Cologne (Germany): Institute for Quality and Efficiency in Health Care (IQWiG); 2026 Feb 22.ABSTRACTRESEARCH QUESTION: The aim of this report is toassess the benefit of diagnostics using cardiac magnetic resonance imaging as part of a diagnostic strategy, compared with a diagnostic strategy without
Hypertension. 2026 Feb 13. doi: 10.1161/HYPERTENSIONAHA.125.26187. Online ahead of print.ABSTRACTAtrial fibrillation represents the most prevalent cardiac arrhythmia and is associated with substantial morbidity, including an increased risk for stroke and heart failure. The pathophysiology of atrial
Circulation. 2026 Feb 13. doi: 10.1161/CIRCULATIONAHA.125.076426. Online ahead of print.ABSTRACTBACKGROUND: Tissue-specific regulatory T cells (Tregs) accumulate in the heart after myocardial infarction (MI) and play a vital role in limiting inflammation and promoting tissue repair. However, the dev
Stroke. 2026 Feb 13. doi: 10.1161/STROKEAHA.125.053151. Online ahead of print.ABSTRACTBACKGROUND: Cerebrovascular disease is prevalent in older adults and is associated with cognitive impairment. Although the association between brain infarcts and cognition has been widely investigated, the contribu
Hypertension. 2026 Feb 13. doi: 10.1161/HYPERTENSIONAHA.125.25816. Online ahead of print.ABSTRACTBACKGROUND: Endothelial dysfunction is recognized as a crucial initiating factor for hypertension and associated cardiovascular/renal injury. Although MYDGF (myeloid-derived growth factor) is mainly deri
Circ Res. 2026 Feb 13. doi: 10.1161/CIRCRESAHA.125.326815. Online ahead of print.ABSTRACTBACKGROUND: Atherosclerotic vascular diseases remain the leading cause of death despite the use of lipid-lowering drugs. The development of more efficacious therapies targeting endothelial inflammation and endot
HLA. 2026 Feb;107(2):e70589. doi: 10.1111/tan.70589.ABSTRACTGenome-wide association studies have linked major histocompatibility complex (MHC) region loci to immune-related diseases, but their role in multiple myeloma (MM) progression from monoclonal gammopathy of undetermined significance (MGUS) re
Front Clin Diabetes Healthc. 2026 Jan 28;7:1765794. doi: 10.3389/fcdhc.2026.1765794. eCollection 2026.ABSTRACTIncreasing circulating levels of trimethylamine N-oxide (TMAO), a metabolite originating from both dietary sources and microbial metabolism in the gut, have drawn significant attention for t
Front Immunol. 2026 Jan 28;17:1738675. doi: 10.3389/fimmu.2026.1738675. eCollection 2026.ABSTRACTKidney transplantation has traditionally focused on maximizing graft survival, with immunosuppressive therapy as the cornerstone of care. However, long-term patient health requires a broader perspective
Afr J Thorac Crit Care Med. 2025 Dec 19;31(4):e3539. doi: 10.7196/AJTCCM.2025.v31i4.3539. eCollection 2025.ABSTRACTBACKGROUND: In most healthy adults, respiratory syncytial virus (RSV) causes mild self-limiting respiratory infection. However, vulnerable populations may present differently or have mo
Res Pract Thromb Haemost. 2026 Jan 13;10(1):103354. doi: 10.1016/j.rpth.2026.103354. eCollection 2026 Jan.ABSTRACTBACKGROUND: Obesity predisposes individuals to metabolic dysfunction-associated steatotic liver disease (MASLD), the hepatic manifestation of metabolic syndrome. Studies in mice suggest
Front Endocrinol (Lausanne). 2026 Jan 28;17:1754543. doi: 10.3389/fendo.2026.1754543. eCollection 2026.ABSTRACTDiabetic cognitive impairment (DCI) is a frequent complication of diabetes that significantly reduces the quality of life of elderly patients and substantially increases the societal health
