Cologne (Germany): Institute for Quality and Efficiency in Health Care (IQWiG); 2026 Feb 22.ABSTRACTRESEARCH QUESTION: The aim of this report is toassess the benefit of diagnostics using cardiac magnetic resonance imaging as part of a diagnostic strategy, compared with a diagnostic strategy without
Ther Adv Cardiovasc Dis. 2026 Jan-Dec;20:17539447251406847. doi: 10.1177/17539447251406847. Epub 2026 Feb 19.ABSTRACTArtificial intelligence (AI) and machine learning are rapidly transforming cardiac electrophysiology, offering new avenues for diagnosing, managing, and treating cardiac arrhythmias.
J Endovasc Ther. 2026 Feb 19:15266028261424732. doi: 10.1177/15266028261424732. Online ahead of print.ABSTRACTPURPOSE: Peripheral arterial disease (PAD) is a major global health burden often requiring endovascular intervention. Complex lesion morphologies such as calcification or long occlusions lim
Circ Res. 2026 Feb 19. doi: 10.1161/CIRCRESAHA.125.326990. Online ahead of print.ABSTRACTBACKGROUND: The nervous, gastrointestinal, renal, and cardiovascular systems orchestrate ion-fluid homeostasis and impose reciprocal adaptations to hypertensive challenges. Mechanistic insight into the interorga
Arterioscler Thromb Vasc Biol. 2026 Feb 19. doi: 10.1161/ATVBAHA.125.321675. Online ahead of print.ABSTRACTPreeclampsia, a condition characterized by new-onset hypertension during pregnancy and ≥1 indices of organ damage, is a major driver of both short- and long-term maternal health outcomes. Indiv
Arterioscler Thromb Vasc Biol. 2026 Feb 19. doi: 10.1161/ATVBAHA.125.323552. Online ahead of print.ABSTRACTBACKGROUND: TF (transcription factor) Prdm16 (positive regulatory domain-containing protein 16) regulates hematopoietic and neuronal stem cell homeostasis, adipose differentiation, and cardiac
Arterioscler Thromb Vasc Biol. 2026 Feb 19. doi: 10.1161/ATVBAHA.125.322135. Online ahead of print.ABSTRACTPeripheral artery disease (PAD) affects millions worldwide and is associated with high mortality, major amputations, and detrimental effects on functional and health status. PAD management is m
Circ Cardiovasc Interv. 2026 Feb 19:e015984. doi: 10.1161/CIRCINTERVENTIONS.125.015984. Online ahead of print.ABSTRACTParavalvular leak (PVL) is a well-known complication of valve replacement, occurring in up to 10% of aortic and 17% of mitral prosthetic valves. Although many leaks are small and cli
Circ Cardiovasc Imaging. 2026 Feb 19:e019264. doi: 10.1161/CIRCIMAGING.125.019264. Online ahead of print.ABSTRACTRight ventricular (RV) failure is a principal determinant of morbidity and mortality in children with pulmonary hypertension, making accurate RV assessment a cornerstone of risk stratific
Theor Biol Forum. 2025 Jul 1;118(1-2):67-110. doi: 10.19272/202511402006.ABSTRACTAtherosclerosis and diabetes are largely recognized as inflammatory disorders underlying cardiovascular disease. C-reactive protein, interleukin-6 and fibrinogen constitute the most established inflammatory biomarkers i
Pharm Stat. 2026 Mar-Apr;25(2):e70079. doi: 10.1002/pst.70079.ABSTRACTThe advancement of precision medicine hinges on accurately tailored diagnostic strategies yet estimating reliable confidence intervals (CIs) for the maximal partial Youden Index under verification bias presents considerable challe
J Antimicrob Chemother. 2026 Feb 2;81(3):dkag053. doi: 10.1093/jac/dkag053.ABSTRACTBACKGROUND: Limited data exist on whether the presence of type-2 diabetes mellitus (T2DM) increases the risk of significant liver fibrosis (LF) among people with HIV (PWH) and metabolic dysfunction-associated steatoti
