Echocardiographic effects of medetomidine, butorphanol, and their combination in donkeys

BMC Vet Res. 2026 Jul 4. doi: 10.1186/s12917-026-05678-3. Online ahead of print.ABSTRACTBACKGROUND: Standing sedation is frequently required in donkeys for minor surgical and diagnostic procedures, yet information on the cardiac safety of α2-adrenoceptor agonists and opioid combinations in this spec

M Marwa Abass

Synergistic SGLT2 and GLP-1R targeting alleviates systemic inflammation-induced and M1 monocyte-driven endothelial dysfunction in coronary artery disease

Cardiovasc Diabetol. 2026 Jul 4. doi: 10.1186/s12933-026-03267-0. Online ahead of print.ABSTRACTBACKGROUND AND OBJECTIVE: Systemic residual inflammation plays a pivotal role in the pathophysiology of coronary artery disease (CAD). Cardiovascular protection by SGLT2 inhibitors (SGLT2i) and GLP-1 rece

A Ali Mroueh

Comparative performance of insulin resistance-related indices in predicting adverse cardiovascular events among individuals with NAFLD and MASLD: a multi-center cohort study

Cardiovasc Diabetol. 2026 Jul 4. doi: 10.1186/s12933-026-03208-x. Online ahead of print.ABSTRACTBACKGROUND: Metabolic dysfunction-associated steatotic liver disease (MASLD) and non-alcoholic fatty liver disease (NAFLD) are closely linked to insulin resistance and elevated cardiovascular risk, trigly

Y Yanqiu Huang

Driving NCD screening at scale: outcomes of a digital, CHW-led hypertension surveillance program in rural Rwanda

BMC Public Health. 2026 Jul 4. doi: 10.1186/s12889-026-28330-z. Online ahead of print.ABSTRACTBACKGROUND: Hypertension is the leading risk factor for cardiovascular diseases, with the greatest burden in low- and middle-income countries where access to care and infrastructure for prevention and manag

E Evariste Ntaganda

Elevated plasma TMAO levels associated with all-cause mortality in CAD patients in South China

BMC Cardiovasc Disord. 2026 Jul 4. doi: 10.1186/s12872-026-06214-9. Online ahead of print.ABSTRACTBACKGROUND: Coronary artery disease (CAD) is a prevalent cardiovascular condition worldwide. Trimethylamine N-oxide (TMAO), a metabolite produced by gut microbiota, plays a crucial role in the pathogene

H Hao Zhang

A novel berberine derivative B12 exhibits superior anti-obesity effects via targeting brown and white adipocyte dynamics

Int J Obes (Lond). 2026 Jul 4. doi: 10.1038/s41366-026-02153-9. Online ahead of print.ABSTRACTBACKGROUND: Obesity remains a global health challenge, with limited therapeutic options. Berberine (BBR) shows promise as an anti-obesity agent. However, its clinical application is hampered by modest effic

W Wenqing Zhang

Improving arrhythmic risk prediction using cardiac magnetic resonance within deep learning in ischemic heart disease

NPJ Cardiovasc Health. 2026 Jul 5. doi: 10.1038/s44325-026-00142-5. Online ahead of print.ABSTRACTSudden arrhythmic death remains a major clinical risk in ischemic heart disease (IHD), underscoring the need for improved risk stratification. Late gadolinium enhancement cardiac magnetic resonance (LGE

A Ahmet Sen

Heart failure promotes gingival inflammation and impairs periodontal remodeling

Sci Rep. 2026 Jul 4;16(1):20556. doi: 10.1038/s41598-026-58806-2.ABSTRACTObservational studies suggest an association between impaired oral health and cardiovascular disease; however, the directionality and underlying mechanisms remain unclear. In particular, whether heart failure (HF) itself advers

M Martin Berger

Joint trajectories of brain atrophy, white matter hyperintensities and cognition quantify brain maintenance

Nat Commun. 2026 Jul 4;17(1):5846. doi: 10.1038/s41467-026-74957-2.ABSTRACTBrain maintenance - the preservation of brain structure or function relevant to cognitive performance - remains challenging to quantify. Here, we propose a domain-general brain maintenance index derived by jointly modelling t

I Inga Menze

Multi-ancestry gene expression models amplify transcriptome-wide association study discovery and validation

Nat Commun. 2026 Jul 4. doi: 10.1038/s41467-026-75193-4. Online ahead of print.ABSTRACTOur understanding of the influence of ancestral background on genetically determined expression remains limited, especially when gene expression models are applied to studies from different or multiple populations

X Xavier Bledsoe

Metabolic Syndrome in Musculoskeletal Practice: Clinical and Social Features

Musculoskeletal Care. 2026 Sep;24(3):e70235. doi: 10.1002/msc.70235.ABSTRACTINTRODUCTION: Metabolic syndrome is a well-established cluster of cardiovascular risk factors with increasing relevance to musculoskeletal pain, function, and rehabilitation. Beyond its recognised effects on cardiovascular h

N Neil Langridge

Renal Dysfunction Modifies the Prognostic Value of Lactate Clearance in Extracorporeal Cardiopulmonary Resuscitation: A Retrospective Interaction Analysis

J Cardiothorac Vasc Anesth. 2026 Jun 10:S1053-0770(26)00490-8. doi: 10.1053/j.jvca.2026.06.013. Online ahead of print.ABSTRACTOBJECTIVES: To test whether renal dysfunction modifies the prognostic value of 24-hour lactate clearance for survival to discharge after extracorporeal cardiopulmonary resusc

T Taekwon Kim

Impact of icosapent ethyl on serum lipoand glycoprotein profiles assessed by 1H-NMR. A real-world observational study (IPE-NMR)

