Estimating Heart Failure Health Status From Multimodal Wearables: Implementation of a Feature-Engineering Framework for KCCQ-12 Prediction

Mayo Clin Proc Digit Health. 2026 Sep 17;4(4):100403. doi: 10.1016/j.mcpdig.2026.100403. eCollection 2026 Dec.ABSTRACTRoutine monitoring of symptom burden and quality of life in heart failure (HF) patients is limited by intermittent sampling of validated instruments, such as the Kansas City Cardiomy

C Christopher J McLeod

DNA methylation analysis of aortic wall tissue in ascending aortic dilatation/aneurysm and dissection

Vavilovskii Zhurnal Genet Selektsii. 2026 Oct;30(6):938-948. doi: 10.18699/vjgb-26-94.ABSTRACTAscending aortic dilatation/aneurysm and dissection are life-threatening cardiovascular conditions. However, the epigenetic regulatory mechanisms within aortic cells underlying these pathologies remain poor

I I A Goncharova

Tissue engineering polymeric formulations enable lymphangiogenesis for myocardial repair

Bioact Mater. 2026 Oct 12;68:1004-1022. doi: 10.1016/j.bioactmat.2026.08.048. eCollection 2027 Feb.ABSTRACTPURPOSE: Emerging evidence emphasizes the pivotal contribution of cardiac lymphatic activation following ischemic heart injury, with induced lymphangiogenesis driving edema resolution and infla

Z Zhuo Liu

Endovascular treatment versus best medical treatment for acute anterior cerebral artery occlusion: a single-center inverse probability of treatment-weighted cohort study

Front Neurol. 2026 Oct 7;17:1896249. doi: 10.3389/fneur.2026.1896249. eCollection 2026.ABSTRACTINTRODUCTION: Evidence regarding the benefit of endovascular treatment (EVT) for isolated acute anterior cerebral artery occlusion remains limited. We aimed to compare the efficacy and safety of EVT versus

X Xiaolin Wan

Higher fibrosis-4 index is associated with 2-year cardiovascular events in Vietnamese adults with type 2 diabetes mellitus: a prospective cohort study

Front Gastroenterol (Lausanne). 2026 Oct 7;5:1973311. doi: 10.3389/fgstr.2026.1973311. eCollection 2026.ABSTRACTBACKGROUND: Cardiovascular disease is a major extrahepatic outcome in type 2 diabetes mellitus (T2DM) and metabolic fatty liver disease, but prospective data integrating transient elastogr

Q Quoc Bao Vu

Antiplatelet therapy for primary prevention of stroke in patients with carotid web: a prospective cohort study

Front Neurol. 2026 Oct 7;17:1955675. doi: 10.3389/fneur.2026.1955675. eCollection 2026.ABSTRACTBACKGROUND: Carotid webs have emerged as an etiology for ischemic stroke in younger patients, with a high recurrence rate. However, the optimal prevention strategy for asymptomatic carotid webs remains unc

X Xiaomeng Wang

A machine learning-driven and explainable prediction model for in-hospital mortality in patients with diabetes mellitus and congestive heart failure: integrating XGBoost and SHAP approaches

Front Public Health. 2026 Oct 7;14:1951635. doi: 10.3389/fpubh.2026.1951635. eCollection 2026.ABSTRACTBACKGROUND: Patients with congestive heart failure (CHF) and type 2 diabetes mellitus (T2DM) are at elevated risk of in-hospital mortality, particularly in intensive care units (ICUs). Conventional

J Jingru Hu

Independent and joint associations of reported household chemical product use and overweight/obesity with cardiovascular disease among older adults in China: a national cross-sectional study

Front Nutr. 2026 Oct 7;13:1944461. doi: 10.3389/fnut.2026.1944461. eCollection 2026.ABSTRACTBACKGROUND: Household chemicals are common indoor exposures among older adults, but their association with cardiovascular disease (CVD) and whether the association varies according to body weight status remai

