Urolithin A has antiplatelet effects in contrast to its glucuronide, urolithin B, and isourolithin A

Front Cardiovasc Med. 2026 Sep 15;13:1843932. doi: 10.3389/fcvm.2026.1843932. eCollection 2026.ABSTRACTINTRODUCTION: Consumption of dietary ellagitannins has been suggested to have protective effects against cardiovascular disease, likely due to the colonic formation of urolithins and their subseque

A Alina Soloviova

Case Report: Ischemic central retinal vein occlusion in a patient with relapsed mantle cell lymphoma as a manifestation of suspected cancer-associated hypercoagulability

Front Med (Lausanne). 2026 Sep 15;13:1926148. doi: 10.3389/fmed.2026.1926148. eCollection 2026.ABSTRACTBACKGROUND: Ischemic central retinal vein occlusion (ischemic CRVO) is a severe, vision-threatening vascular event. While most cases stem from conventional cardiovascular or local anatomical etiolo

C Chaoxiong Cui

Transcriptomics-based analysis of muscle injury mechanism mediated by inflammatory imbalance in the Duchenne muscular dystrophy muscle microenvironment

Front Neurol. 2026 Sep 15;17:1905030. doi: 10.3389/fneur.2026.1905030. eCollection 2026.ABSTRACTBACKGROUND: Duchenne muscular dystrophy (DMD) is a hereditary neuromuscular disease characterized by progressive myofiber injury, chronic inflammatory response, and persistent fibrotic remodeling, for whi

C Chunhui Shan

Long-term mental health and quality of life in patients after cervical artery dissection

Front Neurol. 2026 Sep 15;17:1726823. doi: 10.3389/fneur.2026.1726823. eCollection 2026.ABSTRACTINTRODUCTION: Most patients with Cervical Artery Dissection (CeAD) experience good long-term functional outcome. Little is known about long-term psychological sequelae in these patients.PATIENTS AND METHO

K Katrine Sværke

Impaired antigen clearance of macrophages associates with heart failure and non-obstructive azoospermia: insights from transcriptomics, in silico knockout, and in vitro validation

Front Immunol. 2026 Sep 15;17:1909437. doi: 10.3389/fimmu.2026.1909437. eCollection 2026.ABSTRACTBACKGROUND: Heart failure (HF) and non-obstructive azoospermia (NOA) are high-burden diseases that share chronic inflammation and tissue injury. Macrophages are key regulators in both conditions, yet whe

Z Zheng Zhao

Biochemical and renal-metabolic profiles distinguishing primary aldosteronism from essential hypertension: a systematic review and meta-analysis with implications for endocrine hypertension screening

Front Endocrinol (Lausanne). 2026 Sep 15;17:1916237. doi: 10.3389/fendo.2026.1916237. eCollection 2026.ABSTRACTINTRODUCTION: To characterize electrolyte and renal-metabolic profiles in primary aldosteronism (PA) compared with essential hypertension (EH), and to examine differences between unilateral

X Xuan Zhao

GA Eases Atherosclerosis by Regulating Circadian Rhythm

Pharmazie. 2026 Sep 18;81(9):55101. doi: 10.31083/Pharmazie55101.ABSTRACTBACKGROUND: Atherosclerosis (AS) serves as a fundamental high-risk factor associated with the development of cardiovascular diseases. There is an urgent need to investigate efficacious therapeutic strategies and molecular targe

C Chengxin Hao

Lipid Metabolism, Statins and Bleeding Risk During Anticoagulant Therapy: Emerging Pharmacological Insights

Pharmazie. 2026 Sep 18;81(9):54718. doi: 10.31083/Pharmazie54718.ABSTRACTLipid metabolism, coagulation, inflammation, and vascular integrity are closely interconnected biological systems. Although statins are primarily prescribed to reduce low-density lipoprotein cholesterol (LDL-C) and prevent athe

C Carmine Siniscalchi

Hydroxysafflor Yellow A Alleviates Ischemic Stroke Through Modulation of GPX4-Associated Ferroptosis: Computational Simulation and Animal Validation

