Eur Heart J. 2026 Jun 16:ehag403. doi: 10.1093/eurheartj/ehag403. Online ahead of print.ABSTRACTBACKGROUND AND AIMS: The role of genetic testing as part of universal screening programmes for familial hypercholesterolaemia (FH) in children is not well defined. Here, a two-step approach to identify ch
No abstractEur Heart J. 2026 Jun 16:ehag470. doi: 10.1093/eurheartj/ehag470. Online ahead of print.NO ABSTRACTPMID:42301735 | DOI:10.1093/eurheartj/ehag470
Recenti Prog Med. 2026 Jun;117(6):279-287. doi: 10.1701/4716.47322.ABSTRACTINTRODUCTION: Heart Failure (HF) represents a critical challenge for the National Health Service (SSN) in terms of mortality and costs, often fueled by fragmented management between hospital and community care. The objective
Geroscience. 2026 Jun 16. doi: 10.1007/s11357-026-02356-y. Online ahead of print.ABSTRACTDual declines in cognitive status and physical performance increase dementia risk but shared biological mechanisms between processes remain unclear. We investigated plasma proteomic signatures underlying dual de
Geroscience. 2026 Jun 16. doi: 10.1007/s11357-026-02339-z. Online ahead of print.ABSTRACTThe growing burden of aging-related disease and functional decline across Europe underscores the urgent need to optimize aging trajectories rather than simply extend lifespan. Achieving this goal requires identi
Transl Stroke Res. 2026 Jun 16;17(4):68. doi: 10.1007/s12975-026-01459-0.ABSTRACTHome-based rehabilitation after stroke is increasingly important, as pressure on hospital services rise and recovery occurs mostly at home. Enriching the home (Environmental Enrichment, EE) represents a potential strate
J Interv Card Electrophysiol. 2026 Jun 16. doi: 10.1007/s10840-026-02369-9. Online ahead of print.ABSTRACTThis narrative, hypothesis-generating review examines whether patent foramen ovale (PFO), usually discussed through stroke prevention, may be linked to atrial cardiomyopathy (AtCM) in selected l
Metab Brain Dis. 2026 Jun 16;41(1):135. doi: 10.1007/s11011-026-01901-0.ABSTRACTIschemic stroke is a major cause of mortality globally, but single-target therapies often fail due to the complex "ischemic cascade". This study investigated the neuroprotective effects and multitarget mechanisms of Curc
Neurol Ther. 2026 Jun 16. doi: 10.1007/s40120-026-00973-5. Online ahead of print.ABSTRACTINTRODUCTION: Metabolic comorbidities, including central adiposity, dyslipidemia, insulin resistance, and hypertension, are common in individuals with schizophrenia and contribute to an increased risk of cardiov
Eur J Pediatr. 2026 Jun 16;185(7):506. doi: 10.1007/s00431-026-07164-2.ABSTRACTThe purpose of this study was to investigate the association between SREBP gene polymorphisms and ambulatory blood pressure phenotypes. In the present study, 514 college students from a university in China were recruited.
