Prevalence and Characteristics of INOCA in Patients With Either Angiographically Normal Vessels or Non-Obstructive Coronary Atherosclerosis. Insights From the All-Comers Prospective AID-ANGIO Study

Catheter Cardiovasc Interv. 2026 Apr 30. doi: 10.1002/ccd.70644. Online ahead of print.ABSTRACTBACKGROUND: Myocardial ischemia of non-obstructive origin (INOCA) is a prevalent cause of chronic coronary syndromes (CCS). Risk factors for atherosclerosis have also been described to promote INOCA, raisi

A Adrián Jerónimo

Trajectory-Defined Thrombo-Inflammatory Phenotypes Predict 30-Day ICU Mortality in Post-cardiac Arrest Syndrome: A Multicenter Retrospective Longitudinal Cohort Study

Inquiry. 2026 Jan-Dec;63:1. doi: 10.1177/00469580261448815. Epub 2026 Apr 30.ABSTRACTCurrent risk stratification for Post-cardiac Arrest Syndrome (PCAS) relies mainly on static admission variables and may fail to capture the dynamic systemic evolution. This study aimed to identify trajectory-defined

G Guyu Zhang

Empagliflozin Ameliorates Angiotensin II-Induced Left Ventricular Diastolic Dysfunction by Suppressing EndoMT via PI3K/AKT/eNOS Signaling

J Gene Med. 2026 May;28(5):e70096. doi: 10.1002/jgm.70096.ABSTRACTBACKGROUND: The SGLT2 inhibitor empagliflozin (EMPA) has been found to reduce the combined risk of cardiovascular death or hospitalization for heart failure in patients with or without reduced left ventricular ejection fraction, irres

D Dong-Li Shen

Glucagon-Like Peptide-1 Receptor Agonists and Ocular Outcomes: Metabolic Transition, Retinal Vulnerability, and Risk-Stratified Monitoring

J Obes Metab Syndr. 2026 Apr 30;35(2):164-175. doi: 10.7570/jomes26012.ABSTRACTGlucagon-like peptide-1 receptor agonists (GLP-1 RAs) and dual incretin-based therapies provide marked reductions in glycosylated hemoglobin (HbA1c), body weight, and cardiovascular risk. As global adoption expands and re

S Su Jeong Song

The Effects of New Antidiabetic Drugs on the Course of Peripheral Arterial Occlusive Disease

Dtsch Arztebl Int. 2026 May 29;123(11):arztebl.m2026.0055. doi: 10.3238/arztebl.m2026.0055. Online ahead of print.ABSTRACTBACKGROUND: Peripheral arterial occlusive disease (PAOD) and diabetic foot syndrome (DFS) are the leading reasons for lower-limb amputation. The new antidiabetic drugs-GLP-1 rece

K Knut Kröger

Multiomics Analysis Reveals Stromal Cell State Changes and INHBA-Associated Remodeling in Calcific Aortic Valve Disease

Arterioscler Thromb Vasc Biol. 2026 Apr 30. doi: 10.1161/ATVBAHA.126.324799. Online ahead of print.ABSTRACTBACKGROUND: The cellular and molecular mechanisms underlying calcific aortic valve disease (CAVD) remain incompletely understood. Emerging evidence suggests that signaling components active dur

S Shilin Jin

Active Brown Adipose Tissue Is Associated With Reduced Arterial Inflammation and Less Atherogenic Circulating Factors in Individuals With Obesity

Arterioscler Thromb Vasc Biol. 2026 Apr 30. doi: 10.1161/ATVBAHA.125.324200. Online ahead of print.ABSTRACTBACKGROUND: Increasing evidence from preclinical models has linked the actions of brown adipose tissue (BAT) with protection against atherosclerosis and cardiovascular disease, in part due to i

O Oana C Kulterer

Endothelial DNA Damage Orchestrates Cardio-Kidney-Metabolic Dysfunction Through Endothelin-1 Signaling

