Cologne (Germany): Institute for Quality and Efficiency in Health Care (IQWiG); 2026 Feb 22.ABSTRACTRESEARCH QUESTION: The aim of this report is toassess the benefit of diagnostics using cardiac magnetic resonance imaging as part of a diagnostic strategy, compared with a diagnostic strategy without
Rheumatology (Oxford). 2026 Feb 14:keag088. doi: 10.1093/rheumatology/keag088. Online ahead of print.ABSTRACTWith new insights into damage accrual, new outcome measures and new therapies emerging, treatment for lupus nephritis (LN) has evolved over the last years. Although a greater proportion of pa
J Gerontol A Biol Sci Med Sci. 2026 Feb 15:glag035. doi: 10.1093/gerona/glag035. Online ahead of print.ABSTRACTBACKGROUND: Frailty has been increasingly recognized as a significant contributor to adverse cardiovascular outcomes. However, the metabolic mechanisms underlying this relationship remain u
J Gerontol A Biol Sci Med Sci. 2026 Feb 15:glag042. doi: 10.1093/gerona/glag042. Online ahead of print.ABSTRACTHeld on 17 August 2025 in Guangzhou, the inaugural International Exchange Forum of the Chinese Geriatrics Society marked a significant milestone in advancing geroscience and fostering globa
Diabet Med. 2026 Feb 15:e70250. doi: 10.1111/dme.70250. Online ahead of print.ABSTRACTAIMS: To evaluate the impact of diabetes on in-hospital outcomes among patients with metabolic dysfunction-associated steatotic liver disease (MASLD) who were hospitalized for cardiovascular disease (CVD).METHODS:
Am J Hypertens. 2026 Feb 15:hpag013. doi: 10.1093/ajh/hpag013. Online ahead of print.ABSTRACTBACKGROUND: Hypertension is a major risk factor for cardiovascular disease. Mobile health applications may contribute to the primary prevention of hypertension. This systematic review and meta-analysis evalu
Am J Hypertens. 2026 Feb 15:hpag011. doi: 10.1093/ajh/hpag011. Online ahead of print.ABSTRACTBACKGROUND: Hypertension and diabetes mellitus are both known risk factors for atrial fibrillation (AF). Whether coexisting hypertension exacerbates AF risk among individuals with diabetes remains unclear. T
Geroscience. 2026 Feb 16. doi: 10.1007/s11357-026-02143-9. Online ahead of print.ABSTRACTSirtuins (SIRT1-SIRT7) are NAD⁺-dependent regulators of mitochondrial metabolism, chromatin remodeling, and stress resilience pathways-processes that are central to both aging biology and breast cancer (BC) hete
Neurol Sci. 2026 Feb 16;47(3):264. doi: 10.1007/s10072-026-08875-y.ABSTRACTBACKGROUND: Mitochondrial disorders are a group of heterogeneous diseases marked by deficiencies in oxidative phosphorylation (OXPHOS). A common subtype, MELAS (mitochondrial encephalopathy, lactic acidosis, and stroke-like e
Signal Transduct Target Ther. 2026 Feb 16;11(1):55. doi: 10.1038/s41392-025-02357-x.ABSTRACTLipid metabolism is essential for maintaining cellular homeostasis, and its dysregulation is linked to various diseases, including cancer, cardiovascular disease, and diabetes. Immune cells, such as macrophag
No abstractSci Rep. 2026 Feb 15. doi: 10.1038/s41598-026-40037-0. Online ahead of print.NO ABSTRACTPMID:41692790 | DOI:10.1038/s41598-026-40037-0
BMC Med. 2026 Feb 16. doi: 10.1186/s12916-026-04701-6. Online ahead of print.ABSTRACTBACKGROUND: Cardiovascular disease (CVD) is a major global health burden, particularly among overweight and obese individuals. We aimed to investigate associations between different physical activity patterns (conce
