Cardiac magnetic resonance imaging in coronary heart disease: IQWiG Reports - Commission No. D24-02

Cologne (Germany): Institute for Quality and Efficiency in Health Care (IQWiG); 2026 Feb 22.ABSTRACTRESEARCH QUESTION: The aim of this report is toassess the benefit of diagnostics using cardiac magnetic resonance imaging as part of a diagnostic strategy, compared with a diagnostic strategy without

I Institute for Quality and Efficiency in Health Care (IQWiG)

Complex role of thrombospondin-1 in aortic aneurysm

No abstractCardiovasc Res. 2026 Feb 14;121(18):2827-2829. doi: 10.1093/cvr/cvaf274.NO ABSTRACTPMID:41689431 | DOI:10.1093/cvr/cvaf274

J Jonathan Golledge

Identification of ALDH1A2-mediated cardioprotective benefits in myocardial ischaemia-reperfusion injury

Cardiovasc Res. 2026 Feb 14;121(18):2922-2938. doi: 10.1093/cvr/cvaf267.ABSTRACTAIMS: Myocardial ischaemia-reperfusion (MIR) injury is one of the major causes of poor prognosis after revascularization in myocardial infarction. Retinoic acid (RA) signalling is activated after myocardial infarction an

W Wei Li

Qualitative analysis of out-of-hospital self-management capabilities and ongoing care needs in patients with gynecological malignancies and venous thromboembolism

Ann Med. 2026 Dec;58(1):2628359. doi: 10.1080/07853890.2026.2628359. Epub 2026 Feb 14.ABSTRACTBACKGROUND: Postoperative patients with gynecological malignant tumors are prone to venous thromboembolism (VTE) due to hypercoagulability and limited mobility, and lack of professional guidance after disch

T Tian-Hua Li

Associations of Arterial Blood Pressure With Radiographic Knee Osteoarthritis and Pain Sensitivity in Middle-Aged and Older Adults

Eur J Pain. 2026 Feb;30(2):e70234. doi: 10.1002/ejp.70234.ABSTRACTOBJECTIVE: High blood pressure (BP) often co-occurs with osteoarthritis (OA) and may influence pain sensitivity, potentially contributing to pain-pathology discordance. We hypothesized that higher BP would associate with reduced pain

C Carlos J Cruz

Uncommon Associations in Duchenne Muscular Dystrophy: Coexistence of Patent Foramen Ovale and Ocular Anomalies

J Coll Physicians Surg Pak. 2026 Feb;36(2):287-288. doi: 10.29271/jcpsp.2026.02.287.ABSTRACTNull.PMID:41689339 | DOI:10.29271/jcpsp.2026.02.287

X Xiaojing Li

Conventional vs. Laser Haemorrhoidectomy for Symptomatic Haemorrhoids: A Meta-Analysis

J Coll Physicians Surg Pak. 2026 Feb;36(2):233-239. doi: 10.29271/jcpsp.2026.02.233.ABSTRACTThis meta-analysis aimed to compare the efficacy and safety of Diode laser haemorrhoidoplasty (DLH) with conventional haemorrhoidectomy (CH) techniques, namely Milligan-Morgan haemorrhoidectomy (MMH) and Ferg

C Chaoyang Wang

Methylene Blue Rescue Therapy for Vasoplegic Shock After Antihypertensive Drug Overdose

Am J Case Rep. 2026 Feb 14;27:e951026. doi: 10.12659/AJCR.951026.ABSTRACTBACKGROUND ß-blocker and calcium channel blocker overdose typically manifests with bradycardia and hypotension. Progression to refractory shock may occur in cases of severe toxicity, requiring vasopressor support. Methylene blu

Y Yousef H I Aqel

Eicosapentaenoic and Docosahexaenoic Acid Levels in Mouse Tissues After Intake of Echium and Ahiflower Oils Rich in Stearidonic and α-Linolenic Acids

Lipids. 2026 Feb 13. doi: 10.1002/lipd.70041. Online ahead of print.ABSTRACTOmega-3 fatty acids (n-3 FA), particularly eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), have been consumed aiming to reduce cardiovascular disease. Fish oil is the main dietary source of EPA and DHA but has li

L Letícia V Segre

Effects of communication disorder status on risk for eleven common health conditions in the All of Us Research Program in the USA: a cross-sectional study

BMJ Open. 2026 Feb 12;16(2):e103384. doi: 10.1136/bmjopen-2025-103384.ABSTRACTOBJECTIVE: To determine if communication disorders (1) increase the risk for common mental and physical health conditions and (2) if risk varies by age of onset (≤25 years (developmental) or >25 years (acquired)) by using

H Hope S Lancaster

Association of symptoms at heart failure diagnosis with hospitalisation and mortality at 6 and 12 months: a retrospective cohort study using UK primary care health records

BMJ Open. 2026 Feb 12;16(2):e107490. doi: 10.1136/bmjopen-2025-107490.ABSTRACTBACKGROUND: We investigated symptoms reported before and after heart failure (HF) diagnosis and their associations with 3-month hospitalisation and mortality.OBJECTIVES: To examine associations between symptoms recorded in

M Mohammad Rizwan Ali

Assessment of health-related quality of life and treatment satisfaction and their associated factors among older adults with heart failure: a prospective observational study in selected hospitals in Northwest Ethiopia

BMJ Open. 2026 Feb 12;16(2):e103989. doi: 10.1136/bmjopen-2025-103989.ABSTRACTOBJECTIVES: To assess health-related quality of life (HRQoL), treatment satisfaction and associated factors among older adults with acute heart failure in Northwest Ethiopia.DESIGN: Prospective, multicentre observational s

G Getachew Yitayew Tarekegn

Linking everyday physical activity and capacity tests using wearable and mobile technologies in older adults and cardiac cohorts: protocol for a pilot observational study

