Therapeutic Plasma Exchange for Uncontrollable Bleeding After Platelet Inhibition with Ticagrelor: A Report of 2 Cases

Am J Case Rep. 2026 Mar 22;27:e950336. doi: 10.12659/AJCR.950336.ABSTRACTBACKGROUND Acute coronary syndrome is the most common cause of death in the United States. Successful intervention often requires a multi-therapeutic approach, including percutaneous coronary intervention (PCI) and antiplatelet

A Amanda Herrmann

Next-generation molecular imaging of cardiac fibrosis

No abstractInt J Cardiovasc Imaging. 2026 Mar 21. doi: 10.1007/s10554-026-03682-0. Online ahead of print.NO ABSTRACTPMID:41865202 | DOI:10.1007/s10554-026-03682-0

M Martin Ezeani

Continuous glucose monitoring and risks of acute and chronic diabetes-related complications and mortality in adults with type 1 diabetes: a nationwide cohort study

Diabetologia. 2026 Mar 21. doi: 10.1007/s00125-026-06709-2. Online ahead of print.ABSTRACTAIMS/HYPOTHESIS: We investigated the association between continuous glucose monitoring (CGM) and acute and chronic diabetes-related complications and mortality risk in adults with type 1 diabetes.METHODS: This

J Ji Yoon Kim

Targeting STAT3 pathway attenuates macrophages inflammation and cardiovascular injury in a model of Kawasaki disease

Sci Rep. 2026 Mar 21. doi: 10.1038/s41598-026-45051-w. Online ahead of print.ABSTRACTSignal transducer and activator of transcription (STAT) 3 contributes to the development of cardiovascular diseases by modulating macrophages inflammation. However, the underlying implication of STAT3 pathway in Kaw

F Fenglei Zheng

Identifying genetic contributions of 6q21 loci and PPAR pathway to antipsychotic-induced metabolic syndrome: a Sex-Stratified Multi-Omics study

Mol Psychiatry. 2026 Mar 21. doi: 10.1038/s41380-026-03544-0. Online ahead of print.ABSTRACTAntipsychotics-induced metabolic syndrome (APs-induced MetS) is a common side-effect of antipsychotics, significantly increasing the risk of cardiovascular diseases and mortality. However, the genetic risk fa

G Guorui Zhao

Mechanistic role of gut microbiota metabolites in hypertension-insomnia comorbidity via integrated network pharmacology and molecular dynamics

Sci Rep. 2026 Mar 22. doi: 10.1038/s41598-026-44114-2. Online ahead of print.ABSTRACTHypertension and insomnia frequently co-occur, yet their molecular link is unclear. Recent studies indicate that gut microbiota metabolites significantly influence neuroimmune and cardiovascular interactions. This r

R Rui-Ling Ma

Quercetin and nanoquercetin mitigate high fat diet-induced obesity via lipid modulation, genomic DNA integrity restoration, adipokine regulation, and hepato-pancreatic tissue preservation

Sci Rep. 2026 Mar 22. doi: 10.1038/s41598-026-41808-5. Online ahead of print.ABSTRACTObesity is a global health challenge characterized by excessive fat accumulation and associated with life-threatening comorbidities such as type 2 diabetes, cardiovascular diseases, and certain cancers. Conventional

M Marwa A Lotify

Retrospective study: clinical analysis of Kawasaki disease complicated with macrophage activation syndrome

No abstractItal J Pediatr. 2026 Mar 21. doi: 10.1186/s13052-026-02239-0. Online ahead of print.NO ABSTRACTPMID:41864993 | DOI:10.1186/s13052-026-02239-0

W Wenhui Bie

Hybrid ablation in a patient with atypical atrial flutter originating from a left atrial appendage aneurysm: a case report

No abstractJ Cardiothorac Surg. 2026 Mar 21. doi: 10.1186/s13019-026-03907-2. Online ahead of print.NO ABSTRACTPMID:41864981 | DOI:10.1186/s13019-026-03907-2

A Antoni Wileczek

The role of lipid lowering medications in the primary prevention of cardiovascular disease and mortality: a meta-analysis of randomized controlled trials

No abstractBMC Cardiovasc Disord. 2026 Mar 21. doi: 10.1186/s12872-026-05659-2. Online ahead of print.NO ABSTRACTPMID:41864911 | DOI:10.1186/s12872-026-05659-2

B Brooke Morsell

Circulating cardiometabolic metabolite profiles associated with ambient air pollution and atrial fibrillation risk: a prospective cohort study

Cardiovasc Diabetol. 2026 Mar 21. doi: 10.1186/s12933-026-03129-9. Online ahead of print.ABSTRACTBACKGROUND: Ambient air pollution has been linked to atrial fibrillation (AF), yet the underlying metabolic mechanisms remain poorly understood.METHODS: We analyzed 227,324 UK Biobank participants withou

T Tonghuan Shi

Long-term prognostic value of apolipoprotein Β levels in patients with very premature (≤40 years) acute coronary syndrome

J Clin Lipidol. 2026 Mar 3:S1933-2874(26)00063-2. doi: 10.1016/j.jacl.2026.02.024. Online ahead of print.ABSTRACTBACKGROUND: Apolipoprotein B (apoB) is a recognized risk factor for acute coronary syndrome (ACS); however, its prognostic value in secondary prevention and superiority over other lipid b

L Loukianos S Rallidis

Hemoglobin A1c is more predictive of type 1 myocardial infarction than low-density lipoprotein or body mass index

Nutr Metab Cardiovasc Dis. 2026 Feb 17:104626. doi: 10.1016/j.numecd.2026.104626. Online ahead of print.ABSTRACTBACKGROUND AND AIMS: Dyslipidemia and diabetes are traditional risk factors for myocardial infarction (MI), with obesity and prediabetes now recognized as non-traditional ones. Few studies

