Impedimetric sensing of C-reactive protein using a novel molecularly imprinted polymer coupled with bismuth-enhanced cobalt ferrite nanocomposites for cardiovascular risk assessment

This study reports an approach of using a molecularly imprinted polymer (MIP) combined with Bi-doped cobalt ferrite (Bi(x)CoFe(2)O(4)) nanoparticles (NPs) for detecting C-reactive protein (CRP), a marker associated with cardiovascular diseases (CVDs). Sudden cardiac arrest is a growing concern in In

S Siddhima Singh

Role SGLT2 inhibitor therapy in patients with transthyretin cardiac amyloidosis: a GRADE assessed systematic review and meta-analysis

Acta Cardiol. 2025 Dec 5:1-9. doi: 10.1080/00015385.2025.2594908. Online ahead of print.ABSTRACTBACKGROUND: Transthyretin amyloid cardiomyopathy (ATTR-CM) patients continue to experience worsening heart failure despite therapy with disease modifying therapies (tafamidis, patisiran, etc.). Given the

A Ahmed Ali Khan

New insights into clinical strategies for acute coronary syndrome based on biomarker-driven multiomics research

Clin Exp Hypertens. 2025 Dec 31;47(1):2593619. doi: 10.1080/10641963.2025.2593619. Epub 2025 Dec 5.ABSTRACTWith rapid advancements in genomics, proteomics, and metabolomics researchers have gained significant insights into ACS (ACS) pathogenesis. Studies have revealed specific biomarkers linked to A

Z Zhixuan Zhao

Use of SGLT2 (Sodium-Glucose Cotransporter 2) Inhibitors in Pulmonary Hypertension

Circ Heart Fail. 2025 Dec 5:e013481. doi: 10.1161/CIRCHEARTFAILURE.125.013481. Online ahead of print.ABSTRACTInhibiting SGLT2 (sodium-glucose cotransporter 2) has recently transformed the medical care of patients with left heart disease. Right ventricular failure is a major predictor for patients su

B Benoit Aguado

Childhood Blood Pressure Predicts Longitudinal Decline in Vascular Function: The ExAMIN Youth SA Study

Hypertension. 2025 Dec 5. doi: 10.1161/HYPERTENSIONAHA.125.25888. Online ahead of print.ABSTRACTBACKGROUND: Elevated childhood blood pressure (BP) is a known predictor of future adult cardiovascular risk. We explored whether baseline BP predicted vascular health decline over time.METHODS: We include

C Chanelle Volschenk

Enhanced cardioprotective efficacy of Rosmarinus officinalis-loaded polydopamine nanoparticles for targeted therapy of myocardial infarction

J Biomater Sci Polym Ed. 2025 Dec 5:1-21. doi: 10.1080/09205063.2025.2590717. Online ahead of print.ABSTRACTMyocardial infarction (MI) is a predominant cause of mortality and heart failure in cardiovascular disorders. This article presents a novel polydopamine (PD) nanoparticles, tagged with cyclic

M Ming Zhang

Domain-specific knowledge on salt-related health risks and medical professional identity: Implications for cardi-ovascular prevention

Cardiol J. 2025 Dec 5. doi: 10.5603/cj.108977. Online ahead of print.ABSTRACTBACKGROUND: Excessive salt consumption is one of the most important and modifiable risk factors for cardiovascular disease (CVD). Despite general awareness of its cardiovascular impact, knowledge about other health conseque

S Stanisław Surma

Developing a LASSO Regression-Based Nomogram to Predict Outcomes in Abdominal Aortic Aneurysm Patients Post-Endovascular Aneurysm Repair

Clin Interv Aging. 2025 Nov 28;20:2241-2253. doi: 10.2147/CIA.S493841. eCollection 2025.ABSTRACTINTRODUCTION: This study aimed to develop a prognostic model to predict outcomes in patients undergoing endovascular aneurysm repair (EVAR) for abdominal aortic aneurysms (AAA).METHODS: 304 participants w

