J Foot Ankle Res. 2026 Sep;19(3):e70194. doi: 10.1002/jfa2.70194.ABSTRACTINTRODUCTION: Diabetes-related distress (DRD) is exacerbated in people at risk of Diabetes-related Foot Disease (DFD); however, knowledge on this topic is still limited, especially in Primary Health Care (PHC), which focuses on
Heart Fail Rev. 2026 Jul 30;31(1):89. doi: 10.1007/s10741-026-10660-0.ABSTRACTValvular cardiomyopathy has emerged as a key concept linking valvular heart disease (VHD) with myocardial remodeling and the development of heart failure (HF). This state-of-the-art review provides a comprehensive overview
Nat Genet. 2026 Jul 29. doi: 10.1038/s41588-026-02704-w. Online ahead of print.ABSTRACTAutoimmune hypothyroidism (Hashimoto's thyroiditis) is common and has a strong genetic component. Here we performed multi-ancestry genome-wide association meta-analyses encompassing 48,694 Hashimoto's thyroiditis
No abstractNat Rev Mol Cell Biol. 2026 Jul 29. doi: 10.1038/s41580-026-01007-6. Online ahead of print.NO ABSTRACTPMID:42527558 | DOI:10.1038/s41580-026-01007-6
Npj Health Syst. 2025 Apr 26;2(1):13. doi: 10.1038/s44401-025-00017-4.ABSTRACTThe global incidence of chronic diseases is rising, posing substantial social and economic challenges. These conditions necessitate effective long-term self-care, which can be supported by digital interventions using remot
NPJ Biomed Innov. 2026 Jul 29;3(1):44. doi: 10.1038/s44385-026-00101-w.ABSTRACTIn the osteoarthritic joint, activated macrophages release pro-inflammatory factors that promote cartilage degeneration. The CD200:CD200R immune checkpoint pathway is a promising therapeutic target that inhibits classical
Signal Transduct Target Ther. 2026 Jul 29;11(1):309. doi: 10.1038/s41392-026-02915-x.ABSTRACTIntracerebral hemorrhage (ICH) leads to significant neuronal loss and glial scar formation, but the regenerative capacity of the adult brain remains limited. Although small-molecule-induced astrocyte-to-neur
S D Med. 2026 Jun;79(6):271-273.ABSTRACTClostridium innocuum is an anaerobic gram-positive spore-forming bacteria, a commensal member of the human gut microbiome. We encountered a case of bacteremia with this organism as a complication of a foot ulcer in a middle-aged patient with diabetes, end-stag
J Clin Lipidol. 2026 Jul 7:S1933-2874(26)00431-9. doi: 10.1016/j.jacl.2026.07.003. Online ahead of print.ABSTRACTWe compared the predicting risk of cardiovascular EVENTS-atherosclerotic cardiovascular disease (PREVENT-ASCVD) risk equation with the pooled cohort equation (PCE) for estimating statin e
J Clin Lipidol. 2026 Jul 10:S1933-2874(26)00433-2. doi: 10.1016/j.jacl.2026.07.012. Online ahead of print.ABSTRACTBACKGROUND: Familial chylomicronemia syndrome (FCS) is a rare autosomal recessive disorder characterized by severe hypertriglyceridemia (sHTG) due to variants in canonical genes (LPL [li
J Clin Lipidol. 2026 Jul 10:S1933-2874(26)00442-3. doi: 10.1016/j.jacl.2026.07.014. Online ahead of print.ABSTRACTBACKGROUND: Aortic aneurysm and dissection (AA/AD) are life-threatening vascular diseases with high mortality, yet no effective drugs to delay progression. Lipoprotein(a) [Lp(a)] is gene
Heart Lung Circ. 2026 Jul 29:S1443-9506(26)00203-9. doi: 10.1016/j.hlc.2026.01.023. Online ahead of print.ABSTRACTBACKGROUND: Rotational atherectomy has become increasingly common in centres without on-site cardiac surgery to treat heavily calcified coronary artery disease. However, there is limited
No abstractInt J Biol Macromol. 2026 Jul 29:153702. doi: 10.1016/j.ijbiomac.2026.153702. Online ahead of print.NO ABSTRACTPMID:42527172 | DOI:10.1016/j.ijbiomac.2026.153702
J Matern Fetal Neonatal Med. 2026 Dec;39(1):2708471. doi: 10.1080/14767058.2026.2708471. Epub 2026 Jul 29.ABSTRACTOBJECTIVE: To generate the evidence base, using national cohort data, to design a clinical trial evaluating whether cesarean section (CS) or vaginal birth (VB) offers better outcomes for
Zhonghua Er Ke Za Zhi. 2026 Aug 2;64(8):965-968. doi: 10.3760/cma.j.cn112140-20251215-01107.ABSTRACT儿童射血分数保留的心力衰竭（HFpEF）病因谱复杂、表型高度异质，常与先天性心脏病、心肌病、遗传性综合征、肺动脉高压及肥胖代谢异常等因素相关，诊断和治疗均不能简单套用成人经验。近年来，年龄分层的心功能评估、心脏磁共振成像、新型生物标志物及机制导向治疗为儿童HFpEF的识别和干预提供了新思路。现围绕儿童HFpEF的诊断评估、分子病理机制及机制导向治疗进展进行综述，以期为分层诊疗和未来研究提供参考。.
