Hypertensive Hemodynamics in Type II Endoleak: Unveiling Biomechanical Pathways to Thrombosis Impediment and Aneurysm Destabilization via FSI Simulation

Int J Numer Method Biomed Eng. 2026 Mar;42(3):e70150. doi: 10.1002/cnm.70150.ABSTRACTHypertension is a key risk factor for type II endoleaks after endovascular aneurysm repair (EVAR), but the biomechanical mechanisms linking blood pressure to outcomes are unclear. This study aimed to elucidate these

X Xiao Mo

Targeting the NLRP3 Inflammasome in Atherosclerosis: Advances in Anti-Inflammatory Therapies With Bioactive Natural Products

Phytother Res. 2026 Feb 27. doi: 10.1002/ptr.70260. Online ahead of print.ABSTRACTAtherosclerosis (AS) serves as the shared pathological substrate for cardiovascular and cerebrovascular diseases. The traditional passive-accumulation model centered on cholesterol no longer explains why lipid targets

H Haizhen Guo

Unravelling genetic susceptibility and causal factors in liver health using MRI quantification of inflammation, fat and iron in the liver

No abstractHum Genomics. 2026 Feb 28. doi: 10.1186/s40246-026-00913-2. Online ahead of print.NO ABSTRACTPMID:41761370 | DOI:10.1186/s40246-026-00913-2

D Devendra Meena

What constitutes risk in implementation research? Perspectives from a qualitative key-informant study

Implement Sci Commun. 2026 Feb 27. doi: 10.1186/s43058-026-00885-3. Online ahead of print.ABSTRACTBACKGROUND: As implementation research increasingly occurs within routine care settings, determining what constitutes minimal risk is critical to ensuring that ethical oversight is appropriate and propo

E Emmanuel K Tetteh

Hypomethylation of VTRNA2-1 promoter predicts adverse outcomes in peripheral artery disease

Clin Epigenetics. 2026 Feb 27. doi: 10.1186/s13148-026-02087-z. Online ahead of print.ABSTRACTBACKGROUND: Peripheral artery disease (PAD) is a progressive vascular condition with high risks of limb amputation and adverse clinical outcomes. Despite advancements in revascularization techniques, risk s

M Ming-Lung Tsai

Comparative efficacy of tirzepatide and glucagon-like peptide-1 receptor agonists on cardiovascular outcomes in patients with type 2 diabetes: a systematic review and network meta-analysis

Cardiovasc Diabetol. 2026 Feb 27. doi: 10.1186/s12933-026-03113-3. Online ahead of print.ABSTRACTBACKGROUND: Glucagon-like peptide-1 receptor agonists (GLP-1RAs) are widely used therapies for cardiovascular risk reduction in type 2 diabetes (T2D). With the emergence of the SURPASS-CVOT trial, tirzep

A Arveen Shokravi

Anticholinergic drug burden and incident cardiovascular events: a population-based study

BMC Med. 2026 Feb 28. doi: 10.1186/s12916-026-04751-w. Online ahead of print.ABSTRACTBACKGROUND: Drugs with anticholinergic properties are commonly used in older adults for various medical conditions, but the long-term cardiovascular consequences of cumulative exposure have not been well established

N Nanbo Zhu

Circulating protein biomarkers of physical fitness associated with cardiometabolic risk in women after gestational diabetes: a PONCH study

No abstractCardiovasc Diabetol. 2026 Feb 27. doi: 10.1186/s12933-026-03120-4. Online ahead of print.NO ABSTRACTPMID:41761218 | DOI:10.1186/s12933-026-03120-4

E Emilia Kristiansson

Fisetin-loaded nanoparticles as a novel approach for cholesterol regulation in hypercholesterolemia: targeting the ASGR1-mediated mTORC1/AMPK pathway

J Nanobiotechnology. 2026 Feb 27. doi: 10.1186/s12951-026-04181-z. Online ahead of print.ABSTRACTHypercholesterolemia is a major risk factor for the development of atherosclerotic cardiovascular disease. The flavonoid fisetin shows potential cholesterol-regulating effects. Nevertheless, poor solubil

Z Ziyang Zhang

Sensitive periods of BMI change from childhood to adulthood on subclinical cardiovascular outcomes: a 36-year prospective cohort study

BMC Med. 2026 Feb 27. doi: 10.1186/s12916-026-04742-x. Online ahead of print.ABSTRACTBACKGROUND: The sensitive period during which the adult cardiovascular system is particularly vulnerable to body mass index (BMI) changes remains unclear. This study aimed to examine how rates of BMI change from chi

H Hui Yang

Association of pre-transplant pulmonary hypertension and post-transplant major adverse cardiovascular events in kidney transplant recipients: a retrospective study

BMC Nephrol. 2026 Feb 27. doi: 10.1186/s12882-026-04832-1. Online ahead of print.ABSTRACTBACKGROUND: Pulmonary hypertension (PH) frequently complicates end-stage kidney disease, contributing significantly to cardiovascular morbidity and mortality. Some of the pathophysiologic effects of PH may persi

Y Yanqing Lyu

Predicting polyvascular disease with optical coherence tomography angiography and/or optical coherence tomography

