Chirality. 2026 Aug;38(8):e70125. doi: 10.1002/chir.70125.ABSTRACTPomalidomide is a 2nd-generation chiral immunomodulatory (IMiDs) drugs and have antiangiogenic activity. Despite being teratogenic, it has been shown to be effective in treating multiple myeloma. Enantioselectivity, chemical structure
Acad Emerg Med. 2026 Jul;33(7):e70379. doi: 10.1111/acem.70379.ABSTRACTOBJECTIVES: A 0/2-h algorithm for the i-STAT point-of-care (POC) high sensitivity troponin I (hs-cTnI) assay was recently derived in Australia. The objective of this study was to validate and optimize the performance of the 0/2-h
Int J Epidemiol. 2026 Jun 24;55(4):dyag104. doi: 10.1093/ije/dyag104.ABSTRACTBACKGROUND: Cardiovascular disease (CVD) remains a major global health burden, with risk factors evolving alongside socioeconomic and lifestyle changes. The PREVENT equation provides race-free estimates of 10- and 30-year C
Mol Ther. 2026 Jul 17:S1525-0016(26)00604-0. doi: 10.1016/j.ymthe.2026.07.036. Online ahead of print.ABSTRACTFamilial hypercholesterolemia (FH), most frequently caused by LDLR loss-of-function variants, is a common autosomal dominant disorder that leads to early-onset, life-threatening cardiovascula
Am J Case Rep. 2026 Jul 18;27:e953001. doi: 10.12659/AJCR.953001.ABSTRACTBACKGROUND Durvalumab is a humanized monoclonal antibody and immune checkpoint inhibitor used for the treatment of advanced non-small cell lung cancer. Myocarditis, particularly in late-onset cases, is a rare but serious advers
Angiology. 2026 Jul 17:33197261467578. doi: 10.1177/00033197261467578. Online ahead of print.ABSTRACTThyroid hormones may accelerate heart rate and enhance cardiac contractility, improving both systolic and diastolic functions of heart, while reducing systemic vascular resistance at rest. Thyroid dy
Medicine (Baltimore). 2026 Jul 17;105(29):e49678. doi: 10.1097/MD.0000000000049678.ABSTRACTBACKGROUND: Coronary artery lesions (CAL) complicating Kawasaki disease (KD) are a central concern affecting the long-term cardiovascular health of affected children. This study aimed to systematically depict
Medicine (Baltimore). 2026 Jul 17;105(29):e49850. doi: 10.1097/MD.0000000000049850.ABSTRACTSupraventricular tachycardia (SVT) is a common arrhythmic disorder characterized by abnormal electrical impulses arising from supraventricular tissues, most commonly the atria or atrioventricular node. This st
Medicine (Baltimore). 2026 Jul 17;105(29):e49654. doi: 10.1097/MD.0000000000049654.ABSTRACTThis study aimed to investigate the incidence and independent risk factors of early elevated intraocular pressure (IOP) after vitrectomy in patients with diabetes and establish a clinical risk prediction model
Medicine (Baltimore). 2026 Jul 17;105(29):e49691. doi: 10.1097/MD.0000000000049691.ABSTRACTThe association between immunocyte phenotypes and dilated cardiomyopathy (DCM) has been explored, however the exact pathogenesis of the relationship between immune cells and DCM is unclear. This bidirectional
Medicine (Baltimore). 2026 Jul 17;105(29):e49844. doi: 10.1097/MD.0000000000049844.ABSTRACTBACKGROUND: Diabetic cardiomyopathy (DCM) is a significant diabetes complication, primarily due to persistently high blood sugar and metabolic issues. Chronic low-grade inflammation plays a key role in its dev
Medicine (Baltimore). 2026 Jul 17;105(29):e49810. doi: 10.1097/MD.0000000000049810.ABSTRACTBACKGROUND: Occupational therapy (OT) is an important component of stroke rehabilitation, but the global research landscape, collaboration patterns, research hotspots, and emerging trends in OT for stroke have
