Linezolid is effective against multidrug-resistant TB (MDR-TB) but is frequently associated with adverse events that limit long-term use. However, data on the clinical outcomes following linezolid-related adverse events among patients with MDR-TB remain limited.This retrospective multicentre study i
Neth Heart J. 2025 Dec 18. doi: 10.1007/s12471-025-02011-9. Online ahead of print.ABSTRACTThis review evaluates the 2023 European Society of Cardiology (ESC) guidelines for the management of infective endocarditis (IE) and offers insights into topics particularly relevant to clinical practice in the
Neth Heart J. 2025 Dec 18. doi: 10.1007/s12471-025-02010-w. Online ahead of print.ABSTRACTThis review evaluates the 2023 European Society of Cardiology (ESC) guidelines for the management of infective endocarditis (IE) and offers insights into topics particularly relevant to clinical practice in the
Cardiovasc Drugs Ther. 2025 Dec 18. doi: 10.1007/s10557-025-07828-5. Online ahead of print.ABSTRACTCardiovascular disease (CVD) remains a leading cause of morbidity and mortality globally, accounting for nearly one-third of deaths worldwide. Intercellular communication between cardiomyocytes and non
Tidsskr Nor Laegeforen. 2025 Nov 13;145(15). doi: 10.4045/tidsskr.25.0374. Print 2025 Dec 16.ABSTRACTBACKGROUND: Non-invasive prenatal testing (NIPT) is a genetic analysis based on a blood test from a pregnant woman, which can assess the likelihood of the fetus having trisomy 13, 18 or 21. Early ult
Tidsskr Nor Laegeforen. 2025 Nov 20;145(15). doi: 10.4045/tidsskr.25.0186. Print 2025 Dec 16.ABSTRACTBACKGROUND: Secondary preventive treatment for patients with known coronary artery disease reduces the risk of new cardiovascular events. We studied the extent to which patients with known coronary a
Tidsskr Nor Laegeforen. 2025 Dec 15;145(15). doi: 10.4045/tidsskr.25.0261. Print 2025 Dec 16.ABSTRACTBACKGROUND: Early repolarisation syndrome (ERS) is a rare but important cause of sudden cardiac death in otherwise healthy individuals. It is characterised by early repolarisation changes on the elec
Asian Cardiovasc Thorac Ann. 2025 Dec 18:2184923251408874. doi: 10.1177/02184923251408874. Online ahead of print.ABSTRACTIt is desirable to preserve the pulmonary valve annulus as much as possible, but the decision to preserve the annulus should be made by taking into account not only the annulus di
Cancer Immunol Immunother. 2025 Dec 18;75(1):9. doi: 10.1007/s00262-025-04247-1.ABSTRACTBACKGROUND: Chimeric antigen receptor T cell (CAR-T) therapy achieves high remission rates in lymphoid malignancies, but its long-term efficacy is limited by poor persistence and T cell exhaustion. Pomalidomide,
Cardiovasc Toxicol. 2025 Dec 18;26(1):2. doi: 10.1007/s12012-025-10074-8.ABSTRACTHigh-density lipoproteins (HDLs) are endogenous nanoparticles critical for cholesterol transport, vascular protection, and immune modulation. Cardiovascular disease (CVD) often induces dysfunctional HDL, driving the eme
High Blood Press Cardiovasc Prev. 2025 Dec 18. doi: 10.1007/s40292-025-00771-4. Online ahead of print.ABSTRACTINTRODUCTION: Chronic kidney disease (CKD) is associated with dyslipidaemia. Renal dysfunction changes the level, composition and quality of blood lipids in favor of a more atherogenic profi
Curr Atheroscler Rep. 2025 Dec 18;28(1):1. doi: 10.1007/s11883-025-01371-2.ABSTRACTPURPOSE OF REVIEW: This review synthesizes and discusses evidence from metagenomics, metabolomics, and proteomics on gut microbiome alterations in atherosclerotic cardiovascular disease (ACVD), with carotid atheroscle
