Identification of PGF+ endothelial cells associated with plaque instability in carotid atherosclerosis by scRNA-seq and RNA-seq analysis

Cell Cycle. 2026 Dec;25(1):1-20. doi: 10.1080/15384101.2026.2688663. Epub 2026 Jun 28.ABSTRACTVascular endothelial dysfunction plays a critical role in the development of atherosclerosis; however, the mechanisms by which endothelial cells contribute to plaque instability remain incompletely understo

Y Yi Xiang

Alterations in Abdominal Blood Flows After Drinking Coffee

Pharmacol Res Perspect. 2026 Aug;14(4):e70296. doi: 10.1002/prp2.70296.ABSTRACTCoffee exerts beneficial effects on health, such as suppressing type 2 diabetes, cardiovascular disease, and fatty liver. Coffee also relieves headaches by the caffeine component decreasing blood flow in the cerebral arte

S Soshi Owada

Multi-Center Adversarial Bi-Phase Cross-Attention Network for Right Ventricular Segmentation and Functional Classification in Echocardiography

Echocardiography. 2026 Jul;43(7):e70527. doi: 10.1111/echo.70527.ABSTRACTBACKGROUND: Automated right ventricular (RV) analysis in 2D echocardiography is limited by the morphological complexity of RV segmentation and the domain fragility of single-center deep learning models across ultrasound vendors

B Bozhi Zhang

Perceptions of People From South Asian Backgrounds With Chronic Kidney Disease on Digital Health Interventions: Patient and Public Involvement and Engagement Consultation Focus Group

Health Expect. 2026 Aug;29(4):e70745. doi: 10.1111/hex.70745.ABSTRACTINTRODUCTION: Digital health interventions (DHIs) are increasingly popular as a potential method to address educational and support needs of individuals with long-term conditions, as they are largely accessible to most people, can

C Courtney J Lightfoot

Fractal Complexity of the Circle of Willis Links Circulating Microparticles to Silent Cerebral Small Vessel Disease

Clin Anat. 2026 Jun 27. doi: 10.1002/ca.70155. Online ahead of print.ABSTRACTCerebral small vessel disease (CSVD) is a leading cause of vascular cognitive impairment, yet its earliest stages remain clinically silent and poorly detected. Although white matter hyperintensities (WMHs) are widely used n

Z Zaw Myo Hein

A comprehensive review on chemical structure, quality control, pharmacological effects, and structure-activity relationship of saponins from Zhuzishen ()

J Tradit Chin Med. 2026 Jun;46(3):757-767. doi: 10.19852/j.cnki.jtcm.2026.03.016.ABSTRACTZhuzishen (Rhizoma Panacis Majoris) is the dried rhizome and root of Panax japonicus C.A. Meyer. var major (Burk.) C.Y. Wu et K.M. Feng or Panax japonicus Meyer. Var. bipinnatifidus (Seem.) C.Y. Wu et K.M. Feng,

M Min Zeting

Cheek acupuncture therapy combined with Chinese herbal medicine for female chronic pelvic pain: a retrospective study

J Tradit Chin Med. 2026 Jun;46(3):726-732. doi: 10.19852/j.cnki.jtcm.2026.03.012.ABSTRACTOBJECTIVE: To investigate the effect of cheek acupuncture therapy combined with Chinese herbal medicine on chronic pelvic pain (CPP) in female patients.METHODS: Female patients with CPP treated with cheek acupun

S Song Ying

Clinical characteristics of acupoint sensitization in patients with essential hypertension: a cross-sectional matched case-control study

J Tradit Chin Med. 2026 Jun;46(3):684-694. doi: 10.19852/j.cnki.jtcm.20251030.001.ABSTRACTOBJECTIVE: To observe the characteristics of acupoint sensitization in patients with essential hypertension, analyze the mechanical pain threshold and tenderness threshold of each acupoint, and summarize the cl

G Gong Yu

Evaluation of the anti-apoptotic, anti-platelet aggregation, and pro-angiogenic properties of Naoshuantong capsule in ischemic stroke: insights from network pharmacology and animal experiments