No abstractBMC Cardiovasc Disord. 2026 Feb 27. doi: 10.1186/s12872-026-05650-x. Online ahead of print.NO ABSTRACTPMID:41761095 | DOI:10.1186/s12872-026-05650-x

M Minghao Liu

Feasibility and safety of right heart catheterization via median cubital vein in patients with pulmonary hypertension

No abstractBMC Cardiovasc Disord. 2026 Feb 27. doi: 10.1186/s12872-026-05604-3. Online ahead of print.NO ABSTRACTPMID:41761094 | DOI:10.1186/s12872-026-05604-3

Y Yuxing Lai

A blood-based metabolomics study of cardiovascular diseases in Swedish twins reveals apolipoprotein B biology as important for myocardial infarction

Geroscience. 2026 Feb 27. doi: 10.1007/s11357-026-02166-2. Online ahead of print.ABSTRACTCardiovascular diseases are the leading cause of death globally. Consequently, metabolomics studies have in recent years aimed at identifying relevant biomarkers, yet no studies have been performed in twin popul

A Asmus C Skovgaard

Gestational diabetes and life course cardiometabolic health in an American Indian cohort: The Strong Heart Study

No abstractJ Racial Ethn Health Disparities. 2026 Feb 27. doi: 10.1007/s40615-026-02902-6. Online ahead of print.NO ABSTRACTPMID:41760975 | DOI:10.1007/s40615-026-02902-6

E E W Harville

Role of Innate Immune Receptors in Cardiac Damage Linked to Metabolic Disorders

Handb Exp Pharmacol. 2026 Feb 28. doi: 10.1007/164_2026_793. Online ahead of print.ABSTRACTThis chapter underscores the pivotal role of immune receptors, particularly Toll-like receptors (TLRs) and NOD-like receptors (NLRs), in the intricate interplay between metabolic diseases and their associated

A Almudena Val-Blasco

A scalable framework for evaluating health language models

NPJ Digit Med. 2026 Feb 27. doi: 10.1038/s41746-026-02492-x. Online ahead of print.ABSTRACTLarge language models (LLMs) have emerged as powerful tools for analyzing and interpreting complex datasets. Recent studies demonstrate their potential to generate useful, personalized responses when provided

N Neil Mallinar

Cardiovascular endpoints in relation to the central arterial pressure-time indexes

Hypertens Res. 2026 Feb 27. doi: 10.1038/s41440-026-02555-2. Online ahead of print.ABSTRACTMultiple articles focused on the central arterial systolic (SPTI) and diastolic (DPTI) pressure-time indexes and the subendocardial viability ratio (SEVR). However, whether these indexes contribute to risk str

Q Qi-Fang Huang

Response to Correspondence: From single risks to causal pathways: future directions for early cardiovascular biomarker research

No abstractHypertens Res. 2026 Feb 27. doi: 10.1038/s41440-026-02597-6. Online ahead of print.NO ABSTRACTPMID:41760899 | DOI:10.1038/s41440-026-02597-6

A Adriaan Jacobs

A comprehensive nationwide registry study of noncommunicable disease comorbidities and death in cancer patients in Norway-the NCDNOR project

Sci Rep. 2026 Feb 28. doi: 10.1038/s41598-026-41831-6. Online ahead of print.ABSTRACTNoncommunicable disease (NCD) comorbidities are common in cancer patients due to shared risk factors, but few studies have mapped their occurrence across cancer types using detailed national data. In this nationwide

S Simon Lergenmuller

Molecular evolution of animal aging

EMBO J. 2026 Feb 27. doi: 10.1038/s44318-026-00725-z. Online ahead of print.ABSTRACTComparative biology plays a crucial role in uncovering fundamental biological mechanisms and providing evolutionary models for their variation. This approach is particularly valuable for studying aging, given the rem

D Daniel H Nussey

Understanding atrial failure: from diagnosis to clinical implications

Nat Rev Cardiol. 2026 Feb 27. doi: 10.1038/s41569-026-01266-y. Online ahead of print.ABSTRACTAtrial failure is an emerging clinical syndrome that results from an underlying atrial cardiomyopathy and is characterized by impaired atrial haemodynamic and/or electrical function that is sufficient to cau

B Bryce Alexander

Associations between pulse pressure amplification and inflammation in young adults according to body composition: The African-PREDICT study

J Hum Hypertens. 2026 Feb 27. doi: 10.1038/s41371-026-01126-9. Online ahead of print.ABSTRACTPulse pressure amplification (PPA) is a measure of arterial function and wave reflection dynamics. The potential contribution of low-grade systemic inflammation to PPA-particularly in the context of overweig

Y Yolandi Breet

Genome-wide analysis of cardiac ventricular phenotypes reveals novel loci and therapeutic targets for heart failure

Nat Commun. 2026 Feb 27. doi: 10.1038/s41467-026-69982-0. Online ahead of print.ABSTRACTLeft and right ventricular imaging measures are essential for heart failure diagnosis and prognostication, yet their genetic architecture remains underexplored. We conduct genome-wide association analyses of twen

H Hannah L Nicholls