Specific serotonin receptor antagonist reduces murine calcific atherosclerosis

Atherosclerosis. 2026 Jan 27;414:120649. doi: 10.1016/j.atherosclerosis.2026.120649. Online ahead of print.ABSTRACTHigh levels of peripheral serotonin, produced in the gut, are associated with increased cardiovascular disease risk and bone loss. We previously found that vascular smooth muscle and va

A Andy Hon

Silencing CCL5 suppresses ferroptosis to alleviate calcific aortic valve disease through chemokine pathway inhibition

Atherosclerosis. 2026 Jan 16;414:120640. doi: 10.1016/j.atherosclerosis.2026.120640. Online ahead of print.ABSTRACTBACKGROUND: Calcific aortic valve disease (CAVD) involves pathological mineralization, but the roles of chemokine signaling and ferroptosis remain unclear. This study investigated the r

H Hongjin Zhang

The role of coronary artery calcification in metal-related cardiovascular disease

Environ Int. 2026 Jan 21;208:110095. doi: 10.1016/j.envint.2026.110095. Online ahead of print.ABSTRACTMetals are associated with cardiovascular disease (CVD), but the underlying pathways remain largely unclear. We evaluated the potential intermediate role of coronary artery calcification (CAC) traje

A Arce Domingo-Relloso

"Comprehensive multi-omics of age-respective plasma and matrix-bound extracellular vesicles identifies anti-fibrotic miRNAs validated on a heart-on-a-chip"

Biomaterials. 2026 Jan 29;330:124031. doi: 10.1016/j.biomaterials.2026.124031. Online ahead of print.ABSTRACTAging is a major risk factor for cardiovascular disease, the leading cause of death worldwide, and numerous other diseases, but the mechanisms of these aging-related effects remain elusive. R

G George Ronan

Brain-computer interfaces in poststroke rehabilitation: a meta-analysis of randomized clinical trials

Neurosurg Focus. 2026 Feb 1;60(2):E7. doi: 10.3171/2025.11.FOCUS25913.ABSTRACTOBJECTIVE: Stroke is a leading cause of long-term disability, with conventional rehabilitation often failing to achieve substantial motor recovery, particularly in patients with severe paresis or in chronic stages. Brain-c

A Ali Mortezaei

Development of a novel clinical prediction model for musculoskeletal chest pain in the emergency department

Orv Hetil. 2026 Feb 1;167(5):180-187. doi: 10.1556/650.2026.33484. Print 2026 Feb 1.ABSTRACTINTRODUCTION: The diagnostic work-up of patients presenting to the emergency department with chest pain remains a major clinical and health-economic challenge worldwide. Although most cases are caused by beni

K Kornél Ádám

Severe anemia-induced type 2 myocardial infarction

Orv Hetil. 2026 Feb 1;167(5):188-195. doi: 10.1556/650.2026.33475. Print 2026 Feb 1.ABSTRACTAcute bleeding can cause severe anemia-induced type 2 myocardial infarction in those with significant prior atherosclerotic coronary disease, but not plaque rupture. The authors present four cases where coron

J János Tomcsányi

Behcet's Disease: A Comprehensive Overview of Symptoms, Pathology, Genetics, and Treatment

J Mother Child. 2026 Feb 1;30(1):1-10. doi: 10.34763/jmotherandchild.20252901.d-25-00026. eCollection 2026 Jan 1.ABSTRACTBehçet's disease (BD, also called Behçet's syndrome) is a complex, chronic, and multisystemic disorder characterised by recurrent oral and genital ulcers, skin lesions, and variou

A Arbnora Batalli

Exploring the Potential of Phytotherapeutics against Auto-inflammatory Disorders: A Review

Curr Drug Res Rev. 2026 Jan 22. doi: 10.2174/0125899775393768251125072528. Online ahead of print.ABSTRACTINTRODUCTION: Various inflammatory conditions, such as arthritis, neuralgia, soft tissue injuries, and neuropathic pain, significantly affect daily quality of life. Among these, Osteoarthritis (O

S Sambhav Tyagi

Comparative efficacy of Ma Yinglong ointment and Gangtai suppository for hemorrhoids: A retrospective cohort study

Pak J Pharm Sci. 2026 Mar;39(3):763-773. doi: 10.36721/PJPS.2026.39.3.REG.15375.1.ABSTRACTBACKGROUND: Hemorrhoidal disease (HD) is a common anorectal condition that can have negative impacts on both physical and mental health as well as public health.OBJECTIVE: This retrospective analysis evaluated

X Xuxia Gao

Comparison of Mayinglong musk hemorrhoids ointment and musk hemorrhoids suppository on postoperative pain and healing in mixed hemorrhoids after PPH or RPH

Pak J Pharm Sci. 2026 Mar;39(3):744-755. doi: 10.36721/PJPS.2026.39.3.REG.15306.1.ABSTRACTBACKGROUND: Mixed hemorrhoids are common colorectal diseases; Mayinglong Musk Ointment and Musk Suppositories are used. Their post-PPH/RPH efficacy is unclear.OBJECTIVE: Compare the efficacy of Mayinglong Musk

J Jinzhou Fan

Vitamin B6 attenuates aortic dissection by inhibiting pathological remodeling of the aortic extracellular matrix

Pak J Pharm Sci. 2026 Mar;39(3):736-743. doi: 10.36721/PJPS.2026.39.3.REG.14404.1.ABSTRACTBACKGROUND: Aortic dissection (AD) is a serious medical condition characterized by a tear in the inner lining of the aorta that can lead to life-threatening complications and carries a high mortality rate. Vita

