J Endovasc Ther. 2025 Oct 14:15266028251382882. doi: 10.1177/15266028251382882. Online ahead of print.ABSTRACTPURPOSE: Full-moon calcified plaque is difficult to treat in coronary arteries. Computed tomography (CT) is used to evaluate calcification, but severe plaque can be difficult to assess due t
Circ Res. 2025 Nov 26. doi: 10.1161/CIRCRESAHA.125.326628. Online ahead of print.ABSTRACTBACKGROUND: Genome-wide association studies have identified multiple novel loci that contribute to coronary artery disease pathogenesis, but the mechanisms of these associations remain largely unknown.METHODS: I
Hypertension. 2025 Nov 26. doi: 10.1161/HYPERTENSIONAHA.125.24666. Online ahead of print.ABSTRACTBACKGROUND: The influence of IR (insulin resistance) on the response of patients with hypertension to intensive systolic blood pressure treatment in terms of cognitive performance remains unclear, as doe
Front Endocrinol (Lausanne). 2025 Nov 10;16:1683354. doi: 10.3389/fendo.2025.1683354. eCollection 2025.ABSTRACTBACKGROUND: The presence of proteinuria or microalbuminuria is significantly associated with an increased risk of cardiovascular disease and all-cause mortality. Several studies reported th
Front Endocrinol (Lausanne). 2025 Nov 10;16:1631647. doi: 10.3389/fendo.2025.1631647. eCollection 2025.ABSTRACTINTRODUCTION: This study aimed to develop a diabetic retinopathy (DR) Prediction model using various machine learning algorithms incorporating the novel predictor Triglyceride-glucose index
J Vasc Bras. 2025 Oct 27;24:e20240186. doi: 10.1590/1677-5449.202401862. eCollection 2025.ABSTRACTAtherosclerosis is a chronic inflammation of the artery wall caused by injury to the vascular endothelium and influenced by many different risk factors. Carotid stenosis is a crucial marker of cardiovas
Front Cardiovasc Med. 2025 Nov 10;12:1705201. doi: 10.3389/fcvm.2025.1705201. eCollection 2025.ABSTRACTMast cell activation disease is a genetic disease entity characterized by a very pronounced clinical symptomatology with potential manifestations in virtually every organ and tissue. These arise fr
Front Cardiovasc Med. 2025 Nov 10;12:1622275. doi: 10.3389/fcvm.2025.1622275. eCollection 2025.ABSTRACTBACKGROUND: Heart failure with preserved ejection fraction (HFpEF) is defined as presenting with clinical symptoms and signs of heart failure with a concomitant left ventricular ejection fraction ≥
Front Cardiovasc Med. 2025 Nov 10;12:1593481. doi: 10.3389/fcvm.2025.1593481. eCollection 2025.ABSTRACTOBJECTIVE: This systematic review and meta-analysis aimed to examine the link between the systemic immune inflammation index (SII) and the incidence and clinical outcomes of hypertension (HTN).METH
Cureus. 2025 Nov 23;17(11):e97588. doi: 10.7759/cureus.97588. eCollection 2025 Nov.ABSTRACTBACKGROUND: Steroidal mineralocorticoid receptor antagonists (MRAs) reduce morbidity in heart failure (HF) but frequently cause hyperkalemia, limiting long-term use. Non-steroidal MRAs such as finerenone offe
Cureus. 2025 Nov 24;17(11):e97665. doi: 10.7759/cureus.97665. eCollection 2025 Nov.ABSTRACTBackground and aims Functionally univentricular hearts (UVH) are a relatively rare congenital heart defect and often require staged palliation leading to the Fontan circulation. The bidirectional superior cavo
J Multidiscip Healthc. 2025 Nov 20;18:7579-7592. doi: 10.2147/JMDH.S535959. eCollection 2025.ABSTRACTBACKGROUND: Arrhythmias in pregnancy have become an increasingly significant concern for maternal and fetal well-being, reflecting a rising prevalence trend. This bibliometric analysis sought to deli
