Virulence. 2025 Dec;16(1):2597565. doi: 10.1080/21505594.2025.2597565. Epub 2025 Dec 4.ABSTRACTSepsis-induced cardiomyopathy (SICM) is a severe complication of sepsis, especially in children, and identification of novel therapeutic targets remains essential for improving patient outcomes. Recent stu
Eur Heart J. 2025 Dec 4:ehaf980. doi: 10.1093/eurheartj/ehaf980. Online ahead of print.ABSTRACTBACKGROUND AND AIMS: Sepsis remains one of the leading causes of death worldwide, and sepsis-induced cardiomyopathy (SICM) increases the overall mortality rate of sepsis patients. Currently, targeting ther
Eur Heart J. 2025 Dec 4:ehaf1001. doi: 10.1093/eurheartj/ehaf1001. Online ahead of print.ABSTRACTCardiovascular disease (CVD) accounts for more deaths in women than breast cancer, lung cancer and chronic lung disease combined, with a comparable mortality to that of men. Many women and physicians do
JMIR Bioinform Biotechnol. 2025 Jul 31;6:e70621. doi: 10.2196/70621.ABSTRACTBACKGROUND: Prediabetes is an intermediate stage between normal glucose metabolism and diabetes and is associated with increased risk of complications like cardiovascular disease and kidney failure.OBJECTIVE: It is crucial t
Kidney Res Clin Pract. 2025 Nov 28. doi: 10.23876/j.krcp.25.112. Online ahead of print.ABSTRACTBACKGROUND: Protein-energy wasting (PEW) is a strong indicator of adverse outcomes such as all-cause death and cardiovascular events. Although this association has been established in dialysis patients, it
Kidney Res Clin Pract. 2025 Nov 26. doi: 10.23876/j.krcp.25.210. Online ahead of print.ABSTRACTExome sequencing (ES) and genome sequencing (GS) are essential for diagnosing rare genetic disorders, yet a significant number of patients remain without a definitive diagnosis after the initial analysis.
No abstractArterioscler Thromb Vasc Biol. 2025 Dec 4. doi: 10.1161/ATVBAHA.125.323926. Online ahead of print.NO ABSTRACTPMID:41342142 | DOI:10.1161/ATVBAHA.125.323926
CONCLUSIONS: PKA phosphorylation of Rad, which disinhibits Ca(v)1.3 channels and cAMP-dependent activation of HCN channels, are key effectors in β-adrenergic regulation of cardiac pacemaker activity and can sustain positive chronotropic effects independently. These findings on Rad-mediated regulatio
Circ Cardiovasc Imaging. 2025 Dec 4:e018862. doi: 10.1161/CIRCIMAGING.125.018862. Online ahead of print.ABSTRACTBACKGROUND: A formal prognostic staging system in wild-type transthyretin amyloid cardiomyopathy (ATTRwt-CM), based on echocardiographic imaging, is lacking. We evaluated the prognostic pe
Eur J Neurol. 2025 Dec;32(12):e70461. doi: 10.1111/ene.70461.ABSTRACTBACKGROUND AND AIMS: Previous randomized trials, such as CHANCE and POINT, have shown that dual antiplatelet therapy (DAPT) reduces ischemic event recurrence. However, its effectiveness depends on accurate dosage and timely adminis
Zhongguo Yi Liao Qi Xie Za Zhi. 2025 Sep 30;49(5):545-552. doi: 10.12455/j.issn.1671-7104.250178.ABSTRACTCardiovascular disease (CVD) is the leading cause of death worldwide. As the key pathological basis of CVD, arteriosclerosis holds great significance for early screening. However, existing clinic
Muscle Nerve. 2025 Dec 4. doi: 10.1002/mus.70088. Online ahead of print.ABSTRACTINTRODUCTION/AIMS: To study the association of risk factors with axonal degeneration, based on below-threshold sural nerve amplitudes, as a proxy for distal symmetric polyneuropathy (DSP). In particular, to assess the di
