Platelet RIP2 Limits Dense Granule Release and Thrombosis via DOCK8-Cdc42

Arterioscler Thromb Vasc Biol. 2026 Jun 11. doi: 10.1161/ATVBAHA.125.323791. Online ahead of print.ABSTRACTBACKGROUND: RIP2 (receptor-interacting protein kinase 2) is an essential mediator of inflammation and innate immunity downstream of PRRs (pattern recognition receptors). Platelets express RIP2,

J Jianjun Zhang

Microfibril Denudation Marks Early Aortic Vulnerability in SMAD3 Variant Carriers: A Multigenerational Study

Arterioscler Thromb Vasc Biol. 2026 Jun 11. doi: 10.1161/ATVBAHA.126.324690. Online ahead of print.ABSTRACTBACKGROUND: Individuals with Loeys-Dietz syndrome 3 are at risk for thoracic aortic dissection even if their aortas are not substantially dilated. A pathogenic variant of SMAD3 is a genetic tri

P Paulina M Kowalewska

Pharmacological and genetic modulation of IL-32 expression in intestinal epithelial cells does not impact HIV-1 outgrowth in co-cultured CD4+ T-cells

Front Immunol. 2026 May 26;17:1769388. doi: 10.3389/fimmu.2026.1769388. eCollection 2026.ABSTRACTBACKGROUND: The crosstalk between intestinal epithelial cells (IEC) and CD4+ T-cells is essential for the maintenance of mucosal homeostasis, but its role in governing HIV-1 latency versus reactivation i

E Etiene Moreira Gabriel

The immune-cardiovascular metabolic circuitry in myocardial ischemia-reperfusion injury: from metabolic signal release to spatiotemporal reprogramming

Front Immunol. 2026 May 26;17:1848067. doi: 10.3389/fimmu.2026.1848067. eCollection 2026.ABSTRACTMyocardial ischemia-reperfusion injury (MIRI) remains a major driver of infarct expansion, adverse remodeling, and poor outcomes after reperfusion therapy, yet mechanism-based treatments remain limited.

C Conghao Tan

Correction: Anti-β2GPI IgG display a broad reactivity against different β2GPI domains beyond domain 1: results from the APS ACTION and multi-center Italian cohorts

Front Immunol. 2026 May 26;17:1879170. doi: 10.3389/fimmu.2026.1879170. eCollection 2026.ABSTRACT[This corrects the article DOI: 10.3389/fimmu.2026.1809192.].PMID:42273675 | PMC:PMC13248120 | DOI:10.3389/fimmu.2026.1879170

C Claudia Grossi

Influenza vaccination and cardiovascular and respiratory outcomes in high-risk populations: an umbrella review of systematic reviews and meta-analyzes

Front Immunol. 2026 May 26;17:1798398. doi: 10.3389/fimmu.2026.1798398. eCollection 2026.ABSTRACTBACKGROUND: Influenza infection is an important trigger of acute cardiovascular events and respiratory decompensation in vulnerable populations. Although influenza vaccination may reduce cardiopulmonary

C Chengyan Jin

Reasons for referral to a social prescribing program through the COVID-19 pandemic and associated factors: a cross-sectional study in Portugal

Front Public Health. 2026 May 26;14:1726269. doi: 10.3389/fpubh.2026.1726269. eCollection 2026.ABSTRACTINTRODUCTION: Social prescribing (SP) links patients with non-medical needs affecting their health to services and activities within the community as a strategy to prevent disease and promote healt

L Louíse Viecili Hoffmeister

Latent profile and associated factors of digital health literacy among patients with coronary heart disease: a cross-sectional study

Front Public Health. 2026 May 26;14:1844333. doi: 10.3389/fpubh.2026.1844333. eCollection 2026.ABSTRACTOBJECTIVE: This study aims to explore the potential characteristics and associated factors of digital health literacy among patients with coronary heart disease, and to guide targeted intervention

L Lan Luo

Urban Waste Management, Air Quality, and Public Health: Assessing the Health Burden of Rapid Urbanization in Sub-Saharan Africa

