Activation of HIF2 in Cardiac Vasculature Leads to Arterial Remodeling, Dilation, Thrombosis, and Inflammation, Recapitulating Cardiac Involvement in Kawasaki Disease

Circulation. 2026 Jun 8. doi: 10.1161/CIRCULATIONAHA.125.076230. Online ahead of print.ABSTRACTBACKGROUND: Global Vhl knockout results in vascular defects and early lethality, limiting our knowledge of von Hippel-Lindau/HIF (hypoxia-inducible factor) signaling in coronary vessel formation and homeos

B B Escobar

Digital biomarkers in chronic disease management: a systematic review of personalization and ethical challenges

Per Med. 2026 Jun 8:1-21. doi: 10.1080/17410541.2026.2682847. Online ahead of print.ABSTRACTINTRODUCTION: Chronic diseases remain leading contributors to global mortality, yet digital biomarkers offer transformative potential for personalized management. This systematic review evaluates the clinical

S Shrivats Manikandan

Performance of Polygenic Risk Scores for Atherosclerotic Cardiovascular Disease in the All of Us Program

Circ Genom Precis Med. 2026 Jun 8:e005382. doi: 10.1161/CIRCGEN.125.005382. Online ahead of print.ABSTRACTBACKGROUND: Performance and transferability of contemporary polygenic risk scores (PRS) for atherosclerotic cardiovascular disease phenotypes may vary across PRS methods, training data, and trai

J Johanna L Smith

Early menopause and cardiovascular disease risk: triangulating the evidence with a combined analysis

Climacteric. 2026 Jun 8:1-12. doi: 10.1080/13697137.2026.2675562. Online ahead of print.ABSTRACTOBJECTIVE: The relationship between early menopause and the risk of cardiovascular disease (CVD) is understudied in Asian women. This study aimed to investigate this association and its potential causalit

Y Yuru Wang

Assessing hemorrhagic risk in transthyretin cardiac amyloidosis. The haemorrhagic-embolic conundrum

No abstractAmyloid. 2026 Jun 8:1-4. doi: 10.1080/13506129.2026.2683425. Online ahead of print.NO ABSTRACTPMID:42253031 | DOI:10.1080/13506129.2026.2683425

S Silvia Vilches

Vascular Disease Prospective-Retrospective Observational Registry for Aortic Aneurysm and Peripheral Artery Disease in Korea: Study Rationale and Methodology

Vasc Specialist Int. 2026 Jun 8;42:22. doi: 10.5758/vsi.250144.ABSTRACTPURPOSE: Peripheral artery disease (PAD) and aortic aneurysm (AA) are major manifestations of systemic atherosclerosis. Although they differ in pathophysiology and clinical presentation, they share common risk factors and overlap

J Ju Yeon Choi

Prevalence of Cardiovascular Disease Risk Factors among Adults of Mulbagal in Rural South India: A Cross-sectional Study Using the WHO STEPS Approach

Ann Afr Med. 2026 Jun 5. doi: 10.4103/aam.aam_107_26. Online ahead of print.ABSTRACTBACKGROUND: Cardiovascular diseases (CVDs) are the leading global cause of mortality, disproportionately affecting low- and middle-income countries. Rural India is experiencing rising CVD risk factors, but high-quali

A Achal Shetty

Clinical management of complications after chronic spinal cord injury: a review of recent advances

Ann Med. 2026 Dec;58(1):2672277. doi: 10.1080/07853890.2026.2672277. Epub 2026 Jun 7.ABSTRACTINTRODUCTION: Chronic spinal cord injury (SCI) is a severe neurological disorder resulting from trauma or disease, characterized by persistent motor, sensory, and autonomic deficits below the level of the le

X Xingyu Zhao

Superoxide Dismutase-Centered Modulation by Curcumin in Cardiovascular Diseases: Mechanistic Insights and Translational Implications

