Secondary prevention and management of dyslipidaemia in patients with coronary artery disease on statin therapy in a tertiary academic centre in Johannesburg

Cardiovasc J Afr. 2025 Oct 9;36(3):323-330. doi: 10.5830/CVJA-2025-035. Epub 2025 Sep 30.ABSTRACTOptimal low-density lipoprotein cholesterol (LDL-C) control in patients with established atherosclerotic cardiovascular disease (ASCVD) is defined as LDL-C levels less than 1.4 mmol/L and a reduction of

P Patience Ntila

Association Between NHHR and Future Cardiovascular Disease Among Patients With CKM Stages 0-3: A Nationwide Prospective Cohort Study

J Clin Hypertens (Greenwich). 2026 Mar;28(3):e70221. doi: 10.1111/jch.70221.ABSTRACTThe American Heart Association recently proposed the concept of Cardiovascular-kidney-metabolic (CKM) syndrome, emphasizing the interconnections among cardiovascular disease (CVD), chronic kidney disease (CKD), and m

Y Yu Huang

Association of SGLT2 inhibitors and new-onset dementia in non-diabetic patients with heart failure

Eur J Heart Fail. 2026 Feb 10:xuag038. doi: 10.1093/ejhf/xuag038. Online ahead of print.ABSTRACTAIMS: Patients with heart failure (HF) are at increased risk of developing dementia, an outcome that substantially worsens clinical prognosis and quality of life. Sodium-glucose co-transporter 2 inhibitor

A Abdelhakim Hacil

Artificial intelligence to investigate metabolomics data for precision medicine

Metabolomics. 2026 Feb 27;22(2):29. doi: 10.1007/s11306-026-02401-z.ABSTRACTBACKGROUND: Metabolomic data offers insights into disease mechanisms, diagnostics, and therapeutic targets by analyzing metabolic profiles. In analyzing these profiles, traditional bioinformatic and statistical approaches, w

A Antony Shenouda

The impact of sex and gender on Fibromyalgia Syndrome: data from the Italian Fibromyalgia Registry

Intern Emerg Med. 2026 Feb 27. doi: 10.1007/s11739-026-04277-2. Online ahead of print.ABSTRACTMost fibromyalgia (FM) patients are women, with a female-to-male ratio of 3:1. While sex differences in pain perception and description have been reported, the impact of sex and gender on FM severity remain

C Cristina Iannuccelli

Upfront Combination or Stepwise Escalation: Personalising LDL-C Reduction in Clinical Practice

No abstractCurr Atheroscler Rep. 2026 Feb 27;28(1):29. doi: 10.1007/s11883-026-01400-8.NO ABSTRACTPMID:41758439 | DOI:10.1007/s11883-026-01400-8

A Angela Pirillo

Elevated low-density lipoprotein cholesterol levels and prostate cancer risk: UK Biobank evidence

No abstractWorld J Urol. 2026 Feb 27;44(1):210. doi: 10.1007/s00345-026-06313-4.NO ABSTRACTPMID:41758417 | DOI:10.1007/s00345-026-06313-4

R R Alexa

Exploring the potential mechanisms of hydroquinone on bladder cancer using network toxicology, Mendelian randomization analysis, molecular docking, and molecular dynamics simulations

No abstractDiscov Oncol. 2026 Feb 27. doi: 10.1007/s12672-025-04114-6. Online ahead of print.NO ABSTRACTPMID:41758391 | DOI:10.1007/s12672-025-04114-6

Y Yu Li

Cardiac MRI monitoring in acute myocarditis: predicting outcomes through serial imaging

Eur Radiol. 2026 Feb 27. doi: 10.1007/s00330-026-12325-w. Online ahead of print.ABSTRACTOBJECTIVES: Myocarditis is a common disease with a risk of chronic progression. The aim of this study is to assess changes in MRI parameters during serial monitoring in patients with acute myocarditis (AM), and t

A Anna Palmisano

Feasibility of remnant cholesterol as a therapeutic target for atherosclerotic cardio-vascular disease

Expert Opin Ther Targets. 2026 Feb 27. doi: 10.1080/14728222.2026.2639678. Online ahead of print.ABSTRACTINTRODUCTION: Elevated plasma concentration of remnant cholesterol, the cholesterol in triglyceride-rich lipoproteins, is associated with increased risk of atherosclerotic cardiovascular disease(

A Anders Berg Wulff

T-TEER-interventional repair of tricuspid regurgitation

Herz. 2026 Feb 27. doi: 10.1007/s00059-026-05373-x. Online ahead of print.ABSTRACTSevere tricuspid regurgitation (TR) is a common right-sided valvular disease associated with a substantially increased risk of morbidity, hospitalization, and mortality. Transcatheter tricuspid edge-to-edge repair (T-T

D Dominik Berliner

Prototype Learning to Create Refined Interpretable Digital Phenotypes from ECGs

Pac Symp Biocomput. 2026;31:679-693. doi: 10.1142/9789819824755_0049.ABSTRACTPrototype-based neural networks offer interpretable predictions by comparing inputs to learned, representative signal patterns anchored in training data. While such models have shown promise in the classification of physiol

S Sahil Sethi

Systematic Review of International Population Studies With Cardiac Magnetic Resonance and Genomics Research Data ("Imagenomics")

JACC Cardiovasc Imaging. 2026 Feb 20:S1936-878X(26)00050-1. doi: 10.1016/j.jcmg.2026.01.007. Online ahead of print.ABSTRACTEpidemiological population studies may include cardiac magnetic resonance (CMR)-derived phenotyping and large-scale genotyping, providing unprecedented level of detail to invest

