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Cardiovascular disease

Dual Antiglutamate Therapy in Super-Refractory Status Epilepticus After Cardiac Arrest (SUPER-CAT Study)

Neurology. 2026 Oct 27;107(8):e218565. doi: 10.1212/WNL.0000000000218565. Epub 2026 Oct 5.ABSTRACTBACKGROUND AND OBJECTIVES: The SUPER-refractory status epilepticus (SE) after Cardiac Arrest Treatment (SUPER-CAT) study evaluated the efficacy and safety of dual antiglutamate therapy (combined AMPA an

S Simone Beretta

Cardiorenal Syndrome Reimagined: From Hemodynamic Failure to a Multisystem Cardio-Renal-Metabolic-Inflammatory Network in the SGLT2 Era

Cardiol Rev. 2026 Sep 7. doi: 10.1097/CRD.0000000000001445. Online ahead of print.ABSTRACTCardiorenal syndrome (CRS) has traditionally been conceptualized as a hemodynamic disorder characterized by bidirectional dysfunction between the heart and kidneys. However, recent advances have expanded this p

H Hamna Shahid

Aspirin in Primary Prevention: Redefining Patient Selection?

No abstractEur J Prev Cardiol. 2026 Oct 6:zwag519. doi: 10.1093/eurjpc/zwag519. Online ahead of print.NO ABSTRACTPMID:42837614 | DOI:10.1093/eurjpc/zwag519

G Gabriela Silva

Outcomes Across the Lifespan After Preterm Birth: An Overview for Primary Care Clinicians

Pediatr Ann. 2026 Oct;55(10):e406-e411. doi: 10.3928/19382359-20260730-05. Epub 2026 Oct 1.ABSTRACTBirth before 32 weeks' gestation, once associated with early mortality, now is commonly associated with long-term survival. Following discharge from the neonatal intensive care setting, the medical hom

J Jane E Brumbaugh

User Experiences With a Social Robot for Cardiometabolic Risk Assessment in a Community Setting in Uppsala, Sweden: Qualitative Semistructured Interview Study

J Med Internet Res. 2026 Oct 6;28:e87025. doi: 10.2196/87025.ABSTRACTBACKGROUND: Cardiometabolic diseases (CMDs) are a major health concern worldwide, with people living in socioeconomically disadvantaged areas being disproportionately affected. Knowing one's risk status for developing a CMD can hel

S Solveig Dolores Bruchhof

Reproducibility of Published Randomized Controlled Trial Results in Cardiovascular Surgery: Protocol for a Meta-Epidemiological Umbrella Review

JMIR Res Protoc. 2026 Oct 6;15:e93997. doi: 10.2196/93997.ABSTRACTBACKGROUND: Reproducible study findings are those that are shown to be identical or nearly identical when an original study is repeated using similar methods. Findings from many randomized controlled trials (RCTs) in cardiovascular su

A Allen Li

Laboratory methods and quality assurance in the National Longitudinal Study of Adolescent to Adult Health Waves V and VI

J Gerontol B Psychol Sci Soc Sci. 2026 Oct 1;81(Supplement_2):S125-S138. doi: 10.1093/geronb/gbag153.ABSTRACTOBJECTIVES: Gerontological and population health sciences increasingly emphasize life-course, biosocial frameworks linking social environments to biological aging and disease processes, for w

T Timothy B Plante

Phenotypic screening identifies kenpaullone as a prolymphangiogenic compound to improve heart repair following myocardial infarction

Proc Natl Acad Sci U S A. 2026 Oct 13;123(41):e2619427123. doi: 10.1073/pnas.2619427123. Epub 2026 Oct 6.ABSTRACTMyocardial infarction (MI) induces cardiac muscle death and its subsequent replacement by a noncontractile fibrotic scar, which underlies progression to heart failure. Current treatments

C Christophe Ravaud

DNAAF19-RUVBL1/2 complex recruits multiple adaptors to promote dynein arm assembly

Proc Natl Acad Sci U S A. 2026 Oct 13;123(41):e2612755123. doi: 10.1073/pnas.2612755123. Epub 2026 Oct 6.ABSTRACTCilia are microtubule-based organelles essential for sensing, motility, and fluid transport. Motile cilia rely on inner and outer dynein arms, large multiprotein motor complexes, for forc

M Mafalda de Almeida Gomes

Dyssynchrony without dysfunction: Left bundle branch block does not acutely reduce cardiac output

J Physiol. 2026 Oct 6. doi: 10.1113/JP291482. Online ahead of print.ABSTRACTLeft bundle branch block (LBBB) describes a disruption or delay in electrical conduction through the left bundle branch of the His-Purkinje system (HPS). While new-onset LBBB commonly emerges in individuals with a history of

C Carola Kruthoff

Neutrophil-derived oncostatin m contributes to endothelial cell dysfunction during Treponema denticola interaction

PLoS One. 2026 Oct 6;21(10):e0351640. doi: 10.1371/journal.pone.0351640. eCollection 2026.ABSTRACTPeriodontitis (PD) is a common chronic inflammatory condition and a risk factor for cardiovascular diseases (CVD), yet underlying linking mechanisms remain unclear. The cytokine Oncostatin M(OSM) is ele

D Dayron M Leyva Rodriguez

Association between pre-stroke social participation and current physical resilience across frailty levels among middle-aged and older stroke survivors: A cross-sectional study

PLoS One. 2026 Oct 6;21(10):e0359853. doi: 10.1371/journal.pone.0359853. eCollection 2026.ABSTRACTBACKGROUND: Physical resilience and frailty are related but distinct constructs that may shape adaptation after stroke. Evidence concerning whether pre-stroke social participation is associated with phy