X Xiaojie Pan

Formononetin relieves chronic stress-related neointimal hyperplasia in mice by regulating HDAC6

Front Cardiovasc Med. 2026 Oct 7;13:1865656. doi: 10.3389/fcvm.2026.1865656. eCollection 2026.ABSTRACTINTRODUCTION: Chronic stress severely impairs physical and mental health and is a critical risk factor for cardiovascular diseases. Formononetin (FMN) has shown promising cardiovascular protective e

S Shanqian Li

Linking liver fibrosis to cardiac structure, function, and heart disease: a community-based fibrosis-4 index study

Front Cardiovasc Med. 2026 Oct 7;13:1777872. doi: 10.3389/fcvm.2026.1777872. eCollection 2026.ABSTRACTBACKGROUND: The Fibrosis-4 Index (FIB-4) is a non-invasive tool used to assess advanced liver fibrosis. Although liver fibrosis has been linked to heart disease, its relationship with cardiac struct

R Rongrong Yang

Association between radiotherapy laterality and cardiovascular disease mortality in male breast cancer patients receiving postoperative radiotherapy: a competing risks analysis and standardized mortality ratio assessment using SEER data

Front Cardiovasc Med. 2026 Oct 7;13:1857560. doi: 10.3389/fcvm.2026.1857560. eCollection 2026.ABSTRACTBACKGROUND: The association between radiotherapy (RT) laterality and cardiovascular disease (CVD) mortality in male breast cancer (MBC) remains unknown. We evaluated whether left-sided RT confers hi

J Jia Si

The long and winding road to diagnosis: diagnostic delays and healthcare utilization in patients with CFT-confirmed INOCA

Front Cardiovasc Med. 2026 Oct 7;13:1924728. doi: 10.3389/fcvm.2026.1924728. eCollection 2026.ABSTRACTBACKGROUND: Patients with Ischemia and No Obstructive Coronary Arteries (INOCA) experience recurrent angina, report reduced quality of life, and are at increased risk for major adverse cardiovascula

A Angela Wang

Hypertriglyceridemic waist-to-height ratio and the triple burden of hypertension, diabetes, and dyslipidemia in adults: association and network analysis

Front Endocrinol (Lausanne). 2026 Oct 7;17:1932657. doi: 10.3389/fendo.2026.1932657. eCollection 2026.ABSTRACTBACKGROUND: Hypertension, diabetes, and dyslipidemia frequently co-occur, yet simple screening tools are lacking in resource-limited settings. The hypertriglyceridemic waist-to-height ratio

L Lanqiqi Wu

Receiver operating characteristic-derived thresholds for early validation of myocardial injury in a rat ischemia-reperfusion model

Front Physiol. 2026 Oct 7;17:1923294. doi: 10.3389/fphys.2026.1923294. eCollection 2026.ABSTRACTBACKGROUND: Myocardial infarction (MI) is a major manifestation of cardiovascular disease and a leading cause of morbidity and mortality worldwide. In experimental research, rat ischemia-reperfusion (IR)

R Rani Wainer-Shlomo

Risk factors for postoperative recurrence of chronic subdural hematoma and construction and validation of an online dynamic nomogram prediction model

Front Neurol. 2026 Oct 7;17:1877761. doi: 10.3389/fneur.2026.1877761. eCollection 2026.ABSTRACTOBJECTIVE: To investigate factors associated with postoperative recurrence in patients with chronic subdural hematoma (CSDH) and to construct and internally validate an online dynamic nomogram for individu

X Xiangyu Zhang

Microregional RNA sequencing reveals layer-specific smooth muscle cell heterogeneity in human bicuspid aortic valve-associated aortic dilatation

JVS Vasc Sci. 2026 Sep 16;7:100444. doi: 10.1016/j.jvssci.2026.100444. eCollection 2026.ABSTRACTOBJECTIVE: Smooth muscle cells in the human ascending aorta exhibit layer-specific heterogeneity; however, their molecular profiles and contribution to aortic diseases remain poorly understood. In this st

