Phytother Res. 2026 Jan 10. doi: 10.1002/ptr.70176. Online ahead of print.ABSTRACTDue to its high recurrence and metastasis rates, the prognosis of pancreatic cancer (PC) patients is extremely poor. Cancer stem cells (CSCs) are the major source of occurrence and progression of PC, suggesting that ta
Comput Methods Biomech Biomed Engin. 2026 Jan 10:1-18. doi: 10.1080/10255842.2025.2612536. Online ahead of print.ABSTRACTTo mitigate the limitations of Light Gradient Boosting Machine (LightGBM) in processing heterogeneous cardiovascular disease (CVD) data, a Hierarchical Quantum Ensemble Model (HQE
Diabet Med. 2026 Jan 9:e70155. doi: 10.1111/dme.70155. Online ahead of print.ABSTRACTAIMS: Gestational diabetes mellitus (GDM) is a well-established independent risk factor for type 2 diabetes mellitus (T2DM) and cardiovascular disease. As risks emerge within the first decade following childbirth, e
Scand J Occup Ther. 2025 Jan;32(1):2613621. doi: 10.1080/11038128.2026.2613621. Epub 2026 Jan 9.ABSTRACTBACKGROUND: Return to work after stroke is a key goal in rehabilitation for people of working age. However, post-stroke fatigue is a common and complex symptom, and how it affects sustainable retu
Alzheimers Dement. 2025 Dec;21 Suppl 2:e107679. doi: 10.1002/alz70856_107679.ABSTRACTBACKGROUND: The cytochrome P450-soluble epoxide hydrolase (CYP450-sEH) pathway has been implicated in cerebral small vessel disease (cSVD) due to the anti-inflammatory and vasoactive effects of epoxide species produ
Alzheimers Dement. 2025 Dec;21 Suppl 2:e106312. doi: 10.1002/alz70856_106312.ABSTRACTBACKGROUND: Accurate differential diagnosis of dementia types is crucial for guiding therapeutic strategies. Previous studies using magnetic resonance imaging (MRI) for differential diagnosis focused on different pa
J Clin Neurol. 2026 Jan;22(1):6-16. doi: 10.3988/jcn.2025.0629.ABSTRACTIn the central Lewy body diseases (LBDs) Parkinson's disease and dementia with Lewy bodies (DLB), by the time parkinsonism or cognitive dysfunction manifests, substantial central neurodegeneration has already occurred. Biomarkers
Medicine (Baltimore). 2026 Jan 9;105(2):e46986. doi: 10.1097/MD.0000000000046986.ABSTRACTRATIONALE: In computed tomography angiography (CTA), the phenomenon of contrast agent separation (CAS) is one of the key imaging features for diagnosing arterial dissection. This case highlights that the "contra
Medicine (Baltimore). 2026 Jan 9;105(2):e46911. doi: 10.1097/MD.0000000000046911.ABSTRACTRATIONALE: Inferior wall myocardial infarction (MI) complicated by ventricular septal rupture (VSR) is a rare but fatal complication of acute MI. Early surgical intervention is associated with a high mortality r
Medicine (Baltimore). 2026 Jan 9;105(2):e46602. doi: 10.1097/MD.0000000000046602.ABSTRACTThis single-center retrospective cohort study aimed to evaluate the effect of Yiqihuoxue Decoction (YQHXD) as an adjunctive therapy on functional recovery in patients with ischemic cerebrovascular disease (ICVD)
Medicine (Baltimore). 2026 Jan 9;105(2):e46831. doi: 10.1097/MD.0000000000046831.ABSTRACTThe impact of obesity on brain health, spanning cerebrovascular disease, cognition, and neuroanatomy, remains incompletely understood. We conducted 2-sample Mendelian randomization to assess the causal effects o
Medicine (Baltimore). 2026 Jan 9;105(2):e47080. doi: 10.1097/MD.0000000000047080.ABSTRACTRATIONALE: Dilated cardiomyopathy (DCM) is a major cause of chronic heart failure, and some patients continue to deteriorate despite guideline-directed medical therapy. Immunoadsorption (IA), which removes patho
