Targeting bromodomain and extraterminal proteins in cardiovascular disease: Pathological mechanisms and therapeutic applications

J Int Med Res. 2026 Jul;54(7):3000605261465295. doi: 10.1177/03000605261465295. Epub 2026 Jul 9.ABSTRACTBromodomain and extraterminal proteins have emerged as key epigenetic regulators that coordinate transcriptional programs fundamental to cardiovascular physiology and disease. Although bromodomain

K Kaixuan Zhang

Efficacy and Safety of SGLT2 Inhibitors and GLP-1 Receptor Agonists on Ventricular Arrhythmias and Cardiovascular Events: A Disease-Stratified Network Meta-Analysis

Diabetes Obes Metab. 2026 Jul 9. doi: 10.1111/dom.71094. Online ahead of print.ABSTRACTBACKGROUND: The effects of individual sodium-glucose cotransporter-2 inhibitors (SGLT2 inhibitors) and glucagon-like peptide-1 receptor agonists (GLP-1 receptor agonists) on ventricular arrhythmias (VAs) remain un

W Wen-Ting Sun

Environmental Toxicants and Polycystic Ovary Syndrome: Implications for a Metabolic-Ovarian Framework (PMOS) - A Systematic Review

Biol Trace Elem Res. 2026 Jul 9. doi: 10.1007/s12011-026-05218-y. Online ahead of print.ABSTRACTBACKGROUND: Polycystic ovary syndrome (PCOS) is increasingly recognized as a systemic condition characterized by intricate endocrine and metabolic dysregulation. Emerging evidence suggests that environmen

J James O Ibibama

CGM Accuracy in a Fragmented Regulatory Landscape: A Commentary on Harmonisation and Recent Evidence

No abstractDiabetes Obes Metab. 2026 Jul 9. doi: 10.1111/dom.71098. Online ahead of print.NO ABSTRACTPMID:42426430 | DOI:10.1111/dom.71098

T Tadej Battelino

Non-steroidal anti-inflammatory drug use in patients with varying severity of coronary artery disease

Eur J Clin Pharmacol. 2026 Jul 10;82(8):202. doi: 10.1007/s00228-026-04132-5.ABSTRACTPURPOSE: We examined temporal trends in NSAID use among patients referred for evaluation of suspected coronary artery disease (CAD).METHODS: We conducted a drug utilisation study using population-based healthcare da

A Anne Bech-Drewes

Severe hypereosinophilia and eosinophilic myocarditis during secondary plasma cell leukemia: evidence of a paraneoplastic manifestation of aggressive myeloma evolution

Ann Hematol. 2026 Jul 9. doi: 10.1007/s00277-026-07172-0. Online ahead of print.ABSTRACTSecondary plasma cell leukemia (sPCL) represents one of the most aggressive forms of Multiple Myeloma (MM) progression and remains associated with poor outcomes despite the availability of novel immunotherapeutic

M Maria Elisabetta Catini

Automated risk scoring for venous thromboembolism using large language models with expert knowledge-augmented prompting: a multicenter validation study

NPJ Digit Med. 2026 Jul 9. doi: 10.1038/s41746-026-02929-3. Online ahead of print.ABSTRACTVenous thromboembolism (VTE) is a common but preventable complication in hospitalized patients, yet standardized risk scoring using unstructured electronic health records (EHRs) remains challenging. We retrospe

J Jing Ma

Development of a rapid ex vivo tumor platform for drug response prediction in lung cancer

NPJ Precis Oncol. 2026 Jul 9. doi: 10.1038/s41698-026-01598-5. Online ahead of print.ABSTRACTDespite advances in systemic therapies for patients with (locally) advanced stage lung cancer, response rates remain poor, underscoring the urgent need for predictive models to guide therapy selection. Patie

R Rianne D W Vaes

Postpartum perspectives on navigating hypertensive diseases of pregnancy: a qualitative study

Sci Rep. 2026 Jul 9. doi: 10.1038/s41598-026-61473-y. Online ahead of print.ABSTRACTHypertensive disorders of pregnancy (HDP) affect 1 in 7 pregnancies and is on the rise. It is the most prevalent complication during pregnancy and the most severe diagnoses are associated with one-third of maternal d

A Anna Perry

Prevalence and trends of hypertension among South Asian adults: a systematic review and meta-analysis

J Hum Hypertens. 2026 Jul 9. doi: 10.1038/s41371-026-01178-x. Online ahead of print.ABSTRACTHypertension, a major contributor to global cardiovascular disease related deaths, has seen a rise in low- and middle-income countries, especially in South Asia (SA) where ongoing demographic and lifestyle tr

P Priyanga Ranasinghe

Timothy syndrome and CACNA1C-Related Disorder: first international language and management guidelines consensus statement

Eur J Hum Genet. 2026 Jul 9. doi: 10.1038/s41431-026-02178-8. Online ahead of print.ABSTRACTTimothy syndrome is a multisystemic genetic disorder, classically characterised by prolonged QT interval and subsequent cardiac arrhythmias, neurodevelopmental disorders including developmental delay and auti

J Jack F G Underwood

Exploration of the efficacy and multivariate analysis of 5G remote rehabilitation intervention based on peer education model for patients after coronary intervention

Sci Rep. 2026 Jul 9. doi: 10.1038/s41598-026-59972-z. Online ahead of print.ABSTRACTThis study aims to investigate the effects of a peer education-based model utilizing 5G remote rehabilitation guidance with wearable smart devices on patients with coronary heart disease undergoing percutaneous coron

