Nat Prod Bioprospect. 2026 Apr 23;16(1):57. doi: 10.1007/s13659-026-00629-9.ABSTRACTTwenty-eight prenylated acylphloroglucinols, including the new hypulatones C-F (1-4), have been isolated from the fruits of Hypericum patulum and structurally characterized. Compound 1 represents a rare meroterpenoid
Inflammation. 2026 Apr 22. doi: 10.1007/s10753-026-02507-5. Online ahead of print.ABSTRACTVascular calcification, a common complication of metabolic diseases such as diabetes and obesity, is closely associated with chronic inflammation and contributes to cardiovascular morbidity. The adipokine visfa
Pediatr Nephrol. 2026 Apr 23. doi: 10.1007/s00467-026-07283-w. Online ahead of print.ABSTRACTPatients with kidney disease face a markedly increased risk of developing cardiovascular disease (CVD) which manifests in multiple forms, including: left ventricular hypertrophy, heart failure, atheroscleros
Eur J Pediatr. 2026 Apr 22;185(5):289. doi: 10.1007/s00431-026-06967-7.ABSTRACTThe aim of this study is to map and synthesise the evidence on the scattered and heterogeneous reported prevalence of Bacillus Calmette-Guérin (BCG) scar reactivation (BCGitis) in Kawasaki disease (KD), examine clinical r
Pediatr Res. 2026 Apr 22. doi: 10.1038/s41390-026-05024-1. Online ahead of print.ABSTRACTBACKGROUND: Endovascular symptoms are among the most debilitating long COVID symptoms; however, underlying mechanisms are unclear. Children and young adults with long COVID, an understudied population, offer key
Cell Mol Immunol. 2026 Apr 22. doi: 10.1038/s41423-026-01417-8. Online ahead of print.ABSTRACTChanges in the immune microenvironment are key features of ischemic heart disease. In particular, excessive inflammatory responses driven by macrophages are the primary cause of myocardial injury, impaired
No abstractCardiovasc Interv Ther. 2026 Apr 22. doi: 10.1007/s12928-026-01268-0. Online ahead of print.NO ABSTRACTPMID:42020661 | DOI:10.1007/s12928-026-01268-0
No abstractCommunity Ment Health J. 2026 Apr 22. doi: 10.1007/s10597-026-01646-1. Online ahead of print.NO ABSTRACTPMID:42020633 | DOI:10.1007/s10597-026-01646-1
J Hum Hypertens. 2026 Apr 22. doi: 10.1038/s41371-026-01134-9. Online ahead of print.ABSTRACTHypertension is a major global health burden and a leading driver of cardiovascular disease, yet reliable blood-based biomarkers for early disease are still limited. We combined plasma proteomics with explai
Signal Transduct Target Ther. 2026 Apr 22;11(1):146. doi: 10.1038/s41392-026-02651-2.ABSTRACTVisual hallucination (VH) is a common nonmotor symptom of Parkinson's disease (PD). However, the lack of reliable animal models and quantitative assessment tools poses significant challenges for mechanism an
Ren Fail. 2026 Dec;48(1):2646035. doi: 10.1080/0886022X.2026.2646035. Epub 2026 Apr 22.ABSTRACTIndividual cardiometabolic risk factors (CMRFs) are contributors to reduced kidney function, their cumulative impact and population-specific differences remain unclear. This cross-sectional study investiga
Heart Lung Circ. 2026 Apr 21:S1443-9506(25)01744-5. doi: 10.1016/j.hlc.2025.11.017. Online ahead of print.ABSTRACTBACKGROUND: Increased lipoprotein(a) (Lp[a]) is a genetically determined causal risk factor for atherosclerotic cardiovascular disease (ASCVD). Historically, Lp(a) testing has been uncom
