Eur J Prev Cardiol. 2026 May 23:zwag267. doi: 10.1093/eurjpc/zwag267. Online ahead of print.ABSTRACTRandomized controlled trials (RCTs) remain the gold standard for causal inference in cardiovascular prevention but are often limited by cost, feasibility, and restricted generalizability. The rapid ex
Popul Health Manag. 2026 May 23:19427891261450803. doi: 10.1177/19427891261450803. Online ahead of print.ABSTRACTPrior work has shown that persons with disabilities have higher rates of poor cardiovascular outcomes than persons without disabilities. Little research has evaluated this relationship in
J Am Acad Orthop Surg Glob Res Rev. 2026 May 19;10(5). doi: 10.5435/JAAOSGlobal-D-25-00449. eCollection 2026 May 1.ABSTRACTOBJECTIVE: Fiberglass long leg casting is often used to treat specific lower extremity fracture patterns in children. However, cylindrical casting limits swelling, increasing ri
Clin Transl Med. 2026 May;16(5):e70703. doi: 10.1002/ctm2.70703.ABSTRACTBACKGROUND: The unpredictability of orthodontic tooth movement (OTM) and risks of root resorption stem from poorly understood mechanisms governing alveolar bone remodelling. Specifically, how macrophages transduce mechanical for
Kaohsiung J Med Sci. 2026 May 22:e70234. doi: 10.1002/kjm2.70234. Online ahead of print.ABSTRACTMyocardial ischemia/reperfusion (I/R) injury is characterized by cardiomyocyte death, excessive oxidative stress, inflammation, and ferroptosis, which collectively limit the efficacy of reperfusion therap
Cancer. 2026 Jun 1;132(11):e70465. doi: 10.1002/cncr.70465.ABSTRACTBACKGROUND: Mutations in cytokine receptor and JAK/STAT; Cy-JAK/STAT) signaling genes drive myeloproliferative neoplasms (MPNs) but remain incompletely characterized in acute myeloid leukemia (AML). The authors evaluated the prevalen
Eur J Heart Fail. 2026 May 22:xuag179. doi: 10.1093/ejhf/xuag179. Online ahead of print.ABSTRACTBACKGROUND AND AIMS: Hypertrophic cardiomyopathy (HCM) is characterized by increased risk of malignant ventricular arrhythmias (MVA) and heart failure (HF). There is increasing awareness that epicardial a
J Neurochem. 2026 May;170(5):e70472. doi: 10.1111/jnc.70472.ABSTRACTHypoxia-ischaemia and reperfusion (HI/R) damage is a result stemming from any event that interrupts the brain's blood supply, such as the occlusion of a blood vessel. In neurons, the molecular mechanisms involved in the HI/R cascade
Medicine (Baltimore). 2026 May 22;105(21):e49040. doi: 10.1097/MD.0000000000049040.ABSTRACTCardiac involvement is increasingly recognized in patients with community-acquired pneumonia (CAP). This study aimed to investigate the association between baseline troponin I levels and clinical outcomes, inc
Medicine (Baltimore). 2026 May 22;105(21):e49037. doi: 10.1097/MD.0000000000049037.ABSTRACTEarly risk stratification may support emergency department (ED) decision-making for patients hospitalized with heart failure (HF), yet commonly used tools may perform differently across clinically relevant out
Medicine (Baltimore). 2026 May 22;105(21):e49062. doi: 10.1097/MD.0000000000049062.ABSTRACTDelirium is a frequent and clinically consequential complication among patients admitted to the intensive care unit (ICU). Early risk stratification in patients with non-ST-segment elevation myocardial infarct
Medicine (Baltimore). 2026 May 22;105(21):e49049. doi: 10.1097/MD.0000000000049049.ABSTRACTEndoscopic retrograde cholangiopancreatography (ERCP) requires deep sedation, typically with propofol, because of its rapid onset and recovery time. However, propofol can cause respiratory and hemodynamic inst
Medicine (Baltimore). 2026 May 22;105(21):e48603. doi: 10.1097/MD.0000000000048603.ABSTRACTAcute exacerbation of chronic heart failure (CHF) is a major cause of recurrent hospitalization and mortality in heart failure patients. Accurate prediction of acute exacerbation of CHF risk is crucial for opt
Medicine (Baltimore). 2026 May 22;105(21):e48987. doi: 10.1097/MD.0000000000048987.ABSTRACTAbdominal aortic aneurysm (AAA) is a chronic degenerative disease characterized by localized aortic dilation and persistent inflammation. While neutrophil extracellular traps (NETs) are increasingly recognized
Medicine (Baltimore). 2026 May 22;105(21):e48986. doi: 10.1097/MD.0000000000048986.ABSTRACTBody mass index (BMI) reflects general adiposity, waist circumference (WC) and hip circumference (HC) indicate regional fat distribution, and total fat percentage (TFP) represents overall body fat composition,
Medicine (Baltimore). 2026 May 22;105(21):e48910. doi: 10.1097/MD.0000000000048910.ABSTRACTThe TyG index, a simple surrogate marker for insulin resistance, shows promise for predicting vascular complications in T2DM. This study evaluated its utility in predicting peripheral vascular complications an
Medicine (Baltimore). 2026 May 22;105(21):e48900. doi: 10.1097/MD.0000000000048900.ABSTRACTDepression is associated with increased cardiometabolic morbidity and mortality. However, the prognostic value of integrated biomarkers for mortality risk in this population is underexplored, particularly acro
Medicine (Baltimore). 2026 May 22;105(21):e48920. doi: 10.1097/MD.0000000000048920.ABSTRACTExisting studies suggest that cardiometabolic multimorbidity (CMM) affects cognitive function, but the role of systemic inflammation in this association remains unclear. Therefore, investigating the mechanisti
Medicine (Baltimore). 2026 May 22;105(21):e48945. doi: 10.1097/MD.0000000000048945.ABSTRACTPrior investigations have indicated an association between sedentary and physically active behaviors, tobacco and alcohol intake behaviors, and hemorrhoidal disease (HD). Yet, the causal relationship between t
Medicine (Baltimore). 2026 May 22;105(21):e48949. doi: 10.1097/MD.0000000000048949.ABSTRACTSmall dense low-density lipoprotein cholesterol is a better indicator in monitoring atherosclerotic cardiovascular disease. This study was designed to explore the distribution patterns of small dense low-densi
Medicine (Baltimore). 2026 May 22;105(21):e48859. doi: 10.1097/MD.0000000000048859.ABSTRACTCancer survivors face elevated risks of cerebrovascular complications, yet long-term mortality trends among adults who experience both cancer and stroke remain insufficiently defined. This study examined natio
Medicine (Baltimore). 2026 May 22;105(21):e49044. doi: 10.1097/MD.0000000000049044.ABSTRACTThe weight-adjusted waist index (WWI) and C-reactive protein (CRP) have been independently associated with multiple chronic conditions. Given that central adiposity drives systemic inflammation, and WWI serves
Medicine (Baltimore). 2026 May 22;105(21):e48871. doi: 10.1097/MD.0000000000048871.ABSTRACTCortical laminar necrosis (CLN) is a rare form of ischemic necrosis characterized by laminar damage primarily affecting the third to fifth cortical layers. CLN typically follows cerebral infarction but can als
Medicine (Baltimore). 2026 May 22;105(21):e48967. doi: 10.1097/MD.0000000000048967.ABSTRACTDiagnostic cerebral angiography is essential for the treatment of cerebrovascular disease. The conventional transfemoral approach (TFA) carries risks of vascular complications and longer recovery. The transrad