Medicine (Baltimore). 2026 Jul 17;105(29):e49680. doi: 10.1097/MD.0000000000049680.ABSTRACTThis retrospective observational study aimed to identify clinical determinants of malnutrition in elderly patients with chronic heart failure. Elderly patients (≥65 years) with established chronic heart failur
Medicine (Baltimore). 2026 Jul 17;105(29):e49798. doi: 10.1097/MD.0000000000049798.ABSTRACTCoronary artery disease (CAD) is a leading cause of mortality and morbidity globally, with its elevated rates of disability and death posing a significant public health concern. Vitamin D is a crucial bioactiv
Medicine (Baltimore). 2026 Jul 17;105(29):e49599. doi: 10.1097/MD.0000000000049599.ABSTRACTAlthough gastroesophageal reflux disease (GERD) and pancreatitis are both common gastrointestinal disorders, few studies have investigated their potential causal relationship. Clarifying whether GERD contribut
Medicine (Baltimore). 2026 Jul 17;105(29):e49682. doi: 10.1097/MD.0000000000049682.ABSTRACTArteriovenous fistula (AVF) intimal hyperplasia (IH) is a major pathological basis of AVF stenosis and dysfunction in patients undergoing maintenance hemodialysis. This single-center retrospective observationa
Medicine (Baltimore). 2026 Jul 17;105(29):e49453. doi: 10.1097/MD.0000000000049453.ABSTRACTThe neutrophil percentage-to-albumin ratio (NPAR), calculated from neutrophil percentage and serum albumin levels, has been proposed as an inflammation-related indicator. Despite increasing interest in NPAR as
Medicine (Baltimore). 2026 Jul 17;105(29):e49786. doi: 10.1097/MD.0000000000049786.ABSTRACTChronic kidney disease (CKD) is a global public health challenge associated with elevated all-cause and cardiovascular mortality, driven by chronic inflammation and malnutrition. The neutrophil percentage-to-a
Medicine (Baltimore). 2026 Jul 17;105(29):e49809. doi: 10.1097/MD.0000000000049809.ABSTRACTAcute ischemic stroke remains a major cause of death and disability, and intravenous thrombolysis is central to early reperfusion; however, post-lysis thrombin activity may contribute to rethrombosis and incom
Medicine (Baltimore). 2026 Jul 17;105(29):e49729. doi: 10.1097/MD.0000000000049729.ABSTRACTVenous thromboembolism (VTE) is a leading preventable cause of in-hospital mortality in older adults, yet early risk stratification remains a key clinical challenge. This study aimed to develop and internally
Medicine (Baltimore). 2026 Jul 17;105(29):e49736. doi: 10.1097/MD.0000000000049736.ABSTRACTA large number of functional disorders and uncomfortable symptoms often remain following ischemic stroke (IS). Existing drug therapy is not ideal for the direct improvement of symptoms, which often leads to po
Medicine (Baltimore). 2026 Jul 17;105(29):e49713. doi: 10.1097/MD.0000000000049713.ABSTRACTInflammation plays a key role in complications and organ damage in type 2 diabetes mellitus (T2DM). The Aggregate Index of Systemic Inflammation (AISI) and Systemic Inflammation Response Index (SIRI) have emer
Medicine (Baltimore). 2026 Jul 17;105(29):e49796. doi: 10.1097/MD.0000000000049796.ABSTRACTBlood eosinophil count has been associated with prognosis in patients with cardiovascular disease. However, its prognostic value among critically ill patients with atrial fibrillation (AF) remains unclear. Thi
Medicine (Baltimore). 2026 Jul 17;105(29):e49760. doi: 10.1097/MD.0000000000049760.ABSTRACTIn recent years, with a growing understanding of coronary microvascular dysfunction, myocardial infarction with nonobstructive coronary arteries (MINOCA) has been proposed as a distinct type of myocardial infa
