J Physiol Pharmacol. 2026 Feb;77(1):xxx. doi: 10.26402/jpp.2026.1.03. Epub 2026 Apr 2.ABSTRACTThis review focuses on analysing existing research to offer a comprehensive understanding of the complex role minerals play in the pathophysiology of ischaemia. By examining changes in mineral levels, we ai
Neurology. 2026 May 12;106(9):e214709. doi: 10.1212/WNL.0000000000214709. Epub 2026 Apr 3.ABSTRACTBACKGROUND AND OBJECTIVES: According to region-specific hospital-based studies, the location of ruptured intracranial aneurysm (RIA) influences the case fatality rate (CFR) of aneurysmal subarachnoid he
Curr Hypertens Rev. 2026 Mar 25. doi: 10.2174/0115734021428187260122072751. Online ahead of print.ABSTRACTHypertension poses a significant global health burden due to its prevalence and serves as a major risk factor for cardiovascular diseases (CVDs) such as stroke, heart failure, myocardial infarct
J Bras Nefrol. 2026 Jul-Sep;48(3):e20250318. doi: 10.1590/2175-8239-JBN-2025-0318en.ABSTRACTBACKGROUND: Sacubitril/valsartan is a recommended medication for managing heart failure (HF). However, its role in peritoneal dialysis (PD) patients remains uncertain. We conducted this systematic review and
Recent Adv Inflamm Allergy Drug Discov. 2026 Mar 26. doi: 10.2174/0127722708420100260210104129. Online ahead of print.ABSTRACTINTRODUCTION: Angiotensin II receptor blockers (ARBs) are a group of drugs widely used in the treatment of high blood pressure, cardiovascular and renal diseases, and diabete
Sci Adv. 2026 Apr 3;12(14):eaeb1134. doi: 10.1126/sciadv.aeb1134. Epub 2026 Apr 3.ABSTRACTNOTCH3 variants cause CADASIL (cerebral autosomal dominant arteriopathy and subcortical infarcts and leukoencephalopathy), the most common monogenetic form of small vessel disease (SVD) and vascular dementia (V
PLoS One. 2026 Apr 3;21(4):e0346145. doi: 10.1371/journal.pone.0346145. eCollection 2026.ABSTRACTBACKGROUND: Proton pump inhibitors are standard for preventing upper gastrointestinal (UGI) complications in patients receiving antithrombotic therapy, but their limitations highlight the need for altern
PLoS One. 2026 Apr 3;21(4):e0344682. doi: 10.1371/journal.pone.0344682. eCollection 2026.ABSTRACTBACKGROUND: Hypertension is a major risk factor associated with cardiovascular diseases and one of the leading causes of premature death. Metabolomics is a useful tool for studying in vivo metabolic prof
PLoS One. 2026 Apr 3;21(4):e0346141. doi: 10.1371/journal.pone.0346141. eCollection 2026.ABSTRACTHyperuricemia (HUA) is an independent risk factor for cardiovascular disease (CVD), and low serum vitamin D levels are associated with an increased risk of CVD. However, their combined effect in patients
PLoS Comput Biol. 2026 Apr 3;22(4):e1013740. doi: 10.1371/journal.pcbi.1013740. Online ahead of print.ABSTRACTEngineered heart tissues (EHTs) have shown promise in partially restoring ejection fraction after myocardial infarction (MI); however, their potential to introduce electrophysiological heter
PLoS One. 2026 Apr 3;21(4):e0346326. doi: 10.1371/journal.pone.0346326. eCollection 2026.ABSTRACTHypertension is one of the main causes of cardiovascular diseases worldwide, affecting over one billion people. Although aliskiren offers a valuable option for inhibiting the renin-angiotensin system, it
Am J Case Rep. 2026 Apr 3;27:e951333. doi: 10.12659/AJCR.951333.ABSTRACTBACKGROUND Acupuncture can pose a risk for both local and metastatic infections, particularly when performed under poor sterilization conditions. To date, a few cases of acupuncture-associated infective endocarditis (IE) have be