Pharmazie. 2026 Sep 18;81(9):55314. doi: 10.31083/Pharmazie55314.ABSTRACTBACKGROUND: Ferroptosis has been recognized as an important pathological mechanism underlying ischemic stroke (IS). However, the precise mechanisms underlying the neuroprotective effects of Hydroxysafflor yellow A (HSYA) in IS

Y Yun Chen

An Algorithm for Inferior Vena Cava Filter Placement in Severely Injured Patients: A Systematic Review-Based Consensus and Guidelines by SMA-VS

Br J Hosp Med (Lond). 2026 Sep 10;87(9):55548. doi: 10.31083/BJHM55548.ABSTRACTAIMS/BACKGROUND: Venous thromboembolism is a major complication of severe injury, and the role of inferior vena cava (IVC) filters in patients suffering from this condition remains controversial. The current clinical prac

B Biyu Rui

Risk Factor Analysis of Cardiovascular Events in Patients With Diabetic Kidney Disease and Hypertension: A Retrospective Study

Br J Hosp Med (Lond). 2026 Sep 15;87(9):49746. doi: 10.31083/BJHM49746.ABSTRACTAIMS/BACKGROUND: Diabetic kidney disease (DKD) is among the most prevalent complications of diabetes and is commonly accompanied by hypertension as a comorbid condition. The coexistence of these two conditions markedly au

X Xiaofen Sun

Predictors of Functional Recovery in Patients With Mild Hemorrhagic Transformation Following Intravenous Thrombolysis for Acute Ischemic Stroke

Br J Hosp Med (Lond). 2026 Sep 18;87(9):50688. doi: 10.31083/BJHM50688.ABSTRACTAIMS/BACKGROUND: Patients who develop mild hemorrhagic transformation (HT) after intravenous thrombolysis (IVT) for acute ischemic stroke (AIS) exhibit substantial heterogeneity in functional recovery. However, a systemat

S Shengxiong Pu

Long-Term Protective Association of Elevated Body Mass Index With Survival in Intracerebral Hemorrhage: A 2-Year Cohort Study Revealing the Obesity Paradox

Br J Hosp Med (Lond). 2026 Sep 21;87(9):58250. doi: 10.31083/BJHM58250.ABSTRACTAIMS/BACKGROUND: The 'obesity paradox' has been reported in intracerebral hemorrhage (ICH), but evidence on long-term mortality remains limited. We investigated the association between body mass index (BMI) and long-term

Y Yu Deng

The Efficacy of Different Exercise Intervention Models and Dosages on Post-Stroke Depression: A Systematic Review and Network Meta-Analysis

Br J Hosp Med (Lond). 2026 Sep 21;87(9):58254. doi: 10.31083/BJHM58254.ABSTRACTAIMS/BACKGROUND: Post-stroke depression (PSD) is a prevalent psychological complication among stroke survivors. Exercise intervention, as a non-pharmacological therapeutic approach, plays a crucial role in the rehabilitat

X Xiaolu Fan

GLP-1 Receptor Agonists in Diabetic Lower Extremity Peripheral Artery Disease: From Mechanisms to Clinical Practice

Br J Hosp Med (Lond). 2026 Sep 22;87(9):55884. doi: 10.31083/BJHM55884.ABSTRACTDiabetic lower extremity peripheral artery disease (PAD) is a complex and multifactorial complication of diabetes mellitus, characterized by extensive distal disease burden, accelerated progression, and a markedly elevate

J Jie Pan

Clinical Benefit of the Transthyretin Stabiliser Tafamidis in Hereditary Transthyretin Amyloid Cardiomyopathy: A Case Report

Br J Hosp Med (Lond). 2026 Sep 22;87(9):58285. doi: 10.31083/BJHM58285.ABSTRACTAIMS/BACKGROUND: This case report aims to illustrate the critical importance of a standardized diagnostic approach and genotype-specific therapy in hereditary transthyretin amyloid cardiomyopathy (ATTR-CM). It highlights

