Liver Int. 2026 Feb;46(2):e70485. doi: 10.1111/liv.70485.ABSTRACTBACKGROUND AND AIMS: We investigated the associations between SLD, fibrosis stage, and all-cause and cause-specific mortality, with a focus on SLD subtypes.METHODS: We analysed 486 156 UK Biobank participants. SLD cases were identified
No abstractEndocrine. 2025 Dec 29;91(1):3. doi: 10.1007/s12020-025-04524-0.NO ABSTRACTPMID:41460572 | DOI:10.1007/s12020-025-04524-0
Neurochem Res. 2025 Dec 29;51(1):25. doi: 10.1007/s11064-025-04634-1.ABSTRACTThis study aims to investigate the regulatory role and molecular mechanism of the LINC00968/miR-194-5p axis in secondary neurological injury after intracerebral hemorrhage (ICH). A rat ICH model was established by injecting
FASEB J. 2026 Jan 15;40(1):e71378. doi: 10.1096/fj.202502961RR.ABSTRACTMyocardial ischemia-reperfusion (I/R) injury, a major complication of reperfusion therapies for acute myocardial infarction that exacerbates myocardial necrosis, impairs cardiac function, and worsens patient prognosis. Profound m
Aging Clin Exp Res. 2025 Dec 29;38(1):8. doi: 10.1007/s40520-025-03241-y.ABSTRACTBACKGROUND: Cognitive impairment may hinder effective self-management of cardiovascular disease and lead to worsening cardiovascular risk.AIMS: This study aimed to describe the rate of uncontrolled blood pressure, blood
Curr Hypertens Rep. 2025 Dec 29;28(1):5. doi: 10.1007/s11906-025-01349-0.ABSTRACTPURPOSE OF REVIEW: This article summarizes the clinical effects of incretin therapies. We review data from recent clinical trials, beyond glycemic control and weight reduction.RECENT FINDINGS: Incretin therapies are ass
Curr Atheroscler Rep. 2025 Dec 29;28(1):5. doi: 10.1007/s11883-025-01380-1.ABSTRACTPURPOSE OF REVIEW: Atherosclerotic cardiovascular disease (ASCVD) remains a leading cause of morbidity and mortality worldwide. Although there is increasing recognition of sex differences in ASCVD epidemiology, pathog
Curr Cardiol Rep. 2025 Dec 29;28(1):6. doi: 10.1007/s11886-025-02332-6.ABSTRACTPURPOSE OF REVIEW: The purpose of this review is to provide an updated overview of mesenchymal stem cell (MSC)-based regenerative therapies in atherosclerosis. We aim to explore the mechanisms, recent advancements, and ch
Mol Biol Rep. 2025 Dec 29;53(1):224. doi: 10.1007/s11033-025-11390-6.ABSTRACTSarcopenia is a prevalent and debilitating skeletal muscle disorder in the aging population, characterized by progressive loss of muscle mass, strength, and function. Despite its significant impact on mobility, independence
Cell Mol Life Sci. 2025 Dec 29;83(1):8. doi: 10.1007/s00018-025-05967-4.ABSTRACTBACKGROUND: Ischemia/reperfusion injury (I/RI) impedes the progress of flap and allograft transplantation. Among various strategies to address oxidative stress (OS) and mitochondrial dysfunction associated with I/RI, exo
Mol Biomed. 2025 Dec 29;6(1):152. doi: 10.1186/s43556-025-00385-1.ABSTRACTPoly (ADP-ribose) polymerases (PARPs) are a diverse family of enzymes that regulate genome stability, cell death, and stress responses through ADP-ribosylation. Among them, PARP1, PARP2, and PARP3 are central to cellular DNA r
Aging Clin Exp Res. 2025 Dec 29;38(1):7. doi: 10.1007/s40520-025-03244-9.ABSTRACTOBJECTIVE: This paper aims to assess the clinical effectiveness of an Enhanced Recovery After Surgery (ERAS)-based care bundle in facilitating early rehabilitation in patients with acute ischemic stroke (AIS).METHODS: A
