Incidence of Hypotension in Patients Undergoing Subarachnoid Block in Sitting versus Lateral Decubitus Position in Elective Lower Limb Surgeries

Kathmandu Univ Med J (KUMJ). 2025 Oct-Dec;23(92):529-533.ABSTRACTBackground Subarachnoid block (SAB) is a widely practiced regional anesthetic for lower limb surgeries. The patient position for subarachnoid block induction, either sitting or lateral decubitus, may affect hemodynamic stability and bl

B B Paudel

Challenging pacemaker implantation in a child with aggressive atrial standstill caused by compound heterozygous SCN5A variants

Cardiol Young. 2026 Jun 19:1-8. doi: 10.1017/S1047951126113511. Online ahead of print.ABSTRACTINTRODUCTION: Atrial standstill represents a rare cardiac arrhythmia characterised by the complete absence of atrial electrical and mechanical activity. Early diagnostic recognition coupled with comprehensi

Y Yu Qiu

Interfacial Regulation-Driven Dual-Enrichment SERS Coupled With Deep Learning Enable Ultrasensitive and In Situ Identification of Microplastics in Natural Waters

Small. 2026 Jun 19:e74231. doi: 10.1002/smll.74231. Online ahead of print.ABSTRACTAccurate detection of trace-level microplastics in natural waters remains challenging due to inefficient particle enrichment, unstable particle-substrate interactions, inhomogeneous hotspot distributions, and spectral

C Chaochao Ma

Wearable-Derived Diurnal Alignment Between Physical Activity and Device Temperature Predicts Future Disease and Mortality Risk

Adv Sci (Weinh). 2026 Jun 19:e76217. doi: 10.1002/advs.76217. Online ahead of print.ABSTRACTCircadian rhythms coordinate physiology with the 24 h light-dark cycle, and their disruption contributes to diseases spanning metabolic, cardiovascular, and neuropsychiatric domains. Whether the temporal cohe

H Han Chen

Mitochondrial Dysfunction Unravels the Potential Molecular Link Between Night Shift Work-Related Circadian Disruption and Elevated Blood Pressure in Human and Mouse Models

Adv Sci (Weinh). 2026 Jun 19:e20318. doi: 10.1002/advs.202520318. Online ahead of print.ABSTRACTThis study demonstrates that circadian rhythm disruption induced by night-shift work is associated with elevated blood pressure in both murine models and human subjects. By integrating rodent and human ep

Z Zhaoqiang Jiang

Phenotypic Characterization of Unclassified Pulmonary Hypertension

Circ Heart Fail. 2026 Jun 19:e014480. doi: 10.1161/CIRCHEARTFAILURE.125.014480. Online ahead of print.ABSTRACTBACKGROUND: Some symptomatic patients manifest pulmonary hypertension (PH), despite normal pulmonary vascular resistance and pulmonary artery wedge pressure-a condition termed unclassified P

Y Yogesh N V Reddy

Glycine Receptor α2 Mediates Vasodilation via Endothelial eNOS Signaling

Circ Res. 2026 Jun 19. doi: 10.1161/CIRCRESAHA.126.328205. Online ahead of print.ABSTRACTBACKGROUND: Endothelium-derived NO is an important vasodilator essential for maintaining vascular homeostasis. However, how eNOS (endothelial nitric oxide synthase) is regulated in hypertension conditions is not

X Xueya Bai

GLP-1 Agonists in Adolescent Obesity: A Narrative Review of Single, Dual, and Triple Agonists

Diabetes Metab Syndr Obes. 2026 Jun 12;19:566414. doi: 10.2147/DMSO.S566414. eCollection 2026.ABSTRACTAdolescent obesity is an escalating global health concern associated with increased risks of cardiovascular disease, type 2 diabetes mellitus, and long-term metabolic complications. Although lifesty

M Mahroz Abid

Mineral encapsulation of microorganisms in calcified oral biofilms: implications for immune dysregulation and vascular calcification

