Clin Cosmet Investig Dermatol. 2026 Oct 2;19:638098. doi: 10.2147/CCID.S638098. eCollection 2026.ABSTRACTPURPOSE: Psoriasis is associated with systemic comorbidities such as cardiovascular disease. The purpose of this study is to assess whether patients with psoriasis are more likely to also have en
J Mach Learn Res. 2026;27:94.ABSTRACTLinear discriminant analysis is a widely used method for classification. However, the high dimensionality of predictors combined with small sample sizes often results in large classification errors. To address this challenge, it is crucial to leverage data from r
Front Immunol. 2026 Sep 22;17:1830650. doi: 10.3389/fimmu.2026.1830650. eCollection 2026.ABSTRACTExosomes have emerged as important mediators in the pathophysiology of hypertension, facilitating intercellular communication through the transfer of bioactive molecules such as microRNAs. This review sy
Front Cardiovasc Med. 2026 Sep 22;13:1874227. doi: 10.3389/fcvm.2026.1874227. eCollection 2026.ABSTRACTBACKGROUND: The mortality rate from coronary atherosclerotic heart disease is rising year by year, affecting an increasingly younger population, and is projected to continue rising in the future. A
Pulm Circ. 2026 Oct 6;16(4):e70404. doi: 10.1002/pul2.70404. eCollection 2026 Oct.ABSTRACTPulmonary hypertension (PH) is common in patients undergoing transcatheter mitral edge-to-edge repair (M-TEER) and is an established determinant of adverse outcomes after intervention. Importantly, persistent P
Metabol Open. 2026 Sep 24;32:100498. doi: 10.1016/j.metop.2026.100498. eCollection 2026 Dec.ABSTRACTBACKGROUND: The American Heart Association (AHA) introduced the Cardiovascular-Kidney-Metabolic (CKM) syndrome framework, emphasizing the interplay of metabolic risk factors, chronic kidney disease, a
Exp Ther Med. 2026 Sep 14;32(5):302. doi: 10.3892/etm.2026.13297. eCollection 2026 Nov.ABSTRACTThe present study aimed to ascertain the associations between the Life's Essential 8 (LE8) score and metabolic dysfunction-associated steatosis liver disease (MASLD) risk. The PubMed, Scopus and Cochrane l
Front Pain Res (Lausanne). 2026 Sep 22;7:1907108. doi: 10.3389/fpain.2026.1907108. eCollection 2026.ABSTRACTImproved survival in sickle cell disease (SCD) has led to a growing population of older adults who experience a high burden of chronic pain. With aging, pain often shifts from episodic vaso-oc
Front Nutr. 2026 Sep 22;13:1931405. doi: 10.3389/fnut.2026.1931405. eCollection 2026.ABSTRACTRapid global population ageing is accelerating the burden of cardiometabolic disease, and inflammageing-the chronic, low-grade, sterile inflammation that accompanies advancing age-has emerged as a shared pat
Clin Interv Aging. 2026 Oct 2;21:626483. doi: 10.2147/CIA.S626483. eCollection 2026.ABSTRACTAlzheimer's disease (AD) is a progressive neurodegenerative disorder and a growing public health concern. Its core pathological features include cerebral amyloid-β deposition and tau aggregation. mRNA transla
Front Neurol. 2026 Sep 22;17:1912737. doi: 10.3389/fneur.2026.1912737. eCollection 2026.ABSTRACTPost-stroke cognitive impairment (PSCI) is a common and debilitating neurological complication following cerebral ischemia-reperfusion injury (CIRI). The traditional neuron-centered view cannot fully expl
Front Neurol. 2026 Sep 22;17:1951552. doi: 10.3389/fneur.2026.1951552. eCollection 2026.ABSTRACTThis structured narrative review evaluates endovascular thrombectomy (EVT) through an author-developed, population-level treatment-response framework. In this framework, treatment response is the causal c