Nutr Metab Cardiovasc Dis. 2026 Jun 24:104852. doi: 10.1016/j.numecd.2026.104852. Online ahead of print.ABSTRACTBACKGROUND AND AIM: Icosapent-ethyl (IPE) has been shown to reduce cardiovascular events in a randomized trial; however, its real-world impact on advanced lipoprotein and inflammatory prof

N Núria Amigó

A dual-modal RPA-CRISPR/Cas12a biosensor for rapid and ultrasensitive detection of Staphylococcus aureus in bloodstream infections

Anal Chim Acta. 2026 Sep 22;1416:345800. doi: 10.1016/j.aca.2026.345800. Epub 2026 Jun 6.ABSTRACTBACKGROUND: Bloodstream infections (BSIs) caused by Staphylococcus aureus (S. aureus) require rapid and accurate diagnosis to guide effective antimicrobial therapy and improve patient outcomes. However,

G Gaoming Luo

CAD-RADS 2.0 - Update on the evaluation and management of coronary artery disease with coronary CT angiography

Radiologia (Engl Ed). 2026 Jul-Aug;68(4):501689. doi: 10.1016/j.rxeng.2026.501689. Epub 2026 May 11.ABSTRACTThe updated Coronary Artery Disease Reporting and Data System (CAD-RADS 2.0) adds new features for patients undergoing coronary CT angiography (CCTA). The following features are included in th

M M Jiménez Vázquez

Basilar thrombolysis in cerebral infarction (bTICI) scale: Proposal and preliminary validation of a basilar reperfusion score based on digital subtraction angiography to evaluate the efficacy of mechanical thrombectomy in acute basilar artery occlusion

Radiologia (Engl Ed). 2026 Jul-Aug;68(4):501803. doi: 10.1016/j.rxeng.2026.501803. Epub 2026 Feb 13.ABSTRACTOBJECTIVES: Basilar artery occlusion (BAO) accounts for 10% of all ischemic strokes due to largevessel occlusion (LVO) and is associated with highest mortality and disability rate. The aim oft

A A López-Rueda

Serum sialic acid is independently associated with cerebrovascular atherosclerotic stenosis severity and total vascular burden: A retrospective cohort study

Clin Chim Acta. 2026 Jul 4:121217. doi: 10.1016/j.cca.2026.121217. Online ahead of print.ABSTRACTBACKGROUND: Atherosclerosis (AS) is still the major cause of cerebrovascular atherosclerotic stenosis (CAS). Sialic acid (SA) has garnered significant attention in atherosclerosis research. Some clinical

Q Qi Cai

Cardiovascular maladaptation in women with hypertensive disorders of pregnancy and long-term cardiovascular risk

Am J Obstet Gynecol MFM. 2026 Jul 4:102051. doi: 10.1016/j.ajogmf.2026.102051. Online ahead of print.ABSTRACTHypertensive disorders of pregnancy (HDP) are a leading cause of maternal and perinatal morbidity and mortality. Pregnancy is increasingly viewed as a physiological "stress test" capable of r

J Jing Lin

High Rates of Permanent Pacemaker Implantation After Left-Sided Cardiac Surgery in Adults with Congenital Heart Disease

No abstractHeart Rhythm. 2026 Jul 4:S1547-5271(26)02481-1. doi: 10.1016/j.hrthm.2026.06.014. Online ahead of print.NO ABSTRACTPMID:42401379 | DOI:10.1016/j.hrthm.2026.06.014

R Ramses Delgadillo

Association of Toothbrushing, Dental Flossing, and Interdental Brushing with Stroke Risk

J Dent. 2026 Jul 4:106882. doi: 10.1016/j.jdent.2026.106882. Online ahead of print.ABSTRACTOBJECTIVES: Stroke is the second leading cause of death globally. While daily toothbrushing is widely promoted for oral hygiene, the preventive impact of adjunctive oral hygiene practices, such as dental floss

S Sangwoo Park

Clinical and Radiographic Sex Related Difference in Patients with Acute Type B and Non-A Non-B Aortic Dissections

Eur J Vasc Endovasc Surg. 2026 Jul 4:S1078-5884(26)00672-6. doi: 10.1016/j.ejvs.2026.06.056. Online ahead of print.ABSTRACTOBJECTIVE: The aim of this study was to evaluate clinical and radiographic differences between men and women with acute type B aortic dissection (TBAD) and non-A non-B aortic di

M Magdalena Bork

Endogenous-metabolite-inspired polyamine-oleic acid lipids for safe mRNA delivery and PCSK9 gene editing

J Control Release. 2026 Jul 4:115159. doi: 10.1016/j.jconrel.2026.115159. Online ahead of print.ABSTRACTLipid nanoparticles (LNPs) are widely used for nucleic acid delivery but often rely on synthetic ionizable cationic lipids that pose concerns regarding immunogenicity, metabolic compatibility, and

X Xiao Hou

Heart Failure Pharmacotherapy Across the TAVR Continuum

J Card Fail. 2026 Jul 4:S1071-9164(26)00374-X. doi: 10.1016/j.cardfail.2026.06.011. Online ahead of print.ABSTRACTTake Home Illustration. Heart Failure Pharmacotherapy Across the TAVR Continuum. GDMT recommendations across the pre-, peri-, and post-procedural phases of TAVR. The recommendations are

T Takayuki Onishi

Does prior percutaneous coronary revascularization negatively affect the outcomes of subsequent coronary artery bypass grafting?

Ann Thorac Surg. 2026 Jul 4:S0003-4975(26)00705-8. doi: 10.1016/j.athoracsur.2026.06.052. Online ahead of print.ABSTRACTBACKGROUND: The growing use of percutaneous coronary intervention (PCI) has led to an increasing number of patients referred for coronary artery bypass grafting (CABG) after prior

V Vittoria Lodo