A prediction model for functional outcome following rescue therapy in patients with acute ischemic stroke undergoing endovascular treatment

Ann Med. 2026 Dec;58(1):2719889. doi: 10.1080/07853890.2026.2719889. Epub 2026 Aug 19.ABSTRACTOBJECTIVE: To evaluate the association between key preoperative and intraoperative factors and 90-day functional outcomes in acute ischemic stroke (AIS) patients undergoing endovascular treatment (EVT) with

X Xiaoyu Wu

High sensitivity for peripartum cardiomyopathy among large language models during differential diagnosis consideration

Womens Health (Lond). 2026 Jan-Dec;22:17455057261476573. doi: 10.1177/17455057261476573. Epub 2026 Aug 19.ABSTRACTBackgroundPeripartum cardiomyopathy (PPCM) is a rare, potentially life threatening condition with nonspecific heart failure symptoms, often leading to delayed diagnosis. Large language m

T Thomas Gausepohl

Multilingual Evidence-Based Question-Answering for Stroke Discharge Summaries: Study of Cross-Lingual Heterogeneity in Clinical Reports

J Med Internet Res. 2026 Aug 19;28:e96347. doi: 10.2196/96347.ABSTRACTBACKGROUND: The Registry of Stroke Care Quality (RES-Q) is a health care quality improvement platform used globally. RES-Q collects structured quality-of-care data for patients with stroke, requiring clinicians to manually extract

V Vojtěch Lanz

Metabolic Dysfunction-associated Steatotic Liver Disease in Romania: A Multidisciplinary Position Paper on Prevalence, Clinical Spectrum, Prevention, Screening and Management

J Gastrointestin Liver Dis. 2026 Aug 18. doi: 10.15403/jgld-7454. Online ahead of print.ABSTRACTBACKGROUND AND AIMS: Metabolic dysfunction-associated steatotic liver disease (MASLD) is the most prevalent chronic liver disease globally and a rising cause of cirrhosis, hepatocellular carcinoma, liver

L Liliana-Simona Gheorghe

Sex-related differences in outcome of tricuspid valve surgery in severe isolated secondary tricuspid regurgitation

Eur Heart J Cardiovasc Imaging. 2026 Aug 19:jeag223. doi: 10.1093/ehjci/jeag223. Online ahead of print.ABSTRACTAIMS: Significant secondary tricuspid regurgitation (STR) is associated with worse morbidity and mortality. To-date, evidence on isolated tricuspid valve surgery in STR remains controversia

J Jwan A Naser

Strategies for preventing and reversing atrial cardiomyopathy (AtCM): current evidence, therapeutic targets, and future directions. A European Journal of Heart Failure expert consensus statement

Eur J Heart Fail. 2026 Aug 19:xuag268. doi: 10.1093/ejhf/xuag268. Online ahead of print.ABSTRACTAtrial cardiomyopathy (AtCM) encompasses all forms of electrical atrial dysfunction in combination with mechanical atrial dysfunction, atrial enlargement and/or excessive atrial fibrosis. A growing body o

R Rosita Zakeri

Association of 10-year Cardiovascular Risk with Left Ventricular Hypertrophy in a Population of Nigerian Hypertensives

Niger Postgrad Med J. 2026 Sep 1;33(5):637-642. doi: 10.4103/npmj.npmj_580_25. Epub 2026 Aug 17.ABSTRACTBACKGROUND: The pooled cohort equation (PCE) for predicting the 10-year risk of atherosclerotic cardiovascular disease (ASCVD) has been utilised in Black populations to predict cardiovascular even

O Olugbenga Olusola Abiodun

Hope for heart failure with preserved ejection fraction?

