Implementing a Multi-Ancestry Polygenic Risk Score for Coronary Heart Disease in a Diverse Cohort

Genet Med. 2026 Jul 11:102662. doi: 10.1016/j.gim.2026.102662. Online ahead of print.ABSTRACTPURPOSE: We describe a prospective cohort study (NCT05277116) conducted in phase IV of the electronic MEdical Records and GEnomics (eMERGE) Network to implement a multi-ancestry polygenic risk score for coro

M Marwan Hamed

Clonal hematopoiesis of indeterminate potential (CHIP)-a pivotal contributor of aging and related disorders

Ann Transl Med. 2026 Jun 30;14(3):34. doi: 10.21037/atm-2026-1-0030. Epub 2026 Jun 29.ABSTRACTAging is associated with organ and tissue function deterioration and consequent increased risk of disease occurrence and mortality. Recent scientific advancements have succeeded in increasing the human life

A Ankita Dhenge

Predictors of Cerebral Small-Vessel Disease in Middle-Aged, Virologically Controlled People Living With HIV

Open Forum Infect Dis. 2026 Jun 29;13(7):ofag382. doi: 10.1093/ofid/ofag382. eCollection 2026 Jul.ABSTRACTBACKGROUND: Despite durable viral suppression with antiretroviral therapy (ART), non-AIDS comorbidities remain frequent in aging people with HIV (PWH). Cerebral small-vessel disease (CSVD), a ma

A Antoine Moulignier

Symptoms and causes of obstacles in AI-based telemonitoring: strategies for system development through a CRISP-DM lens

Front Artif Intell. 2026 Jun 26;9:1850272. doi: 10.3389/frai.2026.1850272. eCollection 2026.ABSTRACTINTRODUCTION: Chronic diseases, particularly heart failure (HF), impose a substantial clinical and socioeconomic burden worldwide. AI-based telemonitoring holds significant promise for improving chron

S Sophie Haas

Deep learning for cardiovascular disease: a comprehensive review of detection and risk forecasting

Front Artif Intell. 2026 Jun 26;9:1840804. doi: 10.3389/frai.2026.1840804. eCollection 2026.ABSTRACTThe biggest health threat to the global population is cardiovascular disease (CVD), which afflicts almost one-third of the global population and causes considerable monetary and social losses. Risk an

N N Ganeshan

Creation of a Standardized Myocardial Perfusion Single-photon Emission Computed Tomography Database to Enhance Coronary Artery Disease Research

J Med Signals Sens. 2026 Jun 1;16:16. doi: 10.4103/jmss.jmss_104_25. eCollection 2026.ABSTRACTBACKGROUND: Coronary artery disease (CAD) remains the leading global cause of cardiovascular mortality. Although single-photon emission computed tomography (SPECT) myocardial perfusion imaging (MPI) is wide

A Abdurrahim Rahimian

Progression of Metabolic Dysfunction-Associated Steatohepatitis in US Adults Using Linked Records and Claims

Gastro Hep Adv. 2026 Jun 10;5(9):101031. doi: 10.1016/j.gastha.2026.101031. eCollection 2026.ABSTRACTBACKGROUND AND AIMS: Metabolic dysfunction-associated steatohepatitis (MASH) affects approximately 5% of adults globally and, without effective treatment, may progress to end-stage liver disease (ESL

Y Yestle Kim

Microbiota-mediated mechanisms of natural products in atherosclerosis: focus on metabolic and inflammatory pathways

Front Endocrinol (Lausanne). 2026 Jun 26;17:1818349. doi: 10.3389/fendo.2026.1818349. eCollection 2026.ABSTRACTBACKGROUND: Atherosclerosis (AS) is a chronic inflammatory vascular disease characterized by lipid accumulation, endothelial dysfunction, immune dysregulation, and plaque formation. Beyond