Front Dent Med. 2026 Jun 3;7:1849108. doi: 10.3389/fdmed.2026.1849108. eCollection 2026.ABSTRACTOral biofilms represent highly organized microbial ecosystems embedded within extracellular matrices enriched with calcium and phosphate ions that promote the nucleation of calcium phosphate minerals, inc

J Jayalaxmi Shetty

Modelled CKD Benefits of Broad Sodium-Glucose Cotransporter-2 Inhibitor Eligibility in the UK

Kidney Int Rep. 2026 May 15;11(8):106602. doi: 10.1016/j.ekir.2026.106602. eCollection 2026 Aug.ABSTRACTINTRODUCTION: Chronic kidney disease (CKD) affects >10% of the UK population and is expected to increase. Sodium-glucose cotransporter-2 inhibitors (SGLT-2is) are effective at slowing CKD progress

N Navdeep Tangri

Efficacy and Safety of Bloodletting Therapy in Patients with Knee Osteoarthritis: A Meta-Analysis

J Pain Res. 2026 Jun 12;19:600101. doi: 10.2147/JPR.S600101. eCollection 2026.ABSTRACTINTRODUCTION: Knee osteoarthritis (KOA) is a prevalent degenerative joint disease that severely undermines the quality of life in middle-aged and elderly people. Pain is the predominant clinical symptom of KOA. Exi

S Shuai Dong

A chamber study of respiratory and autonomic responses to hydrotreated vegetable oil exhaust using ECG-derived respiration

Front Physiol. 2026 Jun 3;17:1710755. doi: 10.3389/fphys.2026.1710755. eCollection 2026.ABSTRACTBACKGROUND: Air pollution is a major public health concern, contributing to cardiovascular and respiratory diseases. One of the main pathways by which air pollution affects cardiovascular health is throug

M Mostafa Abdollahpur

Systematic review of cardiovascular care delivery across health systems in the Asia-Pacific: a regional roadmap for strengthening cardiovascular care

Lancet Reg Health West Pac. 2026 Jun 10;71:101902. doi: 10.1016/j.lanwpc.2026.101902. eCollection 2026 Jun.ABSTRACTBACKGROUND: Achieving universal health coverage in the Asia-Pacific requires stronger, more equitable access to high-quality cardiovascular disease (CVD) services. Yet, despite the regi

N Nicholas Ws Chew

Programs to Partnerships: A Brief Report on the Texas A&M AgriLife Extension Service HealthTalk Express Program

J Healthy Eat Act Living. 2026 May 1;6(1):76-82. eCollection 2026.ABSTRACTChronic diseases remain a pressing issue in Texas, where high rates of obesity, diabetes, and cardiovascular conditions challenge public health. The Texas A&M AgriLife Extension Service addresses health by translating research

D Debra K Kellstedt

Venous thromboembolic and bleeding risk in population with obesity hospitalized for an acute medical illness receiving enoxaparin for thromboprophylaxis

Res Pract Thromb Haemost. 2026 Apr 30;10(4):106628. doi: 10.1016/j.rpth.2026.106628. eCollection 2026 May.ABSTRACTBACKGROUND: Patients with obesity hospitalized for acute medical illness are at increased venous thromboembolism (VTE) risk, but evidence on predictors of VTE and major bleeding (MB) to

W Walter Ageno

Identifying risk factors for venous thromboembolism in medical inpatients: a systematic review and meta-analysis

Res Pract Thromb Haemost. 2026 Apr 30;10(4):106625. doi: 10.1016/j.rpth.2026.106625. eCollection 2026 May.ABSTRACTBACKGROUND: Hospitalized medical patients are at increased risk of venous thromboembolism (VTE). Current VTE-risk assessment models do not adequately identify which patients would benefi

