A clinical case of a mixed variant (cardiomyopathy and polyneuropathy) of hereditary transthyretin amyloidosis

Ter Arkh. 2026 May 2;98(4):251-258. doi: 10.26442/00403660.2026.04.203572.ABSTRACTAmyloidosis associated with mutations in the transthyretin gene is the most common form of hereditary systemic amyloidosis. The onset and phenotype of the disease depend on the type of mutation, but the peripheral nerv

D D P Golubovskaya

Cardiorenal syndrome in an 85-year-old patient with neurofibromatosis. Case report

Ter Arkh. 2026 May 2;98(4):243-250. doi: 10.26442/00403660.2026.04.203586.ABSTRACTNeurofibromatosis (NF) is a hereditary disease characterized by the formation and growth of benign tumors of neuroectodermal origin. There are three main nosological forms: NF1, NF2, NF3. It is believed that the diseas

E E V Reznik

The role and place of rivaroxaban in modern anticoagulant therapy of patients with atrial fibrillation. A review

Ter Arkh. 2026 May 2;98(4):237-242. doi: 10.26442/00403660.2026.04.203513.ABSTRACTAtrial fibrillation is the most common type of arrhythmia, the "epidemic of the 21st century" and the leading cause of cardioembolic ischemic stroke. Clinical guidelines recommend direct oral anticoagulants as first-li

S S K Zyryanov

Clinical and diagnostic significance of extracellular volume in different periods of left ventricular myocardial infarction. A review

Ter Arkh. 2026 May 2;98(4):231-236. doi: 10.26442/00403660.2026.04.203577.ABSTRACTThis review examines the pathophysiological processes affecting the Extracellular Volume (ECV) in both the acute and chronic phases of myocardial infarction. It discusses how the constellation of acute myocardial injur

V V E Oleynikov

Interleukin-1 activity regulators in acute decompensated heart failure: dependence on obesity degree

Ter Arkh. 2026 May 2;98(4):226-230. doi: 10.26442/00403660.2026.04.203576.ABSTRACTAIM: To assess the circulating levels of IL-1 and its activity regulators, IL-1Ra and IL-1R2, in patients with acute decompensated heart failure (ADHF) depending on body mass index (BMI).MATERIALS AND METHODS: The stud

A A A Korotaeva

A "risk score scale" based on computed tomography angiography of the coronary arteries to assess the risk of cardiovascular events in the first year after acute coronary syndrome

Ter Arkh. 2026 May 2;98(4):202-208. doi: 10.26442/00403660.2026.04.203573.ABSTRACTAIM: Development of a "Risk Score Scale" (RSS) to assess the risk of Major Adverse Cardiovascular Events (MACE) based on computed tomographic angiography (CTА) of the coronary arteries in patients with acute coronary s

I I N Merkulova

FGL2-HDAC11 Drives Immunothrombosis via NETs-Mediated Endothelial Capillarization in MASLD Fibrosis

Adv Sci (Weinh). 2026 May 10:e22985. doi: 10.1002/advs.202522985. Online ahead of print.ABSTRACTMetabolic dysfunction-associated steatotic liver disease (MASLD) is frequently accompanied by hepatic fibrosis and systemic cardiovascular complications; however, the mechanistic interplay between coagula

X Xitang Li

G3BP1 Succinylation at K413 is Critical for Cardiac Function by Modulating PI3K-AKT-mTOR Signal Axis

Adv Sci (Weinh). 2026 May 10:e19856. doi: 10.1002/advs.202519856. Online ahead of print.ABSTRACTG3BP1, GTPase activating protein (SH3 domain) binding protein 1, is a core component of stress granules. Homozygous null mutations in the G3bp1 gene result in embryonic lethality, underscoring its essenti

Y Yuan Zhang

Correlation of C1q/Tumor Necrosis Factor-Related Protein 1 with Left Ventricular Hypertrophy in Essential Hypertension Patients

Blood Press. 2026 May 10:1-15. doi: 10.1080/08037051.2026.2670144. Online ahead of print.ABSTRACTBACKGROUND: Left ventricular hypertrophy (LVH) is a critical complication of hypertension that correlates with increased morbimortality. Its pathophysiology is complex and multifaceted likely involving v

S Shuya Tian

Culture-Negative Infective Endocarditis Presenting as ANCA-Positive Glomerulonephritis

Am J Case Rep. 2026 May 10;27:e952252. doi: 10.12659/AJCR.952252.ABSTRACTBACKGROUND Infective endocarditis is challenging to diagnose when blood cultures are negative, and its symptoms are nonspecific. Bartonella species are fastidious intracellular bacteria that can cause culture-negative endocardi

M Mohammad Eshaq Kyhan

Incident cancer in heart failure, myocardial infarction or both: a report from a global federated research network

Eur J Heart Fail. 2026 May 10:xuag061. doi: 10.1093/ejhf/xuag061. Online ahead of print.ABSTRACTAIMS: Heart failure (HF) and acute myocardial infarction (AMI) may contribute to cancer development through shared and disease-related pathophysiological pathways. We investigated the mid-term risk of inc

M Massimiliano Camilli

Prevalence and Predictors of High Inflammatory Risk in Heart Failure Subtypes: Findings From the Global POSEIDON Study

Eur J Heart Fail. 2026 May 10:xuag155. doi: 10.1093/ejhf/xuag155. Online ahead of print.ABSTRACTAIMS: Inflammation contributes to the pathophysiology of heart failure (HF), yet the global prevalence of elevated high sensitivity C-reactive protein (hsCRP) in patients with HF across the ejection fract

C Carolyn S P Lam

The E3 Ubiquitin Ligase RNF123 Mediates Pathological Cardiac Hypertrophy by Ubiquitinating PRDX1 and Upregulating Oxidative Stress in Cardiomyocytes

