Circadian Rhythms in Drug Response: From Molecular Clocks to Precision Dosing

Annu Rev Pharmacol Toxicol. 2026 Oct 12. doi: 10.1146/annurev-pharmtox-060325-102258. Online ahead of print.ABSTRACTCircadian rhythms organize mammalian physiology across the 24-h day through molecular clocks coordinated by the central clock in the suprachiasmatic nucleus and distributed to peripher

R Ronan Lordan

The Inverted Sign: Rule-In, Rule-Out, and the Epistemology of the Red Flag

J Eval Clin Pract. 2026 Oct;32(7):e70674. doi: 10.1111/jep.70674.ABSTRACTRATIONALE, AIMS AND OBJECTIVES: A validated rule-out instrument can turn the collective absence of warning findings into an explicit warrant for stopping a specified diagnostic inquiry. This paper characterises that inversion i

A Albert Grüger

Correction to: Infective Endocarditis: Diagnosis, Antibiotic Therapy, and Management: A Scientific Statement From the American Heart Association

No abstractCirculation. 2026 Oct 13;154(15):e620. doi: 10.1161/CIR.0000000000001485. Epub 2026 Oct 12.NO ABSTRACTPMID:42862916 | DOI:10.1161/CIR.0000000000001485

D Daniel C DeSimone

Cardiovascular Complications of Chronic Liver Disease

Circulation. 2026 Oct 13;154(15):1518-1536. doi: 10.1161/CIRCULATIONAHA.126.079443. Epub 2026 Oct 12.ABSTRACTChronic liver disease is an increasingly prevalent and heterogeneous syndrome with important consequences for cardiovascular function. As the global burdens of chronic liver disease and cirrh

S Seong Park

Trends and Distribution of Low-Density Lipoprotein Cholesterol Levels Among US Adults and Adolescents Without Atherosclerotic Cardiovascular Disease, 1999 to 2023

No abstractCirculation. 2026 Oct 13;154(15):1510-1514. doi: 10.1161/CIRCULATIONAHA.126.080677. Epub 2026 Oct 12.NO ABSTRACTPMID:42862907 | DOI:10.1161/CIRCULATIONAHA.126.080677

S Shannon Lyon

Intraoperative hypotension and postoperative acute kidney injury or myocardial injury after liver resection: A protocol for a systematic review and meta-analysis

PLoS One. 2026 Oct 12;21(10):e0357750. doi: 10.1371/journal.pone.0357750. eCollection 2026.ABSTRACTBACKGROUND: Liver resection creates a clinical tension between limiting operative bleeding and maintaining organ perfusion. Low central venous pressure, fluid restriction, vascular inflow occlusion and

Y Yi Duan

Texture-aware diffusion modelling for severity-conditioned synthetic progression-like visualization of diabetic foot ulcers from single images

PLoS One. 2026 Oct 12;21(10):e0359540. doi: 10.1371/journal.pone.0359540. eCollection 2026.ABSTRACTDiabetic foot ulcers (DFUs) are serious complications of diabetes associated with delayed healing, infection, and limb amputation. Modelling DFU progression remains challenging because publicly availab

P Pratham Kaushik

Exploration of treatment burden during transition onto kidney replacement therapy: A longitudinal qualitative study

PLoS One. 2026 Oct 12;21(10):e0360290. doi: 10.1371/journal.pone.0360290. eCollection 2026.ABSTRACTBACKGROUND: People with kidney disease who need to transition onto kidney replacement therapy (KRT) face a life-changing diagnosis. This process involves complex decisions about treatment and a high vo

C Catrin Jones

Knowledge, willingness, and self-efficacy in CPR: A two-phase study of prevalence and preliminary peer-led workshop in a Malaysian tertiary institution

PLoS One. 2026 Oct 12;21(10):e0360510. doi: 10.1371/journal.pone.0360510. eCollection 2026.ABSTRACTBACKGROUND: Out-of-hospital cardiac arrest remains a major public health concern, and early cardiopulmonary resuscitation (CPR) by bystanders is crucial for improving survival outcomes. University stud