R Ru Chen

The efficacy of MLC 901 in neuron-specific enolase, functional outcome and cerebral infarct volume for acute ischemic stroke model in rats

Pak J Pharm Sci. 2026 Mar;39(3):729-735. doi: 10.36721/PJPS.2026.39.3.REG.13161.1.ABSTRACTBACKGROUND: Ischemia causes neuronal death and releases Neuron-Specific Enolase (NSE). Thrombolysis is a standard therapy for ischemic stroke, but only 10-20 percent of patients receive thrombolysis. It is nece

I Ilsa Hunaifi

Integrated approaches to preventing macrovascular complications in type 2 diabetes mellitus: Advances in secondary prevention

Pak J Pharm Sci. 2026 Mar;39(3):684-699. doi: 10.36721/PJPS.2026.39.3.REG.15014.1.ABSTRACTBACKGROUND: Type 2 diabetes mellitus (T2DM) substantially increases the risk of macrovascular complications, including coronary artery disease, cerebrovascular disease and peripheral arterial disease, which col

F Fang Qian

Nicorandil ameliorates cardiac microcirculation in hypertensive myocardial infarction via LKB1/AMPK signaling activation

Pak J Pharm Sci. 2026 Mar;39(3):604-611. doi: 10.36721/PJPS.2026.39.3.REG.14441.1.ABSTRACTBACKGROUND: Hypertension is one of the most common chronic diseases in the world, affecting about a quarter of the adult population. Its complication, hypertensive myocardial infarction (HMI), has a complex pat

W Wei Wang

The impact of aflibercept combined with dexamethasone intravitreal implant on visual function and aqueous humor inflammatory responses in diabetic macular edema

Pak J Pharm Sci. 2026 Mar;39(3):597-603. doi: 10.36721/PJPS.2026.39.3.REG.14269.1.ABSTRACTBACKGROUND: Diabetic macular edema (DME) is a predominant cause of visual impairment among patients. The concurrent administration of anti-vascular endothelial growth factor (VEGF) agents and corticosteroids ma

D Dan Luo

Revealing FPR1 as a potential pathogenic biomarker for aortic dissection based on Mendelian randomization, single-cell transcriptome and clinical data analysis

No abstractBiol Direct. 2026 Jan 31. doi: 10.1186/s13062-026-00732-4. Online ahead of print.NO ABSTRACTPMID:41620799 | DOI:10.1186/s13062-026-00732-4

Z Zihao Liu

Association between preoperative vasoactive inotropic score and clinical outcomes in severe pneumonia patients with sepsis undergoing extracorporeal membrane oxygenation: an analysis from the Chinese Society of ExtraCorporeal Life Support (CSECLS) Registry

Eur J Med Res. 2026 Jan 31. doi: 10.1186/s40001-026-03932-w. Online ahead of print.ABSTRACTBACKGROUND: Extracorporeal membrane oxygenation (ECMO) is a life-saving intervention for patients with severe respiratory and/or cardiac failure. In patients with severe pneumonia, severe septic shock led to t

W Wan Chen

Cardiovascular-kidney-metabolic syndrome: candidate subtypes and genetic risk factors

BMC Med Genomics. 2026 Jan 31. doi: 10.1186/s12920-026-02315-8. Online ahead of print.ABSTRACTBACKGROUND: Cardiovascular-kidney-metabolic (CKM) syndrome is increasingly recognized as a distinct disorder with important implications for health outcomes, but its heterogeneity of presentation and geneti

H Hylke C Donker

The association between disease status and health-related quality of life: evidence from a cross-sectional survey across mainland China

No abstractHealth Qual Life Outcomes. 2026 Jan 31. doi: 10.1186/s12955-026-02481-4. Online ahead of print.NO ABSTRACTPMID:41620732 | DOI:10.1186/s12955-026-02481-4

X Xinyi Li

Demographic, clinical, and immunological features in combined immunodeficiency patients: a comparative analysis of those with and without pulmonary manifestations - a multicenter study from Iran

BMC Pulm Med. 2026 Jan 31. doi: 10.1186/s12890-026-04115-3. Online ahead of print.ABSTRACTBACKGROUND: Combined immunodeficiency (CID) involves profound defects in B and T lymphocyte development and function. This study examined clinical and immunological phenotypes of CID patients with and without p

G Ghamartaj Khanbabaee

CFG-MambaNet: Contextual and Frequency-Guided Mamba Network for medical image segmentation

NPJ Digit Med. 2026 Jan 31. doi: 10.1038/s41746-026-02393-z. Online ahead of print.ABSTRACTAccurate medical image segmentation continues to pose significant challenges, as existing methods often struggle to concurrently achieve efficient global context modeling, precise boundary delineation, and rob

G Guoqiang Ren

Prevalence of diabetes/prediabetes and their associated risk factors among adults with hypertension from iran: a nationwide study

Sci Rep. 2026 Jan 31. doi: 10.1038/s41598-026-35998-1. Online ahead of print.ABSTRACTThe risk of cardiovascular diseases (CVDs) is significantly increased when diabetes mellitus and hypertension coexist. Improving the clinical management of people with hypertension requires understanding the prevale

M Mina Mirzad

Plasma proteome mediates the associations between air pollution exposure and disease risk

Nat Commun. 2026 Jan 31. doi: 10.1038/s41467-026-68972-6. Online ahead of print.ABSTRACTAir pollution has been increasingly linked to a wide range of diseases, yet the underlying biological mechanisms remain poorly understood. Here, we systematically investigate how circulating proteins mediate the

W Wenran Li