Traditional Rehabilitation Experiences, Unmet Needs, and Perspectives on Virtual Reality-Based Rehabilitation Among Patients With Stroke in China: Qualitative Thematic Analysis and Semistructured Interview Study

J Med Internet Res. 2026 Feb 2;28:e84532. doi: 10.2196/84532.ABSTRACTBACKGROUND: Traditional stroke rehabilitation is facing challenges, and virtual reality (VR)-based rehabilitation is a promising solution. However, results from studies focusing on VR-based stroke rehabilitation remain inconsistent

X Xite Zheng

Evaluating Prehospital Stroke Scales for Large Vessel Occlusion: A Systematic Review and Network Meta-Analysis

Neurology. 2026 Feb 24;106(4):e214484. doi: 10.1212/WNL.0000000000214484. Epub 2026 Feb 2.ABSTRACTBACKGROUND AND OBJECTIVES: Ischemic stroke remains a leading cause of death and disability worldwide, with large vessel occlusion (LVO) accounting for a disproportionate share of poststroke morbidity. E

N Noah Lee Ahmad Nawabi

Addressing Gaps in the Hypertension and Diabetes Care Continuum in Rural Bangladesh Through Digital Technology Supported Decentralized Primary Care: Study Protocol and Baseline Results for a Hybrid Effectiveness-Implementation Trial

JMIR Res Protoc. 2026 Feb 2;15:e71696. doi: 10.2196/71696.ABSTRACTBACKGROUND: Hypertension and diabetes are very common, interrelated chronic conditions. Awareness, diagnosis, treatment, and control rates of these conditions remain low, and access to quality care-particularly in rural areas-is a per

W Wubin Xie

Estimating the incidence of heart failure: Insights from an illness-death model using statutory health insurance data from 70 million people in Germany

PLoS One. 2026 Feb 2;21(2):e0341810. doi: 10.1371/journal.pone.0341810. eCollection 2026.ABSTRACTINTRODUCTION: Heart Failure (HF) is a considerable public health issue that affects more than 64 million people worldwide, with a prevalence of 1% to 3% in Western industrialized countries. However, reli

M Mike Wagner

Combined assessment of pulmonary artery pulsatility index and pulmonary arterial capacitance for risk stratification following transcatheter aortic valve implantation

Acta Cardiol. 2026 Feb 2:1-7. doi: 10.1080/00015385.2026.2621562. Online ahead of print.ABSTRACTBACKGROUND: Right heart haemodynamics, including right ventricular function and pulmonary arterial capacitance (PAC), are important prognostic determinants in cardiovascular disease. However, their combin

Y Yuta Ozaki

Defining an Optimal Result of Transcatheter Tricuspid Valve Intervention: Results From the Tri-QOL Study

Circulation. 2026 Feb 3;153(5):310-318. doi: 10.1161/CIRCULATIONAHA.125.076542. Epub 2026 Feb 2.ABSTRACTBACKGROUND: Recent randomized trials have demonstrated that for patients with severe tricuspid regurgitation (TR), transcatheter tricuspid valve interventions (TTVI) improve patients' symptoms, fu

S Suzanne V Arnold

In-silico characterization of deleterious non-synonymous SNPs in the human S1PR1 gene reveals structural instability and altered ligand affinity

PLoS One. 2026 Feb 2;21(2):e0339370. doi: 10.1371/journal.pone.0339370. eCollection 2026.ABSTRACTS1PR1 is a G protein-coupled receptor that plays a key role in regulating lymphocyte trafficking, immune response, cardiovascular system function, cell proliferation and survival, tumor angiogenesis, and

S Sangram Biswas

Coronary Artery Spasm in Cardiac Arrest Survivors

Europace. 2026 Feb 2:euag020. doi: 10.1093/europace/euag020. Online ahead of print.ABSTRACTCoronary artery spasm can be life-threatening. Clinically significant complications include myocardial infarction, ventricular arrhythmias and sudden cardiac arrest. Although challenging to diagnose, new inter

D Dorte Stavnem

A Nomogram to Predict of Epidural Blood Patch Treatment Failure in Patients With Spontaneous Intracranial Hypotension and Subdural Hematoma

Pain Physician. 2026 Jan;29(1):E29-E42.ABSTRACTBACKGROUND: Subdural hematoma (SDH) is a frequent and serious complication of spontaneous intracranial hypotension (SIH), often requiring timely intervention. An epidural blood patch (EBP) is widely recognized as the preferred interventional treatment f

H Hua Huang

The effect of oral ciprofloxacin at conventional doses on the QT interval in a tertiary outpatient setting

J Antimicrob Chemother. 2026 Feb 2;81(3):dkag020. doi: 10.1093/jac/dkag020.ABSTRACTAIMS: Ciprofloxacin has been demonstrated to prolong QT intervals at higher doses beyond those used in conventional practice. We investigated the effect of ciprofloxacin on the QT interval by examining the difference

W Weber Liu

Impact of an infectious disease specialist-led antimicrobial stewardship program and consultations during multiple antimicrobial shortages: A bayesian structural time-series analysis

PLoS One. 2026 Feb 2;21(2):e0340599. doi: 10.1371/journal.pone.0340599. eCollection 2026.ABSTRACTSince antimicrobial shortages are becoming common owing to manufacturing issues and sudden demand, individualized antimicrobial optimization by infectious disease specialists is essential. We evaluated t

N Naoya Itoh

Electroacupuncture Orchestrates Intestinal Flora Remodeling: A Step Forward in Alleviating High Salt-Induced Vasculopathy

