NDRG2 Drives DRP1 Phosphorylation to Promote the Progression of Pulmonary Hypertension

Front Biosci (Landmark Ed). 2026 Apr 14;31(4):48054. doi: 10.31083/FBL48054.ABSTRACTBACKGROUND: Pulmonary hypertension (PH) is a progressive disease characterized by obstructive pulmonary vascular remodeling, for which no curative therapies effectively reverse disease progression. This study investi

J Jiayong Luo

Ameliorative Effect of Luteolin on H2O2-Induced Mitophagy and Apoptosis in Cardiomyocytes Through Modulation of the AMPK/mTOR Pathway

Front Biosci (Landmark Ed). 2026 Apr 20;31(4):50047. doi: 10.31083/FBL50047.ABSTRACTBACKGROUND: Luteolin, a natural flavonoid, is an active ingredient in traditional herbs used to treat cardiovascular diseases. However, little is known about the effects of luteolin on oxidative damage in cardiomyocy

Z Zhipeng Yang

Potential Application of HIF-PH Inhibitors to Treat Kidney Diseases

Front Biosci (Landmark Ed). 2026 Apr 21;31(4):47718. doi: 10.31083/FBL47718.ABSTRACTHypoxia-inducible factor prolyl hydroxylase (HIF-PH) inhibitors have recently been approved for clinical use in the treatment of renal anemia. HIF-PH inhibitors were developed following studies investigating the role

Y Yuichiro Izumi

ApoA-I Dissociated From Human HDL Retains its Acceptor Properties in ABCA1-mediated Cholesterol Efflux From RAW 264.7 Macrophages in Coronary Artery Disease

Front Biosci (Landmark Ed). 2026 Apr 23;31(4):50403. doi: 10.31083/FBL50403.ABSTRACTBACKGROUND: The significance of cholesterol efflux as a predictor of coronary artery disease (CAD) remains controversial. The intracellular cholesterol export via the ABCA1 transporter involves the acceptance of chol

V Veronika B Baserova

Comparative Effectiveness of High-Dose and Standard-Dose Influenza Vaccines for Hospitalisation and Mortality in Adults Aged 65 and Older: An Updated Systematic Review and Meta-Analysis

Rev Med Virol. 2026 May;36(3):e70158. doi: 10.1002/rmv.70158.ABSTRACTThis updated systematic review and meta-analysis evaluated the relative vaccine effectiveness (rVE) of high-dose inactivated influenza vaccine (HD-IV) versus standard-dose (SD-IV) in adults ≥ 65 years for key clinical outcomes, inc

B Bilal Wazir Khan

Integration of Single-Cell and Spatial Transcriptomics With Experimental Validation Uncovers Macrophage Diversity and Spatial Landscape in Carotid Atherosclerosis

IUBMB Life. 2026 May;78(5):e70105. doi: 10.1002/iub.70105.ABSTRACTThe core pathogenesis of carotid atherosclerosis (CAS) lies in the rupture of vulnerable plaques, with macrophages (MC) playing a critical role in plaque progression and destabilization. However, the functional characteristics of MC s

R Rongxing Qin

Efficacy and Neurophysiological Mechanisms of 10 Hz Repetitive Transcranial Magnetic Stimulation for Post-Stroke Dysphagia: A Randomized Controlled Trial

Rev Neurol. 2026 Apr 22;81(4):49912. doi: 10.31083/RN49912.ABSTRACTBACKGROUND: Post-stroke dysphagia (PSD) is a common and serious complication, yet conventional rehabilitation therapies have limited efficacy. Repetitive transcranial magnetic stimulation (rTMS) is a promising treatment, but its opti

B Bangqiang Hou

Impact of Smoking Cessation Attempts on Outcomes in Metabolic Dysfunction-Associated Steatotic Liver Disease: A Large Propensity Score-Matched Cohort Study

