Cardiooncology. 2026 May 29. doi: 10.1186/s40959-026-00504-z. Online ahead of print.ABSTRACTBACKGROUND: HER2-targeted therapies significantly improve outcomes in HER2-positive breast cancer but are associated with cancer therapy-related cardiac dysfunction (CTRCD), which may necessitate interruption
Crit Care. 2026 May 29. doi: 10.1186/s13054-026-06106-6. Online ahead of print.ABSTRACTBACKGROUND: Immune checkpoint inhibitors (ICIs) are increasingly used as first-line therapy for various malignancies and are associated with a growing spectrum of immune-related adverse events. While many toxiciti
J Cardiothorac Surg. 2026 May 29. doi: 10.1186/s13019-026-04260-0. Online ahead of print.ABSTRACTBACKGROUND: Dilated cardiomyopathy (DCM), a life-threatening cardiovascular disease, affects more than 0.04% of the general population. However, the key genes associated with DCM are still unknown.METHOD
BMC Cardiovasc Disord. 2026 May 30. doi: 10.1186/s12872-026-06047-6. Online ahead of print.ABSTRACTBACKGROUND: Graves' disease is an autoimmune disorder characterized by hyperthyroidism and is often associated with diffuse goiter, Graves' ophthalmopathy, antithyroid peroxidase antibodies, TSH recept
BMC Nephrol. 2026 May 29. doi: 10.1186/s12882-026-05040-7. Online ahead of print.ABSTRACTBACKGROUND: Cardiorenal metabolic (CRM) disease, is identified by the co-location of multiple disorders including obesity, diabetes, hypertension, cardiovascular disease and chronic kidney disease (CKD). Early i
J Health Popul Nutr. 2026 May 29. doi: 10.1186/s41043-026-01351-5. Online ahead of print.ABSTRACTBACKGROUND: The dietary balance of macronutrients may play a critical role in the development of cardio-metabolic diseases. The carbohydrate-to-protein (CHO/Pr) ratio provides an index of this balance; h
Cardiooncology. 2026 May 29;12(1):71. doi: 10.1186/s40959-026-00481-3.ABSTRACTPURPOSE: Cardiovascular (CV) toxicity is prevalent in cancer survivors due to shared risk factors, direct CV injury from cancer therapy (CT), and development/exacerbation of CV risk factors during treatment. Succinct guida
Biol Sex Differ. 2026 May 29. doi: 10.1186/s13293-026-00932-7. Online ahead of print.ABSTRACTAortic stenosis (AS) presents with distinct sex-related differences in clinical manifestation, pathophysiology, and response to treatment. Women typically present at an older age, with greater frailty, more
Genome Biol. 2026 May 29. doi: 10.1186/s13059-026-04119-6. Online ahead of print.ABSTRACTHematopoietic stem cells (HSCs) transition through different functional states throughout life from emergence and expansion in the fetus, homeostasis maintenance in adulthood, and progressive functional decline
Biomark Res. 2026 May 29. doi: 10.1186/s40364-026-00947-7. Online ahead of print.ABSTRACTCardiac troponin is essential for diagnosing myocardial infarction, yet high-sensitivity assays frequently detect troponin elevations in non-ischemic contexts, complicating clinical decision-making. We investiga
Respir Res. 2026 May 29. doi: 10.1186/s12931-026-03750-y. Online ahead of print.ABSTRACTRheumatoid arthritis-associated interstitial lung disease (RA-ILD) is a major extra-articular manifestation of rheumatoid arthritis and a key determinant of patient outcomes. Among its radiologic subtypes, the us
J Med Case Rep. 2026 May 29. doi: 10.1186/s13256-026-06045-4. Online ahead of print.ABSTRACTBACKGROUND: Antihypertensive therapy plays a crucial role in managing cardiovascular disease but may sometimes cause significant hypotension during mobilization, hindering the recovery of activities of daily
