Biomed Pharmacother. 2026 Jun 11;201:119650. doi: 10.1016/j.biopha.2026.119650. Online ahead of print.ABSTRACTIschemic heart disease (IHD) remains a leading cause of morbidity and mortality worldwide. Effective restoration of myocardial perfusion relies on angiogenesis, a process frequently impaired
JACC Adv. 2026 Jun 11;5(7):102882. doi: 10.1016/j.jacadv.2026.102882. Online ahead of print.ABSTRACTBACKGROUND: Medial artery calcification (MAC) is a hallmark of lower extremity artery disease, yet its precise distribution and relationship with intimal artery calcification (IAC) remain poorly under
JACC Adv. 2026 Jun 11;5(7):102870. doi: 10.1016/j.jacadv.2026.102870. Online ahead of print.ABSTRACTBACKGROUND: Performing atrial fibrillation (AF) catheter ablation and percutaneous left atrial appendage occlusion (LAAO) during a single procedure may improve efficiency and reduce cumulative procedu
N Z Med J. 2026 Jun 12;139(1636):87-101. doi: 10.26635/6965.7486.ABSTRACTAIMS: Life expectancy in Aotearoa New Zealand has increased over recent decades, but these increases have not been distributed equally across population groups. Examining how changes in cause-specific mortality have contributed
Europace. 2026 Jun 11:euag144. doi: 10.1093/europace/euag144. Online ahead of print.ABSTRACTBACKGROUND: Disparities in arrhythmia care are increasingly recognised, yet remain incompletely characterised across the patient pathway. This European Heart Rhythm Association (EHRA) survey explored clinicia
Chem Biodivers. 2026 Jun;23(6):e71401. doi: 10.1002/cbdv.71401.ABSTRACTThis study evaluates the antiplatelet potential of Thymelaea tartonraira essential oil, obtained from aerial parts by hydrodistillation. GC-MS analysis identified 43 compounds, with phenethyl alcohol (25.69%), eugenol (12.42%), a
JMIR Cardio. 2026 Jun 11;10:e93036. doi: 10.2196/93036.ABSTRACTBACKGROUND: Atrial fibrillation (AF) is the most common sustained heart rhythm disorder and is a challenging chronic disease to manage. Patients' daily self-care decisions are associated with improved AF outcomes, quality of life, and de
J Med Internet Res. 2026 Jun 11;28:e83302. doi: 10.2196/83302.ABSTRACTBACKGROUND: Sedentary behavior among older adults is a major public health concern, contributing to the increased risk of chronic diseases and functional decline. With aging populations worldwide, prolonged sitting time (averaging
Clin Chem. 2026 Jun 11:hvag051. doi: 10.1093/clinchem/hvag051. Online ahead of print.ABSTRACTBACKGROUND: The clinical application of cardiovascular disease (CVD) biomarkers requires robust biological variation (BV) data to enable both interpretation of serial results and definition of appropriate an
Am J Respir Crit Care Med. 2026 Jun 11:aamag289. doi: 10.1093/ajrccm/aamag289. Online ahead of print.ABSTRACTRATIONALE: While therapeutic advances have improved survival in Group 1 Pulmonary Arterial Hypertension (PAH), patients with Group 1.5 "PAH with features of venous/capillary involvement" (for
Drugs. 2026 Jun 11. doi: 10.1007/s40265-026-02348-4. Online ahead of print.ABSTRACTAtherosclerotic cardiovascular disease (ASCVD) continues to be a leading cause of morbidity and mortality worldwide, with elevated low-density lipoprotein cholesterol (LDL-C) being a major modifiable risk factor. Desp
Transl Stroke Res. 2026 Jun 11;17(3):65. doi: 10.1007/s12975-026-01456-3.ABSTRACTMoyamoya disease (MMD) is a progressive cerebrovascular disorder characterized by abnormal vascular remodeling and impaired angiogenesis. We profiled plasma extracellular vesicle (EV)-derived microRNAs (miRNAs) from MMD
