Acute coronary syndrome with plaque erosion: clinical characteristics, mechanisms, and unmet needs

Eur Heart J. 2025 Dec 12:ehaf1004. doi: 10.1093/eurheartj/ehaf1004. Online ahead of print.ABSTRACTCoronary plaque erosion is the second most common mechanism causing acute coronary syndromes (ACS), after coronary plaque rupture, accounting for approximately one-third of all ACS cases. The prevalence

D Denitsa Meteva

A plain language review of the ATTRibute-CM study: efficacy and safety of acoramidis in transthyretin amyloid cardiomyopathy

No abstractFuture Cardiol. 2025 Dec 12:1-9. doi: 10.1080/14796678.2025.2591426. Online ahead of print.NO ABSTRACTPMID:41384357 | DOI:10.1080/14796678.2025.2591426

J Julian D Gillmore

Small molecule inhibitors of HG-induced VEC ferroptosis: synthetic advances and therapeutic applications

Future Med Chem. 2025 Dec 12:1-14. doi: 10.1080/17568919.2025.2602422. Online ahead of print.ABSTRACTFerroptosis is a form of Regulated Cell Death (RCD) found in recent years. Its typical characteristics are the abnormal accumulation of intracellular iron ions and the accumulation of lipid peroxidat

Y Yu-Xi Zheng

VAPB Promotes Osteogenic Differentiation in Aortic Valve Interstitial Cells via Activation of the SMAD Signaling Pathway

Curr Med Chem. 2026;33(6):e09298673355591. doi: 10.2174/0109298673355591250121085134.ABSTRACTOBJECTIVE: Prior studies have associated vesicle-associated membrane protein- associated protein B (VAPB) with various cardiovascular diseases, yet its role in calcific Aortic Valve Disease (CAVD) is not ful

X Xiaolin Liu

Nanomaterials and exercise interventions: A synergistic approach for atherosclerosis therapy (Review)

Int J Mol Med. 2026 Feb;57(2):44. doi: 10.3892/ijmm.2025.5715. Epub 2025 Dec 12.ABSTRACTAtherosclerosis constitutes the fundamental pathological basis for cardiovascular diseases, with its pathogenesis intricately associated with dysfunctions in vascular endothelial and smooth muscle cells. Nanomate

Q Quanquan Zhou

Lactylation-mediated ferroptosis: A novel mechanism and therapeutic prospects in human diseases (Review)

Int J Mol Med. 2026 Feb;57(2):42. doi: 10.3892/ijmm.2025.5713. Epub 2025 Dec 12.ABSTRACTLysine lactylation (Kla), an emerging post‑translational modification, bidirectionally regulates cell fate decisions through epigenetic reprogramming and the direct modification of key ferroptosis proteins. It dr

Z Zhengjun Lin

Deciphering epigenetic regulation in cardiac developmental toxicity: Mechanisms and implications (Review)

Mol Med Rep. 2026 Feb;33(2):66. doi: 10.3892/mmr.2025.13776. Epub 2025 Dec 12.ABSTRACTAs the first functional organ to form during vertebrate embryogenesis, the heart exhibits heightened susceptibility to developmental toxicity. Epigenetic regulatory mechanisms, including DNA methylation, histone mo

Z Ziling Qin

A Rare Case of Aerococcus urinae Mitral Valve Infective Endocarditis With Multiple Septic Emboli to the Brain

Cureus. 2025 Nov 10;17(11):e96475. doi: 10.7759/cureus.96475. eCollection 2025 Nov.ABSTRACTAerococcus urinae is a rarely encountered Gram-positive bacterium that primarily causes urinary tract infections (UTIs), but in rare cases, it can result in bloodstream infections such as bacteremia, infective

S Saif M Srouji

Tailoring Anesthesia for Cardiac Amyloidosis: A Case Report Highlighting Perioperative Challenges

