JMIR Res Protoc. 2026 May 25;15:e83574. doi: 10.2196/83574.ABSTRACTBACKGROUND: Cardiovascular disease (CVD) is the leading cause of death in women. Risk factors can be compounded by hormonal changes, especially during the menopause transition. Positive health promotion through a behavioral change st
Eur J Heart Fail. 2026 May 25:xuag181. doi: 10.1093/ejhf/xuag181. Online ahead of print.ABSTRACTBACKGROUND: Arrhythmia-induced cardiomyopathy develops unpredictably in a subset of patients with atrial fibrillation, with marked interindividual variability in severity and recurrence risk. Whether gene
J Vis Exp. 2026 May 5;(231). doi: 10.3791/69165.ABSTRACTTo investigate the prognosis of patients with acute-phase cerebral infarction treated with butylphthalide based on cytochrome P450 2C19 (CYP2C19) genotype. A total of 175 patients with acute cerebral infarction treated with butylphthalide at ou
J Vis Exp. 2026 May 5;(231). doi: 10.3791/70664.ABSTRACTRight heart failure (RHF) is a significant cause of morbidity and mortality from pulmonary hypertension (PH). To better understand the pathophysiology and implications of exercise-induced stress, we implemented an exercise regimen to further ch
J Vis Exp. 2026 May 8;(231). doi: 10.3791/70141.ABSTRACTIntracerebral hemorrhage (ICH) is a severe form of stroke associated with high mortality and long-term neurological disability. Conventional surgical evacuation through craniotomy carries substantial risks, particularly for deep-seated hematoma
J Vis Exp. 2026 May 8;(231). doi: 10.3791/70481.ABSTRACTDiabetes is a major independent risk factor for ischemic stroke, exacerbating stroke severity and worsening patient outcomes. Traditional models of stroke, using healthy animals, fail to replicate the complex pathophysiology of diabetes, thereb
J Vis Exp. 2026 May 8;(231). doi: 10.3791/69871.ABSTRACTHypertension is considered a major global health threat, which can lead to severe complications, including vascular remodeling, heart failure, myocardial infarction, and end-stage renal disease. Syrian golden hamsters, a model with naturally e
Cerebrovasc Dis. 2026 May 25:1-13. doi: 10.1159/000552671. Online ahead of print.ABSTRACTINTRODUCTION: The benefits of long-term blood pressure (BP) lowering for the prevention of recurrent stroke and other serious cardiovascular (CV) events in patients who suffer an acute spontaneous intracerebral
J Vis Exp. 2026 May 8;(231). doi: 10.3791/70620.ABSTRACTBronchopulmonary dysplasia with pulmonary hypertension (BPD-PH) is a devastating complication of preterm birth that is associated with increased morbidity and mortality. Preterm birth disrupts normal lung and vascular development, and postnatal
Eur Stroke J. 2026 May 6;11(5):aakag048. doi: 10.1093/esj/aakag048.ABSTRACTINTRODUCTION: Procedure time (PT) during endovascular thrombectomy (EVT) may be associated with clinical outcomes in acute ischaemic stroke (AIS). We evaluated the association between PT and clinical outcomes using a large po
Crit Care Explor. 2026 May 25;8(6):e1418. doi: 10.1097/CCE.0000000000001418. eCollection 2026 Jun 1.ABSTRACTIMPORTANCE: Pediatric cerebral venous sinus thrombosis (CVST) is being increasingly recognized and can pose substantial risks of morbidity and mortality. Data on the epidemiology, management,
Heart Fail Rev. 2026 May 25;31(1):67. doi: 10.1007/s10741-026-10639-x.ABSTRACTCongestion is the main driver of heart failure (HF) recurrence and its relief remains the primary therapeutic target during acute management. In most studies achievement of decongestion is evaluated by clinical examination
Purinergic Signal. 2026 May 25;22(3):52. doi: 10.1007/s11302-026-10164-4.ABSTRACTMyocardial ischemia (MI) often leads to sympathetic overexcitation, though the underlying mechanisms are not fully understood. This work was to elucidate the role of P2Y6 receptors in the superior cervical ganglion (SCG
Rheumatol Int. 2026 May 25;46(6):110. doi: 10.1007/s00296-026-06127-y.ABSTRACTSystemic sclerosis (SSc) is a complex autoimmune disease characterized by immune dysregulation, vasculopathy, and progressive fibrosis. Cardiovascular involvement represents a leading cause of mortality, yet remains underr
Pediatr Cardiol. 2026 May 25. doi: 10.1007/s00246-026-04312-1. Online ahead of print.ABSTRACTThe optimal right ventricular outflow tract (RVOT) conduit in the Ross procedure remains controversial. This study addresses outcomes of decellularized (DH) and cryopreserved homografts (CH) for RVOT reconst
Pediatr Cardiol. 2026 May 25. doi: 10.1007/s00246-026-04310-3. Online ahead of print.ABSTRACTTo evaluate whether transcatheter patent foramen ovale (PFO) closure is associated with higher rates of complete migraine remission in children with migraine and a concomitant right-to-left shunt. We conduct
Curr Obes Rep. 2026 May 25;15(1):41. doi: 10.1007/s13679-026-00719-2.ABSTRACTOBJECTIVE: The aim of this review is to describe and reflect on the methodology of the studies that estimate the attributable mortality (AM) to excess weight. The purpose was to provide a methodological framework and serve
Heart Fail Rev. 2026 May 25;31(1):66. doi: 10.1007/s10741-026-10638-y.ABSTRACTSudden cardiac death (SCD) remains a major cause of mortality among adults with congenital heart disease (ACHD). Risk stratification for malignant ventricular arrhythmias in this population is challenging because of the he
Discov Oncol. 2026 May 25. doi: 10.1007/s12672-026-05266-9. Online ahead of print.ABSTRACTAngiogenesis is a fundamental process in cancer progression, but computational prioritization of angiogenesis-associated genes often relies on predefined gene sets or canonical signaling pathways, limiting the
Biol Trace Elem Res. 2026 May 25. doi: 10.1007/s12011-026-05163-w. Online ahead of print.ABSTRACTOxidative stress and mechanobiological signaling are increasingly recognized as interconnected determinants of cellular and systemic homeostasis. Reactive oxygen species (ROS), traditionally associated w
Eur Heart J. 2026 May 25:ehag399. doi: 10.1093/eurheartj/ehag399. Online ahead of print.ABSTRACTBACKGROUND AND AIMS: There is interest in developing lipoprotein(a) [Lp(a)] lowering therapies. Cholesteryl ester transfer protein inhibitors lower Lp(a), however the effects of the selective inhibitor ob
Adv Sci (Weinh). 2026 May 25:e24231. doi: 10.1002/advs.202524231. Online ahead of print.ABSTRACTExtracellular vesicles (EVs) have emerged as versatile biological carriers capable of transporting diverse therapeutic cargos. Their endogenous biogenesis pathways provide unique opportunities to regulate
Eur Heart J. 2026 May 25:ehag348. doi: 10.1093/eurheartj/ehag348. Online ahead of print.ABSTRACTBACKGROUND AND AIMS: In patients with myocardial infarction (MI), no heart failure, and left ventricular ejection fraction (LVEF) ≥ 40%, the combined BETAMI-DANBLOCK trial showed that beta-blockers reduce
No abstractCirculation. 2026 May 25. doi: 10.1161/CIRCULATIONAHA.126.081436. Online ahead of print.NO ABSTRACTPMID:42183771 | DOI:10.1161/CIRCULATIONAHA.126.081436