S Siew-Keah Lee

A 'First-Time-Right' strategy in secondary prevention of coronary artery disease: Rationale and design of the prospective, temporally controlled observational GOLDEN study

Cardiology. 2026 Oct 12:1. doi: 10.1159/crd/absag017. Online ahead of print.ABSTRACTIntroduction After an acute coronary syndrome (ACS) or coronary revascularisation, the risk of recurrent vascular events remain substantial. Despite clear guideline recommendations, secondary prevention and long-term

M Manon van den Bogaart

Cardiovascular Functional Cell Injury and Cardiovascular Diseases: Mechanistic Insights and Exercise Interventions

Ann N Y Acad Sci. 2026 Oct;1564(1):e70435. doi: 10.1111/nyas.70435.ABSTRACTCardiovascular diseases (CVDs) are a leading cause of mortality worldwide and substantially impair physical health, psychological well-being, and quality of life. Cardiovascular functional cells, including cardiomyocytes, car

S Shaokai Tang

Hemodynamic Characterization of a Circular Shunt After Arterial Switch in a Neonate to Guide Management Strategy

Ann Card Anaesth. 2026 Oct 1;29(4):650-656. doi: 10.4103/aca.aca_29_26. Epub 2026 Oct 12.ABSTRACTA circular shunt is a complex and often critical condition in neonates after cardiac surgery. We report a case of a newborn with refractory hypoxemia and a circular shunt following an arterial switch ope

M Mohan Madan Maddali

A Rare Case of Leptospirosis-Induced Fulminant Myocarditis: A Case Report

Ann Card Anaesth. 2026 Oct 1;29(4):646-649. doi: 10.4103/aca.aca_325_25. Epub 2026 Oct 12.ABSTRACTLeptospirosis is a rare but deadly disease that is often difficult to diagnose. Very often, it is a late presentation, and clinicians have limited time to save the patient's life. The authors hereby pre

N Nakul Mittal

Complex Cardiac Tumor with Concomitant Pericardial Effusion and Hemodynamic Compromise in a Septuagenarian: Case Report of Anesthetic and Surgical Considerations

Ann Card Anaesth. 2026 Oct 1;29(4):642-645. doi: 10.4103/aca.aca_11_26. Epub 2026 Oct 12.ABSTRACTPrimary cardiac tumors are rare, and cardiac lymphomas are particularly uncommon. Their presentation can mimic benign tumors, but perioperative management is highly challenging due to risks of tumor-rela

A Amir Zabida

Emergency Transcatheter Aortic Valve Implantation for Decompensated Aortic Stenosis accompanied by Cardiogenic Shock

Ann Card Anaesth. 2026 Oct 1;29(4):638-641. doi: 10.4103/aca.aca_2_26. Epub 2026 Oct 12.ABSTRACTPatients with severe aortic stenosis (AS) often present acutely with decompensated heart failure, cardiogenic shock or cardiac arrest requiring immediate intervention. Treatment options for these patients

A Ajmer Singh

An Extremely Rare Association of the Giant Right Atrium with Uncorrected Tetralogy of Fallot in an Adolescent Male Patient

Ann Card Anaesth. 2026 Oct 1;29(4):634-637. doi: 10.4103/aca.aca_333_25. Epub 2026 Oct 12.ABSTRACTUncorrected tetralogy of Fallot (TOF) can be associated with widespread abnormalities, but the giant right atrium (RA) is an extremely rare one. The giant RA can cause additional problems causing atrial

A Arupratan Maiti

Bentall Procedure in a Patient with Loeys-Dietz Syndrome: A Case Report

Ann Card Anaesth. 2026 Oct 1;29(4):622-626. doi: 10.4103/aca.aca_317_25. Epub 2026 Oct 12.ABSTRACTLoeys-Dietz syndrome (LDS) is a rare autosomal dominant connective tissue disorder characterized by aggressive aortopathy, craniofacial anomalies and systemic involvement. Rapid aortic root dilatation a

