Environ Int. 2026 Apr 19;211:110271. doi: 10.1016/j.envint.2026.110271. Online ahead of print.ABSTRACTBACKGROUND: The urban heat island (UHI) effect is increasingly recognized as an environmental risk factor for human health, yet its association with type 2 diabetes (T2D) and underlying mechanisms r
Nutrition. 2026 Mar 8;148:113183. doi: 10.1016/j.nut.2026.113183. Online ahead of print.ABSTRACTCONTEXT: The Mediterranean diet (MD) is widely recognized for its health benefits and increasing relevance in health system planning and dietary policy. Understanding the costs and cost-effectiveness of M
Circ Heart Fail. 2026 Apr 24. doi: 10.1161/CIRCHEARTFAILURE.125.014049. Online ahead of print.ABSTRACTBackground: Circulatory support escalation is often required during cardiogenic shock (CS) treatment. Currently, no large-scale data is available to inform how escalation strategies integrate in con
Neurology. 2026 May 12;106(9):e214803. doi: 10.1212/WNL.0000000000214803. Epub 2026 Apr 24.ABSTRACTBACKGROUND AND OBJECTIVES: Cerebral small vessel disease (SVD) is the most common vascular contributor to dementia. SVD markers often coexist, contributing to difficulty assessing their independent con
JMIR Med Inform. 2026 Apr 24;14:e83127. doi: 10.2196/83127.ABSTRACTBACKGROUND: Artificial intelligence-augmented electrocardiogram (AI-ECG) models for detecting left ventricular systolic dysfunction (LVSD) often exhibit degraded performance in patients with comorbidities.OBJECTIVE: This study aimed
Nutr Rev. 2026 Apr 24:nuag058. doi: 10.1093/nutrit/nuag058. Online ahead of print.ABSTRACTCONTEXT: Increasing our intake of plant-based protein may help improve both population and planetary health. A systematic synthesis of randomized controlled trials is needed to clarify evidence on the effects o
J Clin Invest. 2026 Apr 24:e204602. doi: 10.1172/JCI204602. Online ahead of print.ABSTRACTThe liver plays a critical role in lipid homeostasis, where lipids are either secreted as very-low-density lipoproteins (VLDL) or stored in lipid droplets (LDs). However, the regulatory mechanisms governing the
Sci Adv. 2026 Apr 24;12(17):eaed2780. doi: 10.1126/sciadv.aed2780. Epub 2026 Apr 24.ABSTRACTWhether a pharmacological strategy can replicate the broad improvement of human cardiometabolic health associated with brown fat (BAT) remains an active area of investigation. Here, we show that adipokine Adi
Echocardiography. 2026 May;43(5):e70473. doi: 10.1111/echo.70473.ABSTRACTWe present the case of a 52-year-old male with severe primary mitral regurgitation, with biventricular dilatation and systolic impairment. Pre-operative exercise stress echocardiography revealed absence of left and right ventri
PLoS One. 2026 Apr 24;21(4):e0335834. doi: 10.1371/journal.pone.0335834. eCollection 2026.ABSTRACTBACKGROUND: This cross-sectional study aimed to investigate whether vitamin B intake (thiamine, riboflavin, niacin) influences different hypertension subtypes and which subtype exhibits a more profound
Echocardiography. 2026 May;43(5):e70464. doi: 10.1111/echo.70464.ABSTRACTBACKGROUND: Stroke and atrial fibrillation are frequent manifestations of left atrial (LA) myopathy in patients with end-stage kidney disease (ESKD). However, the natural history of LA dysfunction and its reversibility followin
PLoS One. 2026 Apr 24;21(4):e0348133. doi: 10.1371/journal.pone.0348133. eCollection 2026.ABSTRACTPURPOSE: COVID-19 infection has been associated with cardiovascular complications, including new-onset atrial fibrillation/flutter (NOAF). However, the potential protective effect of COVID-19 vaccinatio
