Association Between Low Serum microRNA-26a Levels and Major Adverse Cardiovascular or Cerebrovascular Events in Patients Undergoing Hemodialysis

Hemodial Int. 2026 Jun 10. doi: 10.1111/hdi.70086. Online ahead of print.ABSTRACTOBJECTIVES: Patients with end-stage kidney disease face an extremely high risk of major adverse cardiovascular and cerebrovascular events. This study investigated the role of microRNA-26a in patients with end-stage kidn

Y Yuanfang Li

The challenge of cell death switching in inflammasome-targeted therapies for bacterial and viral infections

Commun Biol. 2026 Jun 10;9(1):786. doi: 10.1038/s42003-026-10475-7.ABSTRACTInflammasome activation and pyroptosis are central to innate immune responses and play either protective or detrimental roles in host defense. Inhibiting these processes holds significant therapeutic promise for diseases exac

Y Yanfeng Li

Small Vesicles Big Impact: Exosomes in the Landscape of Women's Health

Pharm Res. 2026 Jun 10. doi: 10.1007/s11095-026-04133-0. Online ahead of print.ABSTRACTExtracellular vesicles (EVs), particularly exosomes, are small membrane-bound vesicles that mediate intercellular communication by transferring bioactive molecules such as proteins, lipids, and nucleic acids. Incr

V Vibhuti Agrahari

Mutation-dependent responses to sleep and exercise in clonal haematopoiesis

Clonal haematopoiesis (CH) activates inflammation and increases the risk of atherosclerosis^(1,2). Whether lifestyle alters CH clone expansion or the phenotypic programming of CH mutant cells, thereby affecting atherosclerosis, is unknown. Here, in humans and mice and across mutations in Jak2, Tet2,

T Teresa Gerhardt

Mitochondria directly interact with the nuclear pore complex

Nature. 2026 Jun 10. doi: 10.1038/s41586-026-10588-3. Online ahead of print.ABSTRACTMitochondria regulate cellular processes through direct and indirect interactions with other organelles. A well-studied example has been contact with the endoplasmic reticulum at mitochondrial-associated endoplasmic

I Ivan Menendez-Montes

Behavioral Components of Life's Essential 8 Are More Strongly Associated with Cognitive Function than Clinical Factors in Chinese Older Adults

Int J Behav Med. 2026 Jun 10. doi: 10.1007/s12529-026-10473-3. Online ahead of print.ABSTRACTBACKGROUND: Cardiovascular health is increasingly recognized as a key determinant of cognitive aging. The American Heart Association recently introduced Life's Essential 8 (LE8), integrating both behavioral

Q Qin Wang

Effects of Di(2-ethylhexyl) phthalate (DEHP) and hyperoxia on cardiovascular development in newborn rats

Pediatr Res. 2026 Jun 10. doi: 10.1038/s41390-026-05119-9. Online ahead of print.ABSTRACTBACKGROUND: Preterm infants encounter DEHP through medical devices and equipment. While hyperoxia is known to promote cardiac remodeling and dysfunction, the impact of early phthalate exposure is understudied. W

F Fatima Toor

Weight status, heart rate variability and quality-of-life in children with obstructive sleep apnea

Pediatr Res. 2026 Jun 10. doi: 10.1038/s41390-026-05079-0. Online ahead of print.ABSTRACTBACKGROUND: Pediatric obstructive sleep apnea (OSA) is associated with autonomic dysfunction and impaired quality-of-life (QoL). This study investigated whether weight status modifies the impact of OSA severity

L Li-Ang Lee

Autonomic impairment in advanced heart-failure patients revealed by nonlinear heart rate variability measured during exercise

Sci Rep. 2026 Jun 10. doi: 10.1038/s41598-026-50905-4. Online ahead of print.ABSTRACTAdvanced heart failure is characterized by profound autonomic dysfunction, yet resting measures of heart rate variability (HRV) provide limited insight into autonomic adaptability under physiological stress. We inve

S Salvatore Castelbuono

Effect of ZeeFree algorithm on the reduction of stair-step artifacts for coronary computed tomography angiography

Sci Rep. 2026 Jun 10. doi: 10.1038/s41598-026-53546-9. Online ahead of print.ABSTRACTStair-step artifacts is a common type of artifacts in the sequential scanning of CCTA and severely affects the image quality of coronary artery scans. This study aims to evaluate a novel algorithm for the removal of

X Xing Guo

Hybrid vision transformer and ensemble machine learning framework for automated atherosclerotic plaque classification in intravascular ultrasound imaging

Sci Rep. 2026 Jun 10. doi: 10.1038/s41598-026-53077-3. Online ahead of print.ABSTRACTAtherosclerotic plaque classification in intravascular ultrasound (IVUS) imaging is crucial for cardiovascular disease diagnosis and treatment planning. This paper proposes a novel hybrid framework that combines Vis

H Hazim Sheet Jasem

Bioresorbable electrochemical sensors for continuous deep-tissue lactate monitoring in critical care

Nat Commun. 2026 Jun 10. doi: 10.1038/s41467-026-74248-w. Online ahead of print.ABSTRACTLactate is a key metabolite and prognostic biomarker, reflecting oxygen delivery, cellular demand, and mitochondrial function. Current clinical lactate monitoring, however, relies on intermittent blood sampling,

C Chen Hu

Histaminylation alters collagen matrix mechanics and attenuates cardiac fibrosis post-myocardial infarction via mechanotransduction signaling axis

Signal Transduct Target Ther. 2026 Jun 11;11(1):229. doi: 10.1038/s41392-026-02721-5.ABSTRACTHistaminylation is a newly discovered monoaminylation catalyzed by transglutaminase 2 (TGM2), and its role in myocardial fibrosis has not yet been elucidated. Here, we identified histaminylation in cardiac t