J Tradit Chin Med. 2026 Jun;46(3):629-640. doi: 10.19852/j.cnki.jtcm.20260304.001.ABSTRACTOBJECTIVE: To explore the complex molecular mechanisms of Naoshuantong capsule (, NST), a Traditional Chinese Medicine formula, against ischemic stroke (IS) using network pharmacology and various experimental v

L L I Chuanpeng

Yiqi Huoxue formula relieves heart failure with reduced ejection fraction in calcium/calmodulin-dependent protein kinase Ⅱ delta B isoform and calcium/calmodulin-dependent protein kinase Ⅱ delta C isoform transgenic mice by inhibiting myocardial remodeling and enhancing calcium homeostasis

J Tradit Chin Med. 2026 Jun;46(3):530-543. doi: 10.19852/j.cnki.jtcm.20260214.001.ABSTRACTOBJECTIVE: To confirm the efficacy of Yiqi Huoxue formula (, YQHX) on heart failure with reduced ejection fraction (HFrEF), and elucidate its potential effect on calcium homeostasis.METHODS: Cardiac specific ca

X X U Jianglin

Activation of the nucleus nuclear factor erythroid 2-related factor 2ghrelin/growth hormone secretagogue receptor 1a signaling by Yueju pill confers cardioprotective and antidepressant effects

J Tradit Chin Med. 2026 Jun;46(3):517-529. doi: 10.19852/j.cnki.jtcm.2026.03.001.ABSTRACTOBJECTIVE: To investigate the efficacy and mechanistic foundations of the Traditional Chinese Medicine Yueju pill (YJP, ) for treating the complex comorbidity of heart failure and depression.METHODS: C57BL/6 mal

J Jing Yunjia

Association between perceived stress and metabolic parameters: a systematic review and meta-analysis

Diabetol Metab Syndr. 2026 Jun 27. doi: 10.1186/s13098-026-02220-1. Online ahead of print.ABSTRACTBACKGROUND: Metabolic syndrome (MetS) is a major global public health problem associated with cardiovascular disease, type 2 diabetes mellitus (T2D), and increased mortality. Chronic psychological stres

K Karla Fernanda Garcia-Ravelo

Cardiac organoids in toxicology: from construction strategies and research trends to precision screening applications

Stem Cell Res Ther. 2026 Jun 27. doi: 10.1186/s13287-026-05114-1. Online ahead of print.ABSTRACTCardiovascular diseases (CVDs) are the leading cause of death worldwide, with significant attention focused on the development of therapeutic drugs and research into pathogenic mechanisms. In the real wor

L Liya Qiao

Comparative cardiovascular efficacy of antidiabetic therapies in type 2 diabetes: a systematic review and network meta-analysis of randomized trials

Diabetol Metab Syndr. 2026 Jun 27. doi: 10.1186/s13098-026-02226-9. Online ahead of print.ABSTRACTBACKGROUND: Cardiovascular diseases (CVDs) remain the leading cause of morbidity and mortality among individuals with type 2 diabetes mellitus (T2DM), imposing a substantial burden on healthcare systems

D Donya Mohammadi

Identification of a novel pathogenic variant in MYLK in an Iranian family with non-syndromic familial aortic aneurysm and dissection by whole-exome sequencing and literature review

BMC Med Genomics. 2026 Jun 27. doi: 10.1186/s12920-026-02419-1. Online ahead of print.ABSTRACTBACKGROUND: Non-syndromic familial thoracic aortic aneurysm and dissection (ns-FTAAD) is an inherited disease that follows an autosomal dominant pattern; however, pinpointing the responsible genes is often

H Hamide Jafari

Aging with burden: multimorbidity, depression and quality of life in older adults residing in long-term care facilities in South Africa

BMC Geriatr. 2026 Jun 27. doi: 10.1186/s12877-026-07846-4. Online ahead of print.ABSTRACTBACKGROUND: Population ageing has become an immediate global imperative, with older adults disproportionately afflicted by multimorbidity, a complex interplay of co-existing chronic diseases that erodes health-r

