J Hypertens. 2025 Dec 30. doi: 10.1097/HJH.0000000000004227. Online ahead of print.ABSTRACTOBJECTIVES: Vascular aging (VA) is a prognostically relevant aspect of biological aging. We investigated its prevalence and determinants in Austria.METHODS: The LEAD (Lung, Heart, Social, Body) study is an ong
J Hypertens. 2026 Jan 6. doi: 10.1097/HJH.0000000000004239. Online ahead of print.ABSTRACTAlthough Nogo-B has been studied in neural development and vascular biology, its integrative role across renal, vascular and inflammatory pathways in hypertension has not yet been systematically reviewed. Here,
Rev Med Liege. 2026 Jan;81(1):29-32.ABSTRACTDilated cardiomyopathy (DCM) is a common cause of heart failure and may progress to acute decompensation requiring intensive care management. Genetic forms, particularly those associated with truncating mutations in the titin (TTN) gene, account for a sign
Rev Med Liege. 2026 Jan;81(1):21-28.ABSTRACTIschemic heart disease, the main clinical expression of atherosclerotic cardiovascular disease, remains a leading global health challenge. While coronary angiography is the gold standard for anatomical assessment, it has limitations in determining the func
Afr J Reprod Health. 2026 Jan 14;30(1):37-43. doi: 10.29063/ajrh2026/v30i1.5.ABSTRACTInfertility affects 15% of couples worldwide, with male factors contributing to over half of the cases. Varicocele, present in 35% of men with primary infertility, impairs sperm quality. This study evaluates the eff
<b>Introduction:</b> Iatrogenic pseudoaneurysms are uncommon but increasingly encountered complications due to the rising number of percutaneous interventions. For minor lesions, conservative treatment, such as pressure or observation, is often effective. However, its effectiveness depends on many f
<b>Introduction:</b> Colonic diverticular disease (diverticulosis) is a currently worldwide increasing gastrointestinal disorder with a particularly high prevalence in Western countries. The operative treatment of acute diverticulitis could be executed through open or laparoscopic techniques. A non-
J Clin Res Pediatr Endocrinol. 2026 Jan 15. doi: 10.4274/jcrpe.galenos.2025.2025-12-12. Online ahead of print.ABSTRACTPatients diagnosed with craniopharyngioma often experience rapid and pronounced weight gain that can progress to severe hypothalamic obesity. This phenomenon is predominantly attribu
Circ Cardiovasc Interv. 2026 Jan 15:e015867. doi: 10.1161/CIRCINTERVENTIONS.125.015867. Online ahead of print.ABSTRACTBACKGROUND: The prognostic implications of bolus thermodilution-derived resting coronary blood flow in all-comer patients with chronic coronary syndrome are not known. We investigate
Arterioscler Thromb Vasc Biol. 2026 Jan 15. doi: 10.1161/ATVBAHA.125.323000. Online ahead of print.ABSTRACTBACKGROUND: Abnormal levels of VWF (von Willebrand Factor) are a risk factor for venous thromboembolism (VTE) and bleeding. Genome-wide association studies for VWF have identified novel candida
Circ Res. 2026 Jan 15. doi: 10.1161/CIRCRESAHA.125.327726. Online ahead of print.ABSTRACTBACKGROUND: Direct cardiac reprogramming offers a promising therapeutic strategy for heart regeneration by converting endogenous fibroblasts to functional induced cardiomyocytes (iCMs) that integrate into the my
CONCLUSION: In Chinese men with negative prostate MRIs, PV > 55.25 mL, PSAD < 0.100 ng/mL², or PSAD^(adj) < 7.24 ng/mL may elevate mpMRI's NPV from 92% to 100%, enabling safe avoidance of unnecessary biopsies. Prospective multicenter validation is required to confirm these findings.Prostate Cancer.
