Construction and validation of a risk predictive model for fear of disease progression in patients after percutaneous coronary intervention

Sci Rep. 2025 Dec 6. doi: 10.1038/s41598-025-31099-7. Online ahead of print.ABSTRACTThis study aimed to construct and validate a predictive model for fear of disease progression in patients after percutaneous coronary intervention(PCI). From March to October 2024, 455 post-PCI patients in the Depart

Y Yuxin Li

Fatty acid-binding protein 5 aggravates psoriasis and psoriasis-like disease through ferroptosis

Cell Death Differ. 2025 Dec 6. doi: 10.1038/s41418-025-01630-4. Online ahead of print.ABSTRACTPsoriasis (Ps) is a chronic inflammatory skin disease with systemic manifestations, such as psoriatic arthritis (PsA), cardiovascular and psychiatric complications, and subsequent negative effects on patien

K Kamil Mieczkowski

Association between changes in Chinese visceral adiposity index and cardiovascular disease among middle-aged and older Chinese adults

Sci Rep. 2025 Dec 6. doi: 10.1038/s41598-025-31561-6. Online ahead of print.ABSTRACTPrevious studies have established visceral adiposity as a risk factor for cardiovascular disease (CVD), but the relationship between longitudinal changes in Chinese Visceral Adiposity Index (CVAI) and CVD risk has no

L Li-Hua Huang

The association between tooth loss and serum cholesterol levels in adults: a scoping review

BMC Oral Health. 2025 Dec 6. doi: 10.1186/s12903-025-07431-y. Online ahead of print.ABSTRACTOBJECTIVE: This scoping review systematically mapped the evidence on the association between tooth loss and serum cholesterol levels in adults, addressing a significant gap in understanding the direct link be

K Keyi Wan

Cyclophilin B deficiency enhances myocardial energy synthesis and protects against heart failure in preclinical models

BMC Med. 2025 Dec 7. doi: 10.1186/s12916-025-04563-4. Online ahead of print.ABSTRACTBACKGROUND: Heart failure (HF) represents the end stage of cardiovascular diseases with high mortality and limited treatment options. Cyclophilin B (CypB), known mainly as an endoplasmic reticulum chaperone, has been

X Xiao Zong

Survival impact of anti-CD38-based quadruplet regimens in transplant-ineligible newly diagnosed multiple myeloma: a network meta-analysis and reconstructed individual patient data meta-analysis

Blood Cancer J. 2025 Dec 6;15(1):212. doi: 10.1038/s41408-025-01413-7.ABSTRACTFrontline therapy for transplant-ineligible newly diagnosed multiple myeloma (TI-NDMM) has advanced with anti-CD38 monoclonal antibody (mAb)-based regimens. Although quadruplet combinations incorporating daratumumab and is

J João Tadeu Damian Souto Filho

Protective effects of biomimetic Cu-Zn-MOF against DOX-Induced cardiotoxicity through inhibiting oxidative stress and ferroptosis

J Nanobiotechnology. 2025 Dec 6. doi: 10.1186/s12951-025-03902-0. Online ahead of print.ABSTRACTBACKGROUND: Doxorubicin (DOX), a member of the anthracycline family, is widely recognized as an effective chemotherapeutic agent for cancer treatment. However, its clinical application is limited due to i

J Jian Wang

Androgen deprivation therapy with apalutamide in the treatment of metastatic castration-sensitive prostate cancer: the systematic review of its effectiveness and applicability for Asian men in the targeted investigational treatment analysis of novel anti-androgen (TITAN) trial

Int Urol Nephrol. 2025 Dec 6. doi: 10.1007/s11255-025-04943-y. Online ahead of print.ABSTRACTBACKGROUND: The TITAN trial established survival benefits of adding apalutamide to androgen deprivation therapy (ADT) in metastatic castration‑sensitive prostate cancer (mCSPC). Whether efficacy and safety a

F Fan Yang

Time-updated FIB-4 index predicts coronary artery calcification progression in individuals with metabolic dysfunction-associated steatotic liver disease

Sci Rep. 2025 Dec 6. doi: 10.1038/s41598-025-31289-3. Online ahead of print.ABSTRACTMetabolic dysfunction-associated steatotic liver disease (MASLD) is the most common chronic liver disorder worldwide and is increasingly recognized as a multisystem disease that elevates cardiovascular disease (CVD)

Y Yesung Lee

Impact of bariatric surgery on metabolic-dysfunction associated fatty liver disease in diabetic and non-diabetic patients: a cohort study

No abstractBMC Gastroenterol. 2025 Dec 7. doi: 10.1186/s12876-025-04524-4. Online ahead of print.NO ABSTRACTPMID:41353247 | DOI:10.1186/s12876-025-04524-4

M Mohammad Sistanizad

Real-world study to compare functional SYNTAX score versus anatomical SYNTAX score in influencing the treatment strategy for multivessel disease patients

Sci Rep. 2025 Dec 6. doi: 10.1038/s41598-025-30804-w. Online ahead of print.ABSTRACTThere are limited prospective clinical studies that use the functional SYNTAX score (FSS) to determine treatment strategies, as compared to the anatomical SYNTAX score (ASS), in patients with multivessel disease (MVD

N Nattawut Wongpraparut

Proteome-wide association study of prostate cancer risk across populations

Nat Commun. 2025 Dec 6. doi: 10.1038/s41467-025-66250-5. Online ahead of print.ABSTRACTThere is insufficient understanding of the molecular basis of prostate cancer (PCa) across different populations. We perform a large-scale proteome-wide association study (PWAS) to identify proteins with genetical

