Distinct BAL cytokine signatures define immunopathological endotypes in interstitial lung disease

Front Physiol. 2026 Oct 13;17:1951891. doi: 10.3389/fphys.2026.1951891. eCollection 2026.ABSTRACTBACKGROUND: Interstitial lung disease (ILD) comprises a heterogeneous group of disorders characterized by variable clinical phenotypes and dysregulated immune responses. The marked diversity in disease b

R Rubén Osuna-Gómez

Exploratory predictive value of novel inflammatory biomarkers for microvascular obstruction after emergency revascularization in STEMI patients

Front Med (Lausanne). 2026 Oct 13;13:1946751. doi: 10.3389/fmed.2026.1946751. eCollection 2026.ABSTRACTPURPOSE: To assess the associations of blood cell-derived inflammatory markers with the formation of microvascular obstruction (MVO) and their exploratory predictive performance in STEMI patients a

Y Yang Dai

Functional changes during inpatient pulmonary rehabilitation in Poland: an ICF-based analysis of functioning relevant to healthy aging and public health

Front Public Health. 2026 Oct 13;14:1949234. doi: 10.3389/fpubh.2026.1949234. eCollection 2026.ABSTRACTINTRODUCTION: The International Classification of Functioning, Disability and Health (ICF) provides a comprehensive framework for assessing rehabilitation outcomes beyond traditional physiological

K Karol Pawlak

Potential role of irisin-mediated oxidative stress defense in systemic diseases

Front Cell Dev Biol. 2026 Oct 13;14:1996659. doi: 10.3389/fcell.2026.1996659. eCollection 2026.ABSTRACTOxidative stress arises when excessive reactive oxygen species (ROS) overwhelm endogenous antioxidant defenses, leading to deleterious modifications of lipids, proteins, and DNA. Persistent oxidati

X Xue Xiao

Age-related cardiac dysfunction is not associated with shorter telomere length in laboratory rats

Front Cardiovasc Med. 2026 Oct 13;13:1790767. doi: 10.3389/fcvm.2026.1790767. eCollection 2026.ABSTRACTINTRODUCTION: Ageing is an independent risk factor for cardiovascular disease (CVD). Preclinical models of ageing are needed to better understand human diseases. Telomere shortening is a critical p

S Sindre T Strandberg

Association of NT-proBNP with non-alcoholic fatty liver disease in elderly men with normal BMI and incident heart failure

Front Cardiovasc Med. 2026 Oct 13;13:1846048. doi: 10.3389/fcvm.2026.1846048. eCollection 2026.ABSTRACTBACKGROUND: With the increasing burden of lean nonalcoholic fatty liver disease (NAFLD) and heart failure (HF), understanding the relationship between lean NAFLD and NT-proBNP in elderly patients b

J Jinling Ma

Decoding protein signaling networks in microvascular angina: the multi-target biochemical actions of traditional Chinese medicine

Front Mol Biosci. 2026 Oct 13;13:1908353. doi: 10.3389/fmolb.2026.1908353. eCollection 2026.ABSTRACTAlthough angina pectoris is among the most common conditions in cardiology, a substantial proportion of symptomatic patients exhibit persistent ischemia without flow-limiting epicardial coronary arter

Y Yingkai Duan

Repetitive transcranial magnetic stimulation paired with a 3D-printed ankle-foot orthosis for ankle-foot dysfunction among older adults following subacute stroke: clinical findings and exploratory neurophysiological analyses

Front Neurol. 2026 Oct 13;17:1859162. doi: 10.3389/fneur.2026.1859162. eCollection 2026.ABSTRACTOBJECTIVE: This work evaluated clinical effects of repetitive transcranial magnetic stimulation (rTMS) plus custom-made 3D-printed ankle-foot orthosis (AFO) for older adults living with post-stroke ankle-

Y Yuting Zhang

GlycoRNA-related cellular program scoring identifies Siglec- and myeloid-associated tumor microenvironments for glycoRNA validation

