Cardiac magnetic resonance imaging in coronary heart disease: IQWiG Reports - Commission No. D24-02

Cologne (Germany): Institute for Quality and Efficiency in Health Care (IQWiG); 2026 Feb 22.ABSTRACTRESEARCH QUESTION: The aim of this report is toassess the benefit of diagnostics using cardiac magnetic resonance imaging as part of a diagnostic strategy, compared with a diagnostic strategy without

I Institute for Quality and Efficiency in Health Care (IQWiG)

Development and explanation of electrocardiogram-based deep learning for predicting short-term mortality in heart failure patients

J Glob Health. 2026 Feb 13;16:04048. doi: 10.7189/jogh.16.04048.ABSTRACTBACKGROUND: Heart failure mortality has risen sharply after years of decline, highlighting the limitations of current risk assessment tools in accuracy, complexity, and cost, and the need for improved predictive models. To addre

Y Yan Li

Prevention and Treatment of Maternal Stroke in Pregnancy and Postpartum: A Scientific Statement From the American Heart Association

Obstet Gynecol. 2026 Feb 12. doi: 10.1097/AOG.0000000000006197. Online ahead of print.ABSTRACTStroke remains a rare but life-threatening complication of pregnancy, with significant implications for both maternal and fetal health. Current stroke prevention and treatment guidelines offer limited guida

E Eliza C Miller

IV Tenecteplase Before Thrombectomy Compared With Thrombectomy Alone in Patients With Stroke Due to a Large Vessel Occlusion

Neurology. 2026 Mar 24;106(6):e214702. doi: 10.1212/WNL.0000000000214702. Epub 2026 Feb 12.ABSTRACTBACKGROUND AND OBJECTIVES: The benefit of IV thrombolysis (IVT) with alteplase before endovascular thrombectomy (EVT) compared with EVT alone has been shown to be limited and time dependent. Data on te

G Gaspard Gerschenfeld

Timing of Hypertensive Disorders of Pregnancy in Nulliparous Individuals and Risk of Incident Chronic Hypertension 2-7 Years Postpartum

Obstet Gynecol. 2026 Feb 12. doi: 10.1097/AOG.0000000000006191. Online ahead of print.ABSTRACTOBJECTIVE: We sought to evaluate the association between the timing of new-onset hypertensive disorders of pregnancy (HDP) development (ie, antepartum, intrapartum, or postpartum) and the risk of incident h

A Alisse Hauspurg

Machine Learning for Predicting Venous Thromboembolism After Joint Arthroplasty: Systematic Review of Clinical Applicability and Model Performance

JMIR Med Inform. 2026 Feb 12;14:e79886. doi: 10.2196/79886.ABSTRACTBACKGROUND: There is increasing research on machine learning in predicting venous thromboembolism after joint arthroplasty, but the quality and clinical applicability of these models remain uncertain.OBJECTIVE: This systematic review

J Junwei Ma

Qian Yang Yu Yin Granule ameliorates hypertension-induced renal injury through the modulation of oxidative stress via Sestrin2 signaling pathway

J Pharm Pharmacol. 2026 Feb 6;78(2):rgag008. doi: 10.1093/jpp/rgag008.ABSTRACTOBJECTIVE: This study investigated the protective mechanisms of Qian Yang Yu Yin Granule (QYYYG) against hypertensive renal injury.METHODS: A hypertensive renal injury model was established in Spontaneous hypertensive rat

L Lichao Qian

Associations of unmet dental care needs due to cost with incident cardiovascular disease and dementia: a prospective study in the All of Us cohort

J Gerontol A Biol Sci Med Sci. 2026 Feb 12:glag023. doi: 10.1093/gerona/glag023. Online ahead of print.ABSTRACTBACKGROUND: Poor oral health among older adults may contribute to cardiovascular and dementia risk via systemic inflammation and cardiometabolic comorbidities. Financial constraints are a m

M Mabeline Velez

Rare, dangerous side effects from COVID-19 vaccines explained

Science. 2026 Feb 12;391(6786):647-648. doi: 10.1126/science.aeg3560. Epub 2026 Feb 12.ABSTRACTScientists discover why adenovirus-based shots caused life-threatening blood clots and bleeding in some patients.PMID:41678635 | DOI:10.1126/science.aeg3560

G Gretchen Vogel

Myelin sheaths in the central nervous system can withstand damage and dynamically remodel

Science. 2026 Feb 12;391(6786):eadr4661. doi: 10.1126/science.adr4661. Epub 2026 Feb 12.ABSTRACTMyelin damage is a hallmark of several neurological disorders, but how it occurs remains to be fully understood. In this study, we found that early damage in zebrafish and rodent demyelination models is c

D Donia Arafa

Gut-Heart Axis in Myocardial Repair: Mechanisms, Cross-Organ Networks, and Therapeutic Opportunities

Circ Res. 2026 Feb 13;138(4):e326978. doi: 10.1161/CIRCRESAHA.125.326978. Epub 2026 Feb 12.ABSTRACTCardiovascular diseases remain the leading global cause of morbidity and mortality, placing an escalating burden on health care systems and economies. While the gut microbiota is well recognized in ath

H Hung-Chih Chen

Cardiac findings in infants with in utero exposure to Zika virus - a follow up longitudinal study

PLoS Negl Trop Dis. 2026 Feb 12;20(2):e0014009. doi: 10.1371/journal.pntd.0014009. Online ahead of print.ABSTRACTBACKGROUND: Zika virus (ZIKV) is primarily known for its impact on the fetal central nervous system potentially leading to Congenital Zika Syndrome (CZS). Emerging evidence suggests ZIKV

