Ann Med. 2026 Dec;58(1):2622182. doi: 10.1080/07853890.2026.2622182. Epub 2026 Jan 30.ABSTRACTBACKGROUND: This research aimed to explore the potential role of heparin-binding protein (HBP) as a prognostic biomarker for adverse events among individuals diagnosed with ST-segment elevation myocardial i
Pharmacoepidemiol Drug Saf. 2026 Feb;35(2):e70323. doi: 10.1002/pds.70323.ABSTRACTPURPOSE: This nationwide cohort study examined the effects of discontinuation versus continuation of renin-angiotensin system inhibitors (RASis) on major renal and cardiovascular outcomes after the estimated glomerular
No abstractLiver Int. 2025 Aug;45(8):e70245. doi: 10.1111/liv.70245.NO ABSTRACTPMID:41614333 | DOI:10.1111/liv.70245
J Am Heart Assoc. 2026 Jan 30:e046142. doi: 10.1161/JAHA.125.046142. Online ahead of print.ABSTRACTBACKGROUND: The DCP (Diuretic Comparison Project), a pragmatic trial, evaluated whether chlorthalidone compared with hydrochlorothiazide would reduce the risk of nonfatal cardiovascular disease or nonc
J Am Heart Assoc. 2026 Jan 30:eJAHA2025043028T. doi: 10.1161/JAHA.125.043028. Online ahead of print.ABSTRACTBACKGROUND: Intracranial arteriosclerosis (large- and small-vessel disease) is considered a risk factor for major neurological disorders, such as stroke, cognitive impairment, and dementia. Wh
J Am Heart Assoc. 2026 Jan 30:e044333. doi: 10.1161/JAHA.125.044333. Online ahead of print.ABSTRACTBACKGROUND: Transcatheter edge-to-edge mitral valve repair is a key therapeutic option for patients with severe symptomatic mitral regurgitation at high surgical risk. This prospective study aimed to d
J Am Heart Assoc. 2026 Jan 30:e043845. doi: 10.1161/JAHA.125.043845. Online ahead of print.ABSTRACTBACKGROUND: Markers of renal function have been added to the Predicting Risk of Cardiovascular Disease Events and Systematic Coronary Risk Evaluation cardiovascular risk calculators to enhance risk pre
Circulation. 2026 Jan 30. doi: 10.1161/CIRCULATIONAHA.125.075951. Online ahead of print.ABSTRACTBACKGROUND: Oscillatory shear stress (OSS), resulting from disturbed blood flow, is implicated in atherosclerotic plaque formation by incompletely understood mechanisms. This study aims to elucidate the i
J Am Heart Assoc. 2026 Jan 30:e040725. doi: 10.1161/JAHA.124.040725. Online ahead of print.ABSTRACTBACKGROUND: We aimed to evaluate the prognostic effect of serum high-density lipoprotein cholesterol (HDL-c) concentration on the risk of vascular events and functional prognosis in patients with strok
J Am Heart Assoc. 2026 Jan 30:e047458. doi: 10.1161/JAHA.125.047458. Online ahead of print.ABSTRACTComplex bidirectional interactions between the nervous and cardiovascular systems are integrated through the heart-brain axis, a physiological pathway that governs both neural regulation of cardiovascu
Circulation. 2026 Jan 30. doi: 10.1161/CIRCULATIONAHA.125.075275. Online ahead of print.ABSTRACTBACKGROUND: Systemic embolic events (SEEs) are a serious but underrecognized complication of atrial fibrillation. Although non-vitamin K antagonist oral anticoagulants prevent ischemic stroke (IS), their
Hypertension. 2026 Jan 30. doi: 10.1161/HYPERTENSIONAHA.125.26006. Online ahead of print.ABSTRACTBACKGROUND: The immune system is emerging as a key player in driving cardiac remodeling in heart failure with preserved ejection fraction (HFpEF). Galectin-1 (Lgals1) is a carbohydrate-binding protein th
