Drug-induced sleep endoscopy-defined upper-airway collapse phenotypes and the presence of cardiometabolic comorbidity in adults with obstructive sleep apnea: A single-center retrospective cross-sectional study

J Int Med Res. 2026 Sep;54(9):3000605261480899. doi: 10.1177/03000605261480899. Epub 2026 Sep 28.ABSTRACTObjectiveTo evaluate whether upper-airway collapse phenotypes recorded during drug-induced sleep endoscopy were associated with the presence of cardiometabolic comorbidity in adults with polysomn

W Wei-Hung Chang

Beyond waste: arginine metabolism and ammonium detoxification in cardiovascular-renal-metabolic disease

Trends Endocrinol Metab. 2026 Sep 28:S1043-2760(26)00244-4. doi: 10.1016/j.tem.2026.09.005. Online ahead of print.ABSTRACTAmmonium is a toxic product of amino acid degradation and protein turnover that is incorporated into arginine and detoxified via the urea cycle. Recent work has expanded the role

L Lauren Peysakhova

Nonspecific ECG Abnormalities in Syncope: Causal Mechanism or Incidental Finding?

Heart Lung. 2026 Sep 28:102957. doi: 10.1016/j.hrtlng.2026.102957. Online ahead of print.ABSTRACTNonspecific electrocardiographic (ECG) abnormalities are common in patients presenting with syncope, but their presence does not necessarily establish the mechanism of transient loss of consciousness. Th

M Maria Giulia Bellicini

Mortality and risk factors associated with death in patients with obesity hypoventilation syndrome and of predominantly Afro-Caribbean origin in Martinique

BMJ Open Respir Res. 2026 Sep 28;13(1):e003819. doi: 10.1136/bmjresp-2025-003819.ABSTRACTBACKGROUND: Obesity hypoventilation syndrome (OHS) is a respiratory complication of obesity. Mortality from OHS is non-negligible. Risk factors for OHS-related mortality are not well established and vary in the

M Moustapha Agossou

Economic evaluation of NT-proBNP testing plus standard clinical assessment versus standard clinical assessment alone for the prevention of heart failure in older adults with type 2 diabetes

BMJ Open Diabetes Res Care. 2026 Sep 28;14(5):e006304. doi: 10.1136/bmjdrc-2026-006304.ABSTRACTINTRODUCTION: N-terminal pro-B-type natriuretic peptide (NT-proBNP) testing for early heart failure (HF) detection in asymptomatic older adults with diabetes in the USA remains limited despite guideline re

J James L Januzzi

LIRA-Guided Supra-Annular Sizing for TAVR in Bicuspid Aortic Valve Disease: Reproducible, But Is it Enough?

No abstractJACC Cardiovasc Interv. 2026 Sep 28;19(18):2512-2514. doi: 10.1016/j.jcin.2026.07.003.NO ABSTRACTPMID:42805722 | DOI:10.1016/j.jcin.2026.07.003

W Won-Keun Kim

Clinical Performance and Reproducibility of the LIRA Method for TAVR in Bicuspid Anatomy: The SUBLIME Study

JACC Cardiovasc Interv. 2026 Sep 28;19(18):2501-2511. doi: 10.1016/j.jcin.2026.06.018.ABSTRACTBACKGROUND: Transcatheter aortic valve replacement (TAVR) in bicuspid aortic valve (BAV) anatomy remains challenging, with heterogeneous outcomes and no standardized sizing strategy. The LIRA (level of impl

B Barbara Bellini

Transcatheter Patent Ductus Arteriosus Closure in Extremely Premature Infants: Transition to the Bedside

JACC Cardiovasc Interv. 2026 Sep 28;19(18):2490-2500. doi: 10.1016/j.jcin.2026.05.040.ABSTRACTBACKGROUND: Extremely premature infants (<28 weeks' gestation) with hemodynamically significant patent ductus arteriosus (PDA) may require transcatheter PDA closure (TCPC) when medical therapy fails. Althou

