J Cardiovasc Nurs. 2026 Sep 9. doi: 10.1097/JCN.0000000000001348. Online ahead of print.ABSTRACTBACKGROUND: Chronic heart disease is highly prevalent among adults over 65; however, the adoption and sustained use of mobile health applications to support self-management is limited. Understanding the m
J Cardiovasc Nurs. 2026 Sep 9. doi: 10.1097/JCN.0000000000001386. Online ahead of print.ABSTRACTBACKGROUND: Coronary heart disease (CHD) is a leading cause of death worldwide. While percutaneous coronary intervention (PCI) improves myocardial perfusion, it does not stop disease progression, making p
Am J Psychiatry. 2026 Sep 9:appiajp20250793. doi: 10.1176/appi.ajp.20250793. Online ahead of print.ABSTRACTOBJECTIVE: Long-acting injectable antipsychotics (LAIAs) can improve adherence, but their optimal use in bipolar disorder needs to be further explored. This study compared LAIAs and oral antips
Sci Prog. 2026 Jul-Sep;109(3):368504261484901. doi: 10.1177/00368504261484901. Epub 2026 Sep 8.ABSTRACTObjectiveTo investigate the association between the hemoglobin-to-red cell distribution width ratio (HRR) and in-hospital and 30-day mortality among critically ill patients with atrial fibrillation
Dig Dis Sci. 2026 Sep 8. doi: 10.1007/s10620-026-10236-w. Online ahead of print.ABSTRACTBACKGROUND: Whether established statin therapy should be continued after hospitalization for hepatic decompensation in metabolic dysfunction-associated steatotic liver disease (MASLD) cirrhosis remains uncertain.
J Neurol. 2026 Sep 8;273(10):581. doi: 10.1007/s00415-026-14103-6.ABSTRACTBACKGROUND: G protein-coupled receptor (GPCR) directed regulatory autoantibodies (RABs) have previously been linked to poor functional outcome after ischemic stroke. We investigated the impact of anti-α1/α2/β1/β2 receptor, end
Pediatr Res. 2026 Sep 8. doi: 10.1038/s41390-026-05479-2. Online ahead of print.ABSTRACTBACKGROUND: Body mass index (BMI) is widely used to assess pediatric obesity but does not fully capture adiposity-related organ dysfunction. The Clinical Framework of Obesity 2025 (CFO-2025), proposed by The Lanc
EMBO Mol Med. 2026 Sep 8. doi: 10.1038/s44321-026-00497-3. Online ahead of print.ABSTRACTGenome sequencing is the first-line diagnostic method for primary mitochondrial diseases (PMDs), yet its effectiveness is limited by variants of uncertain significance or unresolved genetic findings. We systemat
J Gen Intern Med. 2026 Sep 8. doi: 10.1007/s11606-026-10791-y. Online ahead of print.ABSTRACTDiabetes and heart failure are strongly correlated, and people with diabetes are more likely to rapidly transition to overt heart failure and develop symptoms. Early identification and management of heart fa
J Gen Intern Med. 2026 Sep 8. doi: 10.1007/s11606-026-10688-w. Online ahead of print.ABSTRACTBACKGROUND: The fellowship application process represents a critical step in the pathway to a subspecialty career for internal medicine residents. Understanding applicant factors associated with successful e
J Neurol. 2026 Sep 9;273(10):582. doi: 10.1007/s00415-026-14063-x.ABSTRACTBACKGROUND: Aneurysmal subarachnoid hemorrhage (aSAH) causes substantial morbidity and mortality, and guidelines recommend aneurysm repair as early as feasible. However, the association between onset-to-treatment time and outc
J Neurol. 2026 Sep 8;273(10):580. doi: 10.1007/s00415-026-14097-1.ABSTRACTOBJECTIVES: Transient Ischemic Attack (TIA) may induce subtle tissue damage that remains undetectable on conventional magnetic resonance imaging (MRI), which has led to growing interest in blood biomarkers of neuronal and glia