Front Immunol. 2026 Feb 3;17:1752471. doi: 10.3389/fimmu.2026.1752471. eCollection 2026.ABSTRACTStroke remains a leading cause of death and disability worldwide, and inflammation is increasingly recognized as a key driver of acute injury and secondary neurodegeneration. Among post-stroke immune medi
Front Pediatr. 2026 Feb 3;13:1748925. doi: 10.3389/fped.2025.1748925. eCollection 2025.ABSTRACTBACKGROUND: In 2024, new international consensus criteria for pediatric sepsis and septic shock (2024 criteria) were introduced, replacing the 2005 criteria. The 2024 criteria use the Phoenix Sepsis Score
Open Forum Infect Dis. 2026 Feb 5;13(2):ofag052. doi: 10.1093/ofid/ofag052. eCollection 2026 Feb.ABSTRACTBACKGROUND: Dysregulated inflammatory processes have been associated with severe COVID-19 disease. Ceramides, bioactive lipids involved in inflammatory signaling, have been utilized to predict ou
ACS Pharmacol Transl Sci. 2026 Jan 10;9(2):359-369. doi: 10.1021/acsptsci.5c00615. eCollection 2026 Feb 13.ABSTRACTPeroxynitrite causes oxidative DNA damage that can lead to cancer, cardiovascular, and neurodegenerative diseases. Polyphenol compounds have been extensively studied for their ability t
Diabetes Metab Syndr Obes. 2026 Feb 10;19:559587. doi: 10.2147/DMSO.S559587. eCollection 2026.ABSTRACTGlucose-dependent insulinotropic polypeptide (GIP), once the overlooked sibling of the incretin family, is now experiencing a research renaissance. Historically, its therapeutic development was hind
Diabetes Metab Syndr Obes. 2026 Feb 12;19:555812. doi: 10.2147/DMSO.S555812. eCollection 2026.ABSTRACTPURPOSE: Although eating habits of "vegetables first" have been reported to be effective in suppressing postprandial hyperglycemia, its association with complications in diabetic patients remains un
Diabetes Metab Syndr Obes. 2026 Feb 12;19:547492. doi: 10.2147/DMSO.S547492. eCollection 2026.ABSTRACTPURPOSE: Type 2 diabetes (T2D) is often associated with hypertension and dyslipidemia and is known to increase the risk for cardiovascular disease (CVD). A fixed-dose diabetes polypill, which can lo
Diabetes Metab Syndr Obes. 2026 Feb 10;19:585436. doi: 10.2147/DMSO.S585436. eCollection 2026.ABSTRACTOBJECTIVE: To conduct a systematic, multi-dimensional clinical evaluation of five long-acting glucagon-like peptide-1 receptor agonists (GLP-1RAs) available in China, providing evidence-based guidan
Saudi J Anaesth. 2026 Jan 2;20(1):48-55. doi: 10.4103/sja.sja_528_25. eCollection 2026 Jan-Mar.ABSTRACTBACKGROUND: Managing dental pain in medically compromised patients poses clinical challenges due to altered drug metabolism, systemic contraindications, and increased risk of adverse effects. Exist
Saudi J Anaesth. 2026 Jan 2;20(1):150-155. doi: 10.4103/sja.sja_571_25. eCollection 2026 Jan-Mar.ABSTRACTLocal anesthetics are essential in dental practice, but their systemic effects can pose significant risks for medically compromised patients. This review aims to identify and evaluate the safest
Front Nutr. 2026 Feb 3;12:1739577. doi: 10.3389/fnut.2025.1739577. eCollection 2025.ABSTRACTBACKGROUND: As the impact of early adoption of a sustainable plant-based diet on cardiometabolic biomarkers remains unexplored, we assessed whether they are associated with the Planetary Health Diet Index (PH
Front Nutr. 2026 Feb 3;12:1736964. doi: 10.3389/fnut.2025.1736964. eCollection 2025.ABSTRACTINTRODUCTION: Curcumin, a dietary polyphenol primarily derived from turmeric, has potent antioxidant and anti-inflammatory capabilities against diet-related chronic diseases. A high glycemic diet (HGD) has be
