Feasibility of multimodal metabolic analysis for detecting early changes in acute neuroinflammation

J Neuroinflammation. 2026 May 4. doi: 10.1186/s12974-026-03839-7. Online ahead of print.ABSTRACTGiven the prevalence of metabolic perturbations in a variety of neurological and neurodegenerative diseases, understanding and monitoring brain metabolism is a key step in our advancement of therapies. Th

J James T Grist

The relationship of neutrophil to high-density lipoprotein cholesterol ratio with all-cause mortality in patients undergoing cardiac surgery: a retrospective cohort study

J Cardiothorac Surg. 2026 May 3. doi: 10.1186/s13019-026-04195-6. Online ahead of print.ABSTRACTBACKGROUND: The mortality following cardiac surgery remains high. The neutrophil-to-high-density lipoprotein cholesterol ratio (NHR) is a marker that reflects both inflammation and metabolic status, and i

Z Zehan Guo

The role of bempedoic acid in the management of dyslipidaemia in people with diabetes: an expert opinion of Italian diabetologists

Cardiovasc Diabetol. 2026 May 3. doi: 10.1186/s12933-026-03185-1. Online ahead of print.ABSTRACTDiabetes mellitus is a rapidly growing global health challenge and a major driver of atherosclerotic cardiovascular disease (ASCVD). Dyslipidaemia, highly prevalent in both type 1 and type 2 diabetes, pla

M Massimo Federici

Cadmium impairs heart ventricular formation and disrupts polysialylated-NCAM/FGF receptor signaling in Xenopus tadpoles

Cell Biosci. 2026 May 3. doi: 10.1186/s13578-026-01579-y. Online ahead of print.ABSTRACTBACKGROUND: Exposure to cadmium, a trace metallic element, is a major health concern. Cadmium is associated with a higher risk and predisposition to cardiovascular disease. Identifying molecular targets involved

P Pélagie Douchez

Association between dietary patterns and CAIDE-predicted dementia risk: A 20-year cohort of the Korean Genome and Epidemiology study

Geroscience. 2026 May 4. doi: 10.1007/s11357-026-02288-7. Online ahead of print.ABSTRACTThis study examined associations between dietary habits and the risk of developing Cardiovascular Risk Factors, Aging, and Incidence of Dementia (CAIDE)-predicted late-life dementia risk in Korean adults. A total

J Ji-Eun Youn

Microstructural changes in memory-related brain regions of stroke-free patients with middle cerebral artery occlusion as revealed by diffusion spectrum imaging

Brain Imaging Behav. 2026 May 4;20(3):87. doi: 10.1007/s11682-026-01160-8.ABSTRACTWe used diffusion spectrum imaging (DSI) and 3-dimensional arterial spin labeling to investigate microstructural and perfusion changes in memory-related brain regions in stroke-free patients with middle cerebral artery

Z Zhenghua Liu

C-reactive protein-triglyceride glucose index as a predictor of heart failure risk in adults with MASLD: a prospective cohort study

Sci Rep. 2026 May 3. doi: 10.1038/s41598-026-51503-0. Online ahead of print.ABSTRACTHeart failure (HF) is a major complication of metabolic dysfunction-associated steatotic liver disease (MASLD). The C-reactive protein-triglyceride glucose index (CTI), which reflects systemic inflammation and insuli

H Haixiang Zheng

Multicenter reference limits of hs-cTnI and NT-proBNP in a Chinese cohort

Diagnosis (Berl). 2026 May 5. doi: 10.1515/dx-2026-0045. Online ahead of print.ABSTRACTOBJECTIVES: This study aimed to validate the analytical performance of high-sensitivity cardiac troponin I (hs-cTnI) and N-terminal pro-B-type natriuretic peptide (NT-proBNP) assays, and to establish age- and sex-

Y Yuxin Xu

Survival and Clinical Progression in Barth Syndrome: Insights From the Barth Syndrome Foundation's Database of 502 Affected Individuals

J Inherit Metab Dis. 2026 May;49(3):e70189. doi: 10.1002/jimd.70189.ABSTRACTBarth syndrome (BTHS; OMIM 302060) is an ultra-rare, life-limiting genetic disorder characterized by cardiomyopathy, skeletal muscle myopathy, neutropenia, gastrointestinal issues, and fatigue. Formal analyses of survival an

K Kexin Fu

Bempedoic acid and increased serum uric acid levels: a matter of concern?

Nutr Metab Cardiovasc Dis. 2026 Apr 11:104755. doi: 10.1016/j.numecd.2026.104755. Online ahead of print.ABSTRACTAIMS: Several observational and genetic studies have found an association between high urate serum levels and hypertension, heart failure, and cardiovascular mortality. Bempedoic acid is a

L Luca Bonanni

Recommendations for the Identification and Mitigation of Cardiac Ultrasound Artifacts: A Guideline from the American Society of Echocardiography

J Am Soc Echocardiogr. 2026 May;39(5):435-475. doi: 10.1016/j.echo.2026.01.007.ABSTRACTAn ultrasound artifact is a feature in an ultrasound image that does not accurately represent the true anatomy or pathology. Cardiac ultrasound artifacts are common and inevitable findings as they originate from t

M Muhamed Saric

Insights into Semaglutide Cardiovascular Research: Mechanisms, Trials, and Frontiers

Eur J Pharmacol. 2026 May 1:178921. doi: 10.1016/j.ejphar.2026.178921. Online ahead of print.ABSTRACTCardiovascular disease (CVD) remains the leading cause of global mortality, with pathophysiological alterations such as heart failure with preserved ejection fraction, diabetic cardiomyopathy, and at

