Circ Cardiovasc Interv. 2026 Oct 31:e017029. doi: 10.1161/CIRCINTERVENTIONS.126.017029. Online ahead of print.ABSTRACTBACKGROUND: The BRIGHT-4 trial (Bivalirudin With Prolonged Full-Dose Infusion During Primary PCI Versus Heparin Trial-4) demonstrated that procedural anticoagulation with bivalirudin
Eur J Prev Cardiol. 2026 Oct 31:zwag577. doi: 10.1093/eurjpc/zwag577. Online ahead of print.ABSTRACTRecent clinical trials have reported an increased risk for atrial fibrillation (AF) in individuals treated with omega-3 fatty acids (FA). As virtually all these studies were conducted with pharmaceuti
Cell Rep. 2026 Oct 30;45(11):118234. doi: 10.1016/j.celrep.2026.118234. Online ahead of print.ABSTRACTLoss of cardiomyocytes drives cardiac remodeling and ultimately leads to heart failure, highlighting the need to promote cardiac regeneration. Exercise has been known to enhance cardiac repair and s
Curr Heart Fail Rep. 2026 Oct 31;23(1):53. doi: 10.1007/s11897-026-00785-6.ABSTRACTPURPOSE OF REVIEW: Heart failure (HF) and frailty are increasingly prevalent with population aging, frequently coexist, and share pathophysiological mechanisms. This review summarizes recent evidence on shared biologi
Endocrine. 2026 Oct 31;91(1):364. doi: 10.1007/s12020-026-04838-7.ABSTRACTPURPOSE: Maternal high-fat diet (HFD) exposure induces sex-dependent cardiac hypertrophy in adult offspring, but the underlying mechanisms remain unclear. This study investigated the role of miR-493-3p in maternal HFD-induced
Curr Med Sci. 2026 Oct 29. doi: 10.1007/s11596-026-00251-3. Online ahead of print.ABSTRACTThe accelerating aging of the global population has made aging and its related diseases major public health challenges in the 21st century. Adipose tissue is not only an energy reservoir but also a crucial endo
Cerebellum. 2026 Oct 31;25(6):165. doi: 10.1007/s12311-026-02108-w.ABSTRACTAtaxia-telangiectasia (A-T) causes progressive neurological disability. Following two phase III trials published in 2026, this study is an updated randomized evidence for pharmacological interventions targeting neurological m
Neurochem Res. 2026 Oct 31;51(6):320. doi: 10.1007/s11064-026-04933-1.ABSTRACTLipid droplet (LDs) accumulate in glial cells across neurodegenerative and ischemic brain pathologies. LDs modulate cellular stress via organelle crosstalk, particularly with lysosomes, whose dysfunction and cathepsin leak
Curr Atheroscler Rep. 2026 Oct 31;28(1):107. doi: 10.1007/s11883-026-01473-5.ABSTRACTPURPOSE OF REVIEW: Food insecurity affects 18.4% of US households with children and disproportionately impacts racial and ethnic minority and single-parent households. This review examines the association between ch
Rheumatol Int. 2026 Oct 31;46(11):298. doi: 10.1007/s00296-026-06338-3.ABSTRACTBehçet's syndrome is a heterogeneous disease with diverse patterns of organ involvement. We aimed to identify clinical subgroups using latent class analysis and evaluate clinical characteristics and treatment patterns acr
Geroscience. 2026 Oct 29. doi: 10.1007/s11357-026-02616-x. Online ahead of print.ABSTRACTBACKGROUND: Poorly controlled diabetes drives cardiovascular disease and mortality in India, a burden set to grow as the population ages rapidly. Evidence on geographic variation in diabetes care has focused on
Curr Hypertens Rep. 2026 Oct 31;28(1):46. doi: 10.1007/s11906-026-01397-0.ABSTRACTPURPOSE OF REVIEW: To review malignant left ventricular hypertrophy (LVH) as a dynamic, higher-risk phenotype within Stage B/pre-heart failure (HF), with a focus on its underlying biology, prognostic significance, and
