Guideline Adherence in Myocardial Infarction Treatment
No abstractJAMA Cardiol. 2025 Dec 17. doi: 10.1001/jamacardio.2025.4569. Online ahead of print.NO ABSTRACTPMID:41405881 | DOI:10.1001/jamacardio.2025.4569
NERP-4-Deleted VGF Impairs β-Cell Granulogenesis and Insulin Secretion
FASEB J. 2025 Dec 31;39(24):e71365. doi: 10.1096/fj.202502474R.ABSTRACTNeuroendocrine regulatory peptide-4 (NERP-4) processed from the granin protein VGF functions as a positive allosteric modulator that acts on the amino acid transporter SNAT2 expressed on pancreatic β cells. NERP-4 promotes insuli
Disparities in cardiometabolic and cardiovascular risk after breast cancer: the pathways heart study
JNCI Cancer Spectr. 2025 Dec 17:pkaf117. doi: 10.1093/jncics/pkaf117. Online ahead of print.ABSTRACTBACKGROUND: Cardiometabolic risk factors (CMRF) and cardiovascular disease (CVD) incidence in racially and ethnically underrepresented women with breast cancer (BC) are not well characterized.METHODS:
Unveiling the neuroprotective power: the role of autophagy in remote ischemic conditioning
Metab Brain Dis. 2025 Dec 17;41(1):4. doi: 10.1007/s11011-025-01765-w.ABSTRACTA stroke is a sudden neurological impairment caused by damage to the vascular system of the central nervous system. Remote ischemic conditioning (RIC) has emerged as a promising therapeutic strategy, gaining attention for
In vitro and in vivo hemocompatibility study of fish swim bladder-derived biomaterials for the application of chronic venous disease
J Mater Sci Mater Med. 2025 Dec 17. doi: 10.1007/s10856-025-06969-1. Online ahead of print.ABSTRACTChronic venous disease (CVD) is a prevalent condition affecting the venous system of the lower limbs, characterized by venous hypertension and regurgitation resulting from congenital or acquired venous
Stage-specific risks of mortality and renal outcomes in cardiovascular-kidney-metabolic syndrome: findings from a nationwide Japanese cohort
Clin Exp Nephrol. 2025 Dec 17. doi: 10.1007/s10157-025-02800-x. Online ahead of print.ABSTRACTBACKGROUND: Cardiovascular-kidney-metabolic (CKM) syndrome, integrating cardiovascular disease (CVD), chronic kidney disease (CKD), and metabolic dysfunction, is a construct proposed by the American heart a
SGLT2 inhibitors and their role in reducing adiposopathy and inflammation in diabetes and non-diabetes CKD patients
Int Urol Nephrol. 2025 Dec 17. doi: 10.1007/s11255-025-04965-6. Online ahead of print.ABSTRACTAIMS: This study aims to evaluate differences in adiposopathy and specific inflammatory biomarkers between type 2 diabetes mellitus (T2DM) and non-T2DM patients across various stages of chronic kidney disea
Impact of arterial occlusion location on early neurological deterioration in patients with minor stroke treated with intravenous thrombolysis. The MINORCAT-END study
Neurol Sci. 2025 Dec 17;47(1):12. doi: 10.1007/s10072-025-08721-7.ABSTRACTPURPOSE: To assess the proportion of early neurological deterioration (END) in patients with minor stroke, its impact on 3-month clinical outcomes, and the influence of large vessel occlusion (LVO) location on END development.
Myrtenal Ameliorates Ischemic Brain Injury Diabetic and Non-Diabetic Rats
Neurochem Res. 2025 Dec 17;51(1):15. doi: 10.1007/s11064-025-04629-y.ABSTRACTIschemic stroke (IS) is a leading cause of death and permanent disability worldwide. Diabetes is a major risk factor for IS and independently increases mortality. This study investigated the neuroprotective effects of Myrte
Revolutionizing type 2 diabetes management: the role of the pharmacist in unlocking the potential of tirzepatide
Saudi Pharm J. 2025 Dec 17;33(6):51. doi: 10.1007/s44446-025-00050-2.ABSTRACTType 2 diabetes mellitus (T2D) affects over 460 million people worldwide and profoundly diminishes their quality of life. Its onset is driven by obesity, sedentary behavior, and genetic predisposition, leading to insulin re
Association between serous macular detachment and choroidal vascular architecture in treatment-Naïve branch retinal vein occlusion
Int Ophthalmol. 2025 Dec 17;46(1):35. doi: 10.1007/s10792-025-03912-9.ABSTRACTPURPOSE: Branch retinal vein occlusion (BRVO) is a common retinal vascular disorder that can cause visual impairment through macular edema and ischemia. The primary aim of this study was to investigate choroidal structural
Nutrition and the Kidney: Beyond Restriction
Rev Med Chil. 2025 Nov;153(11):803-814. doi: 10.4067/s0034-98872025001100803. Epub 2025 Oct 15.ABSTRACTChronic kidney disease is a growing global health concern, driven by aging and comorbidities such as diabetes and hypertension. Proper nutrition is essential to slowing disease progression and redu
