Drug Metab Dispos. 2026 Jun 29;54(8):100352. doi: 10.1016/j.dmd.2026.100352. Online ahead of print.ABSTRACT10-Hydroxyl mesaconitine (10-OH MA) is a new potential toxicity marker of Radix Aconiti Lateralis Preparata (Fuzi), which is widely used for the treatment of cardiovascular diseases, rheumatoid
JACC Adv. 2026 Jul 15;5(8):103010. doi: 10.1016/j.jacadv.2026.103010. Online ahead of print.ABSTRACTBACKGROUND: Intravascular lithotripsy (IVL) has been demonstrated effective and safe in the treatment of balloon-crossable calcified coronary lesions. However, a significant subset of patients still e
JACC Adv. 2026 Jul 15;5(8):103004. doi: 10.1016/j.jacadv.2026.103004. Online ahead of print.ABSTRACTBACKGROUND: Current guidelines for patients with atherosclerotic cardiovascular disease (ASCVD) have explicitly highlighted the direct correlation of reduced low-density lipoprotein cholesterol (LDL-C
Clin Imaging. 2026 Jul 13;138:110899. doi: 10.1016/j.clinimag.2026.110899. Online ahead of print.ABSTRACTBACKGROUND: Coronary plaque characteristics, rather than luminal stenosis, are important determinants of cardiovascular risk. The role of pericardial fat in non-stenotic coronary artery disease (
No abstractN Engl J Med. 2026 Jul 16;395(3):304-305. doi: 10.1056/NEJMe2604885.NO ABSTRACTPMID:42456142 | DOI:10.1056/NEJMe2604885
N Engl J Med. 2026 Jul 16;395(3):233-242. doi: 10.1056/NEJMoa2517588.ABSTRACTBACKGROUND: Patients with multivessel coronary artery disease often receive 12 months of dual antiplatelet therapy (DAPT) after stenting to reduce the risk of ischemic events. Whether extending DAPT beyond 12 months in even
Nano Lett. 2026 Jul 15. doi: 10.1021/acs.nanolett.6c01815. Online ahead of print.ABSTRACTEffective management of acute lung injury (ALI) necessitates both prolonged pulmonary retention and precise immune modulation. Here, we report a novel bioadhesive piezoelectric immunomodulator (PNS@PDA), designe
NEJM Catal Innov Care Deliv. 2026;7(s1):CAT250256. doi: 10.1056/CAT.25.0256. Epub 2026 Mar 18.ABSTRACTElectrocardiogram (ECG) interpretation is fundamental to cardiovascular care, yet persistent human variability and escalating diagnostic demands hinder its reliability and scalability. Despite the r
Sci Adv. 2026 Jul 17;12(29):eaec8501. doi: 10.1126/sciadv.aec8501. Epub 2026 Jul 15.ABSTRACTMacrophages are key drivers of inflammatory and fibrotic diseases, and their activation is shaped by interactions in their tissue microenvironment. However, dissecting the processes that drive immunopathology
Diabetes Metab Res Rev. 2026 Jul;42(5):e70202. doi: 10.1002/dmrr.70202.ABSTRACTOBJECTIVE: To evaluate the atrial fibrillation (AF) risk of sodium-glucose cotransporter-2 inhibitors (SGLT-2i), glucagonlike peptide-1 receptor agonists (GLP-1RA) and dipeptidyl peptidase-4 inhibitors (DPP-4i) in patient
Physiother Res Int. 2026 Jul;31(3):e70290. doi: 10.1002/pri.70290.ABSTRACTBACKGROUND: Post-stroke shoulder pain (PSSP) is a common complication that negatively affects functional recovery and rehabilitation outcomes. Despite the availability of evidence-informed management strategies, clinical pract
Sci Transl Med. 2026 Jul 15;18(858):eadv4095. doi: 10.1126/scitranslmed.adv4095. Epub 2026 Jul 15.ABSTRACTVenous leg ulcers (VLUs) are the most common cause of leg ulcers, yet only 44% heal with standard-of-care treatment, highlighting the critical need for better understanding of their cellular pat
