Beyond the Heart: Marfan Syndrome From the Cardiologist's Perspective

Cardiol Rev. 2025 Nov 20. doi: 10.1097/CRD.0000000000001131. Online ahead of print.ABSTRACTMarfan syndrome is a multisystem connective tissue condition that results in extracellular matrix breakdown and dysregulated transforming growth factor-beta signaling caused by FBN1 mutations. The principal fo

K Kayanne Toutounji

Engasertib versus Placebo for Bleeding in Hereditary Hemorrhagic Telangiectasia

N Engl J Med. 2025 Nov 27;393(21):2131-2141. doi: 10.1056/NEJMoa2504411.ABSTRACTBACKGROUND: Hereditary hemorrhagic telangiectasia (HHT) can cause recurrent, severe epistaxis, as well as anemia and reduced quality of life. The disease remains without licensed therapies worldwide.METHODS: In this proo

H Hanny Al-Samkari

Stress imaging in paediatric and congenital heart disease patients

Eur Heart J Cardiovasc Imaging. 2025 Nov 26:jeaf332. doi: 10.1093/ehjci/jeaf332. Online ahead of print.ABSTRACTStress imaging in paediatric cardiology and congenital heart disease patients has an increasing role for functional assessment. Indications include coronary artery anomalies and disease in

S Suzan Hatipoglu

Iron deficiency impact on exercise performance in patients with heart failure

J Cardiovasc Med (Hagerstown). 2025 Nov 1;26(11):666-673. doi: 10.2459/JCM.0000000000001799. Epub 2025 Sep 26.ABSTRACTIron deficiency is a highly prevalent and clinically significant comorbidity in patients with heart failure, occurring in up to 80% of acute heart failure and over 50% of chronic hea

J Jeness Campodonico