Can J Physiol Pharmacol. 2026 Jan 1;104:1-14. doi: 10.1139/cjpp-2026-0173.ABSTRACTCardiovascular diseases (CVDs) are one of the leading causes of mortality worldwide, with myocardial infarction (MI) resulting in irreversible loss of cardiomyocytes and progressive cardiac dysfunction. Clinical interv
Aging Cell. 2026 Oct;25(10):e70765. doi: 10.1111/acel.70765.ABSTRACTHutchinson-Gilford progeria syndrome (HGPS) is a rare premature aging disorder most commonly caused by a de novo synonymous mutation (c.1824C>T) in the LMNA gene. This mutation activates aberrant splicing of prelamin A, leading to t
Clin Sci (Lond). 2026 Nov 11;140(11):2363-2385. doi: 10.1042/CS20250834.ABSTRACTImmune cell function is tightly coupled to cellular metabolism, with glycolysis, oxidative phosphorylation, and amino acid and lipid metabolism governing activation, differentiation, survival, and effector responses. In
Clin Cardiol. 2026 Oct;49(10):e70498. doi: 10.1002/clc.70498.ABSTRACTBACKGROUND: Valvular heart disease, particularly aortic stenosis (AS), often remains asymptomatic until advanced stages, making early detection challenging. Although cardiac auscultation is a traditional screening tool, its diagnos
J Clin Invest. 2026 Oct 15;136(20):e211265. doi: 10.1172/JCI211265. eCollection 2026 Oct 15.ABSTRACTEfferocytosis, or the clearance of apoptotic cells by macrophages, has been implicated in tissue resolution that promotes disease regression in atherosclerosis and other diseases of chronic inflammati
Arterioscler Thromb Vasc Biol. 2026 Oct 15. doi: 10.1161/ATVBAHA.126.325434. Online ahead of print.ABSTRACTBACKGROUND: Adult mammalian cardiomyocytes exhibit some capacity to reenter the cell cycle after ischemic injury. However, activated cardiomyocytes rapidly undergo cell cycle rearrest shortly a
Arterioscler Thromb Vasc Biol. 2026 Oct 15. doi: 10.1161/ATVBAHA.126.324811. Online ahead of print.ABSTRACTCardiometabolic diseases are a leading cause of global morbidity and mortality and arise from shared and distinct risk factors acting through interconnected biological pathways. Although excess
Arterioscler Thromb Vasc Biol. 2026 Oct 15. doi: 10.1161/ATVBAHA.126.324762. Online ahead of print.ABSTRACTCardiovascular imaging plays a central role in the diagnosis, risk stratification, and management of cardiovascular disease, yet the complexity and volume of imaging data increasingly exceed th
J Clin Pharmacol. 2026 Oct;66(10):e70312. doi: 10.1002/jcph.70312.ABSTRACTConcentration-QTc analysis from Phase 1 studies is increasingly used to evaluate QTc prolongation risk as an alternative to thorough QT (TQT) studies. According to International Conference on Harmonization E14 documents, such
Circ Cardiovasc Interv. 2026 Oct 15:e016552. doi: 10.1161/CIRCINTERVENTIONS.126.016552. Online ahead of print.ABSTRACTBACKGROUND: Myocardial infarction with nonobstructive coronary arteries (MINOCAs) and angina with nonobstructive coronary arteries (ANOCAs) present diagnostic and therapeutic challen
Clin Physiol Funct Imaging. 2026 Nov;46(6):e70099. doi: 10.1111/cpf.70099.ABSTRACTOBJECTIVE: Surgical mitral valve repair, including anchoring in different parts of the mitral apparatus, is the standard of care for severe mitral regurgitation. Various percutaneous approaches have been developed and
Taiwan J Ophthalmol. 2025 Jul 15;16(3):435-441. doi: 10.4103/tjo.TJO-D-25-00055. eCollection 2026 Jul-Sep.ABSTRACTPURPOSE: The aim of our study was to analyze the association between different cardiovascular risk scores and swept-source optical coherence tomography angiography (SS-OCTA) quantitative
