N Engl J Med. 2026 Jan 29;394(5):486-496. doi: 10.1056/NEJMcp2501200.ABSTRACTPeripheral artery disease affects approximately 236 million persons worldwide and is diagnosed with an ankle-brachial index of less than 0.90. Among older persons, 3.3% of those without peripheral artery disease, 18.1% with
N Engl J Med. 2026 Jan 29;394(5):442-450. doi: 10.1056/NEJMoa2508515.ABSTRACTBACKGROUND: Central retinal artery occlusion can result in permanent vision loss. Effective treatment is lacking.METHODS: We conducted a phase 3, double-blind, double-dummy, randomized, controlled trial involving adults wit
Eur J Gastroenterol Hepatol. 2026 Jan 15. doi: 10.1097/MEG.0000000000003140. Online ahead of print.ABSTRACTBACKGROUND AND AIMS: Cardiovascular disease is the main cause of mortality in metabolic-associated steatotic liver disease (MASLD). This study evaluated both observed and predicted cardiovascul
Adv Sci (Weinh). 2026 Jan 28:e12842. doi: 10.1002/advs.202512842. Online ahead of print.ABSTRACTIdentifying molecular drivers and diagnostic genes for neurocognitive disorders (NDs) remains a major challenge due to the prevalence of variants of uncertain significance (VUS) and limitations in current
Long-term exposure to fine particulate matter (PM(2.5)) is a well-established risk factor for cardiovascular disease (CVD) mortality, yet the contributions of its components remain unclear, particularly across geographic regions and racial/ethnic groups. We extended the generalized weighted quantile
Transplantation. 2026 Jan 28. doi: 10.1097/TP.0000000000005622. Online ahead of print.ABSTRACTBACKGROUND: Prolonged cold myocardial ischemia/reperfusion injury-driven by mitochondrial dysfunction, oxidative stress, and ferroptosis-limits cardiac transplantation success. Dihydroorotate dehydrogenase
Cardiovasc Res. 2026 Jan 28:cvag032. doi: 10.1093/cvr/cvag032. Online ahead of print.ABSTRACTAIM: The burden of dyslipidaemia is increasing, and the association of dietary exposure, especially vegetable consumption, with dyslipidaemia among Africans is poorly characterized. This study evaluated the
Eur Heart J Cardiovasc Imaging. 2026 Jan 28:jeag022. doi: 10.1093/ehjci/jeag022. Online ahead of print.ABSTRACTAIMS: Conflicting results have been reported on the prognostic value of coronary stenosis grade and plaque burden. We aimed to investigate the time-varying risk for cardiovascular events as
No abstractJ Hypertens. 2026 Mar 1;44(3):530. doi: 10.1097/HJH.0000000000004228. Epub 2026 Jan 29.NO ABSTRACTPMID:41604354 | DOI:10.1097/HJH.0000000000004228
Int J Cardiol. 2026 Feb 1;444:133993. doi: 10.1016/j.ijcard.2025.133993. Epub 2025 Oct 24.ABSTRACTBACKGROUND: Obstructive sleep apnea (OSA) is commonly observed in patients with heart failure with preserved ejection fraction (HFpEF), exacerbating the severity of the disease. Identifying the composit
Int J Cardiol. 2026 Feb 1;444:133992. doi: 10.1016/j.ijcard.2025.133992. Epub 2025 Oct 24.ABSTRACTINTRODUCTION: Bundle branch block (BBB) it is often associated with underlying heart conditions, but little is known about prognosis of patients admitted to intensive cardiovascular care unit and BBB on
Acta Obstet Gynecol Scand. 2026 Jan 28. doi: 10.1111/aogs.70137. Online ahead of print.ABSTRACTINTRODUCTION: Tetralogy of Fallot (ToF) shows variability in neonatal outcomes, and identifying reliable prenatal predictors is essential for optimizing perinatal management. The aim of this study was to d
