Harnessing data science to control non-communicable diseases in Africa: a systematic review and gap analysis

Commun Med (Lond). 2026 Jul 16;6(1):397. doi: 10.1038/s43856-025-01272-0.ABSTRACTBACKGROUND: Data science methods can provide novel and pragmatic approaches for preventing and controlling non-communicable diseases (NCDs) in Africa. This study highlights current efforts, opportunities, and challenges

A Akinkunmi Paul Okekunle

Integration of molecular docking, molecular dynamics simulations, and free energy calculations identifies a novel flavonoid glycoside as a PCSK9 inhibitor for hypercholesterolemia

Sci Rep. 2026 Jul 16. doi: 10.1038/s41598-026-60821-2. Online ahead of print.ABSTRACTProprotein convertase subtilisin/kexin type 9 (PCSK9) significantly influences plasma low-density lipoprotein cholesterol (LDL-C) homeostasis by promoting the degradation of LDL receptors. While monoclonal antibody

Y Yanwei Wang

Transparent chest radiograph foundation model enables explainable human disease profiling

NPJ Digit Med. 2026 Jul 16. doi: 10.1038/s41746-026-02990-y. Online ahead of print.ABSTRACTChest radiography (CXR) is widely accessible, and its ability to capture subtle manifestations of systemic disease remains underexplored. We developed a contrastively pretrained multimodal CXR foundation model

C Chin Lin

Impact of changes in sarcopenia status on incident cardiovascular disease and mortality in older adults

Sci Rep. 2026 Jul 16. doi: 10.1038/s41598-026-61764-4. Online ahead of print.ABSTRACTSarcopenia is an independent risk factor for cardiovascular disease (CVD) and mortality. However, the impact of longitudinal changes in sarcopenia remains unclear. We investigated the relationship between changes in

N Na-Noom Jeong

Risk factors associated with cardiovascular hospital admissions and all-cause mortality in cancer patients treated with immune checkpoint inhibitors

Support Care Cancer. 2026 Jul 17;34(8):770. doi: 10.1007/s00520-026-10983-6.ABSTRACTPURPOSE: Immune checkpoint inhibitors (ICIs) are highly effective cancer therapies. However, they are associated with considerable adverse cardiovascular (CV) outcomes. We investigated the risk factors for CV hospita

J Joshua D Bennetts

Conceptual framework and expert guidance on intrapancreatic fat deposition: the Melbourne consensus

Nat Rev Gastroenterol Hepatol. 2026 Jul 16. doi: 10.1038/s41575-026-01224-6. Online ahead of print.ABSTRACTIntrapancreatic fat deposition (IPFD) has garnered appreciable attention across diverse medical disciplines amid the rising global burden of pancreatitis, pancreatic cancer and type 2 diabetes

M Maxim S Petrov

Outcomes of thoracic endovascular aortic repair. 10-years follow-up in LATAM population: experience from a tertiary care center in Mexico

Arch Cardiol Mex. 2026 Jul 16. doi: 10.24875/ACM.25000084. Online ahead of print.ABSTRACTBACKGROUND: Thoracic aortic pathologies comprise a broad group of conditions affecting one or more layers of the aorta, some of which are known to be life-threatening. The development of thoracic aortic endovasc

J Jhonathan Uribe-González

GMP-compliant production, validation and dosimetry of clinical grade [18F]3-(3-fluoropropyl)-2-phenyl-2,3-dihydrobenzo[d]thiazole ([18F]FPBT) for oxidative stress PET imaging

Br J Pharmacol. 2026 Jul 16. doi: 10.1111/bph.70593. Online ahead of print.ABSTRACTBACKGROUND AND PURPOSE: Oxidative stress plays a critical role in the pathophysiology of various diseases, yet current methods for its non-invasive detection remain limited. This study aimed to systematically validate

H Hua Zhang

Floating aortic arch thrombus revealing an occult ascending aortic dissection: a case report

Arch Cardiol Mex. 2026 Jul 16. doi: 10.24875/ACM.26000029. Online ahead of print.ABSTRACTFloating thrombus of the thoracic aorta is an uncommon but potentially catastrophic source of systemic embolization. Although most cases are associated with structural abnormalities of the aortic wall, pre-opera

J Jose D Bran

Heart Failure in Menopause: An Emerging Cardiovascular Challenge

No abstractHeart Lung Circ. 2026 Jul 16:S1443-9506(26)00409-9. doi: 10.1016/j.hlc.2026.06.002. Online ahead of print.NO ABSTRACTPMID:42463401 | DOI:10.1016/j.hlc.2026.06.002

S Shaun Khanna

Overlap Between Heart Failure and Menopause: Diagnostic Challenges and Clinical Implications

Heart Lung Circ. 2026 Jul 16:S1443-9506(26)00417-8. doi: 10.1016/j.hlc.2026.05.011. Online ahead of print.ABSTRACTHeart failure and menopause commonly coexist in middle-aged women, but overlapping symptomatology often complicates diagnosis. Moreover, physiological changes during menopause and normal

T Timothy Nathan Kwan

Cardioneural and accessory atrioventricular pathway ablation for vagally mediated atrial fibrillation in PRKAG2 syndrome

Heart Lung. 2026 Jul 16:102882. doi: 10.1016/j.hrtlng.2026.102882. Online ahead of print.ABSTRACTCardioneural ablation (CNA) is an emerging strategy for vagally mediated arrhythmias, but its role in patients with underlying conduction system disease remains undefined. Here, a young patient with PRKA

C Caroline B Ledet

Enhanced Recovery After Cardiac Surgery: A Bibliometric Analysis With Emphasis on Perioperative and Anesthetic Practice

J Cardiothorac Vasc Anesth. 2026 Jun 25:S1053-0770(26)00507-0. doi: 10.1053/j.jvca.2026.06.034. Online ahead of print.ABSTRACTOBJECTIVES: To systematically characterize the global research landscape and emerging trends of enhanced recovery after cardiac surgery (ERACS).DESIGN: Bibliometric analysis.

