Cologne (Germany): Institute for Quality and Efficiency in Health Care (IQWiG); 2026 Feb 22.ABSTRACTRESEARCH QUESTION: The aim of this report is toassess the benefit of diagnostics using cardiac magnetic resonance imaging as part of a diagnostic strategy, compared with a diagnostic strategy without
JMA J. 2026 Jan 15;9(1):271-282. doi: 10.31662/jmaj.2025-0177. Epub 2025 Dec 5.ABSTRACTINTRODUCTION: Statins can treat dyslipidemia, but even if low-density lipoprotein decreases to target levels, high triglyceride (TG) levels may represent a residual risk. Therefore, we performed a crossover study
JMA J. 2026 Jan 15;9(1):24-37. doi: 10.31662/jmaj.2025-0397. Epub 2025 Dec 12.ABSTRACTAtherosclerosis, the leading cause of coronary artery disease, stroke, and peripheral arterial disease, is now recognized as a lipid-driven disease complicated by an immune response that plays a major role in its p
No abstractHepatobiliary Surg Nutr. 2026 Feb 1;15(1):24. doi: 10.21037/hbsn-2025-537. Epub 2026 Jan 21.NO ABSTRACTPMID:41676774 | PMC:PMC12887310 | DOI:10.21037/hbsn-2025-537
The sarco-endoplasmic reticulum Ca²⁺-ATPase (SERCA) is a ubiquitous P-type ATPase that restores cytosolic Ca ^(2+) to the sarco-endoplasmic reticulum. SERCA is essential for cardiac Ca ^(2+) cycling and cellular energy metabolism. Several small molecules enhance SERCA function and show promise in mo
Arch Med Sci. 2025 Dec 31;21(6):2229-2245. doi: 10.5114/aoms/216960. eCollection 2025.ABSTRACTThis state-of-the-art review surveys the rapidly advancing field of triglyceride-lowering therapies as of 2025, positioning hypertriglyceridemia (HTG) as both a residual driver of atherosclerotic cardiovasc
Arch Med Sci. 2025 Dec 20;21(6):2246-2257. doi: 10.5114/aoms/212635. eCollection 2025.ABSTRACTAtherosclerotic cardiovascular disease (ASCVD) is the leading cause of death in Poland. Lipoprotein(a) [Lp(a)] constitutes an independent, causal risk factor for ASCVD and aortic valve stenosis. Elevated Lp
No abstractArch Med Sci. 2025 Dec 23;21(6):2882-2887. doi: 10.5114/aoms/188090. eCollection 2025.NO ABSTRACTPMID:41676417 | PMC:PMC12887968 | DOI:10.5114/aoms/188090
IBRO Neurosci Rep. 2026 Jan 30;20:206-217. doi: 10.1016/j.ibneur.2026.01.014. eCollection 2026 Jun.ABSTRACTThe glymphatic system plays a critical role in clearing metabolic waste and neurotoxic proteins from the brain, and its dysfunction is implicated in neurodegenerative diseases such as Alzheimer
Eur Cardiol. 2026 Jan 21;21:e02. doi: 10.15420/ecr.2025.14. eCollection 2026.ABSTRACTThe emerging field of cardio-oncology has grown considerably over the past two decades. While the issue of myocardial cardiotoxicity has received the most attention, it is now recognised that cardio-oncology encompa
Eur Cardiol. 2026 Jan 21;21:e03. doi: 10.15420/ecr.2025.54. eCollection 2026.ABSTRACTBACKGROUND: Invasive coronary functional tests (I-CFTs) can identify the mechanism(s) of angina in patients with non-obstructed coronary arteries (ANOCA). In this study, we assessed whether non-invasive coronary fun
Front Pediatr. 2026 Jan 27;14:1682239. doi: 10.3389/fped.2026.1682239. eCollection 2026.ABSTRACTOBJECTIVE: Over the previous decade, fibroblast growth factor 23 (FGF23) has been identified as a key biomarker in the context of cardiovascular diseases(CVD). The primary goal of this investigation was t