J Cell Mol Med. 2026 Jun;30(11):e71233. doi: 10.1111/jcmm.71233.ABSTRACTCardiovascular diseases (CVD) remain the leading global cause of morbidity and mortality, driven in part by dysregulated redox homeostasis and chronic inflammation. Superoxide dismutase (SOD), a key enzymatic defence against rea

D Danial Khayatan

The Use of Statins in Parkinson's and Alzheimer's Disease: A 2021-2025 State-of-the-Art Review of Clinical and Preclinical Evidence

Pharmacol Res Perspect. 2026 Jun;14(3):e70280. doi: 10.1002/prp2.70280.ABSTRACTStatins, widely prescribed for cardiovascular prevention, have emerged as potential disease-modifying agents in neurodegenerative disorders due to their pleiotropic effects on cholesterol metabolism, neuroinflammation, ox

L Luigi Maria Chiatto

MYO6 and Heart: A Novel Variant in a Deaf Infant With Supraventricular Tachycardia

Mol Genet Genomic Med. 2026 Jun;14(6):e70244. doi: 10.1002/mgg3.70244.ABSTRACTBACKGROUND: Variants in MYO6 are well known causes of hereditary deafness and have occasionally been linked to cardiac abnormalities, including hypertrophic cardiomyopathy and prolonged QT interval. However, supraventricul

S Samira Kalayinia

Electrophysiological Characteristics of the Right Middle Pulmonary Vein and the Impact of Additional Carina Ablation

Pacing Clin Electrophysiol. 2026 Jun 7. doi: 10.1111/pace.70309. Online ahead of print.ABSTRACTBACKGROUND: Previous studies have demonstrated electrical connections between ipsilateral pulmonary veins (PVs). This study aimed to characterize the electrophysiological features of right middle pulmonary

Y Yue Qiu

Outcomes of Patients With High-Risk Plaques Treated With a Bioresorbable Magnesium Scaffold: Insights From the BIOMAG-I Study

Catheter Cardiovasc Interv. 2026 Jun 7. doi: 10.1002/ccd.70655. Online ahead of print.ABSTRACTBACKGROUND: Early identification and targeted treatment of coronary lesions at higher risk of future events remains a major unmet need in coronary artery disease research. Invasive treatment of such plaques

P Pablo M Rubio

Significance of echocardiographic metrics including TRV and TAPSE/SPAP in mild haemodynamic pulmonary hypertension - data from EVIDENCE-PAH UK

Echo Res Pract. 2026 Jun 8;13(1):20. doi: 10.1186/s44156-026-00119-1.ABSTRACTBACKGROUND: The 2022 ESC/ERS guidelines redefined pulmonary hypertension (PH) as a mean pulmonary artery pressure (mPAP) >20 mmHg on right heart catheterisation (RHC). Echocardiography, using metrics such as tricuspid regur

N Nina Karia

International practices and variability in right heart echocardiography: results from the RVNet(Work) international survey

Echo Res Pract. 2026 Jun 8;13(1):22. doi: 10.1186/s44156-026-00121-7.ABSTRACTBACKGROUND: The assessment of the right heart (RH) plays a central role in the diagnosis and management of cardiovascular and pulmonary diseases. Although current guidelines have improved standardization, there is anecdotal

H Harry Magunia

Predictive value of the triglyceride glucose index-a body shape index (TyG-ABSI) for cardiovascular disease and its comparison with other TyG-related obesity indices: a study based on the China health and retirement longitudinal study (CHARLS) cohort

Cardiovasc Diabetol. 2026 Jun 7. doi: 10.1186/s12933-026-03241-w. Online ahead of print.ABSTRACTBACKGROUND: Insulin resistance (IR) and obesity are recognized as major drivers of cardiovascular disease (CVD). The triglyceride-glucose index-a body shape index (TyG-ABSI), a novel metric integrating li

X Xinying Liu

Combination of GLP-1 receptor agonists and SGLT2 inhibitors in cardiometabolic disease: synergistic, additive, or non-additive effects? A narrative review