Clin Res Cardiol. 2026 Jun 11. doi: 10.1007/s00392-026-02956-w. Online ahead of print.ABSTRACTBACKGROUND: Transcatheter aortic valve implantation (TAVI) is increasingly performed in patients at low and intermediate risk, emphasizing the need for accurate long-term risk stratification. Although iliof
Cells. 2026 Jun 4;15(11):1034. doi: 10.3390/cells15111034.ABSTRACTCystic Fibrosis Transmembrane Conductance Regulator (CFTR) dysfunction is increasingly recognized as a key contributor to a broad spectrum of human diseases beyond classical cystic fibrosis (CF). CFTR is a cAMP-regulated chloride and
Cells. 2026 May 29;15(11):1001. doi: 10.3390/cells15111001.ABSTRACTMarfan syndrome (MS), Loeys-Dietz syndrome (LDS), Beals-Hecht syndrome (BHS), Ehlers-Danlos syndrome (EDS), and individuals with undifferentiated connective tissue disease (UCTD) exhibit phenotypic overlap, suggesting a likelihood of
Cells. 2026 May 29;15(11):998. doi: 10.3390/cells15110998.ABSTRACTC-reactive protein (CRP) was discovered as a protein that reacts with C-polysaccharides to form precipitates in the serum of patients with pneumococcal infection. Subsequently, it was found to increase in the serum of patients with ba
Cells. 2026 May 25;15(11):973. doi: 10.3390/cells15110973.ABSTRACTSelenium (Se), a vital trace element, plays a significant role in maintaining vascular health and may offer protective effects against atherosclerosis. Its actions are mediated through Se-dependent selenoenzymes and selenoproteins, wh
Biology (Basel). 2026 May 30;15(11):860. doi: 10.3390/biology15110860.ABSTRACTInactive rhomboid protein 2 (iRhom2) regulates ADAM17-mediated shedding of tumor necrosis factor-α (TNF-α) from immune cells. We previously showed that iRhom2 deficiency attenuates early atherosclerosis in mice. This study
Biology (Basel). 2026 May 28;15(11):843. doi: 10.3390/biology15110843.ABSTRACTTo address the heterogeneity in treatment effects (HTE) in precision medicine for coronary heart disease (CHD), we employed an individualized network analysis framework (Pheno-NM) to elucidate the molecular mechanisms of H
Biology (Basel). 2026 May 23;15(11):824. doi: 10.3390/biology15110824.ABSTRACTFerroptosis is an iron-dependent form of regulated cell death driven by lipid peroxidation, playing a critical role in the pathogenesis of various cardiomyopathies, including hypertrophic, dilated, diabetic, ischemic, doxo
JACC Cardiovasc Imaging. 2026 Jun 10:S1936-878X(26)00259-7. doi: 10.1016/j.jcmg.2026.04.015. Online ahead of print.ABSTRACTBACKGROUND: Patients with moderate aortic stenosis (AS) and concomitant mitral regurgitation (MR) often present with symptoms despite neither lesion individually reaching interv
J Clin Invest. 2026 Jun 2:e195507. doi: 10.1172/JCI195507. Online ahead of print.ABSTRACTEnhanced TGFβ signaling caused by mutations in Fibrillin-1 (FBN1) in patients with Marfan syndrome (MFS) leads to myxomatous degeneration of the mitral valve (MDMV). MDMV can result in mitral valve prolapse, sev
Diabetes Care. 2026 Jun 11:dc251738. doi: 10.2337/dc25-1738. Online ahead of print.ABSTRACTOBJECTIVE: To characterize associations of C-peptide measurements with type 1 diabetes (T1D) complications across long-term clinical follow-up in a large representative population cohort (Scottish Diabetes Res
No abstractEur J Prev Cardiol. 2026 Jun 11:zwag318. doi: 10.1093/eurjpc/zwag318. Online ahead of print.NO ABSTRACTPMID:42274373 | DOI:10.1093/eurjpc/zwag318
