Front Physiol. 2026 Aug 18;17:1911464. doi: 10.3389/fphys.2026.1911464. eCollection 2026.ABSTRACTBACKGROUND: In 2023, cardiovascular diseases caused an estimated 19.2 million deaths worldwide, accounting for approximately one-third of all global deaths. Despite this heavy burden, there is limited ev
Int J Surg. 2026 Mar 17;112(6):12806-12817. doi: 10.1097/JS9.0000000000005089. eCollection 2026 Jun.ABSTRACTBACKGROUND: Although vascular aging and insulin resistance (IR) are recognized contributors to cardiovascular disease (CVD) pathophysiology, their independent and joint associations with CVD o
Clin Cardiol. 2026 Sep;49(9):e70453. doi: 10.1002/clc.70453.ABSTRACTBACKGROUND: Longitudinal variability in serum uric acid (SUA) has emerged as a potential predictor of adverse cardiovascular outcomes beyond a single baseline measurement. However, the relationship between temporal changes in SUA an
Ugeskr Laeger. 2026 Aug 24;188(35):V12251058. doi: 10.61409/V12251058.ABSTRACTCoronary artery calcium (CAC) scoring is a widely available method for detecting subclinical atherosclerosis. This review finds CAC scoring strongly predicts future cardiovascular events and may refine risk assessment beyo
J Matern Fetal Neonatal Med. 2026 Dec;39(1):2675763. doi: 10.1080/14767058.2026.2675763. Epub 2026 Sep 2.ABSTRACTOBJECTIVE: This study aimed to investigate the correlations of late-pregnancy homocysteine (Hcy) and lipid profiles with disease severity in hypertensive disorders of pregnancy (HDP) and
APMIS. 2026 Sep;134(9):e70256. doi: 10.1111/apm.70256.ABSTRACTMultiple myeloma (MM) is a hematologic malignancy characterized by uncontrolled malignant plasma cell proliferation. B-cell maturation antigen (BCMA) is an attractive therapeutic target due to its high expression on malignant plasma cells
Kidney Res Clin Pract. 2026 Sep 1. doi: 10.23876/j.krcp.26.272. Online ahead of print.ABSTRACTObesity and type 2 diabetes (T2D) are dominant drivers of chronic kidney disease (CKD) within the cardio-kidney-metabolic (CKM) syndrome. Despite advances with renin-angiotensin system inhibitors and sodium
J Genet Couns. 2026 Oct;35(5):e70285. doi: 10.1002/jgc4.70285.ABSTRACTFamilial hypercholesterolemia (FH) is a common monogenic disorder associated with elevated low-density lipoprotein cholesterol and premature cardiovascular disease. Despite Singapore's high FH prevalence and the launch of the Nati
Rev Med Suisse. 2026 Aug 19;22(971):1286-1290. doi: 10.53738/REVMED.2026.22.971.48905.ABSTRACTManaging out-of-hospital cardiac arrest involves significant challenges, including the decision to discontinue resuscitation efforts, which requires a comprehensive assessment that takes into account the cl
Rev Med Suisse. 2026 Aug 26;22(972):1360-1364. doi: 10.53738/REVMED.2026.22.972.48263.ABSTRACTCardiorespiratory arrest is a clinical situation that any physician may encounter, regardless of specialty. A return of spontaneous circulation (ROSC) represents a critical and unstable phase that requires
Exp Physiol. 2026 Sep 2. doi: 10.1113/EP093381. Online ahead of print.ABSTRACTCerebral blood flow (CBF) often becomes compromised in patients suffering from cardiovascular diseases, increasing the risk of neurodegenerative disease and vascular dementia. There is an urgent need for treatments to addr
Can J Urol. 2026 Aug 21;33(4):923-930. doi: 10.32604/cju.2026.075775.ABSTRACTErectile dysfunction (ED) has evolved from a quality-of-life concern to a recognized marker of systemic vascular disease and an early harbinger of cardiovascular events. The Princeton IV Consensus underscores that men prese
