Evidence-based management of kawasaki disease in the emergency department

Pediatr Emerg Med Pract. 2026 Nov;23(11):1-24. Epub 2026 Nov 1.ABSTRACTKawasaki disease is currently the leading cause of acquired heart disease in children in developed countries. Signs and symptoms of Kawasaki disease may mimic other childhood illnesses, making it difficult to diagnose, especially

A Amanda Lee

Oral Versus Injectable Incretin-Based Anti-Obesity Therapies: An Integrated Computational and Evidence-Based Comparison of Orforglipron, Semaglutide, and Tirzepatide

OMICS. 2026 Oct 20:15578100261499499. doi: 10.1177/15578100261499499. Online ahead of print.ABSTRACTIncretin-based agents are transforming obesity pharmacotherapy, and orforglipron, the first oral non-peptide GLP-1 receptor agonist to complete phase 3 testing, invites direct comparison with the inje

L Lorika Sahu

Renin-Aldosterone Activation and Enhanced Urinary Potassium Excretion in Asphyxiated Newborns Treated with Therapeutic Hypothermia: A Prospective Study

Ther Hypothermia Temp Manag. 2026 Dec;16(4):176-182. doi: 10.1177/21537658261416472. Epub 2026 Jan 16.ABSTRACTHypoxic-ischemic encephalopathy (HIE) is a critical neonatal condition for which therapeutic hypothermia (TH) remains the cornerstone of neuroprotective intervention. Clinical observations a

O Osman Baştuğ

Evidence-Based Nursing Practices to Prevent Perioperative Unintentional Hypothermia in Elective Surgeries: An Observational Study

Ther Hypothermia Temp Manag. 2026 Dec;16(4):167-175. doi: 10.1177/21537658251414552. Epub 2026 Jan 15.ABSTRACTAlthough evidence-based recommendations for preventing perioperative unintentional hypothermia have long been available, observational studies evaluating their implementation in hospital pra

Ö Özlem Şahin Akboğa

Comparison of Long-Term Outcomes of Combined Hypothermia and Whole Body Cooling Therapy in Newborns with Hypoxic-Ischemic Encephalopathy

Ther Hypothermia Temp Manag. 2026 Dec;16(4):161-166. doi: 10.1177/21537658251415126. Epub 2026 Jan 12.ABSTRACTTherapeutic hypothermia is widely used as a neuroprotective intervention in infants with hypoxic-ischemic encephalopathy (HIE); however, limited data exist regarding the long-term neurodevel

N Nermin İsmayilova

Words That Heal: A Systematic Review of Healthcare Providers-Patient Communication to Enhance Chronic Care Management and Practice Recommendations

Health Commun. 2026 Oct 20:1-18. doi: 10.1080/10410236.2026.2749455. Online ahead of print.ABSTRACTChronic diseases represent a major global health burden, and suboptimal treatment adherence remains a key obstacle to long-term management. Healthcare provider (HCP)-patient communication is a modifiab

G Giada Pietrabissa

Aspiration Thrombectomy for High-Risk Pulmonary Embolism With Life-Threatening Anemia and Active Uterine Bleeding: A Case Report

Am J Case Rep. 2026 Oct 21;27:e954225. doi: 10.12659/AJCR.954225.ABSTRACTBACKGROUND High-risk pulmonary embolism (PE) carries significant mortality, and management becomes complex when it coexists with severe anemia and active bleeding, as thrombolysis is then contraindicated. We report the case of

O Okba Saoudi

Bipolar Disorder and the Risk of Cardiovascular Diseases: A Systematic Review and Meta-Analysis of Observational Studies

Acta Psychiatr Scand. 2026 Oct 20. doi: 10.1111/acps.70151. Online ahead of print.ABSTRACTINTRODUCTION: Bipolar disorder (BD) is a chronic psychiatric illness characterized by recurrent manic and depressive episodes, affecting 2% of the global population. It is associated with premature mortality, i