J Cardiovasc Transl Res. 2026 Sep 8;19(1):113. doi: 10.1007/s12265-026-10843-y.ABSTRACTCollagen prolyl 4-hydroxylase (C-P4H) is a key enzyme that controls collagen maturation and fibrotic matrix buildup. Cardiac fibrosis is a major pathological basis of many cardiovascular diseases. It is marked by
Sci Rep. 2026 Sep 8;16(1):28102. doi: 10.1038/s41598-026-70293-z.ABSTRACTOur study presents and applies a metabolomics-driven multi-omics integration strategy to elucidate dynamic pathway interactions during disease progression. We analyzed longitudinal metabolomics datasets from a Duchenne muscular
Eur J Pediatr. 2026 Sep 8;185(10):729. doi: 10.1007/s00431-026-07390-8.ABSTRACTKawasaki disease shock syndrome (KDSS) is a severe phenotype of Kawasaki disease (KD) characterized by hemodynamic instability and systemic inflammation. Early identification of children at risk for KDSS remains challengi
Exp Mol Med. 2026 Sep 9. doi: 10.1038/s12276-026-01835-8. Online ahead of print.ABSTRACTDespite significant biomedical advances, cardiovascular disease remains a leading cause of global mortality. The traditional 'bench-to-bedside' research pipeline, which heavily relies on animal models to guide cl
No abstractNat Rev Cardiol. 2026 Sep 8. doi: 10.1038/s41569-026-01349-w. Online ahead of print.NO ABSTRACTPMID:42711382 | DOI:10.1038/s41569-026-01349-w
Sci Rep. 2026 Jul 27;16(1):28069. doi: 10.1038/s41598-026-62796-6.ABSTRACTThe platelet to highdensity lipoprotein cholesterol ratio (PHR) is an emerging indicator reflecting the balance between thrombogenesis and lipid metabolism inflammation. This study aimed to investigate the relationship between
Nat Commun. 2026 Aug 11;17(1):9615. doi: 10.1038/s41467-026-76695-x.ABSTRACTThe auditory-cardiac interplay enables sound perception to modulate cardiac rhythm and homeostasis. However, its underlying regulatory mechanism and therapeutic potential remain largely underexplored, due to fundamental limi
Signal Transduct Target Ther. 2026 Sep 8;11(1):379. doi: 10.1038/s41392-026-03001-y.ABSTRACTCell death is essential for maintaining internal stability and metabolic balance in the human body and plays a key role in regulating physiological and pathological processes. Advances in understanding the li
Nat Commun. 2026 Aug 11;17(1):9611. doi: 10.1038/s41467-026-76595-0.ABSTRACTMultiple myeloma (MM) remains an incurable blood cancer. Obesity is a known risk factor, but how adipocytes promote MM progression is not fully understood. Here, we uncover a metabolic crosstalk between adipocytes and MM cel
JNCI Cancer Spectr. 2026 Sep 8:pkag089. doi: 10.1093/jncics/pkag089. Online ahead of print.ABSTRACTIMPORTANCE: Patients diagnosed with breast cancer (BCa) are at increased risk of multiple common diseases; however, the spectrum of these diseases and the contribution of inherited genetic susceptibili
Kidney Res Clin Pract. 2026 Sep 8. doi: 10.23876/j.krcp.26.091. Online ahead of print.ABSTRACTBACKGROUND: Diabetic kidney disease (DKD) is the leading cause of end-stage kidney disease (ESKD) worldwide. In South Korea, DKD accounts for nearly half of all ESKD cases, yet prospective data reflecting t
Farm Hosp. 2026 Sep 8:S1130-6343(26)00205-9. doi: 10.1016/j.farma.2026.08.005. Online ahead of print.ABSTRACTOBJECTIVE: To analyze the concordance between the stratification offered by the tool included in the adaptation of the capability-motivation-opportunity model for patients with cardiovascular
