Cologne (Germany): Institute for Quality and Efficiency in Health Care (IQWiG); 2026 Feb 22.ABSTRACTRESEARCH QUESTION: The aim of this report is toassess the benefit of diagnostics using cardiac magnetic resonance imaging as part of a diagnostic strategy, compared with a diagnostic strategy without
Nurs Outlook. 2026 Feb 3;74(2):102689. doi: 10.1016/j.outlook.2026.102689. Online ahead of print.ABSTRACTBACKGROUND: Cardiovascular disease (CVD) remains the leading cause of mortality in the United States, with hypertension disproportionately affecting historically disadvantaged groups. Doctor of N
Int Immunopharmacol. 2026 Feb 3;173:116318. doi: 10.1016/j.intimp.2026.116318. Online ahead of print.ABSTRACTSepsis, a systemic inflammatory response syndrome caused by infection, can lead to life-threatening multi-organ dysfunction. Among its complications, sepsis-induced cardiomyopathy (SIC) repre
JMIR Res Protoc. 2026 Feb 4;15:e80394. doi: 10.2196/80394.ABSTRACTBACKGROUND: Although physical activity (PA) participation has known health benefits, many individuals with hypermobility spectrum disorders (HSD) and hypermobile Ehlers-Danlos syndrome (hEDS) have difficulties participating in PA. HSD
Neurology. 2026 Mar 10;106(5):e214649. doi: 10.1212/WNL.0000000000214649. Epub 2026 Feb 4.ABSTRACTBACKGROUND AND OBJECTIVES: Previous studies have indicated an increased risk of cerebrovascular and coronary events shortly after cancer diagnosis. However, whether cancer affects mortality outcomes aft
FASEB J. 2026 Feb 15;40(3):e71540. doi: 10.1096/fj.202503913R.ABSTRACTAlthough extensive clinical and basic research has been conducted on diabetic cardiomyopathy (DbCM), the therapeutic efficacy for this condition remains significantly limited. Ubiquitin-specific peptidase 20 (USP20), a deubiquitin
Compr Physiol. 2026 Feb;16(1):e70106. doi: 10.1002/cph4.70106.ABSTRACTAdipose tissue ATGL has emerged as an important player in cardiovascular disease. Myocardial infarction is accompanied by sympathetic stimulation and activation of white adipose tissue and peripheral lipolysis. We therefore invest
Curr Opin Lipidol. 2026 Feb 3. doi: 10.1097/MOL.0000000000001028. Online ahead of print.ABSTRACTPURPOSE OF REVIEW: The purpose of this report is to summarize evidence supporting the use of nonfasting lipid testing for cardiovascular risk assessment, the potential reasons nonfasting lipid testing pre
Adv Sci (Weinh). 2026 Feb 4:e03894. doi: 10.1002/advs.202503894. Online ahead of print.ABSTRACTPenile squamous cell carcinoma (PSCC) is a rare genitourinary malignancy, and factors of its tumor microenvironment (TME) could serve as prognostic indicators for tumor recurrence and metastasis. Here, we
Sci Transl Med. 2026 Feb 4;18(835):eadu6425. doi: 10.1126/scitranslmed.adu6425. Epub 2026 Feb 4.ABSTRACTEndothelial dysfunction plays a critical role in the initiation and progression of vascular remodeling and pulmonary arterial hypertension (PAH). Sine oculis homeobox 1 (SIX1) is a developmentally
Sci Adv. 2026 Feb 6;12(6):eaea2310. doi: 10.1126/sciadv.aea2310. Epub 2026 Feb 4.ABSTRACTSuper-resolution microscopy in combination with genetic labeling methods allows imaging of single proteins in cells. However, visualizing endogenous proteins on primary cells remains challenging due to the use o
Sci Adv. 2026 Feb 6;12(6):eadw0899. doi: 10.1126/sciadv.adw0899. Epub 2026 Feb 4.ABSTRACTGlucagon-like peptide-1 receptor agonists (GLP-1RAs) are effective therapies for type 2 diabetes (T2D) and obesity, yet patient responses are variable, with GLP1R gene variation potentially linked to therapeutic
