From global guidelines for cardio-kidney-metabolic diseases management to national implementation: perspectives from the guideline workshop taskforce

Cardiovasc Diabetol. 2026 Feb 23;25(1):66. doi: 10.1186/s12933-026-03098-z.ABSTRACTInternational guidelines define standards of care for type 2 diabetes (T2D), obesity, cardiovascular disease (CVD), metabolic dysfunction-associated steatotic liver disease (MASLD) and chronic kidney disease (CKD). Ye

C Christoph Wanner

The cholesterol, high-density lipoprotein, and glucose (CHG) index as a novel metabolic marker for predicting adverse outcomes in myocardial infarction survivors: insights from two large prospective cohorts

Cardiovasc Diabetol. 2026 Feb 24. doi: 10.1186/s12933-026-03104-4. Online ahead of print.ABSTRACTBACKGROUND: Post-myocardial infarction (MI) patients remain at high risk of mortality and recurrent cardiovascular events. Metabolic disorders in patients after MI are closely related to high residual ca

Y Yanjun Song

The combined effects of cardiometabolic index and high sensitivity C-reactive protein on cardiometabolic multimorbidity risk: a prospective analysis based on CHARLS

No abstractLipids Health Dis. 2026 Feb 23. doi: 10.1186/s12944-026-02904-7. Online ahead of print.NO ABSTRACTPMID:41731484 | DOI:10.1186/s12944-026-02904-7

H Hao Hua

Electronic cigarettes and cardiovascular outcomes: a systematic review and meta-analysis of Major Adverse Cardiovascular Events (MACE)

No abstractBMC Public Health. 2026 Feb 23;26(1):704. doi: 10.1186/s12889-026-26302-x.NO ABSTRACTPMID:41731465 | DOI:10.1186/s12889-026-26302-x

S Suraa N Al-Rubaye

Connection of smoking with risks of dyslipidemia, diabetes, and hypertension among adults in Northeast China: a cross-sectional study

BMC Public Health. 2026 Feb 24. doi: 10.1186/s12889-026-26700-1. Online ahead of print.ABSTRACTBACKGROUND: The high smoking prevalence and growing burden of chronic metabolic diseases have been threatening public health in Northeast China. This study aimed to investigate the association of smoking/q

Q Qian Zhao

Association of allostatic load index with cognitive impairment in high-risk stroke populations

BMC Geriatr. 2026 Feb 23. doi: 10.1186/s12877-026-07154-x. Online ahead of print.ABSTRACTBACKGROUND: Chronic psychosocial stress induces cumulative physiological dysregulation that accelerates biological aging and contributes to the development of cerebrovascular and neurocognitive disorders, includ

F Fengjuan Yan

Effect of Hormone Replacement Therapy on Liver and Cardiometabolic Outcomes in Peri-Menopausal MASLD

Liver Int. 2026 Apr;46(4):e70562. doi: 10.1111/liv.70562.ABSTRACTBACKGROUND: Metabolic dysfunction-associated steatotic liver disease (MASLD) is the most common chronic liver disease globally. Menopause is associated with increased hepatic fat deposition and thus metabolic dysfunction, contributing

A Alex E Henney

Plasma Exchange in ANCA-Associated Vasculitis With Kidney Involvement: Differential Outcomes by Kidney Function in a Colombian Cohort

J Clin Apher. 2026 Feb;41(1):e70099. doi: 10.1002/jca.70099.ABSTRACTANCA-associated vasculitis (AAV) frequently involves the kidneys and may progress to end-stage kidney disease (ESKD). The benefit of plasma exchange (PLEX) in this setting remains uncertain. We conducted a retrospective cohort study

C Clara Escorcia-García

Previous resistance exercise training mitigates progression of right ventricle dysfunction and remodeling in male rats with pulmonary arterial hypertension

Physiol Rep. 2026 Feb;14(4):e70786. doi: 10.14814/phy2.70786.ABSTRACTThis study investigated whether previous resistance exercise training (RT) affects the progression of right ventricular dysfunction and remodeling in rats with severe pulmonary artery hypertension (PAH). Male Wistar rats were submi

A Alexandre Martins Oliveira Portes

Iatrogenic Medication Errors Among Older Adults Reported to a Poison Center Network

Acad Emerg Med. 2026 Feb;33(2):e70248. doi: 10.1111/acem.70248.ABSTRACTBACKGROUND: Iatrogenic medication errors are a preventable source of harm in older adults. Yet their prevalence, types, and outcomes remain poorly characterized. This study aims to describe healthcare-associated iatrogenic medica

H Hayley T Gartner

Heart Failure in Kidney Transplant Recipients: Narrative Review of Risk Factors, Therapy, and Current Gaps in Management

Cardiol Ther. 2026 Feb 23. doi: 10.1007/s40119-026-00446-8. Online ahead of print.ABSTRACTAmong kidney transplant recipients (KTR), cardiovascular disease remains the leading cause of mortality, with heart failure (HF) being especially common in this population. Risk factors for HF in KTR can be cat

A Anukul Ghimire

Treatment preferences for comorbid obesity and obstructive sleep apnea (PRO-CON OSA) survey: Patient and provider preferences for CPAP and/or tirzepatide

No abstractJ Clin Sleep Med. 2026 Feb 23;22(1):35. doi: 10.1007/s44470-025-00024-0.NO ABSTRACTPMID:41731227 | DOI:10.1007/s44470-025-00024-0

