Gpx4 Deletion-Mediated Macrophage Ferroptosis Alleviates Obesity-Associated Insulin Resistance

FASEB J. 2026 Jan 31;40(2):e71427. doi: 10.1096/fj.202503596R.ABSTRACTObesity has become a global epidemic and a major contributor to the development of Type 2 diabetes (T2D) through the promotion of insulin resistance. Emerging evidence has shown that GPX4 expression is reduced in macrophages under

S Suhua Wu

Cardiac Sympathetic Innervation and Ventricular Arrhythmias in Structural Heart Disease: Current Peripheral Neuromodulation Therapies and Emerging Therapeutic Targets

Arrhythm Electrophysiol Rev. 2025 Dec 22;14:e34. doi: 10.15420/aer.2025.24. eCollection 2025.ABSTRACTOver the past several decades, substantial evidence has pointed to the role of the autonomic nervous system in the genesis and maintenance of ventricular arrhythmia. In particular, sympathetic activa

L Léa Benabou

The Beneficial Effects of Glucagon-Like Peptide-1 Agonists on Blood Pressure: A Comprehensive Review

Rev Cardiovasc Med. 2025 Dec 18;26(12):45204. doi: 10.31083/RCM45204. eCollection 2025 Dec.ABSTRACTHypertension is a prominent cardiovascular risk factor, especially among patients with diabetes and obesity. Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) are a class of drugs originally develo

D Dhir Gala

A Comprehensive Review of the Management of Light-Chain (AL) and Transthyretin (ATTR) Cardiac Amyloidosis

Rev Cardiovasc Med. 2025 Dec 18;26(12):42609. doi: 10.31083/RCM42609. eCollection 2025 Dec.ABSTRACTCardiac amyloidosis, once considered a rare and untreatable disorder, is now increasingly recognized as a significant cause of heart failure, particularly in older adults. The two most clinically relev

A Ahmad Alkhatib

Contemporary Percutaneous Coronary Intervention in Diabetic Patients

Rev Cardiovasc Med. 2025 Dec 22;26(12):44861. doi: 10.31083/RCM44861. eCollection 2025 Dec.ABSTRACTCoronary artery disease is a leading cause of morbidity and mortality in patients with type 2 diabetes mellitus. Indeed, diabetic patients often present with silent or atypical symptoms and are more li

F Francesco Tartaglia

Takotsubo Cardiomyopathy: An Exploration of the Intersection Between Stress, Coronary Dysfunction, and Cardiac Outcomes

Rev Cardiovasc Med. 2025 Dec 23;26(12):45857. doi: 10.31083/RCM45857. eCollection 2025 Dec.ABSTRACTTakotsubo syndrome (TTS) is an acute, reversible form of left ventricular dysfunction, typically triggered by emotional or physical stress. The hallmark feature is reversible regional wall motion abnor

D Davide Rossi

Exploration of Spontaneous Coronary Artery Dissection: Pathophysiology, Diagnosis, Management, and Clinical Implications

Rev Cardiovasc Med. 2025 Dec 22;26(12):45172. doi: 10.31083/RCM45172. eCollection 2025 Dec.ABSTRACTEvidence is accumulating that shows spontaneous coronary artery dissection (SCAD) as a recognized cause of acute coronary syndrome (ACS), disproportionately affecting younger people and women. Moreover

A Aro Daniela Arockiam

Left Atrial Reservoir Strain in Cardiovascular and Systemic Disease: Advances and Clinical Applications From Physiology to Practice

Rev Cardiovasc Med. 2025 Dec 25;26(12):46198. doi: 10.31083/RCM46198. eCollection 2025 Dec.ABSTRACTTraditional parameters, such as left atrial size or volume, typically reflect chronic pressure and volume overload; however, these abnormalities only become evident at advanced stages, often missing ea

A Andrea Sonaglioni

Precision Medicine for Electrocardiogram Interpretation: Clinical Relevance, Challenges, and Advances

