Oral Butyrate Reduces Progression of Kidney Damage in an L-NAME-Induced Diabetic Kidney Disease Mouse Model

Diabetes Obes Metab. 2026 Aug 18. doi: 10.1111/dom.71245. Online ahead of print.ABSTRACTAIMS: Diabetic kidney disease (DKD) is one of the main causes of kidney failure worldwide. Interestingly, patients affected by DKD are characterised by a low abundance of gut bacteria producing short fatty acids

M Maria Novella Nicese

Immature Neutrophil Phenotype and Enhanced Myeloperoxidase in Male Patients With Chronic Kidney Disease and Cardiovascular Comorbidity

Acta Physiol (Oxf). 2026 Sep;242(9):e70290. doi: 10.1111/apha.70290.ABSTRACTAIM: Patients with chronic kidney disease (CKD) have an increased cardiovascular risk. Since neutrophils and neutrophil-borne proteins contribute to cardiovascular disease, we analyzed the neutrophil phenotype in patients wi

S Sonja Vondenhoff

Long-term treatment of homozygous familial hypercholesterolemia with lomitapide: 11 years of safety and effectiveness findings from the Lomitapide Observational Worldwide Evaluation Registry

J Clin Lipidol. 2026 Jul 30:S1933-2874(26)00457-5. doi: 10.1016/j.jacl.2026.07.028. Online ahead of print.ABSTRACTBACKGROUND: Lomitapide is an oral microsomal triglyceride transfer protein inhibitor approved for homozygous familial hypercholesterolemia (HoFH).OBJECTIVE: Evaluate data from the Lomita

D Dirk J Blom

Assessing physical activity and sleep patterns in glaucoma using wearable devices

Br J Ophthalmol. 2026 Aug 18:bjo-2026-329606. doi: 10.1136/bjo-2026-329606. Online ahead of print.ABSTRACTBACKGROUND/AIMS: Glaucoma has been linked to reduced physical activity and disturbed sleep, but large-scale studies using objective wearable data are scarce. We compared activity and sleep metri

I Isaac Bernstein

A Case of Uterine Arteriovenous Fistula Associated With Adenomyosis and Pregnancy

J Obstet Gynaecol Res. 2026 Aug;52(8):e70453. doi: 10.1111/jog.70453.ABSTRACTUterine arteriovenous fistula (UAVF) associated with adenomyosis during pregnancy is a rare, life-threatening condition. This report describes a 36-year-old woman with adenomyosis who conceived through in vitro fertilizatio

Y Yuance Xu

Hereditary haemorrhagic telangiectasia presenting with refractory gastrointestinal bleeding

BMJ Case Rep. 2026 Aug 18;19(8):e275064. doi: 10.1136/bcr-2026-275064.ABSTRACTA man in his 20s presented with progressive fatigue and melena, with a history of recurrent epistaxis since adolescence and a positive family history. Evaluation revealed severe iron-deficiency anaemia (haemoglobin 27 g/L)

V Vivek Kumar Chauhan

Prophylactic implantation of implantable cardioverter-defibrillator for the primary prevention of sudden cardiac death after myocardial infarction: protocol for systematic review and meta-analysis of randomised controlled trials

BMJ Open. 2026 Aug 18;16(8):e107134. doi: 10.1136/bmjopen-2025-107134.ABSTRACTINTRODUCTION: Cardiovascular disease is a leading cause of death worldwide, of which coronary artery disease is the most common form. Sudden cardiac death (SCD) is a serious complication following acute myocardial infarcti

A Anjalee Thanuja Amarasekera

Direct oral anticoagulants in elderly patients with atrial fibrillation: a decade-long nationwide retrospective cohort study

BMJ Open. 2026 Aug 18;16(8):e121683. doi: 10.1136/bmjopen-2026-121683.ABSTRACTOBJECTIVE: To examine oral anticoagulant (OAC) prescription patterns and clinical outcomes, among elderly patients with atrial fibrillation (AF) during the era of widespread direct oral anticoagulant (DOAC) use.DESIGN: A r

