CONCLUSION: Compared with placebo, GLP-1 receptor agonists reduced AHI and BMI and improved mean SpO(2), and ranked highest for these outcomes in the SUCRA analysis. Comparisons between the active interventions, however, were largely non-significant and rested on indirect evidence, and the certainty
Front Physiol. 2026 Aug 17;17:1837224. doi: 10.3389/fphys.2026.1837224. eCollection 2026.ABSTRACTBACKGROUND: Gut microbiota plays a significant role in the occurrence and progression of multisystem disease. Previous studies have indicated that the intestinal microenvironment is closely linked to met
Ugeskr Laeger. 2026 Aug 17;188(34):V02260094. doi: 10.61409/V02260094.ABSTRACTThe maternal mortality rate in Denmark has decreased over the last few decades and is currently at its lowest with a stable rate of 3.3 per 100,000 live births (2012-2022). Nevertheless, some maternal deaths are still prev
Phytother Res. 2026 Sep 1. doi: 10.1002/ptr.70439. Online ahead of print.ABSTRACTIntracerebral hemorrhage (ICH) remains the most severe stroke subtype with high mortality and disability rates. Although apigenin has shown cerebroprotective potential in preclinical studies, its mechanism of action, pa
Zh Nevrol Psikhiatr Im S S Korsakova. 2026;126(8):110-119. doi: 10.17116/jnevro2026126081110.ABSTRACTThis report presents a case of acute severe poisoning with methadone and α-pyrrolidinovalerophenone in a 41-year-old male patient complicated by circulatory arrest. The poisoning occurred following t
Zh Nevrol Psikhiatr Im S S Korsakova. 2026;126(8):71-78. doi: 10.17116/jnevro202612608171.ABSTRACTOBJECTIVE: To identify factors associated with the progression of vascular moderate cognitive impairment (MCI) over 36 months, based on analyses of clinical, demographic, neuropsychological, laboratory,
J Biophotonics. 2026 Sep;19(9):e70353. doi: 10.1002/jbio.70353.ABSTRACTSIGNIFICANCE: This study leverages functional near-infrared spectroscopy (fNIRS) to elucidate optically derived cortical network signatures underlying combined sensory-motor interventions in stroke rehabilitation.AIM: To characte
Med J Aust. 2026 Sep;224(9):e70281. doi: 10.5694/mja2.70281.ABSTRACTI collapsed at the gym when a massive pulmonary embolism caused my heart to stop. Unbelievably I survived thanks to a clinical trial delivering an extracorporeal membrane oxygenation (ECMO) heart-lung bypass machine directly to me a
Biomater Sci. 2026 Sep 1. doi: 10.1039/d6bm00902f. Online ahead of print.ABSTRACTCardiovascular diseases continue to exhibit high global morbidity and mortality rates, driving urgent demand for the development of small-diameter (diameter < 6 mm) vascular grafts. Current small-diameter vascular graft
Cancer Epidemiol Biomarkers Prev. 2026 Sep 1;35(9):1490-1494. doi: 10.1158/1055-9965.EPI-25-1553.ABSTRACTPreviously considered primarily only in the context of dental diseases, the oral microbiome is now recognized as a contributor to a variety of systemic diseases, including cancer and cardiovascul
J Korean Med Sci. 2026 Aug 31;41(34):e218. doi: 10.3346/jkms.2026.41.e218.ABSTRACTBACKGROUND: Hip fractures in older adults often signal frailty and are associated with poor outcomes, including mortality and disability. Although a high burden of comorbidities is common, little is known about how the
Pulmonology. 2026 Dec;32(1):2719425. doi: 10.1080/25310429.2026.2719425. Epub 2026 Sep 1.ABSTRACTBACKGROUND: In the general population, supernormal lung function is associated with a lower risk of all-cause mortality.RESEARCH QUESTION: It remains unclear whether sleep-disordered breathing (SDB) affe