Surg Endosc. 2026 Apr 20. doi: 10.1007/s00464-026-12678-9. Online ahead of print.ABSTRACTINTRODUCTION: Although minimally invasive (MIS) liver resections are associated with improved outcomes, uptake remains slow.METHODS: Using data from the Healthcare Cost and Utilization Project (HCUP) National In
Eur J Trauma Emerg Surg. 2026 Jun 16;52(1):197. doi: 10.1007/s00068-026-03233-1.ABSTRACTBACKGROUND: Prehospital Traumatic cardiac arrest has a high fatality rate despite advances in trauma systems and resuscitation strategies. Mechanical chest compression devices have been increasingly adopted to op
Neurochem Res. 2026 Jun 16;51(4):197. doi: 10.1007/s11064-026-04815-6.ABSTRACTElectroacupuncture (EA) has been documented to exert therapeutic benefits in vascular dementia (VD). This study seeks to elucidate the therapeutic efficacy and underlying molecular mechanisms of EA in VD. A VD model was in
CEN Case Rep. 2026 Jun 16;15(4):99. doi: 10.1007/s13730-026-01143-0.ABSTRACTA man in his early 60 s developed persistent hyponatremia following lumbar spine surgery complicated by traumatic brain injury with subarachnoid hemorrhage. Initial evaluation demonstrated hypotonic hyponatremia with inappro
Curr Opin Cardiol. 2026 Jun 16. doi: 10.1097/HCO.0000000000001322. Online ahead of print.ABSTRACTPURPOSE OF REVIEW: Conventional coronary artery bypass grafting (CABG) is most commonly performed via median sternotomy, an approach that can be associated with postoperative pain, sternal wound complica
Eur J Prev Cardiol. 2026 Jun 16:zwag304. doi: 10.1093/eurjpc/zwag304. Online ahead of print.ABSTRACTBACKGROUND: In FOURIER, the PCSK9 inhibitor evolocumab (Evo) significantly reduced the rate of major adverse cardiovascular events and coronary revascularization.AIMS: To investigate the effect of evo
Eur J Prev Cardiol. 2026 Jun 16:zwag212. doi: 10.1093/eurjpc/zwag212. Online ahead of print.ABSTRACTAIMS: Social isolation (SI) is associated with a higher risk of cardiovascular disease (CVD). One mechanism linking SI and CVD is accelerated biological ageing, which can be assessed using artificial
JACC Case Rep. 2026 Jun 16:108821. doi: 10.1016/j.jaccas.2026.108821. Online ahead of print.ABSTRACTBACKGROUND: Severe hypertriglyceridemia can cause significant metabolic complications and spurious laboratory results, complicating clinical decision-making. Chylomicronemia syndromes, particularly mu
JACC Case Rep. 2026 Jun 3:108748. doi: 10.1016/j.jaccas.2026.108748. Online ahead of print.ABSTRACTBACKGROUND: Sinus venosus atrial septal defects with partial anomalous pulmonary venous return (PAPVR) are rare congenital abnormalities.CASE SUMMARY: A 26-year-old competitive swimmer with Klinefelter
Diabetes Care. 2026 Jun 16:dc252040. doi: 10.2337/dc25-2040. Online ahead of print.ABSTRACTOBJECTIVE: To examine national trends in out-of-pocket (OOP) costs for glucose-lowering medications among U.S. adults with diabetes from 2000 to 2022.RESEARCH DESIGN AND METHODS: We analyzed Medical Expenditur
Anatol J Cardiol. 2026 Jun 16. doi: 10.14744/AnatolJCardiol.2026.6593. Online ahead of print.ABSTRACTHealthy soils and clean water are essential for human survival, yet, both are increasingly compromised by chemical and plastic pollution. This preventable crisis causes an estimated 9 million prematu
Diabetes. 2026 Jun 16:db250859. doi: 10.2337/db25-0859. Online ahead of print.ABSTRACTRibosomal S6 kinase 4 (Rsk4) is predominantly expressed in hypothalamic neurons. Rsk4 is negligible for maintaining energy homeostasis in mice. Loss of Rsk4 promotes diet-induced obesity and related metabolic disor
J Mater Chem B. 2026 Jun 8. doi: 10.1039/d6tb00661b. Online ahead of print.ABSTRACTConventional optical imaging is constrained by photon absorption and multiple scattering in biological tissues. Extending excitation and emission into the second near-infrared window (NIR-II, 1000-1700 nm) markedly su
Background Cardiac gallium 68-labeled fibroblast activation protein inhibitor (FAPI)-4 (^(68)Ga-FAPI-4) PET/MRI allows simultaneous assessment of cardiac tissue characteristics, function, and molecular remodeling in myocardial diseases. An integrated workflow for nonischemic dilated cardiomyopathy (