Can J Gastroenterol Hepatol. 2026;2026(1):e5902236. doi: 10.1155/cjgh/5902236.ABSTRACTBACKGROUND AND AIMS: Metabolic dysfunction-associated steatotic liver disease (MASLD) is highly prevalent, and smoking is associated with greater disease severity. We investigated whether documented smoking cessati

M Mohammad Alabbas

Paraoxonase 2 as a target for aging-related diseases

Korean J Physiol Pharmacol. 2026 Apr 29. doi: 10.4196/kjpp.25.354. Online ahead of print.ABSTRACTParaoxonase 2 (PON2) is an enzyme exhibiting both lactonase and esterase activities, widely distributed across various tissues and localized within cellular mitochondria. It plays a vital role in innate

H Hyeong Hwan Kim

FPS-ZM1 Exerts Neuroprotection in Cardiac-Arrest Mice through Inhibiting Oxidative Stress and Pyroptosis via the HMGB1/RAGE Axis

J Integr Neurosci. 2026 Apr 17;25(4):50023. doi: 10.31083/JIN50023.ABSTRACTBACKGROUND: Cardiac arrest (CA) is a widespread public health problem with high mortality, severe neurological sequelae, and limited pharmacological therapies. We investigated the neuroprotective effect of a novel drug, FPS-Z

Y Ying Zhu

The Role of Artificial Intelligence in Diagnosing Acute Ischemic Stroke Using Diffusion MRI: A Multicenter External Validation Study

J Integr Neurosci. 2026 Apr 21;25(4):48811. doi: 10.31083/JIN48811.ABSTRACTBACKGROUND: Acute ischemic stroke is a time-sensitive medical emergency requiring rapid and accurate diagnosis to improve patient outcomes. While Diffusion-Weighted Imaging (DWI) on magnetic resonance imaging (MRI) is highly

B Beyza Nur Kuzan

Regional Associations Between Ocular Vascular Parameters and Enlarged Perivascular Spaces in the Basal Ganglia and Centrum Semiovale

J Integr Neurosci. 2026 Apr 22;25(4):49070. doi: 10.31083/JIN49070.ABSTRACTBACKGROUND: Enlarged perivascular spaces (EPVS) represent a hallmark imaging feature of cerebral small vessel disease. The ocular vasculature is an anatomical extension of cerebral vessels, constituting part of the microvascu

N Nuo Ma

Mortality in Relation to Brachial Versus Central Ambulatory Blood Pressure

Hypertension. 2026 Apr 29. doi: 10.1161/HYPERTENSIONAHA.126.26778. Online ahead of print.ABSTRACTBACKGROUND: Whether central systolic blood pressure (cSBP) compared with brachial systolic blood pressure (bSBP) improves risk stratification remains debated. This study investigated whether cSBP is more

D De-Wei An

Fibromuscular Dysplasia: Emerging Concepts Beyond the International Consensus

Hypertension. 2026 Apr 29. doi: 10.1161/HYPERTENSIONAHA.125.25633. Online ahead of print.ABSTRACTThe First International Consensus on the diagnosis and management of fibromuscular dysplasia is a landmark document. Since its publication in 2019, important research has been ongoing in the field. In th

T Tom Robberechts

Experiences of Racism and Risk of Preeclampsia in the Black Women's Health Study

Hypertension. 2026 Apr 29. doi: 10.1161/HYPERTENSIONAHA.125.26454. Online ahead of print.ABSTRACTBACKGROUND: Black women in the United States experience higher rates of preeclampsia incidence, severity, and case fatality than White women, which contributes to cardiovascular disease disparities. Diff

S S Michelle Ogunwole

Bio-inspired metamaterial structured small-diameter vascular grafts for emulation of native arterial mechanics

J Mater Chem B. 2026 Apr 28. doi: 10.1039/d6tb00178e. Online ahead of print.ABSTRACTTo address the issue that the mechanical strength and compliance of traditional small-diameter artificial blood vessels are difficult to balance, leading to easy thrombosis and subsequent failure after transplantatio

