The effects of oral cannabidiol supplementation on blood pressure in adults: a systematic review of randomised controlled trials

J Cannabis Res. 2026 Jun 19. doi: 10.1186/s42238-026-00463-3. Online ahead of print.ABSTRACTBACKGROUND: Hypertension is a leading risk factor for cardiovascular disease, particularly in ageing populations. While pharmacological interventions are common, issues with long-term adherence and side effec

A Albert Roberts

Inverse association between body mass index and abdominal aortic calcification based on NHANES

J Cardiothorac Surg. 2026 Jun 19. doi: 10.1186/s13019-026-04416-y. Online ahead of print.ABSTRACTBACKGROUND: The increasing prevalence of obesity worldwide has led to conflicting research on its cardiovascular effects. Although obesity is an established risk factor for cardiovascular disease (CVD),

Y Yuxing Wang

Serum FAP+ exosome-based flow cytometric detection: potential utility in early diagnosis, disease progression assessment, and surgical response monitoring of lung adenocarcinoma

J Nanobiotechnology. 2026 Jun 19. doi: 10.1186/s12951-026-04695-6. Online ahead of print.ABSTRACTBACKGROUND: Lung adenocarcinoma (LUAD) remains a leading cause of cancer-related mortality, and currently available serum biomarkers have limited sensitivity and specificity for early diagnosis. We inves

M Ming Liu

Serum uric acid is associated with advanced stages in patients with cardiovascular-kidney-metabolic syndrome

J Cardiothorac Surg. 2026 Jun 19. doi: 10.1186/s13019-026-04437-7. Online ahead of print.ABSTRACTBACKGROUND: In 2023, the American Heart Association introduced the cardiovascular-kidney-metabolic (CKM) syndrome to comprehensively assess multimorbidity involving obesity, diabetes, chronic kidney dise

D Dingyuan Tu

Longitudinal variability of lipoprotein(a) in youth-onset type 1 diabetes: implications for cardiovascular risk stratification

Cardiovasc Diabetol. 2026 Jun 19. doi: 10.1186/s12933-026-03252-7. Online ahead of print.ABSTRACTBACKGROUND: Lipoprotein(a) [Lp(a)] is a genetically determined and independent cardiovascular risk factor, traditionally considered stable across the lifespan, supporting a single lifetime measurement st

F Fanny Iafrate-Luterbacher

Impact of OMEGA-3 fatty acid in patients undergoing hemodialysis: a systematic review and meta-analysis

BMC Nephrol. 2026 Jun 19. doi: 10.1186/s12882-026-05140-4. Online ahead of print.ABSTRACTBACKGROUND: Cardiovascular disease is the leading cause of death among patients undergoing hemodialysis, while effective preventive strategies remain limited. Omega-3 polyunsaturated fatty acids (n-3 PUFAs) have

H Hafiz Bilal Ahmed Jilani

Impact of a comprehensive healthy lifestyle and genetic risk on arrhythmia: insights from the UK biobank study

BMC Cardiovasc Disord. 2026 Jun 19. doi: 10.1186/s12872-026-06146-4. Online ahead of print.ABSTRACTBACKGROUND: Arrhythmias such as atrial fibrillation and bradyarrhythmia impose a substantial public health burden. Although genetic predisposition contributes to arrhythmia risk, the extent to which mo

Q Qingmiao Yang

Functional mitral valve regurgitation outcomes by treatment modality: a systematic review and meta-analysis of reconstructed survival data

BMC Cardiovasc Disord. 2026 Jun 19. doi: 10.1186/s12872-026-06106-y. Online ahead of print.ABSTRACTBACKGROUND: Functional mitral regurgitation (FMR) carries poor prognosis, and optimal management remains debated. Mitral Transcatheter Edge-to-Edge Repair (MTEER) is an alternative to surgical repair (

P Parham Dastjerdi

Association of the mitochondrial regulator PGC-1α with diabetes mellitus and myocardial ischemia-reperfusion injury in coronary artery bypass grafting

