Cardiovasc Diabetol. 2026 May 14. doi: 10.1186/s12933-026-03209-w. Online ahead of print.ABSTRACTBACKGROUND AND AIMS: Reducing plasma levels of low-density lipoprotein cholesterol (LDL-C) is the cornerstone in the prevention of coronary artery disease (CAD) but may also increase risk of type 2 diabe
Nutr Metab (Lond). 2026 May 14. doi: 10.1186/s12986-026-01135-y. Online ahead of print.ABSTRACTBACKGROUND: Recent studies have focused on the relationship between the Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) diet and the risk of chronic diseases and mortality. The present s
Lipids Health Dis. 2026 May 14. doi: 10.1186/s12944-026-02945-y. Online ahead of print.ABSTRACTBACKGROUND: This study aimed to investigate whether plasma fatty acid composition is associated with incident atherosclerotic cardiovascular disease (ASCVD) and whether it modifies the cardiovascular risk
Lipids Health Dis. 2026 May 14. doi: 10.1186/s12944-026-02976-5. Online ahead of print.ABSTRACTBACKGROUND: Familial hypercholesterolemia (FH) is a common, autosomal semi-dominant inherited disorder causing premature cardiovascular disease. However, it remains underdiagnosed, especially in community
BMC Med. 2026 May 14. doi: 10.1186/s12916-026-04938-1. Online ahead of print.ABSTRACTBACKGROUND: Global flagship initiatives increasingly advocate for proactive health maintenance to alleviate the growing burden on reactive, disease-focused healthcare systems. Precision prevention is conceived as th
BMC Med Imaging. 2026 May 14;26(1):253. doi: 10.1186/s12880-026-02379-z.ABSTRACTBACKGROUND: Coronary Computed Tomography Angiography (CCTA) is an established tool for assessing coronary artery disease. CCTA determined total coronary artery plaque volume predicts cardiovascular events, but manual qua
BMC Public Health. 2026 May 14. doi: 10.1186/s12889-026-27724-3. Online ahead of print.ABSTRACTBACKGROUND: Cardio-renal-metabolic diseases (CRMDs), including cardiovascular disease, chronic kidney disease, and type 2 diabetes, often co-occur and progress from a healthy state to first CRMD (FCRMD), c
BMC Cardiovasc Disord. 2026 May 14. doi: 10.1186/s12872-026-05822-9. Online ahead of print.ABSTRACTBACKGROUND: Myocardial infarction (MI), one of the most severe cardiovascular diseases, is influenced by altered macrophage status and metabolic reprogramming (MR), yet the mechanisms of their crosstal
No abstractJ Gen Intern Med. 2026 May 14. doi: 10.1007/s11606-026-10414-6. Online ahead of print.NO ABSTRACTPMID:42135582 | DOI:10.1007/s11606-026-10414-6
Nicotinamide adenine dinucleotide (NAD^(+)) levels in blood and tissues are widely proposed to decline with age, yet evidence in human blood is inconsistent. Using a rigorously validated ultra-high-performance liquid chromatography coupled with high-resolution mass spectrometry system that accounts
Cardiovasc Eng Technol. 2026 May 14. doi: 10.1007/s13239-026-00840-2. Online ahead of print.ABSTRACTPURPOSE: Restoration of physiological aortic hemodynamics is a crucial therapeutic target after transcatheter aortic valve implantation (TAVI). However, quantifying this restoration is challenging, pa
Sci Rep. 2026 May 14. doi: 10.1038/s41598-026-44492-7. Online ahead of print.ABSTRACTEmpagliflozin, a sodium-glucose cotransporter-2 (SGLT2) inhibitor, has demonstrated cardioprotective effects beyond glycemic control. Empagliflozin has anti-inflammatory and antioxidant effects in long-term administ
Sci Rep. 2026 May 14. doi: 10.1038/s41598-026-45582-2. Online ahead of print.ABSTRACTThe spot urinary potassium-to-creatinine (uK/uCr) ratio has been proposed as a surrogate for 24-h potassium excretion, but its clinical determinants and prognostic significance in heart failure (HF) remain unclear.
Nat Commun. 2026 May 14. doi: 10.1038/s41467-026-72693-1. Online ahead of print.ABSTRACTWearable technologies have the potential to transform ambulatory and at-home hemodynamic monitoring by providing continuous assessments of cardiovascular health metrics and guiding clinical management. However, e
Signal Transduct Target Ther. 2026 May 14;11(1):179. doi: 10.1038/s41392-026-02656-x.ABSTRACTHeart disease is characterized by stress-induced endoreplication preceding pathological cardiomyocyte overgrowth, yet the upstream regulatory mechanisms linking tissue hypoxia to aberrant cellular growth rem
J Proteome Res. 2026 May 14. doi: 10.1021/acs.jproteome.6c00103. Online ahead of print.ABSTRACTDrug-induced cardiovascular risk is one of the primary concerns in drug development and clinical practice. Meanwhile, drugs can also alter the gut microbiome, the disturbance of which is correlated with ca
Cardiovasc Res. 2026 May 14:cvag109. doi: 10.1093/cvr/cvag109. Online ahead of print.ABSTRACTMonocytes and macrophages are critically involved in the pathogenesis of atherosclerotic cardiovascular disease (ASCVD). Accumulating evidence indicates that monocytes and macrophages can develop innate immu
J Clin Lipidol. 2026 Apr 27:S1933-2874(26)00126-1. doi: 10.1016/j.jacl.2026.04.022. Online ahead of print.ABSTRACTThe recent 2026 American College of Cardiology/American Heart Association Multisociety Guideline on the Management of Dyslipidemia joins the growing international consensus that lipoprot
No abstractJ Formos Med Assoc. 2026 May 14:S0929-6646(26)00525-5. doi: 10.1016/j.jfma.2026.05.028. Online ahead of print.NO ABSTRACTPMID:42135137 | DOI:10.1016/j.jfma.2026.05.028
Heart Lung Circ. 2026 May 14:S1443-9506(26)00248-9. doi: 10.1016/j.hlc.2026.04.005. Online ahead of print.ABSTRACTFrailty is prevalent in older adults and affects up to half of people living with heart failure, contributing to functional decline, hospitalisation, poor quality of life, and mortality.
Trends Biotechnol. 2026 May 15:S0167-7799(26)00176-9. doi: 10.1016/j.tibtech.2026.04.022. Online ahead of print.ABSTRACTCardiovascular devices such as stents, grafts, and bioprosthetic valves are vital treatments for advanced disease, yet long-term outcomes remain limited by chronic inflammation and
Clin Chem. 2026 May 15:hvag030. doi: 10.1093/clinchem/hvag030. Online ahead of print.ABSTRACTBACKGROUND: Sex-specific diagnostic thresholds for high-sensitivity cardiac troponin (hs-cTn) assays are recommended by international guidelines for the diagnosis of myocardial infarction (MI). We assessed t
No abstractEur J Prev Cardiol. 2026 May 14:zwag266. doi: 10.1093/eurjpc/zwag266. Online ahead of print.NO ABSTRACTPMID:42135061 | DOI:10.1093/eurjpc/zwag266
Eur Heart J. 2026 May 15:ehag353. doi: 10.1093/eurheartj/ehag353. Online ahead of print.ABSTRACTLeft main disease represents one of the most complex lesion subsets for percutaneous coronary intervention, associated with an increased risk of serious late complications. The recent endorsement of intra