H Hilmi Alnsasra

Tobacco and Marijuana Induce Adverse Effects on Cardiac Function and Platelet Activity and Reduce Tissue Preservation Following Myocardial Infarction

Am J Physiol Heart Circ Physiol. 2026 Aug 18. doi: 10.1152/ajpheart.00407.2026. Online ahead of print.ABSTRACTSmoking disrupts cardiac autonomic regulation, vascular biology, and platelet function; however, the acute and longer-term cardiovascular effects of resurging and emerging tobacco and mariju

X Xiaoyin Wang

Octyl-butyl cyanoacrylate glue versus splint for stabilising short peripheral intravenous catheters in neonates: a retrospective cohort study

BMJ Paediatr Open. 2026 Aug 18;10(1):e003716. doi: 10.1136/bmjpo-2025-003716.ABSTRACTAIM: This study was conducted to compare the effectiveness of octyl-butyl cyanoacrylate glue or limb splinting used alone or in combination for stabilising neonatal short intravenous peripheral catheters (SPCs).MATE

M Matheus Fpt van Rens

From chemical oscillators to biological synchrony: a programmable reaction-diffusion model for studying signal coordination in cardiomyocyte networks

J R Soc Interface. 2026 Aug 19;23(241):20260095. doi: 10.1098/rsif.2026.0095.ABSTRACTThe self-organization of asynchronous rhythms into synchronized beating in in vitro cardiomyocyte networks is a fundamental problem in systems biology research. Inspired by the dynamics of chemical oscillators, this

Z Zhaotong Chu

Mortality and childhood residence near the radiologically contaminated Coldwater Creek, St. Louis, Missouri

Int J Epidemiol. 2026 Aug 18;55(5):dyag166. doi: 10.1093/ije/dyag166.ABSTRACTBACKGROUND: Under the top-secret Manhattan Project, improperly stored radioactive byproducts from the processing of uranium contaminated Coldwater Creek in north St. Louis County, Missouri. We used the original 1958 Baby To

M Michael Leung

Coronary Aneurysmal and Ectatic Disease: Cath-Lab Diagnosis and Contemporary Interventional Management

Am J Cardiol. 2026 Aug 18:S0002-9149(26)00527-8. doi: 10.1016/j.amjcard.2026.08.016. Online ahead of print.ABSTRACTCoronary aneurysmal and ectatic disease (CAA/CAE) is an increasingly recognized condition in contemporary catheterization laboratory practice and is predominantly associated with athero

G Giulia Alagna

Admitting Diagnosis in In-Hospital STEMI: When the Reason for Admission Becomes a Barrier to Life-Saving Therapy

No abstractAm J Cardiol. 2026 Aug 18:S0002-9149(26)00528-X. doi: 10.1016/j.amjcard.2026.08.019. Online ahead of print.NO ABSTRACTPMID:42612893 | DOI:10.1016/j.amjcard.2026.08.019

Z Zihao Lai

Cardiovascular Implantable Electronic Device Infections Requiring Extraction: A National Analysis of Contemporary Trends, Clinical Predictors, and Economic Burden, 2016-2022

Heart Rhythm. 2026 Aug 18:S1547-5271(26)02687-1. doi: 10.1016/j.hrthm.2026.08.015. Online ahead of print.ABSTRACTBACKGROUND: Cardiovascular implantable electronic device (CIED) infections are characterized by substantial morbidity, mortality, and economic burden. Contemporary national data analysis

K Karol Quelal Analuisa

Neuropeptide Y regulates myocardial fibrosis via NPY1R/JAK2/STAT3 signaling pathway

Biochem Pharmacol. 2026 Aug 18:118372. doi: 10.1016/j.bcp.2026.118372. Online ahead of print.ABSTRACTThe level of neuropeptide Y (NPY) is elevated during the pathological progression of heart failure (HF). However, the role and molecular mechanisms of NPY in cardiac fibrosis remain largely uninvesti

