An integrative single-nucleus multiomic atlas of the human left ventricle identifies gene regulatory network dynamics across cardiac development, aging, and disease
Genome Biol. 2026 Apr 6. doi: 10.1186/s13059-026-04061-7. Online ahead of print.ABSTRACTBACKGROUND: As the first organ to develop in utero, the human heart undergoes extensive molecular, structural and metabolic remodeling during development and must sustain its function throughout life.RESULTS: We