Front Immunol. 2026 Oct 13;17:1928501. doi: 10.3389/fimmu.2026.1928501. eCollection 2026.ABSTRACTBACKGROUND: Glycosylated RNAs (glycoRNAs) represent a recently recognized connection between RNA biology and cell-surface glycobiology. However, whether glycoRNA-related processes are relevant to human t

M Mowei Kong

Understanding the impact of unmet needs on the health and wellbeing of people with stroke, living in the community: a scoping review of reviews

Front Neurol. 2026 Oct 13;17:1861343. doi: 10.3389/fneur.2026.1861343. eCollection 2026.ABSTRACTBACKGROUND: Recovery from stroke may often be incomplete, with unresolved issues persisting as unmet needs. However, the impact of these needs on both the health and wellbeing of people with stroke, subgr

S Susan Hillier

From pathophysiology to therapy: dual and triple agonists as a new frontier in metabolic dysfunction-associated steatotic liver disease

Front Pharmacol. 2026 Oct 13;17:1784959. doi: 10.3389/fphar.2026.1784959. eCollection 2026.ABSTRACTMetabolic dysfunction-associated steatotic liver disease (MASLD) has emerged as the most prevalent chronic liver condition worldwide, reflecting the growing global burden of obesity and type 2 diabetes

C Christiano Argano

Closed-Loop Bioelectronics: From Functional Materials to Autonomous Therapy

Adv Mater. 2026 Oct 28:e75519. doi: 10.1002/adma.75519. Online ahead of print.ABSTRACTClosed-loop bioelectronic systems sense physiological signals, compute adaptive therapeutic decisions, then deliver precisely timed interventions without human oversight, meeting a clinical need that fixed-schedule

N Narlawar Sagar Shrikrishna

Normal-BMI MASLD is Associated with Increased Mortality, Cardiovascular Events, Cancer and Lower GLP-1 Use

J Clin Endocrinol Metab. 2026 Oct 28:dgag439. doi: 10.1210/clinem/dgag439. Online ahead of print.ABSTRACTBACKGROUND: Metabolic dysfunction-associated steatotic liver disease (MASLD) can occur in individuals who are not overweight or have obesity (normal-BMI MASLD), yet disease burden and management

I Isabel Casimiro

Infection-related adverse events associated with T-cell-engaging bispecific agents: A real-world pharmacovigilance study using FAERS/AEMS

Int J Immunopathol Pharmacol. 2026 Jan-Dec;40:3946320261499210. doi: 10.1177/03946320261499210. Epub 2026 Oct 27.ABSTRACTBackgroundT-cell-engaging bispecific agents and related T-cell-engaging therapies are increasingly used across hematologic malignancies and selected solid tumors. Infection is a c

S Shui Liu

Effects of Walnut Consumption on Inflammatory Cytokines and Adipokines in Adults: A Systematic Review and Dose-Response Meta-Analysis

J Hum Nutr Diet. 2026 Dec;39(6):e70354. doi: 10.1111/jhn.70354.ABSTRACTBACKGROUND: Inflammation and dysregulation of adipokines play key roles in the development of metabolic and cardiovascular disorders. Walnuts (Juglans regia L.), rich in polyunsaturated fatty acids, fiber, and antioxidants, may m

G Ghazal Mashayekhi

Association of haematologic parameters with persistent rheumatic heart disease stage in children: a pilot study

Cardiol Young. 2026 Oct 28:1-7. doi: 10.1017/S1047951126124615. Online ahead of print.ABSTRACTPURPOSE: Rheumatic heart disease remains a major cause of cardiovascular morbidity in children. Although echocardiography is central to diagnosis and staging, it does not directly reflect inflammatory proce

N Nida Gülderen Kalay Şentürk

Epicardial Adipose Tissue as a Dynamic Modulator of Coronary Artery Disease Phenotypes: Pathophysiology and Therapeutic Implications

