Front Biosci (Landmark Ed). 2025 Nov 26;30(11):40737. doi: 10.31083/FBL40737.ABSTRACTIschemic stroke ranks among the leading global causes of death and disability, driven by intricate mechanisms such as neuronal injury, inflammation, and oxidative stress. Emerging as a pivotal player in ischemic str
Front Biosci (Landmark Ed). 2025 Nov 26;30(11):46326. doi: 10.31083/FBL46326.ABSTRACTBACKGROUND: Although epirubicin is used among therapeutic options for multiple myeloma (MM), its clinical use remains limited, in part because the subgroup of patients most likely to benefit has not been clearly def
Rev Neurol. 2025 Nov 30;80(10):38627. doi: 10.31083/RN38627.ABSTRACTOBJECTIVE: To investigate the optimal timing of stereotactic minimally invasive surgery (SMIS) in individuals with supratentorial intracerebral hemorrhage (sICH) and brain herniation.METHOD: A retrospective analysis was conducted on
Rev Neurol. 2025 Nov 30;80(10):40923. doi: 10.31083/RN40923.ABSTRACTOBJECTIVES: There are inherent risks associated with intravenous thrombolysis (IVT) therapy in patients with acute ischemic stroke (AIS). The atherogenic index of plasma (AIP), defined as log (triglyceride [TG]/high-density lipoprot
Rev Neurol. 2025 Nov 30;80(10):40930. doi: 10.31083/RN40930.ABSTRACTBACKGROUND: Oculomotor nerve palsy (ONP) is a condition characterized by ptosis, restricted eye movement, and pupillary abnormalities, with causes ranging from congenital to acquired factors. Among these, posterior communicating art
Expert Opin Pharmacother. 2025 Dec 6. doi: 10.1080/14656566.2025.2601062. Online ahead of print.ABSTRACTINTRODUCTION: Lipoprotein(a) [Lp(a)] is established as an independent risk factor for atheromatous cardiovascular disease and aortic valve stenosis. Currently available lipid-lowering pharmacother
Expert Opin Pharmacother. 2025 Dec 6. doi: 10.1080/14656566.2025.2601060. Online ahead of print.ABSTRACTBACKGROUND: Obesity is a chronic disease with significant global health repercussions. GLP-1 receptor agonists (GLP-1RAs) and dual GIP/GLP-1 receptor agonists (GIP/GLP-1RAs) are now established, e
Public Health Res (Southampt). 2025 Dec 3:1-17. doi: 10.3310/GJMW1501. Online ahead of print.ABSTRACTBACKGROUND: The United Kingdom Soft Drinks Industry Levy was introduced in April 2018, resulting both in changes in sugar levels in drinks and purchases of drinks. Both mechanisms could impact on the
Nutr Clin Pract. 2025 Dec 5. doi: 10.1002/ncp.70074. Online ahead of print.ABSTRACTObesity is common, affecting >40% of Americans and increasing at rapid rates worldwide. Defined by the presence of excess body fat, obesity is tied to a multitude of poor health conditions, including cardiovascular di
Physiol Rep. 2025 Dec;13(23):e70693. doi: 10.14814/phy2.70693.ABSTRACTDispersion of repolarization results from a non-homogeneous recovery of excitability in cardiac tissue, and it is an important factor in arrhythmogenesis because it could lead to the initiation and maintenance of a variety of arrh
Eur J Cardiothorac Surg. 2025 Dec 1;67(12):ezaf348. doi: 10.1093/ejcts/ezaf348.ABSTRACTOBJECTIVES: To critically appraise the design of the ongoing multicentre, randomized START YOUNG trial comparing transcatheter aortic valve implantation (TAVI) with bioprosthetic surgical aortic valve replacement
Clin Exp Hypertens. 2025 Dec 31;47(1):2595154. doi: 10.1080/10641963.2025.2595154. Epub 2025 Dec 5.ABSTRACTHypertension and Alzheimer's disease (AD) are common comorbidities that seriously damage the health of the elderly. This review lays out the complex bidirectional association between hypertensi