H Hua Zhong

Autophagy and mitophagy in dermatological disease: a comprehensive review from molecular pathways to therapeutic frontiers

Biol Direct. 2025 Dec 6. doi: 10.1186/s13062-025-00703-1. Online ahead of print.ABSTRACTAutophagy - the cell's built-in recycling and quality-control programme - touches every layer of cutaneous biology. In keratinocytes it sculpts the cornified envelope; in melanocytes it balances pigment synthesis

L Luca D'Ambrosio

Independent and combined effects of mean blood glucose and glycemic variability on 28-day mortality in older acute myocardial infarction patients: a MIMIC-IV cohort study

No abstractBMC Geriatr. 2025 Dec 6. doi: 10.1186/s12877-025-06499-z. Online ahead of print.NO ABSTRACTPMID:41353156 | DOI:10.1186/s12877-025-06499-z

J Jun Zhou

The rs34416841 polymorphism in the Alu element of the circSirt1 flanking intron is associated with an increased risk of myocardial infarction

BMC Med Genomics. 2025 Dec 6. doi: 10.1186/s12920-025-02291-5. Online ahead of print.ABSTRACTBACKGROUND: circSirt1 can ameliorate neointimal hyperplasia and provide protection against atherosclerosis. Single nucleotide polymorphisms (SNPs) in circRNA flanking introns, particularly within Alu element

Y Yu-Lan Zhou

Succinate-GPR91 signaling promotes cardiomyocyte metabolic reprogramming and NAD+ production to alleviate HFpEF

Cardiovasc Diabetol. 2025 Dec 6. doi: 10.1186/s12933-025-03030-x. Online ahead of print.ABSTRACTBACKGROUND: Disrupted cardiomyocyte energy metabolism is a hallmark of heart failure with preserved ejection fraction (HFpEF). Succinate, a key intermediate of the tricarboxylic acid cycle, is markedly de

Y Yumeng Jia

Weight-adjusted waist index outperforms other obesity indices for cardiovascular disease prediction in cardiovascular-kidney-metabolic syndrome: insights from UK biobank

BMC Public Health. 2025 Dec 7. doi: 10.1186/s12889-025-25830-2. Online ahead of print.ABSTRACTBACKGROUND: Cardiovascular-kidney-metabolic (CKM) syndrome, a systemic disorder often initiated by adipose tissue dysfunction, is an emerging concept for integrated risk assessment. Although the link betwee

T Tianyu Wang

Estimated glucose disposal rate and mortality risk in cardiovascular-kidney-metabolic syndrome: a population-based study

BMC Endocr Disord. 2025 Dec 6. doi: 10.1186/s12902-025-02119-4. Online ahead of print.ABSTRACTBACKGROUND: Cardiovascular-kidney-metabolic (CKM) syndrome is a systemic disorder characterized by the interrelated dysfunction of metabolic abnormalities, chronic kidney disease, and cardiovascular injury,

Z Zheng Zhang

Attainment of Low-Density Lipoprotein Cholesterol Goals and Statin Use in Patients With Atherosclerotic Cardiovascular Disease in Australian General Practice: Are We Doing Enough?

Heart Lung Circ. 2025 Dec 5:S1443-9506(25)01560-4. doi: 10.1016/j.hlc.2025.07.012. Online ahead of print.ABSTRACTAIM: We sought to investigate the use of lipid-lowering therapy (LLT) and the attainment of low-density lipoprotein cholesterol (LDL-C) goals in patients with atherosclerotic cardiovascul

R Ralph G Audehm

Emerging trends and hotspots of the link between gut probiotics and obesity from 2000 to 2024: A bibliometric analysis

Obes Res Clin Pract. 2025 Dec 5:S1871-403X(25)00137-1. doi: 10.1016/j.orcp.2025.12.001. Online ahead of print.ABSTRACTBACKGROUND: In recent decades, the global prevalence of obesity has surged, intricately linked to hypertension, stroke, type 2 diabetes, cardiovascular diseases, and cancer. However,

X Xiwei Li

The changing landscape of heart failure: translating management into the modern era

Eur J Intern Med. 2025 Dec 5:106633. doi: 10.1016/j.ejim.2025.106633. Online ahead of print.ABSTRACTHeart failure (HF) is a complex clinical syndrome associated with high morbidity and mortality, accounting for approximately 2 % of total healthcare expenditures. Despite advances in pharmacological a

C Cristina Madaudo

Mental health and cardiovascular disease: A significant reciprocal impact

No abstractArch Cardiovasc Dis. 2025 Dec 2:S1875-2136(25)00828-9. doi: 10.1016/j.acvd.2025.11.007. Online ahead of print.NO ABSTRACTPMID:41353020 | DOI:10.1016/j.acvd.2025.11.007

J Jean-Jacques Monsuez

The increase of monocyte/high-density lipoprotein cholesterol ratio precedes recurrent thrombosis in patients with antiphospholipid syndrome

Rheumatology (Oxford). 2025 Dec 6:keaf655. doi: 10.1093/rheumatology/keaf655. Online ahead of print.ABSTRACTOBJECTIVES: The monocyte-to-high-density lipoprotein cholesterol ratio (MHR) is an emerging biomarker associated with inflammation and oxidative stress, being linked to cardiovascular events i

H Haruka Moriya

Dual-organoid biosensor for monitoring cardiac conduction disturbances in vitro

Anal Chim Acta. 2026 Jan 15;1383:344874. doi: 10.1016/j.aca.2025.344874. Epub 2025 Nov 9.ABSTRACTAccurate detection of conduction disorders, a critical factor for arrhythmogenic risk assessment, is a key challenge in drug development and cardiovascular safety screening. This study presents a highly

F Filip Svěrák