Sci Adv. 2026 Aug 21;12(34):eaek5991. doi: 10.1126/sciadv.aek5991. Epub 2026 Aug 19.ABSTRACTA common form of heart failure improves when cyclic guanosine monophosphate-dependent protein kinase is activated with a novel agent that promotes cysteine-42 oxidation.PMID:42616904 | DOI:10.1126/sciadv.aek5

R Robert M Blanton

Targeting PKGIα Cys42 attenuates cardiac dysfunction in heart failure with preserved ejection fraction

Sci Adv. 2026 Aug 21;12(34):eaec8088. doi: 10.1126/sciadv.aec8088. Epub 2026 Aug 19.ABSTRACTHeart failure with preserved ejection fraction (HFpEF) is a highly prevalent condition associated with substantial morbidity and mortality, yet effective therapeutic options remain limited. As oxidation of Cy

J Jie Su

Machine Learning-Based Risk Prediction of In-Hospital Mortality in Patients With Non-ST-Elevation Acute Coronary Syndrome at Various Stages of the Diagnostic Process: Observational Study

JMIR Med Inform. 2026 Aug 19;14:e89242. doi: 10.2196/89242.ABSTRACTBACKGROUND: Despite advances in understanding and treating non-ST-elevation acute coronary syndrome (NSTE-ACS), patients continue to experience high rates of adverse outcomes, particularly those with non-ST-segment elevation myocardi

V Vyacheslav V Ryabov

Correlates of physical activity behaviour in a population sample with increased cardiovascular risk and established cardiovascular disease: Cross-sectional analysis of data from the Paracelsus 10,000 prospective cohort study in Salzburg, Austria

PLoS One. 2026 Aug 19;21(8):e0356607. doi: 10.1371/journal.pone.0356607. eCollection 2026.ABSTRACTRegular physical activity (PA) remains challenging for many people with high cardiovascular risk and established cardiovascular disease (CVD). We aimed to study correlates of PA behaviour in a populatio

S Stefan T Kulnik

Association of air pollution with diabetic microvascular complications: A prospective cohort study

PLoS One. 2026 Aug 19;21(8):e0354711. doi: 10.1371/journal.pone.0354711. eCollection 2026.ABSTRACTOBJECTIVE: To investigate the association between long-term exposure to air pollution and the risk of microvascular complications in individuals with diabetes, and provide the evidence to inform environ

Y Yuxin Nong

CASP1 as a key autophagy-related gene in atherosclerosis: Identification by bioinformatics analysis and experimental validation

PLoS One. 2026 Aug 19;21(8):e0353352. doi: 10.1371/journal.pone.0353352. eCollection 2026.ABSTRACTOBJECTIVE: This study identified potential autophagy-related genes (ARGs) in atherosclerosis using bioinformatics strategies, aiming to explore novel therapeutic targets for the clinical management of a

H Han Gao

Interaction between genistein and the endothelial activation and stress index in relation to estimated 10-year atherosclerotic cardiovascular disease risk classification

PLoS One. 2026 Aug 19;21(8):e0356477. doi: 10.1371/journal.pone.0356477. eCollection 2026.ABSTRACTBACKGROUND: The Endothelial Activation and Stress Index (EASIX) has been proposed as a marker of endothelial stress and may be associated with atherosclerotic cardiovascular disease (ASCVD) risk. Whethe

X Xinru Guo

Targeted metabolomics of postmortem human cardiac tissue using the Biocrates MxP Quant 500 kit

PLoS One. 2026 Aug 19;21(8):e0356269. doi: 10.1371/journal.pone.0356269. eCollection 2026.ABSTRACTAIM: This proof-of-concept study aimed to evaluate the feasibility and analytical performance of the Biocrates MxP® Quant 500 kit, originally developed for biofluids, to postmortem human cardiac tissue

O Oscar Emil Puntervold

Cell-specific epigenetic editing in cardiovascular disease: Mechanisms, therapeutic potential, and translational challenges

Cardiology. 2026 Aug 19:1-25. doi: 10.1159/000553321. Online ahead of print.ABSTRACTBACKGROUND: Cell-specific epigenetic editing provides a new approach to the therapy of cardiovascular disease (CVD) by rewriting pathological chromatin and RNA marks in exactly those cell populations responsible for

