Cologne (Germany): Institute for Quality and Efficiency in Health Care (IQWiG); 2026 Feb 22.ABSTRACTRESEARCH QUESTION: The aim of this report is toassess the benefit of diagnostics using cardiac magnetic resonance imaging as part of a diagnostic strategy, compared with a diagnostic strategy without
BMC Womens Health. 2026 Feb 9. doi: 10.1186/s12905-026-04315-3. Online ahead of print.ABSTRACTBACKGROUND: Whether physical activity (PA) levels relate to mortality in postmenopausal women remains not well understood.METHODS: We analyzed 5,880 postmenopausal women from NHANES 2007-2018 (median follow
BMC Geriatr. 2026 Feb 9. doi: 10.1186/s12877-026-07129-y. Online ahead of print.ABSTRACTBACKGROUND: Early identification of disability risk in community-dwelling older adults has emerged as a critical public health priority. An increasing number of studies have focused on developing predictive model
BMC Cardiovasc Disord. 2026 Feb 10. doi: 10.1186/s12872-026-05608-z. Online ahead of print.ABSTRACTBACKGROUND: Kawasaki disease shock syndrome (KDSS) is a severe and uncommon complication of Kawasaki disease (KD). Grisel's syndrome (GS), a rare non-traumatic atlantoaxial subluxation, has been seldom
Med Biol Eng Comput. 2026 Feb 10. doi: 10.1007/s11517-025-03512-w. Online ahead of print.ABSTRACTCardiac segmentation and quantification of cardiac function indicators play a crucial role in the clinical diagnosis and treatment of cardiovascular diseases. To address the issue of blurred cardiac cham
Intensive Care Med Exp. 2026 Feb 10;14(1):15. doi: 10.1186/s40635-026-00857-w.ABSTRACTBACKGROUND: The renin-angiotensin system (RAS) plays a critical role in vascular homeostasis and inflammation, and its dysregulation has been implicated in the pathophysiology of COVID-19. We investigated the dynam
Commun Med (Lond). 2026 Feb 9. doi: 10.1038/s43856-025-01310-x. Online ahead of print.ABSTRACTBACKGROUND: Vascular properties of the retina are indicative of both ocular and systemic cardio- and cerebrovascular health. However, the specific relationships between retinal and non-retinal vascular phen
NPJ Sci Food. 2026 Feb 9. doi: 10.1038/s41538-026-00749-z. Online ahead of print.ABSTRACTIn this 12-week trial, 136 participants with moderately dyslipidemia were randomly assigned to receive Lactiplantibacillus plantarum (LP) or placebo. In the intention-to-treat analysis, the group-by-time interac
Nat Commun. 2026 Feb 9;17(1):1446. doi: 10.1038/s41467-025-67449-2.ABSTRACTType 2 diabetes and hypertension are common health conditions that often occur together, suggesting shared biological mechanisms. To explore this relationship, we analyse large-scale multiomic data to uncover genetic factors
Signal Transduct Target Ther. 2026 Feb 10;11(1):50. doi: 10.1038/s41392-025-02566-4.ABSTRACTOcular neovascular and neurodegenerative diseases, such as diabetic retinopathy and age-related macular degeneration, are characterized by abnormal angiogenesis, vascular leakage, and progressive retinal neur
Alzheimers Dement. 2026 Feb;22(2):e71110. doi: 10.1002/alz.71110.ABSTRACTINTRODUCTION: Understanding comorbidities' combined impacts on dementia risk may offer a more comprehensive understanding of individuals' risk. Using machine-learning, we grouped individuals with similar midlife risk profiles i
J Epidemiol Community Health. 2026 Feb 9:jech-2025-225138. doi: 10.1136/jech-2025-225138. Online ahead of print.ABSTRACTBACKGROUND: Layoffs may affect the health of those who lose their jobs as well as those who remain employed. Existing studies have found that remaining employed through layoffs is