T Tiago Palmisano

AISF practice guidance on pharmacological treatment of metabolic-dysfunction associated steatotic liver disease and steatohepatitis (MASLD/MASH): A 2026 Update

Dig Liver Dis. 2026 Mar 20:S1590-8658(26)00292-6. doi: 10.1016/j.dld.2026.02.014. Online ahead of print.ABSTRACTMetabolic dysfunction-associated steatotic liver disease (MASLD) has rapidly emerged as the leading cause of chronic liver disease worldwide, gradually replacing viral hepatitis in clinica

A Associazione Italiana per lo Studio del Fegato (AISF)

Angiography-derived fractional flow reserve versus coronary angiography to guide coronary artery bypass grafting in patients undergoing surgical valve procedures with concomitant coronary artery disease in China (FAVOR IV-QVAS): a multicentre, triple-blind, randomised trial

Lancet. 2026 Mar 21;407(10534):1161-1170. doi: 10.1016/S0140-6736(25)02418-3.ABSTRACTBACKGROUND: For patients undergoing surgical valve procedures with concomitant coronary artery disease, current guidelines recommend that coronary artery bypass grafting (CABG) should be anatomically guided on the b

Y Yunpeng Zhu

From canes to pills: the evolution of carbon monoxide therapeutics

Adv Drug Deliv Rev. 2026 Mar 19:115858. doi: 10.1016/j.addr.2026.115858. Online ahead of print.ABSTRACTCarbon monoxide (CO) has gained increasing attention as an endogenous gasotransmitter with potential therapeutic relevance. In preclinical studies, including acute lung injury, sepsis, transplantat

F Fiona Halbig

HADHA in Cardiovascular Disease: From Mitochondrial Dysfunction to Therapeutic Targets

Ageing Res Rev. 2026 Mar 19:103106. doi: 10.1016/j.arr.2026.103106. Online ahead of print.ABSTRACTHADHA, encoding the α-subunit of MTP, plays a pivotal role in long-chain fatty acid β-oxidation and mitochondrial energy homeostasis. HADHA dysfunction disrupts energy balance by causing toxic metabolit

Y Yichen Qi

Survival After Coronary Artery Bypass Grafting With or Without Mitral Valve Repair for Moderate Ischemic Mitral Regurgitation

Ann Thorac Surg. 2026 Mar 19:S0003-4975(26)00233-X. doi: 10.1016/j.athoracsur.2026.03.016. Online ahead of print.ABSTRACTBACKGROUND: The surgical management of moderate ischemic mitral regurgitation (IMR) in patients undergoing coronary artery bypass grafting (CABG) remains controversial, with limit

L Lianxin Chen

Transcatheter vs Surgical Tricuspid Valve Repair: An Analysis of Medicare Beneficiaries

Ann Thorac Surg. 2026 Mar 19:S0003-4975(26)00230-4. doi: 10.1016/j.athoracsur.2026.03.013. Online ahead of print.ABSTRACTBACKGROUND: In patients with tricuspid regurgitation (TR), surgical and transcatheter interventions aim to impact outcomes and symptomatic quality of life. Compared tricuspid tran

J J Hunter Mehaffey

Exercise enhances cardiac Pect expression to restore phosphatidylethanolamine synthesis and alleviate high-sugar diet-induced cardiac dysfunction in Drosophila

Life Sci. 2026 Mar 19:124345. doi: 10.1016/j.lfs.2026.124345. Online ahead of print.ABSTRACTHigh dietary sugar intake is recognized as an important risk factor for cardiovascular disease, yet the precise mechanisms that drive these pathologies remain incompletely understood. To delineate the molecul

Z Zike Zhang

Characteristics and outcomes of Operated versus non-Operated Patients with infective Endocarditis and ceRebral complications: the COOPER study

Can J Cardiol. 2026 Mar 19:S0828-282X(26)00271-0. doi: 10.1016/j.cjca.2026.03.022. Online ahead of print.ABSTRACTBACKGROUND: Cerebral complications in patients with infective endocarditis (IE) are common and worsen prognosis. Determining the optimal timing for cardiac surgery in this context remains

O Olivia Graveleau

The Scientific Justification for Abandoning Risk Factor-based Guidelines for the Prevention of Atherosclerotic Cardiovascular Disease

No abstractAm J Med. 2026 Mar 19:S0002-9343(26)00218-4. doi: 10.1016/j.amjmed.2026.03.018. Online ahead of print.NO ABSTRACTPMID:41864406 | DOI:10.1016/j.amjmed.2026.03.018

D David S Schade

Tribbles Pseudokinases in Cardiovascular Diseases: Molecular Mechanisms, Genetic Insights, and Therapeutic Prospects

Pharmacol Res. 2026 Mar 19:108168. doi: 10.1016/j.phrs.2026.108168. Online ahead of print.ABSTRACTCardiovascular disease (CVD) represents a significant global public health challenge, with its high incidence and mortality rates imposing a substantial socioeconomic burden. Tribbles family proteins (T

W Wenkang Zhang

Joint effects of cardiometabolic index and remnant cholesterol on cardiovascular disease in cardiovascular-kidney-metabolic syndrome stages 0-3: a nationwide cohort study

Exp Gerontol. 2026 Mar 19:113102. doi: 10.1016/j.exger.2026.113102. Online ahead of print.ABSTRACTBACKGROUND: The cardiometabolic index (CMI) and remnant cholesterol (RC) reflect different aspects of adiposity and triglyceride-rich lipoprotein metabolism in cardiovascular-kidney-metabolic (CKM) synd

X Xiaojing Zhou