Heart Lung Circ. 2026 Apr 21:S1443-9506(26)00053-3. doi: 10.1016/j.hlc.2026.01.009. Online ahead of print.ABSTRACTBACKGROUND: The incidence of aortic stenosis (AS) in the older adult population in Western countries is increasing. When left untreated, AS progresses to clinical heart failure, reduced
Clin Exp Pharmacol Physiol. 2026 May;53(5):e70121. doi: 10.1111/1440-1681.70121.ABSTRACTOBJECTIVE: Acute myocardial infarction (AMI) remains the leading global cause of mortality. This study explored the mechanism by which ginsenoside Rg1 (Rg1) ameliorates cardiac function and ventricular remodellin
Zhonghua Liu Xing Bing Xue Za Zhi. 2026 Apr 10;47(4):625-632. doi: 10.3760/cma.j.cn112338-20250711-00483.ABSTRACTObjective: To explore the correlation between exposure to perfluoroalkyl substances (PFAS) and the risk of cardiovascular disease, and investigate the mediating role of uric acid and the
Zhonghua Liu Xing Bing Xue Za Zhi. 2026 Apr 10;47(4):586-594. doi: 10.3760/cma.j.cn112338-20250916-00652.ABSTRACTObjective: To investigate the associations between multiple non-invasive atherosclerotic indicators and the risk of cardiovascular disease (CVD) outcomes in Chinese adults. Methods: Based
Zhonghua Liu Xing Bing Xue Za Zhi. 2026 Apr 10;47(4):579-585. doi: 10.3760/cma.j.cn112338-20251205-00871.ABSTRACTObjective: To evaluate the associations of waist-to-hip ratio (WHR) and BMI-adjusted WHR (WHRadjBMI) with all-cause, cardiovascular disease (CVD)-attributed, and non-CVD-attributed mortal
Open Heart. 2026 Apr 22;13(1):e003971. doi: 10.1136/openhrt-2026-003971.ABSTRACTOBJECTIVE: Syndromic conditions are frequently associated with congenital heart disease (CHD). Their distribution, recognition and prognostic impact in adults with CHD (ACHD) remain poorly characterised due to limited as
BMJ Open. 2026 Apr 22;16(4):e117846. doi: 10.1136/bmjopen-2026-117846.ABSTRACTINTRODUCTION: Sepsis is a global health priority with nearly 50 million cases annually. Cardiovascular dysfunction is common, frequently manifesting as hypotension that persists despite fluid resuscitation. Most affected p
BMJ Open. 2026 Apr 22;16(4):e115162. doi: 10.1136/bmjopen-2025-115162.ABSTRACTOBJECTIVES: Data on long-term outcomes after surgical repair of pulmonary valve stenosis are limited. This study evaluated survival, clinical outcomes and quality of life (QoL) after surgery during childhood.METHODS: Singl
BMJ Case Rep. 2026 Apr 22;19(4):e270353. doi: 10.1136/bcr-2025-270353.ABSTRACTWe report a case of radiologically confirmed large vessel vasculitis (LVV) in a woman in her 70s undergoing neoadjuvant FOLFIRINOX (folinic acid, 5-fluorouracil, irinotecan, oxaliplatin) chemotherapy for borderline resecta
Lancet Public Health. 2026 May;11(5):e293-e305. doi: 10.1016/S2468-2667(26)00048-4.ABSTRACTBACKGROUND: The increasing prevalence of most non-communicable diseases in Italy represents a major public health challenge, largely influenced by modifiable risk factors. This study aims to analyse time trend
Lancet Public Health. 2026 May;11(5):e280-e292. doi: 10.1016/S2468-2667(26)00052-6.ABSTRACTBACKGROUND: Incidence of multiple long-term conditions (MLTCs), or multimorbidity, is inconsistently defined and infrequently reported at whole-population level. We aimed to measure the MLTC incidence and prog
Radiol Clin North Am. 2026 May;64(3):605-621. doi: 10.1016/j.rcl.2026.01.013. Epub 2026 Feb 26.ABSTRACTThe growing volume of clinical imaging and the emergence of artificial intelligence technologies present a unique opportunity to extract additional value from existing imaging data that would other