BMC Cardiovasc Disord. 2026 Jun 19. doi: 10.1186/s12872-026-06151-7. Online ahead of print.ABSTRACTOBJECTIVES: This study aimed to evaluate whether peroxisome proliferator-activated receptor gamma coactivator-1 alpha (PGC-1α) could serve as a marker of myocardial ischemia by examining its associatio

A Ayla Yildiz

Comparative Cardiovascular, Lipid, and Safety Effects of Lipid-Modifying Therapies in Diabetes: An Agent-, Class-, and Dose-Level Network Meta-Analysis

Cardiovasc Drugs Ther. 2026 Jun 20. doi: 10.1007/s10557-026-07885-4. Online ahead of print.ABSTRACTAIMS: Comprehensive and fine-grained evidence of lipid-lowering drugs in patients with diabetes is lacking. This study aims to compare the efficacy and safety of lipid-modifying agents in this populati

X Xudong Zhao

MSCA-TNet based deep learning method for ECG arrhythmia classification

Sci Rep. 2026 Jun 19. doi: 10.1038/s41598-026-58850-y. Online ahead of print.ABSTRACTElectrocardiography (ECG) is a widely adopted modality for monitoring cardiac rate and rhythm and identifying various abnormalities of the cardiac electrical system. Research on ECG preprocessing and intelligent cla

S Songjian Huang

Recent developments and challenges in hypertensive dementia over the past year

Hypertens Res. 2026 Jun 19. doi: 10.1038/s41440-026-02714-5. Online ahead of print.ABSTRACTThe Guidelines for the Management of Elevated Blood Pressure and Hypertension 2025 (JSH2025) were published last year. Additionally, the Prevention of Cognitive Impairment by Hypertension Management (PCIHM) wo

M Masaki Mogi

Biomimetic macrophage membrane-coated nanoparticles for targeted cardioprotection against myocardial ischaemia-reperfusion injury

Sci Rep. 2026 Jun 19. doi: 10.1038/s41598-026-58344-x. Online ahead of print.ABSTRACTMyocardial ischaemia-reperfusion injury (MIRI) exacerbates cardiomyocyte damage through oxidative stress, inflammation, and apoptosis, limiting the efficacy of reperfusion therapies. We developed PB1-Lip@M-CST, a bi

H Hengheng Li

Gut microbiome signatures discriminate deep vein thrombosis through machine learning and metabolic analysis

Sci Rep. 2026 Jun 19. doi: 10.1038/s41598-026-55650-2. Online ahead of print.ABSTRACTDeep vein thrombosis (DVT) remains difficult to distinguish because of its often silent presentation and the limited specificity of current diagnostic tools. We aimed to evaluate whether integrating gut microbiome p

C Chiung-Ray Lu

Cardiovascular disease incidence among aging patients with rheumatoid arthritis: Results from the Canadian Longitudinal Study on Aging (CLSA)

Nutr Metab Cardiovasc Dis. 2026 Jun 12:104845. doi: 10.1016/j.numecd.2026.104845. Online ahead of print.ABSTRACTBACKGROUND AND AIMS: Rheumatoid arthritis (RA) is associated with a higher risk of cardiovascular disease (CVD). This study examined CVD incidence among middle-aged and older Canadians wit

Y Yasaman Hajiesmaeili

Associations between modifiable lifestyle risk factors and abdominal aortic calcification in the UK Biobank Imaging Study

Nutr Metab Cardiovasc Dis. 2026 Jun 9:104843. doi: 10.1016/j.numecd.2026.104843. Online ahead of print.ABSTRACTBACKGROUND AND AIMS: Abdominal aortic calcification (AAC) reflects subclinical atherosclerotic cardiovascular disease (ASCVD), but its lifestyle determinants remain uncertain. We investigat

N Nicola P Bondonno

Systolic blood pressure modifies the association between triglyceride-glucose-waist-to-height ratio and cardiovascular disease: a nationwide cohort study

