Heart failure with reduced ejection fraction: A systematic review of clinical practice guidelines and recommendations

Eur Heart J Qual Care Clin Outcomes. 2026 Mar 4:qcag029. doi: 10.1093/ehjqcco/qcag029. Online ahead of print.ABSTRACTHeart failure with reduced ejection fraction (HFrEF) accounts for over half of heart failure cases and its management is directed by international clinical practice guidelines. To eva

S Shayan Datta

Urolithin A mitigates doxorubicin-induced myocardial injury via suppression of ROS-driven apoptotic signaling

Histol Histopathol. 2026 Mar 4:25054. doi: 10.14670/HH-25-054. Online ahead of print.ABSTRACTBACKGROUND: Doxorubicin (DOX), as a broad-spectrum antitumor drug, achieved great success in the clinic. Nevertheless, severe adverse effects, in particular cardiac toxicity, significantly restrict its clini

W Wei Song

Interplay of Age and Sex With Clinic and Ambulatory Blood Pressure and Mortality

Hypertension. 2026 Mar 4. doi: 10.1161/HYPERTENSIONAHA.125.26084. Online ahead of print.ABSTRACTBACKGROUND: To explore associations of clinic and 24-hour ambulatory blood pressure (BP) monitoring (ABPM) with cardiovascular death (CVD), parameters were modeled for age and sex in this large cohort in

M Michael Böhm

Cold-Induced Hypertension as Life-Environment Disease in Winter: Focus on Data From Japan

Hypertension. 2026 Mar 4. doi: 10.1161/HYPERTENSIONAHA.125.26518. Online ahead of print.ABSTRACTAn increase in the rate of cardiovascular events (eg, myocardial infarction, stroke, heart failure) during the winter season has been reported worldwide, including Japan. As 1 contributor to the increase

K Kazuomi Kario

Contemporary Prevalence and Treatment Patterns Among US Adults With Apparent Treatment-Resistant Hypertension

Hypertension. 2026 Mar 4. doi: 10.1161/HYPERTENSIONAHA.125.25659. Online ahead of print.ABSTRACTBACKGROUND: Resistant hypertension is associated with adverse cardiovascular outcomes and mortality. In the past decade, management guidelines have shifted to target lower blood pressures (BP). Current pr

W William B Earle

N-cadherin Adhesive Interactions Mechanically Modulate Phenotype of Pancreatic Stellate Cells via YAP-dependent Mechanosensing

Small Methods. 2026 Mar 4:e01659. doi: 10.1002/smtd.202501659. Online ahead of print.ABSTRACTPancreatic ductal adenocarcinoma (PDAC) exhibits a dense desmoplastic stroma primarily composed of cancer-associated fibroblasts (CAFs), which largely originate from pancreatic stellate cells (PSCs). Upon ac

S Simei Zhang

The Pulmonary Hypertension Global Patient Survey: Understanding the Invisible Burden of Paediatric Pulmonary Hypertension

Pulm Circ. 2026 Mar 2;16(1):e70269. doi: 10.1002/pul2.70269. eCollection 2026 Jan.ABSTRACTThe Pulmonary Hypertension Global Patient Survey (PH GPS) provides the first international examination of experiences among children with pulmonary hypertension (PH) and their caregivers. Through an online surv

S Sadia Quyam

Successful treatment of low-flow-low-gradient aortic stenosis and complex coronary artery disease in a patient with severely depressed left-ventricular function by protected percutaneous coronary intervention and transfemoral transcatheter aortic valve replacement via Y-graft vascular prosthesis: a case report

Eur Heart J Case Rep. 2026 Jan 24;10(3):ytag035. doi: 10.1093/ehjcr/ytag035. eCollection 2026 Mar.ABSTRACTINTRODUCTION: Low-flow, low-gradient aortic stenosis (LFLG AS) is a subset of aortic stenosis associated with a poor prognosis and high operative risk, particularly in the presence of concomitan

Y Yusuf Nejahsie

Phytochemical Composition and Therapeutic Potential of Ludwigia adscendens: A Narrative Review

ScientificWorldJournal. 2026 Mar 1;2026:5359686. doi: 10.1155/tswj/5359686. eCollection 2026.ABSTRACTLudwigia adscendens subsp. diffusa, an aquatic plant with an extended tradition of use in conventional healthcare, has received growing recognition for its variety of bioactive compounds. Numerous co

T Tasnia Mahmud Easha

Aconitine outperforms mesaconitine and hypaconitine in triggering excessive mitophagy via lysosomal two-pore channels disruption in SH-SY5Y cells and zebrafish

Toxicol Res (Camb). 2026 Feb 27;15(1):tfag008. doi: 10.1093/toxres/tfag008. eCollection 2026 Feb.ABSTRACTThe genus Aconitum L. is widely used in the treatment of rheumatoid arthritis, tumors, and cardiovascular diseases due to its prominent pharmacological properties. However, increasing scientific

H Han Feng

Association between the systemic inflammation response index and the prognosis of patients with myocardial infarction: a systematic review and meta-analysis

Front Cardiovasc Med. 2026 Feb 16;13:1755442. doi: 10.3389/fcvm.2026.1755442. eCollection 2026.ABSTRACTBACKGROUND: The systemic inflammation response index (SIRI), a novel biomarker integrating neutrophil, monocyte, and lymphocyte counts, has been implicated in cardiovascular disease prognosis. This

Y Yedan Wu

Case Report: Local anesthetic systemic toxicity during regional anesthesia in a patient with rheumatoid arthritis

Front Med (Lausanne). 2026 Feb 16;13:1758548. doi: 10.3389/fmed.2026.1758548. eCollection 2026.ABSTRACTBACKGROUND: Local anesthetic systemic toxicity (LAST) is a rare yet potentially life-threatening complication that requires prompt recognition and management. This condition commonly presents with

