Factors associated with adherence to allocated treatment in the ASCEND trial: a mail-based randomised trial of aspirin and of omega-3 fatty acid supplementation in people with diabetes

Trials. 2026 Feb 27;27(1):183. doi: 10.1186/s13063-026-09551-4.ABSTRACTINTRODUCTION: ASCEND assessed the effects of randomisation to aspirin versus placebo and, separately omega-3 fatty acid (FA) supplementation versus placebo on vascular events in 15480 adults with diabetes using mail-based remote

V Vichithranie W Madurasinghe

Senolytics and exercise: Dual modalities for rejuvenating muscle

J Physiol. 2026 Feb 26. doi: 10.1113/JP287702. Online ahead of print.ABSTRACTMammalian ageing is defined as a gradual loss of the capacity to maintain tissue homeostasis or to repair tissues after injury or stress. Cellular senescence is induced by various cellular stressors, and there is accumulati

Z Zeynep Elif Yesilyurt-Dirican

Acute rheumatic fever and rheumatic heart disease

Nat Rev Dis Primers. 2026 Feb 26;12(1):7. doi: 10.1038/s41572-026-00685-y.ABSTRACTAcute rheumatic fever (ARF), the acute autoimmune sequela of group A Streptococcus infection, and its chronic life-threatening manifestation, rheumatic heart disease (RHD), which causes permanent heart valve damage, re

L Liesl Zühlke