Advanced microfluidic and 3D cell culture platforms for modeling vascularization in diabetic foot ulcers: A systematic review of translational challenges and perspectives

PLoS One. 2026 Apr 6;21(4):e0328278. doi: 10.1371/journal.pone.0328278. eCollection 2026.ABSTRACTThe healing process of diabetic foot ulcers (DFUs) presents a slow pattern with an increased risk of infections, ischemia, and thrombosis correlated with high levels of reactive oxygen species production

A Ana Karoline Almeida da Silva

A Hypoxia-reoxygenation Injury Model in Self-assembling Human Cardioids

J Vis Exp. 2026 Mar 17;(229). doi: 10.3791/70310.ABSTRACTWithout rapid revascularization, ischemic heart disease leads to irreversible loss of cardiomyocytes, scar formation, and decreased cardiac function. The ability to model hypoxia-reoxygenation injuries and evaluate potential therapeutic interv

L Lauren E Parker

Changes in the use of vitamin K antagonists and direct oral anticoagulants and impact on the incidence of oral anticoagulation-related intracerebral hemorrhage: population-wide prescription patterns in two 5-year cohorts

Ann Med. 2026 Dec;58(1):2652115. doi: 10.1080/07853890.2026.2652115. Epub 2026 Apr 6.ABSTRACTBACKGROUND: We investigated population-wide changes in prescriptions of oral anticoagulants (OAC) (vitamin K antagonists [VKA]) compared to direct oral anticoagulants (DOAC) and whether these translated into

L Liisa Tomppo

Ventricular Tachycardia as the Initial Presentation of Tuberculous Myocarditis

JACC Case Rep. 2026 Apr 6:107613. doi: 10.1016/j.jaccas.2026.107613. Online ahead of print.ABSTRACTBACKGROUND: Myocardial involvement in tuberculosis is exceptionally rare and may closely mimic cardiac sarcoidosis, particularly when presenting with ventricular arrhythmias.CASE SUMMARY: A 47-year-old

A Arnau Subira-Ingla