Nutr Metab Cardiovasc Dis. 2026 Jun 9:104842. doi: 10.1016/j.numecd.2026.104842. Online ahead of print.ABSTRACTBACKGROUND AND AIM: Triglyceride-glucose-waist-to-height ratio (TyG-WHtR) index and blood pressure are independent predictors of cardiovascular disease risk. However, the interaction betwee

J Junfu Chen

Added value of photon-counting CT for triple rule-out imaging: A propensity-matched comparison with energy-integrating CT

J Cardiovasc Comput Tomogr. 2026 Jun 19:S1934-5925(26)00402-8. doi: 10.1016/j.jcct.2026.06.006. Online ahead of print.ABSTRACTPURPOSE: To compare the technical performance of photon-counting detector (PCD)-CT and energy-integrating detector (EID)-CT in triple rule-out (TRO) imaging.METHODS: In this

S Sardi Hyska

Interpretable machine learning and incremental prognostic model for all-cause and cardiovascular mortality in obesity with MASLD population: Comorbidity insights from triglyceride-glucose and its obesity-related derivatives

Obes Res Clin Pract. 2026 Jun 19:S1871-403X(26)00065-7. doi: 10.1016/j.orcp.2026.06.005. Online ahead of print.ABSTRACTOBJECTIVE: To investigate comorbid correlation and prognostic value of triglyceride-glucose (TyG) and its obesity-related derivatives for all-cause and cardiovascular mortality in t

L Limin Nie

APOE4 negates the effects of ovarian hormones on cerebrovascular endothelial and mitochondrial function

J Physiol. 2026 Jun 19. doi: 10.1113/JP290852. Online ahead of print.ABSTRACTThe APOEε4 allele and oestrogen deficiency independently predispose females to an increased risk of vascular and metabolic impairments, but their cerebrovascular effects are less understood. The purpose of this study was to

M Mackenzie N Kehmeier

Adolescent perspectives on the barriers and facilitators of engagement in healthy lifestyle behaviours: a focus group study from the European SEEDS project

BMJ Open. 2026 Jun 19;16(6):e115125. doi: 10.1136/bmjopen-2025-115125.ABSTRACTBACKGROUND: Adolescent obesity is increasing worldwide, and a minority of adolescents are meeting recommended physical activity (PA) and dietary guidelines, particularly among adolescents from low socioeconomic areas. Ther

A Annemieke Wargers

Interventions for Silent Brain Infarction and Perioperative Neurocognitive Disorders in Cardiovascular Surgery (INSPIRE): study protocol for a multicentre randomised controlled trial

BMJ Open. 2026 Jun 19;16(6):e116246. doi: 10.1136/bmjopen-2026-116246.ABSTRACTINTRODUCTION: The incidence of silent brain infarction (SBI) and perioperative neurocognitive disorders (PND) is higher in cardiac surgery. However, standard preventive strategies remain unknown due to limited evidence.MET

L Lu Wang

Structural, biophysical and cellular assessment of filamin C M82K: A test case for VUS interpretation in cardiomyopathy

J Mol Cell Cardiol. 2026 Jun 19:S0022-2828(26)00093-3. doi: 10.1016/j.yjmcc.2026.06.009. Online ahead of print.ABSTRACTFilamin C (FLNC) is a key Z-disc protein that anchors actin filaments to membrane-bound complexes and is essential for sarcomeric stability and mechanotransduction. Genetic variants

M Maya Noureddine

Circulating Extracellular Vesicles as Systemic Mediators of Cardiac Aging: Mechanisms, Biomarkers, and Therapeutic Perspectives

Ageing Res Rev. 2026 Jun 19:103212. doi: 10.1016/j.arr.2026.103212. Online ahead of print.ABSTRACTCardiac aging is a fundamental contributor to heart failure, arrhythmias, impaired stress tolerance, and reduced cardiovascular resilience in the elderly. While intrinsic myocardial aging has been widel

C Chan Zhang