F Fengyi Yu

Evaluation of Carotid Intima-Media Thickness and Other Cardiovascular Risk Factors in Children with Chronic Kidney Disease

J Clin Pract Res. 2025 Oct 23;47(5):494-502. doi: 10.14744/cpr.2025.60232. eCollection 2025 Oct.ABSTRACTOBJECTIVE: The onset of chronic kidney disease during childhood substantially increases the risk of cardiovascular complications in adulthood among affected patients. In such patients, chronic dam

N Nadide Melike Sav

Decoding Immune Influence: A Mendelian Randomisation Study on Dilated Cardiomyopathy

CONCLUSION: These findings provide novel evidence supporting a causal role of elevated CD4^(+) Treg levels in DCM development and highlight the critical impact of immune regulation in its pathogenesis. Future studies are warranted to validate these associations and elucidate the underlying biologica

W Wei Gao

The Coronary Microcirculation Re-explored: Pathophysiological Insights and Clinical Implications

Eur Cardiol. 2025 Nov 8;20:e34. doi: 10.15420/ecr.2025.30. eCollection 2025.ABSTRACTCoronary microvascular dysfunction (CMD) is being increasingly recognised as a significant contributor to myocardial ischaemia, particularly in patients without obstructive coronary artery disease. This review explor

A Ahmed Elamin

Editorial: The role of autophagy in cardiovascular disease

No abstractFront Cell Dev Biol. 2025 Nov 19;13:1697218. doi: 10.3389/fcell.2025.1697218. eCollection 2025.NO ABSTRACTPMID:41347149 | PMC:PMC12673564 | DOI:10.3389/fcell.2025.1697218

Q Qinchun Duan

Inflammatory storm and metabolic disorders: unraveling heterogeneity in mortality risk for comorbid diabetes mellitus and heart failure via the C-reactive protein-triglyceride-glucose index

Front Endocrinol (Lausanne). 2025 Nov 19;16:1689238. doi: 10.3389/fendo.2025.1689238. eCollection 2025.ABSTRACTINTRODUCTION: Acute decompensated heart failure (ADHF), a critical cardiovascular emergency, is driven by a metabolic and inflammatory imbalance that serves as the central mechanism of dise

N Na Zhang

Effectiveness of PCSK9 inhibitors versus statins in type 2 diabetes and dyslipidemia: a propensity-matched study

Front Endocrinol (Lausanne). 2025 Nov 19;16:1709009. doi: 10.3389/fendo.2025.1709009. eCollection 2025.ABSTRACTBACKGROUND: Proprotein convertase subtilisin/kexin type 9 inhibitors (PCSK9is) exhibit promising lipid-lowering activity, but evidence regarding their effectiveness in real-world diabetic p

J Jheng-Yan Wu

Hypersensitive C-reactive protein-atherogenic index as a novel marker for metabolic dysfunction-associated steatotic liver disease in type 2 diabetes mellitus

Front Endocrinol (Lausanne). 2025 Nov 19;16:1721278. doi: 10.3389/fendo.2025.1721278. eCollection 2025.ABSTRACTBACKGROUND: Hypersensitive C-reactive protein-atherogenic index (CAI) may serve as a novel marker for metabolic dysfunction-associated steatotic liver disease (MASLD) in type 2 diabetes mel

W Wei Wang

Resistin in cardiac diseases: from molecular mechanisms to clinical implications

Front Endocrinol (Lausanne). 2025 Dec 3;16:1708332. doi: 10.3389/fendo.2025.1708332. eCollection 2025.ABSTRACTResistin, a cysteine-rich adipokine, exhibits significant species-specific divergence in its cellular origins and pathophysiological functions. In humans, it is primarily secreted by monocyt

Y Yicheng Ling

Assessment of myocardial structure and function in rheumatoid arthritis patients treated with biologics: tumor necrosis factor inhibitors and anti-interleukin-6 versus conventional disease-modifying drugs

