Transthoracic Echocardiography-Guided Implantation of Aveir VR Leadless Pacemaker Without Fluoroscopy

Pacing Clin Electrophysiol. 2026 Feb 27. doi: 10.1111/pace.70176. Online ahead of print.ABSTRACTBACKGROUND: Leadless pacemaker implantation traditionally relies on fluoroscopy and contrast-guided techniques. However, in patients with advanced chronic kidney disease, the use of contrast carries a ris

H Haojie Zhu

Survival and Risk Profile of Patients With Significant Tricuspid Regurgitation by Etiology

J Am Heart Assoc. 2026 Feb 27:e044323. doi: 10.1161/JAHA.125.044323. Online ahead of print.ABSTRACTBACKGROUND: Tricuspid regurgitation (TR) is a common valvular disorder that can affect patients' quality of life and survival. The impact of TR etiology on overall survival and the associated risk fact

M Mohamad S Alabdaljabar

Cardio-renal-metabolic syndrome: A concept in question, a clinical impact beyond doubt

No abstractDiabet Med. 2026 Feb 27:e70282. doi: 10.1111/dme.70282. Online ahead of print.NO ABSTRACTPMID:41757422 | DOI:10.1111/dme.70282

T Theocharis Koufakis

Low-Dose Rivaroxaban Plus Aspirin in Patients With PAD Undergoing Lower Extremity Revascularization With and Without History of Prior Limb Revascularization: Insight From the VOYAGER-PAD Trial

Circ Cardiovasc Interv. 2026 Feb 27:e015229. doi: 10.1161/CIRCINTERVENTIONS.125.015229. Online ahead of print.ABSTRACTBACKGROUND: Patients with peripheral artery disease (PAD) undergoing lower extremity revascularization (LER) are at high risk of major adverse limb events (MALE) and major adverse ca

M Mario Enrico Canonico

Association Between 24-Hour Systolic Blood Pressure Time in Target Range and Mortality

Hypertension. 2026 Feb 27. doi: 10.1161/HYPERTENSIONAHA.125.26112. Online ahead of print.ABSTRACTBACKGROUND: Time in target range (TTR) reflects the proportion of time blood pressure (BP) remains within a defined range, integrating BP variability and control. We examined associations of systolic BP

L Lucas Lauder

Mesenchymal stem cell-conditioned media alleviates diabetic cardiomyopathy by modulating glycemic control, oxidative stress-induced injury and inflammation regulation

J Diabetes Metab Disord. 2026 Feb 24;25(1):81. doi: 10.1007/s40200-026-01908-5. eCollection 2026 Jun.ABSTRACTA major consequence of diabetes mellitus (DM) is a diabetic cardiomyopathy (DC). It is a clinical confusion that is identified when individuals with DM develop ventricular dysfunction without

A Abeer M Abd El-Hameed

Association of inflammatory bowel disease with cardiovascular disease, and the mediating role of inflammation: a matched-cohort study

Therap Adv Gastroenterol. 2026 Feb 24;19:17562848261424145. doi: 10.1177/17562848261424145. eCollection 2026.ABSTRACTBACKGROUND: The elevated risk of cardiovascular disease (CVD) in inflammatory bowel disease (IBD) has been increasingly recognized. Although inflammation is implicated in both IBD and

J Jiawei Geng

Genetic polymorphisms of the CDC27 gene are associated with susceptibility and outcomes of non-syndromic congenital heart disease: a bi-ethnic case-control study in Chinese populations

Front Genet. 2026 Feb 12;17:1701812. doi: 10.3389/fgene.2026.1701812. eCollection 2026.ABSTRACTBACKGROUND: Cell division cycle 27 (CDC27) gene expression is closely associated with the cell cycle and has been implicated in the pathogenesis of congenital heart disease (CHD) in animal models. This stu

T Teng Yuan

All three coronary arteries and a separate conus branch arising from the right sinus of Valsalva in an octogenarian with an acute myocardial infarction: a case report

