Evaluating fitness-for-use of electronic health records in ascertaining baseline characteristics and clinical outcomes in clinical trials: insights from the VESALIUS EHR demonstration project

Trials. 2026 Apr 25. doi: 10.1186/s13063-026-09683-7. Online ahead of print.ABSTRACTINTRODUCTION: A tremendous amount of clinical data is collected and stored in electronic health records (EHRs). Whether this data can be harnessed at scale to facilitate clinical trial conduct remains to be seen.METH

P Pishoy Gouda

Unplanned pregnancy and contraceptive use in humanitarian settings: the case of Syrian refugee women in Lebanon

Confl Health. 2026 Apr 25. doi: 10.1186/s13031-026-00792-3. Online ahead of print.ABSTRACTBACKGROUND: Contraception is a vital component of reproductive health, yet refugee women often face multiple barriers to accessing family planning (FP) services. This study aimed to explore contraception experi

S Samar Karout

Early outcomes and resource utilization across contemporary transcatheter and surgical valve interventions: a single-center observational study

No abstractBMC Res Notes. 2026 Apr 24. doi: 10.1186/s13104-026-07824-4. Online ahead of print.NO ABSTRACTPMID:42032750 | DOI:10.1186/s13104-026-07824-4

A Andra Denis Marinescu

Evaluation of nursing performance during coronary artery bypass grafting surgeries using machine learning analysis of surgical videos: a multicenter retrospective study

No abstractJ Cardiothorac Surg. 2026 Apr 24. doi: 10.1186/s13019-026-04233-3. Online ahead of print.NO ABSTRACTPMID:42032742 | DOI:10.1186/s13019-026-04233-3

Q Qing Tang

Comprehensive evaluation of the triglyceride glucose index (TyG) and body roundness index (BRI) on cardiovascular disease risk prediction: a 9-year prospective cohort study in Chinese middle-aged and older adults

Cardiovasc Diabetol. 2026 Apr 24. doi: 10.1186/s12933-026-03092-5. Online ahead of print.ABSTRACTBACKGROUND: Cardiovascular disease (CVD) remains a leading cause of mortality in China. The triglyceride-glucose (TyG) index and body roundness index (BRI)-have separately shown associations with CVD ris

M Mengyao Gu

SGLT-2 inhibitor-associated significant hypernatremia and euglycemic diabetic ketoacidosis after cardiac surgery: a case series

J Cardiothorac Surg. 2026 Apr 24. doi: 10.1186/s13019-026-04141-6. Online ahead of print.ABSTRACTBACKGROUND: Sodium-glucose cotransporter-2 inhibitors (SGLT-2i) were initially developed for the treatment of type 2 diabetes mellitus. Subsequent studies demonstrated their beneficial effects in improvi

E En-Ze Bian

Pulmonary arterial hypertension caused by compression of the left lower pulmonary vein in children

No abstractJ Cardiothorac Surg. 2026 Apr 24. doi: 10.1186/s13019-026-04085-x. Online ahead of print.NO ABSTRACTPMID:42032662 | DOI:10.1186/s13019-026-04085-x

L Li Chen

Therapeutic TG2 inhibition reverses systemic multiomic dysregulation in celiac disease

No abstractBMC Med. 2026 Apr 24. doi: 10.1186/s12916-026-04892-y. Online ahead of print.NO ABSTRACTPMID:42032651 | DOI:10.1186/s12916-026-04892-y

V Valeriia Dotsenko

Trend and clinical outcomes of transcatheter aortic valve replacement in connective tissue disease from the national inpatient sample database (2016-2022)

J Cardiothorac Surg. 2026 Apr 24. doi: 10.1186/s13019-026-04170-1. Online ahead of print.ABSTRACTPURPOSE: Given the systemic nature of connective tissue diseases (CTD), open surgical intervention for aortic stenosis is often considered high risk, making transcatheter aortic valve replacement (TAVR)

F Farah Yasmin

Cost of illness of type 2 diabetes mellitus with a cardiovascular comorbidity and comparison with guideline recommendations: a German claims data analysis

No abstractBMC Health Serv Res. 2026 Apr 24. doi: 10.1186/s12913-026-14428-y. Online ahead of print.NO ABSTRACTPMID:42032593 | DOI:10.1186/s12913-026-14428-y

S Stephan Martin

Multimodal deep learning for cardiovascular disease detection using pulse wave and vocal signals: a prediction model development and validation study

No abstractBMC Med Inform Decis Mak. 2026 Apr 24. doi: 10.1186/s12911-026-03518-w. Online ahead of print.NO ABSTRACTPMID:42032577 | DOI:10.1186/s12911-026-03518-w

Y Yi Lyu

Mastering self-care: a qualitative exploration of the psychological and behavioral experiences of older heart failure patients living alone during hospital discharge preparation

BMC Nurs. 2026 Apr 24. doi: 10.1186/s12912-026-04636-6. Online ahead of print.ABSTRACTBACKGROUND: The transition from hospital to home presents significant psychological and practical challenges for older heart failure patients living alone (OHELP), who must navigate complex self-care needs within a

