Learning curve of two-incision thoracoscopic double valve replacement: Cumulative sum analysis of postoperative outcomes and proficiency in 252 operations from a single high-volume center

Ther Adv Cardiovasc Dis. 2026 Jan-Dec;20:17539447261475835. doi: 10.1177/17539447261475835. Epub 2026 Aug 14.ABSTRACTBackgroundDespite the increasing adoption of minimally invasive approaches for valvular heart disease, the learning trajectory for complex thoracoscopic double valve replacement (DVR)

Q Qichen Xu

DWI-Positive Lesions in Patients With Acute Intracerebral Hemorrhage: Associations With Cerebral Small Vessel Disease and Clinical Outcome

Neurology. 2026 Sep 22;107(6):e218449. doi: 10.1212/WNL.0000000000218449. Epub 2026 Aug 14.ABSTRACTBACKGROUND AND OBJECTIVES: Diffusion-weighted imaging (DWI)-positive lesions are increasingly recognized as markers of cerebral small vessel disease (cSVD) in acute intracerebral hemorrhage (ICH), but

M Martina Locatelli

Integrative Multi-omics Analysis for Prioritization of Candidate Genes in Polycystic Ovary Syndrome

FASEB J. 2026 Aug 31;40(16):e72200. doi: 10.1096/fj.202601567R.ABSTRACTThe genetic architecture of polycystic ovary syndrome (PCOS) has not been fully elucidated. Translating genome-wide association study (GWAS) loci into functional effector genes represents a key challenge for elucidating disease m

R Ruiqi Guo

Magnesium Attenuates Renal Senescence and Fibrosis With Reduced DNA Damage Response and H3K4me3 Enrichment at the p16INK4a Promoter

Renal fibrosis is a final pathway leading to end-stage renal disease, with cellular senescence contributing to fibrosis and inflammation. Magnesium ions (Mg^(2+)) are implicated in DNA stabilization and epigenetic regulation. In this study, we hypothesized that Mg^(2+) ameliorates renal fibrosis in

M Makoto Matsubara

Association of modifiable behavioral risk factors with premature and all-cause mortality in patients with cardiovascular disease: A retrospective cohort study

Sci Prog. 2026 Jul-Sep;109(3):368504261479121. doi: 10.1177/00368504261479121. Epub 2026 Aug 14.ABSTRACTObjectiveThis study examined the separate and joint associations between modifiable behavioral risk factors (daily sitting time (DST), physical activity (PA) levels) and all-cause and premature mo

Y Yuqing Yuan

HSP27 regulates force-coordinated DDR1 condensate disassembly and liquid-to-gel phase transition

Sci Adv. 2026 Aug 14;12(33):eaec2282. doi: 10.1126/sciadv.aec2282. Epub 2026 Aug 14.ABSTRACTEndothelial cell (EC) mechanosensing is essential for vascular homeostasis and atherosclerosis development, though the influence of blood flow patterns on EC signaling is not fully understood. Discoidin domai

D Di Zhao

Insights from a digital health literacy coaching intervention for patients with hypertension in the emergency department: A cohort study

Health Informatics J. 2026 Jul-Sep;32(3):14604582261475495. doi: 10.1177/14604582261475495. Epub 2026 Aug 14.ABSTRACTObjectiveDigital health literacy (DHL), as part of the social determinants of health, affects health outcomes. To address the problem of poor DHL in under-served populations, we desig

C Colton Hood

LDL-C target attainment and treatment costs in high-risk and very-high-risk patients with or without bempedoic acid: A Spanish cohort simulation

PLoS One. 2026 Aug 14;21(8):e0353193. doi: 10.1371/journal.pone.0353193. eCollection 2026.ABSTRACTAchieving low-density lipoprotein cholesterol (LDL-C) targets remains challenging for Spanish patients at high (HR) or very-high (VHR) cardiovascular risk, despite treatment with statins and/or ezetimib

