Antitumoral and cardioprotective roles of statins: underlying types, mechanisms, current evidence, and emerging perspectives

Clin Transl Oncol. 2026 Jan 30. doi: 10.1007/s12094-025-04162-y. Online ahead of print.ABSTRACTStatins are widely recognized as cholesterol-lowering agents that reduce the risk of myocardial infarction and stroke, but emerging evidence highlights their broader therapeutic potential, particularly in

I Ibrahim El Sayed

Evolving Mineralocorticoid Receptor Antagonism: a Narrative Review on Differences between Steroidal MRAs, Non-Steroidal MRAs and Aldosterone Synthase Inhibitors in Cardiorenal Disease

Curr Heart Fail Rep. 2026 Jan 30;23(1):5. doi: 10.1007/s11897-026-00740-5.ABSTRACTPURPOSE OF REVIEW: This review explores the evolution of mineralocorticoid receptor antagonists (MRAs) in cardiorenal disease, comparing steroidal MRAs with newer non-steroidal MRAs and emerging aldosterone synthase in

J Jonas Erzeel

The RNA delivery dilemma-lipid versus polymer nanoparticle platforms

Drug Deliv Transl Res. 2026 Jan 30. doi: 10.1007/s13346-026-02044-6. Online ahead of print.ABSTRACTSince the first market authorization of RNA therapies, just eight years ago, the field has witnessed an extraordinary expansion, ranging from hepatic delivery for rare genetic diseases to global-scale

C Cláudia Martins

Effect of prehospital 12-Lead electrocardiography on the emergent medical system for ST-Segment-Elevation myocardial infarction during the coronavirus disease 2019 (COVID-19) pandemic: results from the K-ACTIVE registry

No abstractCardiovasc Interv Ther. 2026 Jan 30. doi: 10.1007/s12928-026-01243-9. Online ahead of print.NO ABSTRACTPMID:41615558 | DOI:10.1007/s12928-026-01243-9

Y Yasuhiro Tanabe

Brilliant blue G enhances cardiac function and suppresses ventricular arrhythmias by attenuating inflammation and fibrosis after post-myocardial infarction in rats

Purinergic Signal. 2026 Jan 30;22(1):15. doi: 10.1007/s11302-025-10116-4.ABSTRACTMyocardial infarction (MI) is a leading cause of heart failure and ventricular arrhythmias, driven by excessive inflammation and adverse cardiac remodeling. The purinergic P2X7 receptor (P2X7R) plays a critical role in

Z Zefei Jiang

Ptbp2 Alleviates Neuroinflammation and Blood-brain Barrier Disruption via Modulating Microglial Polarization in Ischemic Stroke

Mol Neurobiol. 2026 Jan 30;63(1):408. doi: 10.1007/s12035-026-05704-3.ABSTRACTDamage following ischemic stroke is worsened by microglial activation and subsequent neuroinflammation. Polypyrimidine tract binding protein 2 (Ptbp2) can influence the chemotaxis and repolarization of cancer-related macro

W Wenting Xu

Diastolic Dysfunction is Associated with Liver Fibrosis and Insulin Resistance in Alcohol Use Disorder

J Gen Intern Med. 2026 Jan 30. doi: 10.1007/s11606-025-10106-7. Online ahead of print.ABSTRACTBACKGROUND: Alcohol use disorder (AUD) is associated with many health consequences, including cardiomyopathy with impaired systolic function, liver disease, and metabolic disturbances.OBJECTIVE: We aimed to

A Anna Hernández-Rubio

Lipid monitoring using non-invasive measurement technologies and machine learning: a systematic review

Arch Gynecol Obstet. 2026 Jan 30;313(1):71. doi: 10.1007/s00404-025-08254-6.ABSTRACTBACKGROUND: Cardiovascular diseases (CVD) are the leading cause of death among women, with risk increasing after menopause. Lipid levels are key biomarkers, yet conventional blood tests remain invasive and underutili

