Optimizing early triage for subclinical cardiovascular-kidney-metabolic syndrome: longitudinal associations, incremental value, and clinical utility of nine insulin resistance surrogates

Cardiovasc Diabetol. 2026 Jun 21. doi: 10.1186/s12933-026-03266-1. Online ahead of print.ABSTRACTBACKGROUND: Cardiovascular-kidney-metabolic (CKM) syndrome stage 3 represents a critical, yet highly insidious, window of subclinical target organ damage. We aimed to comprehensively compare nine baselin

Y Yingxiu Huang

Consumption of sugar-sweetened beverages and all-cause mortality and cause-specific mortality: insights from nationwide prospective cohort studies and Global Burden of Disease study 2021

Diabetol Metab Syndr. 2026 Jun 21. doi: 10.1186/s13098-026-02215-y. Online ahead of print.ABSTRACTBACKGROUND: Sugar-sweetened beverages (SSBs) consumption has become an emerging global public health concern. The relationship between SSBs consumption and mortality is not yet fully clarified. This stu

X Xiaolu Tan

Emerging directions in tauopathy research

Alzheimers Dement. 2026 Jun;22(6):e71431. doi: 10.1002/alz.71431.ABSTRACTThe Tau Global Conference 2025, hosted by the Alzheimer's Association, CurePSP, and the Rainwater Charitable Foundation, convened international experts from academia, industry, government, and philanthropy to explore advances a

L Luc Buée

Association of noninvasive liver fibrosis scores with severity and outcomes among individuals with cardiovascular-kidney-metabolic syndrome: evidence from the NHANES 2005-2018

BMC Cardiovasc Disord. 2026 Jun 22. doi: 10.1186/s12872-026-06148-2. Online ahead of print.ABSTRACTBACKGROUND: This study aimed to investigate the associations of multiple noninvasive liver fibrosis scores with cardiovascular-kidney-metabolic (CKM) syndrome severity and clinical outcomes.METHODS: Th

Y Yue Gao

LAD/BSA and NT-proBNP as predictors of cardiovascular death in pediatric left ventricular non-compaction: a multicenter longitudinal cohort study

Pediatr Res. 2026 Jun 22. doi: 10.1038/s41390-026-05198-8. Online ahead of print.ABSTRACTBACKGROUND: Pediatric left ventricular non-compaction (LVNC) has a heterogeneous prognosis, with cardiovascular death as a major threat. This study explored predictive markers and aimed to construct a simplified

J Jinsong Jiang

Cumulative visceral fat burden and progression to advanced cardiovascular kidney metabolic syndrome in Chinese middle-aged and older adults

Sci Rep. 2026 Jun 21. doi: 10.1038/s41598-026-58351-y. Online ahead of print.ABSTRACTVisceral adiposity is increasingly recognized as a key contributor to cardiovascular-kidney-metabolic (CKM) syndrome, yet longitudinal evidence regarding both baseline visceral fat burden and cumulative metabolic ex

Z Zihan Fang

2026 Focus Update of the 2021 Korean Society of Myocardial Infarction Expert Consensus Document on Revascularization for Acute Coronary Syndromes

Korean Circ J. 2026 May 7. doi: 10.4070/kcj.2026.0005. Online ahead of print.ABSTRACTThis focused update from the Korean Society of Myocardial Infarction provides consensus recommendations for revascularization in acute coronary syndrome (ACS), integrating major trial evidence since 2021 with Korean

S Seung Hun Lee

Primary Myelofibrosis (PMF)-The German ONKOPEDIA Guideline 2025

Int J Cancer. 2026 Jun 21. doi: 10.1002/ijc.70596. Online ahead of print.ABSTRACTMyelofibrosis (MF) is a rare, clonal disorder of pluripotent hematopoietic stem and progenitor cells. It is characterized by abnormal proliferation of hematopoiesis, associated with pathologically increased fibrosis in

M Martin Griesshammer

Association between hair loss and cardiometabolic diseases in Chinese adults: a cross-sectional analysis in Tianning Cohort

