Cardioprotection Is a Delivery Problem: A First-Medical-Contact Framework for Acute Myocardial Infarction

ACS Pharmacol Transl Sci. 2026 Sep 17;9(10):3000-3004. doi: 10.1021/acsptsci.6c00552. eCollection 2026 Oct 9.ABSTRACTDozens of agents that limit reperfusion injury preclinically have failed clinically. These failures are architectural, not biological: the right biology reaches the wrong place, as th

V Vibhudutta Awasthi

Mechanical circulatory support devices in heart failure: a narrative review of current evidence, clinical applications, complications, and future directions

Front Cardiovasc Med. 2026 Sep 29;13:1859170. doi: 10.3389/fcvm.2026.1859170. eCollection 2026.ABSTRACTMechanical circulatory support devices (MCSDs) have evolved from rescue therapy for refractory cardiogenic shock (CS) to an essential component of advanced heart failure management, spanning tempor

R Ruirui Zhu

Latent Class Analysis for Clustering Iranian Individuals Based on Cardiovascular Risk Factors

Med J Islam Repub Iran. 2026 Aug 17;40:88. doi: 10.47176/mjiri.40.88. eCollection 2026.ABSTRACTBACKGROUND: Cardiovascular disease (CVD) remains a major public health concern, and conventional risk-stratification tools, such as WHO/ISH (IraPEN), may not adequately capture the heterogeneity of risk pr

H Hajar Nikbakht

Hybrid approach with thoracic endovascular treatment and abdominal aortic replacement for acute type B aortic dissection complicated by ruptured abdominal aortic aneurysm

J Vasc Surg Cases Innov Tech. 2026 Sep 7;12(6):102504. doi: 10.1016/j.jvscit.2026.102504. eCollection 2026 Dec.ABSTRACTThe coexistence of a ruptured abdominal aortic aneurysm and acute aortic dissection is an unusual and life-threatening condition. We present the case of a patient who underwent simu

K Kaito Omine

Circadian mechanisms in heart failure: Cell-specific regulation and chrono-medicine

Cell Insight. 2026 Sep 5;5(6):100363. doi: 10.1016/j.cellin.2026.100363. eCollection 2026 Dec.ABSTRACTEmerging evidence indicates that circadian rhythms profoundly influence the pathophysiology of heart failure (HF). The circadian clock system governs myocardial functions via synchronized actions fr

S Shuting Cheng

Gut microbiota-derived tryptophan metabolites in cardiovascular disease: mechanisms, biomarkers, and precision interventions

Front Microbiol. 2026 Sep 29;17:1947695. doi: 10.3389/fmicb.2026.1947695. eCollection 2026.ABSTRACTThe gut microbiota plays a significant role in cardiovascular disease (CVD), through its metabolic products. Tryptophan is a key signaling molecule in the microbiota-host network; its gut microbial met

Q Qian Ding

Population burden of diabetes, hypertension, and cardiovascular disease attributable to obesity: a community-based study in Turkiye

Front Public Health. 2026 Sep 29;14:1963530. doi: 10.3389/fpubh.2026.1963530. eCollection 2026.ABSTRACTBACKGROUND: Obesity has emerged as a global public health pandemic, with rapidly increasing prevalence and a growing burden of obesity-related chronic diseases worldwide. Despite its high prevalenc

B Banu Ersoy Şen

Application and evidence gaps of sarcopenia diagnostic criteria in patients with heart failure: a scoping review

Front Med (Lausanne). 2026 Sep 29;13:1957639. doi: 10.3389/fmed.2026.1957639. eCollection 2026.ABSTRACTBACKGROUND: Diagnostic criteria for sarcopenia show heterogeneity in patients with heart failure (HF). This study reviews existing evidence through a scoping review.METHODS: We searched six databas

M Mingzhe Li

Impact of social determinants of health on perioperative and interstage outcomes in congenital heart surgery a systematic review