X Xianhui Cai

Evaluating ejection dynamic parameters for assessing severe aortic stenosis

Caspian J Intern Med. 2026 Jan 21;17(1):106-112. doi: 10.22088/cjim.17.1.106. eCollection 2026.ABSTRACTBACKGROUND: Accurate diagnosis of aortic stenosis (AS) severity is crucial for effective treatment. This study aimed to define cutoff values for aortic ejection dynamic parameters, including ejecti

M Mohammad Reza Aghajankhah

Monocytes in HIV associated atherosclerosis: A review of pathogenesis and clinical implications

Caspian J Intern Med. 2026 Jan 11;17(1):1-13. doi: 10.22088/cjim.17.1.1. eCollection 2026.ABSTRACTAtherosclerosis, a chronic inflammatory disease of arterial walls, remains a leading cause of global mortality, with ischemic heart disease (IHD) and stroke as primary contributors. In people living wit

P Peyman Eini

Investigating subclinical myocardial ischemia by measuring carotid intima-media thickness using Doppler Ultrasound in patients with acute cardiac ischemia

Caspian J Intern Med. 2026 Jan 21;17(1):97-105. doi: 10.22088/cjim.17.1.97. eCollection 2026.ABSTRACTBACKGROUND: The present study aimed to evaluate the relationship between Carotid intima-media thickening (CIMT) with subclinical myocardial ischemia in acute cardiac ischemia (ACI) patients.METHODS:

Y Yasaman Zeid Shafiei

Can dobutamine stress echocardiography predict improvement of left ventricular dyssynchrony after coronary artery bypass grafting?

Caspian J Intern Med. 2026 Jan 21;17(1):158-162. doi: 10.22088/cjim.17.1.158. eCollection 2026.ABSTRACTBACKGROUND: For patients with advanced, diffuse Coronary artery disease (CAD), surgical myocardial revascularization via coronary artery bypass grafting (CABG) continues to represent the gold stand

R Rezvanieh Salehi

Detecting coronary artery disease among the individuals with left-sided dominant coronary circulation

Caspian J Intern Med. 2026 Jan 21;17(1):173-180. doi: 10.22088/cjim.17.1.173. eCollection 2026.ABSTRACTBACKGROUND: Investigating the importance of exercise tolerance test (ETT) in the diagnosis of coronary artery disease (CAD) among people with left-sided dominant coronary circulation is very import

M Majid Saraei Koushki

Cardiovascular Benefits of Salvia miltiorrhiza (Danshen) Supplementation: Bioactive Constituents, Mechanisms, Clinical Evidence and Implications for Nutritional Care

Food Sci Nutr. 2026 Apr 26;14(5):e71755. doi: 10.1002/fsn3.71755. eCollection 2026 May.ABSTRACTCardiovascular diseases (CVDs) remain the leading cause of mortality worldwide, creating interest in adjunctive strategies that complement standard care. Salvia miltiorrhiza (Danshen), a traditional Chines

A Akash Vikal

IFN-γ and IL-17A Exhibit Opposing Roles in Age-Related Blood Pressure Dysregulation

Int J Hypertens. 2026 Apr 27;2026:8370291. doi: 10.1155/ijhy/8370291. eCollection 2026.ABSTRACTBACKGROUND: The inflammatory pathophysiology of hypertension involves interactions between innate and adaptive immune pathways. While interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF-α) have estab

L Lweendo Muchaili

Construction and Validation of a Nomogram Based on Preoperative Inflammatory Indicators for Predicting Acute Kidney Injury After Pancreaticoduodenectomy

J Inflamm Res. 2026 Apr 23;19:588367. doi: 10.2147/JIR.S588367. eCollection 2026.ABSTRACTBACKGROUND: Acute kidney injury (AKI) after pancreaticoduodenectomy is common and early identification of such patients is critical. Inflammation contributes significantly to the onset of postoperative acute kid

W Wenwen Zhang