J Juan Cosin-Sales

Association between serum albumin and preoperative Deep Vein Thrombosis in patients aged 80 and over with intertrochanteric fracture: A retrospective observational study

PLoS One. 2026 Aug 14;21(8):e0345895. doi: 10.1371/journal.pone.0345895. eCollection 2026.ABSTRACTOBJECTIVE: The association between serum albumin level and preoperative deep vein thrombosis (DVT) in patients aged ≥ 80 years with intertrochanteric fractures remains unclear. This study aimed to exami

C Caizhen Chen

Sex differences in the effects of shift work-like schedules on gut microbiome and intestinal barrier in relation to stroke survival

PLoS One. 2026 Aug 14;21(8):e0355842. doi: 10.1371/journal.pone.0355842. eCollection 2026.ABSTRACTDisturbances of 24-hour or circadian rhythms imposed by everyday irregular work and/or social schedules have been linked to vascular disease, including ischemic stroke. Using an established shift work-l

E Ella Barnum

Association between gallstones and subclinical coronary atherosclerosis: An observational study with propensity score matching

PLoS One. 2026 Aug 14;21(8):e0356142. doi: 10.1371/journal.pone.0356142. eCollection 2026.ABSTRACTPrevious studies reporting an association between gallstones and coronary artery disease have not considered the types of coronary artery plaque. Additionally, the association between gallstones and sub

S Soyoung Kim

Predictors of Illness Acceptance Among Hypertensive Patients in Freetown: A Multivariate Analysis of Sociodemographic, Religiosity, and Quality of Life Factors

J Prim Care Community Health. 2026 Jan-Dec;17:21501319261479422. doi: 10.1177/21501319261479422. Epub 2026 Aug 14.ABSTRACTObjectivesTo determine the sociodemographic, religiosity, and quality of life (QoL) predictors of illness acceptance among hypertensive patients.MethodsThis cross-sectional study

A Ahmed Vandy

Body mass index predicts ventricular repolarisation in obese children: differential effects across obesity levels

Cardiovasc J Afr. 2026 Jul 31;37(3):282-292. doi: 10.5830/CVJA-2026-029. Epub 2026 Jul 31.ABSTRACTBACKGROUND: Childhood obesity is associated with cardiac electrical remodelling, yet the relationship between body mass index (BMI) and ventricular repolarisation (VR) heterogeneity remains incompletely

M Metin Karayakalı

ZIP1 Is a Critical DNA Damage-Responsive Zinc Transporter Induced by Bleomycin via the TNFα-NF-κB Pathway

FASEB J. 2026 Aug 31;40(16):e72193. doi: 10.1096/fj.202602997R.ABSTRACTZinc is an essential trace element that plays a significant role in DNA damage repair (DDR). Cells must maintain zinc homeostasis to effectively respond to DNA damage caused by various stressful stimuli. Members of the Zrt-, Irt-

Z Zichong Li

Contemporary Imaging Modalities for Transcatheter Interatrial Communication Closure: A Comparative Meta-Analysis of Intracardiac and Transesophageal Echocardiography

Echocardiography. 2026 Aug;43(8):e70598. doi: 10.1111/echo.70598.ABSTRACTBACKGROUND: Intracardiac echocardiography (ICE) is increasingly used to guide cardiovascular interventions. This study compared the performance of ICE with transesophageal echocardiography (TEE) in device closures of interatria

D Dyah Wulan Anggrahini

Analysis of adjudicated causes of death in a large cohort of Brazilian patients undergoing dialysis

J Nephrol. 2026 Aug 14:aajag152. doi: 10.1093/joneph/aajag152. Online ahead of print.ABSTRACTBACKGROUND: Patients with chronic kidney disease (CKD) undergoing dialysis have a high mortality risk. Cardiovascular and infectious events are the leading causes of death in this population; in Brazil, data