Reumatologia. 2025 Nov 11;63(5):304-312. doi: 10.5114/reum/203546. eCollection 2025.ABSTRACTINTRODUCTION: Biologic treatments have demonstrated increasing benefits for cardiovascular health in patients with rheumatoid arthritis (RA), including reductions in myocardial infarction risk factors, athero

B Beata Dubiel-Braszczok

Metformin enhances alpelisib sensitivity in HER2+ breast cancer by suppressing cancer stemness and oncogenic signaling

Front Oncol. 2025 Nov 19;15:1631415. doi: 10.3389/fonc.2025.1631415. eCollection 2025.ABSTRACTINTRODUCTION: Alpelisib, a selective PI3Kα inhibitor that targets PIK3CA mutations, is approved for hormone receptor-positive, HER2-negative breast cancer. However, its therapeutic potential in HER2-positiv

Y Yujie Shi

Role of Macrophage Phagocytosis as Predictive Marker of the Prevalence of Coronary Heart Disease and Acute Coronary Syndromes

Cardiovasc Ther. 2025 Nov 26;2025:9927583. doi: 10.1155/cdr/9927583. eCollection 2025.ABSTRACTBACKGROUND: Atherosclerotic cardiovascular disease (ASCVD) pathogenesis is closely associated with macrophages. This study sought to explore the role of phagocytosis by monocyte-derived macrophages (MDMs) i

Y Yuming Wang

Apolipoprotein B in the Risk Assessment, Diagnosis, and Treatment of Cardiometabolic Diseases

Cardiol Cardiovasc Med. 2025;9(5):427-438. doi: 10.26502/fccm.92920466. Epub 2025 Sep 4.ABSTRACTApolipoprotein B (ApoB) has emerged as a central biomarker and mechanistic driver of atherosclerotic cardiovascular disease (ASCVD), outperforming traditional lipid metrics in both risk stratification and

S Shaan Patel

The Impact of Digital Health Interventions on Quality of Life Outcomes in Heart Failure Patients: A Systematic Review and Meta-Analysis

Cureus. 2025 Nov 2;17(11):e95964. doi: 10.7759/cureus.95964. eCollection 2025 Nov.ABSTRACTDespite routine management, heart failure (HF) patients often contend with a burdensome symptomatology negatively affecting their quality of life (QoL). The use of digital health interventions (DHIs) such as mo

U Uchenna Obonna

Recurrent Spontaneous Coronary Artery Dissection (SCAD) With a Family History of Cardiovascular Disease: A Case Report

Cureus. 2025 Nov 3;17(11):e96029. doi: 10.7759/cureus.96029. eCollection 2025 Nov.ABSTRACTSpontaneous coronary artery dissection (SCAD) is a rare cause of acute coronary syndrome and is often associated with fibromuscular dysplasia (FMD). We describe the case of a 55-year-old woman with a prior hist

C Carolina Suárez Burneo

A meta-synthesis of qualitative studies on cardiovascular disease patients' experiences using digital health tools

Front Public Health. 2025 Nov 10;13:1709562. doi: 10.3389/fpubh.2025.1709562. eCollection 2025.ABSTRACTOBJECTIVES: This review aims to provide deeper insights into the patient experience by synthesizing qualitative findings from studies on DHTs used in CVD care. Specifically, it seeks to answer the

Y Yuxuan Shao

Reactive oxygen species/hypoxia dual-responsive polymers combined with melatonin inhibited PANoptosis of retinal ganglion cells for acute glaucoma treatment

Theranostics. 2026 Jan 1;16(2):830-851. doi: 10.7150/thno.112836. eCollection 2026.ABSTRACTRationale: Acute glaucoma is triggered by sudden spikes in intraocular pressure, which induces retinal ischemia/reperfusion (RI/R), leading to hypoxia, oxidative stress, and ultimately PANoptosis in retinal ga

S Shuhan Meng