Bhatty

Glucagon-like receptor agonists and next-generation incretin-based medications: metabolic, cardiovascular, and renal benefits

Lancet. 2026 Jan 14:S0140-6736(25)02105-1. doi: 10.1016/S0140-6736(25)02105-1. Online ahead of print.ABSTRACTGLP-1 receptor agonists were initially developed to treat type 2 diabetes and have had a transformative effect on its therapy, and are highly effective for glycaemic control, with the added b

M Michael A Nauck

Delivery plan in cardio-obstetric management of pregnant patients with heart disease: an Italian Delphi study

Eur J Obstet Gynecol Reprod Biol. 2026 Jan 12;318:114958. doi: 10.1016/j.ejogrb.2026.114958. Online ahead of print.ABSTRACTBACKGROUND: Cardiovascular disease (CVD) is the leading indirect cause of maternal morbidity and mortality in high-income countries. Managing pregnant women with cardiac conditi

E Elena Zaccone

Sleep apnoea and its consequences: from animal models to precision medicine

Sleep Med. 2026 Jan 8;140:108777. doi: 10.1016/j.sleep.2026.108777. Online ahead of print.ABSTRACTA European Respiratory Society research seminar entitled "Sleep Apnoea and Its Consequences: From Animal Models to Precision Medicine" was held in January 2024 in Lisbon, Portugal. It provided an in-dep

R Raphael Heinzer

Multimodal exercise prescription for frail older adults with cardiovascular disease: A safe and effective approach to enhance physical function and quality of life

Geriatr Nurs. 2026 Jan 16;68:103803. doi: 10.1016/j.gerinurse.2026.103803. Online ahead of print.ABSTRACTThis study developed and evaluated a multimodal exercise prescription for older adults with cardiovascular disease (CVD) and frailty to improve physical function and quality of life. A six-month

L Li Liu