J Mech Behav Biomed Mater. 2026 Jan 8;176:107340. doi: 10.1016/j.jmbbm.2026.107340. Online ahead of print.ABSTRACTElastic fibers are critical for proper mechanical function of large arteries such as the aorta. Fragmentation, degradation, or reduced amounts of elastic fibers are associated with aorti
Leg Med (Tokyo). 2026 Jan 10;80:102779. doi: 10.1016/j.legalmed.2026.102779. Online ahead of print.ABSTRACTMedial degeneration of the aortic wall represents a critical substrate for the development of acute aortic syndromes, particularly dissection, in both clinically healthy individuals and those w
Arch Cardiol Mex. 2026 Jan 12. doi: 10.24875/ACM.25000031. Online ahead of print.ABSTRACTCardiogenic shock refers to the reduction in cardiac output caused by myocardial dysfunction, which results in biochemical and clinical manifestations of hypoperfusion. It is mostly due to acute coronary syndrom
IEEE Rev Biomed Eng. 2026 Jan 12;PP. doi: 10.1109/RBME.2025.3644411. Online ahead of print.ABSTRACTMicrocirculation is essential for maintaining tissue health and overall physiological function. Over the past few decades, various optical techniques have been developed to measure, visualize, and asse
Neurology. 2026 Feb 10;106(3):e214574. doi: 10.1212/WNL.0000000000214574. Epub 2026 Jan 12.ABSTRACTBACKGROUND AND OBJECTIVES: Dementia risk prediction models developed for the general population perform poorly in stroke cohorts. Existing stroke-specific models are few and limited by short prediction
No abstractCirculation. 2026 Jan 13;153(2):e11. doi: 10.1161/CIR.0000000000001408. Epub 2026 Jan 12.NO ABSTRACTPMID:41525442 | DOI:10.1161/CIR.0000000000001408
No abstractCirculation. 2026 Jan 13;153(2):e6-e7. doi: 10.1161/CIRCULATIONAHA.125.076839. Epub 2026 Jan 12.NO ABSTRACTPMID:41525438 | DOI:10.1161/CIRCULATIONAHA.125.076839
Circulation. 2026 Jan 13;153(2):115-131. doi: 10.1161/CIRCULATIONAHA.125.075978. Epub 2026 Jan 12.ABSTRACTMany patients with severe aortic stenosis present with concomitant multivalvular heart disease. The management of this condition remains challenging and requires a multidisciplinary approach tha
QJM. 2026 Jan 12:hcag010. doi: 10.1093/qjmed/hcag010. Online ahead of print.ABSTRACTEnhanced external counterpulsation (EECP) is a non-invasive circulatory support device that has been shown to improve perfusion in cardiovascular diseases; however, its effectiveness in ischemic stroke is yet to be e
PLoS One. 2026 Jan 12;21(1):e0339455. doi: 10.1371/journal.pone.0339455. eCollection 2026.ABSTRACTCerebral ischemia-reperfusion injury (CCI) is a cause of neurological damage. Hyperbaric oxygen therapy (HBOT) can improve recovery in CCI in relation to iron metabolism and ferroptosis, but the precise
Am J Physiol Regul Integr Comp Physiol. 2026 Jan 12. doi: 10.1152/ajpregu.00268.2025. Online ahead of print.ABSTRACTMicroglia, the resident immune cells of the central nervous system (CNS), play a pivotal role in monitoring neuronal activity, maintaining tissue homeostasis, and orchestrating immune
Clin Transl Allergy. 2026 Jan;16(1):e70143. doi: 10.1002/clt2.70143.ABSTRACTBACKGROUND: Hereditary angioedema (HAE), defined by unpredictable, painful, acute swelling attacks affecting several bodily locations, diminishes patients' quality of life. Assessing disease activity, burden, and treatment r