Zhonghua Er Ke Za Zhi. 2026 Aug 2;64(8):949-951. doi: 10.3760/cma.j.cn112140-20260520-00401.ABSTRACT患儿，女，3月龄，因“发育迟缓3个月”就诊深圳市儿童医院风湿免疫科，以生长发育迟缓、面容异常及反复喉鸣为主要临床表现，外周血常规提示白细胞及中性粒细胞减少。基因测序示ZNF699基因第2号外显子c.14-17delGAAA（p.Arg5fsTer14）和第6号外显子c.975-976delCA（p.His325fsTer8）复合杂合变异，分别遗传自其母亲和父亲。诊断为伴有胃肠道、心血管、泌尿生殖系
Zhonghua Er Ke Za Zhi. 2026 Aug 2;64(8):936-940. doi: 10.3760/cma.j.cn112140-20251226-01146.ABSTRACTObjective: To evaluate the efficacy and clinical outcomes of transcatheter closure of intracristal ventricular septal defect (VSD) using an eccentric occluder. Methods: In this case series study, 39 c
Zhonghua Er Ke Za Zhi. 2026 Aug 2;64(8):905-910. doi: 10.3760/cma.j.cn112140-20251119-01039.ABSTRACTObjective: To investigate the risk factors of vascular function damage in children with primary hypertension and establish a risk prediction model. Methods: In this retrospective case-control study, a
Zhonghua Er Ke Za Zhi. 2026 Aug 2;64(8):898-904. doi: 10.3760/cma.j.cn112140-20251214-01102.ABSTRACTObjective: To explore age-adapted left ventricular ejection fraction (LVEF) diagnostic thresholds for heart failure with preserved ejection fraction (HFpEF) in children. Methods: In this multicenter r
J Epidemiol Community Health. 2026 Jul 29:jech-2025-225757. doi: 10.1136/jech-2025-225757. Online ahead of print.ABSTRACTPURPOSE: This study assessed whether China's workday-rescheduling policy is associated with short-term and long-term outcomes in patients with ST-segment elevation myocardial infa
No abstractHeart. 2026 Jul 29:heartjnl-2026-328237. doi: 10.1136/heartjnl-2026-328237. Online ahead of print.NO ABSTRACTPMID:42527112 | DOI:10.1136/heartjnl-2026-328237
BMJ Case Rep. 2026 Jul 29;19(7):e272871. doi: 10.1136/bcr-2026-272871.ABSTRACTMicroscopic polyangiitis (MPA) is an anti-neutrophil cytoplasmic antibodies (ANCA)-associated necrotising small-vessel vasculitis that characteristically involves the kidneys and lungs but may also include cutaneous, muscu
BMJ Case Rep. 2026 Jul 29;19(7):e273715. doi: 10.1136/bcr-2026-273715.ABSTRACTA previously healthy surfer apprentice in his late 30s presented to our emergency department with acute paraplegia and loss of sensation in the lower limbs following sudden back pain during his third surfing lesson. The pa
BMJ Case Rep. 2026 Jul 29;19(7):e274851. doi: 10.1136/bcr-2026-274851.ABSTRACTOrbital venolymphatic malformations (OVLM) are rare congenital vascular anomalies that may cause progressive proptosis, visual loss, facial disfigurement and marked psychosocial burden. Management is challenging especially
