A Comparison of Machine Learning Algorithms for Predicting Hypertension Incidence Based on Cohort Study

Endocrinol Diabetes Metab. 2026 May;9(3):e70199. doi: 10.1002/edm2.70199.ABSTRACTOBJECTIVES: This study aimed to identify key hypertension (HTN) risk factors using machine learning (ML) models to enhance prediction accuracy.METHODS: Data from the Mashhad stroke and heart atherosclerotic disorder (MA

S Somayeh Ghiasi

Outcomes Among MM Patients Receiving Early Intervention for MRD Progression Following Autologous Stem Cell Transplantation

Cancer Med. 2026 May;15(5):e71911. doi: 10.1002/cam4.71911.ABSTRACTMinimal residual disease (MRD) testing is essential for evaluating treatment response among multiple myeloma (MM) patients. Many patients experience MRD progression (MRD-P) before they meet the criteria for clinical or biochemical pr

X Xiaozhe Li

Fatty Liver Disease in Australia: A Narrative Review on the Epidemiology, Natural History, Prognostication and Management in People With Metabolic Dysfunction

Med J Aust. 2026 May;224(5):e70195. doi: 10.5694/mja2.70195.ABSTRACTMetabolic (dysfunction)-associated fatty liver disease (MAFLD) or metabolic (dysfunction)-associated steatotic liver disease (MASLD) is the most common and fastest growing cause of chronic liver disease worldwide. There has been a s

K Karl Vaz

T-Cell Immunosenescence in Systemic Lupus Erythematosus: Molecular Mechanisms and Therapeutic Perspectives

Clin Rev Allergy Immunol. 2026 May 11;69(1):43. doi: 10.1007/s12016-026-09164-4.ABSTRACTSystemic lupus erythematosus (SLE) is a heterogeneous autoimmune disease characterized by chronic immune activation, relapsing-remitting clinical progression, and progressive multi-organ damage. In addition to th

S Suqing Zhou

The microRNA inhibitor CDR132L in patients with reduced left ventricular ejection fraction after myocardial infarction: a randomized phase 2 trial

Nat Med. 2026 May 10. doi: 10.1038/s41591-026-04408-4. Online ahead of print.ABSTRACTMicroRNA-132 (miR-132) is a central regulator of adverse cardiac remodeling. Here we evaluated CDR132L, a synthetic antisense oligonucleotide miR-132 inhibitor, in a multinational, randomized, double-blind, placebo-

J Johann Bauersachs

PNPLA3-I148M reduces hepatic triacylglycerol secretion and mitigates diet induced left ventricular diastolic dysfunction

Sci Rep. 2026 May 10. doi: 10.1038/s41598-026-47839-2. Online ahead of print.ABSTRACTPNPLA3-I148M, the greatest genetic determinant for metabolic dysfunction-associated steatotic liver disease (MASLD), paradoxically associates with reduced cardiovascular disease (CVD); however, the mechanisms are po

A Andrew J Butcko

Real-time, high-precision detection of aortic dissection key components for emergency triage using an enhanced deep learning model

Med Phys. 2026 May;53(5):e70461. doi: 10.1002/mp.70461.ABSTRACTBACKGROUND: Aortic dissection (AD) is a life-threatening cardiovascular emergency. For Type B AD (TBAD), rapid and accurate identification of the true lumen (TL), false lumen (FL), and false lumen thrombus (FLT) from CTA is critical for

H Houde Wu

Distinct gut microbiota signatures and predicted lipid metabolism pathways in Taiwanese patients with acute versus chronic coronary syndromes

J Formos Med Assoc. 2026 May 9:S0929-6646(26)00466-3. doi: 10.1016/j.jfma.2026.04.127. Online ahead of print.ABSTRACTBACKGROUND: The gut microbiota plays a pivotal role in host lipid metabolism and cardiovascular health. However, comparative profiling of microbial composition and predicted metabolic

W Wei-Ting Wang

Infectious complications of ANCA-associated vasculitis: Description and associated outcome

Eur J Intern Med. 2026 May 9:106931. doi: 10.1016/j.ejim.2026.106931. Online ahead of print.ABSTRACTINTRODUCTION: In ANCA-associated vasculitis (AAV), both the disease and its treatments contribute to systemic complications, among which, infections represent a major cause of morbidity and mortality.