Sci Transl Med. 2026 Jul 15;18(858):eadv1815. doi: 10.1126/scitranslmed.adv1815. Epub 2026 Jul 15.ABSTRACTAtherosclerotic cardiovascular disease (ASCVD) remains a leading cause of morbidity and mortality in patients with insulin resistance, and new therapies are urgently needed. We previously develo
PLoS One. 2026 Jul 15;21(7):e0353683. doi: 10.1371/journal.pone.0353683. eCollection 2026.ABSTRACTBACKGROUND: Stroke, a leading cause of global mortality and disability, requires accurate prediction of discharge outcomes to support early care planning. We developed an explainable artificial intellig
PLoS One. 2026 Jul 15;21(7):e0351837. doi: 10.1371/journal.pone.0351837. eCollection 2026.ABSTRACTOBJECTIVE: Short-term residential care (STRC) is a Dutch form of post-acute care intended to return older adults home to live independently, yet fewer than 55% of patients are discharged home. Because p
PLOS Glob Public Health. 2026 Jul 15;6(7):e0006376. doi: 10.1371/journal.pgph.0006376. eCollection 2026.ABSTRACTSeasonal respiratory infections typically surge within a limited time window, but what determines the exact timing within a given year is not well understood. Major causes of death show a
Eur Heart J. 2026 Jul 15:ehag489. doi: 10.1093/eurheartj/ehag489. Online ahead of print.ABSTRACTBACKGROUND AND AIMS: Abdominal aortic aneurysms (AAAs) are associated with increased mortality in older adults. The gut microbe-generated metabolite trimethylamine N-oxide (TMAO) has been linked to AAA ri
Obes Facts. 2026 Jul 15:1-15. doi: 10.1159/000552188. Online ahead of print.ABSTRACTINTRODUCTION: The relationship between sleep disordered breathing (SDB), bone mineral density (BMD) and risk of osteoporosis is unclear. Obesity, a condition often comorbid with SDB, has been associated with high BMD
Pol Arch Intern Med. 2026 Jul 15:17351. doi: 10.20452/pamw.17351. Online ahead of print.ABSTRACTPatients undergoing maintenance hemodialysis face annual mortality rates of 15-27%, with cardiovascular causes accounting for more than half of all deaths. Despite advances in dialytic technology, convent
Eur Heart J. 2026 Jul 15:ehag089. doi: 10.1093/eurheartj/ehag089. Online ahead of print.ABSTRACTPatients with cancer usually report limitations of their functional capacity, which may range from subclinical impairment of cardiopulmonary exercise reserve to poor quality of life with physical, cogniti
JAMA Cardiol. 2026 Jul 15. doi: 10.1001/jamacardio.2026.2435. Online ahead of print.ABSTRACTIMPORTANCE: Ischemic heart disease (IHD), the leading cause of death in the US, is predominantly due to modifiable risk factors. Estimates of IHD mortality attributable to risk factors provide evidence for he
JAMA Cardiol. 2026 Jul 15. doi: 10.1001/jamacardio.2026.2314. Online ahead of print.ABSTRACTIMPORTANCE: Although the Martin-Hopkins equation is widely validated and used to estimate low-density lipoprotein cholesterol (LDL-C) for clinical care, a simplified equation could streamline implementation a
No abstractJAMA Cardiol. 2026 Jul 15. doi: 10.1001/jamacardio.2026.2059. Online ahead of print.NO ABSTRACTPMID:42455536 | DOI:10.1001/jamacardio.2026.2059
Drugs Aging. 2026 Jul 15. doi: 10.1007/s40266-026-01319-4. Online ahead of print.ABSTRACTBACKGROUND: Data on age-specific outcomes in patients with atrial fibrillation (AF) treated with edoxaban in real-world settings are limited; this prespecified analysis of the ETAF-TR study aimed to investigate
