Recent advances in polyendocrine metabolic ovarian syndrome, formerly polycystic ovary syndrome, with emphasis on endocrine and metabolic dysfunction and cardiovascular risk

J Intern Med. 2026 Aug 30. doi: 10.1111/joim.70156. Online ahead of print.ABSTRACTPolyendocrine metabolic ovarian syndrome (PMOS), previously known as polycystic ovary syndrome, affects 10%-13% of women of reproductive age and remains underdiagnosed despite its substantial health burden. The introdu

M Maria Forslund

ANGII Initiated HSF2 Trans-Activating HIF-1α Through Induction of ER Stress to Promote Cardiac Hypertrophy

Clin Exp Pharmacol Physiol. 2026 Sep;53(9):e70153. doi: 10.1111/1440-1681.70153.ABSTRACTHeat shock factor 2 (HSF2) and hypoxia-inducible factor 1α are activated by angiotensin II (ANGII) in cardiomyocytes. The endoplasmic reticulum (ER) stress plays a critical role in cardiac hypertrophy. Moreover,

R Renchuang Cao

Clinical factors associated with increase in serum transthyretin levels at 1-year with tafamidis in wild-type transthyretin amyloid cardiomyopathy

No abstractJ Cardiol. 2026 Aug 31:S0914-5087(26)00160-7. doi: 10.1016/j.jjcc.2026.07.022. Online ahead of print.NO ABSTRACTPMID:42669580 | DOI:10.1016/j.jjcc.2026.07.022

K Koji Yoshie

Phenotypic clustering and ABC pathway adherence in patients with atrial fibrillation at high risk of bleeding and stroke: Insights from three global registries

Eur J Intern Med. 2026 Aug 30:107160. doi: 10.1016/j.ejim.2026.107160. Online ahead of print.ABSTRACTBACKGROUND: Patients with atrial fibrillation (AF) who are at increased risk of both thrombotic and haemorrhagic events represent a heterogeneous and broad clinical entity, characterized by the prese

A Amir Askarinejad

Corrigendum to "Innovation and sustainability in immune-mediated diseases: An Italian multidisciplinary consensus across gastroenterology, dermatology, and rheumatology" [Digestive and Liver Disease 58 (2026) 1051-1060]

No abstractDig Liver Dis. 2026 Aug 30:S1590-8658(26)00876-5. doi: 10.1016/j.dld.2026.07.078. Online ahead of print.NO ABSTRACTPMID:42669572 | DOI:10.1016/j.dld.2026.07.078

F Franco Scaldaferri

Cardiovascular disease burden at cancer diagnosis: temporal trends in a national study from England

Eur Heart J. 2026 Aug 31:ehag626. doi: 10.1093/eurheartj/ehag626. Online ahead of print.ABSTRACTBACKGROUND AND AIMS: Advances in cancer care have improved survival, increasing the importance of comorbidities at diagnosis for longer-term outcomes. Pre-existing cardiovascular disease (CVD) can complic

A Ali A Alshahrani

Diabetic Retinopathy: From Molecular Mechanisms to Modern Therapy

Biochemistry (Mosc). 2026 Aug;91(8):1319-1340. doi: 10.1134/S000629792660105X.ABSTRACTDiabetic retinopathy (DR) remains one of the leading causes of vision loss. Its development is driven by complex interconnected pathophysiological mechanisms triggered by chronic hyperglycemia. Traditional diagnost

N Natalia G Shebardina

Complement-coagulation crosstalk in immunothrombosis

Rinsho Ketsueki. 2026;67(8):957-965. doi: 10.11406/rinketsu.67.957.ABSTRACTVenous thrombosis is initiated by endothelial cell activation triggered by reduced blood flow and venous stasis. Innate immune cells (neutrophils and monocytes) and platelets adhere to activated endothelial cells via P-select

T Toshiyuki Miyata

Cardiovascular-Kidney-Metabolic Syndrome Age Derived From Routine Health Checkup and Claims Data - Large-Scale Epidemiological Study

Circ J. 2026 Aug 28. doi: 10.1253/circj.CJ-26-0498. Online ahead of print.ABSTRACTBACKGROUND: The cardiovascular-kidney-metabolic (CKM) framework emphasizes the interplay of metabolic, renal, and cardiovascular abnormalities in cardiovascular disease risk. We aimed to develop a CKM syndrome age algo

Y Yuta Suzuki

Association of Pretreatment Hepatic Function Markers with Clazosentan-Associated Fluid Retention in Patients with Subarachnoid Hemorrhage

Biol Pharm Bull. 2026;49(8):1329-1333. doi: 10.1248/bpb.b26-00344.ABSTRACTClazosentan is used to prevent cerebral vasospasm after aneurysmal subarachnoid hemorrhage (SAH), but it is often associated with fluid retention-related adverse events. This retrospective study investigated the relationship b

K Kinuka Oguni

Management and Outcomes of Acute Coronary Syndrome during and after the COVID-19 Pandemic in Kurume City: A Multicenter Observational Study

Kurume Med J. 2026 Aug 31. doi: 10.2739/kurumemedj.MS7312009. Online ahead of print.ABSTRACTBACKGROUND: The impact of the coronavirus disease 2019 (COVID-19) pandemic on acute coronary syndrome (ACS) care has varied widely across regions. Data from stable regional healthcare systems remain limited,

M Masaharu Nakano

Impact of liver metastatic burden on prognosis of patients with pancreatic neuroendocrine tumor and liver metastases after radical resection

