Evaluation of Peripapillary Vitreous Dynamics in Patients with Acute Nonarteritic Anterior Ischemic Optic Neuropathy

Turk J Ophthalmol. 2026 Oct 23;56(5):325-331. doi: 10.4274/tjo.galenos.2026.62254.ABSTRACTOBJECTIVES: To evaluate peripapillary and vitreomacular interface configurations using spectral-domain optical coherence tomography (SD-OCT) in patients with acute nonarteritic anterior ischemic optic neuropath

G Gözde Orman

NOR-1 is an upstream regulator of Ca2+ homeostasis and calmodulin kinase II-dependent arrhythmogenesis

Cardiovasc Res. 2026 Oct 26:cvag240. doi: 10.1093/cvr/cvag240. Online ahead of print.ABSTRACTAIMS: Dysregulation of NOR-1 has been reported in cardiovascular diseases associated with altered calcium handling. We therefore investigated how NOR-1 affects calcium homeostasis and arrhythmogenesis to ide

P Paula Vázquez-Sufuentes

Circadian-Based Optimization of Pharmacotherapy in Chronic Diseases: Integrating Pharmacokinetics, Pharmacodynamics, and Disease Rhythm

Cureus. 2026 Sep 25;18(9):e116920. doi: 10.7759/cureus.116920. eCollection 2026 Sep.ABSTRACTCircadian rhythms are endogenous, approximately 24-hour biological cycles that regulate physiological processes, including cardiovascular function, metabolism, immune activity, endocrine signaling, and sleep-

M Monashri C

Nanodelivery of Brucine in Myocardial Ischemia-Reperfusion Injury: Mitochondrial PANoptosis, Cardiotoxicity, and Translational Barriers

Int J Nanomedicine. 2026 Oct 21;21:616055. doi: 10.2147/IJN.S616055. eCollection 2026.ABSTRACTMyocardial ischemia-reperfusion injury remains a major unresolved component of infarct expansion after timely restoration of coronary blood flow. Brucine, a toxic alkaloid from Strychnos nux-vomica L. is an

Y Yi Guo

Holter-Detected Arrhythmias in Acute Exacerbations of COPD: NT-proBNP Correlates and Hypercapnia Associated with COPD-Related Readmission

Int J Chron Obstruct Pulmon Dis. 2026 Oct 21;21:642161. doi: 10.2147/COPD.S642161. eCollection 2026.ABSTRACTBACKGROUND: Cardiac arrhythmias are increasingly recognized during acute exacerbations of chronic obstructive pulmonary disease (AECOPD), but their full spectrum and prognostic significance de

N Nan Ding

CONQUEST-ADVANCE: Achieving proDuctiVe implementAtioN of CONQUEST Quality Standards in COPD Care

Pragmat Obs Res. 2026 Oct 21;17:601059. doi: 10.2147/POR.S601059. eCollection 2026.ABSTRACTBACKGROUND: Integrated COPD management has improved outcomes for patients with diagnosed COPD. The CONQUEST Quality Improvement Program aims to improve the diagnosis and management for patients with potential

E Elango Vijaykumar

Depression and Heart Failure With Preserved Ejection Fraction: An Inflammatory Perspective

Depress Anxiety. 2026 Oct 25;2026:7169650. doi: 10.1155/da/7169650. eCollection 2026.ABSTRACTDepression is a common comorbidity in patients with heart failure with preserved ejection fraction (HFpEF), suggesting potential epidemiological and pathophysiological connections between these two age-relat

H Hongfan Chen

Long-Term Cardiovascular, Thromboembolic, and Malignancy Safety of Janus Kinase (JAK) Inhibitors in Dermatologic and Rheumatologic Populations: A Narrative Comparative Review

Cureus. 2026 Sep 25;18(9):e116911. doi: 10.7759/cureus.116911. eCollection 2026 Sep.ABSTRACTJanus kinase inhibitors are increasingly used in dermatology and rheumatology, but concerns about cardiovascular events, thromboembolism, and malignancy continue to influence long-term treatment decisions. Th

S Shakira Bou Rolon

Negative impact of single housing on chronic kidney disease mineral and bone disorder outcomes

