Associations Between Smartwatch-Derived Measures and Cognitive Function: Findings From the Electronic Framingham Heart Study

J Am Heart Assoc. 2026 Aug 7:e049284. doi: 10.1161/JAHA.126.049284. Online ahead of print.ABSTRACTBACKGROUND: Daily heart rate (HR) and physical activity are biomarkers of cardiovascular disease. A smartwatch-derived metric, daily HR per step (DHRPS), has also been associated with cardiovascular dis

J Jie He

Keratin 17 Methyltransferasean14 Methylation Axis: A Novel Mechanism in Pulmonary Vascular Remodeling

J Am Heart Assoc. 2026 Aug 7:e045577. doi: 10.1161/JAHA.125.045577. Online ahead of print.ABSTRACTBACKGROUND: Pulmonary hypertension is a malignant cardiovascular disease characterized by pulmonary vascular remodeling, with core pathological features including pulmonary arterial wall thickening and

Y Yun Liu

A three-metabolite microbiota-associated signature for early risk stratification of gestational diabetes mellitus

Cardiovasc Diabetol. 2026 Aug 7;25(1):214. doi: 10.1186/s12933-026-03278-x.ABSTRACTBACKGROUND: Gestational diabetes mellitus (GDM) is associated with adverse pregnancy outcomes and long-term metabolic and cardiovascular risk. However, oral glucose tolerance testing at 24-28 gestational weeks limits

S Shuo Ma

Real-World Diagnostic Performance of Repeat Transthoracic Echocardiography Within a Multimodality Imaging Approach in Patients With Suspected Infective Endocarditis

J Am Heart Assoc. 2026 Aug 7:e050020. doi: 10.1161/JAHA.126.050020. Online ahead of print.ABSTRACTBACKGROUND: Echocardiography is central to the diagnosis of infective endocarditis (IE). Although guidelines recommend repeating echocardiography when clinical suspicion persists despite negative or inc

G Georgios Tzimas

Outcomes following major dysvascular lower limb amputation: an updated systematic review

BMC Cardiovasc Disord. 2026 Aug 6;26(1):674. doi: 10.1186/s12872-026-06377-5.ABSTRACTBACKGROUND: Adults with major lower limb amputation (LLA) due to dysvascular etiology often experience diverse health outcomes. However, the absence of standardized outcome reporting limits the ability to synthesize

S Shashank Ghai

Proteomic Mediators of Chronic Obstructive Pulmonary Disease Phenotypes and Coronary Artery Calcification Burden in Ever Smokers

J Am Heart Assoc. 2026 Aug 7:e046201. doi: 10.1161/JAHA.125.046201. Online ahead of print.ABSTRACTBACKGROUND: Chronic obstructive pulmonary disease (COPD) increases cardiovascular disease risk. Coronary artery calcification (CAC) predicts cardiovascular events and mortality in COPD. We hypothesized

A Asghar Abbasi

Dietary Approaches to Stop Hypertension Score Trajectories From Early to Middle Adulthood and Coronary Artery Calcium Progression in Middle Age

J Am Heart Assoc. 2026 Aug 7:e044564. doi: 10.1161/JAHA.125.044564. Online ahead of print.ABSTRACTBACKGROUND: The Dietary Approaches to Stop Hypertension (DASH) diet reduces blood pressure and cardiovascular disease risk, but its impact on later coronary artery calcium (CAC) progression is unclear.