Arterioscler Thromb Vasc Biol. 2026 Apr 30. doi: 10.1161/ATVBAHA.126.324564. Online ahead of print.ABSTRACTBACKGROUND: Cardiovascular diseases increase with aging and are closely linked to metabolic dysfunction and kidney disease through the cardiovascular-kidney-metabolic axis, but the underlying m

W Wataru Ito

Blood Pressure Change and Subclinical Target Organ Damage in Mid-Adulthood

Hypertension. 2026 Apr 30. doi: 10.1161/HYPERTENSIONAHA.125.26364. Online ahead of print.ABSTRACTBACKGROUND: Blood pressure (BP) is a dynamic trait associated with cardiovascular disease. We aimed to estimate age-specific BP levels and rates of change from childhood to mid-adulthood and to examine t

T Tongshuai Guo

Health Care Affordability in the United States, From Crisis to Action: A Presidential Advisory From the American Heart Association

Circulation. 2026 Apr 30. doi: 10.1161/CIR.0000000000001442. Online ahead of print.ABSTRACTThe United States is facing a growing health care affordability crisis. In 2024, national health expenditures totalled $5.3 trillion, or $15 474 per person, accounting for 18.0% of the U.S. economy. Spending o

D Dhruv S Kazi

Novel Truncating Variant c.1222DupC in RBM20 Causes Cardiomyopathy Consistent With Haploinsufficiency

Circ Genom Precis Med. 2026 Apr 30:e005471. doi: 10.1161/CIRCGEN.125.005471. Online ahead of print.ABSTRACTBACKGROUND: RBM20 (RNA binding motif protein 20) is a cardiac splicing factor responsible for the splicing of several cardiac genes such as titin (TTN), triadin (TRDN), ryanodine receptor 2 (RY

P Priyanka Pant

Late-Life Incident Stroke in the Atherosclerosis Risk in Communities Study: Cause and Prediction

Stroke. 2026 Apr 30. doi: 10.1161/STROKEAHA.125.054194. Online ahead of print.ABSTRACTBACKGROUND: As life expectancy rises, identifying causes and risk factors for incident acute ischemic stroke (AIS) among the oldest-old (≥80 years) is increasingly important. We examined whether the effect of age a

J Jing Wang

Associations of frailty with the incidence and progression trajectory of cardiometabolic-kidney multimorbidity: insights from multi-state modelling

J Glob Health. 2026 Apr 30;16:04133. doi: 10.7189/jogh.16.04133.ABSTRACTBACKGROUND: The American Heart Association recently introduced the cardiovascular-kidney-metabolic concept, but the impacts of frailty status on the disease trajectories remain unknown. We aimed to investigate the role of frailt

M Minghui Han

Association between physical activity and cardiovascular-kidney-metabolic syndrome in older Chinese adults: a nationwide, cross-sectional study

J Glob Health. 2026 Apr 30;16:04149. doi: 10.7189/jogh.16.04149.ABSTRACTBACKGROUND: Cardiovascular-kidney-metabolic (CKM) syndrome represents a new framework to address the non-communicable disease burden in ageing populations. However, evidence on the association between physical activity and the i

Q Qingmei Liu

A prospective, randomized, double-blind, placebo-controlled, multicenter study of thiamin plus folic acid in the treatment of cognitive impairment in patients undergoing maintenance hemodialysis

Ren Fail. 2026 Dec;48(1):2658981. doi: 10.1080/0886022X.2026.2658981. Epub 2026 Apr 30.ABSTRACTThis prospective, randomized, double-blind, placebo-controlled trial investigated the efficacy and safety of thiamin and folic acid for cognitive impairment in maintenance hemodialysis (MHD) patients. A to

K Kewei Xie

The importance of early intraoperative ultrasonography and the relationship between surgical technique and allograft function in patients with compartment syndrome following renal transplantation surgery

Turk J Med Sci. 2026 Jan 25;56(2):464-470. doi: 10.55730/1300-0144.6180. eCollection 2026.ABSTRACTBACKGROUND/AIM: In rare cases, patients undergoing renal transplantation (RT) may develop renal allograft compartment syndrome (RACS) if the renal volume is larger than the retroperitoneal space prepare