Q Qi Shen

Retraction: Comparison of triglyceride-glucose index and triglyceride-glucose related indexes in predicting cardiovascular disease incidence among populations with cardiovascular-kidney-metabolic syndrome stages 0-3: a nationwide prospective cohort study

Front Endocrinol (Lausanne). 2026 Jun 26;17:1912913. doi: 10.3389/fendo.2026.1912913. eCollection 2026.ABSTRACT[This retracts the article DOI: 10.3389/fendo.2025.1562135.].PMID:42434298 | PMC:PMC13352155 | DOI:10.3389/fendo.2026.1912913

F Frontiers Editorial Office

The liver-brain axis, from its function to preventive therapeutic strategies in diseases

Front Endocrinol (Lausanne). 2026 Jun 26;17:1858091. doi: 10.3389/fendo.2026.1858091. eCollection 2026.ABSTRACTThe liver-brain axis (LBA) represents a bidirectional communication network between the liver and the central nervous system (CNS), governed by integrated neural, humoral, and immune signal

Y Yaoyao Chen

Use of epinephrine combined with dental anesthetics in hypertensive patients during dental treatment

J Clin Exp Dent. 2026 Apr 25;18(5):e600-e604. doi: 10.4317/jced.63825. eCollection 2026 Apr.ABSTRACTBACKGROUND: The use of local anesthetics containing epinephrine is routine in dental practice, although concerns persist regarding their safety in patients with cardiovascular disease.MATERIAL AND MET

A Alan Garcia Essado

Liver stiffness measured by transient elastography is not predictive of mortality or adverse events in adult patients with Fontan associated liver disease

Int J Cardiol Congenit Heart Dis. 2026 Jun 22;25:100693. doi: 10.1016/j.ijcchd.2026.100693. eCollection 2026 Sep.ABSTRACTBACKGROUND: Fontan associated liver disease (FALD) is a known complication in adult patients with total cavo-pulmonary connection. The relationship between the severity of FALD an

E Elettra Pomiato

Validation and implementation of ambulatory obstructive sleep apnea polygraphy screening combined with wearable semi-continuous heart rhythm monitoring in patients with atrial fibrillation: a validation and a pilot study

Front Cardiovasc Med. 2026 Jun 26;13:1873057. doi: 10.3389/fcvm.2026.1873057. eCollection 2026.ABSTRACTBACKGROUND: Obstructive sleep apnea (OSA) is a prevalent yet underdiagnosed risk factor in atrial fibrillation (AF) patients and may influence AF burden. Systematic OSA screening and long-term non-

A Anouk Delaet

Red cell distribution width: a novel and accessible predictor for immune checkpoint inhibitor-associated myocarditis-a retrospective cohort study

Front Cardiovasc Med. 2026 Jun 26;13:1737093. doi: 10.3389/fcvm.2026.1737093. eCollection 2026.ABSTRACTBACKGROUND: Immune checkpoint inhibitor (ICI)-associated myocarditis is a rare but potentially fatal immune-related adverse event characterized by high mortality and the absence of specific diagnos

S Shili Zhong

Plasma metabolic profiling reveals exploratory metabolic differences in chronic coronary syndrome with coronary artery calcification

Front Cardiovasc Med. 2026 Jun 26;13:1741496. doi: 10.3389/fcvm.2026.1741496. eCollection 2026.ABSTRACTBACKGROUND/OBJECTIVES: Coronary artery calcification (CAC) is a specific marker of coronary atherosclerotic heart disease, with chronic coronary syndrome (CCS) being a primary clinical manifestatio

X Xiaoxue Ding

Lactylation: a metabolic-epigenetic driver in atherosclerosis pathogenesis and therapeutic targeting

Front Cardiovasc Med. 2026 Jun 26;13:1790479. doi: 10.3389/fcvm.2026.1790479. eCollection 2026.ABSTRACTAtherosclerosis (AS), a disease of large and medium-sized arteries, is a common cause of cardiovascular morbidity and mortality. Lactylation is a recently identified post-translational modification