J Vis Exp. 2025 Dec 23;(226). doi: 10.3791/69356.ABSTRACTPanvascular disease is a type of multi-systemic vascular disorder, primarily characterized by atherosclerotic vascular lesions as a common pathological feature, encompassing cardiovascular diseases, cerebrovascular diseases, and peripheral vas
Clin Appl Thromb Hemost. 2026 Jan-Dec;32:10760296251408357. doi: 10.1177/10760296251408357. Epub 2026 Jan 12.ABSTRACTObjectiveTo develop and validate a robust machine learning-based prediction model for assessing the risk of thrombotic events in critically ill cancer patients during their ICU stay.M
Clin Appl Thromb Hemost. 2026 Jan-Dec;32:10760296251410932. doi: 10.1177/10760296251410932. Epub 2026 Jan 12.ABSTRACTA globally prevalent cardiac arrhythmia, atrial fibrillation (AF) greatly increases the risk of thromboembolic events, making effective anticoagulation necessary. The mainstay of this
J Food Drug Anal. 2025 Dec 15;33(4):421-433. doi: 10.38212/2224-6614.3563.ABSTRACTThe highly selective SGLT2 inhibitor (SGLT2i) is reported to have beneficial effects on diabetic cardiac hypertrophy; however, the molecular mechanisms underlying the cardioprotection of SGLT2i are not fully understood
J Food Drug Anal. 2025 Dec 15;33(4):487-500. doi: 10.38212/2224-6614.3570.ABSTRACTArtificial intelligence (AI) technologies are increasingly integrated into healthcare, yet their economic value remains uncertain. Traditional economic evaluation methods may not adequately capture the unique features
Vasc Biol. 2026 Jan 12:VB-25-0011. doi: 10.1530/VB-25-0011. Online ahead of print.ABSTRACTAtherosclerosis is a progressive inflammatory disease which initiation and progression are potentially mediated by myeloid cells. An imbalance of oxygen supply and therefore hypoxic situations in the arterial w
Aging Dis. 2026 Jan 9. doi: 10.14336/AD.2025.0882. Online ahead of print.ABSTRACTAging is a major risk factor for a wide range of chronic diseases. Elucidating the molecular mechanisms underlying aging-associated disorders is essential for developing effective preventive and therapeutic strategies.
Aging Dis. 2026 Jan 5. doi: 10.14336/AD.2025.1258. Online ahead of print.ABSTRACTThe prevalence of aging-related diseases, including tumors, cardiovascular and cerebrovascular diseases, and fibrotic diseases, has been consistently increasing in the aging population. In these conditions, nucleolar st
Chem Biol Drug Des. 2026 Jan;107(1):e70238. doi: 10.1111/cbdd.70238.ABSTRACTThis study aimed to investigate the molecular mechanism by which tripartite motif-containing 24 (TRIM24) regulates the ubiquitination of sirtuin 1 (SIRT1) and to explore the protective effect of paeoniflorin (PF) on pulmonar
Clin Ter. 2026 Jan-Feb;177(1):114-122. doi: 10.7417/CT.2026.1982.ABSTRACTBACKGROUND: The efficacy and safety of endovascular treatment (EVT) for acute ischemic stroke (AIS) due to large-vessel occlusion (LVO) in the posterior circulation remain controversial. This study aimed to provide further evid
Clin Ter. 2026 Jan-Feb;177(1):100-103. doi: 10.7417/CT.2026.1980.ABSTRACTBACKGROUND: Hypertension is a major risk factor for cardiovascular disease. Despite pharmacologic interventions, a substantial proportion of patients exhibit poor blood pressure (BP) control. High sodium intake is a modifiable
Clin Ter. 2026 Jan-Feb;177(1):93-99. doi: 10.7417/CT.2026.1979.ABSTRACTINTRODUCTION: Women are vulnerable to depression, with evidence of MAO-A and HTTP gene variations' impact. We studied depression in women at a UAE hospital to analyze hormonal changes, psychological symptoms severity, and gene va
