Statin Therapy for Primary Prevention and Clinical Outcomes in Adults Aged 80 and Older: A Retrospective Comparative Cohort Study

J Am Geriatr Soc. 2026 Mar 7. doi: 10.1111/jgs.70375. Online ahead of print.ABSTRACTBACKGROUND: Evidence supporting the use of statins for primary prevention of cardiovascular disease (CVD) in individuals aged ≥ 80 years remains limited. This study aimed to evaluate the long-term clinical benefits a

O Ophir Lavon

Clonal haematopoiesis in chronic lymphocytic leukaemia: Biology, inflammaging and clinical implications in the era of targeted therapy

Clin Transl Med. 2026 Mar;16(3):e70633. doi: 10.1002/ctm2.70633.ABSTRACTBACKGROUND: Clonal haematopoiesis (CH) is an age-related condition increasingly recognised for its relevance in haematologic malignancies. In chronic lymphocytic leukaemia (CLL), its prevalence and clinical implications are gain

E Enrica Antonia Martino

The Impact of Study Size on COVID-19 Treatment Outcomes: A Meta-Epidemiological Study Comparing Large and Small Randomized Controlled Trials: A Systematic Review and Meta-Analyses

Rev Med Virol. 2026 Mar;36(2):e70125. doi: 10.1002/rmv.70125.ABSTRACTSmall randomized controlled trials (RCTs) in COVID-19 meta-analyses have been associated with more favourable treatment effects and reduced result stability. This study assessed how trial size impacts effect estimates, statistical

D Dong Hyun Kim

Impact of pulmonary-artery-to-aorta ratio on clinical outcomes in patients undergoing transcatheter aortic valve implantation: A retrospective study

Sci Prog. 2026 Jan-Mar;109(1):368504261431852. doi: 10.1177/00368504261431852. Epub 2026 Mar 7.ABSTRACTObjectivePulmonary-to-aortic diameter ratio (P/A) correlates with pulmonary hypertension (PH), which is linked to adverse outcomes. Our aim was to evaluate the impact of the P/A ratio, measured usi

Y Yang Wang

Association of ABO blood group and coronary heart disease in blood donors-Results from a cohort study in Australia

Transfusion. 2026 Mar 6. doi: 10.1111/trf.70147. Online ahead of print.ABSTRACTBACKGROUND: ABO blood groups may be associated with increased risk for several diseases including cardiovascular diseases (CVDs), particularly coronary heart disease (CHD). The role of other significant blood group system

S Surendra Karki

Inferior-Lead Lambda (λ) Wave Revealing Critical Right Coronary Artery Stenosis: A Case Report

Ann Noninvasive Electrocardiol. 2026 Mar;31(2):e70169. doi: 10.1111/anec.70169.ABSTRACTLambda (λ) waves are uncommon ECG markers of malignant arrhythmias, usually associated with channelopathies or transient ischemia. We report a 34-year-old man with recurrent syncope preceded by subxiphoid chest pa

J Jian Xiong

Association of admission serum potassium levels with mortality according to renal function in coronary artery disease: a prospective cohort study

Eur J Med Res. 2026 Mar 6. doi: 10.1186/s40001-026-04140-2. Online ahead of print.ABSTRACTBACKGROUND: Serum potassium levels are regulated by renal function; however, the extent to which the association with mortality is affected by renal function remains unknown. We aimed to explore the association

Y Yufei Ma

Decreased concentration of transcription factor 21 in patients with chronic schizophrenia is associated with an increased coronary artery calcium score

BMC Psychiatry. 2026 Mar 6. doi: 10.1186/s12888-026-07952-y. Online ahead of print.ABSTRACTBACKGROUND: Transcription factor 21 (TCF21) encodes a basic-helix-loop-helix transcription factor that is thought to play a vital role in epicardial progenitor cell development, with these cells differentiatin

T Thung-Lip Lee

Differential associations of transient hyperuricemia and transient hypouricemia with annual changes in estimated glomerular filtration rate in healthy participants: an observational study

BMC Nephrol. 2026 Mar 6. doi: 10.1186/s12882-026-04875-4. Online ahead of print.ABSTRACTBACKGROUND: Dysuricemia, encompassing both hyperuricemia (serum uric acid: SUA > 7 mg/dl) and hypouricemia (SUA ≤ 3 mg/dL), has been linked to cardio-renal risks, but it remains unclear whether consistent or tran

N Naoyuki Otani

Healthcare activities before familial hypercholesterolemia diagnosis: a nationwide register-based study in Denmark

No abstractBMC Prim Care. 2026 Mar 6. doi: 10.1186/s12875-026-03256-y. Online ahead of print.NO ABSTRACTPMID:41792624 | DOI:10.1186/s12875-026-03256-y

S Simon Graff

Correction: Natriuretic peptide signaling as a therapeutic target in POTS: physiological opportunities and caveats

No abstractClin Auton Res. 2026 Mar 7. doi: 10.1007/s10286-026-01200-9. Online ahead of print.NO ABSTRACTPMID:41792582 | DOI:10.1007/s10286-026-01200-9

J Jens Jordan

Permanent Supportive Housing and Cardiovascular Outcomes Among Veterans Experiencing Homelessness: A Difference-in-Differences Analysis

J Gen Intern Med. 2026 Mar 6. doi: 10.1007/s11606-026-10219-7. Online ahead of print.ABSTRACTBACKGROUND: Veterans experiencing homelessness have a high burden of cardiovascular disease (CVD). Identifying approaches that can improve the health of this population is crucial.OBJECTIVE: The Department o