Nutr Health. 2026 Jan 28:2601060251414572. doi: 10.1177/02601060251414572. Online ahead of print.ABSTRACTBackground: Hyperuricaemia increases the risk of gout, and cardiovascular disease, thus dietary modifications that reduce urate are of interest. Cherries have been reported to lower urate, but st
Eur J Cardiothorac Surg. 2026 Jan 28:ezag009. doi: 10.1093/ejcts/ezag009. Online ahead of print.ABSTRACTOBJECTIVES: Sex-related disparities are well established in cardiovascular disease, but their impact on outcomes after valve-sparing root replacement (VSRR) is not well defined. In a multicentre i
J Am Soc Nephrol. 2026 Jan 28. doi: 10.1681/ASN.0000001006. Online ahead of print.ABSTRACTBACKGROUND: Lowering low-density lipoprotein cholesterol (LDL cholesterol) reduces the risk of atherosclerotic cardiovascular disease in patients with chronic kidney disease (CKD). The efficacy and safety of in
Stem Cells Transl Med. 2026 Jan 26;15(2):szag001. doi: 10.1093/stcltm/szag001.ABSTRACTHuman-induced pluripotent stem cell (hiPSC) technologies have provided access to in vitro models of inaccessible human cardiomyocytes (CMs), providing new insights into human disease mechanisms, therapy strategies,
Nephrol Dial Transplant. 2026 Jan 28:gfag014. doi: 10.1093/ndt/gfag014. Online ahead of print.ABSTRACTThe 2026 Kidney Disease: Improving Global Outcomes (KDIGO) Clinical Practice Guideline for Anemia in Chronic Kidney Disease represents a substantial update, more than a decade since the previous KDI
JAMA Cardiol. 2026 Jan 28. doi: 10.1001/jamacardio.2025.5305. Online ahead of print.ABSTRACTIMPORTANCE: The prevalence of obesity and cardiovascular-kidney-metabolic (CKM) syndrome continues to rise. Indications for novel CKM therapies, including glucagonlike peptide 1 receptor agonists (GLP-1RAs),
Europace. 2026 Jan 12;28(1):euaf316. doi: 10.1093/europace/euaf316.ABSTRACTAIMS: The rising burden of cardiovascular diseases, especially atrial fibrillation, has increased demand for electrophysiology (EP) procedures in Europe, driving greater reliance on disposable devices like diagnostic and abla
JAMA Netw Open. 2026 Jan 2;9(1):e2555952. doi: 10.1001/jamanetworkopen.2025.55952.ABSTRACTIMPORTANCE: Patients with diabetes and a history of major adverse limb events (MALEs) are at an increased risk of cardiovascular and limb-related complications; however, effective glucose-lowering therapies for
JAMA Netw Open. 2026 Jan 2;9(1):e2556012. doi: 10.1001/jamanetworkopen.2025.56012.ABSTRACTIMPORTANCE: The associations of adverse childhood experiences (ACEs) and adverse adulthood experiences (AAEs) with incident dementia and stroke in the Chinese population are not well understood.OBJECTIVES: To i
No abstractMol Cell Biochem. 2026 Jan 28. doi: 10.1007/s11010-026-05483-4. Online ahead of print.NO ABSTRACTPMID:41604122 | DOI:10.1007/s11010-026-05483-4
No abstractJ Thromb Thrombolysis. 2026 Jan 28. doi: 10.1007/s11239-025-03208-w. Online ahead of print.NO ABSTRACTPMID:41604106 | DOI:10.1007/s11239-025-03208-w
Cardiol Ther. 2026 Jan 28. doi: 10.1007/s40119-026-00444-w. Online ahead of print.ABSTRACTINTRODUCTION: The PRECISE-DAPT score is a useful tool for predicting the risk of bleeding after percutaneous coronary intervention (PCI) requiring dual antiplatelet therapy. We aimed to validate the PRECISE-DAP