JBMR Plus. 2026 Oct 24;10(11):ziag160. doi: 10.1093/jbmrpl/ziag160. eCollection 2026 Nov.ABSTRACTChronic kidney disease (CKD) is a disorder of acquired disrupted mineral metabolism that affects millions in the United States and has no cure. Due to disturbed mineral homeostasis bones are particularly

E Erica L Clinkenbeard

Physiologically Based Pharmacokinetic Modeling to Predict Drug-Drug Interactions of Aficamten in the Chinese Population

Drug Des Devel Ther. 2026 Oct 21;20:637138. doi: 10.2147/DDDT.S637138. eCollection 2026.ABSTRACTBACKGROUND: Aficamten is a next-generation cardiac myosin inhibitor (CMI) developed for the treatment of obstructive hypertrophic cardiomyopathy (oHCM). Although extensive clinical pharmacology studies ha

Z Ziyang Wang

Targeting Metabolic Drivers of Cardiovascular Disease: Insights for Therapeutic Innovation

Drug Des Devel Ther. 2026 Oct 21;20:611903. doi: 10.2147/DDDT.S611903. eCollection 2026.ABSTRACTCardiovascular disease (CVD) remains the leading cause of death worldwide, and metabolic dysfunction is increasingly recognized as an important component of its pathophysiology. Clinical evidence supports

U Urna Kansakar

Cardiorespiratory Arrest in the Context of Graves' Disease: A Rare Presentation

Cureus. 2026 Oct 25;18(10):e118542. doi: 10.7759/cureus.118542. eCollection 2026 Oct.ABSTRACTThyroid storm is the most severe and life-threatening expression of thyrotoxicosis, and its diagnosis remains clinical. Although sinus tachycardia and atrial fibrillation dominate its cardiovascular manifest

M Mariana Marques

HADS-Assessed Anxiety/Depression Status and Ocular Outcomes in Vision-Threatening Diabetic Retinopathy: A Multicenter Retrospective Cohort Study

Depress Anxiety. 2026 Oct 25;2026:6998782. doi: 10.1155/da/6998782. eCollection 2026.ABSTRACTPURPOSE: Vision-threatening diabetic retinopathy (VTDR) poses significant blindness risks and the study aimed to identify the impact of psychological factors on its ocular outcomes.METHODS: This retrospectiv

B Bo Li

Targeting CCR2 and PTPN22 Genes for Post-Infarct Heart Failure Therapy: A Network-based Repurposing of Kuanxiong Aerosol

Iran J Biotechnol. 2026 Oct 1;24(4):e4417. doi: 10.30498/ijb.2026.580398.4417. eCollection 2026 Oct.ABSTRACTBACKGROUND: Kuanxiong aerosol (KX) has been used in ischemic cardiovascular diseases, but its potential molecular targets and pathway-level associations in post-myocardial infarction heart fai

Z Zhifei Sun

Effects of Psycho-Cardiology Model-Based Psychological and Behavioural Management on Negative Emotions and Sleep Disorders in Patients With Resistant Hypertension Complicated by Anxiety and Depression

Actas Esp Psiquiatr. 2026 Oct 15;54(5):1379-1389. doi: 10.62641/aep.2241.ABSTRACTBACKGROUND: To explore the effect of psychocardiology model-based psychological and behavioural management on top of routine cardiovascular treatment on negative emotions and sleep disorders in patients with resistant h

L Liyan Zhu

Neurodevelopmental Trajectories and Neurodevelopmental Disorders Following Neonatal Intracranial Hemorrhage: A Long-Term Follow-Up Study and Analysis of Influencing Factors

Actas Esp Psiquiatr. 2026 Oct 15;54(5):1493-1503. doi: 10.62641/aep.2298.ABSTRACTBACKGROUND: To investigate the neurodevelopmental trajectories, the incidence of neurodevelopmental disorders, and associated influencing factors in children following neonatal intracranial hemorrhage (ICH), thereby pro

S Su Lin

Associations of Combined Transcranial Magnetic Stimulation and Transcranial Direct Current Stimulation With Psychological and Functional Outcomes After Stroke: A Retrospective Cohort Study