M Majed Alsulami

The role of mitochondrial dysfunction and genetics in female infertility and premature ovarian insufficiency

Hum Reprod Update. 2026 Aug 19:dmag022. doi: 10.1093/humupd/dmag022. Online ahead of print.ABSTRACTBACKGROUND: Female infertility occurs in ∼37% of infertile couples, while premature ovarian insufficiency (POI) impacts 1-3.7% of women under the age of 40. POI is clinically heterogeneous, with variou

B Brianna L Kline

Multicenter External Validation of an AI-Based Funduscopic Carotid Atherosclerosis Score and Assessment of Its Association With Coronary Artery Calcification: External Validation Study

JMIR Med Inform. 2026 Aug 19;14:e77335. doi: 10.2196/77335.ABSTRACTBACKGROUND: Screening for atherosclerosis is essential for early intervention, but conventional screening methods are often invasive and resource-intensive. As a result, there is growing interest in leveraging AI with noninvasive too

C Changho Han

Effects of probiotic intervention on serum lipid profiles: current evidence from systematic review and meta-analysis of randomized controlled trials

Crit Rev Food Sci Nutr. 2026 Aug 19:1-29. doi: 10.1080/10408398.2026.2714684. Online ahead of print.ABSTRACTDyslipidemia is a major risk factor for cardiovascular and metabolic diseases. Evidence suggests that probiotics may improve serum lipid profiles through multiple mechanisms, including bile sa

P Pattarachon Apisitwittaya

Peritoneal Dialysis in the Transplant Pathway: From Waitlist to Graft Failure

Kidney360. 2026 Aug 19. doi: 10.34067/KID.0000001376. Online ahead of print.ABSTRACTPeritoneal dialysis (PD) is recognized as a well-established and safe modality of replacement therapy for patients with end-stage kidney disease. Recently, its use has attracted growing interest as a bridge to kidney

C Carlo Alfieri

The Eye as a Window to Cardio-Kidney-Metabolic Disease

Clin J Am Soc Nephrol. 2026 Aug 19. doi: 10.2215/CJN.0000001224. Online ahead of print.ABSTRACTThe Cardiovascular-Kidney-Metabolic (CKM) syndrome reframes cardiovascular, kidney, and metabolic disease as an integrated continuum, yet its management relies on reactive laboratory markers with substanti

J Jung Tak Park

miR-138-5p Inhibits Aortic Valve Interstitial by Targeting SLC39A14 and Activating Nrf2 Signaling

J Biochem Mol Toxicol. 2026 Sep;40(9):e71034. doi: 10.1002/jbt.71034.ABSTRACTThis study explored the role of miR-138-5p in calcific aortic valve disease (CAVD), focusing on its regulation of osteogenic differentiation in human aortic valve interstitial cells (hAVICs) and underlying mechanisms. Aorti

F Fei Yan

Left Atrial Structure and Function, Clinical Outcomes, and Efficacy of Vutrisiran in Transthyretin Amyloidosis With Cardiomyopathy: A Secondary Analysis of the HELIOS-B Randomized Clinical Trial

JAMA Cardiol. 2026 Aug 19. doi: 10.1001/jamacardio.2026.2992. Online ahead of print.ABSTRACTIMPORTANCE: Left atrial (LA) dysfunction may play an important role in the pathophysiology of transthyretin amyloidosis with cardiomyopathy (ATTR-CM) and is driven by LA remodeling and amyloid infiltration.OB

K Karola S Jering

Smoking Behavior and Major Cardiovascular and Limb Events in Patients With Peripheral Artery Disease

JAMA Netw Open. 2026 Aug 3;9(8):e2629337. doi: 10.1001/jamanetworkopen.2026.29337.ABSTRACTIMPORTANCE: Smoking is the strongest modifiable risk factor for peripheral arterial disease (PAD), yet evidence on how postdiagnosis smoking behavior changes affect clinical outcomes remains limited.OBJECTIVE:

H Hyo Kee Kim