J Innov Card Rhythm Manag. 2026 Sep 15;17(9):6850-6853. doi: 10.19102/icrm.2026.17096. eCollection 2026 Sep.ABSTRACTPulsed field ablation (PFA) using the Farapulse™ system (Boston Scientific, Marlborough, MA, USA) is a novel, non-thermal ablation technology developed to treat atrial fibrillation (AF
J Innov Card Rhythm Manag. 2026 Sep 15;17(9):6854-6856. doi: 10.19102/icrm.2026.17093. eCollection 2026 Sep.ABSTRACTWe report a case of transient ischemic attack due to a thromboembolic event secondary to delamination of the steerable guiding sheath, CARTO VIZIGO™ (J&J MedTech, New Brunswick, NJ, US
IEEE J Transl Eng Health Med. 2026 Sep 3;14:380-389. doi: 10.1109/JTEHM.2026.3730465. eCollection 2026.ABSTRACTOBJECTIVE: To determine whether a two-lead ECG (wECG), acquired using a self-applicable, wrist-worn device, provides diagnostic value in acute myocardial infarction (AMI) detection.METHODS:
Eur J Case Rep Intern Med. 2026 Sep 25;13(10):007397. doi: 10.12890/2026_007397. eCollection 2026.ABSTRACTINTRODUCTION: Hirayama disease (HD) is a rare, self-limiting cervical flexion myelopathy causing progressive, painless distal upper-limb weakness, typically in young Asian males. Loeys-Dietz syn
Pulm Circ. 2026 Oct 14;16(4):e70413. doi: 10.1002/pul2.70413. eCollection 2026 Oct.ABSTRACTPulmonary hypertension (PH) is a fatal sequela in sickle cell disease (SCD) patients and occurs with greater prevalence compared to the general population. Macrophages (Mϕ) are one of the first immune cells to
IEEE Open J Eng Med Biol. 2026 Aug 11;7:324-331. doi: 10.1109/OJEMB.2026.3722470. eCollection 2026.ABSTRACTCardiovascular diseases are the leading cause of global mortality, with millions of patients relying on implantable pacemakers. Finite battery energy fundamentally limits remote monitoring. Usi
Eur Heart J Open. 2026 Aug 14;6(5):oeag123. doi: 10.1093/ehjopen/oeag123. eCollection 2026 Sep.ABSTRACTAIMS: Accumulating evidence indicates that anti-Ro/Sjögren's syndrome-related antigen A (SSA) antibodies, specifically the anti-Ro/SSA-52kD subtype, can promote heart rate-corrected QT interval (QT
Front Psychiatry. 2026 Sep 30;17:1883542. doi: 10.3389/fpsyt.2026.1883542. eCollection 2026.ABSTRACTOBJECTIVES: To characterize longitudinal trajectories of psychological distress from first presentation to a weight management clinic through 6 months of weight loss.METHODS: Adults with obesity (body
Arch Med Sci. 2026 Aug 20;22(4):1933-1947. doi: 10.5114/aoms/221929. eCollection 2026.ABSTRACTINTRODUCTION: Cardiovascular disease (CVD) is a major public health concern, and its burden and trends require further clarification. This study aimed to compare the CVD burden between China and the global
Eur Heart J Open. 2026 Sep 26;6(5):oeag144. doi: 10.1093/ehjopen/oeag144. eCollection 2026 Sep.ABSTRACTAIMS: Transition from paediatric to adult congenital heart disease (ACHD) care is a critical determinant of lifelong disease management for individuals with congenital heart disease (CHD). However,
BMJ Public Health. 2026 Oct 14;4(4):e005169. doi: 10.1136/bmjph-2026-005169. eCollection 2026.ABSTRACTINTRODUCTION: Replacing regular salt with potassium-enriched salt has been identified as a promising strategy to reduce blood pressure and prevent cardiovascular diseases. However, its implementatio
Front Immunol. 2026 Sep 30;17:1957976. doi: 10.3389/fimmu.2026.1957976. eCollection 2026.ABSTRACTDiabetic foot ulcer healing is compromised because metabolic, inflammatory and tissue-repair processes fail to proceed in a coordinated and timely manner. Persistent hyperglycemia, metabolic stress and o
