Sirtuin 1 modulation unlocks the therapeutic potential of sodium-glucose co-transporter 2 inhibitors (SGLT2i) in calcific aortic valve stenosis

Cardiovasc Res. 2026 Sep 8:cvag199. doi: 10.1093/cvr/cvag199. Online ahead of print.ABSTRACTBACKGROUND: Calcific aortic valve stenosis (AS) affects 3% of older adults and lacks medical treatment. The deacetylase Sirtuin 1 (SIRT1) could be involved in many pathways linked to AS progression. Sodium-gl

V Vincenza Valerio

Efficacy and safety of direct oral anticoagulants for the treatment of non-triple-positive antiphospholipid syndrome-associated pulmonary thromboembolism

Zhonghua Jie He He Hu Xi Za Zhi. 2026 Sep 12;49(9):998-1004. doi: 10.3760/cma.j.cn112147-20251214-00789.ABSTRACTObjective: To evaluate the efficacy and safety of direct oral anticoagulants (DOAC) in the treatment of non-triple-positive antiphospholipid syndrome (APS)-associated pulmonary thromboembo

C C C Hu

Kawasaki disease in children with initial manifestations mimicking deep neck infections: a clinical analysis of 14 cases

Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2026 Aug 7;61(8):912-916. doi: 10.3760/cma.j.cn115330-20251110-00590.ABSTRACTObjective: To investigate the clinical characteristics of Kawasaki disease (KD) in children who initially present with symptoms of deep neck infections (DNIs). Methods: A retro

L L L Hao

Predictive value of next-generation sequencing-based measurable residual disease quantitative stratification for early disease progression in newly diagnosed multiple myeloma after induction therapy

Zhonghua Xue Ye Xue Za Zhi. 2026 Jul 14;47(7):667-675. doi: 10.3760/cma.j.cn121090-20260403-00173.ABSTRACTObjective: To evaluate the predictive value of next-generation sequencing (NGS) -based quantitative minimal residual disease (MRD) stratification for early disease progression in patients newly

Y Y H Peng

The correlation between lymphocyte subsets before autologous hematopoietic stem cell transplantation and hematopoietic reconstruction and recurrence after transplantation in multiple myeloma

Zhonghua Xue Ye Xue Za Zhi. 2026 Jun 14;47(6):582-586. doi: 10.3760/cma.j.cn121090-20260115-00028.ABSTRACTThe clinical data of 57 patients with multiple myeloma (MM) who underwent autologous hematopoietic stem cell transplantation (auto-HSCT) at the Second Affiliated Hospital of Anhui Medical Univer

L L L Zhang

Comparison of clinical outcomes of DCB angioplasty versus DES implantation in patients with recently diagnosed cancer and coronary artery disease undergoing PCI

Zhonghua Yi Xue Za Zhi. 2026 Sep 8;106(33):3492-3498. doi: 10.3760/cma.j.cn112137-20260430-01184.ABSTRACTObjective: To investigate the difference of clinical outcomes of drug-coated balloon (DCB) angioplasty and drug-eluting stent (DES) implantation in patients with recently diagnosed cancer and con

X X H Li

Glucagon-like peptide-1 receptor agonists: from metabolic regulation to rheumatic disease therapy

Zhonghua Yi Xue Za Zhi. 2026 Sep 8;106(33):3431-3437. doi: 10.3760/cma.j.cn112137-20260312-00692.ABSTRACTGlucagon-like peptide-1 (GLP-1) receptor agonists (GLP-1RA), originally developed for type 2 diabetes mellitus and obesity, have attracted considerable attention in rheumatology due to their plei

W W H Xie

Efficacy of ripretinib in advanced gastrointestinal stromal tumor and treatment options after resistance: a retrospective real-world study​

