Glucagon-Like Peptide-1 Receptor Agonists and Risk for Ischemic Optic Neuropathy : A Target Trial Emulation

Ann Intern Med. 2026 Jul 14. doi: 10.7326/ANNALS-25-00860. Online ahead of print.ABSTRACTBACKGROUND: There are few data evaluating the association between glucagon-like peptide-1 receptor agonists (GLP-1RAs) and nonarteritic anterior ischemic optic neuropathy (NAION), which constitutes approximately

K Kamika R Reynolds

Yorga Moorditj Koort: Aboriginal and Torres Strait Islander women's perspectives about heart health on Noongar Boodjar

Health Promot Int. 2026 Jul 1;41(4):daag088. doi: 10.1093/heapro/daag088.ABSTRACTIn Australia, despite overall declines in cardiovascular disease (CVD)-related mortality, Aboriginal and Torres Strait Islander women develop heart disease earlier and experience more than twice the rate of related morb

E Elia Bidgood

Design and Preliminary Testing of the CardioCare System in Health Checkup Centers: Implementation Report

JMIR Med Inform. 2026 Jul 13;14:e78942. doi: 10.2196/78942.ABSTRACTBACKGROUND: Health checkup programs in China reach millions of older adults for cardiovascular risk screening, but few effective mechanisms exist to ensure high-risk individuals receive follow-up preventive care.OBJECTIVE: We develop

Y Yan Wang

Low Statin Use Post-liver Transplant Despite Increased Rates of Dyslipidemia

J Pharm Pract. 2026 Jul 13:8971900261469304. doi: 10.1177/08971900261469304. Online ahead of print.ABSTRACTPrevious literature has demonstrated that hyperlipidemia is common post-transplant; however, low statin utilization has been seen post-liver transplant. Furthermore, assessment of statin qualif

S Sarah Blocker

Morquio Syndrome for Aortic Valve Replacement: Anesthesia Concerns - A Case Report

Ann Card Anaesth. 2026 Jul 1;29(3):417-420. doi: 10.4103/aca.aca_249_25. Epub 2026 Jul 13.ABSTRACTMorquio syndrome is a lysosomal storage disease that can lead to glycosaminoglycan deposition in the tissues. Skeletal deformities, cardiovascular complications, and airway abnormalities are well-recogn

J Jupi Talukdar

Ligand-Mediated Reprogramming Redirects Liver-Tropic Ionizable Lipid Nanoparticles for Lung-Selective mRNA Delivery

Angew Chem Int Ed Engl. 2026 Jul 13:e6080664. doi: 10.1002/anie.6080664. Online ahead of print.ABSTRACTSystemic delivery of messenger RNA (mRNA) to target tissues and cells using lipid nanoparticles (LNPs) holds transformative potential for gene therapy. However, most clinically validated LNP exhibi

Z Zhuxiao Gu

Transforming Pulmonary Arterial Hypertension: Key Milestones and Future Perspectives

Circulation. 2026 Jul 14;154(2):156-177. doi: 10.1161/CIRCULATIONAHA.126.079274. Epub 2026 Jul 13.ABSTRACTPulmonary arterial hypertension (PAH) is a rare, progressive disease of the precapillary pulmonary arteries, characterized by fibroproliferative vascular remodeling, increased pulmonary vascular

M Marc Humbert

An Integrated Ecosystem for Cardiovascular Science and Health

No abstractCirculation. 2026 Jul 14;154(2):85-87. doi: 10.1161/CIRCULATIONAHA.126.080162. Epub 2026 Jul 13.NO ABSTRACTPMID:42441754 | DOI:10.1161/CIRCULATIONAHA.126.080162

K Karen E Joynt Maddox

Synergistic Effect of Hypertension and Smoking on Ischemic Stroke Risk: A Case-Control Study With Additive and Multiplicative Interaction Analysis

J Vis Exp. 2026 Jun 23;(232). doi: 10.3791/70381.ABSTRACTIschemic stroke remains a leading cause of death and disability worldwide. This single-center retrospective case-control study evaluated the independent and interactive effects of smoking, alcohol consumption, and traditional cardiovascular ri

J Jiaqi Wu

Cardiac Autonomic Dysfunction and Sudden Cardiac Death in Amyotrophic Lateral Sclerosis: Clinical Implications and Considerations for Care

Cardiol Rev. 2026 Jul 13. doi: 10.1097/CRD.0000000000001392. Online ahead of print.ABSTRACTAmyotrophic lateral sclerosis (ALS) is traditionally viewed as a motor neuron disease that progresses from muscular weakness to respiratory failure and death. Increasing evidence, however, demonstrates clinica

K Kelly Fisher

Obesity as a Clinical Disease: It's Time to Redefine It in Chile

No abstractRev Med Chil. 2026 Apr;154(4):605-607. doi: 10.4067/s0034-98872026000400605. Epub 2026 Jun 17.NO ABSTRACTPMID:42441686 | DOI:10.4067/s0034-98872026000400605

M Marion Guerrero-Wyss

Cardiac Amyloidosis Registry in Santiago, Chile (RAMICAR): Three-Year Follow-Up Results

Rev Med Chil. 2026 Apr;154(4):508-520. doi: 10.4067/s0034-98872026000400508. Epub 2026 Jun 17.ABSTRACTCardiac amyloidosis (CA) is characterized by extracellular protein deposition, generating ventricular hypertrophy, heart failure and arrhythmias. The main proteins involved are light chains (CA-AL)