Physiother Res Int. 2026 Jan;31(1):e70133. doi: 10.1002/pri.70133.ABSTRACTBACKGROUND AND PURPOSE: To describe the development of an mHealth app that includes various instruments for the assessment of individuals with stroke.METHODS: The app was developed following the report by the Agency for Health
BMC Psychol. 2025 Dec 5;13(1):1335. doi: 10.1186/s40359-025-03693-x.ABSTRACTBACKGROUND: Illness perceptions, which are representations of illness or health threats formed in response to situational stimuli, are considered one of the most significant predictors of self-care behaviors. However, there
J Transl Med. 2025 Dec 5;23(1):1382. doi: 10.1186/s12967-025-07402-5.ABSTRACTFoam cells play a crucial role in the formation and progression of atherosclerotic plaque. In addition to classical monocytes and vascular smooth muscle cells (VSMCs), foam cells can also originate from dendritic cells, end
Stem Cell Res Ther. 2025 Dec 5. doi: 10.1186/s13287-025-04845-x. Online ahead of print.ABSTRACTCardiovascular diseases (CVDs), particularly myocardial infarction (MI), cause irreversible cardiomyocyte loss and scar formation, severely compromising cardiac function. Despite advances in cardiovascular
BMC Cancer. 2025 Dec 5. doi: 10.1186/s12885-025-15303-5. Online ahead of print.ABSTRACTINTRODUCTION: Children and adolescents, diagnosed with cancer, frequently develop physical and cognitive impairments. Hence, cancer and its treatments contribute to reduced physical activity (PA) and cognitive imp
BMC Cardiovasc Disord. 2025 Dec 5. doi: 10.1186/s12872-025-05417-w. Online ahead of print.ABSTRACTBACKGROUND: Novel therapeutic agents have substantially improved multiple myeloma (MM) survival, making cardiovascular disease (CVD) a predominant cause of non-cancer mortality. Because MM predominantly
Mil Med Res. 2025 Dec 5;12(1):89. doi: 10.1186/s40779-025-00674-4.ABSTRACTBACKGROUND: Type 2 diabetes (T2D) is a global epidemic that reduces life expectancy. Evidence is limited on the benefits of achieving multiple guideline-recommended targets and cross-country differences. This study aimed to qu
Eur J Med Res. 2025 Dec 5;30(1):1211. doi: 10.1186/s40001-025-03439-w.ABSTRACTNon-obstructive myocardial stunning is characterized by transient myocardial contractile dysfunction despite preserved coronary perfusion. Although increasingly recognized, it remains a diagnostic and therapeutic challenge
J Nanobiotechnology. 2025 Dec 6;23(1):758. doi: 10.1186/s12951-025-03857-2.ABSTRACTAtherosclerosis (AS) is a leading cause of cardiovascular mortality worldwide, highlighting an urgent need for innovative, non-invasive therapies to address plaque instability and acute cardiovascular events. Ultrasou
J Coll Physicians Surg Pak. 2025 Dec;35(12):1541-1545. doi: 10.29271/jcpsp.2025.12.1541.ABSTRACTOBJECTIVE: To investigate the impact of plasma homocysteine (Hcy) levels on the cardiac valve calcification (CVC) in patients undergoing maintenance haemodialysis (MHD).STUDY DESIGN: A retrospective obser
J Coll Physicians Surg Pak. 2025 Dec;35(12):1521-1525. doi: 10.29271/jcpsp.2025.12.1521.ABSTRACTOBJECTIVE: To compare distal transradial access (dTRA) via the anatomical snuffbox as an alternative to conventional transradial access (TRA) for coronary angiography and angioplasty in terms of clinical
BMC Genomics. 2025 Dec 6. doi: 10.1186/s12864-025-12271-9. Online ahead of print.ABSTRACTAge is a major risk factor for various diseases, such as cancer, cardiovascular conditions, and neurodegenerative diseases. However, chronological age, the simple number of years one has lived, does not capture
