N-Methyl-D-aspartate receptors: structure, signaling and roles in atherosclerosis

J Transl Med. 2026 Jun 6. doi: 10.1186/s12967-026-08399-1. Online ahead of print.ABSTRACTAtherosclerosis, a chronic inflammatory disease of the arterial wall, is a leading cause of cardiovascular diseases worldwide. The complex pathogenesis of atherosclerosis involves genetic predisposition, environ

J Jing Cai

Implementing a primary-tertiary shared care model for enhancing cascade testing for familial hypercholesterolaemia: an effectiveness-implementation hybrid type III pre-post study

Implement Sci Commun. 2026 Jun 6. doi: 10.1186/s43058-026-00988-x. Online ahead of print.ABSTRACTBACKGROUND: Familial hypercholesterolaemia (FH) is a common but underdiagnosed genetic condition that leads to high low-density lipoprotein cholesterol and premature cardiovascular disease. Cascade genet

M Mitchell Sarkies

Association of the CHG Index with the onset, progression, and prognosis of cardiovascular-kidney-metabolic syndrome: findings from two large prospective cohorts

Diabetol Metab Syndr. 2026 Jun 6. doi: 10.1186/s13098-026-02192-2. Online ahead of print.ABSTRACTBACKGROUND: Cardiovascular-kidney-metabolic (CKM) syndrome represents a composite disease state driven by glucose and lipid metabolic dysregulation. The Cholesterol, High-density lipoprotein, and Glucose

Z Zehao Zhao

Identifying high-risk and actionable profiles for prevention in hypertensive patients with concurrent dyslipidemia: a population-based retrospective study

BMC Cardiovasc Disord. 2026 Jun 6. doi: 10.1186/s12872-026-06076-1. Online ahead of print.ABSTRACTBACKGROUND: Hypertension and dyslipidemia are major global risk factors for cardiovascular diseases, with their prevalence increasing annually. In China, hypertension and dyslipidemia exhibit a "dual hi

Y Yizhou Xu

Does the biodiversity of urban green spaces impact on human health? A systematic review of literature

BMC Public Health. 2026 Jun 6. doi: 10.1186/s12889-026-28039-z. Online ahead of print.ABSTRACTGreen spaces and their biodiversity seem to improve the urban life quality. However, a wide range of descriptors were associated with multiple health outcomes, which limits the comparability of existing evi

N Nicola Pelizzari

A Modeling Approach to Inform In Vitro Hypoxia Platforms for Patient-Specific Analyses

Ann Biomed Eng. 2026 Jun 6. doi: 10.1007/s10439-026-04186-7. Online ahead of print.ABSTRACTPURPOSE: Hypoxia is a consequence of diseases such as obstructive sleep apnea (OSA) and can be detrimental to tissue function, with in vitro platforms commonly used to study the associated impacts. However, to

N Nida T Qayyum

Relationship between medication class and ambulatory blood pressure profile in the chronic renal insufficiency cohort (CRIC) study

J Hum Hypertens. 2026 Jun 6. doi: 10.1038/s41371-026-01166-1. Online ahead of print.ABSTRACTPatients with chronic kidney disease (CKD) are at increased risk for masked and nocturnal hypertension, conditions best identified through ambulatory blood pressure (BP) monitoring (ABPM) and associated with

S Sachin V Pasricha

Relating aqueous to vitreous humor proteomics for identification of reliable biomarkers in proliferative diabetic retinopathy

Sci Rep. 2026 Jun 6. doi: 10.1038/s41598-026-55988-7. Online ahead of print.ABSTRACTThis study aimed to identify aqueous humor (AQ) proteins that correlate with vitreous humor (VH) levels in proliferative diabetic retinopathy (PDR). Using paired VH and AQ samples from 41 patients undergoing vitrecto

I Ingeborg Klaassen

Abdominal aortic tortuosity is not associated with other vascular peripheral pathologies or classical cardiovascular risk factors

Sci Rep. 2026 Jun 6. doi: 10.1038/s41598-026-55171-y. Online ahead of print.ABSTRACTAtherosclerosis is a chronic disease which can lead to peripheral vascular occlusion causing cardiovascular, cerebrovascular, and peripheral artery diseases (PAD). Key contributors to PAD include ageing, classical ca

F Francesc Ribas-Aulinas

Cost-effectiveness of genome-guided statin treatment for hypercholesterolemia

Pharmacogenomics J. 2026 Jun 6;26(3):25. doi: 10.1038/s41397-026-00419-z.ABSTRACTCardiovascular disease and hypercholesterolemia present significant global health and economic burdens. While statins are the standard treatment, individual variability and toxicities necessitate personalized approaches

M Margarita-Ioanna Koufaki

Reading Between the Guidelines: Perioperative Implications of the 2025 American Heart Association/American College of Cardiology Hypertension Update

J Cardiothorac Vasc Anesth. 2026 May 13:S1053-0770(26)00383-6. doi: 10.1053/j.jvca.2026.05.008. Online ahead of print.ABSTRACTThe 2025 American Heart Association/American College of Cardiology Guideline for the Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults introd

J Joshua Insler

Impact of hemoglobin glycation index and stress hyperglycemia ratio on short-term mortality in critically ill patients with heart failure: a retrospective cohort study using the MIMIC database

Nutr Metab Cardiovasc Dis. 2026 May 27:104814. doi: 10.1016/j.numecd.2026.104814. Online ahead of print.ABSTRACTBACKGROUND AND AIMS: To evaluate the prognostic value of the combined assessment of hemoglobin glycation index (HGI) and stress hyperglycemia ratio (SHR) for short-term mortality in critic

M Min He

Allergy and Asthma Medication Use in Pregnancy: Safety and Clinical Considerations