R Rachel E Clapham

A plasma N-acetyl amino acid panel for type 2 diabetes discrimination built by targeted LC-MS/MS: A case-control study

Front Med (Lausanne). 2026 Jun 3;13:1830709. doi: 10.3389/fmed.2026.1830709. eCollection 2026.ABSTRACTBACKGROUND: Type 2 diabetes (T2D) is characterized by profound metabolic disturbances, yet clinically actionable biomarkers beyond conventional glycaemic indices remain limited. N-acetyl amino acids

S Shusi Ding

Factor XI inhibition with gruticibart prevents mechanical valve thrombosis in a porcine pulmonary model

Blood Vessel Thromb Hemost. 2026 Apr 13;3(3):100168. doi: 10.1016/j.bvth.2026.100168. eCollection 2026 Aug.ABSTRACTMechanical heart valves have excellent lifelong durability but require lifelong anticoagulation, traditionally with vitamin K antagonists, which increase bleeding risk and require monit

T Tom Langenaeken

Supranormal Ejection Fraction as a Clinical Red Flag: Differentiating Hemodynamic Stress From Intrinsic Cardiomyopathy in Heart Failure

Mayo Clin Proc Innov Qual Outcomes. 2026 Jun 10;10(4):100726. doi: 10.1016/j.mayocpiqo.2026.100726. eCollection 2026 Aug.ABSTRACTOBJECTIVE: To show that heart failure with supranormal ejection fraction (HFsnEF, left ventricular ejection fraction [LVEF] ≥ 65%) is not a marker of cardiac health but a

Y Yanjia Chen

Adolescent physical activity trajectories and later non-communicable disease risk factors: A systematic review of longitudinal studies

Public Health Pract (Oxf). 2026 May 20;12:100811. doi: 10.1016/j.puhip.2026.100811. eCollection 2026 Dec.ABSTRACTOBJECTIVES: To systematically examine the associations between adolescent physical activity (PA) trajectories and the development of non-communicable disease (NCD) risk factors, and to id

P Poovitha Shruthi Paramashiva

Empagliflozin-pirfenidone dual therapy improves cardiac function and structure in a preclinical two-hit HFpEF model

Front Pharmacol. 2026 Jun 3;17:1781866. doi: 10.3389/fphar.2026.1781866. eCollection 2026.ABSTRACTBACKGROUND: Heart failure with preserved ejection fraction (HFpEF) accounts for more than half of heart failure cases and is associated with substantial morbidity and mortality. Although sodium-glucose

Y Yuexin Yu

The current status and influencing factors of medication literacy among patients with cardiovascular diseases: a systematic review and meta-analysis

Front Pharmacol. 2026 Jun 3;17:1849302. doi: 10.3389/fphar.2026.1849302. eCollection 2026.ABSTRACTBACKGROUND: As an important domain of health literacy, medication literacy plays a critical role in ensuring the safe and effective use of medicines, especially among individuals with Cardiovascular Dis

T Ting Xu

Ondansetron derivatives as potential PTP1B inhibitors for treating type 2 diabetes mellitus: in silico, in vitro, and in vivo analysis

Front Pharmacol. 2026 Jun 3;17:1796359. doi: 10.3389/fphar.2026.1796359. eCollection 2026.ABSTRACTINTRODUCTION: Type 2 diabetes has become one of the most common causes of human deaths. Key factors that contribute to the progression of this disease include a sedentary lifestyle, high-fat diet, and g

F Fawad Naeem

UPLC-MS/MS profiling, antioxidant and hemorheological effects of D101 resin-based purified flavonoids from Allium polyrhizum

Front Pharmacol. 2026 Jun 3;17:1755360. doi: 10.3389/fphar.2026.1755360. eCollection 2026.ABSTRACTINTRODUCTION: Oxidative stress and blood stasis represent critical pathological drivers underlying the progression of cardiovascular and cerebrovascular diseases. Total flavonoids derived from Allium po

C Caiquan Zhao