The Value of Anti-Drug Antibody Detection in Discriminating Patients from Healthy Controls and Predicting the Gross Motor Functional State in Patients with Pompe Disease

Iran J Allergy Asthma Immunol. 2026 Feb 1;25(2):212-221. doi: 10.18502/ijaai.v25i2.20800.ABSTRACTAnti-recombinant human acid α-glucosidase (anti-rhGAA) antibody formation is a major challenge in patients with Pompe disease receiving enzyme replacement therapy (ERT). The clinical significance of thes

S Solmaz Aziz-Ahari

Acute Effects of Passive Heat Exposure on Vascular Function and Exercise Capacity in Patients with Chronic Kidney Disease

Am J Physiol Heart Circ Physiol. 2026 May 11. doi: 10.1152/ajpheart.00020.2026. Online ahead of print.ABSTRACTBACKGROUND. Vascular dysfunction and exercise intolerance contribute to chronic kidney disease (CKD) related cardiovascular disease. Passive heat exposure provides a physiological stimulus f

D Domenico A Chavez

Viral suppression is associated with rising NT-proCNP levels and reduced systemic inflammation in people living with HIV

Infection. 2026 May 11. doi: 10.1007/s15010-026-02812-z. Online ahead of print.ABSTRACTBACKGROUND: People living with HIV (PLWH) have an increased risk of cardiovascular disease that persists despite effective antiretroviral therapy (ART) and viral suppression. Chronic inflammation and endothelial d

I Istvan Bojti

Helicobacter pylori and Porphyromonas gingivalis as candidate microbial biomarkers linking periodontal disease, MASLD, and cardiovascular risk

No abstractInfection. 2026 May 11. doi: 10.1007/s15010-026-02816-9. Online ahead of print.NO ABSTRACTPMID:42113460 | DOI:10.1007/s15010-026-02816-9

J Jannis Kountouras

Fuzheng Jiedu Tongluo Granule Alleviates Cerebral Ischemia/reperfusion Injury-induced Inflammation By Inhibiting Drp1-mediated TXNIP/NLRP3 Pathway

Mol Neurobiol. 2026 May 11;63(1):620. doi: 10.1007/s12035-026-05920-x.ABSTRACTInflammatory response is considered a critical component in developing cerebral ischemia/reperfusion injury (CI/RI). Dynamin-related protein 1 (Drp1) performs an essential role in initiating and advancing CI/RI-induced inf

Y Yajie Chen

Kidney-limited thrombotic microangiopathy caused by relative hypertension in a hemodynamically vulnerable kidney allograft, mimicking malignant hypertension

CEN Case Rep. 2026 May 11;15(3):86. doi: 10.1007/s13730-026-01120-7.ABSTRACTMalignant hypertension is traditionally defined as severe systemic blood pressure elevation accompanied by end-organ damage. In kidney transplant recipients, however, kidney allografts may be particularly vulnerable to hyper

S Shinnosuke Sugihara

Repositioning of exercise treadmill testing in contemporary chest pain management

Int J Cardiovasc Imaging. 2026 May 11. doi: 10.1007/s10554-026-03728-3. Online ahead of print.ABSTRACTBACKGROUND: Chest pain evaluation has become increasingly imaging-led with widespread use of coronary CT angiography (CTCA) and stress imaging (e.g., CMR, stress echocardiography). In this context,

X Xiaoqin Xue

Caffeic acid phenethyl ester attenuates phenotypic switching and inflammation in abdominal aortic aneurysm via the NF-κB pathway

Mol Biol Rep. 2026 May 11;53(1):744. doi: 10.1007/s11033-026-11924-6.ABSTRACTBACKGROUND: In our previous animal experiments, we found that caffeic acid phenethyl ester (CAPE) inhibited the early formation of elastase-induced abdominal aortic aneurysms (AAA) in rats. However, its efficacy in the angi

Y Yuanyuan Gu

Targeting Siglec-E Modulates Macrophage Polarization to Attenuate Cardiac Remodeling After Myocardial Infarction

J Cardiovasc Transl Res. 2026 May 11;19(1):52. doi: 10.1007/s12265-026-10771-x.ABSTRACTAdverse cardiac remodeling after myocardial infarction (MI) is a major cause of heart failure. Macrophage polarization plays a pivotal role in this process. Siglec-E, an immunoregulatory molecule expressed on myel

Y Yuan Li

Targeting endoplasmic reticulum stress for neuroprotection in ischemia-reperfusion injury: mechanisms and therapeutic approaches

Mol Biol Rep. 2026 May 11;53(1):734. doi: 10.1007/s11033-026-11915-7.ABSTRACTThe pathological condition known as ischemia reperfusion injury (IRI) is characterized by an initial restriction in the amount of blood supply followed by reperfusion which paradoxically aggravates irreversible neuronal dam

N Nazrana Payal

Galectin-3 binding protein is upregulated in heart failure with preserved ejection fraction and associated with endothelial nitric oxide synthase deficiency

Geroscience. 2026 May 11. doi: 10.1007/s11357-026-02314-8. Online ahead of print.ABSTRACTHeart failure with preserved ejection fraction (HFpEF) is a cardiometabolic syndrome strongly associated with aging, systemic inflammation and endothelial dysfunction, in which impaired endothelial nitric oxide

R Rosalinda Madonna

Mechanisms driving thoracic aortic aneurysm instability

Biomech Model Mechanobiol. 2026 May 11;25(3):43. doi: 10.1007/s10237-026-02054-w.ABSTRACTThoracic aortic aneurysms arise from a combination of biological and mechanical factors. Current clinical guidelines use size and rate of expansion to stratify risk, but such metrics do not necessarily predict i

