Effect of empagliflozin on copeptin levels in patients with recent acute coronary syndrome and newly detected dysglycaemia: a post-hoc analysis of the SOCOGAMI randomized controlled trial

Cardiovasc Diabetol. 2026 Jul 28;25(1):212. doi: 10.1186/s12933-026-03312-y.ABSTRACTBACKGROUND: Copeptin, a surrogate marker for vasopressin secretion, is associated with cardiovascular disease, insulin resistance and dysglycaemia. The cardioprotective effects of sodium-glucose cotransporter 2 inhib

E Elena Fortin

Identification of pulmonary hypertension with pulmonary vascular surface volume ratio by non-contrast CT

BMC Cardiovasc Disord. 2026 Jul 28;26(1):641. doi: 10.1186/s12872-026-06078-z.ABSTRACTBACKGROUND: The diagnosis of pulmonary hypertension (PH) relies primarily on invasive right heart catheterization (RHC). Although imaging modalities, including echocardiography, computed tomography angiography (CTA

Q Qing Yu

Barriers to physical activity in patients with systemic lupus erythematosus in the UK

Clin Rheumatol. 2026 Jul 28. doi: 10.1007/s10067-026-08324-3. Online ahead of print.ABSTRACTINTRODUCTION: Physical activity (PA) may play an important role as a non-pharmacological addition to the management of SLE for disease control and reduction of cardiovascular risk factors. Those with SLE have

A Aliaksandra Baranskaya

GLP-1 receptor agonists at the crossroads of diabetes, hepatic steatosis, and hepatocellular carcinoma

Intern Emerg Med. 2026 Jul 28. doi: 10.1007/s11739-026-04456-1. Online ahead of print.ABSTRACTThe epidemiology of hepatocellular carcinoma (HCC) is increasingly shaped by the expanding burden of type 2 diabetes (T2D), obesity, and metabolic dysfunction-associated steatotic liver disease (MASLD). Glu

A Alfredo Vozza

Joint effects of social determinants of health on NAFLD mortality: the mediating role of phenotypic age acceleration

Geroscience. 2026 Jul 28. doi: 10.1007/s11357-026-02439-w. Online ahead of print.ABSTRACTAlthough individual social determinants of health (SDoH) are known to influence non-alcoholic fatty liver disease (NAFLD) outcomes, the cumulative effect of comprehensive SDoH exposure and the underlying biologi

X Xingyong Huang

Association Between Zinc-to-Copper Ratio and Hypertension in Populations with Differential Environmental Heavy Metal Exposure

Biol Trace Elem Res. 2026 Jul 29. doi: 10.1007/s12011-026-05262-8. Online ahead of print.ABSTRACTThe zinc-to-copper ratio (ZCR) reflects essential metal balance and may be relevant to cardiovascular regulation, yet its association with hypertension in populations exposed to environmental heavy metal

S Sang-Yong Eom

Pericoronary fat radiomics on coronary CT angiography for predicting major adverse cardiac events: a systematic review and meta-analysis

Eur Radiol. 2026 Jul 28. doi: 10.1007/s00330-026-12778-z. Online ahead of print.ABSTRACTBACKGROUND: Pericoronary adipose tissue (PCAT) reflects local coronary inflammation and microstructural changes and may predict major adverse cardiac events (MACE). Radiomics extracts high-dimensional features fr

S Seyedeh-Tarlan Mirzohreh

Sequencing-free spatial profiling of post-transcriptional regulation in fresh tissues using nanoneedle arrays

Nat Biomed Eng. 2026 Jul 28. doi: 10.1038/s41551-026-01745-0. Online ahead of print.ABSTRACTSpatial transcriptomics has transformed tissue analysis but remains constrained by high cost, complex workflows, sequencing dependence and limited access to post-transcriptional regulation in fresh tissues. H

X Xianglin Ji

Nuclear class 3 PI3K co-activates fasting-specific chromatin remodelling

Nat Cell Biol. 2026 Jul 28. doi: 10.1038/s41556-026-02030-7. Online ahead of print.ABSTRACTTranscriptional remodelling during fasting ensures metabolic adaptation and provides health benefits across species. Although several regulators of fasting-induced transcription and chromatin are known, how nu

N Nathaniel F Henneman

Deficiency of the aryl hydrocarbon receptor in kidney epithelial cells does not influence the development of atherosclerosis

Sci Rep. 2026 Jul 29;16(1):23537. doi: 10.1038/s41598-026-63808-1.ABSTRACTThe aryl hydrocarbon receptor (AHR) is recognised as an important mediator of inflammatory processes, including those in kidney health. Patients suffering from kidney diseases have an increased risk of cardiovascular diseases,

R Rosanna Huchzermeier

Mitochondrial quality control in health and disease: mechanisms and therapeutic targets

Signal Transduct Target Ther. 2026 Jul 29;11(1):295. doi: 10.1038/s41392-026-02813-2.ABSTRACTMitochondria are essential for cellular homeostasis, integrating various signals to control key cellular functions such as metabolism, apoptosis, inflammation, cell proliferation and redox balance. Given the

A Agustina Creus

Racial and ethnic disparities in the cause of death for clear cell renal cell carcinoma

Nat Commun. 2026 Jul 28;17(1):7553. doi: 10.1038/s41467-026-70709-4.ABSTRACTThe trends and contributors of racial and ethnic disparities in causes of death among patients with clear cell renal cell carcinoma remain unclear. We analyse SEER data (2000-2019) and find that Black patients have the highe

Y Yingwei Xie

Cardiovascular Autonomic Neuropathy and Indices of Heart Failure in Type 2 Diabetes: The CANCAN Study

