Macrophage extracellular traps accelerate atherosclerosis progression via Rap1 pathway-mediated necroptosis and phenotypic switching in vascular smooth muscle cells

J Transl Med. 2026 Jul 11. doi: 10.1186/s12967-026-07860-5. Online ahead of print.ABSTRACTBACKGROUND: Atherosclerosis (AS) is a primary driver of cardiovascular diseases, with vascular smooth muscle cell (VSMC) fate being critical for plaque stability. Macrophage extracellular traps (METs) are impli

S Suli Wang

Frailty may confound the association between MASLD and cardiovascular mortality in people with cardiometabolic risk factors

Cardiovasc Diabetol. 2026 Jul 11. doi: 10.1186/s12933-026-03284-z. Online ahead of print.ABSTRACTBACKGROUND: While metabolic dysfunction-associated steatotic liver disease (MASLD) has been consistently associated with increased cardiovascular risk in the general population, its association with card

R Ruoting Wang

Lipoprotein(a) and atherosclerosis risk across estimated glucose disposal rate strata: evaluating synergistic predictive utility

Lipids Health Dis. 2026 Jul 11. doi: 10.1186/s12944-026-03014-0. Online ahead of print.ABSTRACTBACKGROUND: High lipoprotein(a) [Lp(a)] levels and insulin resistance (IR) are both established risk factors for atherosclerosis. Nevertheless, the interrelationship between these two factors and their com

Y Yihui Li

Association of carotid artery calcifications detected on panoramic radiographs with systemic diseases in dental implant patients: a cross-sectional study in a Turkish population

BMC Oral Health. 2026 Jul 11. doi: 10.1186/s12903-026-09098-5. Online ahead of print.ABSTRACTBACKGROUND: Carotid artery calcification (CAC) detected on panoramic radiographs can serve as an early indicator of systemic atherosclerotic disease. This study aimed to determine the prevalence of CAC in di

M Muhammet Bahattin Bingul

A systematic review of patient decision aids for hypertension

BMC Med Inform Decis Mak. 2026 Jul 11;26(1):259. doi: 10.1186/s12911-026-03700-0.ABSTRACTBACKGROUND: Hypertension is a major cause of premature death and a modifiable risk factor for cardiovascular disease. Effective management includes both pharmacological treatment strategies, including antihypert

J Jan Berghold

Threshold effect of the METS-VF index on hyperuricemia in adults with hypertension: a cross-sectional study

BMC Endocr Disord. 2026 Jul 11. doi: 10.1186/s12902-026-02415-7. Online ahead of print.ABSTRACTBACKGROUND: Hyperuricemia (HUA) is a major public health concern that is closely linked to obesity. The novel visceral adiposity index (METS-VF) demonstrates significant associations with multiple chronic

M Meihui Wu

Incremental prognostic value of the systemic immune‑inflammation index, pan‑immune‑inflammation value, and modified glasgow prognostic score for severity assessment and outcome prediction in community‑acquired pneumonia

BMC Pulm Med. 2026 Jul 11. doi: 10.1186/s12890-026-04422-9. Online ahead of print.ABSTRACTBACKGROUND: Community-acquired pneumonia (CAP) constitutes a significant cause of hospital admissions and mortality globally. Accurate assessment of CAP severity and prognosis is crucial for optimizing treatmen

Y Yunkui Li

Comparison of vasodilators for heart failure: a systematic review and network meta-analysis of RCTs

BMC Cardiovasc Disord. 2026 Jul 11. doi: 10.1186/s12872-026-06278-7. Online ahead of print.ABSTRACTBACKGROUND: The effect of vasodilators in the management of heart failure (HF) remains inconclusive. This study aims to evaluate and compare the overall benefits of vasodilators to patients with HF.MET

Q Qin Zhao

ECG parameters to detect cardiac involvement in Fabry disease

BMC Cardiovasc Disord. 2026 Jul 11. doi: 10.1186/s12872-026-06279-6. Online ahead of print.ABSTRACTBACKGROUND: Cardiac involvement of the disease is a leading cause of death and disability in Fabry disease characterized by pathological accumulation of globotriaosylceramide (Gb3) and lyso-globotriaos

Y Yu Wang

Single-cell RNA sequencing and cross-species analysis revealed the role of T cell-driven inflammatory responses in the pathogenesis of aortic dissection

BMC Cardiovasc Disord. 2026 Jul 11. doi: 10.1186/s12872-026-06275-w. Online ahead of print.ABSTRACTBACKGROUND: Aortic dissection (AD) is a life-threatening vascular condition characterized by acute inflammation and structural deterioration of the aortic wall. This study aimed to delineate the immune

S Shen Zhang

Association of TNNI3 and MYBPC3 variants with clinical phenotype and metabolic disorders in patients with hypertrophic cardiomyopathy

BMC Cardiovasc Disord. 2026 Jul 11. doi: 10.1186/s12872-026-06265-y. Online ahead of print.ABSTRACTINTRODUCTION: Hypertrophic cardiomyopathy is an inherited cardiovascular disease with heterogeneous presentation. However, the metabolic changes resulting from mutations and their relationship to the p

H Hao Wu

Analysis of factors associated with poor R-wave progression in precordial leads in patients with acute pulmonary thromboembolism: a retrospective study

BMC Cardiovasc Disord. 2026 Jul 11. doi: 10.1186/s12872-026-06243-4. Online ahead of print.ABSTRACTBACKGROUND: Acute pulmonary thromboembolism (APE) presents with nonspecific clinical manifestations, and the classic electrocardiogram (ECG) abnormalities associated with it have limited sensitivity. P

