Retinal Neurophysiological Parameters in Young Patients With Type 1 Diabetes

Invest Ophthalmol Vis Sci. 2026 May 1;67(5):3. doi: 10.1167/iovs.67.5.3.ABSTRACTPURPOSE: Diabetic retinopathy has prominent microvascular manifestations, but preclinical studies also find neuroglial cell abnormalities. This study aimed to examine retinal electrophysiological characteristics and thei

M Marie Elise Wistrup Torm

Congestion and renal function in patients with chronic heart failure

ESC Heart Fail. 2026 May 4:xvag126. doi: 10.1093/eschf/xvag126. Online ahead of print.ABSTRACTBACKGROUND: Cardiac and renal dysfunction often conspire to cause water and salt retention. We assessed the relation between renal function and congestion, both clinically and by ultrasound, in chronic hear

A Ahmad Alsaeed

An ICF framework analysis of the CVID quality of life questionnaire

Disabil Rehabil. 2026 May 4:1-12. doi: 10.1080/09638288.2026.2662748. Online ahead of print.ABSTRACTPURPOSE: This study aimed to link the Common Variable Immune Deficiency Quality of Life (CVID-QoL) and Short Form-36 (SF-36) questionnaires to the International Classification of Functioning, Disabili

E Ecran Cinkavuk

AlphaFold3-guided tracrRNA redesign yields small monomeric Cas12f RNPs

Nucleic Acids Res. 2026 Apr 23;54(8):gkag430. doi: 10.1093/nar/gkag430.ABSTRACTAlthough Cas12f (Cas14) is among the smallest Class 2 CRISPR (clustered regularly interspaced short palindromic repeats) effectors, it assembles into dimeric ribonucleoprotein (RNP) complexes with guide RNA, substantially

L Lulu Pan

Piperazine-Derived Diamine Lipid Nanoparticles Targeting to the Liver for Delivering Clustered Regularly Interspaced Short Palindromic Repeat Editing of PCSK9 to Durably Maintain Plasmatic Low-Density Lipoprotein Cholesterol in Low Levels

ACS Appl Bio Mater. 2026 May 4. doi: 10.1021/acsabm.6c00032. Online ahead of print.ABSTRACTCardiovascular diseases remain a leading cause of morbidity and mortality worldwide, and durable suppression of low-density lipoprotein cholesterol (LDL-C) via genome editing represents a promising therapeutic

S Shifeng Zhao