Am J Physiol Regul Integr Comp Physiol. 2026 May 14. doi: 10.1152/ajpregu.00040.2026. Online ahead of print.ABSTRACTSex is increasingly recognized as a critical biological variable in preclinical cardiovascular research yet baseline physiological differences between male and female animals-and the e
JAMA Netw Open. 2026 May 1;9(5):e266783. doi: 10.1001/jamanetworkopen.2026.6783.ABSTRACTIMPORTANCE: Adverse pregnancy outcomes (APOs) confer risk for maternal cardiovascular disease, but the role of APOs in cardiovascular health (CVH) of offspring across the life course is unknown.OBJECTIVE: To exam
JAMA Netw Open. 2026 May 1;9(5):e2612823. doi: 10.1001/jamanetworkopen.2026.12823.ABSTRACTIMPORTANCE: Early identification of cardiovascular-kidney-metabolic (CKM) syndrome is essential for preventing subsequent organ failure. While atrial fibrillation (AF) is often incidentally detected in working-
Drugs. 2026 May 14. doi: 10.1007/s40265-026-02337-7. Online ahead of print.ABSTRACTLupus nephritis (LN) remains a major cause of morbidity and progression to chronic kidney disease in systemic lupus erythematosus. Beyond immunosuppression, emerging evidence highlights the critical role of nephron-pr
J Mol Neurosci. 2026 May 14;76(2):84. doi: 10.1007/s12031-026-02513-0.ABSTRACTThis study aimed to evaluate the impact of prior pregnancy on hippocampal brain-derived neurotrophic factor (BDNF) levels and behavioral recovery following focal cerebral ischemia in female Wistar rats, exploring pregnancy
Insights Imaging. 2026 May 14;17(1):129. doi: 10.1186/s13244-026-02264-x.ABSTRACTThere are well-established and widely accepted criteria for determining the presence of excessive myocardial trabeculation (ET) in the left ventricle in patients undergoing cardiac imaging studies. ET has been documente
Mol Biol Rep. 2026 May 14;53(1):769. doi: 10.1007/s11033-026-11922-8.ABSTRACTDespite major advances in medicine, cancer treatment remains a considerable challenge. The rising incidence of new cases and the frequent resistance to cytostatics suggest that standard therapies may be insufficient. This h
Mol Biol Rep. 2026 May 14;53(1):765. doi: 10.1007/s11033-026-11951-3.ABSTRACTBACKGROUND: Hypercholesterolemia is a common metabolic disorder characterized by elevated low-density lipoprotein cholesterol (LDL-C) levels, a major risk factor for cardiovascular disease. MicroRNAs (miRNAs) are key post-t
Support Care Cancer. 2026 May 14;34(6):541. doi: 10.1007/s00520-026-10774-z.ABSTRACTPURPOSE: Anthracycline-induced cardiotoxicity is dose-dependent, yet guidelines provide inconsistent cumulative dose thresholds and few standards for converting doses when multiple agents are used. Moreover, no forma
Eur J Pediatr. 2026 May 14;185(6):392. doi: 10.1007/s00431-026-07068-1.ABSTRACTPrimary ciliary dyskinesia (PCD) is a rare genetic disorder that may result in progressive lung damage. The Specific PCD Evaluation by CT (SPEC) scoring system has been specifically used in PCD patients since 2024. This s
Naunyn Schmiedebergs Arch Pharmacol. 2026 May 14. doi: 10.1007/s00210-026-05416-4. Online ahead of print.ABSTRACTDespite optimal lipid-lowering treatment, numerous older adults with atherosclerotic cardiovascular disease continue to experience progression driven by inflammation, referred to as resid
Eur J Clin Pharmacol. 2026 May 14;82(6):152. doi: 10.1007/s00228-026-04050-6.ABSTRACTPURPOSE: Gliflozins (SGLT2 inhibitors) and statins are key treatments commonly used in patients with ischemic heart failure. Although both are well known for diminishing cardiovascular risk and heart failure-related
