Finerenone-Based Dual Versus Triple Therapy with SGLT2 Inhibitors and GLP-1 Receptor Agonists in Type 2 Diabetes Mellitus Associated Chronic Kidney Disease: A Retrospective Cohort Study

Clin Ther. 2026 Sep 8:S0149-2918(26)00305-X. doi: 10.1016/j.clinthera.2026.08.004. Online ahead of print.ABSTRACTPURPOSE: Finerenone reduces Cardiovascular-Kidney-Metabolic (CKM) risk in type 2 diabetes mellitus (T2DM)-related chronic kidney disease (CKD). Evidence on its combined use with sodium-gl

M Mohammed Khogalee

Butylphthalide combined with tenecteplase in mild disabling acute ischaemic stroke in China (BENEFIT-2): study protocol for a multicentre, randomised, double-blind, active-controlled trial

BMJ Open. 2026 Sep 8;16(9):e119290. doi: 10.1136/bmjopen-2026-119290.ABSTRACTINTRODUCTION: Intravenous thrombolysis is the standard early treatment for acute ischaemic stroke (AIS), yet a substantial proportion of patients, particularly those with mild disabling deficits, do not achieve favourable f

Q Qiaoling Tang

Clinical and multi-omics characterisation of early neurodevelopmental disorders associated with critical congenital heart disease: the prospective cohort CATAMARAN neonatal study protocol

BMJ Open. 2026 Sep 8;16(9):e116866. doi: 10.1136/bmjopen-2026-116866.ABSTRACTINTRODUCTION: Critical congenital heart disease (CHD) is associated with neurodevelopmental disorders, recognised as the most common long-term morbidity in affected children. In critical CHD, that is, CHD requiring cardiac

O Oscar Werner

Differences in associations between long-acting injectable and oral antipsychotic prescribing and healthcare utilisation in people with intellectual disability: a self-controlled case series (LOID study)

BMJ Ment Health. 2026 Sep 8;29(1):e302830. doi: 10.1136/bmjment-2026-302830.ABSTRACTBACKGROUND: Literature guiding the use of long-acting injectable antipsychotics (LAIAs) versus oral antipsychotics (OAs) in people with intellectual disability (PWID) remains scarce.OBJECTIVE: Examining the associati

S Shek Ming Leung

Heart Transplantation in 2076: From Scarcity to Cardiac Restoration

J Card Fail. 2026 Sep;32(9):1656-1659. doi: 10.1016/j.cardfail.2026.05.020.ABSTRACTHeart transplantation has historically been defined by the scarcity of donor organs and the uncertainties surrounding them. Over the past 50 years, advances in immunosuppression, surgical techniques, and posttransplan

H Hannah Valantine

Heart Transplantation in 2076: Evolution, Transformation, or Obsolescence?

J Card Fail. 2026 Sep;32(9):1647-1651. doi: 10.1016/j.cardfail.2026.03.034.ABSTRACTHeart transplantation has transformed survival in end-stage heart failure but remains constrained by donor scarcity, lifelong immunosuppression, and late graft-related morbidity. Over the next 5 decades, converging ad

M Mandeep R Mehra