B Brian N Dang

Predicting risk of ascending thoracic aortic aneurysm in asymptomatic adults using machine learning

PLoS One. 2026 Feb 12;21(2):e0342482. doi: 10.1371/journal.pone.0342482. eCollection 2026.ABSTRACTMost patients with ascending thoracic aortic aneurysms (ATAA) remain asymptomatic until they develop fatal complications, including aortic dissection and rupture. We aimed to develop and validate machin

S Seung Jae Lee

Meningeal lymphatic-associated brain swelling in acute stroke

PLoS One. 2026 Feb 12;21(2):e0342643. doi: 10.1371/journal.pone.0342643. eCollection 2026.ABSTRACTBrain meninges contain lymphatic vessels that play roles in clearance of extracellular solute in the central nervous system. But, whether and how the system is involved in acute stroke remains to be ful

R Rohan Mahesh Patil

Remdesivir may exacerbate ischemic acute kidney injury through molecular alterations in PGC-1α and apoptosis pathways: An in vivo study

PLoS One. 2026 Feb 12;21(2):e0336221. doi: 10.1371/journal.pone.0336221. eCollection 2026.ABSTRACTAcute kidney injury (AKI) represents a significant complication in patients with COVID-19. Although Remdesivir (RDV) has been shown to reduce viral loads and improve clinical outcomes, concerns persist

Y Yasin Bagheri

Does menopause influence the association between atherogenic index of plasma and prediabetes? A cross-sectional study in middle-aged Chinese women

PLoS One. 2026 Feb 12;21(2):e0342644. doi: 10.1371/journal.pone.0342644. eCollection 2026.ABSTRACTBACKGROUND: The atherogenic index of plasma (AIP) is a novel marker associated with the risk of prediabetes, yet its interplay with menopausal status remains unclear. This study aimed to investigate the

B Bin Ouyang

Rivaroxaban treatment discontinuation rates in patients with nonvalvular atrial fibrillation in Italian clinical practice: RITMUS-AF

PLoS One. 2026 Feb 12;21(2):e0341633. doi: 10.1371/journal.pone.0341633. eCollection 2026.ABSTRACTNonadherence to direct oral anticoagulant (DOAC) therapy exposes patients with nonvalvular atrial fibrillation (NVAF) to an increased risk of ischemic stroke and systemic embolism. Nevertheless, approxi

C Carmine Pizzi

Evaluation of the effectiveness of a multimodal aspiration prevention system in stroke rehabilitation nursing

PLoS One. 2026 Feb 12;21(2):e0342253. doi: 10.1371/journal.pone.0342253. eCollection 2026.ABSTRACTOBJECTIVE: To evaluate the efficacy of the Multimodal Aspiration Prevention System (MAPS) in reducing aspiration incidence, preventing pneumonia, and improving swallowing function in stroke rehabilitati

X Xibo Sun

Prevalence and determinants of hypertension among people living with HIV in Ghana: A cross-sectional study

PLoS One. 2026 Feb 12;21(2):e0342198. doi: 10.1371/journal.pone.0342198. eCollection 2026.ABSTRACTBACKGROUND: Hypertension is a major health concern in Sub-Saharan Africa (SSA). People living with human immunodeficiency virus (PLHIV) face unique risks for cardiometabolic disorders. However, the fact

K Kasim Abdulai

Cardiometabolic Syndromes and Associated Cardiovascular Risks: A Narrative Review

J Vasc Res. 2026 Feb 12:1-33. doi: 10.1159/000549775. Online ahead of print.ABSTRACTCardiovascular risk (CVR) represents a major global health challenge due to its strong association with metabolic and endocrine disorders. Conditions such as metabolic syndrome (MetS), hypertriglyceridemic waist (HTG

A Antonio Ruiz-Saavedra

Harnessing Targeted Polymerized Salicylic Acid Particles to Mitigate Neutrophil-Driven Inflammation

ACS Biomater Sci Eng. 2026 Feb 12. doi: 10.1021/acsbiomaterials.5c01278. Online ahead of print.ABSTRACTAcute inflammation is marked by the excessive and unregulated recruitment of neutrophils to inflamed or injured areas, which contribute to severe tissue damage in numerous inflammatory diseases. Th

M M Valentina Guevara

Hypertension is associated with knee osteoarthritis pain in an age-dependent manner

Exp Gerontol. 2025 Dec;212:112938. doi: 10.1016/j.exger.2025.112938. Epub 2025 Oct 25.ABSTRACTOBJECTIVE: Osteoarthritis (OA) is a painful and prevalent disease among older adults. Hypertension, commonly comorbid with OA and associated with aging, may influence OA pathology and pain. We hypothesized

C Carlos J Cruz

Multiple Myeloma: Morphofunctional Treatment Response Evaluation with Whole-Body Diffusion-weighted MRI and FDG PET/CT

Radiographics. 2026 Mar;46(3):e250082. doi: 10.1148/rg.250082.ABSTRACTWhole-body (WB) diffusion-weighted (DW) (WB-DW) MRI and fluorine 18-fluorodeoxyglucose (FDG) PET/CT have increasing roles in the evaluation of treatment response in the setting of multiple myeloma (MM), complementing molecular and

M Marcos Jiménez-Vázquez

RAB3GAP2 is a regulator of skeletal muscle endothelial cell proliferation and associated with capillary-to-fiber ratio

Cell Rep. 2026 Feb 11;45(2):116961. doi: 10.1016/j.celrep.2026.116961. Online ahead of print.ABSTRACTSkeletal muscle capillary density is correlated with physical performance and whole-body metabolic properties. Thus, we performed a genome-wide association study of skeletal muscle capillary-to-fiber

K Kristoffer Ström