Eur J Heart Fail. 2026 Mar 11:xuag071. doi: 10.1093/ejhf/xuag071. Online ahead of print.ABSTRACTBACKGROUND: The effect of β-blockers on heart failure (HF) with preserved ejection fraction (HFpEF) remains controversial. One proposed reason is the confounding influence of common comorbidities such as
Diabetes Metab Res Rev. 2026 Mar;42(3):e70150. doi: 10.1002/dmrr.70150.ABSTRACTAIMS: Gestational Diabetes Mellitus (GDM) is a common metabolic disorder that increases the risk of maternal obesity, type 2 diabetes, cardiovascular disease, and adverse neonatal outcomes. This study aimed to evaluate th
Lancet Reg Health West Pac. 2026 Mar 4;68:101825. doi: 10.1016/j.lanwpc.2026.101825. eCollection 2026 Mar.ABSTRACTBACKGROUND: The genetic architecture of Parkinson's disease (PD) and progression to PD dementia (PDD) remains incompletely characterized in Asians. Here, we investigated genetic risk fac
medRxiv [Preprint]. 2026 Feb 23:2026.02.21.26346796. doi: 10.64898/2026.02.21.26346796.ABSTRACTHIGHLIGHTS: Atrial fibrillation and depression are linked via central autonomic network disruption, cardiovascular risk, and inflammation.Heightened inflammatory response and cardiovascular risk mediates t
medRxiv [Preprint]. 2026 Feb 25:2026.02.23.26346937. doi: 10.64898/2026.02.23.26346937.ABSTRACTBACKGROUND: Financial strain has been linked to adverse cardiovascular outcomes, yet whether this association persists beyond objective socioeconomic resources remains unclear. We examined associations of
Transl Pediatr. 2026 Feb 28;15(2):44. doi: 10.21037/tp-2025-1-877. Epub 2026 Feb 12.ABSTRACTBACKGROUND: Genetic testing guidelines for children in cardiac intensive care units (CICUs) remain limited despite a high prevalence of genetic diseases among this population. Advances in next-generation sequ
J Clin Transl Endocrinol. 2026 Feb 28;44:100435. doi: 10.1016/j.jcte.2026.100435. eCollection 2026 May.ABSTRACTBACKGROUND: Finerenone, a nonsteroidal mineralocorticoid receptor antagonist, improves renal and cardiovascular outcomes in patients with chronic kidney disease (CKD) and type 2 diabetes (T
Eco Environ Health. 2026 Feb 12;5(1):100224. doi: 10.1016/j.eehl.2026.100224. eCollection 2026 Mar.ABSTRACTThe Planetary Health Diet (PHD) was proposed by the Lancet Commission in 2019. It is a new way of eating that aims to improve both human health and the environment simultaneously. However, rece
Bioact Mater. 2026 Mar 4;62:17-33. doi: 10.1016/j.bioactmat.2026.02.049. eCollection 2026 Aug.ABSTRACTPeriodontitis and myocardial infarction (MI), the leading cause of mortality worldwide, represent globally prevalent inflammatory diseases with bidirectional pathophysiological links. Despite the ur
Bioact Mater. 2026 Mar 4;62:1-16. doi: 10.1016/j.bioactmat.2026.02.040. eCollection 2026 Aug.ABSTRACTMitophagy is a self-protection mechanism for cells to eliminate dysfunctional mitochondria, and maintain mitochondrial homeostasis. Thus, precisely inducing mitophagy represents a promising strategy
Int J Nanomedicine. 2026 Mar 4;21:589123. doi: 10.2147/IJN.S589123. eCollection 2026.ABSTRACTAging is a complex biological process characterized by progressive loss of physiological integrityand represents the primary risk factor for numerous chronic disorders, including neurodegenerative diseases,
Noncoding RNA Res. 2026 Mar 3;19:1-17. doi: 10.1016/j.ncrna.2026.01.006. eCollection 2026 Aug.ABSTRACTBACKGROUND: Diabetes mellitus is a major modifiable risk factor for atherosclerotic cardiovascular disease and pathological vascular remodeling. During chronic hyperglycemia, exosomes serve as essen
