Acta Cardiol. 2026 May;81(3):265-269. doi: 10.1080/00015385.2026.2664284. Epub 2026 May 11.ABSTRACTOver the past two decades, cardiovascular interventions have undergone major transformation, extending indications while improving safety and efficiency. The focus has progressively shifted from proced
Stroke. 2026 May 11. doi: 10.1161/STROKEAHA.126.055466. Online ahead of print.ABSTRACTBACKGROUND: Hemorrhagic risk in dural arteriovenous fistulas (dAVFs) is largely determined by venous anatomy, but the contribution of systemic cardiovascular factors and their medical therapy remains poorly defined
Ann Med. 2026 Dec;58(1):2667620. doi: 10.1080/07853890.2026.2667620. Epub 2026 May 11.ABSTRACTBACKGROUND: No data exist on whether ischemic stroke admissions among patients with atrial fibrillation (AF) vary by day of the week.METHODS: The nationwide registry-linkage FinACAF study includes all patie
Ann Med. 2026 Dec;58(1):2667553. doi: 10.1080/07853890.2026.2667553. Epub 2026 May 11.ABSTRACTBACKGROUND: Targeted drug delivery systems achieve precise drug enrichment at lesion sites through mechanisms such as passive targeting, active targeting, and stimulus-responsive release, offering novel pat
Kidney Res Clin Pract. 2026 May 11. doi: 10.23876/j.krcp.25.447. Online ahead of print.ABSTRACTBACKGROUND: Remnant cholesterol is a known residual risk factor for cardiovascular disease in the general population. However, its prognostic value in patients undergoing dialysis, a population at a high r
Kidney Res Clin Pract. 2026 May 11. doi: 10.23876/j.krcp.25.091. Online ahead of print.ABSTRACTBACKGROUND: Polypharmacy (PP) is common among kidney transplant recipients (KTRs) due to lifelong immunosuppressive therapy and comorbidity management. However, PP's impact on clinical outcomes remains unc
J Clin Neurol. 2026 May;22(3):327-337. doi: 10.3988/jcn.2025.0556.ABSTRACTBACKGROUND AND PURPOSE: Spinal and bulbar muscular atrophy (SBMA) is a rare X-linked neuromuscular disorder characterized by slowly progressive motor decline. However, there is no specific fluid marker that reflects the severi
Physiol Rep. 2026 May;14(9):e70903. doi: 10.14814/phy2.70903.ABSTRACTChronic volume overload is a major risk factor of hypertension and mortality in chronic dialysis patients. However, the mechanisms responsible for hypertension are unclear. We studied 32 patients (age 23-68 years, 19 females) in ch
Clin Transl Med. 2026 May;16(5):e70677. doi: 10.1002/ctm2.70677.ABSTRACTBACKGROUND: Hepatic ischaemia/reperfusion (I/R) injury poses a common clinical dilemma encountered during liver transplantation (LT), characterised by substantial cellular death and inflammation reactions. Ubc9, the sole E2 conj
Am J Case Rep. 2026 May 11;27:e951645. doi: 10.12659/AJCR.951645.ABSTRACTBACKGROUND Familial Turner syndrome (TS) is an uncommon sex chromosome abnormality, typically characterized by the transmission of identical X-chromosomal aberrations (eg, partial or complete deletions) within a lineage. The oc
Med Sci Monit. 2026 May 11;32:e952109. doi: 10.12659/MSM.952109.ABSTRACTBACKGROUND Elderly patients with both coronary heart disease (CHD) and diabetes mellitus (DM) undergoing off-pump coronary artery bypass grafting (CABG) face high risks of perioperative glucose fluctuations and impaired recovery
Cardiol Rev. 2026 May 11. doi: 10.1097/CRD.0000000000001310. Online ahead of print.ABSTRACTRetatrutide is a first-in-class, unimolecular triple hormone receptor agonist targeting glucose-dependent insulinotropic polypeptide, glucagon-like peptide-1, and glucagon receptors. By synergizing incretin-me