Diabetes Obes Metab. 2026 Jul 28. doi: 10.1111/dom.71100. Online ahead of print.ABSTRACTAIM: To quantify the association between cardiovascular autonomic neuropathy (CAN) and heart failure (HF) in individuals with type 2 diabetes (T2D).MATERIALS AND METHODS: Two hundred T2D individuals were recruite

J Jonas R Schaarup

Artificial intelligence for interstitial lung disease pattern recognition on high-resolution computed tomography: A step forward for general radiologists

No abstractDiagn Interv Imaging. 2026 Jul 28:S2211-5684(26)00131-2. doi: 10.1016/j.diii.2026.07.004. Online ahead of print.NO ABSTRACTPMID:42521552 | DOI:10.1016/j.diii.2026.07.004

C Chiara Pozzessere

Emerging therapies to lower lipoprotein(a) and the current clinical trials landscape: RNA-therapeutics and beyond

J Clin Lipidol. 2026 Jul 3:S1933-2874(26)00425-3. doi: 10.1016/j.jacl.2026.06.025. Online ahead of print.ABSTRACTBACKGROUND: Lipoprotein(a) [Lp(a)] is a genetically determined, independent risk factor for atherosclerotic cardiovascular disease (ASCVD) and calcific aortic valve disease. Currently, th

S Sawye Raygani

Investigating Novel Inflammatory Biomarkers and Pathways in Cardiac Cachexia

Heart Lung Circ. 2026 Jul 28:S1443-9506(26)00215-5. doi: 10.1016/j.hlc.2026.03.064. Online ahead of print.ABSTRACTBACKGROUND: Cardiac cachexia (CC) is an indicator of advanced heart failure (AHF), with significant unintentional weight loss (UWL) and poor prognosis. Its diagnostic criteria incorporat

M Mansimran Singh Dulay

Impact of systemic diseases on periodontal remodeling: Mechanisms, mediators, and clinical relevance

Periodontol 2000. 2026 Jul 28. doi: 10.1111/prd.70048. Online ahead of print.ABSTRACTBACKGROUND: Periodontal remodeling is a continuous, adaptive process essential for maintaining the structural and functional integrity of periodontal tissues. While external factors such as bacterial biofilm, excess

M Michael Wolf

A Cerebral Organoid Model of Familial Alzheimer's Disease Using Amyloid Precursor Protein Mutation, Val669Leu (APP(Seoul))

Int J Stem Cells. 2026 Jul 29. doi: 10.15283/ijsc25044. Online ahead of print.ABSTRACTVarious animal and cellular Alzheimer's disease (AD) models harboring familial AD (fAD) mutations have been developed and widely used for AD research. In this study, we established an AD cerebral organoid (CO) mode

W Won Hee Jung

Non-communicable disease prevalence among asylum seekers and Swiss nationals: a comparative cross-sectional study in emergency care

Emerg Med J. 2026 Jul 28:emermed-2025-215662. doi: 10.1136/emermed-2025-215662. Online ahead of print.ABSTRACTBACKGROUND: Non-communicable diseases (NCDs) are the leading causes of death worldwide. Ongoing global migration increases the proportion of recently arrived migrants in many countries. Yet

A Anne Jachmann

Micro-axial flow pump vs veno-arterial extracorporeal membrane oxygenation for high-risk percutaneous coronary interventions: a randomized trial

Eur Heart J. 2026 Jul 29:ehag520. doi: 10.1093/eurheartj/ehag520. Online ahead of print.ABSTRACTBACKGROUND AND AIMS: The efficacy of prophylactic mechanical circulatory support with micro-axial flow pump or veno-arterial extracorporeal membrane oxygenation (VA-ECMO) in patients with severely reduced

G Gang Zhao

Cardiovascular health as an unmet priority in addiction medicine: Implications of recent cardiovascular strategies

Addiction. 2026 Jul 28. doi: 10.1111/add.70562. Online ahead of print.ABSTRACTAIMS: To examine how recent cardiovascular strategies that emphasise mental health, psychosocial vulnerability, equity and integrated care expose a major and under-addressed gap in addiction medicine: the limited integrati

J Jose Seijas-Amigo

Effects of ursodeoxycholic acid on statin-induced impaired glucose tolerance: study protocol for a randomized controlled trial

BMJ Open. 2026 Jul 28;16(7):e117417. doi: 10.1136/bmjopen-2026-117417.ABSTRACTINTRODUCTION: Statin therapy is associated with an increased risk of dysglycaemia and new-onset type 2 diabetes, which compromises patient adherence. Ursodeoxycholic acid (UDCA), a hepatoprotective drug, has shown potentia

Y Yue Yu

Renin-angiotensin system blockade in diabetic kidney disease: an old pillar that still stands at the core of therapy

Kidney Res Clin Pract. 2026 Jul 28. doi: 10.23876/j.krcp.26.225. Online ahead of print.ABSTRACTDiabetic kidney disease (DKD) is the leading cause of chronic kidney disease and end-stage kidney disease worldwide. Activation of the renin-angiotensin system (RAS) plays a central role in the pathogenesi

D Dong Hoon Kang

Sodium-glucose cotransporter 2 inhibitors in diabetic kidney disease

Kidney Res Clin Pract. 2026 Jul 28. doi: 10.23876/j.krcp.26.139. Online ahead of print.ABSTRACTDiabetic kidney disease (DKD) is a major contributor to chronic kidney disease (CKD) and end-stage kidney disease worldwide, and is strongly associated with increased cardiovascular morbidity and mortality

D Da Woon Kim