Eur J Heart Fail. 2026 Oct 14:xuag322. doi: 10.1093/ejhf/xuag322. Online ahead of print.ABSTRACTBACKGROUND: Lower extremity compression therapy has been proposed as an adjunct to mitigate diuretic resistance during acute decompensation of heart failure (ADHF). We evaluated the effect of lower leg co
Clin Exp Dermatol. 2026 Oct 14:llag447. doi: 10.1093/ced/llag447. Online ahead of print.ABSTRACTBACKGROUND: Due to the limited laser penetration depth, reflectance confocal microscopy (RCM) application in the study of thick cutaneous lesions has been limited so far.OBJECTIVES: To describe clinical,
Clin Appl Thromb Hemost. 2026 Jan-Dec;32:10760296261497036. doi: 10.1177/10760296261497036. Epub 2026 Oct 14.ABSTRACTBackgroundThe neutrophil-to-lymphocyte ratio (NLR) and atherogenic index of plasma (AIP) have been associated with coronary artery disease (CAD). We investigated their associations wi
A A Pract. 2026 Oct 14;20(10):e02309. doi: 10.1213/XAA.0000000000002309. eCollection 2026 Oct 1.ABSTRACTA 34-year-old woman, 2 days post-partum, was admitted to the intensive care unit (ICU) for management of hypertensive crisis and respiratory failure. An 18-cm left adrenal mass was found on comput
Online J Public Health Inform. 2026 Jul 19. doi: 10.2196/90677. Online ahead of print.ABSTRACTBACKGROUND: Steatotic liver disease (SLD) is highly prevalent and noninvasive identification of patients with significant fibrosis remains a clinical challenge.OBJECTIVE: We conducted an exploratory evaluat
J Clin Invest. 2026 Oct 13:e201899. doi: 10.1172/JCI201899. Online ahead of print.ABSTRACTAs rates of type 2 diabetes mellitus (T2DM) have risen, comorbidities of T2DM and cardiovascular disease (CVD) have similarly increased. The adoption of sodium-glucose cotransporter (SGLT) 2 inhibitors as a tre
Salud Publica Mex. 2026 Oct 10;68(5 (sept-oct)):552-560. doi: 10.21149/18209.ABSTRACTEn México, las enfermedades cardiovasculares constituyen la principal causa de mortalidad de acuerdo con los datos del Inegi, registrándose anualmente cerca de 200 000 defunciones; la cardiopatía isquémica predomina
J Invasive Cardiol. 2026 Oct 14. doi: 10.25270/jic/26.00260. Online ahead of print.ABSTRACTOBJECTIVES: To compare characteristics and in-hospital outcomes of dialysis vs non-dialysis patients undergoing chronic total occlusion percutaneous coronary intervention (CTO PCI).METHODS: The authors analyze
Sci Transl Med. 2026 Oct 14;18(871):eady4852. doi: 10.1126/scitranslmed.ady4852. Epub 2026 Oct 14.ABSTRACTThe incidence and mortality of high-grade endometrial cancers are increasing, and heterozygous hotspot mutations in PPP2R1A are drivers of the most aggressive forms of uterine cancer. PPP2R1A en
Sci Transl Med. 2026 Oct 14;18(871):eadz4815. doi: 10.1126/scitranslmed.adz4815. Epub 2026 Oct 14.ABSTRACTAging is characterized by progressive functional decline, yet metabolomic signatures across the human life span remain incompletely defined. Here, we profiled plasma metabolomes from 18,476 part
Wounds. 2026 Sep;38(9):224-236. doi: 10.25270/wnds/25122.ABSTRACTBACKGROUND: Chronic wounds present a significant health concern due to their prolonged healing time, risk of severe complications, and the burden they place on patients, health care providers, and the health system.OBJECTIVE: To prospe
Wounds. 2026 Sep;38(9):237-246. doi: 10.25270/wnds/25098.ABSTRACTBACKGROUND: Venous leg ulcers (VLUs) frequently exhibit prolonged healing times, particularly in the presence of lower extremity lymphedema. One approach to managing VLU is to combine traditional wound care with lymphedema therapy (LT)
