The Impact of Inflammatory Hyperreflective Spots and Hard Exudates on Retinal Function in Diabetic Retinal Disease

Transl Vis Sci Technol. 2026 Jul 1;15(7):34. doi: 10.1167/tvst.15.7.34.ABSTRACTPURPOSE: To characterize the topography of hyperreflective spots (HRSs) and hard exudates (HEs) and to analyze their association with localized retinal sensitivity in diabetic retinal disease (DRD).METHODS: In this prospe

K Katharina Wall

Dapagliflozin and Acute Kidney Injury Following Cardiac Surgery: A Randomized Clinical Trial

JAMA. 2026 Jul 30. doi: 10.1001/jama.2026.9268. Online ahead of print.ABSTRACTIMPORTANCE: Two percent to 50% of patients undergoing elective cardiac surgery experience acute kidney injury (AKI) postoperatively. Medications to prevent AKI after elective cardiac surgery have not been identified.OBJECT

M Maartina J P Oosterom-Eijmael

Bilateral superselective adrenal artery embolization for primary aldosteronism: A comparative evaluation of clinical efficacy and safety

J Int Med Res. 2026 Jul;54(7):3000605261471347. doi: 10.1177/03000605261471347. Epub 2026 Jul 30.ABSTRACTObjectiveSuperselective adrenal arterial embolization with ethanol has demonstrated promising efficacy in patients with primary aldosteronism and lateralized aldosterone secretion. However, appro

D Dongliang Cao

A novel nutritional index for hypertension risk and prediction: Cross-sectional, prospective, and trajectory evidence from the English Longitudinal Study of Ageing

J Int Med Res. 2026 Jul;54(7):3000605261470980. doi: 10.1177/03000605261470980. Epub 2026 Jul 30.ABSTRACTObjectiveHypertension is a common and modifiable cardiovascular risk factor. The triglyceride-total cholesterol-body weight index is a novel metabolic indicator derived from routine clinical meas

F Fulong Luo

Failing Fontan following total cavopulmonary connection: extracardiac biomarkers reveal two distinct phenotypes with divergent clinical courses

Interdiscip Cardiovasc Thorac Surg. 2026 Jul 30:ivag213. doi: 10.1093/icvts/ivag213. Online ahead of print.ABSTRACTOBJECTIVES: Failing Fontan is an increasingly recognised complication after total cavopulmonary connection, yet longitudinal biomarker data remain scarce. We aimed to characterise the i

M Muneaki Matsubara

Contemporary outcomes of a DCB-based strategy with selective stent implantation for femoropopliteal artery lesions: results from the REAL-LEAD registry

CVIR Endovasc. 2026 Jul 30;9(1):93. doi: 10.1186/s42155-026-00744-1.ABSTRACTBACKGROUND: A drug-coated balloon (DCB)-based "leave-nothing-behind" strategy has become a predominant approach for femoropopliteal artery (FPA) lesions in contemporary clinical practice. However, despite the intention to co

T Takafumi Fujita

Benchmarking 54 large language model configurations for CAD-RADS scoring: open-weight models approach human-level agreement

Int J Cardiovasc Imaging. 2026 Jul 30. doi: 10.1007/s10554-026-03785-8. Online ahead of print.ABSTRACTThe Coronary Artery Disease Reporting and Data System (CAD-RADS) standardizes coronary CT angiography (CCTA) reporting, but not all reports contain CAD-RADS classifications. We benchmarked 54 large

V Veit Sandfort

Heart Failure with Preserved Ejection Fraction in Women: Sex-Specific Insights Across the Continuum from Diagnosis to Outcomes

Curr Cardiol Rep. 2026 Jul 30;28(1):73. doi: 10.1007/s11886-026-02392-2.ABSTRACTPURPOSE OF REVIEW: This review highlights differences in pathophysiologic mechanisms, diagnostic challenges and therapeutic responses of heart failure with preserved ejection fraction (HFpEF) in women.RECENT FINDINGS: Em

S Sharon Andrade-Bucknor

Low levels of low-density lipoprotein cholesterol in older adults are inversely associated with the incidence of coronary artery disease and all-cause mortality: the Shizuoka Kokuho Database study

Eur Geriatr Med. 2026 Jul 30. doi: 10.1007/s41999-026-01552-5. Online ahead of print.ABSTRACTPURPOSE: The risk of ischemic heart disease mortality increases linearly with increasing levels of low-density lipoprotein cholesterol (LDL-C). However, low LDL-C has been suggested as associated with mortal

S Sayaka Nagao-Sato

Ventricular Assist Device Use in Single Ventricle Heart Disease: Current Outcomes and Considerations

Curr Cardiol Rep. 2026 Jul 30;28(1):74. doi: 10.1007/s11886-026-02396-y.ABSTRACTPURPOSE OF REVIEW: Heart failure in patients with congenital heart disease and particularly single ventricle physiology at all stages of palliation presents significant management challenges. Ventricular assist device (V

T T Miller Sisson

Association between fish-related metabolites and metabolic syndrome risk factors in Japan: INTERLIPID metabolome -wide association study

Eur J Nutr. 2026 Jul 30;65(5):223. doi: 10.1007/s00394-026-04068-7.ABSTRACTBACKGROUND: Previous findings for the association of fish intake and its related metabolites on risk of metabolic syndrome (MetS) are inconsistent and limited. The prevalence of fish and shellfish consumers are high in Japan

T Tserenlkham Byambajav

Application of glutamine metabolism-related gene signatures in the non-invasive diagnosis of coronary artery disease: integrating bulk and single-cell transcriptomics

J Bioenerg Biomembr. 2026 Jul 30;58(1):42. doi: 10.1007/s10863-026-10125-x.ABSTRACTCoronary artery disease (CAD) is a common cardiovascular disorder strongly associated with glutamine metabolism. This study seeks to identify novel glutamine metabolism-related gene markers in CAD. Based on GEO datase