J Jianfu Zhu

Dietary intake, fatty acid in adipose tissue and cardio-metabolic health: cross-sectional study from the TwinsUK cohort

Nutr Diabetes. 2026 Jun 10. doi: 10.1038/s41387-026-00438-6. Online ahead of print.ABSTRACTBACKGROUND: Subcutaneous adipose tissue, the largest fat depot buffering fatty acids, correlates with cardio-metabolic diseases. Diet plays a major role in fatty acid metabolism and correlates with cardio-meta

X Xinyu Yan

Persistent gaps in management and risk factor control among patients with atherosclerotic cardiovascular disease: All of us research program

Atherosclerosis. 2026 Jun 11:120794. doi: 10.1016/j.atherosclerosis.2026.120794. Online ahead of print.ABSTRACTBACKGROUND: Contemporary guidelines recommend aggressive low-density lipoprotein cholesterol (LDL-C) lowering in patients with atherosclerotic cardiovascular disease (ASCVD), yet significan

Y Yakubu Bene-Alhasan

Hemodynamic decoding for multimodal connected cardiovascular healthcare

No abstractSci Bull (Beijing). 2026 May 28:S2095-9273(26)00593-1. doi: 10.1016/j.scib.2026.05.065. Online ahead of print.NO ABSTRACTPMID:42270513 | DOI:10.1016/j.scib.2026.05.065

Y Yun Ke

Risk factors for atherosclerotic plaque formation in MASLD patients: insights from cross-sectional and Mendelian randomization analyses

Nutr Metab Cardiovasc Dis. 2026 May 30:104815. doi: 10.1016/j.numecd.2026.104815. Online ahead of print.ABSTRACTBACKGROUND AND AIM: Metabolic dysfunction-associated steatotic liver disease (MASLD) is a major contributor to chronic liver disease worldwide, yet the risk factors for carotid plaque in M

W Wei-Hao Peng

Plasma-based low-grade inflammation and endothelial dysfunction explain a small but significant proportion of the association between the n-3 polyunsaturated fatty acids and cardiovascular diseases: The Maastricht Study

J Clin Lipidol. 2026 May 25:S1933-2874(26)00366-1. doi: 10.1016/j.jacl.2026.05.228. Online ahead of print.ABSTRACTBACKGROUND: n-3 polyunsaturated fatty acids (PUFAs) are linked to lower cardiovascular disease (CVD) risk, potentially via reduced low-grade inflammation (LGI).OBJECTIVE: To examine whet

E Elena C Tore

Lifestyle and pharmacologic interventions for adults with hypertriglyceridemia: Critical to reduce risk of ASCVD and pancreatitis but often underutilized

J Clin Lipidol. 2026 May 26:S1933-2874(26)00359-4. doi: 10.1016/j.jacl.2026.05.224. Online ahead of print.ABSTRACTThe 2026 American College of Cardiology (ACC)/American Heart Association (AHA)/Multisociety Guideline on the Management of Dyslipidemia (2026 Guideline) replaces the 2018 AHA/ACC/Multiso

C Carol F Kirkpatrick

ATP Inside and Out: Understanding Atherosclerosis Through Energy Metabolism and Purinergic Signaling

J Atheroscler Thromb. 2026 Jun 11. doi: 10.5551/jat.RV22054. Online ahead of print.ABSTRACTAdenosine triphosphate (ATP) is well known as the major intracellular energy carrier. It also functions as a potent extracellular signaling molecule. In atherosclerosis, both intracellular and extracellular AT

O Osamu Baba

Distribution of Lipoprotein(a) Levels Among Children with Elevated Low-Density Lipoprotein Cholesterol Identified Through Universal Pediatric Lipid Screening

J Atheroscler Thromb. 2026 Jun 11. doi: 10.5551/jat.66114. Online ahead of print.ABSTRACTAIM: Children with elevated low-density lipoprotein cholesterol (LDL-C) levels, suspected familial hypercholesterolemia (FH), and elevated lipoprotein(a) (Lp(a)) levels are considered to have a particularly high

R Ryosuke Tani

Impact of Attenuation Threshold Selection on the Quantification of Carotid Calcification on CTA

AJNR Am J Neuroradiol. 2026 Jun 10:ajnr.A9468. doi: 10.3174/ajnr.A9468. Online ahead of print.ABSTRACTBACKGROUND: Carotid artery calcification is commonly assessed on computed tomography angiography (CTA) using a threshold of ≥130 Hounsfield units (HU), yet this may overestimate its volume and merge

J Juul Bierens

Real-World Data on the Efficacy and Safety of Fexuprazan in Patients with Gastroesophageal Reflux Disease: Interim Analysis of Post-Marketing Surveillance

Gut Liver. 2026 Jun 10. doi: 10.5009/gnl250427. Online ahead of print.ABSTRACTBACKGROUND/AIMS: Fexuprazan, a novel potassium-competitive acid blocker, has emerged as a promising alternative to proton pump inhibitors for the treatment of gastroesophageal reflux disease (GERD). Although its efficacy h

J Jie-Hyun Kim

Optimal 24-hour movement behaviour compositions across trimesters and risk of hypertensive disorders of pregnancy: the Pregnancy 24/7 cohort study

Br J Sports Med. 2026 Jun 10:bjsports-2025-111091. doi: 10.1136/bjsports-2025-111091. Online ahead of print.ABSTRACTOBJECTIVES: Hypertensive disorders of pregnancy (HDP) are primary antecedents of maternal cardiovascular morbidity during and after pregnancy. Despite evidence that 24-hour movement be

K Kara Whitaker