Computational exploration of Withania coagulans-derived natural inhibitors targeting HMG-CoA reductase: A pharmacokinetic, docking and molecular dynamics study for cholesterol regulation in Mus musculus

Pak J Pharm Sci. 2026 Apr;39(4):999-1020. doi: 10.36721/PJPS.2026.39.4.REG.14438.1.ABSTRACTBACKGROUND: Hypercholesterolemia is a major modifiable risk factor for cardiovascular disease, largely driven by excessive activity of 3-hydroxy-3-methylglutaryl-CoA reductase (Hmgcr), the rate-limiting enzyme

M Muhammad Bilal Azmi

The Predictive Value of P-Wave Dispersion and QTc Dispersion in Preeclampsia

Ann Noninvasive Electrocardiol. 2026 Mar;31(2):e70170. doi: 10.1111/anec.70170.ABSTRACTOBJECTIVE: There is growing evidence that pregnant women with gestational hypertension are more likely to develop cardiovascular disease in the future, including arrhythmias. The objective of this study was to ana

L Liting Zhi