Eur J Case Rep Intern Med. 2026 Feb 17;13(3):006244. doi: 10.12890/2026_006244. eCollection 2026.ABSTRACTINTRODUCTION: Kounis syndrome is an acute coronary syndrome precipitated by allergic or hypersensitivity reactions and mediated by the release of inflammatory substances that affect the coronary
J Arrhythm. 2026 Mar 8;42(2):e70308. doi: 10.1002/joa3.70308. eCollection 2026 Apr.ABSTRACTAIMS: Implantable cardioverter-defibrillator (ICD) therapy in children, particularly for primary prevention, remains under investigation, with limited data from less affluent European countries. With increasin
mPAP/V'(O(2)) slope may serve as a noninvasive surrogate of pulmonary exercise haemodynamics predicting both EPH and prognosis in patients at risk for pulmonary vascular disease. Larger prospective studies are needed to validate its clinical utility. https://bit.ly/47Ey1yU.ERJ Open Res. 2026 Mar 9;1
ERJ Open Res. 2026 Mar 9;12(2):00591-2025. doi: 10.1183/23120541.00591-2025. eCollection 2026 Mar.ABSTRACTBACKGROUND AND OBJECTIVE: Recent observational data suggest that cardioselective β-blockers like bisoprolol are safe and beneficial for patients with COPD. However, the acute effects of bisoprol
ERJ Open Res. 2026 Mar 9;12(2):00497-2025. doi: 10.1183/23120541.00497-2025. eCollection 2026 Mar.ABSTRACTRATIONALE: The mechanisms driving epithelial pathology in COPD are steadily being unveiled, confirming a role for inflammation in the disease. This study explored the interleukin (IL)-6/STAT3 ax
Adv Biomed Res. 2026 Jan 30;15:6. doi: 10.4103/abr.abr_140_25. eCollection 2026.ABSTRACTBACKGROUND: Dyslipidemia is a disease and conditions associated with obesity, which is a chronic health problem. The study aimed to determine the 5-year incidence of dyslipidemia in obese and nonobese participant
Transl Androl Urol. 2026 Feb 28;15(2):44. doi: 10.21037/tau-2025-aw-843. Epub 2026 Feb 11.ABSTRACTBACKGROUND: Nocturia is associated with falls, reduced quality of life (QOL), and sleep disturbances, yet remains underdiagnosed and undertreated. Its multifactorial etiology includes reduced bladder ca
Int J Cardiol Heart Vasc. 2026 Mar 3;63:101895. doi: 10.1016/j.ijcha.2026.101895. eCollection 2026 Apr.ABSTRACTBACKGROUND: The management of angiographically intermediate coronary lesions (AICLs) remains challenging. Although current guidelines recommend physiological assessment to guide treatment d
Int J Cardiol Heart Vasc. 2026 Mar 2;63:101899. doi: 10.1016/j.ijcha.2026.101899. eCollection 2026 Apr.ABSTRACTOBJECTIVES: To investigate the association between artificial intelligence (AI)-derived coronary computed tomography angiography (CCTA) features and impaired coronary flow reserve (CFR) in
Clin Kidney J. 2026 Feb 3;19(3):sfag022. doi: 10.1093/ckj/sfag022. eCollection 2026 Mar.ABSTRACTBACKGROUND: Elevated alkaline phosphatase (ALP) levels are associated with mortality. However, the significance of ALP variability, particularly in chronic kidney disease (CKD), has not been well explored
World J Radiol. 2026 Feb 28;18(2):115741. doi: 10.4329/wjr.v18.i2.115741.ABSTRACTBACKGROUND: Non-contrast whole-heart coronary magnetic resonance angiography (CMRA) remains underutilized in clinical practice due to limited visualization of distal vessels and prolonged acquisition times.AIM: To evalu
PeerJ. 2026 Mar 6;14:e20489. doi: 10.7717/peerj.20489. eCollection 2026.ABSTRACTBACKGROUND: The matrix metalloproteinase-2 (MMP2) rs243865 polymorphism has been associated with cardiovascular events; however, its impact on difficult-to-control hypertension remains unclear. This study aims to assess