E Erica L Schwarz

Associations of Overweight and Obesity Indicators with Cardiometabolic Risk Profile in Children and Adolescents with Congenital Heart Disease

Pediatr Cardiol. 2026 May 11. doi: 10.1007/s00246-026-04295-z. Online ahead of print.ABSTRACTThis study aimed to compare the cardiometabolic risk profile between overweight or obese and normal weight and to investigate the influence of overweight and obesity indicators on cardiometabolic risk profil

M Michele Honicky

Calcium Signaling Dysregulation in Diabetic Cardiomyopathy: Roles of STIM and Orai Channels

Diabetes mellitus is a major metabolic disorder that significantly increases the risk of cardiovascular disease. Altered calcium (Ca^(2+)) homeostasis, particularly through store-operated calcium entry (SOCE), has emerged as a critical pathway linking diabetes with cardiac dysfunction. Evidence indi

T Tarik Smani

Experimental Models for Studying Cardiovascular Dysfunction in Metabolic Syndrome

Handb Exp Pharmacol. 2026 May 12. doi: 10.1007/164_2026_800. Online ahead of print.ABSTRACTMetabolic syndrome (MetS) encompasses an interconnected set of risk factors, including abdominal obesity, insulin resistance, hypertension, dyslipidemia, and systemic inflammation, all of which significantly i

J Jade L Taylor

Extracorporeal membrane oxygenation, acute kidney injury, fluid balance, and continuous renal replacement therapy: Acute Disease Quality Initiative (ADQI) and Extracorporeal Life Support Organization (ELSO) joint consensus conference

Intensive Care Med. 2026 May 6. doi: 10.1007/s00134-026-08440-3. Online ahead of print.ABSTRACTExtracorporeal membrane oxygenation (ECMO) is increasingly being utilized for life-threatening cardiac and/or respiratory failure refractory to conventional treatment. Acute kidney injury (AKI) and fluid b

K Katja M Gist

Do potentially toxic elements drive antimicrobial resistance? A systematic review of co-selection mechanisms and environmental reservoirs

Environ Monit Assess. 2026 May 11;198(6):574. doi: 10.1007/s10661-026-15415-w.ABSTRACTAntimicrobial resistance (AMR) is a paramount global health threat. While antibiotic misuse is a recognized driver, other environmental pollutants, particularly non-biodegradable heavy metals, are increasingly impl

C Caroline Nakirijja

Dyslipidemia as a key nexus linking depression and aging acceleration: unraveling the mediating role of lipid accumulation product (LAP)

Eur Arch Psychiatry Clin Neurosci. 2026 May 11. doi: 10.1007/s00406-026-02258-2. Online ahead of print.ABSTRACTOBJECTIVE: Although depression and biological aging share dyslipidemia as a common pathological feature, the extent to which dyslipidemia is involved in their association remains unclear. T

L Li Zhang

Life's Essential 8: Cardiovascular Health Assessment Among Brazilian University Workers

Workplace Health Saf. 2026 May 11:21650799261440278. doi: 10.1177/21650799261440278. Online ahead of print.ABSTRACTBACKGROUND: The American Heart Association has introduced Life's Essential 8 (LE8) for primary cardiovascular disease prevention. This study assessed cardiovascular health (CVH) using L

L Leila Tássia Pagamicce

AI-driven Abdominal Aortic Calcification Extracted From Contrast-enhanced CT Is Predictive of All-cause Mortality and Cardiovascular Events in a Large Adult Population

J Comput Assist Tomogr. 2026 May 11. doi: 10.1097/RCT.0000000000001876. Online ahead of print.ABSTRACTOBJECTIVE: To assess the utility of AI-driven quantification of abdominal aortic calcification (AAC) extracted from contrast-enhanced CT (CECT) scans using a fully automated AI tool for predicting a

L Louis A Hinshaw

In-Human OCT Evidence of Acute Transfer and Persistence of Crystal-Like Deposits After Sirolimus-Coated Balloon Angioplasty

No abstractJACC Cardiovasc Interv. 2026 May 11:S1936-8798(26)01021-6. doi: 10.1016/j.jcin.2026.03.006. Online ahead of print.NO ABSTRACTPMID:42112974 | DOI:10.1016/j.jcin.2026.03.006

V Victor Alfonso Jimenez Diaz

Association of Admission Glucose-to-Lymphocyte Ratio With 90-Day Functional Outcome in Patients With Acute Ischemic Stroke Treated With Intravenous Thrombolysis

Brain Behav. 2026 May;16(5):e71484. doi: 10.1002/brb3.71484.ABSTRACTBACKGROUND: The glucose-to-lymphocyte ratio (GLR), a composite biomarker reflecting metabolic and immune-inflammatory status, has shown prognostic value in several clinical settings. However, its relevance in patients with acute isc

D Dong Zhang

To what extent is air pollution associated with cardiorespiratory hospitalisations across Australia? A whole-of-population ecological study

Public Health Res Pract. 2026 Jun 25;36(2):PU25054. doi: 10.1071/PU25054.ABSTRACTOBJECTIVES AND IMPORTANCE OF STUDY: This study aimed to examine the extent to which residential ambient air pollution across Australia, globally a relatively low-pollution setting, is associated with cardiovascular and

K Kate Lycett

Predicting Home Exercise Adherence after Ischemic Stroke: Development and Validation of a Web-Based Nomogram

Brain Behav. 2026 May;16(5):e71482. doi: 10.1002/brb3.71482.ABSTRACTBACKGROUND: Poor adherence to home-based functional exercises can substantially hinder recovery after ischemic stroke. This study aimed to develop and validate a web-based predictive nomogram to identify patients with ischemic strok

W Wenbo Li