J Vis Exp. 2026 Jan 13;(227). doi: 10.3791/69783.ABSTRACTThis study aims to investigate the therapeutic potential and mechanisms of electroacupuncture (EA) in alleviating vascular dysfunction caused by high-salt diets, with a focus on gut microbiota modulation. We randomly divided 21 rats into Norma

Y Yuxian Zhang

Feasibility of Baseline cardIac investiGation in awake elepHants (Elephas mAximus) using tRansThoracic echocardiography: The BIG HEART study

PLoS One. 2026 Feb 2;21(2):e0333463. doi: 10.1371/journal.pone.0333463. eCollection 2026.ABSTRACTINTRODUCTION: Cardiovascular diseases are common in elephants, but most cases are diagnosed only postmortem. Transthoracic echocardiography (TTE) is widely used in domestic and captive animals, although

A Antonin Boutibou

The novel mineralocorticoid receptor modulator balcinrenone protects against diet-induced cardiac microvascular dysfunction and plasma potassium elevation in mouse models

PLoS One. 2026 Feb 2;21(2):e0341078. doi: 10.1371/journal.pone.0341078. eCollection 2026.ABSTRACTOveractivation of the mineralocorticoid receptor (MR) promotes tissue remodeling in patients with heart failure (HF) and/or chronic kidney disease (CKD). These patients may benefit from MR antagonists (M

M Matthew J Wolf

Identification and characterization of tryptophan metabolism-related genes in carotid artery plaques

PLoS One. 2026 Feb 2;21(2):e0341122. doi: 10.1371/journal.pone.0341122. eCollection 2026.ABSTRACTCardiovascular and cerebrovascular diseases, often caused by atherosclerosis, are the stern cause of death worldwide, and carotid plaque play a crucial role in the development of these diseases. Tryptoph

X Xiaodong Jia

Community voices: Exploring beliefs, attitudes, practices and recommendations for improving stroke prevention and stroke care in rural and urban communities in Nigeria

PLoS One. 2026 Feb 2;21(2):e0322157. doi: 10.1371/journal.pone.0322157. eCollection 2026.ABSTRACTINTRODUCTION: Globally, stroke is a leading cause of mortality with higher incidence in low- and middle-income countries. However, stroke beliefs and knowledge among community partners are essential cons

E Ezinne O Uvere

Implantation of Left Ventricular Assist Device (LVAD) in Juvenile Landrace Swine: A LVAD Implantation Model of Pediatric Heart Failure

J Vis Exp. 2026 Jan 16;(227). doi: 10.3791/69151.ABSTRACTA pediatric left ventricular assist device (LVAD) implantation model was established to simulate pediatric LVAD support and research the mechanism of heart reverse remodeling. Heart failure (HF) is a prevalent global cardiovascular disease. LV

W Wei Wang

Prognostic Implications of Elevated Left Ventricular Ejection Fraction in Patients with Sepsis

J Vis Exp. 2026 Jan 16;(227). doi: 10.3791/69647.ABSTRACTThe role of left ventricular systolic function as a prognostic marker for sepsis patients remains an area of ongoing research and debate. The present investigation exhibited the comprehensive evaluation of the relationship between different le

W Weibin You

Subperiosteal Drain Insertion and Anchorage after Single Burr Hole Evacuation of Chronic Subdural Hematoma

J Vis Exp. 2026 Jan 16;(227). doi: 10.3791/69808.ABSTRACTSymptomatic chronic subdural hematoma is treated by surgical evacuation followed by drain insertion for post-operative drainage. There is no international consensus on the location of the drain (subdural or subperiosteal), the type of drainage

J Jacob Holmen Terkelsen

Lansoprazole Improves Long-Term Neurological Function via Alleviating Intestinal Injury in a Mouse Model of Intracerebral Hemorrhage

J Vis Exp. 2026 Jan 16;(227). doi: 10.3791/69596.ABSTRACTIntracerebral hemorrhage (ICH) can compromise the gastrointestinal tract and trigger intestinal injury, contributing to poor clinical outcomes. This study investigated the effects of lansoprazole on intestinal injury and neurological function

Y Yucun Wang

Accurate Heart Sound Segmentation with Temporal Convolutional Network-Enhanced Duration Hidden Markov Model and Adaptive Calibration

IEEE Trans Biomed Eng. 2026 Feb 2;PP. doi: 10.1109/TBME.2026.3660309. Online ahead of print.ABSTRACTOBJECTIVE: Accurate segmentation of heart sound signal stages is critical in cardiovascular disease analysis.METHODS: This study proposed the integration of a duration hidden Markov model (DHMM) with

K Kaichuan Yang

A Mouse Model of Donor Heart Lymphatic Ablation via Electrocautery for Transplantation Research

J Vis Exp. 2026 Jan 16;(227). doi: 10.3791/69959.ABSTRACTAlthough cardiac lymphatic vessels have garnered increasing attention in recent years, the relationship between the donor cardiac lymphatic system and acute rejection in heart transplantation remains to be elucidated. Cardiac electrophysiologi

P Peiyuan Li

Strategies in Caring for Patients Living With Heart Failure in Rural Communities: A Systematic Review of the Literature

Fam Community Health. 2026 Feb 2. doi: 10.1097/FCH.0000000000000452. Online ahead of print.ABSTRACTHeart failure (HF) is a chronic disease with increasing prevalence, with rural communities having HF worse outcomes and higher mortality. The aim of this systematic review is to consolidate and evaluat

S Stephen A Clarkson

Periodontal Disease and Infertility: Probing the Depths of This Potential Connection

Compend Contin Educ Dent. 2025 Oct;46(9):423-428.ABSTRACTInfertility is a complex condition affecting both males and females. While the contributing causes are known to be multifactorial, the prevalence of infertility continues to rise. Recent research explores the potential relationship of periodon

K Kallie Krueger