Carotid Artery Stenting Is Now an Evidence-Based Adjunct to Intensive Medical Therapy for Stroke Prevention

Neurology. 2026 Sep 22;107(6):e218441. doi: 10.1212/WNL.0000000000218441. Epub 2026 Sep 3.ABSTRACTThe CREST-2 trial demonstrated that carotid artery stenting combined with intensive medical management (IMM) significantly reduces stroke risk in patients with high-grade asymptomatic carotid stenosis c

J James F Meschia

Evaluation of Disease Severity Using CSF Biomarkers in Patients With Probable Cerebral Amyloid Angiopathy

Neurology. 2026 Sep 22;107(6):e218458. doi: 10.1212/WNL.0000000000218458. Epub 2026 Sep 3.ABSTRACTBACKGROUND AND OBJECTIVES: Cerebral amyloid angiopathy (CAA) is currently diagnosed using MRI-based Boston criteria. However, imaging markers represent downstream consequences of vascular injury and may

Q Quentin Beaufort

Impaired Sinus Rate Behaviour During Ventricular Arrhythmia Is Associated With Adverse Outcomes in ICD Recipients

No abstractEuropace. 2026 Sep 3:euag251. doi: 10.1093/europace/euag251. Online ahead of print.NO ABSTRACTPMID:42691456 | DOI:10.1093/europace/euag251

M Maarten Blondeel

Early and Late TAVI Outcomes in Aortic Stenosis with Transthyretin Cardiac Amyloidosis: A Systematic Review

Eur J Heart Fail. 2026 Sep 3:xuag285. doi: 10.1093/ejhf/xuag285. Online ahead of print.ABSTRACTConcomitant transthyretin cardiac amyloidosis (ATTR-CA) is increasingly recognized among elderly patients with severe aortic stenosis (AS) referred to transcatheter aortic valve implantation (TAVI), yet it

M Martina Giusti

Machine Learning and Molecular Modeling Reveal HDAC6 as a Key Target of Tanshinone IIA in Multiple Myeloma

J Phys Chem B. 2026 Sep 3;130(35):9007-9020. doi: 10.1021/acs.jpcb.6c03788.ABSTRACTMultiple myeloma (MM) is a malignant blood cancer marked by severe bone destruction and immune microenvironment disruption. Yet relapse and drug resistance remain major clinical challenges. Tanshinone IIA (TIIA) exhib

J Jian Gao

The Cardiometabolic Effects of Menopause

Obstet Gynecol. 2026 Sep 4. doi: 10.1097/AOG.0000000000006418. Online ahead of print.ABSTRACTCardiovascular disease (CVD) remains the leading cause of death among women, yet CVD risk is frequently underrecognized during midlife, when the menopause transition is accompanied by significant biological

J Jana Karam

Longitudinal Profiling Reveals Divergent Kidney and Brain Immune Responses during Metabolic Syndrome

Aging Dis. 2026 Aug 11. doi: 10.14336/AD.2026.0557. Online ahead of print.ABSTRACTChronic kidney disease (CKD) and cerebral small vessel disease (cSVD) share major cardiometabolic risk factors, including hypertension, diabetes, and obesity. The immune system may play a key role in kidney-brain inter

L Laura Van der Taelen

Extracellular vesicles from the rostral ventrolateral medulla microenvironment regulate stress-induced hypertension via TNF-α-mediated modulation of neuronal excitability

Clin Exp Hypertens. 2026 Dec 31;48(1):2726549. doi: 10.1080/10641963.2026.2726549. Epub 2026 Sep 3.ABSTRACTOBJECTIVE: Stress-induced hypertension (SIH) is driven by sympathetic overactivity, with the rostral ventrolateral medulla (RVLM) serving as a key regulatory hub. Extracellular vesicles (EVs) m

H Haisheng Liu

Clinical Considerations for the Care of the Tactical Athlete With Cardiovascular Abnormalities: A Scientific Statement From the American College of Cardiology and the American Heart Association

Circulation. 2026 Sep 3. doi: 10.1161/CIR.0000000000001476. Online ahead of print.ABSTRACTAIM: The American College of Cardiology/American Heart Association Scientific Statement, "Clinical Considerations for the Care of the Tactical Athlete With Cardiovascular Abnormalities," was written to provide

E Elizabeth H Dineen

Cardiovascular Disease Risk Assessment in United States Military Service Members

No abstractCirculation. 2026 Sep 3. doi: 10.1161/CIRCULATIONAHA.126.081464. Online ahead of print.NO ABSTRACTPMID:42691138 | DOI:10.1161/CIRCULATIONAHA.126.081464

J John-Henry L Dean

Addressing risk factors for hypertensive disorders in pregnancy: A case study of a quality improvement program in two states in Nigeria

PLoS One. 2026 Sep 3;21(9):e0356879. doi: 10.1371/journal.pone.0356879. eCollection 2026.ABSTRACTHypertensive disorders of pregnancy (HDP) including chronic hypertension, gestational hypertension preeclampsia and eclampsia are a leading cause of maternal and perinatal mortality in Nigeria and global

U Ugo Okoli

Real-World Impact of Remote Patient Management on Care Consumption and Care Time in Heart Failure: Retrospective Cohort Study

JMIR Form Res. 2026 Sep 3;10:e89187. doi: 10.2196/89187.ABSTRACTBACKGROUND: Remote patient management (RPM) is a strategy to track daily health data in patients with heart failure (HF) to enable early detection and treatment of decompensation to prevent hospital readmissions. The implementation of R