J Epidemiol. 2026 Jun 20. doi: 10.2188/jea.JE20250596. Online ahead of print.ABSTRACTOBJECTIVES: The rising prevalence and earlier onset of hair loss have highlighted its associations with cardiovascular risk factors (hypertension, diabetes, dyslipidemia) and comorbidities among adults. This cross-s

H Hao Peng

Advances of 18 kDa translocator protein (TSPO) in cardiovascular diseases: molecular imaging diagnosis and targeted therapy perspectives

Zhonghua Xin Xue Guan Bing Za Zhi. 2026 Jun 24;54(6):717-723. doi: 10.3760/cma.j.cn112148-20251126-00826.ABSTRACT18 kDa转位蛋白（TSPO）是定位于线粒体外膜的关键蛋白，参与调控胆固醇转运、活性氧生成及线粒体通透性转换孔开放等核心过程。TSPO在正常心脏组织中呈基础表达，在病理状态下表达上调，并对心脏功能具有双重影响。鉴于其重要功能，TSPO已成为心血管疾病分子影像与靶向治疗的研究热点。该文系统论述了TSPO通过线粒体途径在动脉粥样硬化、心肌梗死与再灌注损伤、心律失常等多种心血

S S Y Su

PRDX1 attenuates hypertensive endothelial dysfunction by inhibiting mTOR/p70S6K signaling

Zhonghua Xin Xue Guan Bing Za Zhi. 2026 Jun 24;54(6):671-684. doi: 10.3760/cma.j.cn112148-20250918-00662.ABSTRACTObjective: To explore the role and molecular mechanism of peroxiredoxin 1 (PRDX1) in hypertension-induced endothelial dysfunction. Methods: (1) Bioinformatics analysis: A total of 40 C57B

Y Y Liang

Incremental value of CMR for the 2025 appropriate use criteria of ICD implantation in sudden cardiac death risk stratification of dilated cardiomyopathy

Zhonghua Xin Xue Guan Bing Za Zhi. 2026 Jun 24;54(6):661-670. doi: 10.3760/cma.j.cn112148-20251215-00875.ABSTRACTObjective: To evaluate the predictive value of the 2025 appropriate use criteria (AUV) for implantable cardioverter defibrillators (ICD) jointly issued by the American College of Cardiolo

D D Zhou

Impact of the mismatch between respiratory event frequency and hypoxic burden on cardiovascular outcomes in patients with obstructive sleep apnea

Zhonghua Xin Xue Guan Bing Za Zhi. 2026 Jun 24;54(6):654-660. doi: 10.3760/cma.j.cn112148-20260430-00279.ABSTRACTObjective: To investigate the impact of the mismatch between respiratory event frequency and hypoxic burden on cardiovascular outcomes in patients with obstructive sleep apnea (OSA). Meth

J J Q Du

Clinical characteristics, antithrombotic therapy, and prognosis of new-onset atrial fibrillation in the acute phase of ST-segment elevation myocardial infarction

Zhonghua Xin Xue Guan Bing Za Zhi. 2026 Jun 24;54(6):646-653. doi: 10.3760/cma.j.cn112148-20250707-00494.ABSTRACTObjective: To investigate the clinical characteristics and antithrombotic treatment strategies in patients with acute ST-segment elevation myocardial infarction (STEMI) who develop new-on

H H B Zhai

Efficacy and safety of ticagrelor versus clopidogrel after percutaneous coronary intervention in patients with acute coronary syndrome without standard modifiable cardiovascular risk factors

Zhonghua Xin Xue Guan Bing Za Zhi. 2026 Jun 24;54(6):629-636. doi: 10.3760/cma.j.cn112148-20260204-00080.ABSTRACTObjective: To evaluate the efficacy and safety of ticagrelor versus clopidogrel in real-world patients with acute coronary syndrome (ACS) without standard modifiable cardiovascular risk f

K K Na

Microvascular dysfunction and neurovascular signalling impairment in diabetic silent myocardial ischemia

