Persistent Attenuation of Lymphocyte Subsets After Mass SARS-CoV-2 Infection

Int J Infect Dis. 2025 Dec 5:108287. doi: 10.1016/j.ijid.2025.108287. Online ahead of print.ABSTRACTOBJECTIVES: Growing evidence suggests that lymphocyte subsets are declined in COVID-19 patients, but it is unclear if these alterations persist after widespread exposure to SARS-CoV-2 or how long they

Z Zhengqi Jiang

Cysteine Cathepsins and Drug Discovery: Knowns and Unknowns

Biochemistry (Mosc). 2025 Nov;90(11):1757-1763. doi: 10.1134/S0006297925602205.ABSTRACTCysteine cathepsins are a group of closely related proteolytic enzymes active at low pH. The most well-studied function of these enzymes is protein degradation within lysosomes. However, accumulating evidence sugg

A Andrey A Zamyatnin