S Shuo Huang

Characterising heterogeneity in the host response to supplemental nitric oxide therapy in patients undergoing cardiac surgery with cardiopulmonary bypass

No abstractBr J Anaesth. 2026 Jul 16:S0007-0912(26)00432-0. doi: 10.1016/j.bja.2026.05.028. Online ahead of print.NO ABSTRACTPMID:42463373 | DOI:10.1016/j.bja.2026.05.028

S Sylvia Ranjeva

Bridging the gap in familial hypercholesterolemia: An adult care perspective on transitioning emerging adults toward lifelong cardiovascular prevention

J Clin Lipidol. 2026 Jun 22:S1933-2874(26)00405-8. doi: 10.1016/j.jacl.2026.06.015. Online ahead of print.ABSTRACTBACKGROUND: Familial hypercholesterolemia (FH) confers lifelong elevation in low-density lipoprotein-cholesterol (LDL-C) and markedly increases the risk for premature atherosclerotic car

S Shanice Glasco

First real-world experience with inclisiran in Spain: Efficacy, safety, and prescription patterns in clinical practice

Clin Investig Arterioscler. 2026 Jul 16:500957. doi: 10.1016/j.arteri.2026.500957. Online ahead of print.ABSTRACTBACKGROUND: Low-density lipoprotein cholesterol (LDL-C) is a key causal factor in atherosclerotic cardiovascular disease. Although statins remain the cornerstone of treatment, their use i

A Alvaro Velasco

Global, regional, and national high LDL-cholesterol-related disease burden: an updated analysis of the global burden of disease study 2021

Nutr Metab Cardiovasc Dis. 2026 Jul 8:104861. doi: 10.1016/j.numecd.2026.104861. Online ahead of print.ABSTRACTBACKGROUND AND AIMS: High low-density lipoprotein cholesterol (HLDL-C) levels are independently associated with adverse cardiovascular events. Based on the latest Global Burden of Disease S

Z Zechao Xu

The role of the Mediterranean diet in secondary cardiovascular disease prevention: a systematic review and meta-analysis of cohort studies

Nutr Metab Cardiovasc Dis. 2026 Jul 1:104854. doi: 10.1016/j.numecd.2026.104854. Online ahead of print.ABSTRACTAIMS: Although the Mediterranean diet is well established for primary cardiovascular disease (CVD) prevention, its role in secondary prevention is less evidence-based. This systematic revie

E Evdoxia Gitsi

Isolation, expansion, and identification of the perivascular adipose-derived mesenchymal stem cells from rat aortas

Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2026 Jul;42(7):607-615.ABSTRACTObjective To establish a method for isolating and expanding perivascular adipose-derived mesenchymal stem cells (PV-ADSC) from rat aortas and to provide a reliable cellular model for investigating vascular remodeling and the related

H Huagen Ma

Associations of [18F]PI-2620 Binding with Memory and Phosphorylated Tau 217 in Cognitively Unimpaired Older Adults

J Nucl Med. 2026 Jul 16:jnumed.125.271927. doi: 10.2967/jnumed.125.271927. Online ahead of print.ABSTRACT[18F]PI-2620 is a second-generation tau PET tracer that may detect early tau accumulation in aging. We investigated whether temporal lobe [18F]PI-2620 binding is associated with age, sex, genetic

A Anne Maass

GLP-1 receptor agonists in systemic lupus erythematosus: a scoping review

RMD Open. 2026 Jul 16;12(3):e007037. doi: 10.1136/rmdopen-2026-007037.ABSTRACTOBJECTIVE: Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) are increasingly recognised for benefits beyond glycaemic control, including anti-inflammatory, anti-atherogenic and potential immunomodulatory effects. Give

R Robin Sia

Beyond Resnick and Niwayama: a structured narrative literature review on the clinical and imaging phenotypes of diffuse idiopathic skeletal hyperostosis (DISH)

RMD Open. 2026 Jul 16;12(3):e006809. doi: 10.1136/rmdopen-2026-006809.ABSTRACTSince 1975, the Resnick and Niwayama classification criteria have served as the standard framework for defining diffuse idiopathic skeletal hyperostosis (DISH) in research. These criteria predominantly identify advanced di

A Amir Bieber

Optimising Health Literacy and Access (Ophelia) in Florence, Italy: a cluster analysis to guide cardiovascular prevention among perimenopausal and postmenopausal women in a vulnerable urban setting

BMJ Open. 2026 Jul 16;16(7):e115177. doi: 10.1136/bmjopen-2025-115177.ABSTRACTBACKGROUND: Cardiovascular risk increases markedly in perimenopausal and postmenopausal women and social disadvantage can intensify barriers to prevention. In these settings, limited health literacy may further restrict wo

C Claudia Cosma

Personalised approach to hypertension treatment: protocol for the HYPERMARKER randomised controlled trial

BMJ Open. 2026 Jul 16;16(7):e117869. doi: 10.1136/bmjopen-2026-117869.ABSTRACTINTRODUCTION: Blood pressure treatment response is variable in individual patients, and the choice of medical therapy is often dependent on clinician experience. Treatment choices could be personalised by patient empowerme

M Matthew Chapman