J Med Internet Res. 2025 Dec 1;27:e82442. doi: 10.2196/82442.ABSTRACTBACKGROUND: Hemispatial neglect affects approximately 33% of patients after acute stroke and is linked to poor recovery. Auditory motion stimulation, particularly using spatial cues, can enhance spatial awareness and has shown prom
Biomedica. 2025 Nov 27;45(Sp. 2):41-55. doi: 10.7705/biomedica.8068.ABSTRACTINTRODUCTION: Wildfire activity is intensifying in Latin America due to climate and land-use changes, but the health impacts of wildfire-derived PM2.5 in urban areas remain poorly quantified and recognized.OBJECTIVE: To asse
Proc Natl Acad Sci U S A. 2025 Dec 9;122(49):e2512046122. doi: 10.1073/pnas.2512046122. Epub 2025 Dec 1.ABSTRACTTight junctions seal the paracellular space between epithelial cells, with their claudin (CLDN) composition dictating epithelial permeability properties. In kidney thick ascending limbs, c
PLoS One. 2025 Dec 1;20(12):e0337903. doi: 10.1371/journal.pone.0337903. eCollection 2025.ABSTRACTBACKGROUND: The atherogenic index of plasma (AIP) is a recognized marker of atherosclerosis and cardiovascular disease (CVD). However, the association between AIP and the risk of acute kidney injury (AK
J Vis Exp. 2025 Nov 11;(225). doi: 10.3791/68682.ABSTRACTThe paper aims to investigate the difference between the effect of enoxaparin alone and enoxaparin + lower limb circulation (LLC) in the prevention of deep vein thrombosis (DVT) after intertrochanteric fracture in older people and to provide a
Cardiology. 2025 Dec 1:1-16. doi: 10.1159/000549181. Online ahead of print.ABSTRACTINTRODUCTION: The lipid accumulation product (LAP) is a sex-specific index that reflects visceral adiposity and lipid imbalance. This study aimed to investigate the prospective association between LAP and cardiometabo
Horm Res Paediatr. 2025 Dec 1:1-14. doi: 10.1159/000549075. Online ahead of print.ABSTRACTBACKGROUND: Endocrine science remains underrepresented in European Union research programs despite the fundamental role of hormone health in human well-being. Analysis of the CORDIS database reveals a persisten
J Vis Exp. 2025 Nov 14;(225). doi: 10.3791/67181.ABSTRACTIschemia-reperfusion (IR) injuries are associated with several pathologies, including testicular injury. Earlier animal models of testicular IR, which involves twisting the spermatic cord to achieve ischemia, are fraught with many technical di
PLoS One. 2025 Dec 1;20(12):e0337841. doi: 10.1371/journal.pone.0337841. eCollection 2025.ABSTRACTBACKGROUND: Faster time to reperfusion can be achieved by minimizing various patient and system-level delays that contribute to total ischemic time. Procedural delays within the catheterization laborato
J Cardiovasc Nurs. 2026 Jan-Feb 01;41(1):59-64. doi: 10.1097/JCN.0000000000001196. Epub 2025 Nov 25.ABSTRACTBACKGROUND: Home monitoring programs (HMPs) have been implemented for high-risk postoperative patients with congenital heart diseases.OBJECTIVE: We recently extended the indications for HMPs t
PLoS One. 2025 Dec 1;20(12):e0337059. doi: 10.1371/journal.pone.0337059. eCollection 2025.ABSTRACTEpidemiological data on gastroesophageal reflux disease (GERD) reveal variations in prevalence rates and risk factors, which are still to be elucidated in the South African setting. Population-specific
J Vis Exp. 2025 Nov 14;(225). doi: 10.3791/69418.ABSTRACTStroke is a leading cause of death and disability across the globe. During ischemic stroke, an obstructed cerebral blood vessel causes focal metabolic failure, neuronal membrane potential breakdown, and dramatic neuronal Ca2+ influx as part of