B Burak Yağdiran

Serum phosphoproteome alterations associated with cardiac troponin I levels in acute myocardial infarction

Turk J Med Sci. 2026 Jan 13;56(2):613-623. doi: 10.55730/1300-0144.6194. eCollection 2026.ABSTRACTBACKGROUND/AIM: Acute myocardial infarction (AMI) triggers systemic biochemical responses, including dynamic changes in the phosphorylation status of circulating proteins. However, the phosphoproteomic

M Merve Öztuğ

Effects of colchicine on SAH-induced vascular damage in an experimental subarachnoid hemorrhage model

Turk J Med Sci. 2025 Jul 26;56(2):597-607. doi: 10.55730/1300-0144.6192. eCollection 2026.ABSTRACTBACKGROUND/AIM: Subarachnoid hemorrhage (SAH) is a severe cerebrovascular condition associated with high morbidity and mortality. Inflammation and oxidative stress play critical roles in its pathophysio

E Emine Demir

Impact of two sedation protocols on cardiac electrophysiology during spinal anesthesia

Turk J Med Sci. 2026 Jan 19;56(2):479-488. doi: 10.55730/1300-0144.6182. eCollection 2026.ABSTRACTBACKGROUND/AIM: Perioperative factors such as anesthetic drugs, central blocks, surgical stress, pain, and anxiety can affect cardiac electrophysiology and increase the risk of arrhythmias. Arrhythmia s

S Selvinaz Durantaş

Analysis of CALR-mutated essential thrombocythemia as a distinct disease entity compared with JAK2 V617F-mutated and triple-negative patients

Turk J Med Sci. 2026 Feb 22;56(2):497-508. doi: 10.55730/1300-0144.6184. eCollection 2026.ABSTRACTBACKGROUND/AIM: Calreticulin (CALR) mutations in essential thrombocythemia (ET) are associated with younger age, higher platelet counts, and lower thrombosis rates. The present study analyzes the demogr

G Gökhan Sami Aydin

Preeclampsia as an early manifestation of cardiovascular-kidney-metabolic syndrome

No abstractFront Physiol. 2026 Apr 14;17:1796673. doi: 10.3389/fphys.2026.1796673. eCollection 2026.NO ABSTRACTPMID:42058974 | PMC:PMC13120892 | DOI:10.3389/fphys.2026.1796673

P Priscila Oliveira Barbosa

Clinical value of non-electrocardiogram-gated computed tomography angiography for planning transcatheter aortic valve implantation: A retrospective single-centre study

JRSM Cardiovasc Dis. 2026 Apr 24;15:20480040261445492. doi: 10.1177/20480040261445492. eCollection 2026 Jan-Dec.ABSTRACTPURPOSE: Computed tomography angiography (CTA) is a key component of preprocedural planning for transcatheter aortic valve implantation (TAVI). Although current guidelines recommen

S Said Sanoussi

Air Pollution Within the Public Health Exposome Framework: Impacts on Cardiovascular Health

Curr Epidemiol Rep. 2026;13(1):13. doi: 10.1007/s40471-026-00391-z. Epub 2026 Apr 27.ABSTRACTPURPOSE OF REVIEW: Ambient air pollution drives cardiovascular disease (CVD), yet single-pollutant models overlook how risk emerges within broader environmental and structural contexts. This review applies t

L Lucia D Juarez

Preliminary comparative evaluation of an immunofluorescence point-of-care system and central laboratory platforms for measuring cardiac biomarkers

Pract Lab Med. 2026 Apr 18;50:e00532. doi: 10.1016/j.plabm.2026.e00532. eCollection 2026 Jul.ABSTRACTBACKGROUND: Point-of-care testing (POCT) can accelerate clinical decision-making, but its analytical performance must be verified against central laboratory platforms before implementation. This stud

M Michela Salvatici