Acta Cardiol. 2025 Nov 27:1-15. doi: 10.1080/00015385.2025.2589958. Online ahead of print.ABSTRACTBACKGROUND: This study aimed to evaluate the predictive value of the triglyceride-glucose (TyG) index in combination with inflammatory markers-systemic immune-inflammation index (SII), neutrophil-to-lym
Eur Heart J. 2025 Nov 27:ehaf963. doi: 10.1093/eurheartj/ehaf963. Online ahead of print.ABSTRACTBACKGROUND AND AIMS: Diabetes is associated with increased risk of cardiovascular and renal disease. This study investigated the role of peptidylarginine deiminase 4 (PAD4), neutrophil extracellular traps
Drugs Real World Outcomes. 2025 Nov 27. doi: 10.1007/s40801-025-00526-6. Online ahead of print.ABSTRACTBACKGROUND: Hyperuricemia is a common comorbidity in patients with cardiovascular diseases and chronic kidney disease, often requiring long-term urate-lowering therapy. Febuxostat, a xanthine oxida
Curr Cardiol Rep. 2025 Nov 27;27(1):161. doi: 10.1007/s11886-025-02325-5.ABSTRACTPURPOSE OF THE REVIEW: Epicardial adipose tissue (EAT), the visceral fat of the heart, is highly inflammatory fat depot with pro-inflammatory transcriptome and proteosome. EAT contributes to the development and progress
Mol Biomed. 2025 Nov 27;6(1):124. doi: 10.1186/s43556-025-00365-5.ABSTRACTPhenotypic switching of vascular smooth muscle cells (VSMCs) from a contractile toward a synthetic phenotype plays a critical role in atherosclerosis. Although the redox-sensitive sentrin/Small Ubiquitin-like Modifier (SUMO)-s
Curr Cardiol Rep. 2025 Nov 27;27(1):158. doi: 10.1007/s11886-025-02314-8.ABSTRACTPURPOSE OF REVIEW: Accurate, timely quantification of cardiac function is central to the diagnosis, management, and monitoring of cardiovascular disease. This review synthesizes recent advances in artificial intelligenc
No abstractCell Biochem Biophys. 2025 Nov 27. doi: 10.1007/s12013-025-01952-7. Online ahead of print.NO ABSTRACTPMID:41307805 | DOI:10.1007/s12013-025-01952-7
Curr Cardiol Rep. 2025 Nov 27;27(1):159. doi: 10.1007/s11886-025-02320-w.ABSTRACTPURPOSE OF REVIEW: To provide clinicians with a concise introduction of microplastics potential role as a cardiovascular risk factor.RECENT FINDINGS: Microplastics have been identified in human cardiovascular tissues. I
Neurochem Res. 2025 Nov 27;51(1):4. doi: 10.1007/s11064-025-04615-4.ABSTRACTRepetitive transcranial magnetism (rTMS) exerts neuroprotective function in the cerebral ischemia/reperfusion (I/R) injury during the early stage. Intermittent theta-burst stimulation (iTBS), a more time-efficient modality o
Curr Cardiol Rep. 2025 Nov 27;27(1):166. doi: 10.1007/s11886-025-02302-y.ABSTRACTPURPOSE OF REVIEW: To summarize the key features of vulnerable plaques identified by intracoronary and non-invasive imaging and explore how anti-atherosclerotic therapies contribute to plaque regression and stabilizatio
Curr Cardiol Rep. 2025 Nov 27;27(1):163. doi: 10.1007/s11886-025-02323-7.ABSTRACTPURPOSE OF REVIEW: This review examines the growing role of extended reality (XR) (including virtual, augmented, and mixed reality) in the care of patients with congenital heart disease (CHD), with a focus on its use in
Curr Cardiol Rep. 2025 Nov 27;27(1):157. doi: 10.1007/s11886-025-02319-3.ABSTRACTPURPOSE OF REVIEW: This paper examines how digital health technologies can either reduce or exacerbate disparities in cardiovascular disease outcomes. It explores the role of the digital divide defined as a multifactori
