Neural Regen Res. 2025 Dec 30. doi: 10.4103/NRR.NRR-D-25-00988. Online ahead of print.ABSTRACTAtaxia-telangiectasia is a rare neurodegenerative disease with a complex phenotype, which has recently been associated with alterations in metabolism, inadequate responses to oxidative stress and inflammati
J Am Heart Assoc. 2025 Dec 30:e043643. doi: 10.1161/JAHA.125.043643. Online ahead of print.ABSTRACTBACKGROUND: The subendocardial viability ratio (SEVR) reflects myocardial perfusion relative to workload. This study explored the association of SEVR with mortality and subclinical target organ damage
J Am Heart Assoc. 2025 Dec 30:e044438. doi: 10.1161/JAHA.125.044438. Online ahead of print.ABSTRACTBACKGROUND: Plasma biomarkers may aid Alzheimer disease (AD) diagnosis and prognosis. Cardiovascular risk contributes to cognitive decline in AD, but whether it modifies the relationship between plasma
J Am Heart Assoc. 2025 Dec 30:e044826. doi: 10.1161/JAHA.125.044826. Online ahead of print.ABSTRACTBACKGROUND: Previous studies have identified a link between cancer and cardiovascular disease; however, the underlying genetic and proteomic mechanisms remain unclear. Therefore, this study aimed to in
J Am Heart Assoc. 2025 Dec 30:e039828. doi: 10.1161/JAHA.124.039828. Online ahead of print.ABSTRACTBACKGROUND: Black Americans have greater coronary heart disease (CHD) burden than White Americans, disparities that are largely socially determined. Discriminatory societal practices that systematicall
J Am Heart Assoc. 2025 Dec 30:e039855. doi: 10.1161/JAHA.124.039855. Online ahead of print.ABSTRACTBACKGROUND: Atherosclerosis is considered as a major contributor for cardiovascular disease with high morbidity and mortality globally. However, the cross-talk between efferocytosis and inflammation in
J Am Heart Assoc. 2025 Dec 30:e042387. doi: 10.1161/JAHA.125.042387. Online ahead of print.ABSTRACTBACKGROUND: Hematoma expansion (HE) is a significant risk factor for poor prognosis in patients with intracerebral hemorrhage (ICH). Accurately predicting HE is crucial for determining optimal treatmen
J Am Heart Assoc. 2025 Dec 30:e045433. doi: 10.1161/JAHA.125.045433. Online ahead of print.ABSTRACTBACKGROUND: Data on associations between genetic predisposition to high blood pressure (BP) and hypertension and its complications in non-European populations are limited. The current study investigate
J Intern Med. 2025 Dec 30. doi: 10.1111/joim.70055. Online ahead of print.ABSTRACTPrimary aldosteronism (PA) is a common cause of hypertension. Compared to patients with essential hypertension, untreated PA is associated with a two- to fourfold greater risk of cardiovascular disease, renal failure,
Arterioscler Thromb Vasc Biol. 2025 Dec 30. doi: 10.1161/ATVBAHA.125.323888. Online ahead of print.ABSTRACTBACKGROUND: Atherosclerosis is a leading cause of cardiovascular diseases, and microRNA-26b (miR-26b) has emerged as a significant regulator in its development. This study investigates the role
Arterioscler Thromb Vasc Biol. 2025 Dec 30. doi: 10.1161/ATVBAHA.125.322880. Online ahead of print.ABSTRACTAbout 10% to 15% of the adult population reports frequent, chronic insomnia symptoms of difficulty initiating or maintaining sleep associated with daytime impairment (ie, insomnia disorder). An
Folia Med (Plovdiv). 2025 Nov 28;67(6). doi: 10.3897/folmed.67.e153542.ABSTRACTHeart failure (HF) poses a major global health burden due to its high prevalence, complexity, and poor prognosis. Although biomarkers such as B-type natriuretic peptides (BNP, NT-proBNP) are widely used for diagnosis and