Medicine (Baltimore). 2026 Apr 3;105(14):e48270. doi: 10.1097/MD.0000000000048270.ABSTRACTThis study aimed to develop a prediction model based on nomograms and support vector machines (SVM) to assess frailty risk in ischemic stroke patients. Clinical information of ischemic stroke patients admitted
Medicine (Baltimore). 2026 Apr 3;105(14):e48218. doi: 10.1097/MD.0000000000048218.ABSTRACTCardiac arrest (CA) remains one of the leading causes of mortality in intensive care units. Most patients with CA receive vasoactive drugs; however, the relationship between cardiovascular responsiveness to the
Medicine (Baltimore). 2026 Apr 3;105(14):e48247. doi: 10.1097/MD.0000000000048247.ABSTRACTOur study aims to investigate the causal effects of life course adiposity on diabetic microvascular complications. Life course adiposity was considered as the exposure, including adult body mass index (BMI), ch
Medicine (Baltimore). 2026 Apr 3;105(14):e48194. doi: 10.1097/MD.0000000000048194.ABSTRACTThis study aimed to identify risk factors for fear of disease progression (FoP) among stroke survivors and propose management strategies. A cross-sectional study of 149 stroke patients (February 2022-March 2025
Medicine (Baltimore). 2026 Apr 3;105(14):e48220. doi: 10.1097/MD.0000000000048220.ABSTRACTAlthough numerous studies have investigated the associations between micronutrients and peripheral artery disease (PAD), most existing evidence is observational and limited by confounding and lack of causal inf
Medicine (Baltimore). 2026 Apr 3;105(14):e48241. doi: 10.1097/MD.0000000000048241.ABSTRACTAlthough estimated glomerular filtration rate (eGFR) is a key indicator of kidney function, its association with mortality in herpes simplex virus (HSV)-seropositive individuals remains unclear. We analyzed 17,
Medicine (Baltimore). 2026 Apr 3;105(14):e48159. doi: 10.1097/MD.0000000000048159.ABSTRACTINTRODUCTION: Myocardial bridge (MB) is a congenital coronary artery malformation, generally considered benign. However, we reported 2 cases of long and deep coronary MB in children and their surgical treatment
Medicine (Baltimore). 2026 Apr 3;105(14):e48169. doi: 10.1097/MD.0000000000048169.ABSTRACTMortality and hospitalization rates of heart failure (HF) increase with advancing age. However, the elderly are underrepresented in clinical trials; therefore, data on in-hospital outcomes and influencing facto
Medicine (Baltimore). 2026 Apr 3;105(14):e46522. doi: 10.1097/MD.0000000000046522.ABSTRACTCardiac amyloidosis (CA) frequently coexists with atrial fibrillation (AF), but the extent and impact of this relationship remain unclear. This study investigates the prevalence of AF in CA, compares clinical c
Medicine (Baltimore). 2026 Apr 3;105(14):e48193. doi: 10.1097/MD.0000000000048193.ABSTRACTBACKGROUND: Computed tomography angiography (CTA) is a vital preoperative diagnostic tool for chronic limb-threatening ischemia (CLTI). However, its high radiation dose and reliance on iodine contrast agents po
Medicine (Baltimore). 2026 Apr 3;105(14):e48210. doi: 10.1097/MD.0000000000048210.ABSTRACTValvular heart disease (VHD) is a common cardiovascular disorder with insidious early symptoms and can progress to heart failure or sudden death. Pharmacological options remain limited, and severe disease often
Medicine (Baltimore). 2026 Apr 3;105(14):e48219. doi: 10.1097/MD.0000000000048219.ABSTRACTRelative fat mass (RFM) is an anthropometric index calculated from height, waist circumference, and sex (RFM = 64 - [20 × height/ waist circumference] + [12 × sex], where sex = 1 for females and 0 for males), d
