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Cardiovascular disease

Development and Validation of NICVD-NQ Score for Predicting Short-Term Outcomes After Primary PCI

Catheter Cardiovasc Interv. 2026 May 13. doi: 10.1002/ccd.70657. Online ahead of print.ABSTRACTBACKGROUND: Despite advances in primary percutaneous coronary intervention (PCI), patients with ST-elevation myocardial infarction (STEMI) continue to experience major adverse cardiovascular events (MACE)

R Rajesh Kumar

In Response to "Is low lean body mass a risk factor for hypertension?"

No abstractHypertens Res. 2026 May 13. doi: 10.1038/s41440-026-02670-0. Online ahead of print.NO ABSTRACTPMID:42129574 | DOI:10.1038/s41440-026-02670-0

T Tatsuhiko Azegami

Development and validation of a versatile foundation model for cine cardiac magnetic resonance image analysis

Commun Med (Lond). 2026 May 13. doi: 10.1038/s43856-026-01636-0. Online ahead of print.ABSTRACTBACKGROUND: Cardiac magnetic resonance imaging is central to cardiovascular diagnosis and management, yet extracting key clinical measurements remains time-consuming, subjective, and of limited reproducibi

Y Yunguan Fu

Shared decision-making for preventive sports cardiology in youth with heart disease: a pilot study

Pediatr Res. 2026 May 7. doi: 10.1038/s41390-026-05012-5. Online ahead of print.ABSTRACTBACKGROUND: Many youth with heart disease remain inactive despite the recognized benefits of physical activity. Shared decision-making (SDM) between patients, families, and care teams has been proposed to support

M Manon Petrault

Harnessing hybrid stacking ensemble learning for accurate pulmonary embolism diagnosis using tabular clinical data

Sci Rep. 2026 May 13;16(1):15051. doi: 10.1038/s41598-026-49331-3.ABSTRACTPulmonary Embolism (PE) is a serious condition that can be life-threatening if not diagnosed promptly as timely clinical decisions are critical. This research aims to present a hybrid stacking ensemble (HSE) framework for PE p

A Abeer Abdelhamid

A deep learning ECG model for identification and localization of occlusion myocardial infarction

Nat Commun. 2026 May 13;17(1):4336. doi: 10.1038/s41467-026-73023-1.ABSTRACTRapid identification and localization of an acute coronary occlusion are vital to prevent myocardial damage, yet reliance on ST-segment ECG criteria misses many acute occlusion myocardial infarctions (OMI) and triggers unnec

S Stefan Gustafsson

MeCP2 Governs maternal hyperandrogenism-induced cortical defects and behavioral alterations via noncanonical AR-dependent regulation of Mef2c

Nat Commun. 2026 May 13;17(1):4225. doi: 10.1038/s41467-026-72942-3.ABSTRACTElevated prenatal androgen levels have been associated with an increased incidence of several neurodevelopmental conditions in offspring. However, the underlying mechanisms remain poorly understood. Here we showed that eleva

Y Yu-Meng Wang

ABL kinases regulate FGF signaling independent of CRK phosphorylation to prevent Peters anomaly type II

Nat Commun. 2026 May 13. doi: 10.1038/s41467-026-72489-3. Online ahead of print.ABSTRACTPeters anomaly is an anterior segment dysgenesis and a leading cause of congenital corneal opacity. Here, we show that loss of ABL kinases restores lens induction in the absence of FGF signaling but induces Peter

H Hao Wu

Clinically-applicable prediction of hospital stay and patient similarity retrieval in paediatric cardiology using machine learning

Nat Commun. 2026 May 13. doi: 10.1038/s41467-026-73021-3. Online ahead of print.ABSTRACTPaediatric cardiology presents challenges due to the rarity and complexity of conditions like congenital heart disease. Using retrospective electronic healthcare records from 1,522 Great Ormond Street Hospital ca

L Louise Rigny

Shining Light on Dysautonomia: The Role of Vitamin D in Cardiac Autonomic Regulation

Curr Nutr Rep. 2026 May 14;15(1):46. doi: 10.1007/s13668-026-00769-x.ABSTRACTPURPOSE OF REVIEW: Traditionally recognized for its role in calcium homeostasis and bone metabolism, vitamin D is increasingly acknowledged for its broader physiological effects, particularly in cardiovascular health. One a

H Huai Heng Loh

Volumetric analysis of bone resorption rate during lateral sinus lift: a retrospective study

Int J Implant Dent. 2026 May 13. doi: 10.1186/s40729-026-00691-5. Online ahead of print.ABSTRACTOBJECTIVE: To evaluate 1-year bone resorption after lateral sinus lift and assess the influence of contributing factors (Schneiderian membrane perforation, sinus anatomy, and surgical variables).METHODS:

T Thouveny Gabriel

Early versus late anticoagulation on outcomes in large hemispheric infarction: a propensity score-matched analysis

J Neurol. 2026 May 13;273(6):311. doi: 10.1007/s00415-026-13847-5.ABSTRACTOBJECTIVE: The optimal timing of anticoagulation initiation in patients with large hemispheric infarction (LHI) remains uncertain, particularly the trade-off between thromboembolism and hemorrhagic transformation risk. This st

Y Yanan Lin

Clinical profiles of MRI-negative ischemia and stroke mimics after thrombolysis: insights into diagnostic uncertainty in acute ischemic stroke care