X Xiaomei Wu

MiR-378a-3p Promotes Macrophage Polarization from M1 to M2 for Cardiac Repair after Infarction Via Trem1

J Cardiovasc Transl Res. 2026 Jul 11;19(1):88. doi: 10.1007/s12265-026-10815-2.ABSTRACTAcute myocardial infarction (AMI) triggers a robust inflammatory response in which macrophage polarization critically influences cardiac repair, yet the regulatory role of microRNAs remains largely undefined. Thro

M Ming Shen

Mortality trends and demographics due to hypertensive nephrosclerosis in older adults from 1999-2020

J Hum Hypertens. 2026 Jul 11. doi: 10.1038/s41371-026-01175-0. Online ahead of print.ABSTRACTHypertensive Nephrosclerosis (HSN), a progressive kidney disease, has significantly impacted mortality and morbidity, via cardiovascular events, end-stage renal disease, and infections. Despite its clinical

F Fnu Kalpina

A systematic review examining the association between parity and gravidity & hypertension and blood pressure

NPJ Cardiovasc Health. 2026 Jul 11. doi: 10.1038/s44325-026-00143-4. Online ahead of print.ABSTRACTParity and gravidity have been shown to be associated with hypertension and changes in blood pressure, but results are conflicting. We aimed to estimate the association between gravidity and parity wit

N Nabilah Gulamhusein

Long-term exposure to air pollution and chronic kidney disease incidence in adults: The Danish Nurse Cohort

J Expo Sci Environ Epidemiol. 2026 Jul 11. doi: 10.1038/s41370-026-00943-x. Online ahead of print.ABSTRACTBACKGROUND: Air pollution is an established risk factor for cardiovascular and metabolic diseases, but evidence on chronic kidney diseases (CKD) remains limited.OBJECTIVE: We aim to examine the

G Gonzalo B Hevia-Ramos

Single lead electrocardiographic detection of left ventricular systolic dysfunction in pediatric and congenital heart disease

NPJ Digit Med. 2026 Jul 11. doi: 10.1038/s41746-026-02646-x. Online ahead of print.ABSTRACTPortable, scalable, and accessible artificial intelligence (AI)-enabled smartwatch technology shows promise as a cardiovascular risk stratification strategy in the general adult population. The challenges of l

J Joshua Mayourian

Scalable risk stratification of undiagnosed heart failure using routine health data and its association with imaging phenotypes and outcomes

Sci Rep. 2026 Jul 11. doi: 10.1038/s41598-026-60673-w. Online ahead of print.ABSTRACTLate diagnosis of Heart failure (HF) is associated with worse outcomes. We aimed to develop a scalable tool to identify those at high risk of undiagnosed HF using routine electronic health records (EHR). We develope

Y Yoko M Nakao

A Decade of the YODA Project: Advancing Clinical Trial Data Sharing through Transparency, Independence, and Collaboration

Sci Data. 2026 Jul 11. doi: 10.1038/s41597-026-07854-4. Online ahead of print.ABSTRACTThe Yale University Open Data Access (YODA) Project, in partnership with Johnson & Johnson since 2014, is an academic-led initiative that promotes independent, transparent, and responsible sharing of clinical trial

E Erfan Taherifard

Calcium signaling pathway implicates a shared genetic basis between psychiatric and cardiovascular diseases

Transl Psychiatry. 2026 Jul 11. doi: 10.1038/s41398-026-04222-z. Online ahead of print.ABSTRACTPsychiatric and cardiovascular diseases (CVDs) are frequently comorbid and are interconnected through the brain-heart axis. However, the underlying shared genetic etiology remains unknown in East Asians. T

Y Yunqing Zhu

Reversal of canonical Wnt/β-catenin signaling pathway attenuates gestational diabetes mellitus-induced offspring cardiac hypertrophy: mechanistic insights into pathological remodeling

Nutr Diabetes. 2026 Jul 11. doi: 10.1038/s41387-026-00453-7. Online ahead of print.ABSTRACTBACKGROUND: Gestational diabetes mellitus (GDM), a prevalent prenatal metabolic disorder characterized by hyperglycemia occurring in approximately 9.2% of pregnancies globally, imposes significant cardiovascul

X Xun Yuan

The landscape of plasma proteomic links to human organ imaging

Nat Commun. 2026 Jul 11. doi: 10.1038/s41467-026-74715-4. Online ahead of print.ABSTRACTPlasma protein levels provide important insights into human disease, yet a comprehensive assessment of plasma proteomics across organs is lacking. Using large-scale multimodal data from the UK Biobank, we integra

Z Zirui Fan

Severe OSA May Be Associated With Endothelial Dysfunction in Patients With Nocturnal Hypertension

Arch Bronconeumol. 2026 Jul 11:S0300-2896(26)00241-3. doi: 10.1016/j.arbres.2026.06.007. Online ahead of print.ABSTRACTINTRODUCTION: Nocturnal hypertension (NH) is a high-risk, underdiagnosed blood pressure (BP) phenotype strongly associated with cardiovascular morbidity. Obstructive sleep apnea (OS

K Krish Dodani

Improving Health Equity in Hypertension Control for Black Patients

Jt Comm J Qual Patient Saf. 2026 Jun 23:S1553-7250(26)00160-1. doi: 10.1016/j.jcjq.2026.06.008. Online ahead of print.ABSTRACTBACKGROUND: Hypertension is a significant risk factor for cardiovascular disease, which remains the leading cause of death in the United States. Inequities in blood pressure

C Catherine T Harper