Spatiotemporal orchestration of macrophage heterogeneity by cell adhesion molecules

Acta Biochim Biophys Sin (Shanghai). 2026 Jul 16;58(8):1703-1718. doi: 10.3724/abbs.2026127.ABSTRACTMonocyte-derived macrophages (mo-macs) are central regulators of innate immunity and are essential for maintaining physiological homeostasis and host defense. Their functional efficacy relies on preci

J Jing Yu

Integrative transcriptomic and single-cell analysis identifies anoikis-related molecular signatures in vascular calcification

Ren Fail. 2026 Dec;48(1):2704989. doi: 10.1080/0886022X.2026.2704989. Epub 2026 Aug 24.ABSTRACTBACKGROUND: Vascular calcification (VC) is a life-threatening complication of chronic kidney disease (CKD) driven by vascular smooth muscle cell (VSMC) osteogenic transdifferentiation. Anoikis, a form of a

D Dandan Chen

Perimenopause and metabolic vulnerability: hormones, body composition and lifestyle changes

Climacteric. 2026 Aug 24:1-16. doi: 10.1080/13697137.2026.2713394. Online ahead of print.ABSTRACTPerimenopause is a transitional phase characterized by substantial hormonal fluctuations, particularly declining estradiol levels, accompanied by age-related metabolic changes. Increasing evidence sugges

V Vanessa Alves Lobato

Effects and mechanism of pterostilbene on angiotensin II-induced myocardial hypertrophy and fibrosis

Acta Biochim Biophys Sin (Shanghai). 2026 Jan 25. doi: 10.3724/abbs.2026096. Online ahead of print.ABSTRACTPressure overload-induced cardiac hypertrophy and myocardial fibrosis constitute key pathological substrates of heart failure and arrhythmias. This study investigates the protective effects of

J Jiwei Gu

Herpes zoster and respiratory syncytial virus vaccination in patients with cardiovascular-kidney-metabolic syndrome in Hong Kong

No abstractHong Kong Med J. 2026 Aug;32(4):291-296. doi: 10.12809/hkmj265196.NO ABSTRACTPMID:42634858 | DOI:10.12809/hkmj265196

W W Lam

Red Cell Distribution Width Predicts Mortality in Critically Ill Patients with COPD and Atrial Fibrillation: A Retrospective Cohort Study

Int J Chron Obstruct Pulmon Dis. 2026 Aug 19;21:611640. doi: 10.2147/COPD.S611640. eCollection 2026.ABSTRACTBACKGROUND: Critically ill patients with COPD and atrial fibrillation (AF) face a substantially poor prognosis. Given the established prognostic value of red cell distribution width (RDW) in e

B Bo Xie

Intuitive and Deliberative Dietary Decision-Making Preferences and Associated Factors in Cardiovascular Patients: A Cross-Sectional Study

Patient Prefer Adherence. 2026 Aug 19;20:627640. doi: 10.2147/PPA.S627640. eCollection 2026.ABSTRACTOBJECTIVE: This study investigated the current status of dietary decision-making preferences and associated factors in patients with cardiovascular disease, aiming to provide preliminary evidence for

M Meiyun Yang

Transcriptomic landscape of human circular RNAs: unveiling molecular mechanisms in high-altitude adaptation

Front Genet. 2026 Aug 10;17:1823611. doi: 10.3389/fgene.2026.1823611. eCollection 2026.ABSTRACTHigh altitude (HA) is associated with environmental stress and low oxygen levels, and HA adaptation varies among populations. This study aimed to explore HA adaptation-related circular RNAs (circRNAs) and

B Buhe Bao

Association Between Type of Antidiabetic Treatment and Glycemic Control in Patients With Type 2 Diabetes Mellitus: A Retrospective Cross-Sectional Study

Cureus. 2026 Jul 23;18(7):e113266. doi: 10.7759/cureus.113266. eCollection 2026 Jul.ABSTRACTBACKGROUND: Maintaining adequate glycemic control remains a major challenge in patients with type 2 diabetes mellitus (T2DM). Patients requiring insulin therapy often have longer disease duration and more adv

R Rafael Violante-Ortiz

Association of Iron Deficiency With the Severity of Heart Failure With Preserved Ejection Fraction: A Hospital-Based Comparative Observational Study From Bangladesh

Cureus. 2026 Jul 24;18(7):e113308. doi: 10.7759/cureus.113308. eCollection 2026 Jul.ABSTRACTBackground Iron deficiency is a prevalent and clinically significant comorbidity in heart failure with preserved ejection fraction (HFpEF), yet local data from Bangladesh remain scarce. This study aimed to ex

D Dewan Mushfiq Raihan

Arylsulfonylaminopyridines as Potential Epac Inhibitors: Design, Synthesis and Effects on Myocardial Strips

Med Chem. 2026 Aug 5. doi: 10.2174/0115734064504072260724092027. Online ahead of print.ABSTRACTINTRODUCTION: Exchange proteins directly activated by cyclic AMP (Epac) represent a promising therapeutic target for developing novel cardiotropic agents. Epac-dependent signaling regulates intracellular c

T Tatiana Vorobeva

Therapeutic Potential of Herbal Saponin Constituents in Myocardial Ischemia/Reperfusion Injury: A Review and Network Pharmacological Analysis

Mini Rev Med Chem. 2026 Aug 3. doi: 10.2174/0113895575442404260724031217. Online ahead of print.ABSTRACTINTRODUCTION: Myocardial Ischemia (MI) is one of the leading causes of death from cardiovascular disease. While reperfusion restores blood supply to ischemic areas, the primary treatment for MI, i