Zhonghua Wei Chang Wai Ke Za Zhi. 2026 Aug 25;29(8):1058-1066. doi: 10.3760/cma.j.cn441530-20251021-00394.ABSTRACTObjective: To investigate the clinical efficacy, safety, and post-resistance treatment strategies of ripretinib in the treatment of advanced gastrointestinal stromal tumors (GIST), and t

X X N Yin

Development of a multidisciplinary intelligent nexus for decision support in digestive malignancies and its application to comprehensive perioperative management in older patients

Zhonghua Wei Chang Wai Ke Za Zhi. 2026 Aug 25;29(8):1004-1013. doi: 10.3760/cma.j.cn441530-20260529-00214.ABSTRACTWe describe the technical architecture of the Huashan Multidisciplinary Intelligent Nexus for Decision Support in Digestive Malignancies (HS-MIND), developed using a reasoning-augmented

Y Y M Zhou

Collaborative diagnosis and treatment of children with extremely severe obstructive sleep apnea involving multi-system damage

Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2026 Jul 7;61(7):793-797. doi: 10.3760/cma.j.cn115330-20250713-00369.ABSTRACTObjective: To explore the multidisciplinary collaborative diagnosis and treatment for children with extremely severe obstructive sleep apnea (OSA) complicated by multisystem in

M M Li

Expert consensus on the application of bone cement in the treatment of diabetic wounds (2026 edition)

Zhonghua Shao Shang Yu Chuang Mian Xiu Fu Za Zhi. 2026 Aug 20;42(8):703-716. doi: 10.3760/cma.j.cn501225-20260128-00052.ABSTRACTDiabetic wounds, including diabetic foot ulcers, represent one of the severe complications associated with diabetes mellitus, which progress rapidly, are difficult to treat

B Burns and Trauma Branch of Chinese Geriatrics Society

Across-sectional study on the association between steatotic liver disease and its subtypes, cardiovascular health status, and extrahepatic comorbidity

Zhonghua Gan Zang Bing Za Zhi. 2026 Aug 20;34(8):757-768. doi: 10.3760/cma.j.cn501113-20260609-00241.ABSTRACTObjective: To investigate the association between steatotic liver disease (SLD) and its clinical subtypes with metabolic syndrome (MetS), type 2 diabetes mellitus (T2DM), hypertension (HTN),

J J B Guan

The impact of hand-transmitted vibration from municipal maintenance workers on health

Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2026 Aug 20;44(8):671-676. doi: 10.3760/cma.j.cn121094-20250318-00105.ABSTRACTObjective: To investigate the health effects of hand-transmitted vibration operations on municipal maintenance workers, and to provide a scientific basis for effective preven

C C H Xu

Elevated lipoprotein(a) and prevalent cardiovascular disease burden in treated hypertension

J Clin Lipidol. 2026 Aug 22:S1933-2874(26)00490-3. doi: 10.1016/j.jacl.2026.08.008. Online ahead of print.ABSTRACTBACKGROUND: Elevated lipoprotein(a) [Lp(a)] is associated with atherosclerotic cardiovascular disease across multiple clinical settings, but its relationship with prevalent cardiovascula

N Nicolás F Renna

Tuberoeruptive xanthomas: undiagnosed warning signs of familial dysbetalipoproteinemia in a 38-year-old male with premature ischemic heart disease

J Clin Lipidol. 2026 Aug 22:S1933-2874(26)00482-4. doi: 10.1016/j.jacl.2026.08.007. Online ahead of print.ABSTRACTFamilial dysbetalipoproteinemia (FD) is a rare autosomal recessive inherited dyslipidemia caused by homozygous variants of the ε2 allele in the apolipoprotein E (APOE) gene. Phenotypical

J Jonas Pedersen

Direct transfer to primary percutaneous coronary intervention centres following out-of-hospital cardiac arrest: longer term outcomes and influences on survival

