Application Mechanisms and Clinical Prospects of Brain-Computer Interface Technology in Radiation-Induced Brain Injury

Cell Mol Neurobiol. 2026 Jun 11. doi: 10.1007/s10571-026-01758-y. Online ahead of print.ABSTRACTRadiation-induced brain injury (RIBI) is a common complication of radiotherapy that leads to neurological symptoms, significantly impairing patients' daily functioning and long-term rehabilitation. Conseq

R Ruijun Xu

Discrete subaortic stenosis: prognostic value of the left ventricular outflow tract gradient and implications for earlier surgical intervention

World J Pediatr. 2026 Jun 11. doi: 10.1007/s12519-026-01048-z. Online ahead of print.ABSTRACTBACKGROUND: The optimal timing of surgery for discrete subaortic stenosis (DSS) is controversial due to limited evidence from large-scale trials. This study aimed to identify prognostic factors and reassess

Y Yu-Tong Jiang

Comparative Efficacy of Nutraceuticals on Endothelial Function: A Systematic Review and Network Meta-Analysis

Curr Atheroscler Rep. 2026 Jun 12;28(1):62. doi: 10.1007/s11883-026-01436-w.ABSTRACTPURPOSE OF REVIEW: This network meta-analysis (NMA) compares the efficacy of dietary interventions in improving flow mediated dilation (FMD) as a measure of endothelial function among individuals with cardiovascular

M Mostafa Norouzzadeh

Longitudinal Trajectories and Predictors of Health-Related Quality of Life in Systemic Lupus Erythematosus: A 2-Year Longitudinal Cohort Study

Rheumatol Ther. 2026 Jun 12. doi: 10.1007/s40744-026-00864-z. Online ahead of print.ABSTRACTINTRODUCTION: Health-related quality of life (HRQoL) is a critical patient-reported outcome in systemic lupus erythematosus (SLE). We aimed to evaluate longitudinal trajectories of HRQoL and identify associat

W Wan-Yun Hsu

Elevated Plasma T-LAK cell-originated protein kinase Owned the Potential for Predicting Favorable Outcomes in Acute Ischemic Stroke Patients

Cell Mol Neurobiol. 2026 Jun 11. doi: 10.1007/s10571-026-01765-z. Online ahead of print.ABSTRACTT-lymphokine-activated killer-cell-originated protein kinase (TOPK), was widely overexpressed in various malignant tumors, and played critical roles in their growth, differentiation and metastasis. Howeve

L Lingzhi Li

Skeletal-muscle-targeted non-viral delivery of full-length DMD mRNA for Duchenne muscular dystrophy

Nat Biomed Eng. 2026 Jun 11. doi: 10.1038/s41551-026-01689-5. Online ahead of print.ABSTRACTDuchenne muscular dystrophy (DMD) is a severe, progressive muscle-wasting disorder caused by mutations in the DMD gene, which encodes dystrophin. Although gene therapy using viral vectors has shown promise fo

Y Yu Tian

Embeddings of clinical codes enable knowledge-grounded AI in medicine

NPJ Digit Med. 2026 Jun 11. doi: 10.1038/s41746-026-02664-9. Online ahead of print.ABSTRACTStandardization of electronic health records (EHRs) has enabled the use of clinical codes in AI. We introduce ClinVec, an embedding store that provides embeddings for 153,166 clinical codes and concepts across

R Ruth Johnson

IoMT-Blockchain framework for secure and real-time heart disease monitoring using hybrid black-winged optimized spherical structural graph convolutional neural networks

Sci Rep. 2026 Jun 11. doi: 10.1038/s41598-026-57620-0. Online ahead of print.ABSTRACTCardiovascular diseases are a primary global health concern, requiring continuous monitoring and accurate diagnostic mechanisms for early detection and prevention. The integration of the Internet of Medical Things (

P P Bhuvaneshwari

Four-dimensional left ventricular motion clustering reveals cardiovascular phenotypes at population scale

Sci Rep. 2026 Jun 11. doi: 10.1038/s41598-026-56151-y. Online ahead of print.ABSTRACTCharacterisation of the motion dynamics of the left ventricle is key to understanding pathophysiological mechanisms and transitions from health to disease. Conventional volumetric assessments of the heart using imag

P Pierre-Raphael Schiratti

Plasma proteomics of sleep traits reveals systemic immune-metabolic pathways and genetically prioritized proteins

Mol Psychiatry. 2026 Jun 11. doi: 10.1038/s41380-026-03678-1. Online ahead of print.ABSTRACTThe plasma proteomic signatures of sleep disturbance remain poorly characterized. Using data from 43,709 predominantly European-ancestry, middle-aged and older UK Biobank participants, we depict a large-scale

H Han Chen

TM4SF1 mediates YAP/TAZ regulation of coronary artery formation

Sci Rep. 2026 Jun 11. doi: 10.1038/s41598-026-57461-x. Online ahead of print.ABSTRACTAlthough the role of YAP/TAZ in mediating VEGF-driven angiogenesis is well established, their downstream effectors in coronary artery development remain elusive. In this study, we identify TM4SF1 as a novel downstre

Y Yuan Fang

Predictive value of aortic propagation velocity for cardiovascular events in asymptomatic individuals with elevated ASCVD risk

Sci Rep. 2026 Jun 11. doi: 10.1038/s41598-026-56810-0. Online ahead of print.ABSTRACTPrediction of cardiovascular diseases (CVD) is a challenge that cardiologists have always faced all the times. Aortic propagation velocity (APV) is an echocardiography index that can be helpful with this regard; how

L Leila Bigdelu

Particulate matter 2.5 induced inflammatory responses and metabolic alterations in human monocytes

