Strategies for Optimizing Heart Failure Care in the Older Adult: A Scientific Statement From the American Heart Association

Circulation. 2026 Jun 18. doi: 10.1161/CIR.0000000000001437. Online ahead of print.ABSTRACTHeart failure prevalence is increasing and has a disproportionate burden on older adults. Older adults, however, may encounter unique challenges in accessing and navigating comprehensive disease-modifying, gui

S Sabra C Lewsey

Elevated atherogenic index of plasma is associated with severe acute kidney injury in critically ill patients with cardiovascular disease - a MIMIC-IV analysis with external validation in the eICU-CRD database

Ren Fail. 2026 Dec;48(1):2685354. doi: 10.1080/0886022X.2026.2685354. Epub 2026 Jun 18.ABSTRACTThe atherogenic index of plasma (AIP) is a lipid-based marker of cardiovascular risk, yet its prognostic value for severe acute kidney injury (AKI) in critically ill patients with cardiovascular disease (C

P Peng Liu

Coronary artery calcium and multiparametric cardiovascular risk assessment in non-dialysis chronic kidney disease

Biomol Biomed. 2026 Jun 18. doi: 10.17305/bb.2026.14105. Online ahead of print.ABSTRACTCardiovascular disease is a leading cause of mortality in chronic kidney disease (CKD), but whether impaired renal function independently increases coronary artery calcium (CAC) burden in patients with comparable

I Ivana Đuran

Endothelial Nucleoporin93 (Nup93) Maintains Vascular Homeostasis via Sun1-Dependent Regulation of RhoA/ROCK Activity

Arterioscler Thromb Vasc Biol. 2026 Jun 18. doi: 10.1161/ATVBAHA.126.324964. Online ahead of print.ABSTRACTBACKGROUND: As the innermost lining of blood vessels, endothelial cells regulate barrier function, maintain vascular tone, and limit inflammation for vessel health. Involved in various fundamen

T Tung D Nguyen

miR-146a Deficiency Ablates β-Aminopropionitrile-Induced Thoracic Aortic Aneurysmal Rupture in Mice

No abstractArterioscler Thromb Vasc Biol. 2026 Jun 18. doi: 10.1161/ATVBAHA.126.324360. Online ahead of print.NO ABSTRACTPMID:42312359 | DOI:10.1161/ATVBAHA.126.324360

N Nithya Ramesh

The role of metabolic health in neurostructural and cognitive alterations in bipolar disorders

Psychol Med. 2026 Jun 18;56:e197. doi: 10.1017/S0033291726104905.ABSTRACTBACKGROUND: Bipolar disorders (BD) rank among the most disabling conditions, affecting millions worldwide. Cognitive impairment in BD is linked with brain changes and worse functional outcomes. Obesity and metabolic syndrome (M

M Maya Selitser

Correction to: Sex difference in cardiovascular risk in patients with chronic kidney disease: pooled analysis of four cohort studies

No abstractNephrol Dial Transplant. 2026 Jun 18:gfag125. doi: 10.1093/ndt/gfag125. Online ahead of print.NO ABSTRACTPMID:42312321 | DOI:10.1093/ndt/gfag125

Cardiovascular-kidney-metabolic (CKM) syndrome

Aust Prescr. 2026 Jun;49(3):79-83. doi: 10.18773/austprescr.2026.026.ABSTRACTCardiovascular-kidney-metabolic (CKM) syndrome recognises the connection between metabolic conditions (particularly obesity, diabetes and metabolic dysfunction-associated fatty liver disease), chronic kidney disease and car

K Karen M Dwyer

Associations of clinical obesity with arterial stiffness and cerebral small vessel disease: a population-based study

Front Endocrinol (Lausanne). 2026 Jun 2;17:1793231. doi: 10.3389/fendo.2026.1793231. eCollection 2026.ABSTRACTOBJECTIVES: Based on the comprehensive indicator of clinical obesity, this study investigates its association with arterial stiffness and cerebral small vessel disease (cSVD).METHODS: This c

M Mengmeng Bai

Kidney-Targeted Nanoparticle Delivery of Formoterol Mitigates Diabetic Kidney Disease without Adverse Cardiac Effects

ACS Pharmacol Transl Sci. 2026 May 1;9(6):1426-1438. doi: 10.1021/acsptsci.6c00009. eCollection 2026 Jun 12.ABSTRACTMitochondrial dysfunction plays a critical role in the progression of diabetic kidney disease (DKD). Previous research indicates that the FDA-approved β2-adrenergic receptor agonist an

E Ernest L Vallorz

Therapeutic Strategies for Hyperuricemia: From Small-Molecule Inhibitors to RNA Therapeutics

ACS Pharmacol Transl Sci. 2026 May 22;9(6):1318-1330. doi: 10.1021/acsptsci.6c00134. eCollection 2026 Jun 12.ABSTRACTHyperuricemia is a common metabolic disorder caused by purine metabolism dysregulation or impaired uric acid excretion, and it is closely associated with gout, chronic kidney disease,

X Xi Yu

Quantitative Measurement of Extracellular Vesicle-Sized Particles in Blood Plasma by Laser Diffraction Without an Extraction Process: A Proof-of-Concept Study in Atrial Fibrillation

J Arrhythm. 2026 Jun 16;42(3):e70379. doi: 10.1002/joa3.70379. eCollection 2026 Jun.ABSTRACTBACKGROUND: Extracellular vesicles (EVs) circulate in blood and may serve as disease biomarkers. However, in atrial fibrillation (AF), reliable circulating biomarkers remain limited. Conventional quantificati

G Giichi Nitta

Design and implementation of interventions to improve sexual health of women with endometriosis: A mixed-methods study protocol with an interventional design

