Diagnostic performance of FIB-6 for identifying FibroScan-defined advanced fibrosis in Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD): a cross-sectional diagnostic accuracy study

BMC Gastroenterol. 2026 Aug 21;26(1):608. doi: 10.1186/s12876-026-05245-y.ABSTRACTBACKGROUND: Metabolic dysfunction-associated steatotic liver disease (MASLD) is a major cause of chronic liver disease worldwide. Accurate non-invasive identification of advanced fibrosis is essential for risk stratifi

H Hossein Bagheri

Cell-resolved testing of network-pharmacology candidates in dilated cardiomyopathy: PI3K-AKT-associated transcriptional differences are distributed across cardiac lineages and are not enriched above a genome-wide background

Funct Integr Genomics. 2026 Oct 3;26(1):280. doi: 10.1007/s10142-026-02059-9.ABSTRACTNetwork pharmacology nominates targets but cannot show that they are altered in the relevant cell, distinguishable from a hypothesis-free analysis of the same data, or linked to disease. Taking the candidates nomina

Y Yingying Qian

Room for Improvement: People living with diabetes in Canada are not receiving guideline-recommended preventive cardiovascular care: Analyses using the National Diabetes Repository

Prim Care Diabetes. 2026 Sep 22:S1751-9918(26)00179-8. doi: 10.1016/j.pcd.2026.09.003. Online ahead of print.ABSTRACTBACKGROUND: To reduce cardiovascular morbidity and mortality, people living with diabetes should receive guideline-recommended care. This study aimed to determine whether people livin

K Katharine Mackett

SERINC2: From membrane lipid synthesis to human disease

Life Sci. 2026 Oct 2:124718. doi: 10.1016/j.lfs.2026.124718. Online ahead of print.ABSTRACTAIMS: This review aims to summarize current evidence on the role of serine incorporator 2 (SERINC2) in human disease, focusing on how its function in serine-associated membrane lipid biosynthesis-particularly

C Changgyu Son

Depressive symptom profiles and risk of cardiometabolic disease incidence

J Affect Disord. 2026 Oct 2:122580. doi: 10.1016/j.jad.2026.122580. Online ahead of print.ABSTRACTINTRODUCTION: Major depressive disorder (MDD) has been linked to increased incidence of cardiometabolic disease (CMD). Depressive symptom profiles associated with inflammation (atypical energy-related s

J J C Zwiep