Eur Heart J Case Rep. 2026 Feb 6;10(2):ytag094. doi: 10.1093/ehjcr/ytag094. eCollection 2026 Feb.ABSTRACTBACKGROUND: Coronary artery anomalies are encountered in less than 1% of the population and are usually found incidentally. Some vessel courses are linked to myocardial ischaemia and sudden cardi

M Mihajlo Kovacic

Cardiac health assessment across scenarios and devices using a multimodal foundation model pretrained on data from 1.7 million individuals

Nat Mach Intell. 2026;8(2):220-233. doi: 10.1038/s42256-026-01180-5. Epub 2026 Feb 24.ABSTRACTCardiovascular diseases remain a major contributor to the global burden of healthcare, highlighting the importance of accurate and scalable methods for cardiac monitoring. Cardiac biosignals, most notably e

X Xiao Gu

Obesity and oxidative stress: potential mechanisms in endometrial disorders

Front Endocrinol (Lausanne). 2026 Feb 11;17:1709556. doi: 10.3389/fendo.2026.1709556. eCollection 2026.ABSTRACTObesity is a systemic metabolic disorder that is inducing factor for other diseases such as diabetes mellitus, cardiovascular diseases, malignancies, hepatic dysfunction, renal dysfunction

Y Yiwei Wang

Cardiovascular mortality associated with testosterone therapy in cisgender women and transgender men: a systematic review

Front Endocrinol (Lausanne). 2026 Feb 11;17:1789504. doi: 10.3389/fendo.2026.1789504. eCollection 2026.ABSTRACTBACKGROUND: Testosterone therapy is increasingly prescribed in cisgender women for sexual and metabolic indications and constitutes the cornerstone of gender-affirming hormone therapy in tr

D Diogo Pinto da Costa Viana

Comparative effectiveness of pemafibrate versus bezafibrate on hepatic and vascular endothelial function in patients with coronary artery disease and metabolic dysfunction-associated steatotic liver disease

Front Endocrinol (Lausanne). 2026 Feb 11;17:1750308. doi: 10.3389/fendo.2026.1750308. eCollection 2026.ABSTRACTBACKGROUND: Peroxisome proliferator-activated receptor (PPAR) agonists are promising therapeutic agents for metabolic dysfunction-associated steatotic liver disease (MASLD), which increases

A Akihiro Nakamura

Genetic Prediction of Circulating Lipoprotein(a) Levels in Diverse Populations

medRxiv [Preprint]. 2026 Feb 22:2026.02.20.26346738. doi: 10.64898/2026.02.20.26346738.ABSTRACTBACKGROUND: Circulating lipoprotein(a) [Lp(a)] levels are highly heritable and linked to atherosclerotic cardiovascular disease, yet clinical measurement rates remain low (<1%) in the United States. The hi

M Michael G Levin

Biomarkers for Atherosclerotic Cardiovascular Events in Rheumatoid Arthritis: Towards Validation of a Biomarker-Enhanced Risk Model

medRxiv [Preprint]. 2026 Feb 20:2026.02.18.26346592. doi: 10.64898/2026.02.18.26346592.ABSTRACTBACKGROUND: Cardiovascular (CV) disease risk is increased in rheumatoid arthritis (RA) and is the leading cause of mortality. Improved CV risk stratification tools in RA could enhance use of preventative c

D Daniel H Solomon

Secondary Prevention of Cardiovascular Events in Patients with Overweight/Obesity in Routine Clinical Practice

medRxiv [Preprint]. 2026 Feb 20:2026.02.18.26346594. doi: 10.64898/2026.02.18.26346594.ABSTRACTBACKGROUND AND AIMS: The glucagon-like peptide-1 receptor agonist (GLP-1 RA) semaglutide has demonstrated efficacy for the secondary prevention of cardiovascular disease among patients with overweight/obes

