Stem cell models in ataxia-telangiectasia

Neural Regen Res. 2025 Dec 30. doi: 10.4103/NRR.NRR-D-25-00988. Online ahead of print.ABSTRACTAtaxia-telangiectasia is a rare neurodegenerative disease with a complex phenotype, which has recently been associated with alterations in metabolism, inadequate responses to oxidative stress and inflammati

M Maria Talmon

State-Level Structural Racism and Incident Coronary Heart Disease

J Am Heart Assoc. 2025 Dec 30:e039828. doi: 10.1161/JAHA.124.039828. Online ahead of print.ABSTRACTBACKGROUND: Black Americans have greater coronary heart disease (CHD) burden than White Americans, disparities that are largely socially determined. Discriminatory societal practices that systematicall

M Monika M Safford

Yin-Yang 1/Neural Precursor Cell-Expressed Developmentally Downregulated 4-Like Axis Suppresses Mer Tyrosine Kinase-Mediated Macrophage Efferocytosis to Exacerbate Atherosclerosis Via Triggering Pyroptosis

J Am Heart Assoc. 2025 Dec 30:e039855. doi: 10.1161/JAHA.124.039855. Online ahead of print.ABSTRACTBACKGROUND: Atherosclerosis is considered as a major contributor for cardiovascular disease with high morbidity and mortality globally. However, the cross-talk between efferocytosis and inflammation in

Q Qiang Liu

Emerging methods for subtype differentiation in primary aldosteronism

J Intern Med. 2025 Dec 30. doi: 10.1111/joim.70055. Online ahead of print.ABSTRACTPrimary aldosteronism (PA) is a common cause of hypertension. Compared to patients with essential hypertension, untreated PA is associated with a two- to fourfold greater risk of cardiovascular disease, renal failure,

O Oskar Ragnarsson

Mechanisms Linking Insomnia and Cardiometabolic Disease Risk

Arterioscler Thromb Vasc Biol. 2025 Dec 30. doi: 10.1161/ATVBAHA.125.322880. Online ahead of print.ABSTRACTAbout 10% to 15% of the adult population reports frequent, chronic insomnia symptoms of difficulty initiating or maintaining sleep associated with daytime impairment (ie, insomnia disorder). An

J Julio Fernandez-Mendoza

Copeptin as a prognostic biomarker in heart failure: a comprehensive review

Folia Med (Plovdiv). 2025 Nov 28;67(6). doi: 10.3897/folmed.67.e153542.ABSTRACTHeart failure (HF) poses a major global health burden due to its high prevalence, complexity, and poor prognosis. Although biomarkers such as B-type natriuretic peptides (BNP, NT-proBNP) are widely used for diagnosis and

M Machineni Sravani