W Wessel William Nieuwenhuys

Hyperglycemic stress aggravates diabetic retinopathy and nephropathy by promoting cilium disassembly via a deacetylation- and methylation-mediated regulatory mechanism

PLoS Biol. 2026 Sep 3;24(9):e3003975. doi: 10.1371/journal.pbio.3003975. eCollection 2026 Sep.ABSTRACTPrimary cilia are essential microtubule-based sensory organelles, and their dysfunction has been increasingly linked to metabolic stress. However, the underlying molecular mechanisms remain poorly u

J Jie Ran

EIF1 coordinates transcriptomic and splicing networks associated with cell cycle dysregulation in diabetic retinopathy

PLoS One. 2026 Sep 3;21(9):e0355473. doi: 10.1371/journal.pone.0355473. eCollection 2026.ABSTRACTPURPOSE: EIF1, an RNA-binding protein implicated in multiple diseases, remains poorly characterized in diabetic retinopathy (DR). This study therefore investigated EIF1 expression and function in an in v

N Na Li

Economic drivers and systemic disparities in invasive coronary angiography: Insights from a national claims database

PLoS One. 2026 Sep 3;21(9):e0356496. doi: 10.1371/journal.pone.0356496. eCollection 2026.ABSTRACTBACKGROUND: Despite the prominent economic burden of coronary care, detailed analyses of factors associated with expenditure in developing nations remain sparse.OBJECTIVES: This study aimed to provide su

S Seyed Sahab Aarabi

Ending the single versus multi-bedroom debate: Hybrid rooms meet stroke rehabilitation needs

PLoS One. 2026 Sep 3;21(9):e0356623. doi: 10.1371/journal.pone.0356623. eCollection 2026.ABSTRACTStroke is a leading cause of disability worldwide, and stroke rehabilitation plays a critical role in recovery. Early rehabilitation often occurs in a hospital setting, but the hospital built environment

M Marcus White

A Near-Fatal Leak: Acute Cardiac Tamponade From Contrast Extravasation via a Thrombosed Port-a-Cath

Am J Case Rep. 2026 Sep 3;27:e953197. doi: 10.12659/AJCR.953197.ABSTRACTBACKGROUND Cardiac tamponade caused by intrapericardial contrast extravasation is a rare but life-threatening iatrogenic complication associated with central venous access devices (CVADs) during power injection. CVADs, including

H Hamza Janjua

Diagnostic performance of computed tomography-derived fractional flow reserve in patients with severe aortic stenosis undergoing transcatheter aortic valve implantation: a single-centre feasibility study

Cardiovasc J Afr. 2026 Aug 28;37(3):375-380. doi: 10.5830/CVJA-2026-032. Epub 2026 Aug 28.ABSTRACTOBJECTIVE: Coronary artery disease (CAD) is prevalent in patients with severe aortic stenosis (AS) undergoing transcatheter aortic valve implantation (TAVI). Computed tomography-derived fractional flow

S Soner Aksüyek

Factors associated with prehospital delay in stroke: A multicentre study from eastern India

Indian J Med Res. 2026 Sep;164(3):412-416. doi: 10.25259/IJMR_285_2026.ABSTRACTBackground and objectives Prehospital delay is a significant challenge in stroke management. Our study aims to identify factors associated with prehospital delay in stroke. Methods This cross-sectional study was conducted

A Arpan Dutta

Biohybrid Fused-Cell Carrier for Programmable Therapeutic Modulation of Atherosclerosis

Nano Lett. 2026 Sep 2;26(34):11296-11304. doi: 10.1021/acs.nanolett.6c01968.ABSTRACTCardiovascular disease, driven primarily by atherosclerosis, remains a leading cause of global mortality. Lipid-lowering therapies reduce risk by less than one-third, leaving substantial residual inflammation compoun

G Guanghao Wu

Weekly Journal Scan: In search of a sweet spot for prolonged dual antiplatelet therapy in patients with multivessel coronary artery disease

No abstractEur Heart J. 2026 Sep 3:ehag684. doi: 10.1093/eurheartj/ehag684. Online ahead of print.NO ABSTRACTPMID:42690740 | DOI:10.1093/eurheartj/ehag684

R Rocco Vergallo

From insulin resistance to incretin receptor agonism in the prevention of type 2 diabetes mellitus in obese individuals

Curr Med Res Opin. 2026 Sep 3:1-15. doi: 10.1080/03007995.2026.2727202. Online ahead of print.ABSTRACTType 2 diabetes mellitus (T2DM) represents one of the most significant metabolic challenges of the modern era, with more than 828 million people worldwide living with diabetes. Obesity and insulin r

B Branislava Teofilović

Calcified amorphous tumor in a patient receiving peritoneal dialysis with severe, treatment-refractory hyperphosphatemia

Perit Dial Int. 2026 Sep 3:8968608261479962. doi: 10.1177/08968608261479962. Online ahead of print.ABSTRACTCalcified amorphous tumors (CATs) are rare, non-neoplastic intracardiac masses first described by Reynolds et al. in 1997. Although increasingly reported, their pathogenesis remains poorly unde

P Parth I Kumar

Clinical characteristics of patients with primary antiphospholipid syndrome and "single" antiphospholipid antibody: Retrospective results from the APS ACTION clinical database and repository ("registry")

Lupus. 2026 Sep 3:9612033261479899. doi: 10.1177/09612033261479899. Online ahead of print.ABSTRACTObjectiveWhile triple antiphospholipid antibody (aPL) positivity is associated with a higher risk of thrombosis, the clinical significance of single aPL positivity remains unclear. This study aimed to a

S Silvia Grazietta Foddai