Cureus. 2025 Nov 10;17(11):e96512. doi: 10.7759/cureus.96512. eCollection 2025 Nov.ABSTRACTCardiac amyloidosis is a cause of restrictive cardiomyopathy, posing significant challenges in perioperative care. We report the case of an 85-year-old male with wild-type transthyretin amyloidosis (ATTRwt) un

A Ana Sofia M Fernandes

Sodium-Glucose Cotransporter-2 (SGLT2) Inhibitors and Risk of Heart Failure Hospitalization in Type 2 Diabetes: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Cureus. 2025 Nov 9;17(11):e96456. doi: 10.7759/cureus.96456. eCollection 2025 Nov.ABSTRACTSodium-glucose cotransporter-2 (SGLT2) inhibitors have emerged as a transformative therapy in type 2 diabetes mellitus (T2DM), offering benefits that extend beyond glycemic control. We conducted a meta-analysis

I Iman Joher

Evaluation of the Analytical Performance of a High-Precision Immunoassay for the Creatine Kinase-MB Isoenzyme

Cureus. 2025 Nov 9;17(11):e96457. doi: 10.7759/cureus.96457. eCollection 2025 Nov.ABSTRACTBackground Creatine kinase-MB isoenzyme (CK-MB) is an important biomarker for diagnosing myocardial injury. Although cardiac troponin is widely used as the primary biomarker for myocardial infarction, CK-MB mea

Y Yukina Kawada

Determinants of Hypertension Among Transport Workers in Ibadan, Nigeria: A Structural Equation Modeling Approach

Cureus. 2025 Nov 9;17(11):e96458. doi: 10.7759/cureus.96458. eCollection 2025 Nov.ABSTRACTIntroduction Hypertension is one of the most potent risk factors for cardiovascular disease (CVD). Transport workers are frequently exposed to multiple health risks, and undiagnosed hypertension among commercia

O Olajide Akinpeloye

From trash to sensor: banana peel-derived silver nanocomposite as a mimic enzyme for cholesterol detection and antibacterial applications

RSC Adv. 2025 Dec 10;15(57):49288-49300. doi: 10.1039/d5ra07350b. eCollection 2025 Dec 8.ABSTRACTCholesterol is the main building block of biological membranes and also a precursor of vitamin D, bile acids, and hormones. However, its abnormal concentration causes cardiovascular diseases, hypertensio

S Salman Ullah

Deferiprone therapy improves the oxidative status of LDL in patients with β-thalassaemia/HbE

Drugs Context. 2025 Dec 2;14:2025-7-6. doi: 10.7573/dic.2025-7-6. eCollection 2025.ABSTRACTBACKGROUND: Oxidative modifications of low-density lipoproteins (LDL) have been reported in patients with β-thalassaemia/haemoglobin E (HbE) and are related to cardiovascular complications. Deferiprone (L1) is

N Ngan Thi Tran

Lifetime Cannabis, Non-Cigarette Tobacco, and Illicit Drug Use and Cardiovascular Disease Among Young and Middle-Aged U.S. Adults

Am J Lifestyle Med. 2025 Dec 9:15598276251404883. doi: 10.1177/15598276251404883. Online ahead of print.ABSTRACTBackground: Despite increases in cardiovascular disease (CVD) prevalence among young and middle-aged adults in the United States (U.S.), associations between lifetime use of cannabis, non-

O Osayande Agbonlahor

L-GILZ is essential for cardiac function and protects against pressure overload-induced hypertrophy and dysfunction in mice

Asian Heart J. 2025 Jun;1(1):44-52. doi: 10.1097/ah9.0000000000000011. Epub 2025 Jun 30.ABSTRACTOBJECTIVE: Glucocorticoid-induced leucine zipper (GILZ) deficiency has been shown to exacerbate angiotensin-induced cardiomyocyte hypertrophy and diastolic dysfunction. However, the specific role of the l

H Hai Ying Fu

Transcriptomic profiling of diabetic retinopathy: insights into RPL11 and bisphenol A

