JMIR Form Res. 2026 Aug 18;10:e97202. doi: 10.2196/97202.ABSTRACTBACKGROUND: Arteriovenous fistula (AVF) stenosis is an important complication of hemodialysis that may impair dialysis adequacy and patient outcomes. Conventional AVF monitoring relies largely on subjective physical assessment and may
J Spinal Cord Med. 2026 Aug 18:1-10. doi: 10.1080/10790268.2026.2709252. Online ahead of print.ABSTRACTOBJECTIVE: To describe arterial stiffness, ankle-brachial index (ABI), advanced glycation end products (AGE) and glycosylated hemoglobin (HbA1c) in middle-aged people with cervical and upper thorac
ESC Heart Fail. 2026 Aug 18:xvag220. doi: 10.1093/eschf/xvag220. Online ahead of print.ABSTRACTBACKGROUND: In the C-MIC II trial, C-MIC therapy improved outcomes in patients with heart failure (HF) with reduced ejection fraction (HFrEF). We evaluated whether differences in background HF medication a
Eur J Prev Cardiol. 2026 Aug 18:zwag430. doi: 10.1093/eurjpc/zwag430. Online ahead of print.ABSTRACTGlucagon-like peptide-1 (GLP-1) receptor agonists were initially developed as glucose-lowering therapies for type 2 diabetes mellitus but have progressively emerged as cardiometabolic agents with clin
Eur J Prev Cardiol. 2026 Aug 18:zwag426. doi: 10.1093/eurjpc/zwag426. Online ahead of print.ABSTRACTAIMS: Chronic inflammation associates with prevalent and short-term incident hypertension. The aim of this study is to determine whether baseline high-sensitivity C-reactive protein (hsCRP) independen
J Vis Exp. 2026 Jul 31;(233). doi: 10.3791/72056.ABSTRACTThis study evaluated the effectiveness and cost-effectiveness of Internet-based pharmaceutical care (IPC) incorporating patient-reported outcomes (PROs) in postoperative patients with pulmonary arterial hypertension associated with congenital
J Vis Exp. 2026 Jul 31;(233). doi: 10.3791/71630.ABSTRACTSalidroside exerts a broad spectrum of pharmacological activities and represents a promising drug candidate for multiple ailments, including myocardial ischemia-reperfusion injury, acute lung injury, and Alzheimer's disease; nonetheless, quant
Nurs Open. 2026 Aug;13(8):e70751. doi: 10.1002/nop2.70751.ABSTRACTAIM: This study aimed to examine clinical and catheter-related factors associated with peripherally inserted central catheter-related infection, with particular attention to the association between thrombus formation and infection occ
J Vis Exp. 2026 Jul 31;(233). doi: 10.3791/72019.ABSTRACTCilioretinal artery occlusion is an uncommon retinal vascular emergency that can cause acute monocular visual loss, particularly when the macular region is involved. Non-arteritic anterior ischemic optic neuropathy is another ischemic disorder
J Vis Exp. 2026 Aug 4;(234). doi: 10.3791/70237.ABSTRACTThis study examined the mechanisms underlying the comorbidity between type 2 diabetes mellitus (T2DM) and atherosclerotic cardiovascular disease (ASCVD), while identifying potential therapeutic targets. Common differentially expressed genes (C-
J Clin Pharmacol. 2026 Aug;66(8):e70248. doi: 10.1002/jcph.70248.ABSTRACTDespite the recent reports of the potential association between semaglutide and nonarteritic anterior ischemic optic neuropathy (NAION), available evidence remains inconclusive. We aimed to evaluate the relative effect (RE) of
J Vis Exp. 2026 Aug 4;(234). doi: 10.3791/71556.ABSTRACTIntracerebral hemorrhage (ICH) is a neurological disorder associated with high mortality and disability rates and can lead to severe neurological injury. This study investigated the role and underlying mechanism of FGD5-AS1 in ICH. In vitro and