J Julia Endrass

Correction: VEGFC ameliorates salt‑sensitive hypertension and hypertensive nephropathy by inhibiting NLRP3 inflammasome via activating VEGFR3‑AMPK dependent autophagy pathway

No abstractCell Mol Life Sci. 2026 Jan 30;83(1):81. doi: 10.1007/s00018-025-06066-0.NO ABSTRACTPMID:41615477 | DOI:10.1007/s00018-025-06066-0

Q Qiuwen Wu

Correlation of White Matter Lesions, Cerebral Blood Flow, and Cognitive Decline in Patients With Alzheimer's Disease and Vascular Dementia

Arch Clin Neuropsychol. 2026 Jan 30;41(1):acaf113. doi: 10.1093/arclin/acaf113.ABSTRACTOBJECTIVE: This study investigated the relationship between white matter lesions (WMLs), cerebral blood flow (CBF), and cognitive decline in a mixed cohort of patients diagnosed with Alzheimer's disease (AD) and v

M Maobin Ye

Apathy and Depression Impact on Cognitive Decline: Neuropsychological Specificities across Neurodegenerative Diseases

Arch Clin Neuropsychol. 2026 Jan 30;41(1):acaf121. doi: 10.1093/arclin/acaf121.ABSTRACTOBJECTIVE: Apathy is a common symptom across neurodegenerative diseases with origins still debated. "Vascular apathy hypothesis" by Van der Mast suggests vascular pathologies precede apathy. Other evidence points

S Serena Oliveri

Attenuated Cyclooxygenase-Mediated Vasodilation in Cutaneous Microvasculature with No Difference in Platelet Aggregation in Women with Endometriosis

J Appl Physiol (1985). 2026 Jan 30. doi: 10.1152/japplphysiol.00865.2025. Online ahead of print.ABSTRACTEndometriosis is a systemic inflammatory disease known to increase the risk of cardiovascular disease. The inducible form of cyclooxygenase (COX), COX-2, is an inflammatory enzyme upregulated in e

A Auni C Williams

Baseline Nonperfusion and Deep Capillary Plexus Ischemia Predict Two-Year Retinal Nonperfusion Progression in Diabetic Retinopathy

Invest Ophthalmol Vis Sci. 2026 Jan 5;67(1):64. doi: 10.1167/iovs.67.1.64.ABSTRACTPURPOSE: The purpose of this study was to determine which baseline factors, including ultra-widefield fluorescein angiography (UWF-FA) nonperfusion and macular optical coherence tomography angiography (OCTA) metrics, p

A Anna M Busza

Complete or Partial Revascularization During Emergency PCI in a Patient With NSTEMI

JACC Case Rep. 2026 Jan 30:106792. doi: 10.1016/j.jaccas.2025.106792. Online ahead of print.ABSTRACTBACKGROUND: Optimal management of nonculprit lesions remains uncertain in patients with non-ST-segment elevation myocardial infarction (NSTEMI) during emergency percutaneous coronary intervention (PCI

S Shengjia Sun

Postoperative Atrial Arrhythmias After Lung Transplantation: A Single Center Analysis of Risk Factors, Management, and Outcomes

Clin Transplant. 2026 Feb;40(2):e70457. doi: 10.1111/ctr.70457.ABSTRACTBACKGROUND: Postoperative atrial arrhythmia (POAA) is common after lung transplant, but data on its implications and management are limited. This study assessed POAA incidence and timing, its association with mortality and rehosp

D Daniel M Chen

Stroke management challenges and innovations in Hungary and China: A comparative study

Ideggyogy Sz. 2026 Jan 30;79(1-2):17-24. doi: 10.18071/isz.79.0017.ABSTRACTBACKGROUND AND PURPOSE: Stroke is a leading cause of death globally, placing a particularly high burden on Hungary and China. Our study aimed to compare the epidemiology, acute management, and stroke prevention strategies bas

