EECP intervention and coronary flow reserve in chronic coronary syndrome: a protocol of a multicentre, randomised controlled study in China (ECP-Core Trial)

Trials. 2026 Jul 3. doi: 10.1186/s13063-026-09878-y. Online ahead of print.ABSTRACTBACKGROUND: Few non-invasive approaches are available for improving coronary function in intermediate-risk chronic coronary syndrome (CCS) patients. Over the past 30 years, enhanced external counterpulsation (EECP) ha

Y Yanlong Leng

Pistacia atlantica sub. Kurdica can improve insulin resistance in patients with non-alcoholic fatty liver disease: a randomized clinical trial

BMC Complement Med Ther. 2026 Jul 3. doi: 10.1186/s12906-026-05249-x. Online ahead of print.ABSTRACTBACKGROUND: Nonalcoholic fatty liver disease (NAFLD), also termed metabolic dysfunction‑associated fatty liver disease is a problem across the world. The most important factor of the increase in NAFLD

R Roghayeh Mostafaei

Cardiac-targeted delivery of miRNA via antioxidant nanozymes ameliorates cardiac dysfunction and fibrosis after myocardial infarction

J Nanobiotechnology. 2026 Jul 3. doi: 10.1186/s12951-026-04772-w. Online ahead of print.ABSTRACTDespite advances in reperfusion therapy, treatment outcomes for myocardial infarction (MI) remain limited by poor targeting specificity and insufficient bioavailability of therapeutic agents in the ischem

T Tong Yu

A putative SGLT-relevant mechanistic perspective on quercetin-3-O-glucoside and rutin in diabetic kidney disease

Diabetol Metab Syndr. 2026 Jul 3. doi: 10.1186/s13098-026-02233-w. Online ahead of print.ABSTRACTBACKGROUND: Type 2 diabetes mellitus (T2DM) is escalating worldwide and remains difficult to control durably, in part because progressive β-cell dysfunction undermines many therapies and because long-ter

D Dante Saksono Harbuwono

The lowest mitral valve area successfully treated by PTMC: a rare case

J Cardiothorac Surg. 2026 Jul 3. doi: 10.1186/s13019-026-04459-1. Online ahead of print.ABSTRACTWe present a detailed case of a 39-year-old male patient with severe, symptomatic rheumatic mitral stenosis who was successfully treated with percutaneous transvenous mitral commissurotomy (PTMC) at Milad

M Mohammad Hadi Mansouri

Impact of early tracheostomy in infratentorial lesions trial: rationale and design

Trials. 2026 Jul 3. doi: 10.1186/s13063-024-08682-w. Online ahead of print.ABSTRACTBACKGROUND: Tracheostomy is a common procedure in patients who undergo surgical resection of infratentorial lesions. However, the optimal timing and high-risk factors for tracheostomy remain unknown.METHODS: Value of

S Song Han

Efficacy of leflunomide in active Takayasu arteritis: a randomized double-blind placebo-controlled trial subtitle: Takayasu arteritis clinical trial in China (TACTIC)

BMC Med. 2026 Jul 3. doi: 10.1186/s12916-026-05009-1. Online ahead of print.ABSTRACTBACKGROUND: Leflunomide (LEF) shows promising effect in Takayasu arteritis (TAK), but evidence from randomized controlled trials is lacking. This study aims to investigate the efficacy and safety of LEF versus placeb

Y Ying Sun

Predictive value of multivariate models of quantitative myocardial movement parameters for acute myocardial infarction in elderly patients with coronary artery disease

BMC Cardiovasc Disord. 2026 Jul 3. doi: 10.1186/s12872-026-06196-8. Online ahead of print.ABSTRACTOBJECTIVE: This study aimed to investigate the association of multivariate models encompassing quantitative myocardial movement parameters with the risk of subsequent acute myocardial infarction (AMI) w

Q Qiang Chen

Heterogeneity in blood pressure and weight trajectories and associated mortality risk among hypertensive patients in rural South Africa: findings from cluster analysis of longitudinal clinical record linkage data

BMC Public Health. 2026 Jul 3. doi: 10.1186/s12889-026-27124-7. Online ahead of print.ABSTRACTBACKGROUND: Hypertension and obesity are the leading risk factors for cardiovascular disease (CVD), causing over ten million annual preventable deaths globally. Understanding individual differences in how b

J Jean Juste Harrisson Bashingwa

Post-transplant diabetes mellitus in Sudanese kidney transplant recipients: determinants and clinical outcomes from a retrospective cohort study

BMC Nephrol. 2026 Jul 3. doi: 10.1186/s12882-026-05184-6. Online ahead of print.ABSTRACTBACKGROUND: Post-transplant diabetes mellitus (PTDM) is a common metabolic complication after kidney transplantation and has been linked to adverse long-term outcomes. Evidence from sub-Saharan Africa remains lim

M Mazin M T Shigidi

Angiogenin alleviates lipotoxicity-induced impairment of skin wound healing

Cell Mol Biol Lett. 2026 Jul 3. doi: 10.1186/s11658-026-00970-4. Online ahead of print.ABSTRACTLipotoxicity-induced endothelial dysfunction impairs wound healing in obesity and type 2 diabetes, yet the underlying mechanisms remain elusive. While Angiogenin promotes endothelial function, its role und

M Min Fu

Prospective randomized controlled trial of computer simulation versus high-fidelity mannequin simulation in advanced cardiovascular life support (ACLS) training for anesthesiology novice clinicians

BMC Anesthesiol. 2026 Jul 4. doi: 10.1186/s12871-026-04080-8. Online ahead of print.ABSTRACTBACKGROUND: Traditionally, cardiopulmonary resuscitation (CPR) and advanced cardiovascular life support (ACLS) training programs have relied heavily on paper-based instructional materials and multimedia theor