Z Zhiyong Zhao

Effect of long-term use of very low-carbohydrate Ketogenic diet on the thyroid gland and adipose tissue of adult male albino rats (biochemical and histological study)

J Mol Histol. 2026 Jul 30;57(4):253. doi: 10.1007/s10735-026-10907-y.ABSTRACTKetogenic diet (KD) therapy is a high-fat, low-carbohydrate, low-protein diet with a macronutrient ratio of 89% fat, 10% protein, and 1% carbohydrates. This causes the body's primary energy source to shift to lipids. Improv

R Randa Ahmed Ibrahim

A review of animal models of vascular dementia

Mol Biol Rep. 2026 Jul 30;53(1):1307. doi: 10.1007/s11033-026-12401-w.ABSTRACTVascular dementia (VD) is characterized by the presence of cerebrovascular lesions, specifically hemorrhagic or ischemic lesions within the brain parenchyma, with ischemic lesions being more prevalent. The resultant progre

Y Yuanyu Song

Association between kidney stones and major adverse cardiovascular events: a population-based analysis

Urolithiasis. 2026 Jul 30;54(1):128. doi: 10.1007/s00240-026-02028-8.ABSTRACTKidney stones are an increasingly common condition, and evidence suggests a link between stone formation and cardiovascular risk. This study aimed to investigate the association between kidney stones and major adverse cardi

A Ashton Smelser

Estimating healthy life years without activity limitations using medical claims data in Japan

Int J Epidemiol. 2026 Jun 24;55(4):dyag126. doi: 10.1093/ije/dyag126.ABSTRACTBACKGROUND: Healthy life years are estimated from national population surveys that assess limitations in daily activities. However, the infrequent timing and limited sample sizes hinder the timely and detailed assessment of

M Masahiro Nishi

Automated Echocardiographic Assessment of Left Atrial Remodeling in Atrial Fibrillation Using Dynamic HeartModel and AutoStrain LA

Echocardiography. 2026 Aug;43(8):e70568. doi: 10.1111/echo.70568.ABSTRACTPURPOSE: To compare left atrial (LA) size, emptying function, and strain among non-atrial fibrillation (AF) controls, patients with paroxysmal AF (PAF), and patients with persistent AF (PeAF) using automated 3D Dynamic HeartMod

X Xiaoyi Gong

The Achilles' Heel of Conduction System Pacing: Achieving Durable Left Bundle Branch Capture

No abstractJACC Clin Electrophysiol. 2026 Jul 18:S2405-500X(26)00582-7. doi: 10.1016/j.jacep.2026.06.029. Online ahead of print.NO ABSTRACTPMID:42530501 | DOI:10.1016/j.jacep.2026.06.029

J Jan de Pooter

Target Versus Below-Target Dose ACE Inhibitors in U.S. Veterans with HFpEF: Differential Outcomes by CKD Status

Eur J Heart Fail. 2026 Jul 30:xuag237. doi: 10.1093/ejhf/xuag237. Online ahead of print.ABSTRACTAIMS: Target-dose angiotensin-converting enzyme inhibitors (ACEIs), compared with below-target doses, have been associated with lower risks of death and kidney failure (KF) in patients with heart failure

F Frederick Lu

Association between Cardiac MRI-derived Global Longitudinal Strain and Clinical Outcomes in Chronic Aortic Regurgitation

Radiol Cardiothorac Imaging. 2026 Aug;8(4):e250239. doi: 10.1148/ryct.250239.ABSTRACTPurpose To examine the prognostic value of cardiac MRI-assessed left ventricular (LV) global longitudinal strain (GLS) in patients with moderate to severe chronic aortic regurgitation (AR). Materials and Methods Thi

G Go Hashimoto

Increased Excitability of Renal Sensory Neurons by Vasopressin in Male and Female Sprague Dawley Rats

Am J Hypertens. 2026 Jul 30:hpag095. doi: 10.1093/ajh/hpag095. Online ahead of print.ABSTRACTBACKGROUND: Preclinical models of cardiovascular and kidney diseases, such as hypertension and polycystic kidney disease (PKD), are associated with increased vasopressin (AVP) and increased renal afferent ne

S Sebastien Hayoz

Effect of Medications for Type 2 Diabetes on Cardiovascular Events and Mortality: A Comprehensive Pairwise and Network Meta-Analysis

Diabetes Obes Metab. 2026 Jul 30. doi: 10.1111/dom.71128. Online ahead of print.ABSTRACTAIM: To assess the effect of all the approved classes of medications for type 2 diabetes on Major Adverse Cardiovascular events (MACE) and all-cause mortality.METHODS: We performed a pairwise and network meta-ana

G Giovanni Antonio Silverii

Methodological Choices Strongly Modulate the Sensitivity and Specificity of Lesion-Symptom Mapping Analyses

Hum Brain Mapp. 2026 Aug;47(11):e70619. doi: 10.1002/hbm.70619.ABSTRACTLesion-symptom mapping results can vary substantially as a function of specific analysis parameters, but the extent to which individual methodological choices interact to modulate the sensitivity and specificity of results is not

M Margaret Jane Moore

The Ferroptosis-Related Mechanisms of Pentoxifylline in Atrial Fibrillation Treatment

Front Biosci (Landmark Ed). 2026 Jul 17;31(7):51871. doi: 10.31083/FBL51871.ABSTRACTBACKGROUND: Ferroptosis has been increasingly implicated in the pathophysiology of atrial fibrillation (AF). Pentoxifylline (PTX), a methylxanthine derivative, has shown potential therapeutic benefits in cardiovascul

J Jia-Bin Zhou