S Shigeki Koizumi

Quality appraisal of clinical practice guidelines for fertility preservation in patients with breast cancer: a systematic review using AGREE II and AGREE-REX

Front Med (Lausanne). 2026 Oct 7;13:1930322. doi: 10.3389/fmed.2026.1930322. eCollection 2026.ABSTRACTOBJECTIVE: This review utilizes the AGREE II instrument to evaluate the methodological rigor and the AGREE-REX instrument to evaluate the implementability of recommendations within clinical practice

W Wenjuan Yan

Eosinophils, malignant brain edema, and functional outcome after mechanical thrombectomy: a mediation analysis

Front Neurol. 2026 Oct 7;17:1939369. doi: 10.3389/fneur.2026.1939369. eCollection 2026.ABSTRACTOBJECTIVE: To examine the independent associations of admission eosinophil count with malignant brain edema (MBE) and with poor 3-month functional outcome after mechanical thrombectomy (MT), and to quantif

H Haojun Lu

The mediating role of out-of-hospital adherence between health literacy and quality of life in Chinese stroke survivors: a cross-sectional study

Front Public Health. 2026 Oct 7;14:1917398. doi: 10.3389/fpubh.2026.1917398. eCollection 2026.ABSTRACTBACKGROUND: Stroke, the second foremost cause of mortality globally, imposes a considerable disease burden in China. Limited health literacy and difficulties adhering to post-discharge care may be a

H Hui Jun Sun

MGCF-Net: a multi-view granular-ball contrastive fusion network for spatial transcriptomics clustering

Front Physiol. 2026 Oct 7;17:1967219. doi: 10.3389/fphys.2026.1967219. eCollection 2026.ABSTRACTINTRODUCTION: Spatial domain identification from spatial transcriptomics (ST) data is essential for characterizing the spatial organization of complex tissues. Existing contrastive learning methods face a

L Li Zhu

Independent association of the CHG index with cardiometabolic multimorbidity: real-world evidence from community and clinical datasets

Front Public Health. 2026 Oct 7;14:1967131. doi: 10.3389/fpubh.2026.1967131. eCollection 2026.ABSTRACTBACKGROUND: Cardiometabolic multimorbidity (CMM) is an increasing public health challenge in aging populations. The cholesterol-high-density lipoprotein-glucose (CHG) index is an emerging metabolic

Z Zexu Cui

Prophylactic anticoagulation in isolated tumor thrombus: a single-center retrospective cohort study

Res Pract Thromb Haemost. 2026 Sep 11;10(6):106951. doi: 10.1016/j.rpth.2026.106951. eCollection 2026 Aug.ABSTRACTBACKGROUND: The optimal management of isolated tumor thrombus (TT) remains unknown. Although therapeutic anticoagulation is indicated for concurrent bland thrombosis or history of venous

L Loula Papageorgiou

Diagnostic accuracy of tongue diagnosis for stroke syndrome differentiation in traditional Chinese medicine: a systematic review, meta-analysis, and narrative synthesis of artificial intelligence-assisted models

Front Neurol. 2026 Oct 7;17:1874937. doi: 10.3389/fneur.2026.1874937. eCollection 2026.ABSTRACTBACKGROUND: Tongue examination is central to traditional Chinese medicine (TCM) syndrome differentiation after stroke, but its diagnostic accuracy has not been evaluated using contemporary diagnostic test

Y Yibo Huang

Conventional and novel hypoxemia-related indices for obstructive sleep apnea severity and incident hypertension: a prospective cohort study

Front Neurol. 2026 Oct 7;17:1973505. doi: 10.3389/fneur.2026.1973505. eCollection 2026.ABSTRACTBACKGROUND AND OBJECTIVE: Obstructive sleep apnea (OSA) is associated with hypertension (HTN), but the apnea-hypopnea index (AHI) and oxygen desaturation index (ODI) may not fully characterize nocturnal hy

L Lixia Wang