Elife. 2025 Dec 11;14:RP106231. doi: 10.7554/eLife.106231.ABSTRACTHypoplastic left heart syndrome (HLHS) is the most lethal congenital heart disease (CHD) whose genetic basis remains elusive, likely due to oligogenic complexity. To identify regulators of cardiomyocyte (CM) proliferation relevant to
JAMA Netw Open. 2025 Dec 1;8(12):e2547584. doi: 10.1001/jamanetworkopen.2025.47584.ABSTRACTIMPORTANCE: Intraventricular hemorrhage (IVH) is a significant complication of preterm birth, affecting approximately 20% of preterm infants. Despite its prevalence, the effect of IVH beyond the impact of prem
Discov Oncol. 2025 Dec 11. doi: 10.1007/s12672-025-04257-6. Online ahead of print.ABSTRACTORC1 is a core protein governing DNA replication initiation and cell cycle regulation, exhibiting significant overexpression in multiple malignancies where it correlates with advanced disease stage and poor pro
Heart Fail Rev. 2025 Dec 11;31(1):13. doi: 10.1007/s10741-025-10587-y.ABSTRACTChronic heart failure with reduced ejection fraction (HFrEF) is a progressive syndrome associated with substantial residual morbidity and mortality despite contemporary guideline-directed medical therapy (GDMT) - angiotens
Acta Neuropathol. 2025 Dec 11;150(1):64. doi: 10.1007/s00401-025-02970-8.ABSTRACTThe etiology of cerebrovascular pathology is heterogeneous. Independent or synergistic role of this pathology relative to Alzheimer's disease (AD) pathology is necessary to clarify distinct neurodegenerative pathways. W
J Immigr Minor Health. 2025 Dec 11. doi: 10.1007/s10903-025-01812-9. Online ahead of print.ABSTRACTSelf-efficacy theory proposes that confidence to engage in a health behavior is associated with engaging in that specific behavior. Most research examining self-efficacy has been conducted with white y
Cardiovasc Drugs Ther. 2025 Dec 11. doi: 10.1007/s10557-025-07819-6. Online ahead of print.ABSTRACTPURPOSE: Obstructive sleep apnea promotes atrial fibrillation (AF) by activating the renin-angiotensin system (RAS) and increasing angiotensin II. Alamandine(ALA), an angiotensin(1-7)-related peptide w
No abstractActa Neuropathol. 2025 Dec 11;150(1):63. doi: 10.1007/s00401-025-02966-4.NO ABSTRACTPMID:41379219 | DOI:10.1007/s00401-025-02966-4
Neurosurg Rev. 2025 Dec 11;49(1):62. doi: 10.1007/s10143-025-03957-5.ABSTRACTSpontaneous subarachnoid hemorrhage (SAH) is most often caused by rupture of an intracranial aneurysm. However, in approximately 15-20% of cases, no clear source of bleeding can be identified. While angiogram-negative perim
No abstractArq Bras Cardiol. 2025 Dec 1;122(9):e20250621. doi: 10.36660/abc.20250621.NO ABSTRACTPMID:41379177 | DOI:10.36660/abc.20250621
Arq Bras Cardiol. 2025 Dec 1;122(9):e20240777. doi: 10.36660/abc.20240777. eCollection 2025.ABSTRACTBACKGROUND: Handgrip strength (HGS) is a key indicator of overall muscle strength and functional capacity in patients with heart failure (HF). However, no reference equations specific to this populati
Arq Bras Cardiol. 2025 Dec 1;122(9):e20240425. doi: 10.36660/abc.20240425. eCollection 2025.ABSTRACTBACKGROUND: In recent years, the impact of diet and lifestyle on coronary heart disease (CHD) has garnered significant attention. Caffeine, a common dietary component, and its metabolites may influenc
Arq Bras Cardiol. 2025 Dec 1;122(9):e20240329. doi: 10.36660/abc.20240329. eCollection 2025.ABSTRACTBACKGROUND: Both fondaparinux and radial access have been associated with lower rates of major adverse cardiovascular events (MACE) in acute coronary syndrome (ACS).OBJECTIVE: To evaluate the associat