M Misa Baic

Carotid Endarterectomy in the Era of Stenting and Optimal Medical Therapy

Cureus. 2026 Jan 31;18(1):e102683. doi: 10.7759/cureus.102683. eCollection 2026 Jan.ABSTRACTCardiovascular events, including stroke and acute myocardial infarction (AMI), remain the leading causes of death worldwide. This study aimed to review the scientific literature evaluating carotid endarterect

Í Ítalo Eugênio Souza Gadelha de Abreu

Risk Factor Control in a Portuguese Vascular Risk Clinic: A 16-Month Retrospective Cohort Study

Cureus. 2026 Jan 31;18(1):e102735. doi: 10.7759/cureus.102735. eCollection 2026 Jan.ABSTRACTBackground Cardiovascular diseases (CVDs) are the leading cause of morbidity and mortality worldwide and in Portugal. Stroke remains one of the principal causes of death in Portugal, increasing the urgency of

C Cristiano Gante

Diabetes, Protein Misfolding, and Heat Stress: Molecular Insights and Translational Perspectives

TH Open. 2026 Feb 9;10:a27905251. doi: 10.1055/a-2790-5251. eCollection 2026.ABSTRACTDiabetes mellitus (DM), particularly type 1 (T1D) and type 2 (T2D), is a growing global health burden with complex pathophysiology extending beyond glucose dysregulation. Both forms of diabetes involve cellular stre

M M Marc Abreu

Severe Mitral Stenosis in Term Pregnancy Presenting During Labor in a Resource-Limited Setting: A Case Report from Borama, Awdal Region of Somalia

Int Med Case Rep J. 2026 Feb 26;19:564292. doi: 10.2147/IMCRJ.S564292. eCollection 2026.ABSTRACTBACKGROUND: Mitral stenosis (MS), primarily from rheumatic heart disease (RHD), is a significant cause of maternal morbidity and mortality, especially in low- and middle-income countries (LMICs). Pregnanc

A Abdirahman Mohamed Jama

The distribution of incidence rates of cardiovascular diseases in the elderly and the relationship between dietary patterns and cardiovascular risk

PeerJ. 2026 Feb 27;14:e20768. doi: 10.7717/peerj.20768. eCollection 2026.ABSTRACTBACKGROUND: Cardiovascular diseases (CVD) were leading causes of morbidity and mortality in the elderly. This study investigates the distribution of CVD incidence among older adults and examines the relationship between

Q Qi Yang

Clinical, social, molecular, and genetic predictors of cognitive resilience in long-living adults without dementia

Front Dement. 2026 Feb 16;4:1699695. doi: 10.3389/frdem.2025.1699695. eCollection 2025.ABSTRACTBACKGROUND: Long-living adults often maintain cognitive function despite neuropathological changes, which is often attributed to cognitive resilience (CR)-a combined effect of cognitive and cerebral reserv

E Ekaterina Spektor

Cardiovascular risk factor changes associated with six-year circuit training in older adults: a retrospective cohort analysis

Front Aging. 2026 Feb 16;7:1728121. doi: 10.3389/fragi.2026.1728121. eCollection 2026.ABSTRACTBACKGROUND: Physical exercise can significantly impact chronic disease prevention and health promotion in older adults. This retrospective cohort study evaluated the association between participation in a m

M Marcelo Pereira de Lima

Sex-based multiomics analysis uncovers metabolic and molecular mediators linking MASH and atherosclerosis

JHEP Rep. 2025 Dec 2;8(3):101703. doi: 10.1016/j.jhepr.2025.101703. eCollection 2026 Mar.ABSTRACTBACKGROUND & AIMS: Atherosclerotic cardiovascular disease (ASCVD) is the leading cause of death in patients with metabolic dysfunction-associated steatohepatitis (MASH). No therapy targets both diseases

S Sandeep Das

Exploring the role of microRNA-155 as a biomarker and regulatory modulator of target genes in metabolic syndrome

SAGE Open Med. 2026 Feb 27;14:20503121261416802. doi: 10.1177/20503121261416802. eCollection 2026.ABSTRACTCentral obesity is one of the defining features of metabolic syndrome (MetS). MetS comprises a cluster of metabolic disturbances including insulin resistance (IR), hypertension, and altered gluc

P Priyanka Murundi Panchakshari

Evaluating the association between oral microbiota and cardiovascular diseases: evidence from Mendelian randomization analysis

J Geriatr Cardiol. 2026 Jan 28;23(1):36-44. doi: 10.26599/1671-5411.2026.01.001.ABSTRACTBACKGROUND: Recent studies have suggested a potential role of the oral microbiome in the development of cardiovascular diseases. This study aims to investigate the association between oral microbiota and cardiova

S Si-Da Qin

From ancient herb to modern miracle: an in-depth analysis of the cardioprotective effects of artemisinin and its derivatives

J Geriatr Cardiol. 2026 Jan 28;23(1):45-64. doi: 10.26599/1671-5411.2026.01.007.ABSTRACTSignificant progress has been recently made in studying artemisinin and its derivatives for treating cardiovascular diseases, making this area a prominent research focus. Artemisinin, discovered with great acclai

H Hao-Shuang Li

CT-derived fractional flow reserve combined with atherosclerotic extent to determine long-term outcomes in diabetic patients with coronary artery disease

J Geriatr Cardiol. 2026 Jan 28;23(1):27-35. doi: 10.26599/1671-5411.2026.01.008.ABSTRACTBACKGROUND: There is still limited data on predictive value of coronary computed tomography angiography (CCTA)-derived fractional flow reserve (CT-FFR) for long term outcomes. We examined the long-term prognostic

Z Zhi-Qiang Wang