PLoS One. 2026 Oct 14;21(10):e0358696. doi: 10.1371/journal.pone.0358696. eCollection 2026.ABSTRACTHypertension and aging are associated with endothelial dysfunction in skeletal muscle, potentially compromising exercise capacity. Although high-intensity interval training (HIIT) has been proposed as
PLoS One. 2026 Oct 14;21(10):e0357182. doi: 10.1371/journal.pone.0357182. eCollection 2026.ABSTRACTBACKGROUND: Asian Indians face an increased burden of cardiometabolic diseases, yet the interplay between genetic predisposition and diet quality in this population remains underexplored. This study ai
PLoS One. 2026 Oct 14;21(10):e0360695. doi: 10.1371/journal.pone.0360695. eCollection 2026.ABSTRACTOBJECTIVE: To explore the effects and related mechanisms of a β-blocker combined with a 5-hydroxytryptamine 1A receptor (5-HT1AR) agonist on MI injuries in rats.METHODS: TTC/Evans blue, H&E, Masson, an
Am J Case Rep. 2026 Oct 14;27:e954629. doi: 10.12659/AJCR.954629.ABSTRACTBACKGROUND Peritoneal loose bodies (PLBs) are rare, benign intraperitoneal entities usually discovered incidentally during abdominal surgery or imaging. Their occurrence during urologic laparoscopy appears to be infrequently re
Am J Nephrol. 2026 Oct 14:1. doi: 10.1159/ajn/ablag018. Online ahead of print.ABSTRACTINTRODUCTION: Chronic kidney disease (CKD) is associated with a markedly increased cardiovascular (CV) risk. The disruption of the αKlotho-Fibroblast Growth Factor 23 (FGF23)-FGF receptors (FGFR) axis has been impl
Clin Exp Rheumatol. 2026 Oct 2. doi: 10.55563/clinexprheumatol/hlgq7q. Online ahead of print.ABSTRACTOBJECTIVES: Cardiac involvement in eosinophilic granulomatosis with polyangiitis (EGPA) occurs in approximately 20-40% of patients and has been shown to be a major predictor of mortality. Cardiac mag
Clin Exp Rheumatol. 2026 Oct 7. doi: 10.55563/clinexprheumatol/fhrzy8. Online ahead of print.ABSTRACTOBJECTIVES: Behçet's disease (BD) is a chronic, systemic inflammatory disorder. Despite the presence of chronic inflammation in BD, a clear increase in atherosclerotic cardiovascular mortality has no
Clin Exp Rheumatol. 2026 Oct 7. doi: 10.55563/clinexprheumatol/ctftt6. Online ahead of print.ABSTRACTOBJECTIVES: To evaluate the incidence, time to aortic aneurysm (AA) diagnosis, and factors associated with AA development in patients admitted with giant cell arteritis (GCA).METHODS: We conducted a
World J Pediatr Congenit Heart Surg. 2026 Oct 14:21501351261491199. doi: 10.1177/21501351261491199. Online ahead of print.ABSTRACTThe Fontan operation represents the third stage of single-ventricle palliation and requires optimal cardiovascular and pulmonary conditions to achieve success. We report
J Alzheimers Dis. 2026 Oct 14:13872877261498381. doi: 10.1177/13872877261498381. Online ahead of print.ABSTRACTBackgroundSeveral Alzheimer's disease (AD) clinical trials currently focus on drug repurposing. Machine learning (ML)-based pharmacoepidemiological approaches may help identify candidate dr
Adv Sci (Weinh). 2026 Oct 14:e78230. doi: 10.1002/advs.78230. Online ahead of print.ABSTRACTCuproptosis, a novel anti-cancer mechanism, holds significant potential for triggering sequential immunotherapy to enhance anti-cancer efficacy. However, this cascade effect is often limited by copper efflux
JMIR Cardio. 2026 Oct 14;10:e88399. doi: 10.2196/88399.ABSTRACTBACKGROUND: Occlusion myocardial infarction (OMI) on the electrocardiogram (ECG) can present as ST-elevation myocardial infarction (STEMI), non-STEMI, ST depression, or other patterns (eg, de Winter T waves and hyperacute T waves), posin
