C-C chemokine receptor type 2 (CCR2)^(+) monocytes and macrophages play a critical role in cardiovascular inflammation. In this study, we developed an ^(18)F-labeled CCR2-targeted positron emission tomography (PET) radiotracer, [^(18)F]AlF-NOTA-PEG(2)-ECL1i, for the noninvasive imaging of cardiac in
Cardiol Rev. 2026 May 14. doi: 10.1097/CRD.0000000000001277. Online ahead of print.ABSTRACTChimeric antigen receptor T-cell (CAR-T) therapy has revolutionized the treatment landscape of relapsed or refractory hematologic malignancies, offering unprecedented response rates and durable remissions in d
Adv Gerontol. 2026;39(1):99-105. doi: 10.34922/AE.2026.39.1.011.ABSTRACTExercise tolerance, determined in the early stages of cardiac rehabilitation during exercise tests upon discharge from the hospital, is an important functional indicator of the cardiovascular system in patients with coronary hea
Adv Gerontol. 2026;39(1):82-90. doi: 10.34922/AE.2026.39.1.009.ABSTRACTAtherosclerosis is a chronic disease of the arterial wall, which involves both innate and adaptive immune mechanisms. With the development and progression of atherosclerosis, there is a violation of the process regulation the ton
Adv Gerontol. 2026;39(1):74-81. doi: 10.34922/AE.2026.39.1.008.ABSTRACTAging is recognized as a highly complex process mediated by multiple mechanisms. It affects all body systems, including the cardiovascular system. The severity of age-related changes in the body is often associated with the sever
Adv Gerontol. 2026;39(1):64-68. doi: 10.34922/AE.2026.39.1.006.ABSTRACTHeart failure, including chronic heart failure (CHF) is an inevitable progressive disease worldwide. In the developed countries the amount of patient with such disease is approximately 2% of total adult population. Besides the pr
Adv Gerontol. 2026;39(1):55-63. doi: 10.34922/AE.2026.39.1.005.ABSTRACTChronic heart failure (CHF) is the most common pathological condition in geriatric practice. The increasing prevalence of CHF with age is driven by the rapid global rise in non-communicable diseases (NCDs) such as obesity, arteri
Circulation. 2026 May 19;153(20):1573-1592. doi: 10.1161/CIRCULATIONAHA.125.065903. Epub 2026 May 18.ABSTRACTIt has long been accepted that observational analyses have an important role in evaluating use patterns and assessing the safety of different treatments, including cardiovascular devices, in
No abstractCirculation. 2026 May 19;153(20):1523-1525. doi: 10.1161/CIRCULATIONAHA.126.079488. Epub 2026 May 18.NO ABSTRACTPMID:42149995 | DOI:10.1161/CIRCULATIONAHA.126.079488
J Med Internet Res. 2026 May 18;28:e81938. doi: 10.2196/81938.ABSTRACTBACKGROUND: Poststroke dysarthria, a common speech impairment, affects up to half of all stroke survivors, often reducing their ability to communicate, and adversely affecting their quality of life. Although conventional speech th
Eur Heart J. 2026 May 18:ehag357. doi: 10.1093/eurheartj/ehag357. Online ahead of print.ABSTRACTHomozygous familial hypercholesterolaemia (HoFH) is a rare genetic disorder marked by extremely elevated low-density lipoprotein cholesterol (LDL-C) levels from birth and a very high risk of premature ath
Eur Heart J. 2026 May 18:ehag293. doi: 10.1093/eurheartj/ehag293. Online ahead of print.ABSTRACTBACKGROUND AND AIMS: Fatal ventricular tachyarrhythmias (FVTs) are a major cause of sudden cardiac death globally. Despite their clinical importance, current antiarrhythmic therapies remain constrained by
PLoS One. 2026 May 18;21(5):e0349511. doi: 10.1371/journal.pone.0349511. eCollection 2026.ABSTRACTClinical evidence suggests that essential hypertension is linked to oxidative stress and inflammatory infiltration, which can complicate osteoporosis. Edible house crickets (Acheta domesticus) are novel
PLoS One. 2026 May 18;21(5):e0341044. doi: 10.1371/journal.pone.0341044. eCollection 2026.ABSTRACTBACKGROUND: Interleukin-17A (IL-17A) is a key Th17 cytokine involved in mucosal defense and chronic inflammation and serves as an important biomarker and therapeutic target in autoimmune, cardiovascular
J Vasc Res. 2026 May 18:1-16. doi: 10.1159/000552592. Online ahead of print.ABSTRACTHydrogen sulfide (H2S) is a gaseous signalling molecule with vasodilatory properties and regulates inflammation and fibrosis in the liver. Rats with bile duct ligation-induced liver disease were treated with propargy
J Vis Exp. 2026 Apr 30;(230). doi: 10.3791/70675.ABSTRACTDiabetic macular edema (DME) is a leading cause of blindness involving vascular endothelial growth factor (VEGF) leakage and inflammation. This retrospective, single-center cohort study evaluated the efficacy and safety of intravitreal anti-VE
J Vis Exp. 2026 Apr 30;(230). doi: 10.3791/70679.ABSTRACTThis observational matched cohort study evaluated the combined use of angiotensin receptor blockers (ARBs) and calcium channel blockers (CCBs) in high-risk hypertensive patients to optimize treatment strategies. A total of 330 high-risk hypert
J Vis Exp. 2026 Apr 30;(230). doi: 10.3791/69971.ABSTRACTThis assessor-blinded randomized controlled trial evaluated whether a standardized plantar needle-pricking protocol designed to evoke the nociceptive withdrawal reflex (NWR) improves early lower-limb motor recovery in post-stroke flaccid hemip
IEEE J Biomed Health Inform. 2026 May 18;PP. doi: 10.1109/JBHI.2026.3694291. Online ahead of print.ABSTRACTAutomatic segmentation of the vessel wall in three-dimensional (3D) carotid artery (CA) ultrasound (US) images can significantly advance the development of cardiovascular disease risk predictio
J Mol Endocrinol. 2026 May 18:JME-25-0134. doi: 10.1530/JME-25-0134. Online ahead of print.ABSTRACTThe late 20th century saw major advances in mapping genes and mutations in endocrine disorders, driven by biochemical studies that identified defects endocrinologically and by family-based studies that
Clin J Am Soc Nephrol. 2026 May 18. doi: 10.2215/CJN.0000001116. Online ahead of print.ABSTRACTThe kidney plays the major role in the maintenance of acid-base balance by reabsorbing the daily filtered load of bicarbonate and generating sufficient base to neutralize the acid produced by metabolism of
J Proteome Res. 2026 May 18. doi: 10.1021/acs.jproteome.6c00027. Online ahead of print.ABSTRACTSaliva remains underexplored in metabolomics compared with widely used biofluids such as blood and urine. However, its noninvasive, rapid, and cost-effective collection, together with its suitability for s
Eur Heart J Cardiovasc Pharmacother. 2026 May 18:pvag019. doi: 10.1093/ehjcvp/pvag019. Online ahead of print.ABSTRACTAIMS: In chronic heart failure (HF), decongestion is hindered by reduced renal function and diuretic resistance. This study compared the effect of eGFR and serum bicarbonate on three
Egypt Heart J. 2026 May 18;78(1):34. doi: 10.1186/s43044-026-00746-3.ABSTRACTBACKGROUND: Cardiovascular diseases (CVDs) are the leading cause of mortality worldwide, highlighting the need for improved risk prediction and prevention strategies. Polygenic Risk Scores (PRS), derived from genome-wide as