J Jiexin Zhang

Do epigenetic aging biomarkers mediate the association between exposure and health outcomes? A scoping review of mediation analysis

Environ Res. 2026 May 1:124600. doi: 10.1016/j.envres.2026.124600. Online ahead of print.ABSTRACTEpigenetic aging biomarkers are promising novel biological age indicators derived from algorithms based on DNA methylation patterns. Since epigenetic age was first described over a decade ago, it has bee

R Ryosuke Fujii

Dynamic aortic stiffness response to exercise as a marker of functional capacity in early-stage heart failure

Clin Physiol Funct Imaging. 2026 May;46(3):e70066. doi: 10.1111/cpf.70066.ABSTRACTOBJECTIVES: Aortic stiffness increases ventricular afterload and limits exercise capacity in heart failure (HF), but its dynamic response to exercise remains insufficiently defined. This study aimed to evaluate exercis

M Mustafa Ferhat Keten

Multimodal neurophysiological responses during a counteractive motion task in preschool children

Acta Psychol (Amst). 2026 May 2;266:106970. doi: 10.1016/j.actpsy.2026.106970. Online ahead of print.ABSTRACTBACKGROUND: Cognitive control develops rapidly during the preschool years, but its multimodal neurophysiological correlates remain incompletely understood. The present study examined age-rela

H Haiqi Xiang

Joint association of physical activity and tea consumption with all-cause and cause-specific mortality: The Rural Chinese Cohort Study

Public Health. 2026 May 2;256:106318. doi: 10.1016/j.puhe.2026.106318. Online ahead of print.ABSTRACTOBJECTIVES: This study aimed to examine the independent and joint associations of physical activity (PA) and tea consumption with mortality risk.STUDY DESIGN: The Rural Chinese Cohort Study.METHODS:

S Shuoshuo Li

Gaps in Incidence and Design of Peripheral versus Coronary Artery Disease Clinical Trials

J Surg Res. 2026 May 2;323:24-32. doi: 10.1016/j.jss.2026.03.113. Online ahead of print.ABSTRACTINTRODUCTION: Atherosclerotic cardiovascular diseases, with peripheral artery disease (PAD) and coronary artery disease (CAD) being the most common, are leading causes of morbidity and mortality. Although

K Katherine M Reitz

Machine learning-based cardiovascular risk prediction in systemic lupus erythematosus: development and internal validation of a prognostic model

J Autoimmun. 2026 May 2;161:103561. doi: 10.1016/j.jaut.2026.103561. Online ahead of print.ABSTRACTBACKGROUND: Cardiovascular (CV) diseases are the leading cause of mortality in patients with systemic lupus erythematosus (SLE). While traditional risk factors inadequately assess CV risk, SLE-specific

N Noémie Benonnier

Applications of Metabolomics in the Development of Biomedicine and Biotechnology

Adv Exp Med Biol. 2026;1504:431-459. doi: 10.1007/978-3-032-18966-0_21.ABSTRACTMetabolomics has emerged as a powerful discipline for capturing dynamic biochemical states and linking molecular processes to human health, disease, and biotechnology. This chapter explores the evolution of metabolomics f

E Eric H Rosenn

Revisiting the role of beta blockers in the management of hypertension

Curr Opin Cardiol. 2026 May 4. doi: 10.1097/HCO.0000000000001303. Online ahead of print.ABSTRACTPURPOSE OF REVIEW: Although beta blockers have a long history in hypertension management, their first-line role remains controversial after early-2000 s trials raised concerns about inferior stroke preven

T Takeshi Fujiwara

Parameters of Delayed Neuroinflammation Following Focal Ischemic Stroke in the Mouse Cerebral Cortex Depend on Lesion Size at the Beginning of the Subacute Stage

Biochemistry (Mosc). 2026 Apr;91(4):588-600. doi: 10.1134/S0006297925604009.ABSTRACTDynamics of glial activity changes in the subacute and chronic stages of ischemic stroke after small focal injuries remains poorly understood due to complexity of the long-term animal monitoring and data interpretati

V Vyacheslav I Alekseev

Dialysis, but not severe renal dysfunction, is associated with excess bleeding in venous thromboembolism: Insights from a nationwide registry

No abstractEur J Intern Med. 2026 May 2:106927. doi: 10.1016/j.ejim.2026.106927. Online ahead of print.NO ABSTRACTPMID:42070958 | DOI:10.1016/j.ejim.2026.106927

T Takahiro Kuno

Chronic Chagas disease and type 2 diabetes comorbidity. The scenario in which two differently driven inflammatory mechanisms meet

Semin Immunol. 2026 May 2;82:102028. doi: 10.1016/j.smim.2026.102028. Online ahead of print.ABSTRACTChagas disease (ChD) and Type 2 diabetes (T2D) originate from distinct etiological processes -infectious and metabolic, respectively- yet both share a chronic inflammatory and metabolic imbalance that

B Brenda Dinatale

Complementary strategies in Psoriasis - non-pharmacological approaches for comprehensive management

An Bras Dermatol. 2026 May 2;101(3):501356. doi: 10.1016/j.abd.2026.501356. Online ahead of print.ABSTRACTBACKGROUND: Psoriasis is a chronic immune-mediated inflammatory disease linked to systemic comorbidities such as obesity, diabetes, cardiovascular disease, and inflammatory bowel disease. Non-ph

F Fernando Valenzuela