Ren Fail. 2026 Dec;48(1):2656561. doi: 10.1080/0886022X.2026.2656561. Epub 2026 Apr 29.ABSTRACTEnd-stage kidney disease (ESKD) patients receiving dialysis bear a heavy burden of cardiovascular disease (CVD), the leading cause of mortality. Mineralocorticoid receptor antagonists (MRAs) have cardiovas
Compr Physiol. 2026 Jun;16(3):e70159. doi: 10.1002/cph4.70159.ABSTRACTCardiovascular diseases remain the leading global cause of morbidity and mortality, with notable sex-specific differences in prevalence and outcomes. Increasing evidence indicates that β-adrenergic receptors (β-AR) play a central
Mol Cell Pediatr. 2026 Apr 30;13(1):24. doi: 10.1186/s40348-026-00236-1.ABSTRACTBACKGROUND: Although 22q11.2 deletion syndrome (22q11.2DS) is one of the most common microdeletion syndromes, a substantial proportion of patients with clinically suspected 22q11.2DS (clin22q11.2) remain without a defini
Drugs Aging. 2026 Apr 29. doi: 10.1007/s40266-026-01297-7. Online ahead of print.ABSTRACTBACKGROUND: Individuals at high risk of cardiovascular disease (CVD) often require multiple concurrent medications, resulting in polypharmacy. Although necessary for disease management, polypharmacy may increase
Eye (Lond). 2026 Apr 29. doi: 10.1038/s41433-026-04479-0. Online ahead of print.ABSTRACTBACKGROUND: It is unknown if ocular migraine patients have an increased risk of cerebrovascular disease. This study aimed to determine if cerebrovascular and cardiovascular events were elevated among those with o
Sci Rep. 2026 Apr 29. doi: 10.1038/s41598-026-51049-1. Online ahead of print.ABSTRACTThe issue of younger onset coronary heart disease (CHD) is becoming increasingly prominent. Percutaneous coronary intervention (PCI) has proven to be an effective treatment for CHD, significantly reducing mortality
Cardiol Ther. 2026 Apr 29. doi: 10.1007/s40119-026-00447-7. Online ahead of print.ABSTRACTINTRODUCTION: Stress-test echocardiography with speckle tracking modality (STM) is sensitive to detect myocardial ischemia. Data on trimetazidine (TMZ) therapy's effectiveness on myocardial ischemia and contrac
Sci Rep. 2026 Apr 29. doi: 10.1038/s41598-026-50362-z. Online ahead of print.ABSTRACTAngiopoietin-like 8 (ANGPTL8) is a calorically responsive regulator of lipoprotein lipase (LPL). It does this by forming complexes with ANGPTL3 or ANGPTL4 that either inhibit LPL in oxidative tissues or preserve LPL
Int Urol Nephrol. 2026 Apr 29. doi: 10.1007/s11255-026-05162-9. Online ahead of print.ABSTRACTBACKGROUND: Post-transplant hypertension is common in kidney transplant recipients and contributes to cardiovascular risk and allograft dysfunction. Most available data come from studies where the primary i
J Hum Hypertens. 2026 Apr 29. doi: 10.1038/s41371-026-01150-9. Online ahead of print.ABSTRACTHypertension and diabetes commonly coexist, sharing mechanisms such as insulin resistance, obesity, and endothelial dysfunction, which together amplify cardiovascular, renal, and cerebrovascular risk. This d
Sci Rep. 2026 Apr 29. doi: 10.1038/s41598-026-50044-w. Online ahead of print.ABSTRACTAdolescence represents a pivotal period for the development of early diabetes-related vascular complications, primarily driven by chronic hyperglycemia and associated metabolic disturbances. Metabolomics provides a
Expert Rev Cardiovasc Ther. 2026 Apr 29. doi: 10.1080/14779072.2026.2665194. Online ahead of print.ABSTRACTBACKGROUND: Despite statin therapy, cardiovascular disease remains a leading cause of mortality. CSL112 enhances HDL function and reverse cholesterol transport, offering a novel strategy for at