Zhonghua Xue Ye Xue Za Zhi. 2026 Jan 14;47(1):96-102. doi: 10.3760/cma.j.cn121090-20250209-00060.ABSTRACTWith the development of high-throughput sequencing technology, clonal hematopoiesis has received extensive attention in the research of cardiovascular, cerebrovascular, and hematological diseases
Zhonghua Xue Ye Xue Za Zhi. 2026 Jan 14;47(1):83-86. doi: 10.3760/cma.j.cn121090-20250421-00195.ABSTRACTWe retrospectively analyzed the clinical data and clonal architecture of two multiple myeloma (MM) patients harboring concurrent IGH::FGFR3 and IGH::CCND1 fusions, with a review of relevant litera
Zhonghua Xue Ye Xue Za Zhi. 2026 Jan 14;47(1):14-20. doi: 10.3760/cma.j.cn121090-20250925-00442.ABSTRACTGenetic abnormalities are a cornerstone for prognostic assessment in multiple myeloma (MM) and form the basis of contemporary risk-stratification systems. In routine clinical practice, cytogenetic
BMJ Open. 2026 Feb 9;16(2):e105575. doi: 10.1136/bmjopen-2025-105575.ABSTRACTOBJECTIVES: Patient self-testing (PST) for warfarin management is well-established in developed countries but remains underused in developing regions. This study compared the safety and effectiveness of PST with usual care
BMJ Open. 2026 Feb 9;16(2):e109126. doi: 10.1136/bmjopen-2025-109126.ABSTRACTINTRODUCTION: Peripheral artery disease (PAD) affected approximately 800 000 Canadians aged 25 years or older in 2015 and it poses a substantial risk of lower extremity amputation (LEA). While clinical risk factors for ampu
BMJ Open. 2026 Feb 9;16(2):e095515. doi: 10.1136/bmjopen-2024-095515.ABSTRACTINTRODUCTION: Dementia contributes to the disease burden worldwide, and people with hypertension or type 2 diabetes are at an elevated risk of developing dementia. It is essential to prevent or delay cognitive decline in pe
BMJ Open. 2026 Feb 9;16(2):e111336. doi: 10.1136/bmjopen-2025-111336.ABSTRACTINTRODUCTION: The number of people living with obesity is increasing rapidly worldwide, and the WHO estimates approximately 5 million deaths yearly from non-communicable diseases related to elevated body mass index (BMI). T
Lupus Sci Med. 2026 Feb 9;13(1):e001770. doi: 10.1136/lupus-2025-001770.ABSTRACTOBJECTIVE: Dyslipidaemia in systemic lupus erythematosus (SLE) contributes to pathogenesis and cardiovascular risk. The effect of statin therapy on SLE disease activity remains controversial. This meta-analysis systemati
Open Heart. 2026 Feb 9;13(1):e003804. doi: 10.1136/openhrt-2025-003804.ABSTRACTBACKGROUND: Previous studies have suggested an adverse role of epicardial adipose tissue (EAT) in aortic stenosis (AS), potentially mediated by direct effects on the myocardium. This study aimed to assess whether EAT volu
Thromb Haemost. 2026 Feb 9. doi: 10.1055/a-2761-5903. Online ahead of print.ABSTRACTThrombosis drives substantial global mortality across atrial fibrillation, venous thromboembolism, and atherosclerosis. However, clinical scores treat risk as a static variable and omit evolving comorbidities, functi
Food Chem Toxicol. 2026 Feb 7:116001. doi: 10.1016/j.fct.2026.116001. Online ahead of print.ABSTRACTBACKGROUND: Long-term arsenic exposure is associated with health risks, including neurotoxicity, cardiovascular diseases, and cancer, with heightened vulnerability during early development. This study
Heart Rhythm. 2026 Feb 7:S1547-5271(26)00120-7. doi: 10.1016/j.hrthm.2026.01.053. Online ahead of print.ABSTRACTBACKGROUND: Desmoglein-2 (DSG2)-associated cardiomyopathy represents a distinct subset of arrhythmogenic cardiomyopathy (ACM). A founder variant, NM_001943.5 (DSG2): c.T1592G (p.Phe531Cys)