K Kerrick Hesse

Intracoronary Imaging and Transcriptomic Characteristics Before and After Maximum Lipid-Lowering Therapy: YELLOW-III Study of Evolocumab and Maximum Statin Therapy in Chronic Coronary Disease

JACC Cardiovasc Imaging. 2026 Feb 24:S1936-878X(26)00052-5. doi: 10.1016/j.jcmg.2025.12.013. Online ahead of print.ABSTRACTBACKGROUND: Despite extensive evidence of the beneficial effects of proprotein convertase subtilisin/kexin type 9 inhibition on clinical outcomes, the mechanisms for favorable o

A Annapoorna S Kini

Deep Learning and Fluid Dynamics On-Site CT-FFR Solution Compared to Off-Site FFRct and Invasive FFR

JACC Cardiovasc Imaging. 2026 Feb 20:S1936-878X(25)00708-9. doi: 10.1016/j.jcmg.2025.11.011. Online ahead of print.ABSTRACTBACKGROUND: On-site computed tomography (CT)-derived fractional flow reserve (FFR) solutions are increasingly needed to reduce delays, costs, and reliance on external platforms.

F Fabio Fazzari

New 10-Year Atherosclerosis Cardiovascular Disease Risk Score for Asian and American Indian Women Service Members

JACC Asia. 2026 Feb 16:S2772-3747(26)00037-2. doi: 10.1016/j.jacasi.2026.01.003. Online ahead of print.ABSTRACTBACKGROUND: To date, there is no validated atherosclerosis cardiovascular disease risk calculator developed for Asian/Hawaiian (Asian) Americans and American Indian/Alaska Native (AI) women

H Haekyung Jeon-Slaughter

Cardiovascular Disease in Asia: Decreasing Rates and Increasing Absolute Burden

No abstractJACC Asia. 2026 Feb 12:S2772-3747(26)00052-9. doi: 10.1016/j.jacasi.2025.12.023. Online ahead of print.NO ABSTRACTPMID:41758102 | DOI:10.1016/j.jacasi.2025.12.023

H Hyeon Chang Kim

Spotlight on Overlooked Risk in Women Veterans: Addressing Equity Gaps

No abstractJACC Asia. 2026 Feb 20:S2772-3747(26)00081-5. doi: 10.1016/j.jacasi.2026.01.021. Online ahead of print.NO ABSTRACTPMID:41758101 | DOI:10.1016/j.jacasi.2026.01.021

J Jen Ping Lee

Normalized QRS Duration by LV Dimension: Eliminating Sex-Specific Differences and Predicting Cardiac Resynchronization Therapy Outcomes

JACC Clin Electrophysiol. 2026 Feb 26:S2405-500X(26)00106-4. doi: 10.1016/j.jacep.2026.01.032. Online ahead of print.ABSTRACTBACKGROUND: Increasing evidence shows sex-specific differences in the efficacy of cardiac resynchronization therapy (CRT). Without a clear cardiac rationale, relying solely on

E Enrui Zhang

Left Atrial Appendage Occlusion in Atrial Fibrillation With Structural Heart Disease: Progress, Promise, and Gaps

No abstractJACC Clin Electrophysiol. 2026 Feb 26:S2405-500X(26)00014-9. doi: 10.1016/j.jacep.2026.01.009. Online ahead of print.NO ABSTRACTPMID:41758090 | DOI:10.1016/j.jacep.2026.01.009

A Arwa Younis

Carotid plaque macrophage burden and inflammatory lipid-associated macrophage markers predict secondary major adverse cardiovascular events after endarterectomy

Eur Heart J. 2026 Feb 27:ehag117. doi: 10.1093/eurheartj/ehag117. Online ahead of print.ABSTRACTBACKGROUND AND AIMS: Atherosclerosis is a chronic lipid-driven inflammatory disease and one of the leading underlying causes of cardiovascular morbidity and mortality in Western society. Macrophages are k

K Koen H M Prange

Local apocynin improves acetylcholine- but not insulin-mediated vasodilation in the cutaneous microvasculature of women with a history of gestational diabetes

J Appl Physiol (1985). 2026 Feb 27. doi: 10.1152/japplphysiol.01080.2025. Online ahead of print.ABSTRACTWomen with a history of gestational diabetes mellitus (GDM) are at a significantly greater risk of developing cardiovascular disease and type 2 diabetes compared to healthy control (HC) women who

G Grace S Maurer

Hepatocellular carcinoma in Fontan-associated liver disease: Incidence, risk stratification, and surveillance implications

Hepatol Commun. 2026 Feb 26;10(3):e00910. doi: 10.1097/HC9.0000000000000910. eCollection 2026 Mar 1.ABSTRACTBACKGROUND: Hepatocellular carcinoma (HCC) is a serious complication of Fontan-associated liver disease (FALD). However, data on its incidence, risk factors, and outcomes in this rare populati

H Hideki Onishi

Diagnostic Value of miR-1225-5p in Acute Coronary Syndrome and its Mechanism in ox-LDL Induced Human Coronary Artery Endothelial Cells Injury

Clin Appl Thromb Hemost. 2026 Jan-Dec;32:10760296251414428. doi: 10.1177/10760296251414428. Epub 2026 Feb 27.ABSTRACTBackgroundAcute coronary syndrome (ACS), a life-threatening cardiovascular emergency, faces challenges in early diagnosis and risk stratification. MicroRNAs (miRNAs) have emerged as k

H Han Ju