Front Cardiovasc Med. 2026 Sep 29;13:1881839. doi: 10.3389/fcvm.2026.1881839. eCollection 2026.ABSTRACTIMPORTANCE: Social determinants of health (SDoH)- conditions in which patients live, grow, and age,-are increasingly recognized to influence the health of patients with congenital heart disease (CH

S Sara Sakowitz

Vascular Phenotyping with Photoacoustic and Ultrasound Imaging in Cardiovascular Disease: Recent Innovations

Curr Treat Options Cardiovasc Med. 2026;28(1):29. doi: 10.1007/s11936-026-01162-1. Epub 2026 Oct 12.ABSTRACTPURPOSE OF REVIEW: Photoacoustic and ultrasound imaging together resolve vascular structure, wall biomechanics, blood flow, oxygenation, and tissue composition without ionizing radiation or io

M Muhang He

Simulation-guided outlet valve repair: early integration of computationally-derived principles of free-edge length in bicuspidization repair

Front Cardiovasc Med. 2026 Sep 29;13:1957668. doi: 10.3389/fcvm.2026.1957668. eCollection 2026.ABSTRACTBACKGROUND: Symmetric bicuspidization repair for outlet valve pathologies relies on the surgeon's subjective assessment. Recent computational and ex-vivo work suggests sizing free-edge length to 1.

P Perry Seo Choi

Efficacy and specific toxicity profiles of GPRC5D- versus BCMA-targeted bispecific antibodies in relapsed/refractory multiple myeloma: a meta-analysis of clinical trials and real-world studies

Front Immunol. 2026 Sep 29;17:1937154. doi: 10.3389/fimmu.2026.1937154. eCollection 2026.ABSTRACTBACKGROUND: Patients with relapsed/refractory multiple myeloma (RRMM) experience poor outcomes following multiple lines of therapy. Available evidence has largely pooled disparate immunotherapy platforms

J Jiahao Ji

Evidence, strategies, and pathways for thrombectomy in medium vessel occlusion stroke: a systematic review

Front Neurol. 2026 Sep 29;17:1838008. doi: 10.3389/fneur.2026.1838008. eCollection 2026.ABSTRACTBACKGROUND: Medium vessel occlusions (MeVOs) account for 25-40% of acute ischemic strokes and present a significant therapeutic frontier. Despite high technical success rates of endovascular thrombectomy

C Chenye Yang

Aortic coarctation and McArdle disease in histiocytosis-lymphadenopathy plus syndrome: expanding the SLC29A3 spectrum

JCEM Case Rep. 2026 Oct 13;4(11):luag289. doi: 10.1210/jcemcr/luag289. eCollection 2026 Nov.ABSTRACTHistiocytosis-lymphadenopathy plus syndrome (HLPS) is a rare inherited disorder caused by SLC29A3 variants. We report 2 Pakistani brothers with HLPS and markedly different clinical features despite id

B Bushra Rehman

Prevalence and factors associated with pulmonary hypertension in patients undergoing maintenance hemodialysis: a systematic review and meta-analysis

Front Med (Lausanne). 2026 Sep 28;13:1889032. doi: 10.3389/fmed.2026.1889032. eCollection 2026.ABSTRACTBACKGROUND: Maintenance hemodialysis (MHD) is a primary treatment for end-stage kidney disease (ESKD). Patients on long-term MHD frequently develop cardiovascular complications, with pulmonary hype

H Hong-Wei Yang

Association between insulin resistance-related indices and cardiovascular disease in patients with atopic dermatitis: mutual validation using real-world and NHANES data

Front Cardiovasc Med. 2026 Sep 29;13:1903179. doi: 10.3389/fcvm.2026.1903179. eCollection 2026.ABSTRACTBACKGROUND: The number of patients with atopic dermatitis (AD) who develop cardiovascular disease (CVD) has been increasing year by year. However, reliable biomarkers for identifying AD patients wi

