Pathological suppression of binocular vision in stroke

Optom Vis Sci. 2026 Apr;103(4):e70003. doi: 10.1002/ovs2.70003.ABSTRACTPURPOSE: Two prior studies suggested a relationship between spatial neglect and reduced diplopia reporting. In spatial neglect with visual extinction phenomenon, the double image on the neglected side may be extinguished from per

K Kevin E Houston

Acute-phase reactants as predictors of chronic kidney disease incidence in Africans: the population-based prospective RODAM cohort study

Int J Epidemiol. 2026 Apr 17;55(3):dyag057. doi: 10.1093/ije/dyag057.ABSTRACTBACKGROUND: Chronic kidney disease (CKD) and chronic inflammation are highly prevalent in African populations, yet their relationship remains understudied. We examined the association between acute-phase reactants (C-reacti

M Muhulo M Mungamba

Applications of Carbonic Anhydrase Inhibitors in Arthritis, Neuropathic Pain, Acute Mountain Sickness, and Cerebral Ischemia

Subcell Biochem. 2026;123:163-177. doi: 10.1007/978-3-032-23172-7_8.ABSTRACTCarbonic anhydrase inhibitors (CAIs) have long been used as diuretics, topically acting antiglaucoma agents, anticonvulsants, and for the treatment of altitude sickness. Lately, they have shown promising results as anti-obes

A Alessio Nocentini

Pharmacokinetic Drug-Drug Interaction of Leritrelvir in Healthy Chinese Volunteers: A Single-Arm, Open-Label, Dual-Cohort Study

Clin Drug Investig. 2026 May 1. doi: 10.1007/s40261-026-01556-w. Online ahead of print.ABSTRACTBACKGROUND AND OBJECTIVES: Preclinical studies have shown that leritrelvir, an anti-coronavirus disease 2019 (COVID-19) drug, is a substrate of CYP3A and P-gp. It also inhibits CYP3A, CYP2C19, and OATP1B3.

J Jiao Peng

Efficacy and Safety of Intravenous Thrombolysis with Tenecteplase in Patients with Wake-Up Branch Atheromatous Disease

Transl Stroke Res. 2026 May 1;17(3):51. doi: 10.1007/s12975-026-01443-8.ABSTRACTBranch atheromatous disease (BAD), a subtype of acute ischemic stroke (AIS), is associated with a high risk of early neurological deterioration (END) and poor prognosis. Wake-up stroke (WUS), comprising 20%-30% of AIS ca

L Lili Zhu

MRA-based aneurysm occlusion assessment in the early phase after flow diverter treatment: a multicenter retrospective study focusing on the impact of aneurysm diameter

Neurosurg Rev. 2026 May 1;49(1):387. doi: 10.1007/s10143-026-04315-9.ABSTRACTBACKGROUND: Although it is well-known that most aneurysms occlude within 1 year after flow diverter (FD) treatment, the time course to occlusion, especially in the early period, has not been adequately studied.METHODS: This

S Satoshi Koizumi

Response to Commentary by Fan and Zhang on: a prospective analysis to assess the multifactorial risk of childhood-onset hypertension: the ExAMIN youth SA study

No abstractHypertens Res. 2026 Apr 30. doi: 10.1038/s41440-026-02663-z. Online ahead of print.NO ABSTRACTPMID:42062579 | DOI:10.1038/s41440-026-02663-z

C Chanelle Volschenk

EHMT2 aggravates vascular remodeling via epigenetic inhibition of GADD45G

Exp Mol Med. 2026 May 1. doi: 10.1038/s12276-026-01702-6. Online ahead of print.ABSTRACTEuchromatic histone-lysine N-methyltransferase 2 (EHMT2) has been implicated in cardiovascular diseases, yet its role in vascular remodeling remains incompletely understood. Here we investigated the contribution

Z Zelan Wang

Measuring gross motor skills in African children using the PERF-FIT

Commun Med (Lond). 2026 Apr 30;6(1):258. doi: 10.1038/s43856-026-01592-9.ABSTRACTBACKGROUND: Africa is facing a rising prevalence of non-communicable diseases (NCDs), driven by shifts in lifestyle and dietary habits. Children with delays in motor coordination are less likely to participate in physic

B Bouwien Smits-Engelsman

Comparative evaluation of nine insulin resistance indices for 10-year coronary artery disease risk prediction in non-diabetic adults

Sci Rep. 2026 Apr 30. doi: 10.1038/s41598-026-51393-2. Online ahead of print.ABSTRACTSurrogate indices of insulin resistance (IR) have been widely used to estimate cardiometabolic risk, yet comparative evidence among multiple indices in non-diabetic individuals remains limited. We aimed to evaluate

A Ali Tajik

Dose-dependent effects and mechanisms of exercise-like stimulation on cardiac injury and contractile function: outcomes of the MICRO-ATHLETE study

Basic Res Cardiol. 2026 Apr 30. doi: 10.1007/s00395-026-01182-9. Online ahead of print.ABSTRACTObservational studies revealed that exercise produces cardiac troponin release and cardiac fatigue in athletes. However, human in vivo studies offer limited insights into the underlying mechanisms of these

T Tom T J Luiken

Association of childhood-to-adulthood body size trajectories with cardiovascular risk and all cause mortality

Int J Obes (Lond). 2026 Apr 30. doi: 10.1038/s41366-026-02091-6. Online ahead of print.ABSTRACTBACKGROUND: The relationship between body size across the life course and risks of cardiovascular disease (CVD) and mortality remains incompletely understood, particularly regarding transitions from childh