Y Yuping Long

QRS fragmentation and long-term cardiovascular outcomes and mortality: a population-based cohort study

Sci Rep. 2026 Jul 9. doi: 10.1038/s41598-026-57438-w. Online ahead of print.ABSTRACTFragmented QRS (fQRS) on electrocardiography (ECG) has been identified as a possible marker of myocardial conduction abnormalities and adverse cardiovascular events. In this cohort study, we investigated the presence

H Hanieh Gholamalizadeh

Beyond the procedure: a game-theoretic analysis of multilevel determinants shaping doctor-patient engagement after angioplasty

Sci Rep. 2026 Jul 9. doi: 10.1038/s41598-026-59869-x. Online ahead of print.ABSTRACTCardiovascular diseases (CVDs) are a leading global health burden, with coronary artery disease (CAD) often requiring percutaneous coronary intervention (PCI). While PCI improves survival, long-term outcomes hinge on

Z Zahra Khodadadi

Longitudinal trajectories of the TyG-WHtR index and the risk of cardiovascular-metabolic multimorbidity: evidence from the CHARLS prospective cohort

Sci Rep. 2026 Jul 9. doi: 10.1038/s41598-026-57057-5. Online ahead of print.ABSTRACTCardiovascular-metabolic multimorbidity (CMM) has emerged as a defining clinical and public health challenge of ageing societies, characterised by exponential increases in all-cause mortality and healthcare expenditu

X Xing-Yu Zhu

The Cat Gut Microbial Genome Collection reveals global structure of the feline gut microbiome

NPJ Biofilms Microbiomes. 2026 Jul 9. doi: 10.1038/s41522-026-01088-3. Online ahead of print.ABSTRACTThe gut microbiome is a critical determinant of mammalian health, yet our understanding is largely derived from humans and laboratory models. The ecological principles governing the microbiome of glo

Z Zhixin Lei

Maternal cold exposure improves offspring metabolic health via a milk lithocholic acid-microbiota-Th17 axis

NPJ Biofilms Microbiomes. 2026 Jul 9. doi: 10.1038/s41522-026-01092-7. Online ahead of print.ABSTRACTMetabolic diseases are rising with a trend toward earlier onset, yet effective preventive strategies remain limited. While cold exposure improves metabolic health in adults, its role during pregnancy

X Xuejie Han

Atomic Force Microscopy Based Single Molecule Recognition: Deciphering Biological Interactions at the Nanoscale

J Mol Recognit. 2026 Jul;39(4):e70042. doi: 10.1002/jmr.70042.ABSTRACTAtomic Force Microscopy (AFM) based single molecule recognition has emerged as a transformative paradigm in nanoscale biology, enabling direct investigation of biological interactions under physiological conditions. This technolog

H Huaiwei Zhang

Accumulation of multiple uncontrolled risk factors among individuals with type 2 diabetes: a cross-sectional study of a registry-based cohort

Prim Care Diabetes. 2026 Jul 9:S1751-9918(26)00116-6. doi: 10.1016/j.pcd.2026.07.001. Online ahead of print.ABSTRACTAIMS: To assess the prevalence of uncontrolled cardiovascular risk factors (RFs) and missing measurements among adults with type 2 diabetes (T2D) and to identify characteristics associ

S Suchetana De Storvik

Phospholipids as preventive or therapeutic agents for various diseases

Nutrition. 2027 Jan 5:113109. doi: 10.1016/j.nut.2026.113109. Online ahead of print.ABSTRACTPhosphatidylcholine (PC), phosphatidylserine (PS), phosphatidylethanolamine (PE), and sphingomyelin (SM) are four main types of phospholipids in the plasma membrane of mammalian cells. These phospholipids are

J Jeong-Hun Kang

Lung Transplantation for Pulmonary Alveolar Proteinosis - a Retrospective International Multi-Center Analysis

Eur Respir J. 2026 Jul 9:2502351. doi: 10.1183/13993003.02351-2025. Online ahead of print.ABSTRACTBACKGROUND: Pulmonary alveolar proteinosis (PAP) is a rare disease. Only a small number of case reports describing lung transplantation (LTx) as a treatment option for PAP have been published. Due to th

S Stefan Schwarz

Prevalence and burden of coronary artery disease in young adults undergoing clinically indicated coronary CT angiography

Open Heart. 2026 Jul 9;13(2):e004199. doi: 10.1136/openhrt-2026-004199.ABSTRACTBACKGROUND: The reported prevalence and burden of coronary artery disease in young adults varies markedly in published studies from the 1950s through 2000s but has not been evaluated in a large contemporary multicentre co

K Kevin J O'Gorman

AI-enhanced electrocardiography as a digital biomarker platform in cardiovascular medicine: clinical applications, validation gaps and future implementation pathways

Open Heart. 2026 Jul 9;13(2):e004211. doi: 10.1136/openhrt-2026-004211.ABSTRACTArtificial intelligence applied to the ECG is expanding the clinical role of this widely available diagnostic tool beyond conventional waveform interpretation by enabling identification of electrophysiological patterns as

D Damiano Venturiello

Compartment syndrome is associated with acute kidney injury following revascularisation in patients with lower extremity arterial occlusive disease: a retrospective cohort study

Ren Fail. 2026 Dec;48(1):2697560. doi: 10.1080/0886022X.2026.2697560. Epub 2026 Jul 9.ABSTRACTBACKGROUND: Compartment syndrome (CS) is a severe complication after revascularisation for lower extremity arterial occlusive disease (LEAOD), but its association with systemic complications remains unclear

R Renzhong Ding