A Anna Gaál

Cytotoxic lesion of corpus callosum associated with cerebral venous sinus thrombosis

Ideggyogy Sz. 2026 Jan 30;79(1-2):69-72. doi: 10.18071/isz.79.0069.ABSTRACTIntroduction - Cytotoxic lesion of corpus callosum (CLOCC) is a rare but increasingly recognized entity. It is associated with various etiologies including drug-related toxicity, epilepsy, infections, metabolic disturbances,

I Inci Emekli

GLP-1 Receptor Agonists Are Associated With Reduced Mortality Following Diabetic Foot Ulcers: A Nationwide Observational Study

Diabetes Care. 2026 Jan 30:dc252120. doi: 10.2337/dc25-2120. Online ahead of print.ABSTRACTOBJECTIVE: This nationwide study aimed to identify factors associated with 1-year mortality following a first diabetic foot ulcer (DFU) using the French National Health Data System (SNDS). A secondary objectiv

J Jean-Baptiste Bonnet

Guideline commentary on the ESC/EACTS 2024 guidelines for atrial fibrillation: a focus on managing AF in the older population

Age Ageing. 2026 Jan 3;55(1):afag002. doi: 10.1093/ageing/afag002.ABSTRACTAtrial fibrillation (AF) is associated with increased risks of stroke, heart failure and mortality. Rate and rhythm control are used to manage symptoms and improve quality of life, and restoration of normal sinus rhythm is als

R Riyaz A Kaba

Long-term adherence to the new Nordic Nutrition Recommendations in relation to cardiovascular events and cardiometabolic biomarkers

Eur J Prev Cardiol. 2026 Jan 30:zwag057. doi: 10.1093/eurjpc/zwag057. Online ahead of print.ABSTRACTAIMS: Little evidence exists on the health implications of adherence to a diet in line with the updated Nordic Nutrition Recommendations (NNR2023). We estimated the association between long-term adher

S Stephanie G Pitt

Beyond BMI: The Predictive Value of Body Roundness Index for Cardiovascular Mortality and Related Disparities: A National Cohort Study of US Adults

Eur J Prev Cardiol. 2026 Jan 30:zwag055. doi: 10.1093/eurjpc/zwag055. Online ahead of print.ABSTRACTAIMS: Obesity, particularly visceral adiposity, is a key driver of cardiovascular mortality (CVM), yet conventional measures such as body mass index (BMI) inadequately capture fat distribution. The Bo

M Mohamed Ibrahim

Beyond the Pain: Patterns of Somatic Comorbidity in Patients With High-Impact Chronic Pain Referred to Specialised Interdisciplinary Treatment

Eur J Pain. 2026 Feb;30(2):e70217. doi: 10.1002/ejp.70217.ABSTRACTBACKGROUND: Chronic pain frequently co-occurs with multiple somatic comorbidities. However, little is known about how these conditions naturally cluster in patients with high-impact chronic pain. This study aimed to describe somatic c

J Julie Rønne Pedersen

EBF2 variant identified in a patient with atypical partial lipodystrophy causes adipose fibrosis and dysfunction

J Clin Invest. 2026 Jan 29:e192737. doi: 10.1172/JCI192737. Online ahead of print.ABSTRACTLipodystrophy syndromes are marked by loss of adipose tissue (AT), which leads to insulin resistance and metabolic syndrome development. We identified a heterozygous nonsense variant in early B cell factor 2 (E

M Maria C Foss-Freitas

Histopathological evaluation in post-mortem renal biopsies of patients with COVID-19 and comorbidities: a case-control study

Sao Paulo Med J. 2026 Jan 19;144(1):e2024376. doi: 10.1590/1516-3180.2024.0376.R1.13102025. eCollection 2026.ABSTRACTBACKGROUND: Acute kidney injury is one of the main systemic complications of severe coronavirus disease 2019 (COVID-19).OBJECTIVES: To examine histopathological changes in post-mortem

S Samya Hamad Mehanna