C Christopher N Schmickl

Multifaceted roles for persulfide species in redox chemical biology

Nat Chem Biol. 2026 Feb 23. doi: 10.1038/s41589-026-02142-z. Online ahead of print.ABSTRACTReactive sulfur species (RSS) are increasingly recognized as important bioactive agents across phyla. Application of newly developed chemical tools, detection methods and multi-omics techniques has uncovered n

P Péter Nagy

Preoperative echocardiographic predictors of mitral valve repair failure in children

Eur J Pediatr. 2026 Feb 24;185(3):149. doi: 10.1007/s00431-026-06800-1.ABSTRACTThe objective of this study is to identify preoperative echocardiographic predictors of mitral valve (MV) repair failure in pediatric patients. Pediatric patients with mitral regurgitation (MR) grade ≥ 2 who received MV r

Y Yue Gao

Clinical features of osteoporosis in patients with type 1 and type 2 diabetes in Türkiye: A nationwide study

Arch Osteoporos. 2026 Feb 24;21(1):41. doi: 10.1007/s11657-026-01677-x.ABSTRACTThis nationwide study assessed clinical features of osteoporosis in Turkish adults with diabetes. Osteoporosis prevalence was 9.36% in type 1 diabetes and 19.13% in type 2 diabetes, with higher rates in women and older in

D Dilek Gogas Yavuz

In response to lean body mass index and hypertension risk in men: a nationwide epidemiological cohort study

No abstractHypertens Res. 2026 Feb 24. doi: 10.1038/s41440-026-02591-y. Online ahead of print.NO ABSTRACTPMID:41731070 | DOI:10.1038/s41440-026-02591-y

T Tatsuhiko Azegami

Targeting immunometabolic pathways with AZD1656 alleviates inflammation and metabolic dysfunction in type 2 diabetic cardiomyopathy

Nat Cardiovasc Res. 2026 Feb;5(2):138-154. doi: 10.1038/s44161-025-00769-0. Epub 2026 Feb 23.ABSTRACTType 2 diabetes (T2D) precipitates diabetic cardiomyopathy (dbCM), a condition characterized by chronic inflammation, metabolic dysregulation and impaired cardiac performance. Here we show that the g

S Stephanie Anderson

A reduced TBX5-dependent gene regulatory network links atrial fibrillation and heart failure

Nat Cardiovasc Res. 2026 Feb;5(2):96-117. doi: 10.1038/s44161-025-00775-2. Epub 2026 Feb 23.ABSTRACTAtrial fibrillation (AF) and heart failure (HF) frequently coexist and worsen one another's outcomes. To investigate shared molecular mechanisms, we compared atrial gene regulatory networks (GRNs) in

S Sonja Lazarevic

From Thymic Hypoplasia to Immune Reconstitution: An Immunological Review of DiGeorge Syndrome

Scand J Immunol. 2026 Mar;103(3):e70103. doi: 10.1111/sji.70103.ABSTRACTDiGeorge syndrome (DGS), also known as 22q11.2 deletion syndrome, is the most prevalent chromosomal microdeletion syndrome. It presents with a heterogeneous phenotype and diverse clinical manifestations, which may include, but a

A Alejandro Tarango-García

Deep learning meets clinical practice: A You Only Look Once-based framework for accurate and real-time detection of carotid vulnerable plaques

J Int Med Res. 2026 Feb;54(2):3000605261420504. doi: 10.1177/03000605261420504. Epub 2026 Feb 23.ABSTRACTObjectiveEarly and accurate detection of carotid vulnerable plaques is essential for preventing ischemic stroke. This study developed an automated deep learning framework using ultrasound images

H Hongzhen Zhang

Safety of Custodiol for Myocardial Protection in Minimally Invasive Mitral Valve Repair: A Japanese Single-Center Retrospective Comparison with Blood Cardioplegia in Conventional Sternotomy Repair

Ann Thorac Cardiovasc Surg. 2026;32(1). doi: 10.5761/atcs.oa.25-00208.ABSTRACTPURPOSE: Research regarding Custodiol's safety in minimally invasive mitral valve repair remains limited in Asian populations. We compared Custodiol in minimally invasive mitral valve repair to repetitive cold blood cardio

H Hiroaki Aizawa

Orbital MRI for diagnosing giant cell arteritis in cases of anterior ischaemic optic neuropathy

RMD Open. 2026 Feb 23;12(1):e006370. doi: 10.1136/rmdopen-2025-006370.ABSTRACTOBJECTIVES: Acute anterior ischaemic optic neuropathy (AION) is a feared ischaemic complication of giant cell arteritis (GCA). However, distinguishing arteritic AION (A-AION) from its non-arteritic counterpart (NA-AION), w

G Guillaume Brenac

Impact of invasive coronary function testing on management of ANOCA patients and secondary care resource utilisation: insights from a multicentre retrospective study in the UK

Open Heart. 2026 Feb 23;13(1):e003910. doi: 10.1136/openhrt-2025-003910.ABSTRACTBACKGROUND: Invasive coronary function testing (CFT) is indicated in patients with refractory angina with non-obstructed coronary arteries (ANOCA). Despite this, questions remain regarding patient selection for testing,

J Joanna Abramik

Physical activity advice from general practitioners in Germany: findings from a cross-sectional population survey of individuals with chronic ischaemic heart disease (OptiCor study)

BMJ Open. 2026 Feb 23;16(2):e101017. doi: 10.1136/bmjopen-2025-101017.ABSTRACTOBJECTIVES: The current German treatment guideline for chronic ischaemic heart disease (IHD) recommends that general practitioners (GPs) deliver brief advice on physical activity (PA) to patients with IHD. Such advice cons

S Sabrina Hoppe