Microvasc Res. 2026 Jun 21:104983. doi: 10.1016/j.mvr.2026.104983. Online ahead of print.ABSTRACTDiabetic silent myocardial ischemia (DSMI) represents a clinically underappreciated yet life-threatening cardiovascular complication in which impaired myocardial perfusion occurs without recognisable sym

H Harish Karuppiah Rajasekaran

Therapeutic potential of ELABELA in alleviating hereditary hypertrophic cardiomyopathy

J Adv Res. 2026 Jun 21:S2090-1232(26)00509-6. doi: 10.1016/j.jare.2026.06.027. Online ahead of print.ABSTRACTINTRODUCTION: Hereditary hypertrophic cardiomyopathy (HCM) is a common genetic heart disease associated with heart failure and sudden cardiac death. Current therapies are limited, and the myo

C Chao Ye

Fractional Flow Reserve-Guided Versus Coronary Angiography Alone for Guiding Coronary Artery Bypass Grafting: A Meta-Analysis of Randomized Trials

Am J Cardiol. 2026 Jun 21:S0002-9149(26)00419-4. doi: 10.1016/j.amjcard.2026.06.020. Online ahead of print.ABSTRACTCoronary artery bypass grafting (CABG) is traditionally guided by coronary angiography, although angiographic severity may not accurately reflect the physiological significance of coron

O Omar Fayez Abbas

Cardiovascular and limb outcomes with SGLT2 inhibitors in patients with diabetes following peripheral endovascular therapy

J Cardiol. 2026 Jun 21:S0914-5087(26)00125-5. doi: 10.1016/j.jjcc.2026.06.012. Online ahead of print.ABSTRACTBACKGROUND: Although sodium-glucose cotransporter-2 inhibitors (SGLT2i) are recommended for patients with diabetes mellitus (DM) and peripheral artery disease (PAD), their effects on limb-rel

Y Yusuke Tomoi

Contrastive Machine Learning to Quantify Hypertensive Multiorgan Damage and Identify New Disease Phenotypes: A Multinational Multimodal Study

Circulation. 2026 Jun 21. doi: 10.1161/CIRCULATIONAHA.125.077394. Online ahead of print.ABSTRACTBACKGROUND: Hypertension induces structural and functional damage in multiple organs. Evidence of subclinical damage increases risk of vascular events and death but can be difficult to identify in the cli

M Mohanad Alkhodari

Relative contributions of climate factors and air pollution to childhood allergic diseases in Chongqing, China

BMC Public Health. 2026 Jun 22. doi: 10.1186/s12889-026-28203-5. Online ahead of print.ABSTRACTBACKGROUND: Climate and air pollution are associated with pediatric allergic diseases; however, their relative impacts remain poorly understood, particularly in subtropical climates. This study quantified

R Rong Sun

Mitochondria-associated endoplasmic reticulum membrane (MAM): roles in innate immunity dysregulation

Cell Commun Signal. 2026 Jun 22. doi: 10.1186/s12964-026-03013-9. Online ahead of print.ABSTRACTMitochondria-associated endoplasmic reticulum membrane (MAM), which serves as a signaling hub for interactions between the endoplasmic reticulum (ER) and mitochondria, dynamically coordinates innate immun

Q Qingqi Zhang

Consistency Matters: Clopidogrel Monotherapy as Long-term Secondary Prevention Following Percutaneous Coronary Intervention

No abstractKorean Circ J. 2026 Apr 28. doi: 10.4070/kcj.2026.0092. Online ahead of print.NO ABSTRACTPMID:42324227 | DOI:10.4070/kcj.2026.0092

W Woong Gil Choi

Mapping the Cell-Cell Interactions in Cardiovascular Diseases: A Single-Cell Atlas Perspective

Korean Circ J. 2026 Apr 14. doi: 10.4070/kcj.2026.0007. Online ahead of print.ABSTRACTCell-cell interactions play a critical role in maintaining cardiovascular homeostasis by coordinating communication among cardiomyocytes, endothelial cells, fibroblasts, smooth muscle cells, and immune cells. In ca

S Seungyoon Song