Rev Cardiovasc Med. 2025 Dec 24;26(12):47007. doi: 10.31083/RCM47007. eCollection 2025 Dec.ABSTRACTElectrocardiograms (ECGs) remain a foundational pillar of cardiovascular diagnostics, providing rapid, non-invasive diagnosis and being universally accessible to all clinicians. An ECG captures the ele

K Kamran Namjouyan

Safety and Efficacy of Novel Morphology Classification-Guided Mitral Valve Transcatheter Edge-to-Edge Repair for Patients With Commissural Degenerative Mitral Regurgitation: Design and Rationale of the TEER-CD Trial

Rev Cardiovasc Med. 2025 Dec 19;26(12):39373. doi: 10.31083/RCM39373. eCollection 2025 Dec.ABSTRACTBACKGROUND: Mitral commissural prolapse or flail, characterized by intricate and diverse anatomical features, poses a significant challenge in mitral transcatheter edge-to-edge repair (M-TEER). Previou

Y Yang Li

Beta-Blockers in Stable Coronary Artery Disease: A Systematic Review and Meta-Analysis of Observational Studies

Rev Cardiovasc Med. 2025 Dec 23;26(12):44520. doi: 10.31083/RCM44520. eCollection 2025 Dec.ABSTRACTBACKGROUND: The efficacy of beta-blockers in stable coronary artery disease (CAD) patients with preserved left ventricular function remains controversial. We aimed to evaluate the cardiovascular associ

J Jing-Xuan Liu

Accelerated Biological Aging, Genetic Susceptibility, and the Risk of Abdominal Aortic Aneurysm: A Prospective Cohort Study

Rev Cardiovasc Med. 2025 Dec 4;26(12):46778. doi: 10.31083/RCM46778. eCollection 2025 Dec.ABSTRACTBACKGROUND: Biological age (BA) more accurately reflects the true ageing status of the body compared with chronological age. While biological aging is associated with various cardiovascular diseases, th

Y Yiyang Tang

The Relationship Between the C-reactive Protein-Triglyceride Glucose Index and the Risk of Coronary Heart Disease Alongside the Severity of Coronary Artery Stenosis in Older Adults With Different Levels of Glucose Metabolism: A Real-World Retrospective Clinical Study

Rev Cardiovasc Med. 2025 Dec 16;26(12):45886. doi: 10.31083/RCM45886. eCollection 2025 Dec.ABSTRACTBACKGROUND: Coronary heart disease (CHD), one of the most severe cardiovascular conditions, poses a significant threat to the health and survival of older adults. Numerous studies have confirmed that d

Q Qinyu Sun

Endothelin as a Treatment Target in Cardiovascular Diseases: A Recent Step Forward

Rev Cardiovasc Med. 2025 Dec 22;26(12):45417. doi: 10.31083/RCM45417. eCollection 2025 Dec.ABSTRACTCardiovascular diseases (CVDs) are a leading cause of mortality, significantly influencing quality of life and causing a burden on the healthcare system. Current treatment strategies utilize modern the

A Aleksandra Cole

Utility of Cardiac Rehabilitation Following Surgical Treatment of Infective Endocarditis

Rev Cardiovasc Med. 2025 Dec 23;26(12):45789. doi: 10.31083/RCM45789. eCollection 2025 Dec.ABSTRACTInfective endocarditis (IE) is a life-threatening cardiac infection. The incidence of IE is increasing due to complex sociodemographic shifts, including increases in intravenous drug use (IVDU) attribu

S Sara M Telles-Langdon

Synthetic and Tissue-Engineered Vascular Grafts: Current Status, Emerging Technologies, and Clinical Prospects

Rev Cardiovasc Med. 2025 Dec 23;26(12):45083. doi: 10.31083/RCM45083. eCollection 2025 Dec.ABSTRACTCardiovascular diseases (CVDs) are the leading cause of morbidity and mortality worldwide, creating an urgent demand for small-diameter vascular substitutes with durable long-term patency. Large-calibe

K Kejian Gong

Novel Echocardiographic Index for Risk Stratification of Ventricular Arrhythmias and Mortality Based on Right Ventricular Function