Cardiol Rev. 2026 May 11. doi: 10.1097/CRD.0000000000001290. Online ahead of print.ABSTRACTSodium-glucose cotransporter 2 inhibitors have demonstrated substantial cardiovascular and renal benefits in adults, including reduced heart failure events across diabetic and nondiabetic populations. However,
Cardiol Rev. 2026 May 11. doi: 10.1097/CRD.0000000000001308. Online ahead of print.ABSTRACTCardiovascular disease and chronic kidney disease remain the leading causes of morbidity and mortality in patients with type 2 diabetes, even when conventional risk factors are well managed. Two drug classes h
Cell Commun Signal. 2026 May 11. doi: 10.1186/s12964-026-02919-8. Online ahead of print.ABSTRACTPurinergic signaling is critical to myocardial inflammation and function. However, the underlying mechanisms are not well defined. Herein, we identified a protein kinase, homeodomain-interacting protein k
Genome Biol. 2026 May 11. doi: 10.1186/s13059-026-04095-x. Online ahead of print.ABSTRACTWhile many computational tools exist for designing CRISPR-Cas experiments, there is a need for a centralized resource that combines individual tools to predict the most efficient genome editing strategy for a gi
Endocrinol Diabetes Metab. 2026 May;9(3):e70199. doi: 10.1002/edm2.70199.ABSTRACTOBJECTIVES: This study aimed to identify key hypertension (HTN) risk factors using machine learning (ML) models to enhance prediction accuracy.METHODS: Data from the Mashhad stroke and heart atherosclerotic disorder (MA
Cancer Med. 2026 May;15(5):e71911. doi: 10.1002/cam4.71911.ABSTRACTMinimal residual disease (MRD) testing is essential for evaluating treatment response among multiple myeloma (MM) patients. Many patients experience MRD progression (MRD-P) before they meet the criteria for clinical or biochemical pr
Med J Aust. 2026 May;224(5):e70195. doi: 10.5694/mja2.70195.ABSTRACTMetabolic (dysfunction)-associated fatty liver disease (MAFLD) or metabolic (dysfunction)-associated steatotic liver disease (MASLD) is the most common and fastest growing cause of chronic liver disease worldwide. There has been a s
Clin Rev Allergy Immunol. 2026 May 11;69(1):43. doi: 10.1007/s12016-026-09164-4.ABSTRACTSystemic lupus erythematosus (SLE) is a heterogeneous autoimmune disease characterized by chronic immune activation, relapsing-remitting clinical progression, and progressive multi-organ damage. In addition to th
Nat Med. 2026 May 10. doi: 10.1038/s41591-026-04408-4. Online ahead of print.ABSTRACTMicroRNA-132 (miR-132) is a central regulator of adverse cardiac remodeling. Here we evaluated CDR132L, a synthetic antisense oligonucleotide miR-132 inhibitor, in a multinational, randomized, double-blind, placebo-
Sci Rep. 2026 May 10. doi: 10.1038/s41598-026-47839-2. Online ahead of print.ABSTRACTPNPLA3-I148M, the greatest genetic determinant for metabolic dysfunction-associated steatotic liver disease (MASLD), paradoxically associates with reduced cardiovascular disease (CVD); however, the mechanisms are po
Med Phys. 2026 May;53(5):e70461. doi: 10.1002/mp.70461.ABSTRACTBACKGROUND: Aortic dissection (AD) is a life-threatening cardiovascular emergency. For Type B AD (TBAD), rapid and accurate identification of the true lumen (TL), false lumen (FL), and false lumen thrombus (FLT) from CTA is critical for
J Formos Med Assoc. 2026 May 9:S0929-6646(26)00466-3. doi: 10.1016/j.jfma.2026.04.127. Online ahead of print.ABSTRACTBACKGROUND: The gut microbiota plays a pivotal role in host lipid metabolism and cardiovascular health. However, comparative profiling of microbial composition and predicted metabolic