Circ Cardiovasc Imaging. 2026 Jan 30:e018979. doi: 10.1161/CIRCIMAGING.125.018979. Online ahead of print.ABSTRACTBACKGROUND: Physiologic interaction between the cardiovascular and renal systems is pivotal in the understanding of disease and as a target for therapeutic interventions, as highlighted i
CONCLUSIONS: In this large multicenter cohort, MFR derived from ^(13)N-ammonia PET myocardial perfusion imaging is a strong, independent predictor of all-cause mortality, even in patients with normal perfusion. An MFR of ≤2.0 identifies elevated risk, while higher values are associated with improved
Dermatol Reports. 2026 Jan 30. doi: 10.4081/dr.2026.10213. Online ahead of print.ABSTRACTPsoriasis is a chronic inflammatory skin disease associated with multiple comorbidities, including erectile dysfunction (ED). Data on the sexual health of male psoriasis patients in Vietnam are limited. We inves
CNS Neurosci Ther. 2026 Feb;32(2):e70769. doi: 10.1002/cns.70769.ABSTRACTBACKGROUND: Hypertensive cognitive impairment is associated with increased iron deposition in deep gray matter. This study aimed to evaluate the potential clinical application of quantitative susceptibility mapping (QSM)-based
Front Pharmacol. 2026 Jan 14;16:1718008. doi: 10.3389/fphar.2025.1718008. eCollection 2025.ABSTRACTMyocardial ischemia-reperfusion injury (MIRI) represents a significant challenge in the treatment of cardiovascular diseases, with its complex pathogenesis involving multiple signaling pathways, such a
Front Cardiovasc Med. 2026 Jan 14;12:1674486. doi: 10.3389/fcvm.2025.1674486. eCollection 2025.ABSTRACTArtificial intelligence (AI) is revolutionizing cardiovascular imaging, with aortic computed tomography angiography (CTA) emerging as a prominent area of application. CTA imaging is essential for t
No abstractJ Endocr Soc. 2026 Jan 28;10(2):bvaf213. doi: 10.1210/jendso/bvaf213. eCollection 2026 Feb.NO ABSTRACTPMID:41614010 | PMC:PMC12849365 | DOI:10.1210/jendso/bvaf213
Front Endocrinol (Lausanne). 2026 Jan 14;16:1714219. doi: 10.3389/fendo.2025.1714219. eCollection 2025.ABSTRACTAIM: The aim was to carry out a preliminary investigation to identify new biomarkers and test the suitability of the pro-inflammatory nuclear protein, HMGB1, as a potential diagnostic or tr
Front Endocrinol (Lausanne). 2026 Jan 14;16:1730404. doi: 10.3389/fendo.2025.1730404. eCollection 2025.ABSTRACTBACKGROUND: The triglyceride-glucose (TyG) index is a simple and reliable marker of insulin resistance and is associated with cardiovascular risk. Epicardial adipose tissue (EAT) volume ref
Front Cell Dev Biol. 2026 Jan 14;13:1754988. doi: 10.3389/fcell.2025.1754988. eCollection 2025.ABSTRACTBACKGROUND: Glioblastoma (GBM) is an aggressive malignancy of the central nervous system characterized by rapid progression, therapeutic resistance, and poor prognosis. Epithelial-mesenchymal trans
Ann Intern Med Clin Cases. 2026 Jan;5(1):e250735. doi: 10.7326/aimcc.2025.0735. Epub 2026 Jan 6.ABSTRACTRoundabout guidance receptor 4 (ROBO4) germline variants [including c.695C>T (p.Thr232Met)] have been linked with bicuspid aortic valve and thoracic aortic aneurysm. However, the precise nature of
Front Nutr. 2026 Jan 14;12:1728865. doi: 10.3389/fnut.2025.1728865. eCollection 2025.ABSTRACTUnhealthy diets are major contributors to the global burden of non-communicable diseases, particularly cardiovascular disease and metabolic syndrome, where dietary fat quality plays a critical role. Among di