Medicine (Baltimore). 2026 Jan 9;105(2):e47097. doi: 10.1097/MD.0000000000047097.ABSTRACTRATIONALE: Takotsubo cardiomyopathy (TCM), also known as stress-induced cardiomyopathy, is an acute heart condition that mimics acute coronary syndrome and usually affects postmenopausal women. In young patients
Medicine (Baltimore). 2026 Jan 9;105(2):e46825. doi: 10.1097/MD.0000000000046825.ABSTRACTAcute heart failure (AHF) remains associated with high short- and long-term mortality, particularly in patients admitted to the intensive care unit (ICU). Reliable biomarkers for early risk stratification are ur
Medicine (Baltimore). 2026 Jan 9;105(2):e46763. doi: 10.1097/MD.0000000000046763.ABSTRACTAcute myocardial infarction (AMI) remains a major cause of morbidity and mortality globally, with percutaneous coronary intervention (PCI) serving as the primary treatment for revascularization of culprit vessel
Medicine (Baltimore). 2026 Jan 9;105(2):e46451. doi: 10.1097/MD.0000000000046451.ABSTRACTPerioperative hypotension (POH) is frequent in noncardiac surgery and is linked to acute kidney injury (AKI), myocardial injury after noncardiac surgery (MINS), and increased postoperative resource use. Previous
Medicine (Baltimore). 2026 Jan 9;105(2):e46988. doi: 10.1097/MD.0000000000046988.ABSTRACTRATIONALE: Lemierre syndrome (LS) is a rare but life-threatening complication of acute oropharyngeal infections. It is characterized by septic thrombophlebitis of the internal jugular vein and subsequent metasta
Medicine (Baltimore). 2026 Jan 9;105(2):e47040. doi: 10.1097/MD.0000000000047040.ABSTRACTStroke is a global cerebrovascular disease. This study mainly explores the association between red cell distribution width to albumin ratio (RAR) and all-cause mortality in stroke survivors, which is helpful for
Medicine (Baltimore). 2026 Jan 9;105(2):e46091. doi: 10.1097/MD.0000000000046091.ABSTRACTThere is ongoing discussion in the medical community on the effect of metformin in cardiac arrhythmias. Investigating the causal relationship between metformin and arrhythmias was the target of the research. We
Medicine (Baltimore). 2026 Jan 9;105(2):e47111. doi: 10.1097/MD.0000000000047111.ABSTRACTSubarachnoid hemorrhage (SAH) and intracerebral hemorrhage (ICH) are the primary subtypes of hemorrhagic stroke. Obesity and dietary factors may play significant roles in their pathogenesis, yet the genetic caus
Medicine (Baltimore). 2026 Jan 9;105(2):e46340. doi: 10.1097/MD.0000000000046340.ABSTRACTRATIONALE: Noonan syndrome (NS) is a RASopathy most frequently associated with mutations in HRAS, NRAS, KRAS, and RRAS2. The contribution of MRAS variants to NS pathogenesis remains poorly characterized, and inf
Medicine (Baltimore). 2026 Jan 9;105(2):e47075. doi: 10.1097/MD.0000000000047075.ABSTRACTRenal anemia is a common complication in maintenance hemodialysis (MHD) patients, closely linked to higher cardiovascular event risk, reduced quality of life, and poor prognosis. This study explored the correlat
Medicine (Baltimore). 2026 Jan 9;105(2):e46784. doi: 10.1097/MD.0000000000046784.ABSTRACTRATIONALE: In patients with atrial fibrillation (AF) complicated by severe aortic stenosis (AS), atrioventricular node ablation (AVNA) combined with permanent pacemaker implantation is an effective treatment str
Medicine (Baltimore). 2026 Jan 9;105(2):e47033. doi: 10.1097/MD.0000000000047033.ABSTRACTThis study aims to investigate whether the genetically predicted tea consumption of different types is causally associated with the risk of stroke. Four statistical datasets from genome-wide association studies