Rev Paul Pediatr. 2025 Dec 1;43:e2024311. doi: 10.1590/1984-0462/2025/43/2024311. eCollection 2025.ABSTRACTOBJECTIVE: DiGeorge syndrome (DGS) is characterized by facial dysmorphisms, congenital heart defects, palatal abnormalities, hypocalcemia, immunodeficiency, and neurodevelopmental deficits. Gro
Food Funct. 2025 Dec 11. doi: 10.1039/d5fo03952e. Online ahead of print.ABSTRACTBackground & Purpose: While inflammation and oxidative stress contribute to renal injury, evidence linking dietary inflammatory/antioxidant potential to chronic kidney disease (CKD) incidence remains limited. We investig
JACC Asia. 2025 Dec 4:S2772-3747(25)00596-4. doi: 10.1016/j.jacasi.2025.10.017. Online ahead of print.ABSTRACTCardiovascular diseases (CVDs) are the leading cause of mortality worldwide, with their prevalence rising with advancing age. Progressive remodeling of the cardiovascular system during aging
JACC Case Rep. 2025 Dec 11:106423. doi: 10.1016/j.jaccas.2025.106423. Online ahead of print.ABSTRACTWe present a case of a 35-year-old man with no prior history of hypertension or diabetes who was admitted with non-ST-elevation acute coronary syndrome. The patient was hemodynamically stable, and his
JACC Case Rep. 2025 Dec 11:106488. doi: 10.1016/j.jaccas.2025.106488. Online ahead of print.ABSTRACTBACKGROUND: The optimal timing and indications for corticosteroid therapy in patients with suspected immune checkpoint inhibitor (ICI)-associated myocarditis and isolated cardiac troponin (cTn) elevat
JACC Case Rep. 2025 Dec 11:106306. doi: 10.1016/j.jaccas.2025.106306. Online ahead of print.ABSTRACTBACKGROUND: Merkel cell carcinoma (MCC) is an aggressive neuroendocrine malignancy with high metastatic potential. Cardiac involvement is rare and usually occurs late in the disease course.FIRST-IN-HU
JACC Cardiovasc Imaging. 2025 Dec 9:S1936-878X(25)00631-X. doi: 10.1016/j.jcmg.2025.10.020. Online ahead of print.ABSTRACTAtherosclerotic cardiovascular disease (ASCVD), in particular atherosclerotic coronary artery disease (CAD), is the leading cause of death in the United States and globally. In t
Biometrics. 2025 Oct 8;81(4):ujaf159. doi: 10.1093/biomtc/ujaf159.ABSTRACTThe mean survival is the key ingredient of the decision process in several applications, notably in health economic evaluations. It is defined as the area under the complete survival curve, thus necessitating extrapolation of
Radiol Cardiothorac Imaging. 2025 Dec;7(6):e250206. doi: 10.1148/ryct.250206.ABSTRACTCardiac herniation describes displacement of the heart from its expected location through a defect in the pericardium that is congenital, traumatic, or iatrogenic in origin. While rare, early recognition and treatme
Radiol Cardiothorac Imaging. 2025 Dec;7(6):e250071. doi: 10.1148/ryct.250071.ABSTRACTPurpose To compare the performance of cardiac CT-derived hybrid aortic valve area (AVA) and planimetry, in combination with aortic valve calcium (AVC) or AVC density (AVCd), for assessing low-gradient aortic stenosi
Radiol Cardiothorac Imaging. 2025 Dec;7(6):e240495. doi: 10.1148/ryct.240495.ABSTRACTPurpose To evaluate the feasibility of performing pulse oximetry-triggered coronary CT angiography (CCTA) for diagnostic imaging in cardiac participants who cannot or have difficulty being connected to electrocardio