J Vet Sci. 2026 Jul 23. doi: 10.4142/jvs.26013. Online ahead of print.ABSTRACTIMPORTANCE: Endogenous Cushing's syndrome increases the risk of cardiac hypertrophy, dysfunction, and cardiovascular mortality. Given the high prevalence of hyperadrenocorticism (HAC) and myxomatous mitral valve disease (M
ACS Sens. 2026 Aug 26. doi: 10.1021/acssensors.6c01331. Online ahead of print.ABSTRACTCantilever-based biosensors provide a powerful approach for monitoring cardiomyocyte contractility, but conventional designs often exhibit baseline bending that compromises sensitivity and limits predictive accurac
J Musculoskelet Neuronal Interact. 2026 Sep 1;26(3):466-481.ABSTRACTHypermobile Ehlers-Danlos Syndrome (hEDS), a connective tissue disorder also known as Ehlers-Danlos Syndrome Type III or Ehlers-Danlos Syndrome Hypermobility Type, and Autism Spectrum Disorder (ASD), a neurodevelopmental disorder, p
Ann Transplant. 2026 Sep 1;31:e952503. doi: 10.12659/AOT.952503.ABSTRACTBACKGROUND The University of Wisconsin (UW) solution is the gold standard for kidney preservation. Quercetin (QE), a widely used flavonoid, possesses strong antioxidant, anti-inflammatory, and anti-apoptotic properties. Sucrose
Basic Clin Pharmacol Toxicol. 2026 Oct;139(4):e70299. doi: 10.1111/bcpt.70299.ABSTRACTVascular smooth muscle cells (VSMCs) are essential for maintaining arterial wall integrity, with their associated apoptosis critically involved in cardiovascular diseases. Intracellular chloride anion (Cl-) dysregu
Cancer. 2026 Sep 1;132(17):e70597. doi: 10.1002/cncr.70597.ABSTRACTG-protein-coupled receptor class C group 5 member D (GPRC5D) has emerged as a crucial immunotherapy target in relapsed/refractory multiple myeloma. Although the T-cell-engaging bispecific antibody talquetamab is currently the only ap
Am J Med Genet A. 2026 Aug 31. doi: 10.1002/ajmg.a.70254. Online ahead of print.ABSTRACTAchondroplasia is a skeletal dysplasia associated with severe short stature and multisystem complications due to a gain-of-function pathogenic variant in the FGFR3 gene. Vosoritide, a C-type natriuretic peptide a
Clin Cardiol. 2026 Sep;49(9):e70435. doi: 10.1002/clc.70435.ABSTRACTBACKGROUND: Transition zone (TZ) may serve as a potential substrate for atrial fibrillation (AF). This study aims to investigate the relationship of TZ burden with left atrial conduction velocity (LACV) and recurrence after circumfe
Medicine (Baltimore). 2026 Aug 28;105(35):e50462. doi: 10.1097/MD.0000000000050462.ABSTRACTBACKGROUND: Endovascular techniques and devices, including Woven EndoBridge (WEB) and stent-assisted coiling (SAC), expand the choice of therapies for complex aneurysms, while the evidence directly comparing t
Medicine (Baltimore). 2026 Aug 28;105(35):e50312. doi: 10.1097/MD.0000000000050312.ABSTRACTTo investigate the association of the geriatric nutritional risk index (GNRI) with all-cause and cardiovascular mortality among adults with rheumatoid arthritis (RA). Data were obtained from the National Healt
Medicine (Baltimore). 2026 Aug 28;105(35):e50420. doi: 10.1097/MD.0000000000050420.ABSTRACTRATIONALE: Percutaneous vertebroplasty (PVP) is widely used to treat vertebral compression fractures. Although it is generally considered a minimally invasive procedure, leakage and systemic migration of polym
Medicine (Baltimore). 2026 Aug 28;105(35):e50401. doi: 10.1097/MD.0000000000050401.ABSTRACTRATIONALE: According to the 2019 ERS/ESC guidelines, high-risk pulmonary embolism is defined as a case that presents with hemodynamic instability, obstructive shock, or cardiac arrest, and this condition has a