Y Yu An

Excessive supraventricular ectopic activity and new-onset ischemic stroke: a retrospective cohort study with prospective outcome ascertainment

Front Neurol. 2026 Sep 29;17:1921826. doi: 10.3389/fneur.2026.1921826. eCollection 2026.ABSTRACTBACKGROUND: Excessive supraventricular ectopic activity (ESVEA), a marker of both paroxysmal atrial fibrillation (pAF) and underlying atrial cardiomyopathy, may serve as an earlier electrographic predicto

M Min Yang

Comparison of hybrid coronary revascularization and minimally invasive multivessel CABG for multivessel coronary artery disease

Front Cardiovasc Med. 2026 Sep 29;13:1887132. doi: 10.3389/fcvm.2026.1887132. eCollection 2026.ABSTRACTBACKGROUND: This study aimed to compare the perioperative and early-to-mid-term outcomes of hybrid coronary revascularization (HCR) and minimally invasive multivessel coronary artery bypass graftin

T Ting Ren

From wrist to heart: clinical validation and real-world translation of wearable and portable AI-enhanced electrocardiography

Eur Heart J Digit Health. 2026 Oct 1;7(8):ztag155. doi: 10.1093/ehjdh/ztag155. eCollection 2026 Oct.ABSTRACTWearable and portable electrocardiogram (ECG) devices are shifting cardiovascular monitoring beyond clinician-directed testing, driven by consumer-led self-monitoring, remote care, and prevent

A Ahmed El-Medany

Changes in birth certificate-reported prevalence of congenital anomalies at live birth during the COVID-19 pandemic: a nationwide study of 26 million United States live births

Front Cell Infect Microbiol. 2026 Sep 29;16:1914021. doi: 10.3389/fcimb.2026.1914021. eCollection 2026.ABSTRACTBACKGROUND: Although the majority of studies have indicated that maternal severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and coronavirus disease 2019 (COVID-19) vacc

Q Qinchang Chen

Serum free eicosapentaenoic acid-to-arachidonic acid ratio and long-term risk of major adverse cardiovascular events in patients with coronary artery disease

Front Cardiovasc Med. 2026 Sep 29;13:1944383. doi: 10.3389/fcvm.2026.1944383. eCollection 2026.ABSTRACTBACKGROUND: The eicosapentaenoic acid to arachidonic acid (EPA/AA) ratio reflects the balance between n-3 and n-6 polyunsaturated fatty acids. We examined the association between the serum free (no

C Changguo Ou

Comprehensive metabolomic characterization of patients with myasthenia gravis

Front Immunol. 2026 Sep 29;17:1906581. doi: 10.3389/fimmu.2026.1906581. eCollection 2026.ABSTRACTBACKGROUND: Myasthenia gravis (MG) is mediated by abnormal antibody generation and is characterized by muscle weakness and pathological fatigue. However, the accuracy of anti-acetylcholine receptor (AChR

H Hui Deng

The associations between dynapenic obesity and cognitive disorder in older hypertension patients: a multicenter cross-sectional study

Front Public Health. 2026 Sep 29;14:1893791. doi: 10.3389/fpubh.2026.1893791. eCollection 2026.ABSTRACTBACKGROUND: Evidence regarding the associations between dynapenic obesity and cognitive disorder in older adults is limited. This study aimed to investigate the prevalence of cognitive disorder amo

P Pingping An

Night-to-night sleep variability and all-cause and cardiovascular mortality: a prospective cohort study with a complementary in vitro circadian-disruption experiment

Front Med (Lausanne). 2026 Sep 29;13:1917205. doi: 10.3389/fmed.2026.1917205. eCollection 2026.ABSTRACTBACKGROUND: Irregular sleep-wake patterns may disrupt circadian rhythms, but the dose-response relationship between night-to-night sleep variability and mortality and the association of sleep onset

J Jing Bai