Cardiovasc Diabetol. 2026 Jun 7. doi: 10.1186/s12933-026-03239-4. Online ahead of print.ABSTRACTBACKGROUND: Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) and sodium-glucose cotransporter-2 inhibitors (SGLT2 inhibitors) are two novel classes of glucose-lowering agents with proven cardiometabo

E Eirini Stamouli

Smartwatch-derived exercise metrics as predictors of early hypertension: a prospective observational study

BMC Cardiovasc Disord. 2026 Jun 8. doi: 10.1186/s12872-026-06073-4. Online ahead of print.ABSTRACTBACKGROUND: Early identification of individuals at risk for hypertension is essential for effective cardiovascular disease. Physiological and activity metrics derived from consumer smartwatches may offe

E Esma Selva Ateş Ceyhun

Lipoprotein(a) and Peripheral Artery Disease as Independent Predictors of Arterial Stiffness in Patients With Hypertension: A Single-Center Cross-Sectional Study

J Clin Hypertens (Greenwich). 2026 Jun;28(6):e70309. doi: 10.1111/jch.70309.ABSTRACTCarotid-femoral pulse-wave velocity (cfPWV) is a marker of central arterial stiffness and an established predictor of cardiovascular risk in hypertension. Although elevated lipoprotein(a) [Lp(a)] concentrations and p

B Bibombe P Mwipatayi

Impact of guideline definitions on right ventricular diameter in echocardiography: an automated analysis in controls and patients with pulmonary hypertension

Echo Res Pract. 2026 Jun 8;13(1):21. doi: 10.1186/s44156-026-00118-2.ABSTRACTBACKGROUND: To improve standardization, the 2025 American Association of Echocardiography (ASE) guidelines revised the definitions of right ventricular (RV) basal and mid diameters, revising the 2010 ASE and European Societ

F Frida N Hermansson

Survodutide in adults with obesity and metabolic dysfunction-associated steatotic liver disease: SYNCHRONIZE-MASLD, a randomized, double-blind, placebo-controlled phase 3 trial

Nat Med. 2026 Jun 7. doi: 10.1038/s41591-026-04479-3. Online ahead of print.ABSTRACTSurvodutide is a glucagon receptor/glucagon-like peptide-1 receptor dual agonist under investigation for treating obesity and related diseases. The SYNCHRONIZE-MASLD phase 3, randomized, double-blind, placebo-control

L Lee M Kaplan

Role of Nrf2 and NQO1 genetic variants in cardiometabolic diseases: an 8-year prospective study of genetic, dietary, biochemical, and oxidative stress markers in Iranian Kurdish Adults

Sci Rep. 2026 Jun 7. doi: 10.1038/s41598-026-56799-6. Online ahead of print.ABSTRACTThis study assessed the association between Nrf2 (rs6721961) and NQO1 (rs1800566) polymorphisms and cardiometabolic diseases (CMDs) in the Kurdish population of Iran. We analyzed 509 Kurdish individuals. Biochemical

M Maryam Kohsari

Glycemic control and cardiovascular health in prediabetes: untiring exploration towards consensus

Zhonghua Yi Xue Za Zhi. 2026 Jun 9;106(21):2091-2095. doi: 10.3760/cma.j.cn112137-20260323-00777.ABSTRACTDiabetes-related cardiovascular diseases carry high rates of disability and mortality, and their medical costs are prohibitively expensive. Shifting management upstream is imperative. The risk of

G G W Li

Epidemiology of Cardiovascular Disease in Pregnancy in Japan - Analysis of a Nationwide Perinatal Database 2014-2023

Circ J. 2026 Jun 5. doi: 10.1253/circj.CJ-26-0154. Online ahead of print.ABSTRACTBACKGROUND: Cardiovascular disease (CVD) is an increasingly important contributor to maternal morbidity and mortality worldwide, but contemporary nationwide data in Japan remain limited.METHODS AND RESULTS: We conducted

M Masafumi Nii