Front Endocrinol (Lausanne). 2025 Nov 26;16:1705233. doi: 10.3389/fendo.2025.1705233. eCollection 2025.ABSTRACTBACKGROUND: Diabetic retinopathy (DR) is a leading microvascular complication of diabetes mellitus, causing irreversible vision loss in adults worldwide. However, the molecular mechanisms u

J Jian Zhang

Comparative analysis of the therapeutic effect of antibiotic bone cement on Wagner grade 3 or 4 diabetic foot ulcer in heel and non-heel areas: a retrospective cohort study

Front Endocrinol (Lausanne). 2025 Nov 26;16:1662731. doi: 10.3389/fendo.2025.1662731. eCollection 2025.ABSTRACTBACKGROUND: Heel diabetic foot ulcers (hDFU) represent a particularly severe form of DFU, characterized by prolonged healing times and a significantly elevated risk of major amputation. Eff

Y Yang Jian

Association between vascular aging and cardiovascular-kidney-metabolic syndrome

Front Endocrinol (Lausanne). 2025 Nov 26;16:1665836. doi: 10.3389/fendo.2025.1665836. eCollection 2025.ABSTRACTBACKGROUND: The concept of Cardiovascular-Kidney-Metabolic syndrome (CKM), an intricate interplay among metabolic risk factors, chronic kidney disease (CKD), and the cardiovascular system,

S Shuyi Zeng

Mediterranean Diet as a Therapeutic Strategy for Hypertension and Cardiovascular Health

Int J Hypertens. 2025 Dec 3;2025:2369674. doi: 10.1155/ijhy/2369674. eCollection 2025.ABSTRACTBACKGROUND: The Mediterranean diet (MedDiet) is a well-established cardioprotective dietary pattern with demonstrated efficacy in managing hypertension (HTN) and cardiovascular disease (CVD). Its rich array

S Situmbeko Liweleya

Association of maternal pre-existing atherosclerotic cardiovascular disease and neonatal and long-term offspring outcomes: a nationwide mother-child paired cohort

Hum Reprod Open. 2025 Nov 25;2025(4):hoaf074. doi: 10.1093/hropen/hoaf074. eCollection 2025.ABSTRACTSTUDY QUESTION: Is maternal pre-existing atherosclerotic cardiovascular disease (ASCVD) associated with neonatal and long-term offspring outcomes?SUMMARY ANSWER: Maternal pre-existing ASCVD is indepen

D Danbee Kang

The "Leicester, Leicestershire, and RUtland Chronic Kidney Disease Integrated Care Delivery Project" (LUCID) programme update: the impact on novel kidney therapies

No abstractClin Kidney J. 2025 Oct 6;18(12):sfaf312. doi: 10.1093/ckj/sfaf312. eCollection 2025 Dec.NO ABSTRACTPMID:41383906 | PMC:PMC12690196 | DOI:10.1093/ckj/sfaf312

R Rupert W Major

Magnetic resonance imaging determination of tissue sodium across the CKD spectrum-associations and implications for health

CONCLUSION: Whole leg-tissue Na^(+) in addition to skin Na^(+) concentration may be a useful clinical marker of body Na^(+) with related health outcomes. Tissue Na^(+) may play a role in CVD, bone health and quality of life in people with CKD, representing a potential therapeutic target to improve c

K Kylie Martin

Exploring left ventricle dimensions and interventricular septum thickness in the Iranian population: A comparative analysis through ECG gated, CT angiography and echocardiography

Caspian J Intern Med. 2025 Oct 15;16(4):692-699. doi: 10.22088/cjim.16.4.692. eCollection 2025 Fall.ABSTRACTBACKGROUND: Cardiovascular diseases (CVDs) are a significant cause of morbidity and mortality worldwide, particularly among the Iranian population. Assessing left ventricular (LV) dimensions a

N Naser Khezerlouy-Aghdam