Clin Cardiol. 2026 Oct;49(10):e70509. doi: 10.1002/clc.70509.ABSTRACTBACKGROUND: Epicardial adipose tissue (EAT) represents a localized visceral adipose depot uniquely situated between the myocardium and the visceral layer of the pericardium. Given its proximity to the coronary vasculature and disti

S Seyed Amirhossein Dormiani Tabatabaei

PIH1D2 Loss-of-Function Directs Ciliary and Cell Cycle Defects Resulting in Left Isomerism With or Without Biliary Atresia

Liver Int. 2026 Nov;46(11):e70951. doi: 10.1111/liv.70951.ABSTRACTBACKGROUND & AIMS: Laterality disorders are rare congenital conditions caused by disruption of left-right embryonic patterning, often associated with ciliary dysfunction. Despite the identification of numerous causative genes, the mol

A Alina Kurolap

NEK1 autophosphorylation is disrupted by amyotrophic lateral sclerosis-associated missense variants: activity biomarkers and structural insights

Open Biol. 2026 Oct 7;16(10):260209. doi: 10.1098/rsob.260209.ABSTRACTRare variants in NEK1, encoding a serine/threonine kinase, are among the most consistently implicated genetic contributors to amyotrophic lateral sclerosis (ALS), reported in approximately 2-3% of cases. Yet, while recent studies

S Shalini Agarwal

Gravity-driven flow for intracranial saccular aneurysm filling

J R Soc Interface. 2026 Oct 7;23(243):20250968. doi: 10.1098/rsif.2025.0968.ABSTRACTIntracranial aneurysms (IAs) are life-threatening cerebrovascular malformations in which complete and durable sac closure is the primary goal of endovascular treatments, including coiling, stent-assisted coiling and

T Tirosh Mekler

Predicting cardiovascular disease in peritoneal dialysis patients using glycated proteomics and machine learning: A prospective multicentre study

Clin Transl Med. 2026 Nov;16(11):e70889. doi: 10.1002/ctm2.70889.ABSTRACTBACKGROUND: Cardiovascular disease (CVD) is the leading cause of death among peritoneal dialysis (PD) patients, yet PD-specific biomarkers and prediction models remain limited. This study aimed to identify glycated peptide biom

J Ji Ji

Phenotype rescue through the restoration of full-length dystrophin using CRISPR/Cas9 genome editing in Duchenne muscular dystrophy patient-derived iPSCs carrying the deletion of two exons

Genome Med. 2026 Jul 31;18(1):167. doi: 10.1186/s13073-026-01738-3.ABSTRACTBACKGROUND: Duchenne muscular dystrophy (DMD) is a X-linked disease affecting skeletal and cardiac muscle and is caused by mutations in the dystrophin gene (DMD). Patient-derived induced pluripotent stem cells (iPSCs) serve a

D Davide Rovina

The impact of prior asymptomatic COVID-19 infection on outcomes following coronary bypass surgery

J Cardiothorac Surg. 2026 Jul 29;21(1):853. doi: 10.1186/s13019-026-04489-9.ABSTRACTBACKGROUND: The optimal timing and expected postoperative course of coronary artery bypass grafting (CABG) after asymptomatic coronavirus disease 2019 (COVID-19) remain uncertain. Evidence guiding cardiac surgical pr

E Emre Külahcıoğlu

Pathways linking to behavioural and biological risk factors on diabetes and overweight/obese among adults in urban slums from Western India: a structural equation modelling analysis

J Health Popul Nutr. 2026 Jul 28;45(1):237. doi: 10.1186/s41043-026-01411-w.ABSTRACTBACKGROUND: The prevalence of non-communicable diseases (NCDs) is on the rise in India, exhibiting significant regional disparities. This study aimed to evaluate sociodemographic, behavioural, biological and anthropo

S Sudhanshu Mahajan