D Dheeraj Arora

Management of Non-cardiac Surgery in an Elderly Patient with Uncorrected Double Inlet Left Ventricle: Utility of the Pulse Contour Analysis-Based Cardiac Output Monitor

Ann Card Anaesth. 2026 Oct 1;29(4):618-621. doi: 10.4103/aca.aca_266_25. Epub 2026 Oct 12.ABSTRACTDouble inlet left ventricle (DILV) is a rare congenital heart disease that usually requires surgical treatment in childhood but can survive to old age untreated under certain conditions. In such patient

J Jun Honda

Emergent Cervical Laminoplasty in a Patient with Chronic Thromboembolic Pulmonary Hypertension

Ann Card Anaesth. 2026 Oct 1;29(4):614-617. doi: 10.4103/aca.aca_274_25. Epub 2026 Oct 12.ABSTRACTPatients with chronic thromboembolic pulmonary hypertension (CTEPH) present with a variable degree of pulmonary hypertension (PH), right ventricular dysfunction, and hypoxia. It is challenging if the pa

A Ahmed K Awad

Anesthetic Challenges in Interarterial Right Coronary Artery Anomaly from the Left Sinus of Valsalva: A Case Report

Ann Card Anaesth. 2026 Oct 1;29(4):605-609. doi: 10.4103/aca.aca_323_25. Epub 2026 Oct 12.ABSTRACTCoronary artery anomalies are rare but clinically significant malformations, particularly when involving an interarterial course, which predisposes to ischemia and sudden cardiac death. We report the ca

I Izabela S Coelho

Comparison of Effectiveness of Caudal Dexmedetomidine vs. Caudal Fentanyl with Bupivacaine during Pediatric Cardiac Surgery with regards to Hemodynamic Fluctuations and Postoperative Pain

Ann Card Anaesth. 2026 Oct 1;29(4):594-599. doi: 10.4103/aca.aca_42_25. Epub 2026 Oct 12.ABSTRACTBACKGROUND: Optimum analgesia, reflecting into attenuation of stress response, is pertinent in pediatric cardiac surgery. Narcotics are still the mainstay in providing analgesia, and they are a common ad

R Roshani Nitin Manwani

Three-Point Bedside Congestion Score (IJV Collapsibility + IVC Collapsibility + Central Venous Pressure) in Elective Mitral Valve Surgery: A Prospective Observational Study

Ann Card Anaesth. 2026 Oct 1;29(4):528-537. doi: 10.4103/aca.aca_138_26. Epub 2026 Oct 12.ABSTRACTBACKGROUND: Systemic venous congestion and right-ventricular (RV) dysfunction are key drivers of postoperative hemodynamic instability, prolonged ventilation, and acute kidney injury (AKI) after mitral

M Manisha Sharma

Correlation between albuminuria and glycated haemoglobin in diabetic patients with an eGFR ≥ 60 mL/min/1.73 m²

Ann Biol Clin (Paris). 2026 Oct 12;84(5):0. doi: 10.1684/abc.2026.2065. Online ahead of print.ABSTRACTDiabetic nephropathy is the leading cause of end-stage chronic kidney disease worldwide. Albuminuria, assessed by the urinary albumin-to-creatinine ratio (ACR), is an independent marker of both rena

H Hamza Boutkhil

Perinatal Factors Associated With Standardized Blood Pressure Percentiles for Children Aged 6 to 12 Years: The BOSHI Study

J Clin Hypertens (Greenwich). 2026 Oct;28(10):e70376. doi: 10.1111/jch.70376.ABSTRACTElevated childhood blood pressure (BP) is associated with adulthood cardiovascular mortality. However, evidence of an association between maternal and perinatal factors and standardized childhood BP percentiles in J

H Hiroki Nobayashi