W Wenxin Guo

A Case Report of Statin-induced Myopathy, Rhabdomyolysis and Liver Injury (SILI): A Rare but Potentially Life-threatening Adverse Effect

Euroasian J Hepatogastroenterol. 2025 Jul-Dec;15(2):204-207. doi: 10.5005/jp-journals-10018-1488. Epub 2026 Jan 16.ABSTRACTAIM AND BACKGROUND: Statins are commonly used in patients with hyperlipidemia and with pre-existing coronary artery disease for primary and secondary cardiovascular risk reducti

K Kiran Kuraning

Wildfire emitted particulate matter induces ovarian hyperandrogenism through aryl hydrocarbon receptor activation

bioRxiv [Preprint]. 2026 Feb 19:2026.02.19.701615. doi: 10.64898/2026.02.19.701615.ABSTRACTWildfires have become more frequent and intense worldwide. Wildfire emitted particulate matter (WFPM) can be more toxic than urban background PM due to its greater content of nanoscale size (WFPM 0.1 ) and pre

K Kuhelika Mali

Insulin resistance modifies longitudinal multi-omics responses to habitual diet

bioRxiv [Preprint]. 2026 Feb 18:2026.02.17.706440. doi: 10.64898/2026.02.17.706440.ABSTRACTHow habitual diet influences the gut microbiome and plasma metabolome across insulin resistance states remains unclear. We conducted year-long multi-omics profiling of 71 deeply phenotyped adults, integrating

H Heyjun Park

EchoVisuALL: From Echocardiography to Gene Discovery

bioRxiv [Preprint]. 2026 Feb 19:2026.02.18.706519. doi: 10.64898/2026.02.18.706519.ABSTRACTCardiovascular diseases are a major global health burden, demanding phenotyping frame-works that can match the scale and complexity of contemporary mouse genetics. Here, we introduce EchoVisuALL, an AI-enabled

I Isabella Galter

Regulation of the Balance between Concentric and Eccentric Cardiac Hypertrophy by a CDC14A-KMT5A Signaling Pathway

bioRxiv [Preprint]. 2026 Feb 17:2026.02.16.706249. doi: 10.64898/2026.02.16.706249.ABSTRACTBACKGROUND: Depending upon the type of pathological stress, the heart undergoes concentric or eccentric remodeling. This structural change is associated with diastolic and/or systolic ventricular dysfunction r

X Xueyi Li

Negative [99mTc]Tc -DPD Scintigraphy, Presence of Monoclonal Protein and Biopsy Suggestive of AL Amyloidosis in a Patient With Homozygous p.Ala101Val Transthyretin Gene Variant

Clin Case Rep. 2026 Feb 24;14(3):e71928. doi: 10.1002/ccr3.71928. eCollection 2026 Mar.ABSTRACTAmyloidosis is a rare disease associated with the deposition of misfolded proteins that damage multiple organs, leading to a wide range of symptoms. The most frequently implicated proteins in amyloidosis i

P Paulina Kryszpin

In silico Analysis of CHD4 Mutations Reveals Domain-Specific Impacts on Cardiovascular Disorders Among Patients With Rare Diseases

Hum Mutat. 2026 Feb 25;2026:3575977. doi: 10.1155/humu/3575977. eCollection 2026.ABSTRACTChromodomain-helicase-DNA-binding protein 4 (CHD4) is a critical ATP-dependent chromatin remodeler that plays fundamental roles in transcriptional repression, DNA damage repair, and lineage specification, making

A Apolonia Novillo

Energy potential, health benefits, antinutrient reduction methods, and nutritional properties of Indian millets: a review

Front Nutr. 2026 Feb 11;13:1676670. doi: 10.3389/fnut.2026.1676670. eCollection 2026.ABSTRACTMillet production has significantly increased to fulfill the nutritional needs of the increased population across the globe. Around the world, millions of people suffer from shortages of food and hunger. In

N N R Gatkal