Inflammopharmacology. 2025 Dec 18. doi: 10.1007/s10787-025-02089-y. Online ahead of print.ABSTRACTCitrus peels, obtained from fruits belonging to the genus Citrus, of family Rutaceae, represents a major agro-industrial waste with significant nutritional and health benefits. These are composed of a v
Neurosurg Rev. 2025 Dec 18;49(1):81. doi: 10.1007/s10143-025-04023-w.ABSTRACTInterethnic differences in natural transdural collaterals-an angiographical hallmark of Moyamoya disease (MMD)-may reflect the genetic and pathophysiological mechanisms underlying ethnic disparities. However, international
Eur J Trauma Emerg Surg. 2025 Dec 18;51(1):363. doi: 10.1007/s00068-025-03042-y.ABSTRACTPURPOSE: Post-traumatic pulmonary embolism (PE) may develop directly in the lungs, termed "de novo" pulmonary embolism (DNPE). Severe chest trauma has been identified as a potential risk factor for DNPE due to lo
Immunol Res. 2025 Dec 18;73(1):174. doi: 10.1007/s12026-025-09707-5.ABSTRACTBACKGROUND: Cardiovascular-kidney-metabolic (CKM) syndrome is a major public health concern associated with increased mortality. Inflammation plays a critical role in CKM progression and outcomes. This study investigates the
Cardiovasc Toxicol. 2025 Dec 18;26(1):3. doi: 10.1007/s12012-025-10080-w.ABSTRACTConsidering the global prevalence of diabetes, diabetic cardiomyopathy (DCM), as a significant diabetes complication, remains a major human challenge; while previous studies have identified ferroptosis as an important u
Curr Neurol Neurosci Rep. 2025 Dec 18;26(1):1. doi: 10.1007/s11910-025-01473-z.ABSTRACTPURPOSE OF REVIEW: To summarise contemporary strategies to detect atrial fibrillation (AF) after stroke/transient ischemic attack (TIA) with emphasis on implantable loop recorders (ILRs), evaluate who should recei
Herz. 2025 Dec 18. doi: 10.1007/s00059-025-05358-2. Online ahead of print.ABSTRACTThe 2025 European Society of Cardiology (ESC) Guidelines on cardiovascular disease in pregnancy represents the second revision of the guideline versions published in 2011 and 2018. The new version aims to incorporate t
Eur J Prev Cardiol. 2025 Dec 18:zwaf715. doi: 10.1093/eurjpc/zwaf715. Online ahead of print.ABSTRACTAIMS: The prevalence of ventricular fibrosis and its association with ventricular arrhythmias (VAs) and reduced ventricular systolic function in endurance athletes remains unclear.METHODS AND RESULTS:
Clin Sci (Lond). 2025 Dec 18;139(24):CS20257213. doi: 10.1042/CS20257213.ABSTRACTLauryl gallate (LG, E312) is an antioxidant with hydrophobic properties that contribute to its activity by increasing affinity for membranes and acting on the lipid phase transition and likely the lateral membrane organ
Clin Exp Rheumatol. 2025 Dec;43(12):2036-2044. doi: 10.55563/clinexprheumatol/is2acv. Epub 2025 Dec 4.ABSTRACTOBJECTIVES: The phenotype of Sjögren's disease (SjD) may be influenced by several variables. Among these, the role of patient geolocation has been poorly explored. The study compared epidemi
NEJM Evid. 2025 Dec 18:EVIDoa2500074. doi: 10.1056/EVIDoa2500074. Online ahead of print.ABSTRACTBACKGROUND: Vaso-occlusive crisis (VOC) is the most common manifestation of sickle cell disease, and acute chest syndrome (ACS) is a frequent complication with a substantial risk of death. The aim of this
Radiol Cardiothorac Imaging. 2025 Dec;7(6):e250082. doi: 10.1148/ryct.250082.ABSTRACTPurpose To assess the diagnostic accuracy of 12-lead electrocardiography (ECG) in detecting, quantifying, and localizing prior myocardial infarction (pMIs) using cardiac MRI as the reference standard. Materials and