J Jeanne Morin

Timing of Tyrosine Kinase Inhibitor Switching in Chronic Myeloid Leukemia: A Comparative Analysis of Early Versus Late Strategies

Clin Lymphoma Myeloma Leuk. 2026 Apr 14:S2152-2650(26)00101-1. doi: 10.1016/j.clml.2026.04.001. Online ahead of print.ABSTRACTBACKGROUND: Optimal timing for switching tyrosine kinase inhibitors (TKIs) in chronic myeloid leukemia (CML) remains uncertain. While early molecular milestones inform treatm

C Chidiebube Ugwu

Non-Randomised Comparative Analysis and Cost-Minimisation Analysis of Macrophage-Modulating Cream on Mildly Infected Diabetic Foot Ulcers: A Real-World Preliminary Report

Int Wound J. 2026 May;23(5):e70937. doi: 10.1111/iwj.70937.ABSTRACTDiabetic foot ulcers (DFUs) are serious complications of diabetes, characterised by impaired healing driven in part by pro-inflammatory macrophage activity. ON101, a topical macrophage-modulating cream, promotes M1-to-M2 transition a

C Chia-Ding Shih

Social Determinants of Health Reveal Heterogeneity in Associations Between AHA PREVENT Cardiovascular Disease Risk Equations and Mortality and Provide Incremental Discrimination for Mortality in US Adults

Diabetes Obes Metab. 2026 May 10. doi: 10.1111/dom.70838. Online ahead of print.ABSTRACTBACKGROUND: The American Heart Association (AHA) PREVENT equations provide contemporary estimates of 10-year cardiovascular disease (CVD) risk. Although PREVENT was developed to estimate incident CVD risk, its re

M Mingqing Kou

The Evolving Role of High-Sensitivity C-Reactive Protein for Mortality Prediction Across the Spectrum of Cardiovascular-Kidney-Metabolic Syndrome

Diabetes Obes Metab. 2026 May 10. doi: 10.1111/dom.70843. Online ahead of print.ABSTRACTAIMS: High-sensitivity C-reactive protein (hsCRP) is central to cardiovascular-kidney-metabolic (CKM) syndrome pathogenesis, but its prognostic value across progressive CKM stages remains uncertain. We aimed to e

J Jing Li

ANTIPHOSPHOLIPID SYNDROME AS A MODIFIER OF CLINICAL PHENOTYPES IN ATHEROSCLEROTIC CARDIOVASCULAR DISEASE: A CASE-CONTROL STUDY

Georgian Med News. 2026 Mar;(372):212-219.ABSTRACTBACKGROUND: Antiphospholipid syndrome (APS) is an autoimmune prothrombotic disorder characterized by persistent antiphospholipid antibodies and vascular thrombosis. Its contribution to clinical phenotypes of atherosclerotic cardiovascular disease (AS

N N Archaia

THE ROLE OF SOCIAL DEPRIVATION FACTORS AND QUALITY OF LIFE IN ADULTS WITH METABOLIC SYNDROME: A NARRATIVE REVIEW

Georgian Med News. 2026 Mar;(372):153-162.ABSTRACTINTRODUCTION: Metabolic syndrome (MetS) is characterized by a cluster of interconnected chronic conditions - abdominal obesity, dyslipidemia, insulin resistance, and hypertension. MetS is highly prevalent among adults and is closely associated with c

S S Skenderova

ADHERENCE TO PHARMACOTHERAPY STANDARDS FOR CHRONIC CARDIOVASCULAR AND RESPIRATORY DISEASES AMONG PRIMARY CARE PHYSICIANS IN THE SAMARKAND REGION