Physiol Rep. 2026 Sep;14(17):e71093. doi: 10.14814/phy2.71093.ABSTRACTInsulin resistance (IR) contributes substantially to cardiovascular disease and type 2 diabetes mellitus, with increasing concern among people living with HIV (PLWH). However, sex-specific factors of IR in sub-Saharan Africa remai
Curr Opin Cardiol. 2026 Sep 2. doi: 10.1097/HCO.0000000000001341. Online ahead of print.ABSTRACTPURPOSE OF REVIEW: Nonobstructive coronary artery disease (NOCA) is now frequently detected by coronary CT angiography (CCTA), but the term compresses biologically distinct patterns into a single anatomic
Curr Opin Cardiol. 2026 Sep 2. doi: 10.1097/HCO.0000000000001343. Online ahead of print.ABSTRACTPURPOSE OF REVIEW: Residual inflammatory risk remains an important driver of recurrent vascular events despite contemporary lipid-lowering and antithrombotic therapies. Low-dose colchicine is the first wi
Clin Appl Thromb Hemost. 2026 Jan-Dec;32:10760296261428819. doi: 10.1177/10760296261428819. Epub 2026 Mar 16.ABSTRACTBackgroundThe clinical relevance of the early coagulation disorder (ECD) score, derived from platelet count, international normalized ratio (INR), and activated partial thromboplastin
Arthritis Rheumatol. 2026 Sep 1. doi: 10.1002/art.70299. Online ahead of print.ABSTRACTOBJECTIVE: To determine whether down-regulation of the transcription factor Fli1 in myeloid cells, previously implicated in profibrotic programming in systemic sclerosis (SSc), promotes cardiac fibrosis and dysfun
J Immunol. 2026 Aug 29;215(9):vkag224. doi: 10.1093/jimmun/vkag224.ABSTRACTHepatic ischemia-reperfusion (I/R) injury triggers release of small extracellular vesicles (sEVs) that can function as systemic conveyors of inflammatory signals. While sEV-mediated immune cell modulation has been studied ext
CNS Neurosci Ther. 2026 Sep;32(9):e71099. doi: 10.1002/cns.71099.ABSTRACTBACKGROUND: Ischemic stroke (IS) is an acute cerebrovascular disease characterized by high morbidity and mortality, with limited current treatment options. Tumor protein p53-inducible nuclear protein 2 (Tp53inp2) is known to be
Chem Biol Drug Des. 2026 Sep;108(3):e70386. doi: 10.1111/cbdd.70386.ABSTRACTEmerging evidence indicates that coagulation-related molecular programs are associated with thrombosis, tumor progression, and molecular dysregulation in gastric cancer (GC). However, thrombosis-associated molecular features
Catheter Cardiovasc Interv. 2026 Sep 1. doi: 10.1002/ccd.70824. Online ahead of print.ABSTRACTThe BATMAN (Balloon-Assisted Translocation of the Mitral Anterior leaflet) technique, a novel approach for modifying the anterior leaflet during transcatheter mitral valve replacement (TMVR), has recently d
HGG Adv. 2026 Sep 1:100668. doi: 10.1016/j.xhgg.2026.100668. Online ahead of print.ABSTRACTCardiac iron homeostasis is essential for myocardial energy metabolism and contractile function, yet the genetic and molecular mechanisms governing iron levels within the heart remain poorly understood. We use
No abstractEur Heart J. 2026 Sep 2:ehag606. doi: 10.1093/eurheartj/ehag606. Online ahead of print.NO ABSTRACTPMID:42681860 | DOI:10.1093/eurheartj/ehag606
Diabetes Obes Metab. 2026 Sep 1. doi: 10.1111/dom.71213. Online ahead of print.ABSTRACTBACKGROUND: Chronic inflammation and insulin resistance (IR) are key drivers of cardiovascular disease (CVD); however, their joint impact on cardiovascular risk remains poorly understood.METHODS: We developed the