PLoS One. 2026 Apr 24;21(4):e0348030. doi: 10.1371/journal.pone.0348030. eCollection 2026.ABSTRACTBACKGROUND: Low-intensity focused ultrasound (LIFU) is a non-invasive neuromodulation technique with high spatial precision and the ability to reach deeper brain regions, offering potential advantages f
PLoS One. 2026 Apr 24;21(4):e0347666. doi: 10.1371/journal.pone.0347666. eCollection 2026.ABSTRACTIn addition to aortic manifestations, Marfan syndrome can affect retinal vessels. Our aim was to evaluate retinal circulation, and its correlation with genotype and cardiovascular manifestation identify
PLoS One. 2026 Apr 24;21(4):e0347835. doi: 10.1371/journal.pone.0347835. eCollection 2026.ABSTRACTChronic kidney disease progression involves phenotypic changes in tubular epithelial cells, and recent studies have highlighted the relationship between such pro-fibrotic phenotypes and cell cycle arres
PLoS Genet. 2026 Apr 24;22(4):e1012120. doi: 10.1371/journal.pgen.1012120. eCollection 2026 Apr.ABSTRACTEmerging evidence reveals the pivotal involvement of mitochondrial metabolic dysregulation in glioblastoma (GBM) pathogenesis, considering mitochondrial metabolism as a potential therapeutic targe
No abstractAm J Physiol Lung Cell Mol Physiol. 2026 Apr 24. doi: 10.1152/ajplung.00016.2026. Online ahead of print.NO ABSTRACTPMID:42030252 | DOI:10.1152/ajplung.00016.2026
No abstractAm J Physiol Heart Circ Physiol. 2026 Apr 24. doi: 10.1152/ajpheart.00315.2026. Online ahead of print.NO ABSTRACTPMID:42030249 | DOI:10.1152/ajpheart.00315.2026
Am J Physiol Heart Circ Physiol. 2026 Apr 24. doi: 10.1152/ajpheart.00047.2026. Online ahead of print.ABSTRACTAlzheimer disease (AD) is a growing health problem characterized by neurocognitive and cardiovascular dysfunction. Although parental obesity programs adverse cardiometabolic complications, i
Am J Physiol Lung Cell Mol Physiol. 2026 Apr 24. doi: 10.1152/ajplung.00299.2025. Online ahead of print.ABSTRACTPulmonary arterial hypertension (PAH) is a severe disease affecting the pulmonary arteries, causing increased blood pressure due to narrowing of the pulmonary artery lumen. Aberrant prolif
Am J Physiol Lung Cell Mol Physiol. 2026 Apr 24. doi: 10.1152/ajplung.00104.2026. Online ahead of print.ABSTRACTPulmonary arterial hypertension (PAH) is a fatal vasculopathy driven by pro-inflammatory signaling that leads to pulmonary vascular remodeling and ultimately, right ventricular failure. Ex
Rev Gastroenterol Peru. 2026 Jan-Mar;46(1):88-91.ABSTRACTMesenteric venous thrombosis is an uncommon but highly morbid condition with nonspecific clinical manifestations that may delay early diagnosis. We report the case of a 65-year-old man with a history of venous insufficiency and chronic smoking
Eur Heart J. 2026 Apr 24:ehag186. doi: 10.1093/eurheartj/ehag186. Online ahead of print.ABSTRACTBACKGROUND AND AIMS: The coexistence of moderate mitral regurgitation (MR) and severe tricuspid regurgitation (TR) is common, yet evidence guiding optimal management remains limited. Transcatheter edge-to
J Gen Physiol. 2026 May 4;158(3):e202413734. doi: 10.1085/jgp.202413734. Epub 2026 Apr 24.ABSTRACTCalmodulinopathies are caused by mutations in calmodulin (CaM) and result in debilitating cardiac arrythmias such as long-QT syndrome (LQTS) and catecholaminergic polymorphic ventricular tachycardia (CP