S Shyam Sathanandam

Residual Mitral Regurgitation as a Long-Term Predictor of Mortality After Mitral TEER

JACC Cardiovasc Interv. 2026 Sep 28;19(18):2474-2486. doi: 10.1016/j.jcin.2026.06.034.ABSTRACTBACKGROUND: The MITRA-PRO registry revealed residual mitral regurgitation (MR) as an important predictor of 1-year and 3-year mortality following mitral transcatheter edge-to-edge repair (M-TEER).OBJECTIVES

D Dennis Rottländer

Stenting Technique and Clinical Outcome in True Bifurcation PCI: Insights From the OCTOBER Trial

JACC Cardiovasc Interv. 2026 Sep 28;19(18):2444-2454. doi: 10.1016/j.jcin.2026.06.027.ABSTRACTBACKGROUND: Optimal stenting for true coronary bifurcation lesions is widely debated, with few studies using predefined intracoronary imaging.OBJECTIVES: The aim of this study was to assess predictors and o

L Lene Dohn Andreasen

Efficacy and Safety of Incremental Hemodialysis: A Systematic Review and Meta-Analysis

Semin Dial. 2026 Sep 28. doi: 10.1111/sdi.70048. Online ahead of print.ABSTRACTHemodialysis, the most commonly employed renal replacement therapy in end-stage kidney disease, prescriptions have long been standardized as thrice-weekly at full-dose; however, HD implementation is not without major comp

B Berk Mizrak

Development of a framework to improve the quality and value of choosing outcomes in cardiovascular disease research (FAVOUR): a study protocol

BMJ Open. 2026 Sep 28;16(9):e119104. doi: 10.1136/bmjopen-2026-119104.ABSTRACTBACKGROUND: Selecting appropriate outcomes is crucial for enhancing the comparability and relevance of clinical trials, yet uptake of core outcome sets (COS) remains low. This study aims to develop a framework to improve t

R Ruijin Qiu

Bleeding complications after percutaneous coronary intervention of CTO lesions versus non-CTO lesions: a prospective observational study from the South-East Netherlands Heart Registration (ZON-HR)

BMJ Open. 2026 Sep 28;16(9):e119900. doi: 10.1136/bmjopen-2026-119900.ABSTRACTBACKGROUND: Chronic total occlusion (CTO) percutaneous coronary intervention (PCI) is known for higher adverse event rates compared with non-CTO PCI. Comparative outcomes with respect to bleeding events remain limited.OBJE

A Alexander M Griffioen

Abemaciclib and lenalidomide presenting with central retinal artery occlusion in a patient with breast cancer and multiple myeloma: a possible treatment-related association

BMJ Case Rep. 2026 Sep 28;19(9):e271351. doi: 10.1136/bcr-2025-271351.ABSTRACTCentral retinal artery occlusion (CRAO) is a vision-threatening vascular emergency that often causes permanent monocular visual loss. We report a woman in her late seventies with metastatic hormone receptor-positive, HER2-

M Manas Pustake

Jejunal transection caused by postoperative adhesive small bowel obstruction: managed simultaneously with abdominal aortic aneurysm

BMJ Case Rep. 2026 Sep 28;19(9):e272236. doi: 10.1136/bcr-2026-272236.ABSTRACTA man in his 90s presented with abdominal pain and was referred to our hospital. Contrast-enhanced CT revealed an abdominal aortic aneurysm (AAA) without evidence of rupture and marked dilatation of the small bowel, leadin

K Kimiya Maemura

Immune responses following myocardial infarction in aged mice

J Mol Cell Cardiol. 2026 Sep 28:S0022-2828(26)00153-7. doi: 10.1016/j.yjmcc.2026.09.008. Online ahead of print.ABSTRACTAging is a major risk factor for cardiovascular diseases and is often accompanied by systemic alterations of the immune system, such as the accumulation of terminally differentiated