S Sameed Ahmed M Khatana

TREM2 in neurodegeneration and diseases

Mol Psychiatry. 2026 Mar 6. doi: 10.1038/s41380-026-03505-7. Online ahead of print.ABSTRACTTriggering receptor expressed on myeloid cells 2 (TREM2) is a cell surface transmembrane receptor from the TREM receptor family, predominantly expressed on the microglia in the central nervous system (CNS). TR

A Altaf A Abdulkhaliq

The network pharmacology prediction and experiment validation of Astragalus membranaceus for alleviating silicosis fibrosis via decreasing MMP9 and EGFR expression

Sci Rep. 2026 Mar 6. doi: 10.1038/s41598-026-42544-6. Online ahead of print.ABSTRACTTo investigate the molecular mechanism of Astragalus membranaceus (AM) in alleviating silicosis fibrosis using bioinformatics and in vitro experiments. Active ingredients of AM and their corresponding targets were re

A Anning Yang

Dietary restriction in aging and longevity

Nat Aging. 2026 Mar 6. doi: 10.1038/s43587-026-01091-5. Online ahead of print.ABSTRACTDifferent types of dietary restriction (DR) have been practiced by humans for religious and medical purposes for millennia, but only during the past three decades has the scientific study of DR at cellular and mole

T Tomas Schmauck-Medina

Estimated glucose disposal rate and cardiovascular risk in metabolically healthy adults: a nationwide prospective cohort study

Sci Rep. 2026 Mar 6. doi: 10.1038/s41598-026-41550-y. Online ahead of print.ABSTRACTTo investigate the association of estimated glucose disposal rate (eGDR) with CVD, including stroke and heart disease, in metabolically healthy adults. All data were drawn from the China Health and Retirement Longitu

W Wenbo Li

A preprocessing-enhanced stacking classifier for generalized cardiovascular disease detection across diverse datasets

No abstractSci Rep. 2026 Mar 6. doi: 10.1038/s41598-026-41042-z. Online ahead of print.NO ABSTRACTPMID:41792193 | DOI:10.1038/s41598-026-41042-z

A Adeel Ashraf

Multi-electron nitrobenzothiadiazole sp-conjugated-alkynyl covalent organic frameworks for ammonium-ion batteries

Nat Commun. 2026 Mar 7. doi: 10.1038/s41467-026-70370-x. Online ahead of print.ABSTRACTCovalent organic frameworks containing periodic redox-active motifs and conjugation structures are booming as competitive negative electrodes for ammonium-ion batteries. Introducing substantial single-electron act

Y Yumin Chen

COVID-19 Epidemic: The Turning Point in Ending Sudden Cardiac Death Among Chinese Doctors

J Coll Physicians Surg Pak. 2026 Jan;36(1):117-118. doi: 10.29271/jcpsp.2026.01.117.ABSTRACTSudden cardiac death (SCD) is a public health problem that affects people worldwide regardless of age and social groups. SCD is an unexpected, sudden death caused by cardiac reasons, which often occurs within

W Wei Xiong

Nomogram Model Development and Validation for Predicting 90-Day Functional Outcomes in Acute Ischaemic Stroke Patients Post-Endovascular Therapy

J Coll Physicians Surg Pak. 2026 Jan;36(1):43-50. doi: 10.29271/jcpsp.2026.01.43.ABSTRACTOBJECTIVE: To develop and validate a nomogram model based on LASSO-logistic regression to predict the 90-day functional prognosis of acute ischaemic stroke (AIS) patients after endovascular therapy (EVT).STUDY D

G Guizhi Zhang

Pax8-rtTA/LC1-Driven Inducible Ketohexokinase Deletion Protects Against High Fructose-Induced Metabolic Syndrome in Mice

Acta Physiol (Oxf). 2026 Apr;242(4):e70187. doi: 10.1111/apha.70187.ABSTRACTAIM: Excessive fructose consumption is strongly linked to metabolic syndrome. Dietary fructose is predominantly transported into cells through the solute carrier family 2 member 5 and/or member 2, and then metabolized by fru

X Xiaoli Yi

Family history of stroke and cardiovascular diseases in early-onset cryptogenic ischaemic stroke

Eur Stroke J. 2026 Mar 1;11(3):aakag013. doi: 10.1093/esj/aakag013.ABSTRACTBACKGROUND: Familial aggregation of stroke is well-documented, yet few studies have examined associations between stroke subtypes-particularly early-onset cryptogenic ischaemic stroke (eCIS)-and broader family history (FH) of

M Maximilian C Sihvo

Cardiovascular Disease Mortality Patterns Among People With Cancer in New South Wales, Australia: A Population-Wide Data Linkage Study

Cancer Med. 2026 Mar;15(3):e71568. doi: 10.1002/cam4.71568.ABSTRACTOBJECTIVE: To investigate cardiovascular disease (CVD) mortality patterns among people with cancer in New South Wales (NSW) compared to the NSW general population and trends over time.DESIGN: Population-wide retrospective data-linkag

M Md Mijanur Rahman

A multi-site analysis of advanced age and elevated glucose predicting composite cardiovascular events in patients with type II diabetes mellitus in Central Ethiopia: A five-year retrospective cohort study

J Natl Med Assoc. 2026 Feb 14:S0027-9684(26)00029-5. doi: 10.1016/j.jnma.2026.02.005. Online ahead of print.ABSTRACTBACKGROUND: Cardiovascular disease (CVD) is the leading cause of morbidity and mortality among patients with type 2 diabetes mellitus (T2DM). Advanced age and poor glycemic control are

S Sintayehu Samuel Lorato