Fine particulate matter 2.5 (PM(2.5)) is linked to rising cases of respiratory, cardiovascular, and immune-mediated diseases and increased hospitalizations in non-respiratory patients. Chiang Mai Province in Northern Thailand, faces seasonal severe PM(2.5) pollution, but its impact on immune respons

N Naunpun Sangphech

Daytime impairment and depressive symptoms in patients with obstructive sleep apnea and coexisting insomnia symptoms: A cross-sectional study from a Caribbean sleep center

Sleep Health. 2026 Jun 11:S2352-7218(26)00100-2. doi: 10.1016/j.sleh.2026.05.005. Online ahead of print.ABSTRACTOBJECTIVES: This study aimed to examine the association between insomnia symptoms and daytime functioning, depressive symptoms, and cardiovascular comorbidities among patients evaluated fo

M Moustapha Agossou

The LIFE study: a cross-sectional study protocol for LIfestyle risk Factors for chronic disease across the stagEs of reproductive ageing

BMJ Open. 2026 Jun 11;16(6):e106377. doi: 10.1136/bmjopen-2025-106377.ABSTRACTINTRODUCTION: The dynamic physiological and hormonal changes through the menopause transition predispose women to an increased risk of chronic diseases including cardiovascular disease, metabolic disease, depression and de

L Laura E Pernoud

Translation and validation of the Norwegian ABCD Risk Questionnaire to assess cardiovascular disease knowledge and risk perception prior to myocardial infarction

BMJ Open. 2026 Jun 11;16(6):e118713. doi: 10.1136/bmjopen-2026-118713.ABSTRACTOBJECTIVES: The aim of this study was to translate the Attitudes and Beliefs about Cardiovascular Disease (ABCD) Risk Questionnaire into Norwegian and assess its psychometric properties among individuals with a history of

V Virginia De Martin Topranin

Effect of supplemental hydrocortisone during stress in prednisolone-induced adrenal insufficiency: a study protocol for a multicentre, randomised, double-blinded, placebo-controlled clinical trial on health-related quality of life in patients with polymyalgia rheumatica/giant cell arteritis on low-dose prednisolone treatment (the RESCUE study)

BMJ Open. 2026 Jun 11;16(6):e113110. doi: 10.1136/bmjopen-2025-113110.ABSTRACTINTRODUCTION: Patients on low-dose prednisolone may develop adrenal insufficiency causing reduced health-related quality of life (HRQoL) and increased risk of adrenal crisis. This study examines whether supplemental hydroc

S Stina Willemoes Borresen

Identifying social determinants of health subgroups and their associations with health outcomes in a prospective US adult COVID-19 cohort: an analysis of the INSPIRE registry

BMJ Open. 2026 Jun 11;16(6):e105749. doi: 10.1136/bmjopen-2025-105749.ABSTRACTOBJECTIVE: To identify subgroups with similar social determinants of health (SDOH) characteristics using latent class analysis (LCA) and examine their associations with physical and mental health, cognitive function and mi

Y Yohali Burrola-Mendez

Mechanism of PCSK9-Mediated Macrophage Activation via the CAP1/NF-kappaB Pathway in CAWS-Induced Kawasaki Disease Vasculitis

IUBMB Life. 2026 Jun;78(6):e70119. doi: 10.1002/iub.70119.ABSTRACTProprotein convertase subtilisin/kexin type 9 (PCSK9) acts as a pleiotropic modulator of inflammation. This study aimed to investigate the role and underlying mechanism of PCSK9 in Kawasaki disease (KD)-associated vasculitis. A Candid

H Hao Zhang

Aortitis accelerates the growth rate of thoracic aortic aneurysms

RMD Open. 2026 Jun 11;12(2):e006933. doi: 10.1136/rmdopen-2026-006933.ABSTRACTBACKGROUND: Thoracic aortic aneurysms (TAA) are predominantly degenerative. Non-infectious inflammatory aortitis, including giant cell arteritis (GCA), Takayasu arteritis and clinically isolated aortitis (CIA), represents

A Antoine Benichou

Measuring efferocytosis by intraperitoneal clearance assay

Methods Cell Biol. 2026;208:203-219. doi: 10.1016/bs.mcb.2026.02.006. Epub 2026 Mar 3.ABSTRACTEfferocytosis is a critical process by which phagocytes identify, engulf and clear apoptotic cells, thereby preserving immune tolerance and tissue homeostasis. While in vitro assays have advanced our unders

C Caitlin L Vella

A patient with cardiac and cerebrovascular comorbidity

J Vasc Nurs. 2026 Jun;44(2):180-186. doi: 10.1016/j.jvn.2026.03.002. Epub 2026 Apr 2.ABSTRACTThis case report highlights the experience of formulating nurse-led health education or intervention for a patient with cardiovascular and cerebrovascular comorbidity. Nursing care was guided by Omaha system

Y Yanrong Li

Role of nursing in the assessment of Peripheral Artery Disease: Comparison of two ankle to arm Index methods in patients with Diabetes

J Vasc Nurs. 2026 Jun;44(2):166-171. doi: 10.1016/j.jvn.2026.03.003. Epub 2026 Apr 7.ABSTRACTAIMS: To compare the clinical implications of the new International Working Group on the Diabetic Foot (IWGDF) criterion for calculating the ankle-brachial index (ABI), which uses the lowest systolic blood p

E Esther Chicharro-Luna

Sex-specific associations between midlife body mass index and later-life left atrial enlargement in the Hordaland health study

Heart. 2026 Jun 11:heartjnl-2025-327623. doi: 10.1136/heartjnl-2025-327623. Online ahead of print.ABSTRACTBACKGROUND: Increased body mass index (BMI) leads to blood volume increase and left atrial enlargement (LAE). It is not known whether BMI and BMI change in midlife predispose to LAE later in lif

A Annabel Eide Ohldieck