J Jaime Álvarez G

Standardized Protocol for Intravascular Ultrasound-Guided Lithotripsy in Severely Calcified Coronary Lesions

J Vis Exp. 2026 Jun 23;(232). doi: 10.3791/71496.ABSTRACTSevere coronary artery calcification poses a clinical challenge during percutaneous coronary intervention, significantly increasing the risk of stent underexpansion and subsequent adverse cardiovascular events. While intravascular lithotripsy

J Jie Ruan

The role of von Willebrand factor in gastrointestinal angiodysplasia and obscure gi bleeding: a narrative review

Hematology. 2026 Dec 31;31(1):2702256. doi: 10.1080/16078454.2026.2702256. Epub 2026 Jul 13.ABSTRACTOBJECTIVE: Gastrointestinal bleeding (GIB) is a major cause of morbidity in von Willebrand disease (vWD), most commonly resulting from angiodysplasia. Current obscure gastrointestinal bleeding (OGIB)

O Ojan Ghodsi

Bibliometric and Two-Sample Mendelian Randomization Analyses of the Causal Relationship Between Hypertension and Erectile Dysfunction

J Vis Exp. 2026 Jun 26;(232). doi: 10.3791/71316.ABSTRACTHypertension (HT)-related erectile dysfunction (ED), a condition secondary to HT, is characterized by a persistent inability to achieve or maintain an erection sufficient for satisfactory sexual performance. This study aimed to systematically

J Jisheng Wang

Serum transthyretin as a staging biomarker in ATTR cardiomyopathy: promise, limitations, and the path forward

No abstractEur J Heart Fail. 2026 Jul 13:xuag200. doi: 10.1093/ejhf/xuag200. Online ahead of print.NO ABSTRACTPMID:42441529 | DOI:10.1093/ejhf/xuag200

V Valentina Allegro

Current Operating Procedure (COP) for the Treatment of Slow-Flow Vascular Malformations with Bleomycin Electrosclerotherapy (BEST)

J Vis Exp. 2026 Jun 26;(232). doi: 10.3791/70867.ABSTRACTBleomycin electrosclerotherapy (BEST) is an emerging, minimally invasive treatment for treating slow-flow vascular malformations. Following intralesional administration of bleomycin, reversible electroporation is applied to enhance drug uptake

M Miha Stabuc

Coexistence of Multiple Myeloma, Mast Cell Hyperplasia, and Low-Level Myeloid Blastocytosis: A Report of a Rare Case

Am J Case Rep. 2026 Jul 13;27:e952005. doi: 10.12659/AJCR.952005.ABSTRACTBACKGROUND Mast cell hyperplasia can present as systemic mastocytosis (SM) or reactive mast cell hyperplasia. Distinguishing between these 2 diseases is a critical challenge. Here, we report a rare case of concurrent mast cell

M Meng Yang

Reliable Creation of a Murine Abdominal Aortic Aneurysm Model Using Elastin Sensitization and Perivascular Elastase

J Vis Exp. 2026 Jun 26;(232). doi: 10.3791/72015.ABSTRACTDegradation of the elastic lamellar matrix in the abdominal aortic wall is a histopathologic feature of abdominal aortic aneurysms (AAA). Growing evidence implicates elastin degradation and related host immune responses in the pathogenesis of

R Rohan Basu

Identification of Candidate Biomarkers Associated with Mitochondrial Dysfunction and SUMOylation in Heart Failure Based on Bioinformatics Approaches

J Vis Exp. 2026 Jun 26;(232). doi: 10.3791/72265.ABSTRACTHeart failure (HF) presents a persistent clinical challenge. While SUMOylation and mitochondrial function are vital for cardiomyocyte health, their combined influence on HF remains elusive. Two HF-related datasets were downloaded from GEO. The

Z Zhe Chen

Intestinal Permeability Responses to Maximal and Submaximal Exercise in Individuals with Normal-Weight Obesity: An Exploratory Study

Am J Physiol Gastrointest Liver Physiol. 2026 Jul 13. doi: 10.1152/ajpgi.00124.2026. Online ahead of print.ABSTRACTIntestinal permeability may contribute to low-grade inflammation and cardiovascular disease (CVD). Despite health benefits, aerobic exercise acutely increases intestinal permeability in

B Bryant H Keirns

Aortic valve stenosis serum IGFBP2 mediates female-specific Evogliptin resistance in valve myofibroblasts

Cell Rep. 2026 Jul 13;45(7):117678. doi: 10.1016/j.celrep.2026.117678. Online ahead of print.ABSTRACTAortic valve stenosis (AVS) is a sexually dimorphic cardiovascular disease characterized by fibro-calcification of the aortic valve leaflet. Sex differences in AVS arise in part from sexually dimorph

B Brandon J Vogt

On the Road Again: Virtual Reality for Poststroke Rehabilitation

J Med Internet Res. 2026 Jul 13;28:e106124. doi: 10.2196/106124.ABSTRACTVirtual reality (VR) has a long history in stroke rehabilitation. In this News and Perspectives article, JMIR Correspondent Jenna Congdon reports on one person's journey back to driving after a stroke, highlighting the strengths

J Jenna Congdon

Impact of Menopause and Clinical Considerations in Patients With Inflammatory Bowel Disease

Gastroenterol Hepatol (N Y). 2026 Jul;22(4):196-204.ABSTRACTMenopause is marked by a natural decline in estrogen and progesterone that alters gut barrier integrity, immune regulation, and systemic inflammation. In women with inflammatory bowel disease (IBD), this interplay may result in increased sy

D Dhruvi Shah