Georgian Med News. 2026 Mar;(372):48-54.ABSTRACTBACKGROUND: Guideline-based pharmacotherapy for chronic cardiovascular diseases and chronic respiratory diseases is a key determinant of outcomes in primary care; however, adherence may vary across territories due to organizational factors and access t

S S Khusinova

CORRELATIONS BETWEEN HOMOCYSTEINE AND VITAMIN B12 IN TYPE 2 DIABETES TREATED WITH METFORMIN

Georgian Med News. 2026 Mar;(372):6-12.ABSTRACTSTUDY OBJECTIVE: The study aimed to assess the prevalence of vitamin B12 deficiency in patients with type 2 diabetes mellitus treated with metformin, determine the relationship between serum vitamin B12 and homocysteine concentrations, and evaluate the

K K Dundua

The landscape of extracellular vesicle in periodontitis and associated systemic diseases: From pathological mechanisms to therapeutic opportunities

Int Immunopharmacol. 2026 May 9;182:116818. doi: 10.1016/j.intimp.2026.116818. Online ahead of print.ABSTRACTPeriodontitis, driven by microbial dysbiosis, causes progressive destruction of periodontal tissues through pathogenic bacteria-host interactions, and is also closely associated with a variet

H Honghui Yue

Cardiovascular and Hepatic Outcomes: Prognostic Differences Across MASLD-MetALD-ALD Continuum

Clin Mol Hepatol. 2026 May 8. doi: 10.3350/cmh.2026.0367. Online ahead of print.ABSTRACTA paradigm shift in fatty liver disease nomenclature has introduced steatotic liver disease (SLD) as an umbrella term, encompassing metabolic dysfunction-associated steatotic liver disease (MASLD), metabolic dysf

H Han Ah Lee

Dyspnea and fatigue in Long-COVID: definition of risk factors and of DLCO-based phenotypes in a multicenter study of 765 patients from Italy

Respir Med. 2026 May 8:108880. doi: 10.1016/j.rmed.2026.108880. Online ahead of print.ABSTRACTBACKGROUND: Dyspnea and fatigue represent common Long-COVID symptoms, but their presence is not always accompanied by lung function abnormalities. Aim of the study was to evaluate dyspnea and fatigue in rel

M Marco Floridia

Lipid lowering in Coronary Artery Disease - Not just statins

Clin Med (Lond). 2026 May 8:100594. doi: 10.1016/j.clinme.2026.100594. Online ahead of print.ABSTRACTCoronary artery disease has a high degree of morbidity and mortality internationally, and after a cardiovascular event, patients require intensified management of modifiable risk factors, with optima

J Jennie Han

High-Salt Diet Disrupts Mitochondria-Associated Endoplasmic Reticulum Membrane: A Unifying Mechanism Linking Nutrition to Systemic Pathologies

J Nutr. 2026 May 8:101589. doi: 10.1016/j.tjnut.2026.101589. Online ahead of print.ABSTRACTThe mitochondrial-associated endoplasmic reticulum membrane (MAM) is a dynamic contact site formed through protein-mediated connections between the endoplasmic reticulum (ER) and outer mitochondrial membrane.

H Hong-Li Han

TRPM8-dependent protective effects of L-menthol attenuates lipid overload-induced calcium dysregulation and mitochondrial dysfunction in mouse ventricular myocytes

J Mol Cell Cardiol. 2026 May 8:S0022-2828(26)00061-1. doi: 10.1016/j.yjmcc.2026.05.002. Online ahead of print.ABSTRACTCardiac injury from lipid overload features cardiomyocyte death, myocardial remodeling, and reduced contractile function. Although L-menthol has reported cardioprotective effects, it

X Xiang Sun

Heartbeats and hidden codes: Decoding cardiac aging with multi-omics and computational approaches

J Mol Cell Cardiol. 2026 May 8:S0022-2828(26)00064-7. doi: 10.1016/j.yjmcc.2026.05.005. Online ahead of print.ABSTRACTAging is a major risk factor for cardiovascular disease, yet the mechanisms driving age-related cardiac decline remain incompletely defined. Although traditional omics approaches hav

S Smin L Liu