Extension and Severity of Coronary Heart Disease Related to Lipoprotein A Levels in Patients Hospitalized in a Cardiac Intensive Care Unit (DIPCOL Registry)
Rev Med Chil. 2025 Nov;153(11):782-792. doi: 10.4067/s0034-98872025001100782. Epub 2025 Oct 15.ABSTRACTLipoprotein (a) [Lp(a)] levels are closely related to the development of ischemic heart disease in international studies; however, the impact on the severity of coronary and cardiac involvement in
Sudden Cardiac Death: Trend Analysis by Sex and Age, Chile 2010 to 2020
Rev Med Chil. 2025 Nov;153(11):760-772. doi: 10.4067/s0034-98872025001100760. Epub 2025 Oct 15.ABSTRACTSudden cardiac death (SCD) is a rare and unexpected event that occurs in apparently healthy individuals. In Chile, only one report has evaluated its incidence, published ten years ago.AIM: To descr
Circular RNAs as Biomarkers and Therapeutic Targets in Diabetic Cardiovascular Complications
Endocrinol Diabetes Metab. 2026 Jan;9(1):e70149. doi: 10.1002/edm2.70149.ABSTRACTBACKGROUND: The global prevalence of diabetes mellitus (DM) is rising rapidly and is projected to reach unprecedented levels by 2035 and 2050, with a disproportionate burden among elderly populations and in low- and mid
Association Between Free Triiodothyronine to Free Thyroxine Ratio and Hemorrhagic Transformation After Intravenous Thrombolysis in Acute Ischemic Stroke Patients
Brain Behav. 2025 Dec;15(12):e71140. doi: 10.1002/brb3.71140.ABSTRACTBACKGROUND: Hemorrhagic transformation (HT) is a critical complication following intravenous thrombolysis (IVT) in acute ischemic stroke (AIS). Emerging evidence indicates thyroid homeostasis' potential role in cerebrovascular outc
Long COVID as Intermediate Physiology: Rethinking Autonomic Dysfunction and Medical Uncertainty
No abstractJ Am Coll Cardiol. 2025 Dec 17:S0735-1097(25)10252-0. doi: 10.1016/j.jacc.2025.10.083. Online ahead of print.NO ABSTRACTPMID:41405529 | DOI:10.1016/j.jacc.2025.10.083
Delayed Diagnosis of Transthyretin Amyloid Cardiomyopathy in the Veterans Health Administration
J Am Coll Cardiol. 2025 Dec 17:S0735-1097(25)09921-8. doi: 10.1016/j.jacc.2025.10.021. Online ahead of print.ABSTRACTBACKGROUND: Timely diagnosis and treatment are critical to reduce morbidity and mortality for patients with transthyretin amyloidosis with cardiomyopathy (ATTR-CM). Limited existing d
Management of Peripheral Artery Disease in Adults With Diabetes: 2025 ACC Scientific Statement: A Report of the American College of Cardiology
J Am Coll Cardiol. 2025 Dec 17:S0735-1097(25)10282-9. doi: 10.1016/j.jacc.2025.11.027. Online ahead of print.ABSTRACTPeripheral artery disease (PAD) is prevalent among people with diabetes, and the combination is associated with high risk of cardiovascular events and adverse limb outcomes. Greater a
Reply: Underestimation of Risk or Overascertainment of Events in Assessing Risk Prediction Equations?
No abstractJ Am Coll Cardiol. 2025 Dec 9:S0735-1097(25)09321-0. doi: 10.1016/j.jacc.2025.09.1510. Online ahead of print.NO ABSTRACTPMID:41405525 | DOI:10.1016/j.jacc.2025.09.1510
What About Love? A Review of Interventions for Patients With Heart Disease and Their Intimate Partners: Recommendations for Cardiac Rehabilitation
Can J Cardiol. 2025 Dec 16:S0828-282X(25)01166-3. doi: 10.1016/j.cjca.2025.09.014. Online ahead of print.ABSTRACTSocial relationships, particularly the quality of intimate partnerships, play a significant role in cardiovascular outcomes and recovery. While most cardiac care focuses on individual pat
Quantitative Coronary Plaque Analysis in Clinical Practice: 2025 ACC Scientific Statement: A Report of the American College of Cardiology
JACC Cardiovasc Imaging. 2025 Dec 17:S1936-878X(25)00654-0. doi: 10.1016/j.jcmg.2025.11.008. Online ahead of print.ABSTRACTTechnological advances in coronary computed tomography angiography and artificial intelligence have resulted in an increasing capability to analyze and quantify information abou
Maternal Renal Function During Pregnancy and the Early Postpartum Period in Normotensive and Hypertensive Pregnancies
J Obstet Gynaecol Res. 2025 Dec;51(12):e70172. doi: 10.1111/jog.70172.ABSTRACTAIM: We aimed to assess renal function trends during pregnancy and the early postpartum period and establish trimester-specific reference ranges for maternal renal function parameters in Japan, including comparisons with p
Analysis of Diagnostic Clues in a Rare Case of Ventricular Preexcitation Masking Occlusive Myocardial Infarction of the Left Anterior Descending Artery
Ann Noninvasive Electrocardiol. 2026 Jan;31(1):e70142. doi: 10.1111/anec.70142.ABSTRACTAcute occlusive myocardial infarction (OMI) complicated by ventricular pre-excitation can present diagnostic challenges. This case describes a 78-year-old male with an 11-h history of chest tightness. A reduction