Front Endocrinol (Lausanne). 2026 Jan 12;16:1730403. doi: 10.3389/fendo.2025.1730403. eCollection 2025.ABSTRACTBACKGROUND: Previous studies have shown that serum total bile acid levels are associated with both the presence of Coronary Heart Disease and the severity of coronary artery lesions. Corona
Maedica (Bucur). 2025 Dec;20(4):736-745. doi: 10.26574/maedica.2025.20.4.736.ABSTRACTBACKGROUND: Metabolic syndrome represented a clustering of abdominal obesity, dysglycaemia, dyslipidaemia and elevated blood pressure that together conferred an increased risk of type 2 diabetes and cardiovascular d
Eur Heart J Open. 2025 Dec 16;6(1):oeaf160. doi: 10.1093/ehjopen/oeaf160. eCollection 2026 Jan.ABSTRACTAIMS: Little is known regarding strategies to improve influenza vaccination uptake among individuals with atrial fibrillation (AF). We assessed the effect of electronically delivered behavioural nu
Eur Heart J Open. 2025 Dec 3;6(1):oeaf161. doi: 10.1093/ehjopen/oeaf161. eCollection 2026 Jan.ABSTRACTIn vitro gene editing using isogenic pairs of human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) has demonstrated the feasibility of introducing or correcting specific pathogenic
Eur Heart J Open. 2025 Dec 11;6(1):oeaf171. doi: 10.1093/ehjopen/oeaf171. eCollection 2026 Jan.ABSTRACTAIMS: Catheter ablation (CA) of ventricular tachycardia (VT) in patients with structural heart disease is usually reserved for those with recurrent implantable cardioverter defibrillator (ICD) shoc
Eur Heart J Open. 2026 Jan 13;6(1):oeaf166. doi: 10.1093/ehjopen/oeaf166. eCollection 2026 Jan.ABSTRACTAIMS: Left ventricular (LV) thrombus carries a high risk of death and systemic embolism. While warfarin has been the standard treatment, evidence comparing direct oral anticoagulants (DOACs) with w
EClinicalMedicine. 2025 Dec 27;91:103722. doi: 10.1016/j.eclinm.2025.103722. eCollection 2026 Jan.ABSTRACTBACKGROUND: Effective weight reduction interventions may significantly reduce obesity-related atherosclerotic cardiovascular disease (ASCVD) risk. However, evidence on the association between op
Eur Heart J Imaging Methods Pract. 2025 Dec 24;4(1):qyaf163. doi: 10.1093/ehjimp/qyaf163. eCollection 2026 Jan.ABSTRACTBACKGROUND: Echocardiographic measurements of the left ventricle (LV) are fundamental in diagnosing and monitoring cardiac disease. Still, current understanding of how heart rate in
Eur Heart J Imaging Methods Pract. 2026 Jan 13;4(1):qyaf157. doi: 10.1093/ehjimp/qyaf157. eCollection 2026 Jan.ABSTRACTPositron emission tomography (PET) is the most advanced myocardial perfusion (MPI) technique for the non-invasive assessment of coronary artery disease and its many manifestations,
Case Rep Cardiol. 2026 Jan 13;2026:8832570. doi: 10.1155/cric/8832570. eCollection 2026.ABSTRACTInfective endocarditis is a rare phenomenon that may have devastating consequences. While uncommon, the spectrum of causative organisms can include Corynebacterium species. Corynebacterium diphtheriae end
Front Cardiovasc Med. 2025 Dec 15;12:1699236. doi: 10.3389/fcvm.2025.1699236. eCollection 2025.ABSTRACTBACKGROUND: This case report documents the application of the Varipulse™ catheter in linear ablation, offering a successful exploratory experience for the linear ablation of atrial fibrillation.CAS
Gq G protein-coupled receptor (Gq-GPCR) signaling in glial fibrillary acidic protein-expressing (GFAP^(+)) glia is essential for neuron-glia interaction in the Central Nervous System (CNS). However, the exploration of the roles of Gq-GPCR signaling in peripheral GFAP^(+) glia has just begun. Our rec