Y Yi Zhang

A machine learning-derived aging index for risk stratification and mortality prediction in cardiovascular-kidney-metabolic syndrome: A retrospective cohort study

PLoS Med. 2026 Oct 6;23(10):e1005078. doi: 10.1371/journal.pmed.1005078. eCollection 2026 Oct.ABSTRACTBACKGROUND: The cardiovascular‑kidney‑metabolic (CKM) syndrome shows substantial heterogeneity in progression, yet existing biological age indices are not tailored to CKM pathways. We developed an a

Z Zhengyang Zhu

Pleiotropy and eQTL analysis identify shared genetic architecture of lipid traits in African-ancestry populations

Hum Mol Genet. 2026 Sep 11;35(20):ddag100. doi: 10.1093/hmg/ddag100.ABSTRACTDyslipidemia is a leading modifiable risk factor for cardiovascular disease (CVD), yet the shared genetic architecture of lipid traits remains poorly characterized, particularly in African-ancestry populations who bear a dis

K Knightess Oyibo

Intensive blood-pressure control for the prevention of major cardiovascular events in stroke patients: rationale and design of the OPTIMAL-STROKE trial

Eur Stroke J. 2026 Oct 5;11(10):aakag118. doi: 10.1093/esj/aakag118.ABSTRACTBACKGROUND: In high cardiovascular risk populations without prior stroke, intensive blood pressure (BP) lowering confers greater reductions in cardiovascular events than standard targets. However, optimal BP targets in patie

G Gisele S Silva

Micro- and nanoplastics as emerging cardiovascular risk factors: a new atherogenic player?

Expert Rev Cardiovasc Ther. 2026 Oct 6. doi: 10.1080/14779072.2026.2745395. Online ahead of print.ABSTRACTINTRODUCTION: Microplastics and nanoplastics (MPs/NPs) are emerging environmental contaminants widely detected in food, drinking water, and human biological tissues. As human exposure continues

M Marcelle Barbosa Rosa

Cardiogenic shock with multivessel disease: should we leave non-culprit lesions unattended?

No abstractEuroIntervention. 2026 Oct 5;22(19):e1021-e1022. doi: 10.4244/EIJ-D-26-01084.NO ABSTRACTPMID:42837210 | DOI:10.4244/EIJ-D-26-01084

M Manel Sabaté

Percutaneous coronary intervention using sirolimus-eluting balloons in patients at high bleeding risk: the SELUTION DeNovo HBR substudy

EuroIntervention. 2026 Oct 5;22(19):e1025-e1035. doi: 10.4244/EIJ-D-26-00889.ABSTRACTBACKGROUND: Drug-eluting stents (DES) are the current mainstay of percutaneous coronary intervention (PCI) in high bleeding risk (HBR) patients. However, drug-coated balloons may be an alternative that reduces relia

T Tuomas T Rissanen

Complexity of coronary artery disease in infarct-related cardiogenic shock and multivessel disease: a substudy of the DanGer Shock trial

EuroIntervention. 2026 Oct 5;22(19):e1036-e1047. doi: 10.4244/EIJ-D-26-00460.ABSTRACTBACKGROUND: The prognostic impact of multivessel coronary anatomy and complexity in infarct-related cardiogenic shock (CS) is insufficiently characterised.AIMS: We sought to investigate the prognostic value of basel

J Jasmine M Marquard

Standardised versus visual assessment of device success after percutaneous coronary intervention

EuroIntervention. 2026 Oct 5;22(19):e1048-e1063. doi: 10.4244/EIJ-D-26-00413.ABSTRACTBACKGROUND: The European Association of Percutaneous Cardiovascular Interventions (EAPCI)-endorsed algorithm for defining device success has not yet been prospectively tested against standardised quantitative corona

A Asahi Oshima

Retention risk in European vascular surgery training: workplace conditions outweigh workload

No abstractBr J Surg. 2026 Oct 5;113(10):znag126. doi: 10.1093/bjs/znag126.NO ABSTRACTPMID:42837182 | DOI:10.1093/bjs/znag126

D David Wippel

Comparative Cardiovascular Outcomes of Lanthanum Carbonate and Sevelamer in Dialysis

J Am Soc Nephrol. 2026 Oct 6. doi: 10.1681/ASN.0000001289. Online ahead of print.ABSTRACTBACKGROUND: Hyperphosphatemia is a key component of chronic kidney disease-mineral and bone disorder and is associated with cardiovascular morbidity and mortality in patients receiving dialysis. Non-calcium-base

J Jiao Liu

Early menopause as a female-specific prognostic marker after acute coronary syndrome in women aged 60 years or younger: a real-world multicenter registry analysis

Menopause. 2026 Oct 6. doi: 10.1097/GME.0000000000002896. Online ahead of print.ABSTRACTOBJECTIVE: Early menopause is an established female-specific risk enhancer for incident cardiovascular disease, but its prognostic value after acute coronary syndrome (ACS) remains uncertain. We evaluated whether

K Kristina Marić Bešić

Potential role of CHI3L1 in ischemic stroke - a neuroinflammatory or neuroprotective factor?

Postepy Biochem. 2026 Oct 6;72(3):201-210. doi: 10.18388/wht2rw10.ABSTRACTIschemic stroke is one of the leading causes of disability and death among adults worldwide. It occurs when blood flow to the brain is interrupted. Currently available treatments for patients with ischemic stroke focus solely

A Aleksandra Klachacz