Int J Cardiol Heart Vasc. 2025 Nov 20;61:101836. doi: 10.1016/j.ijcha.2025.101836. eCollection 2025 Dec.ABSTRACTFatty acid-binding proteins (FABPs) are intracellular lipid-binding proteins that significantly contribute to the transport and metabolism of long-chain fatty acids and other hydrophobic l
iScience. 2025 Nov 19;28(12):114129. doi: 10.1016/j.isci.2025.114129. eCollection 2025 Dec 19.ABSTRACTLung cancer (LC) frequently coexists with cardiometabolic diseases (CMDs), complicating clinical management, but their shared genetic architecture remains largely unknown. Here, we analyzed genome-w
iScience. 2025 Nov 25;28(12):114213. doi: 10.1016/j.isci.2025.114213. eCollection 2025 Dec 19.ABSTRACTSignificant advances have been made in the field of structural heart disease (SHD), yet guideline characteristics and evolution across regions remain uncertain. This study aims to analyze the distri
Int J Gen Med. 2025 Dec 23;18:7755-7774. doi: 10.2147/IJGM.S567837. eCollection 2025.ABSTRACTPURPOSE: Heart rate recovery, measured during exercise testing, is an important marker of cardiovascular function. The Heart Rate Recovery Index, a recently proposed parameter derived from heart rate recover
Clin Cosmet Investig Dent. 2025 Dec 24;17:661-680. doi: 10.2147/CCIDE.S560013. eCollection 2025.ABSTRACTAIM: Periodontitis, a highly prevalent chronic inflammatory disease, progressively destroys tooth-supporting tissues, ultimately leading to tooth loss, and significantly increases systemic risks s
Fundam Res. 2025 Jun 30;5(6):2993-3000. doi: 10.1016/j.fmre.2025.06.012. eCollection 2025 Nov.ABSTRACTApproaches to enhance adeno-associated virus (AAV)-based cardiac gene transfer are the key to successful cardiac gene therapy, but factors influencing AAV transduction remain poorly investigated. Th
J Multidiscip Healthc. 2025 Dec 24;18:8209-8223. doi: 10.2147/JMDH.S553225. eCollection 2025.ABSTRACTOBJECTIVE: To analyze the current status, research hotspots, and trends in the application of artificial intelligence (AI) in cardiovascular disease (CVD) using bibliometric methods, providing a refe
J Multidiscip Healthc. 2025 Dec 23;18:8185-8196. doi: 10.2147/JMDH.S560641. eCollection 2025.ABSTRACTOBJECTIVE: Heart rate recovery (HRR) is a validated prognostic marker in cardiovascular disease (CVD). This study evaluated and compared the effects of 4-week high-intensity interval training (HIIT)
Cureus. 2025 Nov 27;17(11):e97927. doi: 10.7759/cureus.97927. eCollection 2025 Nov.ABSTRACTBackground Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease and is closely linked to metabolic risk factors that also predispose to ischemic heart disease (IHD). Evaluating th
Cureus. 2025 Nov 27;17(11):e97972. doi: 10.7759/cureus.97972. eCollection 2025 Nov.ABSTRACTBACKGROUND: Accurate estimation of left ventricular ejection fraction (LVEF) is vital in cardiology practice for diagnostic, prognostic, and management decisions. The biplane Simpson method is the standard but
Cureus. 2025 Nov 27;17(11):e97908. doi: 10.7759/cureus.97908. eCollection 2025 Nov.ABSTRACTKlebsiella aerogenes is a Gram-negative bacterium commonly associated with urinary tract infections (UTIs); however, it can occasionally cause bloodstream infections and, rarely, infective endocarditis (IE). S
Vasc Health Risk Manag. 2025 Dec 23;21:1121-1130. doi: 10.2147/VHRM.S559346. eCollection 2025.ABSTRACTBACKGROUND: Coronary artery disease (CAD) is a leading global health concern, with inflammation playing a pivotal role in its pathogenesis. The high-sensitivity C-reactive protein/albumin ratio (CAR