Mol Biol Rep. 2026 Oct 29;53(1):1852. doi: 10.1007/s11033-026-12962-w.ABSTRACTOBJECTIVE: This study aimed to identify the role of inducible nitric oxide synthase (iNOS) in regulating endothelial cell (EC) function within the toll-like receptor 3 (TLR3) signaling pathway.METHODS: To activate TLR3 and
Mol Biol Rep. 2026 Oct 29;53(1):1855. doi: 10.1007/s11033-026-13036-7.ABSTRACTCalcific aortic valve disease (CAVD) is the most prevalent valvular heart disease in the Western countries and carries significant morbidity and mortality, yet no pharmacological therapy has demonstrated efficacy in modify
JACC Adv. 2026 Oct 14:103382. doi: 10.1016/j.jacadv.2026.103382. Online ahead of print.ABSTRACTBACKGROUND: Balloon pulmonary angioplasty (BPA) is an established treatment for inoperable chronic thromboembolic pulmonary hypertension; however, volume-outcome relationships remain unclear.OBJECTIVES: Th
No abstractJACC Cardiovasc Interv. 2026 Oct 31:S1936-8798(26)02905-5. doi: 10.1016/j.jcin.2026.10.009. Online ahead of print.NO ABSTRACTPMID:42965548 | DOI:10.1016/j.jcin.2026.10.009
J Magn Reson Imaging. 2026 Oct 31. doi: 10.1002/jmri.70605. Online ahead of print.ABSTRACTBACKGROUND: Coronary computed tomography angiography (CCTA) often overestimates stenosis in calcified plaques due to blooming artifacts. The performance of 5.0 T Coronary MR angiography (CMRA) in calcified arte
Gac Med Mex. 2025;162(2):173-178. doi: 10.24875/GMM.M26001123.ABSTRACTThe Cre-LoxP system is based on site-specific recombination mediated by the enzyme Cre recombinase. This system allows spatiotemporal control of gene expression in inducible models by utilizing specific promoters or enhancers that
Gac Med Mex. 2025;162(2):179-185. doi: 10.24875/GMM.25000078.ABSTRACTBACKGROUND: Aging results in a progressive decrease in the renal functional reserve; polypharmacy can have negative effects.OBJECTIVE: Analyze whether polypharmacy and other factors increase the probability of reduced glomerular fi
Clin Transl Med. 2026 Nov;16(11):e70870. doi: 10.1002/ctm2.70870.ABSTRACTBACKGROUND: Ischaemic stroke occurs when blood flow to the brain is obstructed. Rapid restoration of blood supply frequently induces cerebral ischaemia‒reperfusion injury (CIRI). Bone marrow mesenchymal stem cell (BMSC)-derived
Clin Cardiol. 2026 Nov;49(11):e70507. doi: 10.1002/clc.70507.ABSTRACTAIMS: Symptomatic chronic heart failure (HF) despite medical treatment can be addressed with cardiac contractility modulation (CCM) therapy, which has yet to have been investigated regarding outcome differences between early versus
Clin Cardiol. 2026 Nov;49(11):e70480. doi: 10.1002/clc.70480.ABSTRACTBACKGROUND: Patients with type 2 diabetes mellitus (T2DM) who experience acute coronary syndromes (ACS) remain at high risk for recurrent ischemic events despite secondary prevention. Lipoprotein(a) [Lp(a)] contributes to residual
Clin Cardiol. 2026 Nov;49(11):e70489. doi: 10.1002/clc.70489.ABSTRACTBACKGROUND: Heart failure with preserved ejection fraction (HFpEF) accounts for nearly half of all global heart failure cases. Historically viewed as a left-centric diastolic disorder, emerging evidence identifies right ventricular
J Vis Exp. 2026 Oct 30;(236). doi: 10.3791/71597.ABSTRACTVon Hippel-Lindau (VHL) disease is a rare autosomal dominant tumor syndrome caused by germline mutations in the VHL gene. Patients may develop multiple, bilateral, and recurrent renal cell carcinomas (RCCs), posing a major therapeutic challeng