BMC Cardiovasc Disord. 2026 May 30. doi: 10.1186/s12872-026-05910-w. Online ahead of print.ABSTRACTOBJECTIVE: This study explored the incidence and risk factors of acute kidney injury (AKI) in patients with hypertrophic obstructive cardiomyopathy (HOCM) undergoing modified Morrow septal myectomy and
BMC Immunol. 2026 May 29. doi: 10.1186/s12865-026-00843-7. Online ahead of print.ABSTRACTOBJECTIVE: The aim of the present work was to investigate the correlation between positive Alzheimer's disease (AD) plasma biological markers and plasma immune cell content as well as clinical characteristics in
Mol Biomed. 2026 May 30;7(1):80. doi: 10.1186/s43556-026-00486-5.ABSTRACTMetabolic dysfunction-associated steatotic liver disease (MASLD), the recently introduced terminology superseding non-alcoholic fatty liver disease (NAFLD), has emerged as the most prevalent chronic liver condition globally. Th
Int Microbiol. 2026 May 30. doi: 10.1007/s10123-026-00845-w. Online ahead of print.ABSTRACTAlthough hypertriglyceridemia (HTG) is a significant contributor to lipid-associated pathologies such as atherosclerotic cardiovascular disease, its regulation by host‒microbiome interactions remain insufficie
NPJ Precis Oncol. 2026 May 30. doi: 10.1038/s41698-026-01518-7. Online ahead of print.ABSTRACTColorectal cancer is a malignant disease with high morbidity and mortality. In recent years, immune checkpoint inhibitors have emerged as a promising therapeutic strategy; however, patients with proficient
Sci Rep. 2026 May 29. doi: 10.1038/s41598-026-55283-5. Online ahead of print.ABSTRACTChildren with congenital heart disease (CHD) are at increased risk of altered early brain development and neurodevelopmental impairments. Although environmental factors are known to influence neurodevelopmental outc
Nat Rev Rheumatol. 2026 May 29. doi: 10.1038/s41584-026-01386-2. Online ahead of print.ABSTRACTRheumatoid arthritis (RA) is associated with a wide spectrum of comorbidities that substantially influence quality of life and long-term outcomes. These include extra-articular manifestations, cardiovascul
NPJ Aging. 2026 May 29. doi: 10.1038/s41514-026-00409-2. Online ahead of print.ABSTRACTPsychotic disorders, including schizophrenia and affective psychosis, affect ~3% of the population and typically emerge in early adulthood. Cardiometabolic disease accounts for much of the 20-year life-expectancy
Biofactors. 2026 May-Jun;52(3):e70122. doi: 10.1002/biof.70122.ABSTRACTMajor depressive disorder (MDD) is a highly disabling psychiatric illness characterized by persistent low mood and psychomotor retardation, often leading to cognitive impairment or even suicidality. As the pathogenesis remains po
J Clin Lipidol. 2026 May 12:S1933-2874(26)00142-X. doi: 10.1016/j.jacl.2026.05.004. Online ahead of print.ABSTRACTOne in 10 individuals 65 years and older has dementia. The most common form is Alzheimer's disease, followed by vascular dementia. There are myriad shared risk factors between brain heal
Nutr Metab Cardiovasc Dis. 2026 Apr 30:104777. doi: 10.1016/j.numecd.2026.104777. Online ahead of print.ABSTRACTAIMS: This viewpoint discusses the current role of bempedoic acid in clinical practice.DATA SYNTHESIS: Randomized clinical trials have shown bempedoic acid efficacy in both reducing LDL-C
Nutr Metab Cardiovasc Dis. 2026 May 5:104778. doi: 10.1016/j.numecd.2026.104778. Online ahead of print.ABSTRACTBACKGROUND AND AIM: There is a rising prevalence of cardiovascular disease (CVD) and CVD-related deaths in Nigeria, and a pressing need for targeted prevention strategies. However, robust e