PLoS One. 2026 Feb 4;21(2):e0341800. doi: 10.1371/journal.pone.0341800. eCollection 2026.ABSTRACTThe systems regulating blood pressure and calcium-magnesium (Ca2+-Mg2+) homeostasis are increasingly recognized to have clinically relevant interactions, where alterations in one can lead to significant
PLoS One. 2026 Feb 4;21(2):e0340985. doi: 10.1371/journal.pone.0340985. eCollection 2026.ABSTRACTINTRODUCTION: Persistent atrial fibrillation (AFib) is the most common chronic arrhythmia in adults in the United States and is associated with significant morbidity, including thromboembolic events, str
JMIR Cardio. 2026 Feb 4;10:e79639. doi: 10.2196/79639.ABSTRACTBACKGROUND: Mindfulness-based interventions have been applied across various chronic illnesses, but no tailored program exists for individuals with pulmonary hypertension (PH).OBJECTIVE: This study aimed to develop and evaluate the feasib
PLoS One. 2026 Feb 4;21(2):e0338634. doi: 10.1371/journal.pone.0338634. eCollection 2026.ABSTRACTBACKGROUND: Guideline-Directed Medical Therapy (GDMT) is central to managing ischemic heart disease (IHD), yet its implementation remains suboptimal in low- and middle-income countries (LMICs), including
Arq Bras Oftalmol. 2026 Feb 2;89(1):e20250025. doi: 10.5935/0004-2749.2025-0025. eCollection 2026.ABSTRACTPURPOSE: Diabetic retinopathy screening in lowand middle-income countries is limited by restricted access to specialized care. Portable retinal cameras offer a practical alternative; however, im
Arq Bras Cardiol. 2025 Dec;122(12):e20250534. doi: 10.36660/abc.20250534.ABSTRACTBACKGROUND: Initial clinical and imaging associations in Takayasu's arteritis (TAK) are poorly defined.OBJECTIVES: To characterize initial manifestations, their associations, and long-term outcomes in a TAK cohort.METHO
Arq Bras Cardiol. 2025 Dec;122(12):e20250340. doi: 10.36660/abc.20250340.ABSTRACTBACKGROUND: Comprehensive physiological characterization of coronary endotypes remains limited, especially in epicardial dysfunction.OBJECTIVES: To describe hemodynamic profiles across the full spectrum of coronary endo
Arq Bras Cardiol. 2025 Dec;122(12):e20250331. doi: 10.36660/abc.20250331.ABSTRACTBACKGROUND: Evidence on the safety and anti-ischemic effects of exercise-based cardiac rehabilitation (ECR) in patients with refractory angina (RA) remains limited.OBJECTIVE: To evaluate the safety and efficacy of a 12-
Arq Bras Cardiol. 2025 Dec;122(12):e20250204. doi: 10.36660/abc.20250204.ABSTRACTBACKGROUND: Cardiovascular disease is the leading cause of mortality worldwide. Strategies that prioritize early diagnosis can reduce the incidence of related complications and cost.OBJECTIVE: To assess the cost-effecti
Arq Bras Cardiol. 2025 Dec;122(12):e20250188. doi: 10.36660/abc.20250188.ABSTRACTBACKGROUND: Advanced heart failure (HF) is associated with high morbidity and mortality rates, compromising the functionality and quality of life of patients and their families. Hospitalizations exacerbate disease sever
Arq Bras Cardiol. 2025 Dec;122(12):e20250112. doi: 10.36660/abc.20250112.ABSTRACTThrough the comparison of responses of normal volunteers, assessment of autonomic function under abnormal clinical conditions focused on the detection of dysautonomia involving both the parasympathetic and adrenergic li
Arq Bras Cardiol. 2025 Dec;122(12):e20250088. doi: 10.36660/abc.20250088.ABSTRACTBACKGROUND: Pulmonary valve regurgitation (PR) is often encountered in cardiac conditions, including heart failure (HF). Although typically tolerated, severe PR can lead to right ventricular dysfunction and negative cli