Acta Physiol (Oxf). 2026 Jun;242(6):e70244. doi: 10.1111/apha.70244.ABSTRACTBACKGROUND: Pathological cardiac hypertrophy is a key risk factor for heart failure (HF). Illustrating the pathogenesis of cardiac hypertrophy may contribute to the treatment of HF. Studies have emphasized that protein ubiqu

Q Qinyan Wang

Digoxin in Patients With Symptomatic Rheumatic Heart Disease: A Randomized Clinical Trial

JAMA. 2026 May 10. doi: 10.1001/jama.2026.7335. Online ahead of print.ABSTRACTIMPORTANCE: Heart failure is the most common cause of death in patients with rheumatic heart disease. The efficacy and safety of digoxin in this population are not known.OBJECTIVE: To determine if digoxin, compared with pl

G Ganesan Karthikeyan

Ziltivekimab in heart failure with preserved and mildly reduced ejection fraction: rationale and design of the ATHENA and HERMES trials

Eur J Heart Fail. 2026 May 10:xuag153. doi: 10.1093/ejhf/xuag153. Online ahead of print.ABSTRACTBACKGROUND: For decades inflammation has been postulated to play a key pathophysiological role in heart failure (HF), particularly in HF with preserved ejection fraction (HFpEF). Previous attempts to targ

G Guiomar Mendieta

Association of Neutrophil Percentage-To-Albumin Ratio With All-Cause and Cardiovascular Mortality in Chronic Kidney Disease

Inquiry. 2026 Jan-Dec;63:1. doi: 10.1177/00469580261450864. Epub 2026 May 10.ABSTRACTIntroductionThis research sought to understand the relationship of the neutrophil percentage-to-albumin ratio (NPAR) and mortality from cardiovascular (CVD) and all causes in populations with CKD.Methods7,553 CKD pa

Y Yingying Wu

Safety and Feasibility of the eLymTM System for Interstitial Decongestion in Acute Decompensated Heart Failure: Primary results of the DELTA-HF trial

Eur J Heart Fail. 2026 May 10:xuag157. doi: 10.1093/ejhf/xuag157. Online ahead of print.ABSTRACTBACKGROUND: Persistent congestion at discharge is associated with worse outcomes in acute decompensated heart failure (ADHF), with impaired lymphatic function contributing to difficult-to-target tissue an

J Jorge Nuche

Short- and Long-Term Mortality in Patients Hospitalized for Dyspnoea with Acute Heart Failure, Respiratory Infection, or Both: Insights from the PARADISE Cohort

Eur J Heart Fail. 2026 May 10:xuag160. doi: 10.1093/ejhf/xuag160. Online ahead of print.ABSTRACTBACKGROUND: Acute heart failure (AHF) and respiratory infection (RI) frequently coexist, with the latter commonly regarded as a trigger of AHF decompensation. However, the independent and combined prognos

S Stefano Coiro

Clinical characteristics and vascular involvement of Takayasu arteritis versus Kawasaki disease in infants and young children

Pediatr Rheumatol Online J. 2026 May 9. doi: 10.1186/s12969-026-01222-7. Online ahead of print.ABSTRACTBACKGROUND: Childhood-onset Takayasu arteritis (c-TAK) in infants and young children often presents with systemic inflammation rather than ischemic symptoms, and its clinical features overlap with

C Congying Wang

The impact of war on Primary Health Care in Ukraine: a cross-sectional survey and qualitative interviews with service providers

BMC Health Serv Res. 2026 May 9. doi: 10.1186/s12913-026-14555-6. Online ahead of print.ABSTRACTBACKGROUND: Primary Health Care (PHC) is vital to supporting emergency preparedness and health care resilience. There is limited evidence of the impact of crises on PHC services and financing. We aimed to

A Adrianna Murphy

High-dose quadrivalent influenza vaccine in older adults with or without cardiovascular risk: a meta-analysis of randomized trials on 511,890 participants

Immun Ageing. 2026 May 9. doi: 10.1186/s12979-026-00571-x. Online ahead of print.ABSTRACTBACKGROUND: Older adults remain highly vulnerable to serious influenza-related complications despite routine vaccination. Whether high-dose quadrivalent influenza vaccine (HD-QIV) offers greater protection than

M Mohamed S Elgendy

Real-world prevalence and outcome of elevated right ventricular systolic pressure in myelofibrosis

Cardiooncology. 2026 May 9. doi: 10.1186/s40959-026-00474-2. Online ahead of print.ABSTRACTBACKGROUND: Myelofibrosis (MF) is a subgroup of Philadelphia chromosome-negative myeloproliferative neoplasms that are associated with an increased risk of cardiovascular disease, including pulmonary hypertens

A Alexis Behne Sharma

Multi-omics uncovers the pleiotropic genetic mechanisms linking MASLD and cardiometabolic syndromes

Cardiovasc Diabetol. 2026 May 9. doi: 10.1186/s12933-026-03180-6. Online ahead of print.ABSTRACTBACKGROUND: Metabolic dysfunction-associated steatotic liver disease (MASLD) and cardiovascular-kidney-metabolic (CKM) syndrome are interrelated conditions with shared pathophysiological features; however

K Kangjia Yin

Lifestyle front offices in dutch hospitals: a cross-sectional survey on similarities, differences and future needs

BMC Health Serv Res. 2026 May 9. doi: 10.1186/s12913-026-14506-1. Online ahead of print.ABSTRACTBACKGROUND: Since 2019, Dutch hospitals have been developing approaches aiming to bridge the gap between hospital care and community-based lifestyle support. This has led to the introduction of the so cal

F Florien Ham