J Neurol. 2026 May 13;273(6):310. doi: 10.1007/s00415-026-13845-7.ABSTRACTBACKGROUND: Intravenous thrombolysis (IVT) for suspected acute ischemic stroke is initiated before definitive imaging confirmation, resulting in treatment of patients later classified as MRI confirmed infarction (MRI +), MRI n

A Aysha Jadran

Crosstalk between the monocytes and coagulation factor VⅡa aggravates the inflammation in patients with CAD

Immunol Res. 2026 May 14;74(1):55. doi: 10.1007/s12026-026-09784-0.ABSTRACTThe underlying proinflammatory mechanism of coagulation factor VⅡ in coronary artery disease (CAD) remains unclear. According to the inclusion criteria, 24 non-CAD subjects and 24 patients with CAD were enrolled. The expressi

B Baofu Wang

Pediatric cerebral aneurysms: long-term outcomes from a single-center case series and a narrative review of the contemporary literature

Childs Nerv Syst. 2026 May 14;42(1):219. doi: 10.1007/s00381-026-07320-x.ABSTRACTBACKGROUND: Pediatric intracranial aneurysms (PIAs) are rare and present with distinct clinical and morphological features compared to adult cases. They are often associated with congenital anomalies, larger size, and u

M Majed A Alghamdi

Validation of circulating miR-323a-3p and miR-625-3p to classify hypertrophic cardiomyopathy in Friedreich's ataxia

Sci Rep. 2026 May 13;16(1):15056. doi: 10.1038/s41598-026-50975-4.ABSTRACTFriedreich's ataxia (FRDA) is an inherited neurodegenerative disorder frequently complicated by hypertrophic cardiomyopathy (HCM), a major cause of morbidity and mortality in these patients. Conventional protein biomarkers, su

J José Santiago Ibáñez-Cabellos

Fibrin-associated large B-cell lymphoma confined to a left atrial myxoma showing durable remission after surgical resection alone

Rinsho Ketsueki. 2026;67(4):316-320. doi: 10.11406/rinketsu.67.316.ABSTRACTFibrin-associated large B-cell lymphoma is an extremely rare subtype of LBCL, characterized by distinctive pathological findings and symptoms, and is generally considered to follow an indolent clinical course. Here we report

N Natsumi Sakai

Clinical outcomes of idecabtagene vicleucel therapy for relapsed/refractory multiple myeloma: a single-center retrospective analysis

Rinsho Ketsueki. 2026;67(4):289-298. doi: 10.11406/rinketsu.67.289.ABSTRACTIdecabtagene vicleucel (ide-cel) is effective for relapsed/refractory multiple myeloma (RRMM), but real-world data in Japan are limited. We retrospectively analyzed 11 patients with RRMM who received ide-cel at our institutio

K Kairi Kojo

Impact of Deprescribing Medications on Muscle Strength and Muscle Mass in Older Patients with Sarcopenia after Stroke

Biol Pharm Bull. 2026;49(5):770-777. doi: 10.1248/bpb.b25-00748.ABSTRACTPolypharmacy is prevalent among older adults with sarcopenia and may negatively impact clinical outcomes. Although sarcopenia is associated with polypharmacy, the effect of deprescribing on muscle health in hospitalized patients

E Eiji Kose

FEV1 is a major prognostic factor in diverse Heart Failure populations: findings from a Global Heart Failure registry

ESC Heart Fail. 2026 May 13:xvag128. doi: 10.1093/eschf/xvag128. Online ahead of print.ABSTRACTAIMS: Pulmonary abnormalities are commonly reported in heart failure (HF) and may have prognostic implication. Current evidence is limited to high-income countries. We examined the relationship between for

M MyLinh Duong

Anthocyanin-rich dried fruit consumption increases polyphenol excretion and lowers plasma uric acid in coronary artery disease: a randomized trial

Nutr Metab Cardiovasc Dis. 2026 Apr 2:104727. doi: 10.1016/j.numecd.2026.104727. Online ahead of print.ABSTRACTBACKGROUND AND AIM: It has been suggested that foods abundant in anthocyanins may offer a range of health benefits. This study aimed to assess the effects of anthocyanin-rich dried fruits o

S Sogand Tavakoli

Temporal trends in hyperlipidemia among adults with diabetes mellitus, 1999-2024: insights from the CDC WONDER Database

Nutr Metab Cardiovasc Dis. 2026 Apr 28:104771. doi: 10.1016/j.numecd.2026.104771. Online ahead of print.ABSTRACTBACKGROUND AND AIMS: Hyperlipidemia and diabetes mellitus (DM) often occur together, increasing the risk of cardiovascular disease and premature death. While both conditions have been stud

S Saifullah Khan

Frailty and Coronary Artery Disease: Proposed Pathophysiology and A Complex Interaction Influencing Management and Outcomes in Older Adults

Heart Lung Circ. 2026 May 13:S1443-9506(26)00364-1. doi: 10.1016/j.hlc.2026.05.002. Online ahead of print.ABSTRACTCoronary artery disease (CAD) and frailty frequently coexist in older adults and represent a growing clinical challenge in the context of an ageing population. Frailty, a multidimensiona

A Ammar Albayati

Prospective use of genomics in the evaluation of sudden cardiac death: results from a national health service population pathway

EBioMedicine. 2026 May 13:106266. doi: 10.1016/j.ebiom.2026.106266. Online ahead of print.ABSTRACTBACKGROUND: Sudden cardiac death (SCD) is a major cause of premature and potentially avoidable mortality. Determining whether a SCD was caused by an inherited cardiac condition (ICC) enables identificat

C Cian Wade