Discontinuation of Renin-Angiotensin System Inhibitors and Risk of End-Stage Renal Disease and Cardiovascular Outcomes Among Patients With Type 2 Diabetes and Chronic Kidney Disease: A Nationwide Taiwanese Cohort Study

Pharmacoepidemiol Drug Saf. 2026 Feb;35(2):e70323. doi: 10.1002/pds.70323.ABSTRACTPURPOSE: This nationwide cohort study examined the effects of discontinuation versus continuation of renin-angiotensin system inhibitors (RASis) on major renal and cardiovascular outcomes after the estimated glomerular

Y Yaa-Hui Dong

Heart-Brain Axis: Subclinical Cardiovascular Changes and Brain Health

J Am Heart Assoc. 2026 Jan 30:e047458. doi: 10.1161/JAHA.125.047458. Online ahead of print.ABSTRACTComplex bidirectional interactions between the nervous and cardiovascular systems are integrated through the heart-brain axis, a physiological pathway that governs both neural regulation of cardiovascu

P Parnian Habibi

Investigating the biomarkers of diabetic-cardiomyopathy with the high mobility group box-1 as a potential anti-inflammatory therapeutic target: Systematic Review and meta-analysis

Front Endocrinol (Lausanne). 2026 Jan 14;16:1714219. doi: 10.3389/fendo.2025.1714219. eCollection 2025.ABSTRACTAIM: The aim was to carry out a preliminary investigation to identify new biomarkers and test the suitability of the pro-inflammatory nuclear protein, HMGB1, as a potential diagnostic or tr

R Ranmali Ranasinghe