J Vis Exp. 2026 Aug 4;(234). doi: 10.3791/72141.ABSTRACTThe saphenous vein is one of the most commonly used conduits in coronary artery bypass grafting (CABG). However, the high long-term failure rate limits its clinical efficacy. Although hemodynamic factors are widely believed to drive vein graft
J Vis Exp. 2026 Aug 4;(234). doi: 10.3791/70761.ABSTRACTNosocomial pulmonary infection is a frequent complication after spontaneous intracerebral hemorrhage and may worsen neurological recovery, prolong hospitalization, and increase clinical burden. This retrospective clinical-laboratory study prese
J Vis Exp. 2026 Aug 7;(234). doi: 10.3791/69851.ABSTRACTThrombolytic therapy has long been considered a relative contraindication during cardiopulmonary resuscitation (CPR), mainly due to concerns about fatal bleeding complications. However, in patients with acute myocardial infarction (AMI), untrea
Circ Genom Precis Med. 2026 Aug;19(4):e005447. doi: 10.1161/CIRCGEN.125.005447. Epub 2026 Aug 18.ABSTRACTThe advent of high-throughput sequencing technologies has revolutionized cardiovascular genetics, generating vast amounts of data. A major challenge in the genomic era is the efficient and accura
Tissue Factor (TF)^(pos)-platelets represent a subset of the platelet population. Recently, this subset has been shown to predict cardiovascular mortality in patients with coronary artery disease, establishing it as a biomarker useful for thrombotic risk stratification. Accurate quantification of TF
PLoS Pathog. 2026 Aug 18;22(8):e1014511. doi: 10.1371/journal.ppat.1014511. Online ahead of print.ABSTRACTCrimean-Congo hemorrhagic fever (CCHF), which is caused by infection with the CCHF virus (CCHFV), is the most widespread hemorrhagic infectious disease. In severe cases, liver damage is a salien
Sci Prog. 2026 Jul-Sep;109(3):368504261481031. doi: 10.1177/00368504261481031. Epub 2026 Aug 18.ABSTRACTObjectiveCoronary artery ectasia (CAE) and ascending thoracic aortic aneurysm (ATAA) are vascular dilative disorders with unclear lipid profiles. We compared lipid parameters among patients with C
J Vis Exp. 2026 Aug 7;(234). doi: 10.3791/71631.ABSTRACTInterstitial lung disease (ILD) and pulmonary hypertension (PH) frequently coexist as comorbidities, leading to poor clinical outcomes and limited therapeutic options. Identifying important research hotspots and uncovering key comorbidity targe
PLoS Comput Biol. 2026 Aug 18;22(8):e1014594. doi: 10.1371/journal.pcbi.1014594. eCollection 2026 Aug.ABSTRACTtRNA-derived small RNAs (tsRNAs) have emerged as a novel class of regulatory molecules implicated in the pathogenesis of numerous human diseases, positioning them as promising biomarkers and
J Cardiovasc Nurs. 2026 Aug 18. doi: 10.1097/JCN.0000000000001371. Online ahead of print.ABSTRACTBACKGROUND: Cardiovascular disease (CVD) and CVD risk factors, including obesity and hypertension, are increasingly prevalent among children and youth, highlighting the need for early sustained preventio
J Vis Exp. 2026 Aug 7;(234). doi: 10.3791/71532.ABSTRACTThis study describes a reproducible computational workflow for identifying endoplasmic reticulum stress (ERS)-related gene signatures in atrial fibrillation (AF) by integrating bulk transcriptomics, machine learning, immune infiltration analysi
PLOS Glob Public Health. 2026 Aug 18;6(8):e0006035. doi: 10.1371/journal.pgph.0006035. eCollection 2026.ABSTRACTHumanitarian crises disrupt the continuous care required for non-communicable diseases (NCDs), yet evidence on effective health-system responses remains fragmented. We conducted a scoping