China CDC Wkly. 2026 Jun 5;8(23):730-738. doi: 10.46234/ccdcw2026.118.ABSTRACTRapid urbanization in sub-Saharan Africa (SSA) is placing increasing pressure on waste management systems and urban air quality, with significant health implications. This study integrates cross-city analysis of waste syst

C Chukwuemeka John

One-year outcomes of thoracic endovascular stent graft repair for acute type B aortic penetrating ulcer combined with antiplatelet drugs

Front Cardiovasc Med. 2026 May 26;13:1676128. doi: 10.3389/fcvm.2026.1676128. eCollection 2026.ABSTRACTOBJECTIVE: The aim of this study was to investigate the 12-month clinical outcomes and 6-month morphological changes of acute penetrating aortic ulcers (PAUs) after thoracic endovascular aortic rep

Z Zhan-Kui Du

Performance of predictive scores for in-hospital mortality in surgical infective endocarditis: a retrospective cohort study

Front Cardiovasc Med. 2026 May 26;13:1829289. doi: 10.3389/fcvm.2026.1829289. eCollection 2026.ABSTRACTBACKGROUND: Infective endocarditis (IE) carries high surgical mortality, particularly in Latin American populations where validated prediction models are scarce. Although EuroSCORE II, RISK-E, and

P Paula Ximena Pavia-Velandia

Prognostic value of CTI for major adverse cardiovascular events in patients With ST-elevation myocardial infarction after primary percutaneous coronary intervention

Front Cardiovasc Med. 2026 May 26;13:1832830. doi: 10.3389/fcvm.2026.1832830. eCollection 2026.ABSTRACTMETHODS: A total of 618 STEMI patients who underwent PCI were retrospectively enrolled. The primary endpoint was 1-year MACE. Feature selection was performed using the Boruta algorithm. Multivariab

Q Qiang Zhao

Enhanced long-term outcomes with laparoscopic bariatric surgery in patients with severe obesity and metabolic dysfunction-associated steatotic liver disease: a retrospective cohort study

Hepatobiliary Surg Nutr. 2026 Jun 1;15(3):67. doi: 10.21037/hbsn-24-529. Epub 2025 Mar 26.ABSTRACTBACKGROUND: Bariatric surgery is a potential treatment for weight loss in patients with metabolic dysfunction-associated steatotic liver disease (MASLD) and severe obesity. However, the impact of bariat

X Xinrong Zhang

Clinical Significance of the C-Reactive Protein-Triglyceride-Glucose Index in Cardiovascular Disease, Stroke, Cardiovascular-Kidney-Metabolic Syndrome, Cancer, Diabetes, and Osteoporosis: A Narrative Review

Int J Gen Med. 2026 Jun 5;19:614184. doi: 10.2147/IJGM.S614184. eCollection 2026.ABSTRACTOBJECTIVE: This narrative review aimed to summarize and critically appraise current evidence on the clinical significance of CTI in cardiovascular disease, stroke, cardiovascular-kidney-metabolic syndrome, cance

S Sheng Yang

Phytosterols in human health: Biochemical mechanisms of action and disease-modulating effects

World J Biol Chem. 2026 Jun 5;17(2):121685. doi: 10.4331/wjbc.v17.i2.121685.ABSTRACTPhytosterols are plant-derived sterols structurally similar to cholesterol and present in vegetable oils, seeds, legumes, and whole grains. Their best-established health effect is lowering circulating low-density lip

D Doha Mohamed

Recurrent Takotsubo Cardiomyopathy Triggered by COVID-19 Infection Complicated by Ventricular Tachycardia Arrest and Cardiogenic Shock: A Case Report

Cureus. 2026 Jun 9;18(6):e110518. doi: 10.7759/cureus.110518. eCollection 2026 Jun.ABSTRACTTakotsubo cardiomyopathy is a transient stress-induced cardiomyopathy typically triggered by emotional or physical stress. Since the emergence of coronavirus disease 2019 (COVID-19), several cardiovascular com

