The Dual Role of Uric Acid: Pathological Implications Across Chronic Diseases and Current Approaches to Hyperuricemia Management

Discoveries (Craiova). 2026 Jun 30;14(2):e231. doi: 10.15190/d.2026.10. eCollection 2026 Apr-Jun.ABSTRACTUric acid is the end product of purine metabolism and plays a dichotomous role in the human body. On one hand, it exerts antioxidant and neuroprotective effects; on the other hand, chronic hyperu

A Aiza Zehra

Low Vitamin D Status and Post-Stroke Depression, Falls, and Functional Recovery in Older Adults with Nonvalvular Atrial Fibrillation-Associated Ischemic Stroke

Clin Interv Aging. 2026 Jul 28;21:607805. doi: 10.2147/CIA.S607805. eCollection 2026.ABSTRACTBACKGROUND: Older adults with atrial fibrillation (AF)-associated acute ischemic stroke are prone to disability, depressive symptoms, and falls; the prognostic value of vitamin D status is uncertain.METHODS:

L Li Li

Acute upper limb ischemia: a complication of acute coronary syndrome (a case report)

Pan Afr Med J. 2026 May 11;54:7. doi: 10.11604/pamj.2026.54.7.50791. eCollection 2026.ABSTRACTWe here report the case of a 30-year-old woman presenting with acute coronary syndrome complicated by acute ischemia of the left upper limb. She underwent Fogarty thrombectomy via humeral approach, with unc

D Dialtabé Ibrahima Guessé Ba

Integrating AI-Driven Diagnostics in Arrhythmia Care to Enhance Patient Outcomes: A Narrative Review

Cureus. 2026 Jul 22;18(7):e113138. doi: 10.7759/cureus.113138. eCollection 2026 Jul.ABSTRACTInternational morbidity and mortality are led by cardiovascular disease, specifically arrhythmias. The integration of artificial intelligence (AI) can promote earlier identification and, therefore, provide pe

M Mustafa Abrar Zaman

Sociodemographic differences in long-term survival among children and young people with life-limiting conditions: A 10-year cohort analysis using national health insurance data

Palliat Care Soc Pract. 2026 Jul 31;20:26323524261474071. doi: 10.1177/26323524261474071. eCollection 2026.ABSTRACTBACKGROUND: Children and young people (CYP) with life-limiting conditions (LLCs) comprise a clinically heterogeneous population with diverse disease trajectories and survival patterns.

S Seonhwa Lee

Post-diagnostic smoking cessation and heart-disease mortality among adults smoking at cardiopulmonary disease diagnosis: An NHANES linked-mortality analysis

Tob Induc Dis. 2026 Jul 31;24. doi: 10.18332/tid/226287. eCollection 2026.ABSTRACTINTRODUCTION: Population-based analyses usually classify smoking status at survey enrollment, which combines people who quit before disease recognition with those who continued smoking through diagnosis and quit afterw

D Dongdong Xu

Atorvastatin-Associated Severe Bradyarrhythmia Following Multiorgan Dysfunction: A Case Report

Clin Case Rep. 2026 Jul 31;14(8):e73270. doi: 10.1002/ccr3.73270. eCollection 2026 Aug.ABSTRACTStatins are the primary treatment for hypercholesterolemia and a cornerstone of atherosclerotic cardiovascular disease prevention. Although generally safe, serious adverse effects may occur in selected pat

X Xiao-Qing Kou

Association between endogenous sex hormones and cardiovascular-kidney-metabolic in US adults: a population-based study

J Diabetes Metab Disord. 2026 Jul 31;25(2):220. doi: 10.1007/s40200-026-02036-w. eCollection 2026 Dec.ABSTRACTOBJECTIVE: The association between endogenous sex hormones and Cardiovascular-kidney-metabolic (CKM) syndrome remains incompletely elucidated.METHODS: We performed a cohort study using clini

R Ruiyan Xie

Risk Factors for Rapid Growth in Undernourished Children: Analysis of Indonesian Family Life Survey

Acta Med Philipp. 2026 Jun 30;60(12):51-57. doi: 10.47895/amp.v60i12.4579. eCollection 2026.ABSTRACTBACKGROUND: Children who suffer from undernutrition would grow rapidly to catch-up-growth after improvement in nutrition intake. However, this rapid growth during early life might have harmful effects

F Firlia Ayu Arini

Development and independent validation of a hypoxemia risk prediction model (HAPPY-12K) for sedated gastrointestinal endoscopy: a multicentre prospective cohort study

EClinicalMedicine. 2026 Jul 23;98:104090. doi: 10.1016/j.eclinm.2026.104090. eCollection 2026 Aug.ABSTRACTBACKGROUND: Hypoxemia is a common and serious complication during sedated gastrointestinal endoscopy for out- and in-patients. Though diagnostic and severity scoring systems of obstructive sleep

N Nana Li

Moving cardio-oncology upstream: Integrating cardiovascular prevention into routine cancer care

No abstractCancer Pathog Ther. 2026 May 25;4(5):335-339. doi: 10.1016/j.cpt.2026.05.002. eCollection 2026 Sep.NO ABSTRACTPMID:42542573 | PMC:PMC13427537 | DOI:10.1016/j.cpt.2026.05.002

M Meiyan Liu

STIM1-mediated Treg instability in HFpEF: a new immunological target emerges?