F Feifei Tang

Impact of high-density lipoprotein cholesterol on cardiovascular diseases and all-cause mortality: a large-scale cohort study in Korea

Sci Rep. 2026 Apr 30. doi: 10.1038/s41598-026-50885-5. Online ahead of print.ABSTRACTThis study aimed to investigate the association of high-density lipoprotein cholesterol (HDL-C) levels with cardiovascular diseases (CVDs) and all-cause mortality and to determine differences based on the presence o

Y Youn Huh

Estimated health and economic effects of different salt reduction strategies on cardiovascular disease in Brazil: a microsimulation analysis

Sci Rep. 2026 Apr 30. doi: 10.1038/s41598-026-49991-1. Online ahead of print.ABSTRACTExcessive salt consumption is an important risk factor for cardiovascular diseases (CVD), especially through increased blood pressure. In Brazil, the average salt intake is almost twice the international recommendat

E Eduardo Augusto Fernandes Nilson

Exosomes derived from galangin preconditioned mesenchymal stem cells attenuate oxidative stress induced senescence and promote geriatric wound healing

No abstractSci Rep. 2026 Apr 30. doi: 10.1038/s41598-026-50218-6. Online ahead of print.NO ABSTRACTPMID:42062410 | DOI:10.1038/s41598-026-50218-6

S Su-Ying Wen

Association between adverse childhood experiences and cardiovascular disease risk in cardiovascular kidney metabolic syndrome stages 0 to 3

Sci Rep. 2026 Apr 30. doi: 10.1038/s41598-026-50188-9. Online ahead of print.ABSTRACTAdverse childhood experiences (ACE) significantly escalate the risk of cardiovascular disease (CVD). However, their specific impact on individuals suffering from cardiovascular kidney metabolic (CKM) syndrome remain

M Mingze Sun

Impaired glucose tolerance and mild diabetes induce β-cell dysfunction in mice

Nat Commun. 2026 Apr 30. doi: 10.1038/s41467-026-71528-3. Online ahead of print.ABSTRACTSevere chronic hyperglycaemia ( > 15 mM) causes impaired glycolytic and mitochondrial metabolism in pancreatic β-cells, leading to dramatically reduced insulin secretion and content. However, patients with type 2

E Elizabeth Haythorne

Left Atrial Time-to-Peak From Time-Resolved MR Angiography as a Noninvasive Indicator of Left Atrial Pressure Before Catheter Ablation of Atrial Fibrillation

Korean J Radiol. 2026 May;27(5):419-427. doi: 10.3348/kjr.2025.1622.ABSTRACTOBJECTIVE: To evaluate the performance of the left atrial time-to-peak (TTP) derived from time-resolved magnetic resonance angiography (TR-MRA) as a noninvasive indicator of left atrial pressure (LAP) in patients with atrial

J Jaemin Shim

Ethnic disparities in mortality from acute coronary syndromes: a systematic review and meta-analysis

Open Heart. 2026 Apr 30;13(1):e004072. doi: 10.1136/openhrt-2026-004072.ABSTRACTOBJECTIVE: To quantify ethnic disparities in mortality after acute coronary syndrome (ACS) by comparing outcomes in Black, Asian and hite population groups.METHODS: We conducted a systematic review and meta-analysis of o

Y Yasmin Mayet

Yangxinshi Tablet protects against post-myocardial infarction heart failure with reduced ejection fraction by improving energy metabolism through inhibition of FOXO1/PDK4 signaling

Chin J Nat Med. 2026 May;24(5):574-591. doi: 10.1016/S1875-5364(26)61119-3.ABSTRACTHeart failure (HF) is a major contributor to global morbidity and mortality, with myocardial infarction (MI)-induced HF accounting for a substantial proportion of cases. Although Yangxinshi Tablet (YXS) is clinically

J Jingwen Guo

Can Spasticity Be Prevented? Insights from Preclinical and Clinical Evidence

Phys Med Rehabil Clin N Am. 2026 May;37(2):329-340. doi: 10.1016/j.pmr.2026.01.006. Epub 2026 Feb 16.ABSTRACTSpasticity is a common and disabling consequence of central nervous system injury that evolves progressively over time. Although traditionally viewed as an unavoidable sequela, emerging precl

R Radha Korupolu

Community Health Worker Feedback on an mHealth Intervention for Hypertension in Rural Guatemala: Mixed Methods Formative Study

JMIR Form Res. 2026 Apr 17;10:e75471. doi: 10.2196/75471.ABSTRACTBACKGROUND: Hypertension remains a leading global health challenge, particularly in low- and middle-income countries (LMICs), where limited health care infrastructure and resources restrict effective management. Community health worker

A Alvaro Bermudez-Cañete

Multimodal Intelligent Monitoring of Parkinson Disease: Scoping Review of Progress and Translational Challenges

J Med Internet Res. 2026 Apr 17;28:e89057. doi: 10.2196/89057.ABSTRACTBACKGROUND: Parkinson disease (PD) is a progressive neurodegenerative disorder with a rapidly growing global prevalence. Current clinical assessments, such as the Unified Parkinson Disease Rating Scale, are limited by subjectivity

J Jianhui Tan

Clinical characteristics and five-year outcomes in a prospective Russian real-world heart failure cohort

Vascul Pharmacol. 2026 Apr 28:107612. doi: 10.1016/j.vph.2026.107612. Online ahead of print.ABSTRACTBACKGROUND: Despite advances in therapy, data on long-term survival and temporal mortality patterns in real-world heart failure (HF) populations, particularly during the critical early period after di

N Nana Pogosova