F Fernando Daibert de Souza Motta

Saponin extract from Astragalus membranaceus (Fisch.) Bunge regulates gut-brain axis through intestinal Escherichia coli to reduce cerebral oxidative stress to treat vascular dementia in rodents

Br J Pharmacol. 2026 Oct 20. doi: 10.1111/bph.70645. Online ahead of print.ABSTRACTBACKGROUND AND PURPOSE: Vascular dementia (VD) is a cognitive dysfunction syndrome caused by cerebrovascular diseases. Astragalus membranaceus (Fisch.) Bunge (AS) has antioxidative, gut microbiota-regulating, and cogn

W Wei Yin

Finerenone versus Steroidal MRAs in Type 2 Diabetes and Chronic Kidney Disease without Prior Heart Failure

ESC Heart Fail. 2026 Oct 19:xvag266. doi: 10.1093/eschf/xvag266. Online ahead of print.ABSTRACTAIMS: Type 2 diabetes (T2D) and chronic kidney disease (CKD) markedly increase the risk of heart failure (HF) and death. While finerenone improves outcomes in clinical trials, real-world evidence and direc

T Takefumi Kishimori

Risk prediction models for venous thromboembolism in the intensive care unit: a systematic review protocol assessing model performance, risk of bias, and clinical applicability

Syst Rev. 2026 Jul 25;15(1):277. doi: 10.1186/s13643-026-03259-x.ABSTRACTBACKGROUND: Venous thromboembolism (VTE) is a prevalent and serious complication in intensive care unit (ICU) patients, often leading to long-term issues, increased healthcare costs, and disrupted care. Given its preventable na

F Furong Zhu

Unilateral nonarteritic anterior ischemic optic neuropathy associated with obstructive sleep apnea-hypopnea syndrome: a case report

J Med Case Rep. 2026 Sep 24;20(1):642. doi: 10.1186/s13256-026-06598-4.ABSTRACTBACKGROUND: This report describes a case of obstructive sleep apnea-hypopnea syndrome (OSAHS) associated with nonarteritic anterior ischemic optic neuropathy (NAION). NAION is an optic neuropathy characterized by painless

C Chenjia Zhang

Superior sagittal sinus thrombosis with intracranial hemorrhage in a patient on infliximab: a case report

J Med Case Rep. 2026 Jul 25;20(1):645. doi: 10.1186/s13256-026-06355-7.ABSTRACTBACKGROUND: Superior sagittal sinus thrombosis (SSST) is a rare but life-threatening form of cerebral venous thrombosis. Although several prothrombotic and autoimmune conditions are recognized risk factors, SSST occurring

M Mohammad Rizwan Alam

Investigating long non-coding RNA (lncRNA) HOTAIR expression changes in ischemic stroke patients

BMC Res Notes. 2026 Jul 24;19(1):383. doi: 10.1186/s13104-025-07487-7.ABSTRACTBACKGROUND: Ischemic stroke (IS), a leading global health problem, is caused by interrupted blood flow in the brain, often due to clotting or artery constriction. Long non-coding RNAs (lncRNAs), particularly HOX transcript

A Alia Saberi

Aerobic exercise modulates macrophage polarization and promotes cardiac recovery after myocardial infarction in rats

J Cardiothorac Surg. 2026 Jul 24;21(1):824. doi: 10.1186/s13019-026-04603-x.ABSTRACTOBJECTIVE: To evaluate the protective effects of aerobic exercise (AE) on cardiac function and myocardial injury in rats with myocardial infarction (MI), as well as its impact on macrophage polarization.METHODS: A ra

M Mingyan Zhu

Outcomes of rescue procedures in patients undergoing unsuccessful deployment of transcatheter mitral valve replacement

J Cardiothorac Surg. 2026 Jul 25;21(1):828. doi: 10.1186/s13019-026-04666-w.ABSTRACTBACKGROUND: Perivalvular leak (PVL), valve embolization, and migration of valve in mitral position are critical complications of transcatheter mitral valve replacement (TMVR). To date, rescue strategies, and outcomes

