Aging Dis. 2026 Apr 24. doi: 10.14336/AD.2025.1557. Online ahead of print.ABSTRACTInflammaging refers to the chronic, low-grade, sterile inflammatory state that emerges as a hallmark of biological aging and is increasingly recognized as a contributor to functional decline, frailty, and the progressi
Aging Dis. 2026 Apr 29. doi: 10.14336/AD.2025.1556. Online ahead of print.ABSTRACTAging is the predominant risk factor for several chronic disorders; therefore, elucidating the molecular and cellular mechanisms underlying age-related pathologies is essential for therapeutic advancement. Micheliolide
Neurogenetics. 2026 May 1;27(1):35. doi: 10.1007/s10048-026-00905-3.ABSTRACTHereditary cerebral small vessel disease (CSVD) associated with duplication involving region 13q34, which includes both COL4A1/COL4A2 is relatively rare. Here, we report a Japanese family with this duplication along with dil
Geroscience. 2026 May 1. doi: 10.1007/s11357-026-02272-1. Online ahead of print.ABSTRACTAging is a major risk factor for chronic diseases. Unlike the general population, members of long-lived families maintain exceptional health as they age, with over 10 years delayed onset of their first chronic di
FASEB J. 2026 May 15;40(9):e71786. doi: 10.1096/fj.202504826R.ABSTRACTNeonatal hypoxic-ischemic encephalopathy (NHIE) is a leading cause of morbidity and mortality in term infants. The anesthetic dexmedetomidine (Dex) has been shown to reduce brain damage. In this study, hypoxia-ischemia (HI) in neo
Naunyn Schmiedebergs Arch Pharmacol. 2026 May 1. doi: 10.1007/s00210-026-05404-8. Online ahead of print.ABSTRACTAstragaloside IV (AS-IV), a compound extracted from Radix Astragali, has been shown to have beneficial effects on cardiovascular disease. However, the role of AS-IV in cardiac toxicity cau
Eur J Pediatr. 2026 May 1;185(5):332. doi: 10.1007/s00431-026-07008-z.ABSTRACTKawasaki disease (KD) is an acute, immune-mediated medium-vessel vasculitis and the leading cause of acquired heart disease in children, yet its underlying etiology remains only partially defined. Emerging evidence implica
Cell Mol Life Sci. 2026 May 1. doi: 10.1007/s00018-026-06229-7. Online ahead of print.ABSTRACTHypertension is increasingly recognized as a contributor to intestinal barrier disruption and gut microbiota dysbiosis, thereby promoting systemic inflammation and end-organ damage. Sirtuin 7 (SIRT7), a nic
Mayo Clin Proc. 2026 Apr 30:S0025-6196(26)17386-8. doi: 10.1016/j.mayocp.2026.02.002. Online ahead of print.ABSTRACTOBJECTIVE: To evaluate the prognostic value of N-terminal pro-B-type natriuretic peptide (NT-proBNP) across different heart failure phenotypes in patients with chronic kidney disease (
JACC Case Rep. 2026 Mar 28:107653. doi: 10.1016/j.jaccas.2026.107653. Online ahead of print.ABSTRACTBACKGROUND: Regular physical activity confers substantial cardiovascular benefits, yet it may in rare cases precipitate sudden cardiac arrest (SCA) or sudden cardiac death (SCD) in predisposed individ
CONCLUSIONS: This study demonstrated that Selebeta^(®) PR is an effective and well-tolerated treatment for adults with OAB, with no clinically meaningful increase in blood pressure and a low incidence of adverse events.Investig Clin Urol. 2026 May;67(3):273-280. doi: 10.4111/icu.20250489.ABSTRACTPUR
Health Phys. 2026 May 1. doi: 10.1097/HP.0000000000002156. Online ahead of print.ABSTRACTMedical workers represent the largest occupationally exposed population to ionizing radiation, yet traditional radiation protection management often operates in departmental silos. This study aimed to develop an