Y Yulei Wang

From Peptides to Aliskiren: The Evolution of Direct Renin Inhibitors in Hypertension Therapy

Mini Rev Med Chem. 2026 Aug 3. doi: 10.2174/0113895575447246260730050136. Online ahead of print.ABSTRACTHypertension remains a major global health concern, significantly contributing to the burden of cardiovascular, renal, and cerebrovascular diseases. Conventional pharmacological interventions incl

P Pubali Saha

Psychiatric Issues in Cardiovascular Disease, Chronic Kidney Disease, Lung Cancer, and Neurological Disorders

No abstractInt J Psychiatry Med. 2026 Aug 23:912174261480941. doi: 10.1177/00912174261480941. Online ahead of print.NO ABSTRACTPMID:42634448 | DOI:10.1177/00912174261480941

Relationship Between Estimated Pulse Wave Velocity and Mortality Risk in Patients with Atrial Fibrillation: A Retrospective Cohort Analysis of Medical Information Mart for Intensive Care-IV Database

Anatol J Cardiol. 2026 Aug 24. doi: 10.14744/AnatolJCardiol.2026.6392. Online ahead of print.ABSTRACTOBJECTIVE: Pulse wave velocity (PWV) serves as a reliable indicator of arterial stiffness and is correlated with the occurrence and prognosis of cardiovascular diseases. This analysis investigates th

N Nan Xia

A Retrospective Analysis of 581 Cases of Esophagogastric Variceal Bleeding Complicated by Portal Vein Thrombosis at a Single Center

Can J Gastroenterol Hepatol. 2026;2026(1):e8185878. doi: 10.1155/cjgh/8185878.ABSTRACTBACKGROUND: Esophagogastric variceal bleeding (EGVB) and portal vein thrombosis (PVT) are common complications of liver cirrhosis and frequently coexist, with reported prevalence rate up to 32.5%. Their coexistence

J Jiayi Zhang

Pharmacokinetic/Pharmacodynamic Translation and Model-Informed Drug Development for Oligonucleotide Therapeutics

J Clin Pharmacol. 2026 Aug;66(8):e70267. doi: 10.1002/jcph.70267.ABSTRACTSmall interfering RNAs (siRNAs) and antisense oligonucleotides (ASOs) have emerged as clinically validated therapeutic modalities, with approvals and late-stage development programs spanning rare genetic, neurologic, cardiovasc

P Paridhi Gupta

Prenatal Evaluation of Genetic Abnormalities in Fetuses With Single Umbilical Artery: A Retrospective Cohort Study

Genet Res (Camb). 2026;2026(1):e3827416. doi: 10.1155/genr/3827416.ABSTRACTOBJECTIVE: To investigate the genetic factors associated with fetal single umbilical artery (SUA) and concomitant structural anomalies.METHODS: A retrospective review was performed on the ultrasound characteristics of 375 SUA

Y Yuqin Chen

A systematic review to critically appraise methodological rigor in research on ultra-processed food and cardiovascular disease and hypertension

Crit Rev Food Sci Nutr. 2026 Aug 23:1-23. doi: 10.1080/10408398.2026.2719168. Online ahead of print.ABSTRACTDespite growing research linking ultra-processed food (UPF) consumption to risk of cardiovascular disease (CVD) and hypertension, no study has systematically evaluated the methodological rigor

T Tefera Chane Mekonnen

Recent Advances in Endogenous Gas-Responsive Drug Delivery Systems

Recent Adv Drug Deliv Formul. 2026 Aug 10. doi: 10.2174/0126673878465553260730051347. Online ahead of print.ABSTRACTRecent advances in Drug Delivery Systems (DDS) have focused on minimizing systemic side effects while enhancing therapeutic precision. Endogenous gas-responsive DDS represent a promisi

M Minal Narkhede

Interpreting Triglycerides: A National Cross-Sectional Review of Laboratory Reporting Practices

No abstractDiabetes Obes Metab. 2026 Aug 23. doi: 10.1111/dom.71254. Online ahead of print.NO ABSTRACTPMID:42634325 | DOI:10.1111/dom.71254

J Jeff R Ma

Carvedilol Beyond the Heart: Pleiotropic Mechanisms and Emerging Therapeutic Applications Across Organ Systems

Curr Pharm Des. 2026 Aug 6. doi: 10.2174/0113816128489643260728112117. Online ahead of print.ABSTRACTCarvedilol (CVR) is a nonselective β1- and β2-adrenergic receptor antagonist with additional α1-adrenergic blocking activity, commonly used to treat heart failure, hypertension, and left ventricular

D Dhirendra Singh

Huatuo Zaizao Pills Alleviate Neuroinflammation and Neuronal Apoptosis via Microglial M2 Polarization in a Permanent Cerebral Ischemia Mouse Model

Curr Pharm Des. 2026 Aug 6. doi: 10.2174/0113816128472276260724223326. Online ahead of print.ABSTRACTINTRODUCTION: This study aimed to explore the potential neuroprotective effects of Huatuo Zaizao pills (HTZZ) in modulating microglial polarization-mediated neuroinflammation and apoptosis.MATERIALS

D Die Deng

Venous Congestion in Metabolic Heart Disease: Potential Indirect Role of Dual Incretin Agonists

Cardiovasc Hematol Disord Drug Targets. 2026 Aug 6. doi: 10.2174/011871529X502187260803101832. Online ahead of print.ABSTRACTINTRODUCTION: Venous congestion is responsible for symptoms, organ dysfunction, and negative outcomes in heart failure. In obesity-related Heart Failure (HF) with preserved ej

S Sidhartha Gautam Senapati