J Arrhythm. 2026 Jan 8;42(1):e70244. doi: 10.1002/joa3.70244. eCollection 2026 Feb.ABSTRACTBACKGROUND: Right ventricular (RV) dysfunction is independently predictive of sudden cardiac death. This study aimed to compare the performance of different risk stratification methods for death and appropriat

T Toshinori Chiba

Association of Systemic Inflammation Indices With Mortality in Coronary Atherosclerosis Patients With and Without Standard Modifiable Risk Factors

Mediators Inflamm. 2026 Jan 10;2026:8830121. doi: 10.1155/mi/8830121. eCollection 2026.ABSTRACTBACKGROUND: Standard modifiable risk factors (SMuRFs) are important causative factors leading to coronary atherosclerosis. However, a significant number of individuals develop coronary atherosclerosis desp

W Weiren Yan

A scoping review of digital health applications for managing noncommunicable diseases in primary care post-pandemic: Lessons from the Western Pacific Region

Malays Fam Physician. 2025 Dec 2;20:77-100. doi: 10.51866/rv.919. eCollection 2025.ABSTRACTINTRODUCTION: The global rise of digital health is reshaping healthcare delivery and improving outcomes, especially for noncommunicable diseases (NCDs) post-pandemic. Guided by the World Health Organization (W

M Muhammad Solehuddin Ishak

Design and Framework of JROAD-DPC - A Japanese Nationwide Registry Linking Diagnosis Procedure Combination Data With Cardiovascular Quality Metrics

Circ Rep. 2025 Nov 12;8(1):180-189. doi: 10.1253/circrep.CR-25-0217. eCollection 2026 Jan 9.ABSTRACTBACKGROUND: Comprehensive monitoring of cardiovascular disease (CVD) is essential in rapidly aging societies such as Japan. The Japanese Circulation Society (JCS) launched the Japanese Registry Of All

T Tatsuhiro Shibata

Implementation and Challenges of Early-Phase Physiotherapy During Cardiovascular Intensive Care

Circ Rep. 2025 Dec 9;8(1):21-26. doi: 10.1253/circrep.CR-25-0252. eCollection 2026 Jan 9.ABSTRACTProgress in intensive care for cardiovascular disease, including catheter-based therapies and mechanical circulatory support, has improved patient survival. Conversely, the numbers of patients with sever

N Nobuaki Hamazaki

Imaging-guided stratification in giant cell arteritis: prognostic and therapeutic implications

Ther Adv Musculoskelet Dis. 2026 Jan 7;18:1759720X251414122. doi: 10.1177/1759720X251414122. eCollection 2026.ABSTRACTImaging has become a cornerstone in the clinical management of giant cell arteritis (GCA), with its role extending beyond diagnosis to include disease monitoring, risk stratification

J Juan Molina-Collada

Gas chromatography-mass spectrometry-based plasma metabolomics analysis in hypertensive patients with Yin deficiency and Yang hyperactivity syndrome

World J Exp Med. 2025 Sep 20;15(3):103154. doi: 10.5493/wjem.v15.i3.103154. eCollection 2025 Sep 20.ABSTRACTBACKGROUND: Hypertension is a significant global health concern and serves as a critical risk factor for cardiovascular diseases, stroke, and renal failure. Traditional Chinese Medicine (TCM)

D Dinala Jialiken

Comparative Effectiveness of Sodium-Glucose Cotransporter-2 (SGLT2) Inhibitors Versus Glucagon-Like Peptide-1 (GLP-1) Agonists on Cardiovascular and Renal Outcomes in Type 2 Diabetes: A Systematic Review and Network Meta-Analysis

Cureus. 2026 Jan 6;18(1):e100927. doi: 10.7759/cureus.100927. eCollection 2026 Jan.ABSTRACTSodium-glucose cotransporter-2 (SGLT2) inhibitors and glucagon-like peptide-1 (GLP-1) receptor agonists reduce cardiovascular and renal risks in type 2 diabetes mellitus (T2DM), but their relative efficacy rem

A Aymen A Alqurain