Cardiac magnetic resonance imaging in coronary heart disease: IQWiG Reports - Commission No. D24-02

Cologne (Germany): Institute for Quality and Efficiency in Health Care (IQWiG); 2026 Feb 22.ABSTRACTRESEARCH QUESTION: The aim of this report is toassess the benefit of diagnostics using cardiac magnetic resonance imaging as part of a diagnostic strategy, compared with a diagnostic strategy without

I Institute for Quality and Efficiency in Health Care (IQWiG)

Biallelic LAMP3 Variants in Five Families with Interstitial Lung Disease: Evidence of a Disease-Gene Association

Genet Med. 2026 Feb 3:102531. doi: 10.1016/j.gim.2026.102531. Online ahead of print.ABSTRACTPURPOSE: Genetic causes of surfactant dysfunction are associated with childhood interstitial lung disease (chILD). Lysosome-associated membrane glycoprotein 3 (LAMP3) is highly expressed within lamellar bodie

L Laura A Keehan

Cholesterol Lowering Alone Fails to Reverse Atherosclerotic Plaque Necrosis, Granulopoiesis, and Neurovascular Neutrophils in Middle-Aged Mice

FASEB J. 2026 Feb 28;40(4):e71508. doi: 10.1096/fj.202503638RR.ABSTRACTCholesterol lowering through diet, lifestyle, and pharmacologic therapy remains central for limiting atherosclerosis and prevention of major adverse cardiovascular events. Yet, 33%-50% of individuals on lipid-lowering therapy con

O Olivia Gannon

Identification of Mitophagy-Related Genes With Diagnostic Value in Atherosclerosis Using Bioinformatics Analysis and Experiment Validation

Chem Biol Drug Des. 2026 Feb;107(2):e70260. doi: 10.1111/cbdd.70260.ABSTRACTAtherosclerosis (AS) is a chronic inflammatory condition with complex molecular underpinnings, where mitophagy-selective mitochondrial autophagy-plays a critical yet poorly defined role. By integrating bulk and single-cell R

Z Zhe Chen

Emerging insights into enhancer RNAs: biogenesis, function, mechanism, and disease implication

Brief Bioinform. 2026 Jan 7;27(1):bbaf700. doi: 10.1093/bib/bbaf700.ABSTRACTIn current years, the molecular mechanisms through which enhancer-derived noncoding RNAs-enhancer RNAs (eRNAs) have been increasingly elucidated. eRNAs are not mere as transcript products but considered as a marker of active

M Meiqian Qiu

ETV2-ECSCR-mTOR pathways regulate reprogramming to the endothelial lineage

Stem Cells. 2026 Feb 6:sxaf075. doi: 10.1093/stmcls/sxaf075. Online ahead of print.ABSTRACTETV2 is a pioneer factor that regulates cell fate decisions and direct reprogramming of the endothelial lineage. While ETV2 drives the cell fate conversion through epigenetic remodeling, its downstream targets

Y Young Geun Choi

Inactivation of the Phosphatase Activity of Soluble Epoxide Hydrolase Modulates SIRT3 and Attenuates Experimental Pulmonary Hypertension

Compr Physiol. 2026 Feb;16(1):e70108. doi: 10.1002/cph4.70108.ABSTRACTINTRODUCTION: Pulmonary hypertension (PH) is a severe cardiovascular disorder characterized by elevated pulmonary artery pressure caused by remodeling of the pulmonary circulation. This study aimed to investigate the role of the s

M Matthieu Leuillier

Heart rate variability changes in adolescents following surgical correction of aortic coarctation: Persistent autonomic alterations

Physiol Rep. 2026 Feb;14(3):e70769. doi: 10.14814/phy2.70769.ABSTRACTHeart rate variability (HRV) is a sensitive marker of autonomic regulation. This study examined adolescents in the long-term postoperative period after early surgical correction of aortic coarctation (CoA) compared with age-matched

O O V Shevaldova

Coronary Artery Bypass Grafting in the Presence of Severe Hyperthyroidism: A Case Report

Am J Case Rep. 2026 Feb 7;27:e950442. doi: 10.12659/AJCR.950442.ABSTRACTBACKGROUND In coronary artery bypass grafting, hyperthyroidism with autoantibodies, as seen in Basedow disease, is uncommon and rarely leads to severe thyrotoxicosis. However, surgery can trigger this condition, and documented c

A Akie Shimada

The role of plant-food derived bioactives in modulating the gut microbiome, inflammation and metabolic syndrome: Regulatory and market dynamics

Food Res Int. 2026 Mar 1;227:118243. doi: 10.1016/j.foodres.2025.118243. Epub 2025 Dec 27.ABSTRACTThe global increase in metabolic disorders including obesity, type 2 diabetes (T2DM), and cardiovascular disease (CVD) highlights the need for adjunctive strategies beyond conventional pharmacotherapy.