Elife. 2025 Dec 29;13:RP100129. doi: 10.7554/eLife.100129.ABSTRACTHypoxia-ischemia (HI), which disrupts the oxygen supply-demand balance in the brain by impairing blood oxygen supply and the cerebral metabolic rate of oxygen (CMRO2), is a leading cause of neonatal brain injury. However, it is unclea
J Gerontol A Biol Sci Med Sci. 2025 Dec 29:glaf286. doi: 10.1093/gerona/glaf286. Online ahead of print.ABSTRACTBACKGROUND: Age-related declines in gonadal and cognitive function are commonly observed, but their relationship is still not completely understood.METHODS: 615 men and 607 women from the B
No abstractCardiol J. 2025;32(6):714-715. doi: 10.5603/cj.103716.NO ABSTRACTPMID:41460175 | DOI:10.5603/cj.103716
No abstractCardiol J. 2025;32(6):712-713. doi: 10.5603/cj.104599.NO ABSTRACTPMID:41460174 | DOI:10.5603/cj.104599
Indian J Ophthalmol. 2026 Jan 1;74(1):111-116. doi: 10.4103/IJO.IJO_902_25. Epub 2025 Dec 29.ABSTRACTPURPOSE: To describe the clinicopathological characteristics of ophthalmic Rosai-Dorfman disease (RDD).METHODS: A 15-year single-center retrospective case series on ophthalmic RDD.RESULTS: Thirteen c
Chemistry. 2025 Dec 29:e03409. doi: 10.1002/chem.202503409. Online ahead of print.ABSTRACTEliminating reactive oxygen species has emerged as an effective therapeutic strategy for diseases related to oxidative stress, such as inflammation, neurodegenerative diseases, and cardiovascular diseases. Mang
Curr Opin Nephrol Hypertens. 2025 Dec 30. doi: 10.1097/MNH.0000000000001153. Online ahead of print.ABSTRACTPURPOSE OF REVIEW: Optimal blood pressure control is essential for managing chronic kidney disease (CKD), as it can reduce cardiovascular risk and mortality. However, recent updates in major in
Curr Opin Nephrol Hypertens. 2025 Dec 30. doi: 10.1097/MNH.0000000000001152. Online ahead of print.ABSTRACTPURPOSE OF REVIEW: This review focuses on new nonpharmacological and drug therapies for lowering blood pressure, hypertension treatment goals, and strategies to improve hypertension control.REC
Neuroreport. 2026 Feb 4;37(2):45-52. doi: 10.1097/WNR.0000000000002237. Epub 2025 Dec 23.ABSTRACTBACKGROUND: Celastrol, a natural plant-derived compound with potent antioxidant and anti-inflammatory properties, demonstrates neuroprotective effects in various central nervous system disorders, though
Chaos. 2025 Dec 1;35(12):123145. doi: 10.1063/5.0297249.ABSTRACTThe conversion of nicotinamide adenine dinucleotide (NAD+) to its reduced form (NADH) by dehydrogenases is a key step in numerous redox reactions and, consequently, in cellular energy conversion. NADH autofluorescence imaging represents
Drug Metab Rev. 2025 Dec 29:1-14. doi: 10.1080/03602532.2025.2611009. Online ahead of print.ABSTRACTPregnane X receptor (PXR; NR1I2) is a promiscuous ligand-activated nuclear receptor traditionally recognized as a master regulator of xenobiotic detoxification. Beyond xenobiotic detoxification, emerg
Niger J Clin Pract. 2025 Dec 1;28(12):1499-1501. doi: 10.4103/njcp.njcp_179_25. Epub 2025 Dec 29.ABSTRACTA splenic artery pseudoaneurysm is an uncommon complication, but a potentially fatal condition of recurrent pancreatitis or necrotising pancreatitis and is often diagnosed incidentally on abdomin
