Artificial Intelligence (AI)-Facilitated Analysis of Single-Image Tissue Doppler Signal to Characterize Right Ventricular Dysfunction

Echocardiography. 2026 Apr;43(4):e70447. doi: 10.1111/echo.70447.ABSTRACTBACKGROUND: Quantitative assessment of right ventricular (RV) function by transthoracic echocardiogram (TTE) commonly relies on tricuspid annular plane systolic excursion (TAPSE) and lateral tricuspid annulus peak systolic velo

X Xin Tan

Feasibility of quantitative pulmonary function imaging in real-world cardiovascular magnetic resonance

Int J Cardiovasc Imaging. 2026 Apr 10. doi: 10.1007/s10554-026-03702-z. Online ahead of print.ABSTRACTProviding insights into the feasibility of pulmonary function assessment in real-world cardiovascular magnetic resonance (CMR) practice by applying Phase-REsolved FUnctional Lung imaging (PREFUL). W

J Jan Gröschel

Correction: Glucagon-Like Peptide-1 and Dual Incretin Agonists in Type 2 Diabetes with Peripheral Artery Disease: A Systematic Review and Meta-Analysis of Vascular, Cardiovascular, Metabolic, and Mortality Outcomes

No abstractCurr Diab Rep. 2026 Apr 10;26(1):9. doi: 10.1007/s11892-026-01622-9.NO ABSTRACTPMID:41961366 | DOI:10.1007/s11892-026-01622-9

L Larissa Araújo de Lucena

Machine learning integrated clinical-proteomics data identifies a 6-protein panel signature for atherosclerotic severity and enhanced patient stratification

Mol Biomed. 2026 Apr 10;7(1):49. doi: 10.1186/s43556-026-00438-z.ABSTRACTAtherosclerosis, a major cause of adverse cardiovascular events and mortality rates worldwide, stems from sustained lipid accumulation and subsequent chronic inflammation within the arterial walls. An early identification of pa

M Mª Jesús Extremera-García

Targeting the Microglia-Astrocyte OSM-OSMR Axis Restores Blood-Brain Barrier Integrity After Experimental Cerebral Ischemia-Reperfusion in Mice

Mol Neurobiol. 2026 Apr 10;63(1):557. doi: 10.1007/s12035-026-05810-2.ABSTRACTBlood-brain barrier (BBB) disruption is a major contributor to brain injury following ischemic stroke. However, current endothelial-targeted strategies for BBB protection have shown limited clinical efficacy. Glial cells a

L Lianxin Li

Native liver survival and genetic associations in Korean patients with Alagille syndrome

Eur J Pediatr. 2026 Apr 10;185(5):252. doi: 10.1007/s00431-026-06917-3.ABSTRACTAlagille syndrome (ALGS) is a rare multisystem disorder most commonly resulting from pathogenic variants in JAG1 and, less frequently, NOTCH2. We evaluated long-term native liver survival (NLS) and overall survival (OS) i

S Shinjie Choi

Recommendations from guidelines for the prevention of venous thromboembolism in pregnant women with inherited thrombophilia

Arch Gynecol Obstet. 2026 Apr 10;313(1):162. doi: 10.1007/s00404-026-08389-0.ABSTRACTWomen with inherited thrombophilia represent more than 15% of the pregnant population. 20-50% of pregnancy-related venous thromboembolism (VTE) is associated with at least one inherited thrombophilia, which increase

W Werner Rath

Plasma neurofilament light chain and glial fibrillary acidic protein in the differential diagnosis of acute vertigo in the emergency department

J Neurol. 2026 Apr 10;273(5):264. doi: 10.1007/s00415-026-13799-w.ABSTRACTBACKGROUND: Distinguishing posterior circulation stroke (PCS) from peripheral or other causes of acute vertigo can be challenging. Blood biomarkers, such as plasma neurofilament light chain (pNfL) and glial acidic fibrillary p

M Melanie Haidegger

A machine-learning-based tool for stroke risk prediction in blunt cerebrovascular injury: development and preliminary evaluation

Eur J Trauma Emerg Surg. 2026 Apr 10;52(1):123. doi: 10.1007/s00068-026-03172-x.ABSTRACTPURPOSE: Stroke risk correlates with the Biffl grading system in blunt cerebrovascular injury (BCVI). Although anti-thrombotic therapy is the mainstay of stroke prevention, no point-of-care clinical decision-supp

V Victoria Wagner

Editorial Expression of Concern: Wnt/β-catenin-driven EMT regulation in human cancers

No abstractCell Mol Life Sci. 2026 Apr 10;83(1):200. doi: 10.1007/s00018-026-06193-2.NO ABSTRACTPMID:41961255 | DOI:10.1007/s00018-026-06193-2

L Lin Yang

Protective effects of Pelargonium sidoides against oxidative stress and inflammation in experimental mesenteric ischemia-reperfusion injury

J Mol Histol. 2026 Apr 10;57(2):136. doi: 10.1007/s10735-026-10790-7.ABSTRACTPelargonium sidoides is traditionally used in South African herbal medicine for the treatment of respiratory tract infections and has been commercialized in over 50 countries as EPs® 7630. While most clinical applications f

S Simge Unay

A novel immunoassay applying lanthanide-based metal-organic frameworks to detect thrombomodulin in human serum for early vascular endothelial injury diagnosis

No abstractMikrochim Acta. 2026 Apr 10;193(5):303. doi: 10.1007/s00604-026-08013-7.NO ABSTRACTPMID:41961135 | DOI:10.1007/s00604-026-08013-7

R Ruitian Fan

Transient Receptor Potential Channel Signaling in Hypertension: Mechanisms, Translation, and Therapeutic Targeting