CONCLUSION: Quantitative MBF and MFR estimates from ^(13)N-ammonia PET show good overall agreement across commonly used software tools but remain strongly dependent on kinetic model selection. These findings indicate that quantitative results are not directly interchangeable across different softwar
Wound Repair Regen. 2026 May-Jun;34(3):e70164. doi: 10.1111/wrr.70164.ABSTRACTDespite advancements in treatment, diabetic foot ulcers (DFU) are challenging to heal, and the comparative efficacy of debridement strategies is poorly understood. This study assessed the effectiveness and ranked debrideme
J Infus Nurs. 2026 May-Jun 01;49(3):149-161. doi: 10.1097/NAN.0000000000000639. Epub 2026 May 8.ABSTRACTPeripherally inserted central catheters (PICCs) are vital for long-term intravenous therapy but increase the risk of venous thromboembolism (VTE), a process commonly explained through the conceptu
Environ Sci Technol. 2026 May 1. doi: 10.1021/acs.est.5c17915. Online ahead of print.ABSTRACTHeatwaves, intensified by climate change and urban heat islands, pose a severe threat to global public health, particularly in densely populated cities. While the cooling effect of urban green spaces is reco
Chem Commun (Camb). 2026 May 1. doi: 10.1039/d5cc07262j. Online ahead of print.ABSTRACTEmerging from liposomes, nanomedicines have been rapidly developed into powerful tools for the diagnosis, therapy, and prevention of diseases. After bypassing from physiological barriers, most nanoparticles are in
A A Pract. 2026 May 1;20(5):e02198. doi: 10.1213/XAA.0000000000002198. eCollection 2026 May 1.ABSTRACTIntravenous leiomyomatosis (IVL) is a rare benign smooth muscle tumor that can extend into the heart, posing major anesthetic challenges. We report a 57-year-old woman with IVL extending from the ut
A A Pract. 2026 May 4;20(5):e02204. doi: 10.1213/XAA.0000000000002204. eCollection 2026 May 1.ABSTRACTUltrasound-guided left-sided or bilateral stellate ganglion block (SGB) has emerged as an effective bedside intervention for malignant ventricular arrhythmias (VA) refractory to conventional therapi
A A Pract. 2026 May 1;20(5):e02201. doi: 10.1213/XAA.0000000000002201. eCollection 2026 May 1.ABSTRACTSevere mitral stenosis (MS) during pregnancy represents a fixed cardiac output state and poses major anesthetic challenges during elective cesarean delivery (CD). Conventional single-shot spinal ane
Nurs Res. 2026 May 1. doi: 10.1097/NNR.0000000000000915. Online ahead of print.ABSTRACTBACKGROUND: Cardiovascular disease (CVD) is a major complication in patients with metabolic syndrome (MetS). The risk of CVD is influenced by genetic, sociodemographic, and lifestyle factors.OBJECTIVE: The aims of
J Med Eng Technol. 2026 May 1:1-44. doi: 10.1080/03091902.2026.2659912. Online ahead of print.ABSTRACTAortic valve (AV) disease is a major contributor to cardiovascular morbidity, particularly in ageing populations. Although surgical and transcatheter AV replacement are established treatments, no cu
J Clin Invest. 2026 May 1;136(9):e204459. doi: 10.1172/JCI204459. eCollection 2026 May 1.ABSTRACTFatty acid oxidation (FAO) provides the healthy heart with 60%-90% of its ATP, with the remainder coming from metabolism of glucose. Metabolic flexibility is key to heart function, ensuring an uninterrup
J Clin Invest. 2026 May 1;136(9):e202528. doi: 10.1172/JCI202528. eCollection 2026 May 1.ABSTRACTCardiomyocytes primarily rely on fatty acid oxidation (FAO), which provides more than 70% of their energy. However, excessive FAO can disrupt cardiac metabolism by increasing oxygen demand and suppressin