Front Physiol. 2026 Jan 27;16:1704428. doi: 10.3389/fphys.2025.1704428. eCollection 2025.ABSTRACTAccurate prediction of asymptomatic small abdominal aortic aneurysm (AAA) growth is crucial for risk stratification and personalized surveillance. This study developed an end-to-end deep learning framewo
Am J Transl Res. 2026 Jan 15;18(1):222-235. doi: 10.62347/NFCT6486. eCollection 2026.ABSTRACTOBJECTIVES: To investigate the role of monocarboxylate transporter 4 (MCT4) in non-alcoholic fatty liver disease (NAFLD) and its underlying mechanisms.METHODS: Palmitic acid (PA) was used to stimulate L-02 c
Am J Transl Res. 2026 Jan 15;18(1):729-740. doi: 10.62347/AGWY9542. eCollection 2026.ABSTRACTAIMS: To investigate the association between circulating irisin levels, metabolic profiles, and clinical outcomes in obesity-associated atherosclerosis.METHODS: This retrospective study included 220 patients
Am J Transl Res. 2026 Jan 15;18(1):236-247. doi: 10.62347/UWCR7720. eCollection 2026.ABSTRACTOBJECTIVES: Patients with type 2 diabetes mellitus (T2DM) exhibit accelerated atherosclerosis progression and an increased risk of cardiovascular disease (CVD). Early CVD diagnosis and timely intervention ar
Am J Transl Res. 2026 Jan 15;18(1):664-675. doi: 10.62347/FYQI2511. eCollection 2026.ABSTRACTOBJECTIVE: To investigate the effects of complete revascularization on oxidative stress, blood pressure control, and prognosis in patients with acute myocardial infarction (AMI).METHODS: Clinical data from 8
Am J Transl Res. 2026 Jan 25;18(1):869-878. doi: 10.62347/UEKM4233. eCollection 2026.ABSTRACTOBJECTIVE: To evaluate the prognostic value of specific echocardiographic parameters, particularly myocardial strain indices, in patients with coronary heart disease (CHD) undergoing elective percutaneous co
Healthc Technol Lett. 2026 Feb 10;13(1):e70063. doi: 10.1049/htl2.70063. eCollection 2026 Jan-Dec.ABSTRACTAccurate and early detection of chronic heart disease is vital, as it remains one of the leading global causes of mortality. Despite advancements in Smart Healthcare 5.0 and modern information t
AME Case Rep. 2026 Jan 16;10:27. doi: 10.21037/acr-2025-220. eCollection 2026.ABSTRACTBACKGROUND: Acute empyema presents a significant mortality risk in advanced-age populations, with rates reaching up to 20% in patients over 80 years of age. While initial treatment typically involves antibiotics an
Front Immunol. 2026 Jan 27;17:1728509. doi: 10.3389/fimmu.2026.1728509. eCollection 2026.ABSTRACTCD36 is a multifunctional glycoprotein essential in fatty acid metabolism, angiogenesis, and atherogenesis, playing a critical role in immunological processes. This comprehensive review synthesizes curre
Front Immunol. 2026 Jan 27;17:1730089. doi: 10.3389/fimmu.2026.1730089. eCollection 2026.ABSTRACTSevere fever with thrombocytopenia syndrome (SFTS), caused by the SFTS virus (SFTSV), has emerged as a significant global public health threat. Infected patients may present with gastrointestinal, neurol
IMetaOmics. 2024 Oct 25;1(2):e33. doi: 10.1002/imo2.33. eCollection 2024 Dec.ABSTRACTTargeting gut flora to lower sickness risk is a growing scientific subject. The intricate network of microorganisms (gut microbiota) in the human intestines regulates many physiological systems and may be important
Indian J Thorac Cardiovasc Surg. 2026 Mar;42(3):390-396. doi: 10.1007/s12055-025-02088-2. Epub 2025 Nov 19.ABSTRACTCombined heart and liver transplantation (CHLT) is a rare, complex procedure for dual-organ failure. This report describes a 58-year-old male with ischemic cardiomyopathy and severe con
