Endothelial Nuclear and Cytoskeletal Responses to Mechanical Stresses

Adv Exp Med Biol. 2026;1512:105-125. doi: 10.1007/978-3-032-22285-5_5.ABSTRACTThe ability of vascular endothelium to sense and respond to the mechanical stimuli generated by blood flow is pivotal in maintaining arterial homeostasis. A steady laminar flow tends to provide atheroprotective effect via

J Julie Y Ji

Vascular Mechanobiology: From Membrane to Nucleus

Adv Exp Med Biol. 2026;1512:85-104. doi: 10.1007/978-3-032-22285-5_4.ABSTRACTThe vascular wall is continuously exposed to complex hemodynamic forces in vivo due to blood flow. Endothelial cells (ECs) and vascular smooth muscle cells (VSMCs) experience distinct mechanical stresses, primarily shear st

Q Qing-Ping Yao

Cardiac unloading models for myocardial reverse remodeling

Basic Res Cardiol. 2026 Jul 8. doi: 10.1007/s00395-026-01196-3. Online ahead of print.ABSTRACTMyocardial reverse remodeling (RR) represents the structural, functional, cellular, and molecular recovery of the failing heart, leading to long-term prognostic improvements. This process can be mediated by

X Xinjie Xu