Am J Physiol Heart Circ Physiol. 2026 May 14. doi: 10.1152/ajpheart.00123.2026. Online ahead of print.ABSTRACTStudy Objectives: Chronic short sleep duration is associated with cardiovascular disease (CVD) risk, especially in females. The impact of biological sex on hemodynamic reactivity to spontane
Eur J Cardiovasc Nurs. 2026 May 14:zvag098. doi: 10.1093/eurjcn/zvag098. Online ahead of print.ABSTRACTAIMS: The FRAIL scale questionnaire is a brief measure of physical frailty in patients with cardiovascular disease (CVD); however, its performance in those with concomitant cognitive impairment rem
Trends Hear. 2026 Jan-Dec;30:23312165261446384. doi: 10.1177/23312165261446384. Epub 2026 May 14.ABSTRACTAccurate sound localization relies on the transformation of binaural cues into stable spatial representations, yet the neural mechanisms supporting this process remain incompletely understood. Mi
Mycoses. 2026 May;69(5):e70173. doi: 10.1111/myc.70173.ABSTRACTAIM: Metamizole is an analgesic drug with moderate cytochrome P450 (CYP) inductive properties. The antifungal triazoles are metabolized by several CYP enzymes, but the interaction with metamizole remains poorly described. We investigated
Nanoscale Horiz. 2026 May 13. doi: 10.1039/d5nh00795j. Online ahead of print.ABSTRACTMicro/nanorobots have attracted much attention because of their potential to perform complex tasks with high precision under controlled actuation within the human body, such as targeted cargo delivery, lesion explor
J Immunother. 2026 Jun 1;49(5):209-213. doi: 10.1097/CJI.0000000000000589.ABSTRACTTo examine the clinical characteristics of sintilimab-induced myocarditis and to provide evidence for its diagnosis and management. Retrospective analysis was conducted on clinical case reports of sintilimab-induced my
JACC Case Rep. 2026 May 13:108056. doi: 10.1016/j.jaccas.2026.108056. Online ahead of print.ABSTRACTBACKGROUND: Guidewire-induced pseudostenosis, or the "accordion effect," can mimic true arterial occlusion during percutaneous coronary intervention, particularly in tortuous vessels.CASE SUMMARY: A 6
JACC Case Rep. 2026 May 13:108247. doi: 10.1016/j.jaccas.2026.108247. Online ahead of print.ABSTRACTBACKGROUND: Recurrent pericarditis (RP) is a clinical condition managed with anti-inflammatory medications, with a subset of patients developing overt constriction requiring pericardiectomy.CASE SUMMA
JACC Case Rep. 2026 May 14:108345. doi: 10.1016/j.jaccas.2026.108345. Online ahead of print.ABSTRACTBACKGROUND: Anaphylaxis is a severe hypersensitivity reaction that may involve the heart through overlapping inflammatory, vascular, and catecholaminergic mechanisms. The ATAK (adrenaline, Takotsubo c
JACC Case Rep. 2026 May 14:108311. doi: 10.1016/j.jaccas.2026.108311. Online ahead of print.ABSTRACTBACKGROUND: Microvascular dysfunction may persist despite successful primary percutaneous coronary intervention (PCI) in anterior ST-segment elevation myocardial infarction (STEMI). Supersaturated oxy
JACC Case Rep. 2026 May 14:108321. doi: 10.1016/j.jaccas.2026.108321. Online ahead of print.ABSTRACTBACKGROUND: Trabectedin is a marine-derived alkylating agent used to treat soft tissue sarcomas.CASE SUMMARY: We present a case of myocardial infarction with nonobstructive coronary arteries (MINOCA)
JACC Case Rep. 2026 May 14:108361. doi: 10.1016/j.jaccas.2026.108361. Online ahead of print.ABSTRACTBACKGROUND: Bitter orange (Citrus aurantium) is a common ingredient in weight-loss supplements and contains p-synephrine, a proto-alkaloid with sympathomimetic properties. Various cardiovascular adver