Zhonghua Kou Qiang Yi Xue Za Zhi. 2026 Apr 30;61(5):655-660. doi: 10.3760/cma.j.cn112144-20260131-00073. Online ahead of print.ABSTRACTObjective: To investigate the disease types, clinical characteristics, and emergency manage ment measures for critical cases in the oral emergency department, and to
Ren Fail. 2026 Dec;48(1):2654347. doi: 10.1080/0886022X.2026.2654347. Epub 2026 Apr 29.ABSTRACTThis study evaluated the long-term outcomes of interventional therapy for transplant renal artery stenosis (TRAS). A total of 30 TRAS patients who underwent interventional treatment between February 2017 a
J Matern Fetal Neonatal Med. 2026 Dec;39(1):2661436. doi: 10.1080/14767058.2026.2661436. Epub 2026 Apr 29.ABSTRACTOBJECTIVE: The optimal interpregnancy interval (IPI) for preventing hypertensive disorders of pregnancy (HDP) remains unclear, and whether this association is modified by maternal baseli
J Formos Med Assoc. 2026 Apr 28:S0929-6646(26)00449-3. doi: 10.1016/j.jfma.2026.04.111. Online ahead of print.ABSTRACTStatins are the cornerstone of lipid-lowering therapy for the prevention of atherosclerotic cardiovascular disease (ASCVD); however, many patients are unable to achieve guideline-rec
J Int Med Res. 2026 Apr;54(4):3000605261443913. doi: 10.1177/03000605261443913. Epub 2026 Apr 29.ABSTRACTObjectiveMetabolic syndrome increases the risk of cardiovascular diseases and diabetes. This study examined the associations of body mass index and the appendicular lean mass-to-body weight ratio
J Int Med Res. 2026 Apr;54(4):3000605261443080. doi: 10.1177/03000605261443080. Epub 2026 Apr 29.ABSTRACTObjectiveThis study aimed to assess the performance of time to maximum concentration (Tmax) using computed tomography perfusion for predicting stroke recurrence in patients with symptomatic non-a
BMJ Case Rep. 2026 Apr 29;19(4):e270893. doi: 10.1136/bcr-2025-270893.ABSTRACTArthroscopic shoulder surgery is generally associated with a low complication rate. While complications such as neurological injury, stiffness and iatrogenic damage are relatively well recognised, the occurrence of deep ve
BMJ Case Rep. 2026 Apr 29;19(4):e272910. doi: 10.1136/bcr-2026-272910.ABSTRACTDeficiency of adenosine deaminase 2 (DADA2) is a rare monogenic autoinflammatory vasculopathy characterised by systemic vasculitis, immune dysregulation and haematological abnormalities. We report a man in his 30s who pres
BMJ Case Rep. 2026 Apr 29;19(4):e273252. doi: 10.1136/bcr-2026-273252.ABSTRACTPregnancy in women with autosomal dominant polycystic kidney disease (ADPKD) complicated by significant cardiovascular disease is high risk. We report a multiparous woman in her late 30s with ADPKD, chronic hypertension an
BMJ Open Respir Res. 2026 Apr 29;13(1):e004079. doi: 10.1136/bmjresp-2025-004079.ABSTRACTINTRODUCTION: Acute exacerbation of chronic obstructive pulmonary disease (AECOPD) may cause stress-induced transient acute cardiac dysfunction through myocardial stunning, in the form of exacerbation-triggered
BMJ Open Respir Res. 2026 Apr 29;13(1):e004016. doi: 10.1136/bmjresp-2025-004016.ABSTRACTBACKGROUND: Acute exacerbations (AEs) drive disease progression and healthcare burden in chronic obstructive pulmonary disease (COPD). Although prior AE history is the strongest predictor of future events, it ca
Circ J. 2026 Apr 29. doi: 10.1253/circj.CJ-25-1183. Online ahead of print.ABSTRACTBACKGROUND: Mac-2 binding protein glycosylation isomer (M2BPGi) is a validated biomarker for liver fibrosis in chronic liver disease. We investigated the clinical significance of serum M2BPGi concentrations in patients