Front Endocrinol (Lausanne). 2026 Jan 28;17:1744953. doi: 10.3389/fendo.2026.1744953. eCollection 2026.ABSTRACTAIMS: Male hypogonadism is highly prevalent among patients undergoing dialysis and carries significant clinical implications, although is often overlooked. Testosterone deficiency in this p
Front Endocrinol (Lausanne). 2026 Jan 28;17:1690617. doi: 10.3389/fendo.2026.1690617. eCollection 2026.ABSTRACTBACKGROUND: Diabetic foot ulcer (DFU) is one of the serious complications of type 2 diabetes (T2DM). Malnutrition is associated with amputation in DFU patients. We aimed to use the CONUT sc
Front Endocrinol (Lausanne). 2026 Jan 28;17:1720189. doi: 10.3389/fendo.2026.1720189. eCollection 2026.ABSTRACTBACKGROUND: Remnant cholesterol (RC) has been recognized as a critical risk factor for vascular diseases. However, its association with cardiovascular disease (CVD) and overall mortality in
Front Endocrinol (Lausanne). 2026 Jan 28;17:1686082. doi: 10.3389/fendo.2026.1686082. eCollection 2026.ABSTRACTOBJECTIVE: Diabetes mellitus (DM) poses a major global public health challenge. Prediabetes, a critical stage in the progression of DM, represents a pivotal window for intervention and prev
Cancer Surviv Res Care. 2025;3(1):2593011. doi: 10.1080/28352610.2025.2593011. Epub 2025 Dec 2.ABSTRACTPURPOSE: Cardiovascular disease (CVD) represents a leading cause of late morbidity and mortality among survivors of childhood cancer. This study aimed to address barriers to longitudinal survivorsh
Front Cardiovasc Med. 2026 Jan 28;13:1583290. doi: 10.3389/fcvm.2026.1583290. eCollection 2026.ABSTRACTBACKGROUND: Given the changing epidemiological and burden trends of non-rheumatic degenerative mitral valve disease (DMVD), it is crucial to re-examine geographical differences and trends. Here, we
Acta Pharm Sin B. 2026 Feb;16(2):930-947. doi: 10.1016/j.apsb.2025.11.014. Epub 2025 Nov 13.ABSTRACTCold exposure activates brown adipose tissue (BAT), to alleviate metabolic disorders. However, the mechanisms underlying the regulation of mitochondrial lipid droplet contact (MLC) in BAT and their as
Curr Ther Res Clin Exp. 2025 Dec 17;104:100817. doi: 10.1016/j.curtheres.2025.100817. eCollection 2026 Jun.ABSTRACTBACKGROUND: The rising global challenges of obesity and chronic inflammation contribute to an increased prevalence of metabolic disorders and cardiovascular diseases.OBJECTIVE: The goal
Popul Med. 2021 Nov;3:32. doi: 10.18332/popmed/143749.ABSTRACTINTRODUCTION: Cardiovascular disease (CVD) is a critical public health issue, with tobacco smoking the leading preventable cause. Perceptions of CVD risk in specific populations may differ by tobacco use status, potentially necessitating
Ther Adv Hematol. 2026 Feb 10;17:20406207261417140. doi: 10.1177/20406207261417140. eCollection 2026.ABSTRACTBACKGROUND: Patients with β-thalassemia major remain at risk for endothelial dysfunction and cardiac injury due to iron overload, oxidative stress, and chronic inflammation, even with iron-ch
F1000Res. 2026 Jan 31;14:1341. doi: 10.12688/f1000research.171338.2. eCollection 2025.ABSTRACTBACKGROUND: Myocardial ischemia is a dynamic, complex process characterized by hyperkalemia, acidosis, and ATP depletion. While these three conditions alter cardiomyocyte electrophysiology, it is difficult
Cureus. 2026 Jan 12;18(1):e101383. doi: 10.7759/cureus.101383. eCollection 2026 Jan.ABSTRACTTroponin elevations occurring during supraventricular tachycardia (SVT) are often interpreted as "demand ischemia" rather than indicative of obstructive coronary artery disease (CAD). Nonetheless, differentia