E Ebram Tharwat Melika

Safety profile of Finerenone: Pooled analysis of different types of arrhythmic events

J Cardiol. 2026 Sep 28:S0914-5087(26)00189-9. doi: 10.1016/j.jjcc.2026.09.008. Online ahead of print.ABSTRACTBACKGROUND: Finerenone reduces kidney and cardiovascular events in patients with chronic kidney disease and type 2 diabetes mellitus, but its safety profile in terms of arrhythmic outcomes re

G George Bazoukis

EASL-EASD-EASO Guidance for the Use of Resmetirom and Semaglutide as MASH-Targeted Therapy

J Hepatol. 2026 Dec 1:S0168-8278(26)02877-1. doi: 10.1016/j.jhep.2026.08.028. Online ahead of print.ABSTRACTAdults with metabolic dysfunction-associated steatotic liver disease (MASLD) and steatohepatitis (MASH) are at risk for cardiometabolic complications and major adverse liver-related outcomes (

E European Association for the Study of the Liver (EASL). Electronic address:

Global prevalence and clinical implications of coronary artery dominance: A meta-analysis

Hellenic J Cardiol. 2026 Sep 28:S1109-9666(26)00162-4. doi: 10.1016/j.hjc.2026.09.001. Online ahead of print.ABSTRACTBACKGROUND: Coronary artery dominance (CD) influences myocardial perfusion, collateral vessel development, and cardiovascular outcomes. However, reported prevalence estimates vary acr

G George Triantafyllou

Associations of IDL cholesterol and LDL alpha-tocopherol with diabetic kidney disease in type 2 diabetes

Diabetes Res Clin Pract. 2026 Sep 28:113571. doi: 10.1016/j.diabres.2026.113571. Online ahead of print.ABSTRACTAIMS: Patients with type 2 diabetes mellitus (T2DM) commonly exhibit atherogenic dyslipidemia and increased oxidative stress, which may contribute to the development and progression of diab

Y Yuji Hirowatari

Proteomic Profiling of Post-COVID -19 Sequelae

Mol Cell Proteomics. 2026 Sep 28:101670. doi: 10.1016/j.mcpro.2026.101670. Online ahead of print.ABSTRACTThe emergence of Post-COVID sequelae (PCS) represents a global challenge. However, understanding of biological mechanisms and the definition of quantifiable risk factors remains limited. This stu

S Sepehr Golriz Khatami

Study protocol for The Heart Watch Study - Prognostic performance of smartwatch 12-lead ECG with advanced ECG analysis in consumer self-screening for cardiovascular disease

Am Heart J. 2026 Sep 29:107619. doi: 10.1016/j.ahj.2026.107619. Online ahead of print.ABSTRACTBACKGROUND: It is now possible to acquire a fully diagnostic standard 12-lead electrocardiography (ECG) using a smartwatch, a smartphone app, and no additional hardware. This study aims to evaluate the pred

Z Zaidon S Al-Falahi

Prevalence of Sarcomeric Hypertrophic Cardiomyopathy in 31,325 Consecutive Forensic Autopsies from Portugal

Cardiovasc Pathol. 2026 Sep 28:107865. doi: 10.1016/j.carpath.2026.107865. Online ahead of print.ABSTRACTBACKGROUND: Hypertrophic cardiomyopathy (HCM) is the most common monogenic cardiac disorder, with an estimated prevalence of approximately 0.2%. Its clinical expression is highly variable, rangin

L Laura Martins

Decoding obstructive sleep apnea phenotypes through integrated multimodal sleep EEG

Neurobiol Dis. 2026 Sep 28:107631. doi: 10.1016/j.nbd.2026.107631. Online ahead of print.ABSTRACTObstructive sleep apnea (OSA) is a heterogeneous disorder poorly characterized by the apnea-hypopnea index (AHI), with current subtyping overlooking sleep neurophysiology. We aimed to identify objective

J Junxiao Zheng