C Chikashi Nakai

Sudden cardiac arrest during diagnostic workup: a rare case of high-risk interarterial left anterior descending artery anomaly

J Cardiothorac Surg. 2026 Jul 22;21(1):825. doi: 10.1186/s13019-026-04663-z.ABSTRACTBACKGROUND: Coronary artery anomalies are anatomical abnormalities involving abnormal origin, course, or termination of any of the three main epicardial arteries. These abnormalities may go unnoticed during a person'

Y Yorlenis Givairis Buzzelle Smith

Crystalloid vs colloid for Hemodynamics during Anesthesia INduction in TAVR patients (CHAIN-T): study protocol for a randomized controlled trial

Trials. 2026 Jul 24;27(1):616. doi: 10.1186/s13063-026-09906-x.ABSTRACTOBJECTIVE: To assess whether preload with colloids could reduce hypotension during induction in patients undergoing transcatheter aortic valve replacement (TAVR) compared to crystalloids.METHODS: This study is a single-center, pr

X Xiaoshuang Tuo

Effect of non-intubated spontaneous breathing video-assisted thoracoscopic surgery (NI-VATS) versus intubated general anesthesia (I-VATS) on the risk of postoperative venous thromboembolism

J Cardiothorac Surg. 2026 Jul 25;21(1):829. doi: 10.1186/s13019-026-04598-5.ABSTRACTBACKGROUND: By preserving spontaneous breathing and avoiding mechanical ventilation, Non-intubated video-assisted thoracoscopic surgery may attenuate perioperative inflammatory responses and promote early mobilizatio

J Jia Ye

Total and beverage-specific alcohol use at mid-life and all-cause and cause-specific mortality: a prospective cohort study

Nutr J. 2026 Jul 22;25(1):114. doi: 10.1186/s12937-026-01361-3.ABSTRACTBACKGROUND: While detrimental health impacts of excessive alcohol use are well-established, potential effects of low-to-moderate drinking remain controversial. We examined the associations between total and beverage-specific alco

Z Ziyue Li

GlycA-gene interactions in cardiovascular-kidney-metabolic syndrome: evidence from genetic association

Diabetol Metab Syndr. 2026 Jul 25;18(1):220. doi: 10.1186/s13098-026-02252-7.ABSTRACTOBJECTIVE: Cardiovascular-Kidney-metabolic (CKM) syndrome is a concept introduced by the American Heart Association, describing systemic diseases resulting from the pathophysiological interaction among obesity, stro

M Mingyang Yuan

Comorbidity patterns and inpatient expenditure among patients with coronary heart disease in China

BMC Public Health. 2026 Jul 25;26(1):3027. doi: 10.1186/s12889-026-28736-9.ABSTRACTBACKGROUND: Coronary heart disease (CHD) often co-occurs with other chronic conditions. This increases care complexity and hospital costs. Most previous studies have relied on single diseases or simple comorbidity cou

X Xiali Chen

Fetal cardiac interventions versus expectant management in congenital heart disease: a systematic review and meta-analysis

BMC Pregnancy Childbirth. 2026 Jul 24;26(1):1193. doi: 10.1186/s12884-026-09703-z.ABSTRACTOBJECTIVES: To evaluate biventricular circulation (BVC), live birth, and postnatal mortality after fetal cardiac intervention (FCI) compared with expectant management, and to examine outcomes according to techn

P Peng Ning

Sensory impairment, loneliness, and the emergence of physical-psychological-cognitive multimorbidity: a cross-national cohort study in China, the United States, and England

Int J Equity Health. 2026 Jul 24;25(1):248. doi: 10.1186/s12939-026-02958-0.ABSTRACTBACKGROUND: The co-occurrence of physical diseases, psychological disorders, and cognitive impairment-here termed physical-psychological-cognitive multimorbidity (PPC-M)-poses growing challenges to healthy aging but

Y Yilin Pan