Heart. 2026 Sep 7:heartjnl-2026-328408. doi: 10.1136/heartjnl-2026-328408. Online ahead of print.ABSTRACTOBJECTIVE: Myocardial infarction is a leading cause of out-of-hospital cardiac arrest (OHCA). In patients with OHCA due to suspected acute coronary occlusion, direct transfer to a centre capable

A Alexander Hunt

Anti-HER2 therapy-associated echocardiography-related cardiac dysfunction and severe outcomes: Comparison of disproportionality and report-level cluster analyses

Br J Clin Pharmacol. 2026 Sep 7. doi: 10.1002/bcp.70810. Online ahead of print.ABSTRACTAIMS: Conventional pharmacovigilance identifies drug-event reporting signals but not heterogeneity among anti-HER2 cardiac dysfunction reports. We benchmarked this association using disproportionality analysis and

J Junjie Liu

Nationwide LDL-C goal attainment in high-risk and very-high-risk patients in Denmark: real-world lipid management and simulated impact of guideline implementation

Open Heart. 2026 Sep 7;13(2):e004265. doi: 10.1136/openhrt-2026-004265.ABSTRACTAIM: Low-density lipoprotein cholesterol (LDL-C) goal attainment remains suboptimal among individuals with or at risk for atherosclerotic cardiovascular disease (ASCVD). We evaluated contemporary nationwide real-world LDL

A Abdullahi Ahmed Mohamed

Approach to Urticaria and Angioedema in the Older Patient

J Allergy Clin Immunol Pract. 2026 Sep;14(9):1989-1997. doi: 10.1016/j.jaip.2026.05.038.ABSTRACTChronic spontaneous urticaria (CSU) and angioedema in the older population (typically >65 years) present unique diagnostic and management challenges due to physiological aging, frequent comorbidities, and

T Tukisa Smith

Preparation and application of soy protein isolate-filled sucrose composite particles in sugar-reduced chocolate via protein-mediated morphological modulation

Food Res Int. 2026 Nov 1;243(Pt 2):120427. doi: 10.1016/j.foodres.2026.120427. Epub 2026 Aug 18.ABSTRACTExcessive sugar consumption is a major contributor to obesity, diabetes, and cardiovascular diseases, driving the urgent need for effective sugar reduction strategies in food products. This study

Y Yanke Wang

European Respiratory Society clinical practice guidelines update for the treatment of pulmonary arterial hypertension

Eur Respir J. 2026 Sep 7:2601178. doi: 10.1183/13993003.01178-2026. Online ahead of print.ABSTRACTBACKGROUND: Pulmonary arterial hypertension (PAH) is a severe, progressive disease of the small pulmonary arteries. These guidelines provide updated evidence-based recommendations for the treatment of P

G Gabor Kovacs

Post-transplant CKLM: extending integrated clinical trial design to solid organ transplant recipients

No abstractGut. 2026 Sep 7:gutjnl-2026-340432. doi: 10.1136/gutjnl-2026-340432. Online ahead of print.NO ABSTRACTPMID:42705694 | DOI:10.1136/gutjnl-2026-340432

A Alessandro Mattina

Systemic sclerosis presenting as recurrent pericardial effusion despite repeatedly negative multiplex antinuclear antibody results

BMJ Case Rep. 2026 Sep 7;19(9):e272372. doi: 10.1136/bcr-2026-272372.ABSTRACTA woman in her 70s was admitted three times over 22 months with recurrent pericardial effusions. A multiplex antinuclear antibody (ANA) assay by chemiluminescent enzyme immunoassay, reported only as a combined index, was re

T Tsubasa Omae

Intravascular large B-cell lymphoma with reversible central hypopituitarism

BMJ Case Rep. 2026 Sep 7;19(9):e274418. doi: 10.1136/bcr-2026-274418.ABSTRACTWe report the case of a woman in her late 60s who presented to our hospital with fever and general fatigue. Investigation revealed bicytopenia, splenomegaly and central hypothyroidism. Brain MRI revealed enlargement of the

R Ryuichiro Yamasaki