Clin Interv Aging. 2025 Nov 20;20:2091-2104. doi: 10.2147/CIA.S557166. eCollection 2025.ABSTRACTPURPOSE: To utilize the developed nomogram for evaluating the risk of recurrence in non-valvular atrial fibrillation (NVAF) patients after radiofrequency catheter ablation (RFCA) and compare the model's p
Front Cell Dev Biol. 2025 Nov 10;13:1698110. doi: 10.3389/fcell.2025.1698110. eCollection 2025.ABSTRACTAtherosclerosis (AS) is a chronic cardiovascular disease and a leading cause of global morbidity and mortality. Its pathological features include lipid accumulation within the arterial walls, macro
Front Cell Dev Biol. 2025 Nov 10;13:1661965. doi: 10.3389/fcell.2025.1661965. eCollection 2025.ABSTRACTMicroRNAs (miRNAs) are critical post-transcriptional regulators of gene expression and have been extensively implicated in cardiovascular development, homeostasis, and disease. Among them, microRNA
Cureus. 2025 Oct 25;17(10):e95400. doi: 10.7759/cureus.95400. eCollection 2025 Oct.ABSTRACTThis systematic review evaluated the impact of contemporary therapies on cardiovascular (CV) and renal outcomes in patients with diabetic kidney disease (DKD), with a particular focus on finerenone as a novel
Cureus. 2025 Oct 24;17(10):e95298. doi: 10.7759/cureus.95298. eCollection 2025 Oct.ABSTRACTTakotsubo cardiomyopathy is a rare, reversible form of acute left ventricular dysfunction triggered by a catecholamine surge in response to severe stress. We report the case of a 42-year-old woman who develope
Cureus. 2025 Oct 25;17(10):e95397. doi: 10.7759/cureus.95397. eCollection 2025 Oct.ABSTRACTINTRODUCTION: Metabolic syndrome (MetS) is a cluster of conditions that increases the risk of cardiovascular disease and diabetes. It has become a major global health concern, significantly affecting adults wo
Cureus. 2025 Oct 24;17(10):e95354. doi: 10.7759/cureus.95354. eCollection 2025 Oct.ABSTRACTINTRODUCTION: Heart failure with reduced ejection fraction (HFrEF) is a major contributor to cardiovascular morbidity and mortality worldwide. This condition is associated with delayed diagnosis and high comor
Cureus. 2025 Oct 24;17(10):e95303. doi: 10.7759/cureus.95303. eCollection 2025 Oct.ABSTRACTLeft atrial appendage (LAA) thrombus formation is a clinically significant complication that can occur in patients with atrial fibrillation (AF), particularly in the setting of coexisting conditions that affec
Front Pharmacol. 2025 Nov 10;16:1692472. doi: 10.3389/fphar.2025.1692472. eCollection 2025.ABSTRACTBACKGROUND: Alpha-calcitonin gene-related peptide (α-CGRP) is a cardioprotective neuropeptide. However, due to low bioavailability, its use as a therapeutic agent is limited. The aim of the present stu
Front Pharmacol. 2025 Nov 10;16:1656751. doi: 10.3389/fphar.2025.1656751. eCollection 2025.ABSTRACTCardiovascular diseases (CVDs) remain the leading cause of death and disability worldwide, highlighting an urgent need for new treatments. Traditional Chinese Medicine (TCM) offers a rich repository of
Front Immunol. 2025 Nov 10;16:1687344. doi: 10.3389/fimmu.2025.1687344. eCollection 2025.ABSTRACTBACKGROUND: Hepatocellular carcinoma (HCC) patients with portal vein tumor thrombus (PVTT) exhibit a dismal prognosis, occurring in 44%-62.2% of cases at initial diagnosis. The optimal treatment for this
Front Immunol. 2025 Nov 10;16:1705866. doi: 10.3389/fimmu.2025.1705866. eCollection 2025.ABSTRACTOBJECTIVE: The aim of this study was to synthesize existing randomized controlled trials (RCTs) to investigate the effects of whole-body vibration (WBV) training on inflammatory markers and lipid profile