Zhonghua Wai Ke Za Zhi. 2026 Aug 31;64(10):1106-1114. doi: 10.3760/cma.j.cn112139-20260311-00096. Online ahead of print.ABSTRACTObjectives: To investigate the impact of liver metastatic burden on the prognosis of patients with pancreatic neuroendocrine tumor (pNET) complicated by synchronous liver m

L L Li

Vascular medicine in older adults - A call for structured cooperation to improve care

Vasa. 2026 Sep;55(5):320-321. doi: 10.1024/0301-1526/a001303.ABSTRACT The patient population treated by vascular medicine is becoming older, which goes along with an increasing number of patients presenting with frailty syndrome. The level of frailty determines the outcomes after vascular surgery or

G Gerald Kolb

Risk Assessment in MASLD and MetALD: Current Approaches and Future Directions

Clin Mol Hepatol. 2026 Aug 28. doi: 10.3350/cmh.2026.0398. Online ahead of print.ABSTRACTMetabolic dysfunction-associated steatotic liver disease (MASLD) and metabolic dysfunction and alcohol-related liver disease (MetALD) exist on a continuous spectrum in which fibrosis stage remains the dominant p

H Huapeng Lin

Cardio-renal protection of MRAs in kidney-transplanted diabetic patients

Pharmacol Res. 2026 Aug 30:108425. doi: 10.1016/j.phrs.2026.108425. Online ahead of print.ABSTRACTKidney transplantation (KT) remains the optimal treatment for kidney failure, improving survival and quality of life. However, long-term graft outcomes have plateaued, largely due to transplant CKD and

B Basset El Essawy

Clinical outcomes associated with recurrent compared to first-time myocardial infarction

Am Heart J. 2026 Aug 30:107592. doi: 10.1016/j.ahj.2026.107592. Online ahead of print.ABSTRACTBACKGROUND: Patients with recurrent myocardial infarction (MI) are a heterogenous group with high comorbidity burden, risk of complex coronary disease, and at risk of poor outcomes. However, contemporary co

D Daniel Mølager Christensen

Serial high-sensitivity troponin-T and risk of heart failure in individuals with suspected acute coronary syndrome

Int J Cardiol. 2026 Aug 30:134748. doi: 10.1016/j.ijcard.2026.134748. Online ahead of print.ABSTRACTAIMS: To investigate the association between serial high-sensitivity cardiac troponin-T (hs-TnT) concentrations and subsequent heart failure in individuals presenting with suspected acute coronary syn

P Philip Ahle Erichsen

Cardiovascular disease in pregnancy: physiology, global burden, risk stratification, and opportunities in care

Lancet. 2026 Aug 30:S0140-6736(26)01234-1. doi: 10.1016/S0140-6736(26)01234-1. Online ahead of print.ABSTRACTCardiovascular disease remains one of the leading causes of maternal mortality worldwide and a major driver of long-term morbidity. Yet, pregnancy-related cardiovascular complications are oft

T Tiffany L Brazile

Adverse pregnancy outcomes and long-term cardiovascular disease risk

Lancet. 2026 Aug 30:S0140-6736(26)01235-3. doi: 10.1016/S0140-6736(26)01235-3. Online ahead of print.ABSTRACTPregnancy provides a unique physiological stress test for the cardiovascular system, during which, adverse pregnancy outcomes (APOs) can unmask latent susceptibility to future disease. Common

M Maria A Pabón

Lipoprotein(a) and Atherosclerotic Cardiovascular Disease Among Adults Aged 20 to 100 Years

Circulation. 2026 Aug 30. doi: 10.1161/CIRCULATIONAHA.126.079412. Online ahead of print.ABSTRACTBACKGROUND: High lipoprotein(a) is considered a causal risk factor for atherosclerotic cardiovascular diseases (ASCVD); however, whether the association between lipoprotein(a) and ASCVD is different among

J Janeni Jeevanathan

Lipoprotein(a) and Atherosclerotic Cardiovascular Disease Risk: From Young to Older Adulthood

No abstractCirculation. 2026 Aug 30. doi: 10.1161/CIRCULATIONAHA.126.082984. Online ahead of print.NO ABSTRACTPMID:42669285 | DOI:10.1161/CIRCULATIONAHA.126.082984

S Sadiya S Khan

DiaActive protocol: A randomized controlled trial of cognitive-motor multicomponent exercise to reduce fall rate in older adults with diabetes

Diabet Med. 2026 Aug 30:e70461. doi: 10.1111/dme.70461. Online ahead of print.ABSTRACTINTRODUCTION: Older adults with diabetes have an increased risk of falls due to neuropathy, impaired bone health and cardiovascular disease, resulting in significant morbidity and mortality. Conventional fall-preve

A Aksayan Arunanthy Mahalingasivam

Brugada Syndrome in the Pediatric Population: Diagnostic Challenges and Clinical Outcome-Results of the German Multicenter Study COGIA

J Cardiovasc Electrophysiol. 2026 Aug 30. doi: 10.1111/jce.70484. Online ahead of print.ABSTRACTINTRODUCTION: Diagnosis and treatment of children and adolescents with suspected Brugada syndrome (BrS) is challenging. Aim of the study was to evaluate the applicability of current diagnostic criteria fo

L Lea Lippert

SerpinA3 is an Endogenous TGF-β Receptor Antagonist that Attenuates Cardiac Fibroblast Activation and Fibrotic Remodeling

Adv Sci (Weinh). 2026 Aug 30:e77379. doi: 10.1002/advs.77379. Online ahead of print.ABSTRACTBACKGROUND: Cardiac fibrosis is a central driver of adverse remodeling and heart failure (HF), yet effective antifibrotic therapies remain limited. SerpinA3, a member of the serine protease inhibitor family,

H Hui Wang