X Xiong-Zhi Li

Utility of Prognostic Staging Systems in Transthyretin Amyloidosis Cardiomyopathy in the Era of Available Disease-Modifying Treatment

J Am Heart Assoc. 2026 Aug 7:e048585. doi: 10.1161/JAHA.125.048585. Online ahead of print.ABSTRACTBACKGROUND: Prognostic staging systems in transthyretin amyloid (ATTR) cardiomyopathy were developed before the introduction of disease-modifying treatment. We therefore evaluated contemporary risk stra

J Jens K Skov

Temporal comparison of clinical practice and outcomes in heart failure: the JROADHF and JROADHF-NEXT studies

Eur Heart J. 2026 Aug 8:ehag577. doi: 10.1093/eurheartj/ehag577. Online ahead of print.ABSTRACTBACKGROUND AND AIMS: Advances in therapeutics and interventions have enabled the comprehensive management of patients with heart failure (HF); however, real-world clinical practice remains poorly character

T Takeshi Tohyama

Link between alcohol consumption and myocardial infarction, stroke, and all-cause mortality among Swedish male automotive workers over 30 years

Scand J Prim Health Care. 2026 Dec;44(1):2712981. doi: 10.1080/02813432.2026.2712981. Epub 2026 Aug 7.ABSTRACTINTRODUCTION: The relationship between alcohol consumption and the incidence of myocardial infarction (MI), stroke and all-cause mortality exhibits significant regional variation.OBJECTIVE:

H Hanna Asp

Single-cell transcriptomic analysis of ferroptosis-associated cell populations in the progression of diabetic retinopathy

Int Ophthalmol. 2026 Aug 7;46(1):328. doi: 10.1007/s10792-026-04197-2.ABSTRACTBACKGROUND: Diabetic retinopathy (DR), a common microvascular complication of diabetes mellitus, has been associated with ferroptosis-related pathological mechanisms. Evidence indicates that ferroptosis may contribute to r

B Bing-Fen Duan

Concomitant Versus Staged Percutaneous Cervicocerebral Artery Revascularization with Coronary Artery Bypass Grafting

Cardiol Ther. 2026 Aug 7. doi: 10.1007/s40119-026-00465-5. Online ahead of print.ABSTRACTINTRODUCTION: The optimal strategy and timing for percutaneous cervicocerebral artery revascularization (PCAR) combined with coronary artery bypass grafting (CABG) remain uncertain in patients with severe caroti

J Jinwei Zhang

Targeting the non-coding RNA-PANoptosis axis: a novel frontier in disease diagnosis and therapy

Apoptosis. 2026 Aug 7;31(8):203. doi: 10.1007/s10495-026-02413-z.ABSTRACTProgrammed cell death represents a fundamental process in maintaining organismal homeostasis and responding to pathological challenges. The traditional view considered apoptosis, pyroptosis, and necroptosis as independent death

S Shaocong Wang

Long-term angiogenic and thromboinflammatory signatures in post-COVID-19 syndrome

Angiogenesis. 2026 Aug 7;29(4):55. doi: 10.1007/s10456-026-10075-3.ABSTRACTBACKGROUND: Post-COVID-19 syndrome is a major long-term sequela of severe SARS-CoV-2 infection, potentially involving persistent angiogenic and thromboinflammatory dysfunction, though long-term biomarker behavior remains uncl

A Arlette Araceli Mora Zetina

A multidimensional item response theory analysis of the Seattle Angina Questionnaire: measurement precision, differential item functioning, and potential for item reduction

Qual Life Res. 2026 Aug 7;35(9):257. doi: 10.1007/s11136-026-04368-9.ABSTRACTPURPOSE: The Seattle Angina Questionnaire (SAQ) is widely used to measure disease-specific health status in coronary artery disease, but its psychometric properties have not been evaluated using multidimensional item respon

H Henry U Michael

Metabolic reprogramming drives pancreatic β cell neogenesis from α cells

Nat Chem Biol. 2026 Aug 7. doi: 10.1038/s41589-026-02293-z. Online ahead of print.ABSTRACTLoss of functional β cells is a hallmark of diabetes, and restoring β cell mass remains a critical goal in the quest for a specific therapy. One potential strategy is to convert non-β cells in the islet, such a

Y Yufeng Zhang

Real-world assessment of adherence to inclisiran dosing schedule and LDL-C reduction in patients with hypercholesterolemia in Austria

