J Am Board Fam Med. 2026 Aug;39(1):165782. doi: 10.3122/jabfm.2025.250473R1.ABSTRACTA commonly used GLP-1 agonist, semaglutide, reduces the risk of adverse cardiovascular outcomes in non-diabetic individuals with obesity and pre-existing cardiovascular disease.PMID:42624784 | DOI:10.3122/jabfm.2025.
Birth Defects Res. 2026 Aug;118(8):e70107. doi: 10.1002/bdr2.70107.ABSTRACTBACKGROUND: The preterm birth rate among infants with trisomy 21 is more than twice the rate among the general population. Maternal hypertension and diabetes are established risk factors for preterm birth in the general popul
J Clin Lipidol. 2026 Aug 7:S1933-2874(26)00477-0. doi: 10.1016/j.jacl.2026.07.040. Online ahead of print.ABSTRACTBACKGROUND: Despite achieving target low-density lipoprotein cholesterol (LDL-C) levels, patients with ultrahigh-risk atherosclerotic cardiovascular disease (ASCVD) continue to experience
J Clin Lipidol. 2026 Aug 7:S1933-2874(26)00479-4. doi: 10.1016/j.jacl.2026.08.003. Online ahead of print.ABSTRACTBACKGROUND: Current guidelines recommend 1 measurement of lipoprotein(a) [Lp(a)] in lifetime based on presumed genetically-determined stability. Emerging evidence suggests intraindividual
Nutr Metab Cardiovasc Dis. 2026 Aug 5:104955. doi: 10.1016/j.numecd.2026.104955. Online ahead of print.ABSTRACTBACKGROUND AND AIM: Cardiovascular-kidney-metabolic (CKM) syndrome confers elevated mortality risk, but whether dietary ketogenic ratio (KDR) is associated with mortality in this population
J Cardiothorac Vasc Anesth. 2026 Jul 29:S1053-0770(26)00639-7. doi: 10.1053/j.jvca.2026.07.049. Online ahead of print.ABSTRACTPatients undergoing coronary artery bypass grafting (CABG) with cardiopulmonary bypass (CPB) are exposed to substantial perioperative stress, inflammation, and perfusion vuln
BMJ Case Rep. 2026 Aug 20;19(8):e274410. doi: 10.1136/bcr-2026-274410.ABSTRACTZebra bodies-electron-dense lamellar lysosomal inclusions-are the renal hallmark of Fabry disease, caused by deficient α-galactosidase A (GLA) activity. However, several pharmacological agents with cationic amphiphilic pro
BMJ Case Rep. 2026 Aug 20;19(8):e268322. doi: 10.1136/bcr-2025-268322.ABSTRACTAneurysms and pseudoaneurysms predominantly affect the high-pressure arterial system; venous manifestations are exceedingly rare. While the internal jugular vein is the most common cervical site-typically following cathete
BMJ Case Rep. 2026 Aug 20;19(8):e271517. doi: 10.1136/bcr-2025-271517.ABSTRACTPacemaker lead perforation is a recognised cause of iatrogenic pericardial effusion and may progress to life-threatening cardiac tamponade. Point-of-care ultrasound (POCUS) is essential for rapid bedside evaluation, yet th
BMJ Case Rep. 2026 Aug 20;19(8):e274658. doi: 10.1136/bcr-2026-274658.ABSTRACTAnti-neutrophil cytoplasmic antibody-associated vasculitis (AAV) presenting with predominant gastrointestinal (GI) symptoms in the absence of overt respiratory or renal involvement is rare. We present a young man with recu
BMJ Open Ophthalmol. 2026 Aug 20;11(3):e002787. doi: 10.1136/bmjophth-2026-002787.ABSTRACTAIMS: To establish consensus-based guidance on optimising anti-vascular endothelial growth factor (VEGF) and corticosteroid use in centre-involving diabetic macular oedema (CI-DMO).METHODS: A two-round modified
Open Heart. 2026 Aug 20;13(2):e004325. doi: 10.1136/openhrt-2026-004325.ABSTRACTBACKGROUND: NT-proBNP is a key biomarker in heart failure (HF). Patients with markedly elevated levels are at high risk of adverse outcomes but experience delays in specialist care. Evidence on the impact of an automated