Turk Kardiyol Dern Ars. 2026 Apr 10. doi: 10.5543/tkda.2026.34864. Online ahead of print.ABSTRACTArterial hypertension (HT) is a major risk factor in the pathogenesis of cardiovascular diseases and has a high prevalence. The pathogenesis of primary HT, which accounts for the majority of HT cases, ha

A Algül Dilara Dokumacı

Romosozumab versus teriparatide and risk of all-cause mortality in patients with osteoporosis: a real-world propensity score-matched cohort study

Osteoporos Int. 2026 Apr 10. doi: 10.1007/s00198-026-07968-w. Online ahead of print.ABSTRACTThis study compared romosozumab and teriparatide for osteoporosis treatment using real-world data. Romosozumab was linked to significantly lower mortality, especially in older adults, without added cardiovasc

S Sung Huang Laurent Tsai

Differentiating long QT syndrome genotypes using electrocardiographic geometric parameterization and machine learning approaches

Biomed Phys Eng Express. 2026 Apr 10;12(2). doi: 10.1088/2057-1976/ae58ae.ABSTRACTLong QT Syndrome (LQTS) is an inherited cardiac disorder characterized by dysfunctional cardiac ion channels, which result in prolonged QT intervals on electrocardiograms (ECGs). LQTS can lead to severe clinical manife

M Martina Srutova

The Assessment of Diastolic and Systolic Function in Kawasaki Disease Using Myocardial Strain Imaging and Tissue Doppler Imaging: A Systematic Review and Meta-Analysis

Echocardiography. 2026 Apr;43(4):e70446. doi: 10.1111/echo.70446.ABSTRACTBACKGROUND: Kawasaki disease (KD) is an acute febrile vasculitis that may lead to myocardial dysfunction despite its self-limiting nature. This study aimed to evaluate the impact of KD on systolic and diastolic function using m

Y Yan He

Perioperative Continuation of Interleukin-1 Blockade in Chronic Constrictive Pericarditis: Imaging-Guided Surgical Decision

JACC Case Rep. 2026 Apr 9:107519. doi: 10.1016/j.jaccas.2026.107519. Online ahead of print.ABSTRACTBACKGROUND: Interleukin (IL)-1 inhibitors have transformed pericarditis management by controlling inflammation and preventing relapse. Their use around pericardiectomy in patients with fixed constricti

R Rochell Issa

Visualization of the True Left Ventricular Apex on Transthoracic Echocardiography

Echocardiography. 2026 Apr;43(4):e70455. doi: 10.1111/echo.70455.ABSTRACTVisualizing the true cardiac apex using transthoracic echocardiography (TTE) remains challenging. The American Society of Echocardiography guidelines describe the left ventricle as tapering elliptically at the apex, with foresh

N Nagisa Okazaki

Albumin-Bilirubin Score and Subclinical Right Ventricular Dysfunction After Repair of Tetralogy of Fallot

Echocardiography. 2026 Apr;43(4):e70462. doi: 10.1111/echo.70462.ABSTRACTBACKGROUND: Right ventricular (RV) dysfunction is a key determinant of long-term morbidity in patients following surgical repair of tetralogy of Fallot (TOF). Identifying practical biomarkers for early detection of right-sided

E Erhan Sönmez

Prognostic value of peak tricuspid regurgitation velocity in hospitalized patients with heart failure with preserved ejection fraction: an multi-institutional study

Ann Med. 2026 Dec;58(1):2651008. doi: 10.1080/07853890.2026.2651008. Epub 2026 Apr 10.ABSTRACTOBJECTIVE: Heart failure with preserved ejection fraction (HFpEF) represents a significant clinical challenge with limited prognostic markers. The prognostic value of Doppler-derived peak tricuspid regurgit

C Chieh-Yu Chang

A comprehensive review of GLP-1 and aerobic training in cardiovascular disease management

Clin Hemorheol Microcirc. 2026 Apr 10:13860291251414840. doi: 10.1177/13860291251414840. Online ahead of print.ABSTRACTSecreted by enteroendocrine cells in the gastrointestinal tract, glucagon-like peptide-1 (GLP-1) is pivotal in the management of glycemic variability, as it promotes insulin secreti

N Negin Kordi

Molecular insights into the binding of curcumin, γ-oryzanol, and sesamin to cyclooxygenase-2 (COX-2): a computational study

J Biomol Struct Dyn. 2026 Apr 10:1-13. doi: 10.1080/07391102.2026.2655804. Online ahead of print.ABSTRACTCyclooxygenase-2 (COX-2) is a key therapeutic target for inflammatory diseases, cancer, and osteoarthritis (OA). Thus, several COX-2 inhibitors have been developed. However, their clinical use ha

P Peerayut Dammak

Role of circadian gene expression in the divergent effects of intermittent hypoxia and sleep fragmentation on blood pressure

Clin Sci (Lond). 2026 Apr 15;140(4):639-650. doi: 10.1042/CS20258876.ABSTRACTCircadian clock genes, such as BMAL1 (brain and muscle aryl-hydrocarbon receptor nuclear translocator-like 1), CLOCK (circadian locomotor output cycles kaput), PER1/2/3 (period 1/2/3), and CRY1/2 (cryptochrome 1/2), can pla

E Eileen Chen

Case report of a patient with acenocoumarol resistance following therapy for infective endocarditis with rifampicin and gentamicin combination therapy

Cardiovasc J Afr. 2026 Feb 20;37(1):8-9. doi: 10.5830/CVJA-2025-090. Epub 2026 Feb 20.ABSTRACTVitamin K antagonists (VKAs) are essential for anticoagulation in patients with mechanical heart valves, but are affected by drug interactions, particularly with rifampicin - a potent inducer of CYP2C9 that

M M Luszczyn