S Shane Naidoo

Longitudinal changes and cumulative exposure of cardiometabolic index predict cardiovascular disease risk in middle-aged and older adults: a national prospective cohort study

BMC Cardiovasc Disord. 2026 Jun 27. doi: 10.1186/s12872-026-06101-3. Online ahead of print.ABSTRACTBACKGROUND: Cardiovascular disease (CVD) remains the leading cause of morbidity and mortality among aging populations. Single-time-point risk assessments may not reflect dynamic cardiometabolic changes

X Xiaoyun Liu

Zinc deficiency in patients with type 2 diabetes increases risk of cardiovascular diseases: Tehran Lipid and Glucose Study

BMC Cardiovasc Disord. 2026 Jun 27. doi: 10.1186/s12872-026-06182-0. Online ahead of print.ABSTRACTBACKGROUND AND AIM: This study aimed to assess the prospective association between zinc (Zn) deficiency and the risk of cardiovascular diseases (CVD), CVD mortality and all-cause mortality in adults wi

Z Zahra Bahadoran

Beyond vasodilation: sotatercept and the remodeling hypothesis in hfpef-associated pulmonary hypertension

Heart Fail Rev. 2026 Jun 28;31(1):76. doi: 10.1007/s10741-026-10652-0.ABSTRACTPulmonary hypertension complicating heart failure with preserved ejection fraction (HFpEF), particularly the combined post- and pre-capillary form (CpcPH), has lacked any mechanism-specific therapy, as repeated trials of p

B Brett W Sperry

Hepatic artery aneurysm rupture into the biliary tract during long-term left ventricular assist device support successfully treated by transcatheter arterial embolization: a case report

J Artif Organs. 2026 Jun 27;29(3):38. doi: 10.1007/s10047-026-01566-7.ABSTRACTBleeding complications remain a major concern in patients supported by long-term left ventricular assist devices (LVADs). Although gastrointestinal bleeding is common, hemobilia due to rupture of a hepatic artery aneurysm

F Fumika Haga

Multiscale Mechanisms that Underlie Intermittent Theta-burst Stimulation in Post-stroke Motor Recovery: From Molecular Signaling to Network Reorganization

Transl Stroke Res. 2026 Jun 28;17(4):71. doi: 10.1007/s12975-026-01467-0.ABSTRACTAlthough intermittent theta-burst stimulation (iTBS) has emerged as a promising time-efficient and non-invasive neuromodulatory strategy in post-stroke motor rehabilitation, its clinical efficacy remains variable across

C Cheng Xie

A potential survival benefit in coronary artery bypass grafting with micro-axial temporary pump recovery in patients with reduced left ventricular ejection fraction

J Artif Organs. 2026 Jun 27;29(3):39. doi: 10.1007/s10047-026-01564-9.ABSTRACTCoronary artery bypass grafting (CABG) with temporary micro-axial ventricular assist device (Impella, Johnson and Johnson, Danvers, MA, USA) for peri-operative recovery has been utilized among patients with reduced left ve

A Anjeli Reyes Macaranas

Diastolic echocardiographic parameters identify pediatric kidney transplant recipients with structural myocardial alterations

Pediatr Nephrol. 2026 Jun 27. doi: 10.1007/s00467-026-07416-1. Online ahead of print.ABSTRACTBACKGROUND: Cardiac complications are among the most common causes of death in patients after pediatric kidney transplantation (KTx), but defined diagnostic procedures identifying young patients at risk are

J Jeannine von der Born

Diffusion of carbon monoxide in the lungs and pulmonary artery pressures in school aged children who were born preterm

CONCLUSION: Low K(CO) was associated with higher SPAP and MPAP and lower FEV(1)/FVC in school-aged children born premature. We speculate early and serial assessments of lung function with K(CO) may identify subjects born preterm at high risk for pulmonary hypertension who would benefit from cardiac

C Christopher Harris