B Benjamin Ovai

Procyanidin C1 from hawthorn modulates metabolic-inflammatory axis to combat vascular senescence in atherosclerosis

Food Res Int. 2026 Mar 1;227:118224. doi: 10.1016/j.foodres.2025.118224. Epub 2025 Dec 26.ABSTRACTThe global aging crisis has increased the risk of atherosclerosis (AS), positioning vascular senescence as a critical therapeutic target. Procyanidin C1 (PCC1), a bioactive polyphenol from hawthorn, dem

M Min Li

Identification and validation of quinoa-derived ACE inhibitory peptides via multidimensional molecular descriptor clustering

Food Res Int. 2026 Mar 1;227:118300. doi: 10.1016/j.foodres.2025.118300. Epub 2025 Dec 30.ABSTRACTHypertension, a major global health issue, is closely associated with the overactivation of angiotensin-converting enzyme (ACE). Food-derived ACE inhibitory peptides are gaining increasing attention as

W Wenyuan Zhang

Impact of a low-carbohydrate diet on cardiometabolic parameters in individuals with and without diabetes: An 8-year longitudinal study within the ELSA-Brasil cohort

Nutr Clin Pract. 2026 Feb 6. doi: 10.1002/ncp.70099. Online ahead of print.ABSTRACTBACKGROUND: Low-carbohydrate diets (LCDs) are widely adopted for metabolic management, but their long-term cardiometabolic effects in diverse populations remain unclear. We aimed to evaluate the association between se

L Leticia Batista de Azevedo

Rationale and Design of the Cooperative Program for ImpLementation of Optimal Therapy in Heart Failure

Clin Cardiol. 2026 Feb;49(2):e70222. doi: 10.1002/clc.70222.ABSTRACTBACKGROUND: Despite overwhelming evidence of clinical benefit for patients with heart failure (HF), the uptake of guideline-directed medical therapies (GDMT) has been slow. Collaborative approaches are critically needed to improve a

A Alexander J Blood

Effects of Five-Element Music Therapy on Depression Symptoms After Stroke: A Meta-Analysis of Randomized Controlled Trials

Int J Nurs Pract. 2026 Feb;32(1):e70112. doi: 10.1111/ijn.70112.ABSTRACTBACKGROUND: Depression symptoms are prevalent and persistent psychological problems after a stroke. Five-element music therapy has been used to improve depression symptoms in stroke patients, but the effects have not yet been un

T Ting Yang

Neighborhood Influences on Cardiovascular Health: A Concept Mapping Study With Young Black Men Living in Southern Black Communities

Am J Mens Health. 2026 Jan-Feb;20(1):15579883261418250. doi: 10.1177/15579883261418250. Epub 2026 Feb 6.ABSTRACTCardiovascular health (CVH) is both a concept and a measure that refers to health behaviors and clinical factors that help prevent cardiovascular disease (CVD). The neighborhood environmen

S Samuel L K Baxter

The association between the glucose-lipid metabolism index and the cardiovascular disease prevalence of prediabetes and diabetes participants: evidence from NHANES 2001-2018

No abstractBMC Endocr Disord. 2026 Feb 6. doi: 10.1186/s12902-026-02169-2. Online ahead of print.NO ABSTRACTPMID:41652592 | DOI:10.1186/s12902-026-02169-2

R Ruishan Liu

Use of anti-nucleocapsid antibody detection as a marker of SARS-CoV-2 infection in healthcare professionals: a longitudinal seroprevalence study at a university hospital in Catalonia, Spain

No abstractBMC Infect Dis. 2026 Feb 6. doi: 10.1186/s12879-026-12796-8. Online ahead of print.NO ABSTRACTPMID:41652586 | DOI:10.1186/s12879-026-12796-8

M Miquel Micó

Association of long cardiac troponin T forms with adverse long-term outcomes in patients with advanced chronic kidney disease

BMC Nephrol. 2026 Feb 6. doi: 10.1186/s12882-026-04803-6. Online ahead of print.ABSTRACTBACKGROUND: Commercial high-sensitivity cardiac troponin T (hs-cTnT) assays measure both intact and degraded cTnT forms (i.e. total cTnT) and values are often elevated in chronic kidney disease (CKD) patients. Th

S Selma Salonen

Early differentiation between paroxysmal and persistent atrial fibrillation based on interpretable machine learning: a multicenter retrospective study

No abstractBioData Min. 2026 Feb 6. doi: 10.1186/s13040-026-00525-5. Online ahead of print.NO ABSTRACTPMID:41652525 | DOI:10.1186/s13040-026-00525-5

S Sijin Li

Modified cardiometabolic index and the risk of new-onset chronic diseases: a nationwide prospective cohort study

No abstractDiabetol Metab Syndr. 2026 Feb 6. doi: 10.1186/s13098-026-02090-7. Online ahead of print.NO ABSTRACTPMID:41652488 | DOI:10.1186/s13098-026-02090-7

Y Yilin Pan

Identification of glycosylation-related gene signatures associated with coronary artery disease via integrated transcriptomic and machine learning analyses

Eur J Med Res. 2026 Feb 6. doi: 10.1186/s40001-026-04000-z. Online ahead of print.ABSTRACTBACKGROUND: On a global scale, coronary artery disease (CAD) continues to be one of the leading causes of morbidity and death. Glycosylation, a vital post-translational modification, has been linked to a range

K Kangjun Fan

COPD airway epithelial cells-derived extracellular vesicles contribute to endothelial dysfunction and atherosclerosis via the miR-141-3p/PDCD4 axis

J Nanobiotechnology. 2026 Feb 6. doi: 10.1186/s12951-026-04091-0. Online ahead of print.ABSTRACTBACKGROUND: Chronic obstructive pulmonary disease (COPD) frequently coexists with extrapulmonary comorbidities, most notably cardiovascular diseases (CVD). However, the mechanisms linking COPD to CVD, par

Z Zihan Wang

Effects of ablation versus drug therapy on clinical outcomes and quality of life by frailty status in atrial fibrillation: a post hoc analysis of the CABANA trial

BMC Med. 2026 Feb 7. doi: 10.1186/s12916-026-04676-4. Online ahead of print.ABSTRACTBACKGROUND: Frailty is highly prevalent in patients with atrial fibrillation (AF) and is associated with adverse outcomes compared with non-frail individuals. This study aimed to explore whether the effects of ablati

L Lili Wang