Int J Reprod Biomed. 2026 Jun 2;24(4):297-314. doi: 10.18502/ijrm.v24i4.21170. eCollection 2026 Apr.ABSTRACTBACKGROUND: Endometriosis has potential negative effects on the fertility, mental, and sexual health of women. Since the conducted studies have not comprehensively addressed the needs and stra

T Tahmineh Farajkhoda

SPISE Index (Single-Point Insulin Sensitivity Estimator): A Long-Term Predictor of Recurrence in Elderly Patients with Atrial Fibrillation After Radiofrequency Ablation

Clin Interv Aging. 2026 Jun 12;21:608687. doi: 10.2147/CIA.S608687. eCollection 2026.ABSTRACTBACKGROUND: Insulin resistance (IR) plays a significant role in the onset and progression of atrial fibrillation (AF). The single-point insulin sensitivity estimator (SPISE) index is a novel marker for asses

Z Zhen Wang

Anaerobe-associated microbial shifts at infection onset in diabetes-related foot ulcers revealed by longitudinal metagenomics

Front Cell Infect Microbiol. 2026 Jun 2;16:1812721. doi: 10.3389/fcimb.2026.1812721. eCollection 2026.ABSTRACTINTRODUCTION: Diabetes-related foot infections (DRFIs) are a major cause of hospitalisation and carry a significantly increased risk of lower extremity amputation. To date there is a lack of

M Michael Radzieta

Global, regional, and national burdens of human papillomavirus-associated cervical cancer attributable to sexually acquired human papillomavirus infections among individuals aged 10-54 years from 1990 to 2021: findings from the Global Burden of Disease study 2021

Sex Med. 2026 Jun 16;14(4):qfag045. doi: 10.1093/sexmed/qfag045. eCollection 2026 Aug.ABSTRACTBACKGROUND: Human papillomavirus (HPV) infections that cause cervical cancer (CC) are transmitted through sexual contact. Certain sexual behaviors influence the risk of HPV acquisition and transmission.AIM:

P Pengkhun Nov

Loneliness without an epidemic: gendered pathways, health consequences, and intervention gaps among men in the United States

Front Public Health. 2026 Jun 2;14:1817065. doi: 10.3389/fpubh.2026.1817065. eCollection 2026.ABSTRACTINTRODUCTION: Male loneliness has become one of the most significant public health concerns in recent years, also referred to as an "epidemic." Research demonstrates that men are at greater risk tha

D Dalia Chowdhury

Heterogeneity of eHealth literacy and treatment burden in older adults with heart failure: a multidimensional latent profile analysis

Front Public Health. 2026 Jun 2;14:1822855. doi: 10.3389/fpubh.2026.1822855. eCollection 2026.ABSTRACTBACKGROUND: Heart failure (HF) management imposes a substantial multidimensional treatment burden (BoT) on older adults. While digital health interventions offer potential solutions, their success h

X Xiaoxia Wu

AI-driven cardiovascular risk prediction in patients with diabetes: bridging algorithmic innovation to equitable clinical application

Front Med (Lausanne). 2026 Jun 2;13:1831220. doi: 10.3389/fmed.2026.1831220. eCollection 2026.ABSTRACTMachine learning models hold promise to revolutionize cardiovascular disease (CVD) prediction in patients with type 2 diabetes, with algorithms such as neural networks demonstrating superior discrim

H Hongxuan Li

Social isolation and loneliness: an integration framework for medical education

Front Med (Lausanne). 2026 Jun 2;13:1813649. doi: 10.3389/fmed.2026.1813649. eCollection 2026.ABSTRACTLoneliness and social isolation are increasingly recognized as critical public health issues, linked to adverse outcomes such as cardiovascular disease, cognitive decline, depression, and increased

J Jerlinda G C Ross

Controlled hyperventilation using a new ventilation navigator software: a feasibility study to provoke hypocapnia and respiratory alkalosis: A proposal for coronary artery vasoreactivity assessment

Eur Heart J Imaging Methods Pract. 2026 Apr 17;4(1):qyag070. doi: 10.1093/ehjimp/qyag070. eCollection 2026 Jan.ABSTRACTAIMS: To develop a ventilation navigator to provide controlled hyperventilation and to assess the feasibility to monitor hypocapnia and respiratory alkalosis in healthy subjects.MET

A Attila Kardos

Risk prediction models for postoperative atrial fibrillation in patients with lung cancer: a systematic review and meta-analysis

Front Cardiovasc Med. 2026 Jun 2;13:1779009. doi: 10.3389/fcvm.2026.1779009. eCollection 2026.ABSTRACTBACKGROUND: Postoperative atrial fibrillation (POAF) is a common and clinically significant complication following lung cancer surgery, associated with increased morbidity and mortality. Although nu

F Fei Yang

Knowledge graph visualization and retrospective analysis of genetic research on pediatric cardiomyopathy (2000-2024)

Front Cardiovasc Med. 2026 Jun 2;13:1780649. doi: 10.3389/fcvm.2026.1780649. eCollection 2026.ABSTRACTBACKGROUND: Pediatric cardiomyopathy is a leading cause of heart failure and sudden cardiac death in children, posing a severe threat to their health and lives while imposing a heavy burden on famil

X Xiaohua Han

Circulating biomarkers improve prediction of postoperative outcome after aortic valve surgery

Front Cardiovasc Med. 2026 Jun 2;13:1813821. doi: 10.3389/fcvm.2026.1813821. eCollection 2026.ABSTRACTBACKGROUND: Predicting adverse outcomes following aortic valve surgery remains challenging. This study aimed to investigate the association between preoperative circulating biomarkers and postoperat

T Till Joscha Demal