EuroIntervention. 2025 Dec 1;21(23):e1445-e1455. doi: 10.4244/EIJ-D-25-00566.ABSTRACTBACKGROUND: Abbreviated antiplatelet therapy (APT) can reduce bleeding without increasing ischaemic harm in high bleeding risk (HBR) patients undergoing percutaneous coronary intervention (PCI). The impact of chroni
EuroIntervention. 2025 Dec 1;21(23):e1424-e1433. doi: 10.4244/EIJ-D-25-00296.ABSTRACTCalcified nodules (CNs) represent significant challenges in percutaneous coronary intervention (PCI) due to their complex morphology, variable treatment responses, and association with stent failure due to reprotrus
EuroIntervention. 2025 Dec 1;21(23):e1399-e1423. doi: 10.4244/EIJ-D-25-00100.ABSTRACTNon-ST-segment elevation acute coronary syndrome (NSTE-ACS) represents a unique clinical syndrome, comprising non-ST-segment elevation myocardial infarction (NSTEMI) and unstable angina. NSTEMI, as the more common a
Eur Rev Med Pharmacol Sci. 2025 Nov;29(11):550-558. doi: 10.26355/eurrev_202511_37507.ABSTRACTOBJECTIVE: Deep vein thrombosis (DVT) poses a critical health risk, especially among the elderly. This study aims to enhance the specificity of DVT diagnosis by integrating novel inflammatory ratios and hem
JHLT Open. 2025 Nov 1;11:100421. doi: 10.1016/j.jhlto.2025.100421. eCollection 2026 Feb.ABSTRACTBACKGROUND: Many pediatric heart transplant (HT) recipients have decreased physical activity, which worsens their cardiovascular risk profile, contributes to long-term morbidity and mortality, and is asso
Front Bioinform. 2025 Nov 18;5:1716375. doi: 10.3389/fbinf.2025.1716375. eCollection 2025.ABSTRACTINTRODUCTION: Tumor necrosis factor-alpha (TNF-alpha) is a central mediator of chronic inflammation and a validated therapeutic target in atherosclerosis and related cardiovascular disorders. Peptide th
No abstractStruct Heart. 2025 Nov 20;9(12):100749. doi: 10.1016/j.shj.2025.100749. eCollection 2025 Dec.NO ABSTRACTPMID:41341981 | PMC:PMC12670123 | DOI:10.1016/j.shj.2025.100749
Rev Bras Ginecol Obstet. 2025 Nov 18;47:e-rbgo77. doi: 10.61622/rbgo/2025rbgo77. eCollection 2025.ABSTRACTOBJECTIVE: To evaluate adherence to preeclampsia prophylaxis with aspirin and calcium carbonate among pregnant women with chronic hypertension attending a specialized hypertension in pregnancy c
Rev Bras Ginecol Obstet. 2025 Nov 18;47:e-rbgo71. doi: 10.61622/rbgo/2025rbgo71. eCollection 2025.ABSTRACTOBJECTIVE: To test the hypothesis that the quarterly injectable contraceptive increases the activity of the renin-angiotensin-aldosterone system.METHODS: This was a cross-sectional observational
Rev Bras Ginecol Obstet. 2025 Oct 21;47:e-rbgo69. doi: 10.61622/rbgo/2025rbgo69. eCollection 2025.ABSTRACTOBJECTIVE: This study aimed to investigate the relationship between blood pressure (BP) responses during a mental stress test with 24-hour ambulatory BP (ABPM) and its variability (BPV) in postm
Prev Med Rep. 2025 Nov 15;60:103314. doi: 10.1016/j.pmedr.2025.103314. eCollection 2025 Dec.ABSTRACTOBJECTIVE: To evaluate the association between body roundness index (BRI) and 10-year atherosclerotic cardiovascular disease (ASCVD) risk and to compare its predictive performance with body mass index
African American women are disproportionately troubled with cardiometabolic complications of pregnancy (CMC(Preg)), including gestational diabetes, gestational hypertension, and preeclampsia. These adverse outcomes of pregnancy often lead to future diagnoses of diabetes mellitus, chronic hypertensio