Cardiovasc Diabetol. 2026 Aug 1;25(1):215. doi: 10.1186/s12933-026-03317-7.ABSTRACTHeart failure with preserved ejection fraction (HFpEF) accounts for nearly half of all heart failure cases and remains a major unmet clinical challenge. Increasing evidence supports the view of HFpEF as a systemic inf

A Anna Planavila

Real-World Analysis of the Association Between Systemic Inflammation, Cardiovascular Events, and Economic Burden Among Patients with Atherosclerotic Cardiovascular Disease and Chronic Kidney Disease

Cardiol Ther. 2026 Aug 1. doi: 10.1007/s40119-026-00459-3. Online ahead of print.ABSTRACTINTRODUCTION: Patients with atherosclerotic cardiovascular disease (ASCVD) and systemic inflammation (SI) or chronic kidney disease (CKD) have poorer outcomes than those without SI or CKD. This study evaluated t

C Chi Nguyen

Is MASLD an independent risk factor for micro- and macrovascular complications of diabetes? A critical reappraisal and future directions

Diabetologia. 2026 Aug 1. doi: 10.1007/s00125-026-06817-z. Online ahead of print.ABSTRACTRecent awareness that metabolic dysfunction-associated steatotic liver disease (MASLD) is a common liver condition in individuals with type 2 diabetes and carries a significant risk of cirrhosis and extrahepatic

S Sabine Kahl

Food selection, cardiorespiratory fitness and the longitudinal association with adiposity among South African school children: the ExAMIN Youth SA study

Eur J Clin Nutr. 2026 Aug 1. doi: 10.1038/s41430-026-01799-y. Online ahead of print.ABSTRACTBACKGROUND: The global pandemic of paediatric obesity, unhealthy diets and physical inactivity are important future health challenges. The purpose of this study was to determine 4-year changes in food selecti

H Herculina Salome Kruger

Health complaints, social impacts, and perceived care effectiveness reported by children with obesity and their parents: a prospective observational study in the Obesity Center CGG cohort

Eur J Pediatr. 2026 Aug 1;185(8):633. doi: 10.1007/s00431-026-07295-6.ABSTRACTObesity is a chronic relapsing disease leading to weight-related health risks for disorders such as cardiovascular diseases, type 2 diabetes, osteoarthritis, and depression. Many studies focus on these weight-related healt

M Maxime M A M van der Velden

Hyperuricemia and prevention of cardiometabolic disease: Unexplored is not unexpected

No abstractEur J Intern Med. 2026 Aug 1:107102. doi: 10.1016/j.ejim.2026.107102. Online ahead of print.NO ABSTRACTPMID:42542405 | DOI:10.1016/j.ejim.2026.107102

C Claudio Borghi

Comparative Performance of SLECRISK and PREVENT for Cardiovascular Risk Prediction in Systemic Lupus Erythematosus

J Rheumatol. 2026 Aug 1:jrheum.2025-1318. doi: 10.3899/jrheum.2025-1318. Online ahead of print.ABSTRACTOBJECTIVE: We compared the predictive performance of SLECRISK, an SLE-specific 10-year CVD risk model, to the new PREVENT (Predicting Risk of cardiovascular disease EVENT) model in our SLE cohort.M

Y Youngmin Kim

Rothia spp.: An unusual cause of infective endocarditis

Enferm Infecc Microbiol Clin (Engl Ed). 2026 Aug-Sep;44(7):503199. doi: 10.1016/j.eimce.2026.503199.ABSTRACTINTRODUCTION: Rothia spp. are commensal organisms involved in serious infections such as infective endocarditis (IE). There is a significant lack of information regarding de clinical course an

J Javier Martínez de Victoria Carazo

Herpes Zoster recurrence and its associated risk factors: A population-based study in primary care in Madrid region (central Spain)

Enferm Infecc Microbiol Clin (Engl Ed). 2026 Aug-Sep;44(7):503185. doi: 10.1016/j.eimce.2026.503185.ABSTRACTBACKGROUND: Although Herpes Zoster (HZ) recurrence rates seem to be increasing, there are few studies exploring them in the general population. We aimed to investigate the HZ recurrence rates

L Laura Reques

Immunoglobulin subclass profiles in depression: Insights from a general population study

Prog Neuropsychopharmacol Biol Psychiatry. 2026 Aug 1:111867. doi: 10.1016/j.pnpbp.2026.111867. Online ahead of print.ABSTRACTThe immune system plays a crucial role in defending the body against harmful invaders, with immunoglobulins being key players in pathogen recognition and neutralization. Immu

S Sandra Van der Auwera

Microspheres in myocardial infarction therapy

Int J Pharm. 2026 Aug 1:127262. doi: 10.1016/j.ijpharm.2026.127262. Online ahead of print.ABSTRACTMyocardial infarction (MI) remains a leading cause of heart failure. Although contemporary interventions improve early survival, they fail to promote cardiac repair or prevent long-term adverse remodeli

T Tailuo Liu

The C-reactive protein-triglyceride-glucose index and its obesity-derived indicators predict cardio-renal-metabolic multimorbidity: evidence from the UK biobank and CHARLS

Diabetes Res Clin Pract. 2026 Aug 1:113475. doi: 10.1016/j.diabres.2026.113475. Online ahead of print.ABSTRACTBACKGROUND: Cardio-renal-metabolic multimorbidity is defined as the coexistence of cardiovascular disease, type 2 diabetes, and chronic kidney disease. We examined the relationships between

Q Qiuhan Chen

CSF-1 promotes microglial proliferation and ameliorates ischemic brain injury

Neurochem Int. 2026 Aug 1:106233. doi: 10.1016/j.neuint.2026.106233. Online ahead of print.ABSTRACTMicroglia play a pivotal role in the pathophysiology of ischemic stroke, with substantial microglial demise occurring following cerebral ischemia. This study examined whether colony-stimulating factor

S Shiji Deng