R Roberto R Gonzalez Alvarez

Experience and outcomes of kidney transplantation in a Colombian referral center

Front Nephrol. 2026 May 26;6:1817080. doi: 10.3389/fneph.2026.1817080. eCollection 2026.ABSTRACTBACKGROUND: Kidney transplantation remains the most effective therapy for End-Stage Renal Disease. While global outcomes have improved, data from Latin America are limited.OBJECTIVE: to describe the insti

M Maricel Licht-Ardila

Prognostic Significance of Upstroke Time per Cardiac Cycle in Coronary Artery Disease Patients With Normal Ankle-Brachial Index

Circ Rep. 2026 Apr 15;8(6):1016-1018. doi: 10.1253/circrep.CR-26-0057. eCollection 2026 Jun 10.ABSTRACTBACKGROUND: Whether upstroke time (UT) predicts outcomes after percutaneous coronary intervention (PCI) in patients with normal ankle-brachial index (ABI) remains unclear.METHODS AND RESULTS: In a

J Joh Akama

Impact of Heart Disease and Multimorbidity on Oral Frailty in Japanese Community-Dwelling Older Adults

Circ Rep. 2026 Feb 24;8(6):917-925. doi: 10.1253/circrep.CR-26-0056. eCollection 2026 Jun 10.ABSTRACTBACKGROUND: Oral frailty (OF), defined as a multidimensional decline in oral function, is an early marker of functional vulnerability in older adults. Although frailty is linked to cardiovascular dis

N Nobuhide Ohashi

Factors Associated With Below-the-Ankle Lesions and Their Impact on Clinical Outcomes Following Revascularization in Chronic Limb-Threatening Ischemia

Circ Rep. 2026 Apr 11;8(6):980-987. doi: 10.1253/circrep.CR-26-0063. eCollection 2026 Jun 10.ABSTRACTBACKGROUND: Below-the-ankle (BTA) disease is increasingly prevalent in chronic limb-threatening ischemia (CLTI), particularly in diabetes and end-stage renal disease, but its determinants and prognos

T Tsutomu Doita

Obesity as a Systemic Disease: Metabolic Benefits of Modest Weight Reduction in Specific Health Guidance-Eligible Individuals

No abstractCirc Rep. 2026 Apr 21;8(6):915-916. doi: 10.1253/circrep.CR-26-0058. eCollection 2026 Jun 10.NO ABSTRACTPMID:42273309 | PMC:PMC13249482 | DOI:10.1253/circrep.CR-26-0058

T Tomoya Hara

Characteristics and Outcomes of Multisystemic Inflammation in Patients Clinically Diagnosed With Non-COVID-19-Related Fulminant Myocarditis

Circ Rep. 2026 Apr 25;8(6):970-979. doi: 10.1253/circrep.CR-26-0068. eCollection 2026 Jun 10.ABSTRACTBACKGROUND: In patients with COVID-19-related fulminant myocarditis (COVID-FM), multisystem inflammatory syndrome (MIS) influences clinical outcomes. Multisystemic inflammation (MSI) based on clinica

T Tadatomo Fukushima

Significance of Lipoprotein(a) in Coronary Artery Disease: A Comparative Study of Patients Undergoing Percutaneous Coronary Intervention and Healthy Individuals

Circ Rep. 2026 Mar 31;8(6):943-951. doi: 10.1253/circrep.CR-26-0027. eCollection 2026 Jun 10.ABSTRACTBACKGROUND: Lipoprotein(a) is a risk factor for atherosclerotic cardiovascular disease (ASCVD). However, its distribution based on coronary artery disease (CAD) in the Japanese population remains unc

T Tomoaki Okada

Association of Weight Loss With Improvement in Metabolic Status Among People Eligible for the Specific Health Guidance Program

Circ Rep. 2026 Apr 14;8(6):909-914. doi: 10.1253/circrep.CR-25-0266. eCollection 2026 Jun 10.ABSTRACTBACKGROUND: While international guidelines recommend 5-10% body weight reduction, evidence characterizing the dose-response relationship between specific weight loss amounts and metabolic syndrome (M

M Masachika Nishikawa