Open Heart. 2026 Aug 20;13(2):e003960. doi: 10.1136/openhrt-2025-003960.ABSTRACTOBJECTIVE: This study aimed to evaluate the safety and efficacy of transapical epicardial temporary pacemaker lead implantation compared with the conventional transvenous approach in patients undergoing transapical trans
BMJ Open. 2026 Aug 19;16(8):e119551. doi: 10.1136/bmjopen-2026-119551.ABSTRACTINTRODUCTION: Fewer than half of patients receive evidence-based upper limb rehabilitation after stroke. Implementation science interventions may improve use of guidelines by clinicians; however, it is not yet known whethe
BMJ Open. 2026 Aug 20;16(8):e122003. doi: 10.1136/bmjopen-2026-122003.ABSTRACTBACKGROUND: Cardiovascular disease risk accelerates in women after the menopausal transition, coinciding with the cessation of endogenous oestrogen production. The accompanying decline in vascular function is considered a
BMJ Open. 2026 Aug 19;16(8):e120795. doi: 10.1136/bmjopen-2026-120795.ABSTRACTOBJECTIVE: Potentially inappropriate prescribing (PIP) in the elderly is associated with adverse outcomes and increased healthcare use. We aimed to estimate its prevalence and pattern among the elderly population of Iran u
Methods Enzymol. 2026;733:407-431. doi: 10.1016/bs.mie.2026.06.021. Epub 2026 Jul 2.ABSTRACTIschemic stroke induced cerebral edema is a devastating complication which leads to excessive swelling, increased intracranial pressure (ICP) and rapid neurological deterioration. The mortality rate of post-s
Kidney Int. 2026 Sep;110(3):533-535. doi: 10.1016/j.kint.2026.06.025.ABSTRACTMoonen et al. evaluated the adverse effects of unilateral ischemia on kidney structure and function and how these effects were modulated by the timing of contralateral nephrectomy. In both rat and mouse, the initial postisc
Kidney Int. 2026 Sep;110(3):529-532. doi: 10.1016/j.kint.2026.06.018.ABSTRACTDespite decades of investigation, effective therapies for medial arterial calcification in chronic kidney disease remain lacking. Emerging therapeutic targets increasingly extend beyond systemic drivers of calcification and
Kidney Int. 2026 Sep;110(3):522-525. doi: 10.1016/j.kint.2026.06.020.ABSTRACTWang et al. showcase a green mamba-derived compound, MQ232, which interferes with cyst growth in a mouse model of autosomal dominant polycystic kidney disease, similar to the only approved drug for autosomal dominant polycy
BMJ. 2026 Aug 20;394:e100363. doi: 10.1136/bmj-2026-100363.ABSTRACTOBJECTIVE: To determine whether an elevated head position (30-40°) improves functional outcomes compared with a flat head position (0-10°) in patients with acute ischaemic stroke caused by anterior circulation large vessel occlusion
No abstractClin Infect Dis. 2026 Aug 21:ciag510. doi: 10.1093/cid/ciag510. Online ahead of print.NO ABSTRACTPMID:42624497 | DOI:10.1093/cid/ciag510
Adv Nutr. 2026 Aug 20:100725. doi: 10.1016/j.advnut.2026.100725. Online ahead of print.ABSTRACTMonounsaturated fatty acids (MUFAs) are dietary fats characterized by a single unsaturated carbon bond. Commonly found in olive oil, avocados, and nuts, MUFAs play a vital role in human health. In a previo
Int J Biochem Cell Biol. 2026 Aug 20:107016. doi: 10.1016/j.biocel.2026.107016. Online ahead of print.ABSTRACTBACKGROUND: Vascular calcification is a major cardiovascular risk factor in chronic kidney disease (CKD), driven by vascular smooth muscle cell (VSMC) osteogenic differentiation. Latent tran
