Exp Dermatol. 2026 Jan;35(1):e70210. doi: 10.1111/exd.70210.ABSTRACTPsoriasis, a prevalent chronic inflammatory skin disease, substantially impairs patients' quality of life and is frequently linked to numerous systemic comorbidities. We aimed to investigate whether phenotypic age acceleration (Phen
Clin Epigenetics. 2026 Jan 16. doi: 10.1186/s13148-025-02045-1. Online ahead of print.ABSTRACTHuman Immunodeficiency Virus (HIV) remains a major health challenge despite dramatic advances in treatment and prevention. People living with HIV (PLWH) continue to experience high rates of non-AIDS comorbi
Immunol Rev. 2026 Jan;337(1):e70084. doi: 10.1111/imr.70084.ABSTRACTAging is the most important yet unmodifiable risk factor for cardiovascular disease (CVD). As a result, targeting cardiovascular aging has emerged as a promising strategy to promote long-term cardiovascular health. This review summa
Immunol Rev. 2026 Jan;337(1):e70094. doi: 10.1111/imr.70094.ABSTRACTInflammation is increasingly recognized as a central driver of heart failure (HF), particularly in older adults, yet the underlying immune mechanisms remain diverse and incompletely understood. Clonal hematopoiesis (CH), defined by
Trials. 2026 Jan 16. doi: 10.1186/s13063-026-09426-8. Online ahead of print.ABSTRACTBACKGROUND AND AIMS: About half of the patients with acute ischaemic stroke treated with endovascular thrombectomy (EVT) remains dependent or dies in the first 90 days. Ghrelin is a naturally occurring hormone and mi
No abstractBMC Public Health. 2026 Jan 16. doi: 10.1186/s12889-025-26145-y. Online ahead of print.NO ABSTRACTPMID:41545951 | DOI:10.1186/s12889-025-26145-y
Eur J Med Res. 2026 Jan 17. doi: 10.1186/s40001-026-03838-7. Online ahead of print.ABSTRACTCrohn's disease (CD) is a chronic inflammatory bowel disease with a complex etiology involving genetic, immune, microbial, and environmental factors. Despite advances in understanding its pathogenesis, accurat
Eur J Med Res. 2026 Jan 17. doi: 10.1186/s40001-025-03763-1. Online ahead of print.ABSTRACTBACKGROUND: Accurate individual risk assessment is crucial for guiding and improving the prevention of atherosclerotic cardiovascular disease (ASCVD). Existing prediction models are primarily derived from West
Clin Rheumatol. 2026 Jan 16. doi: 10.1007/s10067-026-07942-1. Online ahead of print.ABSTRACTOBJECTIVES: Both mental health conditions, such as depression, anxiety, and post-traumatic stress disorder (PTSD), and cardiovascular disease (CVD) events are increased in patients with rheumatoid arthritis (
Neurosurg Rev. 2026 Jan 17;49(1):131. doi: 10.1007/s10143-025-04038-3.ABSTRACTTo compare the postoperative incidence rate of seizure, stroke, hemorrhage, and cerebral hyperperfusion syndrome (CHP) in patients undergoing revascularization for Moyamoya disease (MMD) across direct, indirect, or combine
Commun Med (Lond). 2026 Jan 16. doi: 10.1038/s43856-025-01331-6. Online ahead of print.ABSTRACTBACKGROUND: Cardiovascular disease screening faces significant challenges in resource-limited settings, where infrastructure and computational constraints preclude advanced assessment. These constraints ar
Sci Rep. 2026 Jan 16. doi: 10.1038/s41598-026-36292-w. Online ahead of print.ABSTRACTAdults with type 1 diabetes (T1D) are at increased risk of premature atherosclerosis. Sudomotor dysfunction (SMD), an early manifestation of diabetic neuropathy, may contribute to vascular injury. This cross-section
NPJ Digit Med. 2026 Jan 16. doi: 10.1038/s41746-025-02335-1. Online ahead of print.ABSTRACTSouth Asians experience disproportionately elevated cardiometabolic disease risk yet remain underrepresented in genomic research. The OurHealth Study builds a digital biobank of US South Asian adults, integrat
No abstractReprod Sci. 2026 Jan 16. doi: 10.1007/s43032-025-02026-y. Online ahead of print.NO ABSTRACTPMID:41545617 | DOI:10.1007/s43032-025-02026-y
Nat Med. 2026 Jan 16. doi: 10.1038/s41591-025-04137-0. Online ahead of print.ABSTRACTDrug use disorders (DUDs) are emerging global public health challenges. Here we investigated the global and regional estimates of the prevalence and burden of DUDs, including amphetamine, cannabis, cocaine and opioi
Nat Med. 2026 Jan 16. doi: 10.1038/s41591-025-04169-6. Online ahead of print.ABSTRACTDespite advances in lipid-lowering treatment, atherosclerotic cardiovascular disease remains the leading cause of mortality, underscoring the need to address residual risk. Targeting both the synthesis and clearance
Hypertens Res. 2026 Jan 16. doi: 10.1038/s41440-025-02515-2. Online ahead of print.ABSTRACTIt remains unclear whether poor cardiovascular outcomes are associated with the longitudinal changes in inter-arm blood pressure (BP) difference. We aimed to investigate the role of repeated BP measurement in
Sci Rep. 2026 Jan 16. doi: 10.1038/s41598-026-36408-2. Online ahead of print.ABSTRACTHodgkin lymphoma (HL) is one of the most common cancers during adolescence. Advances in treatment have achieved survival rates exceeding 90%. However, long-term treatment-related sequelae, including cardiovascular d
Nat Commun. 2026 Jan 16. doi: 10.1038/s41467-026-68526-w. Online ahead of print.ABSTRACTSclerostin, which has three loops, inhibits bone formation and impairs whole-body lipid and glucose metabolism. The marketed therapeutic sclerostin antibody for postmenopausal osteoporosis (POP) mainly targeting
No abstractSci Rep. 2026 Jan 16. doi: 10.1038/s41598-025-34962-9. Online ahead of print.NO ABSTRACTPMID:41545410 | DOI:10.1038/s41598-025-34962-9
Sci Rep. 2026 Jan 16. doi: 10.1038/s41598-025-34972-7. Online ahead of print.ABSTRACTThe left atrium (LA) plays a pivotal role in modulating left ventricular filling, yet its hemodynamics remain poorly understood due to the limitations of conventional ultrasound analysis. Four-dimensional flow magne
NPJ Genom Med. 2026 Jan 16. doi: 10.1038/s41525-025-00540-1. Online ahead of print.ABSTRACTFabry disease (FD) is a rare X-linked lysosomal storage disorder caused by variants in the alpha-galactosidase A gene (GLA). Cardiac complications are a major cause of mortality, but the large number of varian
Bone Res. 2026 Jan 16;14(1):7. doi: 10.1038/s41413-025-00486-1.ABSTRACTAfter injury, bone tissue initiates a reparative response to restore its structure and function. The failure to initiate or delay this response could result in fracture nonunion. The molecular mechanisms underlying the occurrence
Cell Death Dis. 2026 Jan 16;17(1):46. doi: 10.1038/s41419-025-08246-z.ABSTRACTMultiple myeloma (MM) cells originate from antibody-producing plasma cells and endure chronic oxidative and proteotoxic stress due to the excessive production of immunoglobulins and free light chains. We previously demonst