BMJ Open. 2026 Feb 12;16(2):e112539. doi: 10.1136/bmjopen-2025-112539.ABSTRACTINTRODUCTION: This study investigates the potential of digital health technologies (DHTs), such as wearable devices and smartphones, to complement traditional submaximal functional capacity tests, such as the 6 min walk te

S Sara Caramaschi

Personalized Hemodynamic Analysis Based on Multimodal Medical Data and a Cardiovascular Heat Transfer Model

Int J Numer Method Biomed Eng. 2026 Feb;42(2):e70149. doi: 10.1002/cnm.70149.ABSTRACTNon-invasive measurement of basic physiological parameters, such as blood flow and temperature, has long been crucial for daily healthcare and the early screening of cardiovascular diseases. This study aims to integ

Y Yongtao Liu

Pachymic Acid Targets PI3K/Akt Signaling Pathway to Attenuate tPA-Induced Hemorrhagic Transformation After Ischemic Stroke

CNS Neurosci Ther. 2026 Feb;32(2):e70782. doi: 10.1002/cns.70782.ABSTRACTBACKGROUND: Tissue plasminogen activator (tPA)-induced cerebral hemorrhagic transformation (HT) after ischemic stroke limits its clinical use widely. Pachymic acid, a main active component of Poria cocos, mitigates brain ischem

Y Yongshi Wu

KCC2 Dysfunction Mediated by Microglial BDNF/TrkB Signaling Exacerbates Early Post-Stroke Seizure Susceptibility

CNS Neurosci Ther. 2026 Feb;32(2):e70795. doi: 10.1002/cns.70795.ABSTRACTBACKGROUND: Post-stroke seizures are a common and debilitating complication with limited therapeutic options, underscoring the need to identify novel molecular targets. Disruption of chloride homeostasis via impaired potassium

J Jing Zhou

Socio-demographic and economic factors associated with unhealthy food consumption among women of reproductive age in Tanzania: a nationwide cross-sectional study

J Health Popul Nutr. 2026 Feb 13. doi: 10.1186/s41043-026-01260-7. Online ahead of print.ABSTRACTINTRODUCTION: The rising consumption of unhealthy foods, characterized by high levels of sugar, salt, and unhealthy fats, poses significant health risks to women. Urbanization and globalization have shif

J Jovinary Adam

Human umbilical mesenchymal stem cell-derived mitochondria transplantation suppresses sFLT-1 secretion by regulating calcineurin-NFAT-dependent pathways in angiotensin II-induced preeclampsia rats

Stem Cell Res Ther. 2026 Feb 13. doi: 10.1186/s13287-026-04930-9. Online ahead of print.ABSTRACTBACKGROUND: Mitochondrial transplantation (Mito-T) is a novel therapeutic strategy for ischaemic cardiovascular diseases. This study aimed to test the efficacy of human umbilical mesenchymal stem cell-der

H Hui Xing Cui

uPAR deficiency triggers TGFβ1-mediated fibrotic remodeling in a cardiac perivascular-like microenvironment

Stem Cell Res Ther. 2026 Feb 13. doi: 10.1186/s13287-026-04923-8. Online ahead of print.ABSTRACTBACKGROUND: Cardiac fibrosis represents a significant health burden, with endothelial dysfunction and damaged perivascular microenvironment increasingly recognized as key contributors to fibrotic remodeli

Y Yulia Goltseva

Fatal delayed superior mesenteric artery thrombosis after frozen elephant trunk repair in acute type a aortic dissection with false lumen perfusion: a case report

J Cardiothorac Surg. 2026 Feb 13. doi: 10.1186/s13019-025-03812-0. Online ahead of print.ABSTRACTBACKGROUND: Frozen elephant trunk (FET) implantation is an established technique for acute Type A aortic dissection (ATAAD), promoting true lumen expansion and aortic remodeling. However, in patients wit

H Huai-Yu Zhao

Optimising Prescription of Treatment In older patients with Mild hypertension at Increased risk of Serious adverse Events (OPTIMISE2): protocol for a primary care based, open-label, randomised controlled non-inferiority trial

Trials. 2026 Feb 14. doi: 10.1186/s13063-026-09508-7. Online ahead of print.ABSTRACTBACKGROUND: Antihypertensive treatment is effective at reducing the risk of cardiovascular disease, but is associated with adverse events, particularly in older patients with frailty. As a result, deprescribing antih

M Melanie Carr

An antioxidant and injectable hydrogel dressing for repairing MRSA biofilm-infected diabetic wounds

J Nanobiotechnology. 2026 Feb 13. doi: 10.1186/s12951-026-04093-y. Online ahead of print.ABSTRACTChronic non-healing wounds represent a severe complication of diabetes mellitus, which frequently progress to infection, limb amputation, and even mortality. The dysregulated wound microenvironment, mark

Z Zhongwu Bei

Vitamin D and vitamin D receptor polymorphisms modify cardiovascular outcomes in asthma: a prospective cohort study based on the UK Biobank

No abstractBMC Pulm Med. 2026 Feb 13. doi: 10.1186/s12890-026-04167-5. Online ahead of print.NO ABSTRACTPMID:41688998 | DOI:10.1186/s12890-026-04167-5

Z Ziwei Zhang

Stress hyperglycemia ratio in coronary artery disease: a systematic review and meta-analysis of severity and prognosis

Cardiovasc Diabetol. 2026 Feb 14. doi: 10.1186/s12933-026-03100-8. Online ahead of print.ABSTRACTBACKGROUND: The stress hyperglycemia ratio (SHR), calculated as the ratio of admission blood glucose to estimated average glucose derived from glycated hemoglobin, quantifies the degree of relative hyper

C Cui Wang