Phytother Res. 2026 Jan 11. doi: 10.1002/ptr.70203. Online ahead of print.ABSTRACTVascular aging, a central feature of organismal aging, involves endothelial cell (EC) structural and functional alterations. Methylglyoxal (MGO), a key advanced glycation end product precursor, pathologically accumulat
Phytother Res. 2026 Jan 11. doi: 10.1002/ptr.70145. Online ahead of print.ABSTRACTNeointima formation, characterized by similarities to tumor-like growth, plays a pivotal role in the progression of vascular occlusive diseases. Oroxylin A (OroA), a bioactive flavonoid from Scutellaria roots, shows pr
Immun Inflamm Dis. 2026 Jan;14(1):e70282. doi: 10.1002/iid3.70282.ABSTRACTBACKGROUND: Macrophages are a key component of innate immunity and regulate cardiac phenotypes by their polarization state. The classical M1 macrophages are activated by pro-inflammatory stimuli, whereas M2 macrophages are act
Alzheimers Dement. 2025 Dec;21 Suppl 2:e106886. doi: 10.1002/alz70856_106886.ABSTRACTBACKGROUND: Elevated plasma neurofilament light chain (NfL) is a promising biomarker for dementia diagnosis. However, it has also been reported to be associated with age, body mass index (BMI), and comorbidities suc
Orv Hetil. 2026 Jan 11;167(2):43-50. doi: 10.1556/650.2026.33457. Print 2026 Jan 11.ABSTRACTINTRODUCTION: Acute ischemic stroke is one of the leading causes of disability and mortality in adults, representing a major public health burden also in Hungary. Functional recovery is influenced by a wide r
Basic Res Cardiol. 2026 Jan 11. doi: 10.1007/s00395-025-01156-3. Online ahead of print.ABSTRACTImmune checkpoint inhibitors have significantly advanced cancer treatment, but they can lead to immune-related adverse events. Among these, immune checkpoint inhibitor-associated myocarditis (ICI-M) repres
Gut Microbes. 2026 Dec 31;18(1):2611617. doi: 10.1080/19490976.2025.2611617. Epub 2026 Jan 11.ABSTRACTGut microbiota research has rapidly expanded our understanding of host-microbe interactions in cardiovascular diseases, yet translation of these insights remains challenged by species-specific diffe
Alzheimers Dement. 2025 Dec;21 Suppl 2:e106766. doi: 10.1002/alz70856_106766.ABSTRACTBACKGROUND: White matter hyperintensities (WMHs) are a hallmark of cerebral small vessel disease (CSVD) linked to cognitive impairment and risk of dementia. Several risk factors are associated with WMH, but their co
Brief Bioinform. 2026 Jan 7;27(1):bbaf714. doi: 10.1093/bib/bbaf714.ABSTRACTCausal inference is an essential approach for understanding biological processes. Traditional causal inference methods assume a linear relationship between different biological traits, whereas their true causal relationship
Croat Med J. 2026 Jan 5;66(6):456-459.ABSTRACTCerebrofacial arteriovenous metameric syndrome (CAMS) is a rare nonhereditary disease, amounting to only 0.5% of all cerebral vascular malformations. It is characterized by vascular malformations in a metameric distribution involving the cerebrofacial re
Croat Med J. 2026 Jan 5;66(6):446-455.ABSTRACTAlthough the role of pharmacogenomics (PGx) in personalized pharmacotherapy has been well established, its implementation in clinical practice lags behind. In this article, we present an overview of important achievements in the field of PGx of cardiovas
Alzheimers Dement. 2025 Dec;21 Suppl 2:e105926. doi: 10.1002/alz70856_105926.ABSTRACTBACKGROUND: Neighborhood disadvantage, a key social determinant of health (SDOH), is associated with systemic inflammation and increased cardiometabolic risk, both of which contribute to Alzheimer's disease (AD) pat
HGG Adv. 2026 Jan 10:100566. doi: 10.1016/j.xhgg.2026.100566. Online ahead of print.ABSTRACTGene-environment interactions may enhance our understanding of blood pressure (BP) biology. We conducted a meta-analysis of multi-population genome-wide association studies of BP traits accounting for gene-de
Rheumatology (Oxford). 2026 Jan 10:keag017. doi: 10.1093/rheumatology/keag017. Online ahead of print.ABSTRACTOBJECTIVES: To evaluate for the first time a combination of novel colour Doppler ultrasound (CDUS), greyscale (GSUS), and oscillometric indices of angiopathy in patients with autoinflammatory
Am J Case Rep. 2026 Jan 11;27:e949903. doi: 10.12659/AJCR.949903.ABSTRACTBACKGROUND Endovascular aneurysm repair (EVAR) effectively treats abdominal aortic aneurysms but risks complications, including endoleak and graft infection. CASE REPORT A 74-year-old man with EVAR, complicated by endoleak the
J Gerontol B Psychol Sci Soc Sci. 2026 Jan 10:gbaf271. doi: 10.1093/geronb/gbaf271. Online ahead of print.ABSTRACTOBJECTIVES: Retirement marks a pivotal life stage for many individuals. As older adults transition into retirement, changes in lifestyle, income, and social networks can significantly in
Eur J Hum Genet. 2026 Jan 10. doi: 10.1038/s41431-025-02009-2. Online ahead of print.ABSTRACTThe expansion of genomics provides opportunity to screen individuals beyond clinical indication yet the classification of genomic variants and implications for health outcomes in this context is still emergi
Commun Biol. 2026 Jan 10. doi: 10.1038/s42003-026-09515-z. Online ahead of print.ABSTRACTThe development and maturation of B lymphocytes are critical for adaptive immunity, relying on tightly regulated gene programs within specialized microenvironments shaped by extracellular matrix and neighboring
Commun Med (Lond). 2026 Jan 10. doi: 10.1038/s43856-025-01363-y. Online ahead of print.ABSTRACTBACKGROUND: Systematic profiling of plasma proteins in population studies offers a complementary approach to discovery of novel risk factors and may provide new insights into the causes of coronary heart d
NPJ Digit Med. 2026 Jan 10. doi: 10.1038/s41746-025-02323-5. Online ahead of print.ABSTRACTWe address a critical clinical gap in real-world kidney transplantation (KT), the long-standing disconnect between structured longitudinal follow-up and text-defined clinical rules, which often leads to incons
Support Care Cancer. 2026 Jan 11;34(2):84. doi: 10.1007/s00520-025-10295-1.ABSTRACTPURPOSE: As people live longer after a cancer diagnosis, there is an increasing need to focus on chronic disease state management in the primary care setting. Particular attention to appropriate statin prescribing in
No abstractCardiooncology. 2026 Jan 10. doi: 10.1186/s40959-025-00432-4. Online ahead of print.NO ABSTRACTPMID:41519927 | DOI:10.1186/s40959-025-00432-4
BMC Public Health. 2026 Jan 10. doi: 10.1186/s12889-026-26189-8. Online ahead of print.ABSTRACTBACKGROUND: In China, leukemia remains one of the top ten causes of death, and understanding its mortality trends is crucial for public health planning. This study analyzed the mortality trends of leukemia
BMC Public Health. 2026 Jan 10. doi: 10.1186/s12889-025-26141-2. Online ahead of print.ABSTRACTExcessive consumption of carbonated soft drinks (CSDs) is associated with significant public health consequences, including increased risk of obesity, type 2 diabetes, cardiovascular diseases, hypertension