Actas Esp Psiquiatr. 2026 Oct 15;54(5):1627-1640. doi: 10.62641/aep.2337.ABSTRACTBACKGROUND: To examine whether combined transcranial magnetic stimulation (TMS) and transcranial direct current stimulation (tDCS), delivered with standard rehabilitation, was associated with post-stroke depression and

Y Yuehao Wu

Joint Association of Longitudinal Single-Point Insulin Sensitivity Estimator Patterns and Hypertension Status with Incident Stroke Among Adults with Cardiovascular-Kidney-Metabolic Syndrome Stages 0-3: A Nationwide Prospective Cohort Study

Balkan Med J. 2026 Oct 26. doi: 10.4274/balkanmedj.galenos.2026.2026-8-48. Online ahead of print.ABSTRACTBACKGROUND: The prognostic value of longitudinal single-point insulin sensitivity estimator (SPISE) patterns for stroke, particularly when considered in combination with hypertension (HTN), remai

J Jibo Sun

Achieving Risk-Specific Absolute LDL-C Threshold with PCSK9 Inhibitors: A Real-World, Single-Center Analysis

Rom J Intern Med. 2026 Oct 26. doi: 10.2478/rjim-2026-0025. Online ahead of print.ABSTRACTINTRODUCTION: Proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors emerged as an effective treatment for hypercholesterolemia in clinical trials, however real-world evidence shows considerable heter

D Dana Mihaela Ciobanu

Clinical Outcomes of Patients Hospitalized With Diabetic Foot Ulcer at a Tertiary Hospital in Ethiopia: A 5-Year Retrospective Audit

Int Wound J. 2026 Oct;23(10):e71086. doi: 10.1111/iwj.71086.ABSTRACTDiabetic foot ulcer is a major cause of hospitalization and lower extremity amputation, particularly in low-resource settings where patients frequently present with advanced wound. This study assessed the clinical outcomes of patien

M Melaku Taye Amogne

Effectiveness of Digital Commitment Devices in Improving Lifestyle and Cardiometabolic Outcomes in Adults with Cardiometabolic Risk Factors: A Systematic Review and Meta-Analysis

Eur J Prev Cardiol. 2026 Oct 26:zwag534. doi: 10.1093/eurjpc/zwag534. Online ahead of print.ABSTRACTAIM: Lifestyle modification is crucial for cardiovascular disease prevention but remains challenging due to complex behavioural factors such as the intention-behaviour gap. Digital commitment devices

R Ri Jie Chen

Comparison of Optical Coherence Tomography Biomarkers in Nonproliferative and Proliferative Diabetic Retinopathy: Marmasia Study Group Report No. 2

Turk J Ophthalmol. 2026 Oct 23;56(5):308-316. doi: 10.4274/tjo.galenos.2026.24196.ABSTRACTOBJECTIVES: To compare structural optical coherence tomography (OCT) biomarkers and visual acuity between eyes with nonproliferative (NPDR) and proliferative diabetic retinopathy (PDR) in real-life clinical set

I Işılay Özsoy Saygın

Efficacy and Safety of Apixaban Thromboprophylaxis According to Baseline Chemotherapy Class in High-Risk Ambulatory Cancer Patients: A Post Hoc Analysis of the AVERT Trial

Cancer Med. 2026 Nov;15(11):e72423. doi: 10.1002/cam4.72423.ABSTRACTBACKGROUND: Venous thromboembolism (VTE) is a leading cause of morbidity and mortality in cancer patients. The AVERT trial showed apixaban thromboprophylaxis reduced VTE in intermediate-to-high-risk patients initiating chemotherapy.

N Nadia Linxi Feng

Mechanism of Si Ni Decoction in Stabilizing Atherosclerotic Plaques in the Lower Extremities by Regulating Macrophage Polarization via NCOR1 Mitophagy

Immun Inflamm Dis. 2026 Oct;14(10):e70546. doi: 10.1002/iid3.70546.ABSTRACTINTRODUCTION: Si Ni decoction (SND) is known for its anti-inflammatory, immune-regulating, and microcirculation-improving effects. However, the molecular mechanisms underlying its role in atherosclerosis (AS) remain unclear.

Z Zhe Liu