J Jiafeng Yu

Reduced meat and dairy consumption improves health, environmental and most nutritional outcomes without increasing diet costs among Scottish adults

Nat Food. 2026 Jul 3. doi: 10.1038/s43016-026-01384-3. Online ahead of print.ABSTRACTShifting diets away from high levels of meat and dairy is increasingly considered an important part of climate mitigation, yet the best pathways for achieving these reductions without compromising nutrition, health

J Joe Kennedy

Impact of Higher Versus Lower Blood Pressure Targets on Pulmonary Vascular Hemodynamics During Intensive Care After Out-of-Hospital Cardiac Arrest

Acta Anaesthesiol Scand. 2026 Aug;70(7):e70294. doi: 10.1111/aas.70294.ABSTRACTBACKGROUND: Hemodynamic management after out-of-hospital cardiac arrest (OHCA) is critical, yet the impact of vasopressor-driven mean arterial pressure (MAP) targets on pulmonary circulation and right ventricular (RV) fun

S Shira K Hendin

Restoring anisotropy after myocardial injury: strategies to align transplanted human induced pluripotent stem-cell-derived cardiomyocytes

Exp Mol Med. 2026 Jul 3. doi: 10.1038/s12276-026-01773-5. Online ahead of print.ABSTRACTHuman induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) represent a promising cell source for cardiac regeneration, yet their therapeutic efficacy remains limited by poor structural organization an

Y Yura Son

Integrative proteogenomic analyses identify plasma proteins that impact the risk of ischemic stroke

Commun Med (Lond). 2026 Jul 3;6(1):374. doi: 10.1038/s43856-026-01734-z.ABSTRACTBACKGROUND: Understanding the proteins implicated in the pathogenesis of ischemic stroke is important for elucidating disease mechanisms and informing prevention strategies. In this study, we aim to identify plasma prote

L Lazaros Belbasis

PCSK5 promotes angiogenesis and cardiac repair after myocardial infarction

Nat Commun. 2026 Jul 3;17(1):5733. doi: 10.1038/s41467-026-72148-7.ABSTRACTPCSK5 (proprotein convertase subtilisin/kexin 5) is essential for heart development. However, its role in myocardial infarction (MI) remains unexplored. In this study, we found that the plasma levels of PCSK5 were elevated in

J Jieyu Guo

Platelet-to-albumin ratio and postoperative bleeding after endovascular treatment of intracranial aneurysms: A retrospective cohort study

J Int Med Res. 2026 Jul;54(7):3000605261448081. doi: 10.1177/03000605261448081. Epub 2026 Jul 3.ABSTRACTBackgroundPostoperative bleeding in patients with intracranial aneurysms remains a serious complication associated with high mortality. The platelet-to-albumin ratio, reflecting thrombotic potenti

H Hong Liu

Silymarin Reverses Seizure-Precipitating Effects of Alcohol and Associated Psychiatric Comorbidities, and Neurotoxicity in Pentylenetetrazol Pre-Kindled Mice

Neurotox Res. 2026 Jul 4;44(4):30. doi: 10.1007/s12640-026-00804-3.ABSTRACTHeavy alcohol consumption has multiple negative cognitive, psychological, and neurobiological consequences for people with epilepsy. However, the psychopharmacological interactions remain unclear with limited therapeutic inte

B Benneth Ben-Azu

Serum ferritin as a predictor of major adverse cardiovascular events in Takayasu arteritis: a two-center retrospective cohort study

Clin Rheumatol. 2026 Jul 4. doi: 10.1007/s10067-026-08275-9. Online ahead of print.ABSTRACTOBJECTIVES: Elevated serum ferritin levels predict adverse outcomes in many autoimmune diseases. However, its clinical significance in Takayasu arteritis (TAK) is not clear. This study aimed to evaluate the pr

W Weiping Ci

Early multimodal predictors of good neurological outcome in comatose patients after cardiac arrest: a prospective single-center cohort study

Neurol Sci. 2026 Jul 4;47(8):608. doi: 10.1007/s10072-026-09214-x.ABSTRACTBACKGROUND AND OBJECTIVES: Post-cardiac arrest (CA) prognostication primarily focuses on predicting poor outcome, whereas early markers of good prognosis remain less explored. We aimed to identify early predictors of favorable

G Giovanna De Marco

Diagnostic Tests for Stage B Heart Failure

Curr Cardiol Rep. 2026 Jul 4;28(1):65. doi: 10.1007/s11886-026-02389-x.ABSTRACTPURPOSE OF THE REVIEW: To provide an overview of diagnostic tests for Stage B heart failure (SBHF), synthesizing evidence from guidelines and clinical studies.RECENT FINDINGS: Advances in diagnostic technologies have expa

H Hai Nguyen Ngoc Dang

Advancing cardiovascular prevention : Evidence-based design of healthy and sustainable food environments

Herz. 2026 Jul 3. doi: 10.1007/s00059-026-05387-5. Online ahead of print.ABSTRACTMalnutrition is among the leading modifiable risk factors for cardiovascular diseases worldwide. Current international guidelines consistently recommend predominantly plant-based dietary patterns rich in vegetables, fru

N Niklas Oppenrieder

Effects of air pollution on cardiovascular health

Herz. 2026 Jul 3. doi: 10.1007/s00059-026-05388-4. Online ahead of print.ABSTRACTAmbient air pollution is a leading modifiable environmental determinant of cardiovascular morbidity and mortality worldwide. Long-term and short-term exposure to fine particulate matter and traffic-related pollutants is

M Marin Kuntic