C Cristiane de Magalhães Rosa Ribeiro

Clinical Risk Assessment of Acute Intermediate-Risk Pulmonary Embolism Using Repeat Transthoracic Echocardiography

Echocardiography. 2026 Aug;43(8):e70595. doi: 10.1111/echo.70595.ABSTRACTBACKGROUND: Current risk stratification algorithms for intermediate-risk pulmonary embolism (PE) inadequately identify patients who may benefit from escalated care interventions (ECIs) beyond anticoagulation and do not incorpor

S Shervin Zoghi

Endomyocardial Biopsies in the Diagnostic Workup of Immune Checkpoint Inhibitor Associated Myocarditis

Curr Heart Fail Rep. 2026 Aug 14;23(1):41. doi: 10.1007/s11897-026-00775-8.ABSTRACTPURPOSE OF REVIEW: To identify the role of endomyocardial biopsy in the diagnosis, prognostication, and future understanding of mechanisms for immune checkpoint inhibitor myocarditis.RECENT FINDINGS: The use of endomy

K Keila C Ostos-Mendoza

Mechanistic Insights into Houttuynia cordata Thunb. as a Potential Therapeutic Strategy Targeting Metabolic Disorders in Preclinical Models

Curr Nutr Rep. 2026 Aug 14;15(1):68. doi: 10.1007/s13668-026-00791-z.ABSTRACTBACKGROUND: Metabolic syndrome comprises insulin resistance, obesity, hypertension, and dyslipidaemia, increasing the risk of diabetes and cardiovascular diseases. It is a major contributor to global mortality. Approximatel

M Manashi Karmakar

Precision Lipid Management in the Era of Biotechnology and Artificial Intelligence: From Gene Editing to Smart Drug Delivery

Ther Innov Regul Sci. 2026 Aug 14. doi: 10.1007/s43441-026-01033-8. Online ahead of print.ABSTRACTBACKGROUND: Hyperlipidemia is a major modifiable contributor to atherosclerotic cardiovascular disease (ASCVD). Despite statins as first-line therapy, residual cardiovascular risk, treatment intolerance

E Esra Palabiyik

Object size-dependent bias in aortic valve calcium quantification: polychromatic images vs virtual monochromatic images

Eur Radiol Exp. 2026 Aug 14;10(1):115. doi: 10.1186/s41747-026-00779-y.ABSTRACTOBJECTIVES: To compare aortic valve calcification (AVC) quantifications between polychromatic images (PI) and 70-keV virtual monochromatic images (VMI) obtained from photon-counting detector CT (PCD-CT), and to assess the

H Haruna Sagoh

ECMO for out of hospital refractory cardiac arrest in children: a retrospective multicenter analysis of a regional care program

Eur J Pediatr. 2026 Aug 14;185(9):666. doi: 10.1007/s00431-026-07303-9.ABSTRACTExtracorporeal membrane oxygenation (ECMO) during cardiopulmonary resuscitation (ECPR) is a lifesaving technology that has been widely described for in-hospital cardiac arrest in children with underlying cardiac disease.

J Julie Starck

MicroRNAs in dilated cardiomyopathy: from biomarkers to therapeutic targets

Mol Biol Rep. 2026 Aug 14;53(1):1407. doi: 10.1007/s11033-026-12573-5.ABSTRACTDilated cardiomyopathy (DCM) remains a leading cause of non-ischemic heart failure and sudden cardiac death, with substantial heterogeneity in clinical presentation and outcomes. Conventional diagnostic tools and circulati

A Abisha Vince Jeo V S

Adulting in the Current Era: Piloting an Individualized In-Person Congenital Heart Disease Transition Education Program

Pediatr Cardiol. 2026 Aug 14. doi: 10.1007/s00246-026-04423-9. Online ahead of print.ABSTRACTAdolescents with congenital heart disease (CHD) have varying degrees of readiness to transition to adulthood, including CHD knowledge, disease management skills, and engagement in the transition process. The

J John C Shabosky