X Xing Xiao

Plasma metabolomics combined with machine learning for classifying ischemic stroke subtypes and predicting the etiology of cryptogenic stroke

Nan Fang Yi Ke Da Xue Xue Bao. 2026 Sept 20;46(9):2149-2158. doi: 10.12122/j.issn.1673-4254.2026.09.14.ABSTRACTOBJECTIVES: To analyze plasma metabolic profiles of different ischemic stroke subtypes and construct machine learning (ML)-based models to identify these subtypes for accurate diagnosis of

Y Yinyu Zi

Genistein alleviates cerebral ischemia/reperfusion-induced inflammatory injury in rats by regulating microglial polarization via the PI3K/AKT/COX-2 signaling pathway

Nan Fang Yi Ke Da Xue Xue Bao. 2026 Sept 20;46(9):2130-2148. doi: 10.12122/j.issn.1673-4254.2026.09.13.ABSTRACTOBJECTIVES: To investigate the mechanism of genistein for alleviating cerebral ischemia/reperfusion (I/R)-induced neuroinflammation in microglia and its protective effects on co-cultured ne

M Mengjia Li

Reverse Cascade Genetic Screening for Revealing New Cases of Familial Hypercholesterolemia in Russia: Pilot Project

Front Biosci (Schol Ed). 2026 Aug 31;18(3):47474. doi: 10.31083/FBS47474.ABSTRACTBACKGROUND: Reverse cascade genetic screening, following initial lipid testing, is an effective strategy for the early diagnosis of familial hypercholesterolemia (FH) and related hereditary dyslipidemias. In this study,

V Valentina V Miroshnikova

Next Generation Sequencing in the Diagnosis of Multiple Myeloma

Front Biosci (Schol Ed). 2026 Sep 4;18(3):44690. doi: 10.31083/FBS44690.ABSTRACTMultiple myeloma (MM) is a biologically and clinically heterogeneous plasma cell malignancy characterized by clonal expansion in the bone marrow and a highly variable clinical course. Despite major therapeutic advances,

I Ikram El Fazazi

Factors Influencing Health Behavior Adherence in Young and Middle-Aged Stroke Patients

Rev Neurol. 2026 Sep 2;81(9):51282. doi: 10.31083/RN51282.ABSTRACTBACKGROUND: Health behavior adherence (HBA) is important for effective rehabilitation and secondary prevention after stroke. Young and middle-aged patients may face particular challenges in maintaining recommended health behaviors dur

Q Qiaohui Ye

Association of Short-Course Methylprednisolone Therapy With Early Composite Imaging Abnormalities in Patients With Early Neurological Deterioration After Endovascular Thrombectomy for Acute Ischemic Stroke

Rev Neurol. 2026 Sep 22;81(9):54438. doi: 10.31083/RN54438.ABSTRACTBACKGROUND: Early neurological deterioration (END) after endovascular thrombectomy (EVT) may be accompanied by heterogeneous postprocedural imaging abnormalities. We investigated the association between short-course methylprednisolon

C Changsi Ai

Heart Failure: Lipid Metabolism Disorders Driving Cellular Senescence Through a Vicious Cycle, and Possible Intervention Strategies

Front Biosci (Landmark Ed). 2026 Aug 31;31(9):48959. doi: 10.31083/FBL48959.ABSTRACTHeart failure (HF) is major and growing global health challenge, with lipid metabolism dysregulation recognized as a significant contributing factor. This review focuses on the emerging concept of the "metabolism-sen

W Wei He

Mechanisms of Complement Activation and NETosis Interplay in Early Pregnancy Loss: From Autoimmunity to Thrombogenesis

Front Biosci (Landmark Ed). 2026 Aug 31;31(9):49518. doi: 10.31083/FBL49518.ABSTRACTEarly Pregnancy Loss (EPL) represents a formidable challenge in reproductive medicine. Its complex pathophysiology is primarily characterized by dysregulation of both the immune and coagulation systems. In recent yea

J Junxian Ma