J Allergy Clin Immunol Pract. 2026 Jun;14(6):1215-1224. doi: 10.1016/j.jaip.2026.02.038.ABSTRACTAsthma and allergic diseases are highly prevalent among pregnant women, and inadequate control is associated with increased risks of adverse maternal and fetal outcomes. Importantly, concerns about drug s

J Jennifer Namazy

Exploration of 3D fetal cardiac MRI in the late second trimester

J Cardiovasc Magn Reson. 2026 Jun 5:102754. doi: 10.1016/j.jocmr.2026.102754. Online ahead of print.ABSTRACTBACKGROUND: Fetal cardiovascular magnetic resonance imaging (CMR) is restricted to late gestation due to fetal movement and vessel size while initial clinical assessment of the fetal heart is

M Milou Pm van Poppel

Fully Automated Free-Breathing Cardiac MRI at 3T: A Prospective Randomized Study of Image Quality, Efficiency, and Workflow Burden

J Cardiovasc Magn Reson. 2026 Jun 5:102755. doi: 10.1016/j.jocmr.2026.102755. Online ahead of print.ABSTRACTBACKGROUND: Automation in cardiac magnetic resonance (CMR) scans holds the potential to improve examination efficiency and workflow consistency. Prospective clinical evidence validating automa

K Keyi Li

SCORE2 versus HellenicSCORE II+ algorithms in detecting preclinical carotid atherosclerosis in a middle-aged general population sample in Greece

Hellenic J Cardiol. 2026 Jun 5:S1109-9666(26)00114-4. doi: 10.1016/j.hjc.2026.05.006. Online ahead of print.ABSTRACTBACKGROUND AND AIM: Current European guidelines for primary atherosclerotic cardiovascular disease (ASCVD) prevention recommend using Systematic Coronary Risk Evaluation 2 (SCORE2) alg

A Anastasios Kollias

Genomic and proteogenomic insights into Spontaneous Coronary Artery Dissection (SCAD): A systematic review of emerging multi-omic evidence

Vascul Pharmacol. 2026 Jun 5:107657. doi: 10.1016/j.vph.2026.107657. Online ahead of print.ABSTRACTBACKGROUND: Spontaneous coronary artery dissection (SCAD) is a major cause of myocardial infarction in young women without traditional cardiovascular risk factors (Hayes et al., 2018; Adlam et al., 201

A Alice Russo

Cardiac magnetic resonance in patients with acute myocardial infarction: The added clinical value

Vascul Pharmacol. 2026 Jun 5:107656. doi: 10.1016/j.vph.2026.107656. Online ahead of print.ABSTRACTCardiovascular magnetic resonance (CMR) has emerged as the reference noninvasive modality for a comprehensive assessment of myocardial injury following acute myocardial infarction (AMI). Beyond accurat

M Mattia Alberti

Testing community-based strategies to increase hypertension screening in Nigeria: a protocol for an effectiveness-implementation hybrid type III cluster-randomized trial

Contemp Clin Trials. 2026 Jun 5:108367. doi: 10.1016/j.cct.2026.108367. Online ahead of print.ABSTRACTBACKGROUND: Hypertension is a major risk factor for cardiovascular disease and stroke, with a growing burden in Nigeria. Limited access to blood pressure (BP) screenings, low awareness, and barriers

J John Olajide Olawepo

Health burden of transportation noise in the United States: a national assessment with equity analysis

Environ Res. 2026 Jun 5:124921. doi: 10.1016/j.envres.2026.124921. Online ahead of print.ABSTRACTThe United States has not produced a national noise health burden estimate using disability-adjusted life year methodology. We quantified the population health burden of transportation noise across the c

D David Rojas-Rueda

Hypertension-associated gut dysbiosis drives target organ damage through impaired polyunsaturated fatty acids metabolism and immune activation

Pharmacol Res. 2026 Jun 5:108281. doi: 10.1016/j.phrs.2026.108281. Online ahead of print.ABSTRACTHypertension (HTN) is a major risk factor for cardiovascular diseases, with chronic low-grade inflammation emerging as a critical contributor to its development and target organ damage. Emerging evidence

M Minjie Wang

PNPLA3 polymorphisms and risk of hepatic and extrahepatic outcomes in MASLD: a meta-analysis of observational studies

JHEP Rep. 2026 Jun 5:101918. doi: 10.1016/j.jhepr.2026.101918. Online ahead of print.ABSTRACTBACKGROUND & AIMS: The rs738409 C>G polymorphism in the patatin-like phospholipase domain-containing protein 3 gene (PNPLA3 I148M variant) contributes to the largest fraction of metabolic dysfunction-associa

C Ciro Celsa

Medium and Long Term Time to Event Outcomes after Elective Fenestrated and Branched Endovascular Repair of Complex Abdominal and Thoraco-abdominal Aortic Aneurysms: A Systematic Review and Meta-analysis

Eur J Vasc Endovasc Surg. 2026 Jun 5:S1078-5884(26)00524-1. doi: 10.1016/j.ejvs.2026.06.001. Online ahead of print.ABSTRACTOBJECTIVE: To define contemporary medium (3 - 5 years) and long term (>5 years) survival and durability outcomes after elective fenestrated and branched endovascular aortic repa

J Janice Yiu

Valve Oversizing and Geometric Factors in Structural Valve Deterioration After Pulmonary Valve Replacement

Ann Thorac Surg. 2026 Jun 5:S0003-4975(26)00535-7. doi: 10.1016/j.athoracsur.2026.05.036. Online ahead of print.ABSTRACTBACKGROUND: Valve oversizing has been associated with structural valve deterioration after pulmonary valve replacement, but the mechanism is unclear. We investigated whether geomet

Y Yosuke Kugo