Am J Case Rep. 2025 Dec 1;26:e948995. doi: 10.12659/AJCR.948995.ABSTRACTBACKGROUND Transcatheter aortic valve implantation (TAVI) is a less invasive option for severe aortic stenosis in patients unfit for surgery. Its use has substantially expanded due to its safety profile and clinical efficacy in
J Vis Exp. 2025 Nov 14;(225). doi: 10.3791/69427.ABSTRACTEpicardial adipose tissue (EAT), an active endocrine and paracrine organ, contributes to cardiovascular pathogenesis. While cardiac magnetic resonance (CMR) is the reference standard for quantifying EAT volume (EATV), its clinical utility is l
J Vis Exp. 2025 Nov 14;(225). doi: 10.3791/69409.ABSTRACTThe continuous infusion of Angiotensin II (Ang II) via osmotic pumps is a widely utilized approach for establishing animal models of hypertensive myocardial fibrosis. Nevertheless, this technique exhibits certain limitations in current reports
No abstractAm J Hypertens. 2025 Oct 11:hpaf187. doi: 10.1093/ajh/hpaf187. Online ahead of print.NO ABSTRACTPMID:41325266 | DOI:10.1093/ajh/hpaf187
J Vis Exp. 2025 Nov 14;(225). doi: 10.3791/68998.ABSTRACTPrimary amebic meningitis is a rare, acute, fatal central nervous system disease caused by Naegleria fowleri infection. In the past, the resulting damage to the central nervous system has received more attention, whereas the impact on the hear
J Physiol Investig. 2025 Nov 1;68(6):358-371. doi: 10.4103/ejpi.EJPI-D-25-00044. Epub 2025 Nov 25.ABSTRACTC-C chemokine receptor 5 (CCR5) regulates immune responses, inflammation, and tissue remodeling, but its baseline role in cardiac and metabolic homeostasis remains unclear. Using CCR5 knockout (
Cardiovasc Res. 2025 Dec 1:cvaf265. doi: 10.1093/cvr/cvaf265. Online ahead of print.ABSTRACTAIMS: The adult mammalian heart possesses severely limited regenerative capacity. Cardiomyocyte loss during cardiac injury, coupled with this restricted regenerative potential, represents a fundamental cause
Cardiovasc Res. 2025 Oct 27:cvaf208. doi: 10.1093/cvr/cvaf208. Online ahead of print.ABSTRACTAIMS: Heart failure with preserved ejection fraction (HFpEF) is one of the most common forms of heart failure with no effective treatment. While chronic systemic inflammation, triggered by comorbidities, is
Crit Pathw Cardiol. 2025 Dec 1;24(4):e0405. doi: 10.1097/HPC.0000000000000405. Epub 2025 Sep 29.ABSTRACTBACKGROUND: Heart failure (HF) is a leading cause of hospitalization in the United States. The goal of this study was to evaluate contemporary population-level trends and demographic disparities i
Gut Microbes. 2025 Dec 31;17(1):2592431. doi: 10.1080/19490976.2025.2592431. Epub 2025 Dec 1.ABSTRACTExcessive intake of added sugars is a global public health concern, given its established links with cardiometabolic disease and other chronic conditions. Emerging evidence suggests that the gut micr
Am J Physiol Heart Circ Physiol. 2025 Dec 1. doi: 10.1152/ajpheart.00835.2025. Online ahead of print.ABSTRACTSmall extracellular vesicles (EVs) have become essential mediators of intercellular and inter-organ communication in vivo, with significant therapeutic potential and prognostic value in cardi
Eur J Ophthalmol. 2025 Dec 1:11206721251403039. doi: 10.1177/11206721251403039. Online ahead of print.ABSTRACTPurposeTo investigate the association between PREVENT, a cardiovascular disease (CVD) risk estimation model, and quantitative parameters derived from choroidal vascular imaging.MethodsWe con