Curr Cardiol Rep. 2025 Nov 27;27(1):162. doi: 10.1007/s11886-025-02324-6.ABSTRACTPURPOSE OF REVIEW: To summarize the recent literature examining the degree of overlap among atrial fibrillation (AF), heart failure (HF), and left atrial (LA) dysfunction, the prognostic relevance of finding a second co
Heart Fail Rev. 2025 Nov 27;31(1):2. doi: 10.1007/s10741-025-10582-3.ABSTRACTLeft ventricular assist device (LVAD) implantation is an important surgical option for patients with advanced heart failure (HF) who are not eligible for heart transplantation (destination therapy) or who are not expected t
Eur J Pediatr. 2025 Nov 27;184(12):799. doi: 10.1007/s00431-025-06596-6.ABSTRACTPURPOSE: The second year of life is gaining increased attention in the era of long-acting RSV immunoprophylaxis. This multicenter study, across pre- and post-COVID seasons, aimed to assess the association between specifi
Cell Biol Toxicol. 2025 Nov 27;41(1):159. doi: 10.1007/s10565-025-10114-7.ABSTRACTKRP-203, a novel agonist of sphingosine-1-phosphate receptors (S1PRs), has shown promise in treating in immune-related diseases by blocking lymphocyte recruitment to inflamed tissues. Although S1PRs are abundantly expr
Naunyn Schmiedebergs Arch Pharmacol. 2025 Nov 27. doi: 10.1007/s00210-025-04843-z. Online ahead of print.ABSTRACTGlobally, coronary artery disease (CAD) continues to be a major cause of morbidity and death. The intricate relationship between thrombosis and atherosclerosis means that even though anti
Acta Diabetol. 2025 Nov 27. doi: 10.1007/s00592-025-02624-x. Online ahead of print.ABSTRACTBACKGROUND AND AIMS: Thanks to the efforts made in the last century many patients with Type 1 Diabetes (T1D) are reaching and surpassing the age of 75, however, data on their clinical characteristics, prevalen
Cell Mol Life Sci. 2025 Nov 27. doi: 10.1007/s00018-025-05990-5. Online ahead of print.ABSTRACTVascular calcification is a pathological process commonly associated with cardiovascular diseases, diabetes, and renal insufficiency, driven by inflammation, oxidative stress, and endoplasmic reticulum str
Transl Stroke Res. 2025 Nov 27;17(1):1. doi: 10.1007/s12975-025-01391-9.ABSTRACTLaboratory ratios such as the neutrophil-to-lymphocyte, platelet-to-lymphocyte, and stress hyperglycemia ratios have been widely studied as prognostic markers in stroke. Despite hundreds of reports and multiple meta-anal
Curr Cardiol Rep. 2025 Nov 27;27(1):160. doi: 10.1007/s11886-025-02286-9.ABSTRACTPURPOSE OF REVIEW: The diagnostic, therapeutic, and prognostic management of patients with suspected acute coronary syndrome (ACS) is a major challenge for clinicians in both emergency and outpatient settings. While cle
Curr Cardiol Rep. 2025 Nov 27;27(1):164. doi: 10.1007/s11886-025-02287-8.ABSTRACTPURPOSE OF REVIEW: This review aims to provide a comprehensive contemporary overview regarding the clinical perspectives, multi-modality imaging evaluation, treatments and outcomes of subaortic stenosis (SAS).RECENT FIN
Curr Cardiol Rep. 2025 Nov 27;27(1):165. doi: 10.1007/s11886-025-02311-x.ABSTRACTPURPOSE OF REVIEW: Mitral regurgitation is a common and heterogeneous valve disease, with its prevalence increasing due to aging populations. This review aims to provide a comprehensive overview of the roles of transtho
Curr Cardiol Rep. 2025 Nov 27;27(1):168. doi: 10.1007/s11886-025-02328-2.ABSTRACTPURPOSE OF THE REVIEW: To describe recent advances in knowledge of familial hypercholesterolemia (FH).RECENT FINDINGS: There has been a significant advance in understanding the natural history, risk stratification, and