J Clin Lipidol. 2026 Jan 23:S1933-2874(26)00016-4. doi: 10.1016/j.jacl.2026.01.014. Online ahead of print.ABSTRACTBACKGROUND: Heterozygous familial hypercholesterolemia (HeFH) is a common autosomal dominant disorder, and adults with HeFH can have other cardiometabolic risk factors that increase the
J Clin Lipidol. 2026 Jan 27:S1933-2874(26)00018-8. doi: 10.1016/j.jacl.2026.01.018. Online ahead of print.ABSTRACTBACKGROUND: Elevated lipoprotein(a) [Lp(a)] is an independent and causal risk factor for atherosclerotic cardiovascular disease. Increasingly, prevention societies recommend testing Lp(a
Clin Genitourin Cancer. 2026 Jan 22:102509. doi: 10.1016/j.clgc.2026.102509. Online ahead of print.ABSTRACTBACKGROUND: Among patients with adenocarcinoma of the urinary bladder (ADKUB), prognostic analysis of urachal ADKUB is relatively limited, and there is no unified staging system. To investigate
J Matern Fetal Neonatal Med. 2026 Dec;39(1):2625540. doi: 10.1080/14767058.2026.2625540. Epub 2026 Feb 15.ABSTRACTBACKGROUND: Functional pulmonary atresia (FPA) is a rare neonatal condition charac-terized by the failure of a structurally normal pulmonary valve to open.METHODS: This case series analy
Rev Infirm. 2026 Feb;75(318):26-27. doi: 10.1016/j.revinf.2025.12.026. Epub 2026 Feb 4.ABSTRACTCognitive sequelae following a stroke represent a clinical and social challenge. Post-stroke dementia results from complex interactions between brain damage and risk factors. Early assessment, prevention,
Rev Infirm. 2026 Feb;75(318):25. doi: 10.1016/j.revinf.2025.12.025. Epub 2026 Feb 4.ABSTRACTStroke also affects children, including young children.PMID:41692561 | DOI:10.1016/j.revinf.2025.12.025
Rev Infirm. 2026 Feb;75(318):17-18. doi: 10.1016/j.revinf.2025.12.021. Epub 2026 Feb 4.ABSTRACTEducating the general public, starting at school age, helps reduce mortality and the after-effects of stroke. The acronym FAST, which summarizes the signs of stroke, is something everyone should know.PMID:
Rev Infirm. 2026 Feb;75(318):14-16. doi: 10.1016/j.revinf.2025.12.020. Epub 2026 Feb 4.ABSTRACTA stroke is a medical emergency caused by a problem with blood flow to the brain. Strokes are a major public health issue due to their frequency and the disability they cause. They can lead to death or ser
BMJ Open. 2026 Feb 15;16(2):e107472. doi: 10.1136/bmjopen-2025-107472.ABSTRACTINTRODUCTION: Dyspnoea is an existentially burdensome symptom in patients with advanced and progressive diseases such as cancer, chronic obstructive pulmonary disease (COPD) and advanced heart failure. Recent studies have
BMJ Open. 2026 Feb 15;16(2):e107969. doi: 10.1136/bmjopen-2025-107969.ABSTRACTOBJECTIVES: To assess the incidence and risk of major adverse cardiovascular events (MACE) in patients with different stages of chronic kidney disease (CKD) and end-stage kidney disease (ESKD) in Taiwan.DESIGN: Retrospecti
BMJ Case Rep. 2026 Feb 15;19(2):e269479. doi: 10.1136/bcr-2025-269479.ABSTRACTWe report a case of a patient who developed delayed-onset, persisting autoimmune heparin-induced thrombocytopenia (HIT) following prophylactic anticoagulation with unfractionated heparin (UFH) after surgical treatment of a
Nihon Hoshasen Gijutsu Gakkai Zasshi. 2026;82(4). doi: 10.6009/jjrt.26-1579.ABSTRACTPURPOSE: We investigated flip angle (FA) and cerebrovascular imaging performance in three-dimensional time-of-flight magnetic resonance angiography (3D TOF-MRA) without using a venous signal saturation pulse in the d