J Clin Lipidol. 2026 Jul 20:S1933-2874(26)00455-1. doi: 10.1016/j.jacl.2026.07.025. Online ahead of print.ABSTRACTBACKGROUND: Inclisiran is a small interfering RNA that safely and effectively lowers low-density lipoprotein cholesterol (LDL-C) with twice-yearly dosing (after the initial and 3-month d

D Dieter Pätzold

Early versus delayed percutaneous coronary revascularization in patients with concomitant sepsis and non-ST elevation myocardial infarction

Cardiovasc Revasc Med. 2026 Aug 4:S1553-8389(26)00335-0. doi: 10.1016/j.carrev.2026.07.023. Online ahead of print.ABSTRACTBACKGROUND: The prognosis of patients with concomitant sepsis and severe coronary artery disease (CAD) who develop acute myocardial infarction (AMI) is poor. While percutaneous c

H Hafez Golzarian

Nutrition and cardiometabolic health in cystic fibrosis: Emerging evidence and research gaps

J Cyst Fibros. 2026 Aug 7:S1569-1993(26)03658-1. doi: 10.1016/j.jcf.2026.07.1983. Online ahead of print.ABSTRACTCardiometabolic risk is increasingly recognised as a significant and evolving health concern within the cystic fibrosis (CF) population. Although nutrition has long been central to CF mana

V Veronica Lynch

Association of incomplete device apposition with stroke recurrence after patent foramen ovale closure

Heart. 2026 Aug 7:heartjnl-2026-327956. doi: 10.1136/heartjnl-2026-327956. Online ahead of print.ABSTRACTBACKGROUND: The mechanisms underlying stroke recurrence after patent foramen ovale (PFO) closure for secondary prevention remain poorly understood. This study evaluated incomplete device appositi

C Chaowu Yan

Conversational artificial intelligence HeAlth supporT in Atrial Fibrillation Self-Management (CHAT-AF-S): rationale and randomised controlled trial design

BMJ Open. 2026 Aug 7;16(8):e120834. doi: 10.1136/bmjopen-2026-120834.ABSTRACTINTRODUCTION: Atrial fibrillation (AF), a common arrhythmia, is associated with impaired quality of life and increased stroke risk and mortality. Clinical guidelines recommend leveraging digital technologies to support pati

L Liliana Laranjo

STOP-RIO study: protocol for a randomised, controlled, open-label non-inferiority trial to test the safety of discontinuation of riociguat after balloon pulmonary angioplasty in chronic thromboembolic pulmonary hypertension

BMJ Open. 2026 Aug 7;16(8):e120820. doi: 10.1136/bmjopen-2026-120820.ABSTRACTINTRODUCTION: Balloon pulmonary angioplasty (BPA) improves haemodynamics and outcomes in patients with inoperable chronic thromboembolic pulmonary hypertension (CTEPH). Riociguat is frequently initiated before BPA to reduce

T Tamara Carina Rodenburg

Modeling cardiac electrical activity using cardiac organoids for drug screening

Pharmacol Res. 2026 Aug 7:108373. doi: 10.1016/j.phrs.2026.108373. Online ahead of print.ABSTRACTArrhythmia is one of the leading causes of mortality and lacks diagnostic and therapeutic options. Electrical activity at the cellular level is difficult to use as a basis for evaluating drug effects on

Q Qi Zhang

Novel murine models of hematopoietic-endothelial crosstalk in JAK2V617F-associated cardiovascular disease

Am J Pathol. 2026 Aug 7:S0002-9440(26)00227-0. doi: 10.1016/j.ajpath.2026.07.005. Online ahead of print.ABSTRACTCardiovascular disease (CVD) is a major complication of JAK2V617F-positive myeloproliferative neoplasms (MPNs), yet the mechanisms linking mutant hematopoiesis to CVD remain incompletely u

H Haoyi Zheng