H Huiyue Zhou

Perioperative pulmonary infection prevention and management in adult patients after coronary artery bypass grafting: a summary of best evidence

No abstractBMC Cardiovasc Disord. 2026 Apr 24. doi: 10.1186/s12872-026-05906-6. Online ahead of print.NO ABSTRACTPMID:42032480 | DOI:10.1186/s12872-026-05906-6

Y Yangyao Peng

Plasma proteomics of extracellular vesicles identifies key proteins correlating to postoperative atrial fibrillation after coronary artery bypass surgery

No abstractClin Proteomics. 2026 Apr 24. doi: 10.1186/s12014-026-09606-3. Online ahead of print.NO ABSTRACTPMID:42032453 | DOI:10.1186/s12014-026-09606-3

H Huan-Xin Chen

Prunetin-Functionalized Small-Diameter Vascular Grafts Attenuate Restenosis through Endothelial Regeneration

ACS Appl Mater Interfaces. 2026 Apr 24. doi: 10.1021/acsami.5c26197. Online ahead of print.ABSTRACTTissue-engineered vascular grafts (TEVGs), particularly small-diameter vascular grafts (SDVGs), continue to face significant clinical challenges such as delayed endothelialization, acute thrombosis, an

Y Yuxi Huang

Secondary Microbial Infection in Pyoderma Gangrenosum: Comparable Rates to Venous Ulcers in a Retrospective Cohort

Wound Repair Regen. 2026 Mar-Apr;34(2):e70161. doi: 10.1111/wrr.70161.ABSTRACTPyoderma gangrenosum (PG) is a neutrophilic dermatosis traditionally regarded as a sterile inflammatory ulcer; however, positive wound cultures are frequently encountered in clinical practice and may complicate or delay di

K Katelyn S Stenger

Contactless 12-lead electrocardiogram via deep computational radar

NPJ Biomed Innov. 2026 Jan 16;3(1):6. doi: 10.1038/s44385-025-00060-8.ABSTRACTCardiovascular disease (CVD) remains the leading cause of global mortality, highlighting the need for scalable, continuous, and contactless diagnostics. Traditional electrocardiogram (ECG) systems, though essential for det

Z Zhi Lu

Generation and applications of cardiac spheroids

NPJ Biomed Innov. 2025 Jun 10;2(1):17. doi: 10.1038/s44385-025-00024-y.ABSTRACTCardiac spheroids (CSs) offer valuable insights into the fundamental aspects of cardiac biology as they model molecular, cellular, and extracellular features typical of the myocardium. This review introduces current engin

D Dana Idais

Physician burnout and type D personality relate to pericoronary fat phenotype and role of sympathetic activation: a cross-sectional study

Sci Rep. 2026 Apr 24. doi: 10.1038/s41598-026-50320-9. Online ahead of print.ABSTRACTBiological pathways linking psychosocial stress to coronary pathology remain elusive. Burnout and type D personality (TDP), defined by negative affectivity and social inhibition, are prevalent among physicians and a

R Roland von Känel

Identification of Mitochondrial Signature Biomarkers and Molecular Mechanisms in Atherosclerotic Tissues and Blood: Combined Single-Cell and Bulk RNA Sequencing Analysis

Mol Neurobiol. 2026 Apr 24;63(1):585. doi: 10.1007/s12035-026-05882-0.ABSTRACTAtherosclerosis (AS) is a leading cause of cardiovascular disease and stroke. Although mitochondria's role in AS is recognized, effective molecular targets are lacking. This study investigated mitochondria-associated signa

L Liang Feng

RAB27A silencing modulates miR-30d-5p expression and extracellular vesicle non-coding RNA cargo in diabetic podocytes

No abstractSci Rep. 2026 Apr 24. doi: 10.1038/s41598-026-49921-1. Online ahead of print.NO ABSTRACTPMID:42032155 | DOI:10.1038/s41598-026-49921-1

O Olga Martinez-Arroyo

Neckband-type earphone for continuous monitoring of cardiovascular symptoms via self-powered box knot pulse-wave sensor

NPJ Biomed Innov. 2025 Feb 12;2(1):4. doi: 10.1038/s44385-025-00007-z.ABSTRACTBlood pressure (BP) assessment is one of the essential vital signs in the clinical field because of its significant relation with various chronic diseases. For effective continuous BP monitoring at home, the system should

T Tae-Ho Kim

Exosomes: bridge metabolic regulation in cardiac repair

NPJ Biomed Innov. 2025 Jul 2;2(1):21. doi: 10.1038/s44385-025-00030-0.ABSTRACTCardiac repair following cardiovascular diseases relies heavily on coordinated metabolism across different cells. Exosomes, or small extracellular vesicles secreted by cells, have emerged as pivotal regulators of the metab

L Lewen Mao

Tissue-selective COPII modulator SEC16B aggravates cardiovascular disease by promoting lipid export

EMBO J. 2026 Apr 24. doi: 10.1038/s44318-026-00754-8. Online ahead of print.ABSTRACTThe biogenesis and transport of lipoproteins are essential for systemic homeostasis and cardiometabolic health, yet how the secretory pathway acquires specialization to support high-capacity lipoprotein export remain

X Xiao Wang