W Wenbo Lv

Editorial: HDL and cardiovascular disease: mechanisms, clinical relevance, and therapeutic impacts

No abstractFront Cardiovasc Med. 2026 Jun 26;13:1910207. doi: 10.3389/fcvm.2026.1910207. eCollection 2026.NO ABSTRACTPMID:42434140 | PMC:PMC13350449 | DOI:10.3389/fcvm.2026.1910207

J Jiayou Wang

Zebrafish as a translational platform for investigating multi-organ pharmacological interactions of traditional Chinese medicine

Front Pharmacol. 2026 Jun 26;17:1785275. doi: 10.3389/fphar.2026.1785275. eCollection 2026.ABSTRACTThe advancement of Traditional Chinese Medicine (TCM) requires model systems capable of dissecting its multi-component, multi-target pharmacology in a rapid and systematic manner. This review presents

J Jianhua Guo

The Role of Fish Oil in Modulating Metabolic Disorders: Implications for Cardiovascular Health, Endothelial Dysfunction Biomarkers, and Hypercholesterolemia

Int J Prev Med. 2026 May 29;17:38. doi: 10.4103/ijpvm.ijpvm_71_25. eCollection 2026.ABSTRACTBACKGROUND: Hypercholesterolemia is a significant risk factor for various metabolic disorders, such as diabetes, cardiovascular disease (CVD), and atherosclerosis, which contribute to morbidity and mortality

H Hessah M Al-Muzafar

Prevalence of Systemic Diseases in Patients Attending a Dental Clinic. A cross-sectional study

J Clin Exp Dent. 2026 May 29;18(6):e750-e756. doi: 10.4317/jced.63930. eCollection 2026 May.ABSTRACTBACKGROUND: It is crucial to identify the diseases and chronic conditions affecting patients attending a dental clinic, particularly in the field of oral surgery. Dentists must be provided with this i

C Carmen López-Carriches

A multi-factorial analysis of hypotension after intubation for patients with hypertensive intracerebral hemorrhage

Front Med (Lausanne). 2026 Jun 26;13:1843544. doi: 10.3389/fmed.2026.1843544. eCollection 2026.ABSTRACTOBJECTIVE: To investigate what factors predispose patients with hypertensive intracerebral hemorrhage to develop hypotension after intubation, and to use this knowledge to direct treatment efforts

W Wankang Dian

Stress-Induced (Takotsubo) Cardiomyopathy Associated With Upadacitinib Induction Therapy in Severe Crohn's Disease

ACG Case Rep J. 2026 Jul 10;13(7):e02236. doi: 10.14309/crj.0000000000002236. eCollection 2026 Jul.ABSTRACTJanus kinase inhibitors (JAKi) carry a class-wide boxed warning for major adverse cardiovascular events; however, stress-induced cardiomyopathy has not been previously reported with upadacitini

A Akram Alnounou

Gene silencing versus protein stabilization in transthyretin amyloid cardiomyopathy: contextualizing the HELIOS-B results and the road to precision agent selection

Ann Med Surg (Lond). 2026 Jun 9;88(7):4763-4764. doi: 10.1097/MS9.0000000000005215. eCollection 2026 Jul.ABSTRACTTransthyretin amyloid cardiomyopathy (ATTR-CM) now has three approved disease-modifying agents: tafamidis, acoramidis, and vutrisiran, representing two mechanistically distinct classes: T

S Sarum Ali Khan

Efficacy and safety of obicetrapib in patients at high cardiovascular risk: a systematic review, meta-analysis, and meta-regression

Ann Med Surg (Lond). 2026 Jun 17;88(7):4475-4486. doi: 10.1097/MS9.0000000000005091. eCollection 2026 Jul.ABSTRACTBACKGROUND: Dyslipidemia, particularly elevated low-density lipoprotein cholesterol (LDL-C), is a major risk factor for atherosclerotic cardiovascular disease (ASCVD). Despite statin the

S Sumet Kumar