Front Neurol. 2026 Sep 22;17:1946268. doi: 10.3389/fneur.2026.1946268. eCollection 2026.ABSTRACTStroke disproportionately affects Africa, where incidence and prevalence rates rank among the highest reported worldwide, and case-fatality remains high. As acute survival improves in many, though not all
Front Immunol. 2026 Sep 22;17:1976141. doi: 10.3389/fimmu.2026.1976141. eCollection 2026.ABSTRACTDiabetic cardiac remodeling involves microvascular dysfunction, inflammatory myeloid responses and fibroblast activation. O-linked beta-N-acetylglucosamine (O-GlcNAc) modification connects nutrient metab
Sage Open Chronic Dis. 2026 Mar 27;17:27558428261421490. doi: 10.1177/27558428261421490. eCollection 2026 Jan-Dec.ABSTRACTBACKGROUND: Thyroid disease is a type of endocrinologic disease that should be treated early to avoid thyroid disease-related comorbidities, especially cardiovascular complicatio
JMA J. 2026 Sep 15;9(5):1187-1195. doi: 10.31662/jmaj.2025-0554. Epub 2026 May 29.ABSTRACTINTRODUCTION: Spironolactone (SPL) is a steroidal mineralocorticoid receptor antagonist (MRA) that binds non-specifically to sex hormone receptors. Given the role of sex hormones in sleep regulation, SPL may po
Cureus. 2026 Sep 5;18(9):e115840. doi: 10.7759/cureus.115840. eCollection 2026 Sep.ABSTRACTChronic kidney disease (CKD) is a major global health concern characterized by progressive loss of kidney function and an increased risk of cardiovascular morbidity and mortality. Sodium-glucose cotransporter-
Exp Ther Med. 2026 Sep 11;32(5):300. doi: 10.3892/etm.2026.13295. eCollection 2026 Nov.ABSTRACTCardiovascular diseases (CVD) are among the leading causes of mortality worldwide and accurate diagnosis is important for treatment and prognosis. The present study intended to develop a model for diagnosi
JMA J. 2026 Sep 15;9(5):1350-1359. doi: 10.31662/jmaj.2026-0201. Epub 2026 Jul 31.ABSTRACTINTRODUCTION: The ENABLE study demonstrated comparable survival benefits between enzalutamide (ENZ) and abiraterone plus prednisolone (ABI) in castration-resistant prostate cancer (CRPC). Although the associati
Public Health Chall. 2026 Oct 5;5(4):e70410. doi: 10.1002/puh2.70410. eCollection 2026 Dec.ABSTRACTOne of Ghana's most significant yet under-recognized public health issues is hypertension, which is driving, increases in cardiovascular disease, disability and premature mortality. Despite ongoing imp
Front Endocrinol (Lausanne). 2026 Sep 22;17:1987603. doi: 10.3389/fendo.2026.1987603. eCollection 2026.ABSTRACTDiabetic cardiomyopathy (DCM) is characterized by mitochondrial metabolic inflexibility, redox imbalance and defective organelle quality control, yet the endocrine program coordinating thes
EClinicalMedicine. 2026 Sep 28;100:104202. doi: 10.1016/j.eclinm.2026.104202. eCollection 2026 Oct.ABSTRACTBACKGROUND: Tetanus is a life-threatening, vaccine-preventable disease. Its incidence decreased substantially following global initiatives such as the Expanded Programme on Immunization (EPI) a
Front Cell Dev Biol. 2026 Sep 22;14:1926050. doi: 10.3389/fcell.2026.1926050. eCollection 2026.ABSTRACTPlatelet-derived growth factor-BB (PDGF-BB), a core functional isoform of the PDGF family, serves as a central regulator of cell proliferation, migration, differentiation, and tissue remodeling. Ex
Front Pharmacol. 2026 Sep 22;17:1747506. doi: 10.3389/fphar.2026.1747506. eCollection 2026.ABSTRACTBACKGROUND: Current guidelines advise against routine use of parenteral anticoagulation therapy (PACT) for ST-segment elevated myocardial infarction (STEMI) patients after percutaneous coronary interve