W Wei Huang

PP2Acα regulates the Hippo-YAP signaling axis to promote cardiac regeneration and alleviate myocardial infarction

J Mol Cell Cardiol. 2026 Aug 18:S0022-2828(26)00127-6. doi: 10.1016/j.yjmcc.2026.08.009. Online ahead of print.ABSTRACTLimited proliferative capacity of cardiomyocytes (CMs) underlies persistent CM loss and cardiac dysfunction after myocardial infarction (MI). Although neonatal mammalian hearts reta

A Anhui Wang

Distinct Cardiac Profiles in Psoriatic Arthritis and Rheumatoid Arthritis: Insights from Echocardiographic Findings

Joint Bone Spine. 2026 Aug 18:106124. doi: 10.1016/j.jbspin.2026.106124. Online ahead of print.ABSTRACTOBJECTIVE: Cardiovascular disease contributes to morbidity and mortality in rheumatoid arthritis (RA) and psoriatic arthritis (PsA). Systemic inflammation drives risk in RA, while PsA may involve a

F Fabiola Atzeni

Ethics of Incidental Skin Findings with Potential Systemic Implications

No abstractJ Am Acad Dermatol. 2026 Aug 18:S0190-9622(26)03363-3. doi: 10.1016/j.jaad.2026.08.046. Online ahead of print.NO ABSTRACTPMID:42612805 | DOI:10.1016/j.jaad.2026.08.046

S Sophia Ma

4D flow cardiac magnetic resonance postprocessing in congenital heart disease: SCMR FLIICR workgroup recommendations

J Cardiovasc Magn Reson. 2026 Aug 18:102789. doi: 10.1016/j.jocmr.2026.102789. Online ahead of print.ABSTRACTThe large majority of patients with congenital heart disease (CHD) survive into adulthood in the modern era of surgical advancements. However, patients require life-long follow-up and non-inv

J Julio Garcia

Cytomegalovirus Infection and Epicardial Adipose Tissue in Liver Transplant Recipients - Results from a Nationwide Prospective Cohort Study

Int J Infect Dis. 2026 Aug 18:109048. doi: 10.1016/j.ijid.2026.109048. Online ahead of print.ABSTRACTOBJECTIVES: Liver transplant recipients face increased cardiovascular disease (CVD) risk, but the pathogenesis is not clear. Cytomegalovirus (CMV) infection, which is common after liver transplantati

K Kathrine Underlien Emde

Aucubin as a multifunctional iridoid glycoside: Molecular pharmacology and therapeutic mechanisms supporting its potential as a drug discovery scaffold

Eur J Pharmacol. 2026 Aug 18:179254. doi: 10.1016/j.ejphar.2026.179254. Online ahead of print.ABSTRACTAucubin is a widely distributed iridoid glycoside that has gained increasing attention as a multifunctional scaffold in natural product-based drug discovery. Occurring predominantly in Plataginaceae

M Mahmoud A M Arafat

Patient experience data as a methodological and strategic innovation in clinical trial design

Drug Discov Today. 2026 Aug 18:104775. doi: 10.1016/j.drudis.2026.104775. Online ahead of print.ABSTRACTPatient experience data (PED) are increasingly recognised as a methodological and strategic innovation in drug development, yet their implementation in clinical trial design remains inconsistent.

A Alice Vanneste

A novel lncPEAN inhibits the proliferation, invasion and migration of trophoblasts via WDR74/TGF-β1/Smad pathway

Cell Signal. 2026 Aug 18:112832. doi: 10.1016/j.cellsig.2026.112832. Online ahead of print.ABSTRACTPreeclampsia is believed to result from impaired placentation caused by insufficient trophoblast invasion, which leads to defective remodeling of uterine spiral arteries and inadequate uteroplacental a

N Ning Ding