J Investig Med. 2026 Jul 24:10815589261473278. doi: 10.1177/10815589261473278. Online ahead of print.ABSTRACTBACKGROUND: Inflammatory bowel disease (IBD) is a chronic immune-mediated intestinal disorder characterized by recurrent inflammation. Growing research over the last ten years has connected i
J Investig Med. 2026 Jul 24:10815589261473287. doi: 10.1177/10815589261473287. Online ahead of print.ABSTRACTCardiovascular disease is the leading cause of death in women, who also experience worse outcomes after a cardiovascular event. Lifestyle factors such as diet, physical activity, and smoking
Circ Res. 2026 Jul 24. doi: 10.1161/CIRCRESAHA.126.328542. Online ahead of print.ABSTRACTBACKGROUND: Longitudinal metabolomic studies can refine understanding of heart failure (HF) progression and enable precision prevention. This study aims to identify serum metabolites associated with HF risk via
Circ Cardiovasc Interv. 2026 Jul 24:e016286. doi: 10.1161/CIRCINTERVENTIONS.125.016286. Online ahead of print.ABSTRACTBACKGROUND: Optimal treatment of coronary artery disease in patients undergoing transcatheter aortic valve implantation remains debated. Here, our aim was to analyze the impact of th
Circ Cardiovasc Imaging. 2026 Jul 24:e018658. doi: 10.1161/CIRCIMAGING.125.018658. Online ahead of print.ABSTRACTCardiovascular imaging plays a central role in the diagnosis, risk stratification, and longitudinal management of cardiovascular disease during pregnancy. Physiological adaptations-includ
Front Cell Dev Biol. 2026 Jul 9;14:1828772. doi: 10.3389/fcell.2026.1828772. eCollection 2026.ABSTRACTLow-density lipoprotein (LDL) receptor-related protein 6 (LRP6) is crucial for the canonical wingless signaling pathway and the clearance of LDL from the bloodstream. Genetic variants in the LRP6 ge
Front Immunol. 2026 Jul 9;17:1797028. doi: 10.3389/fimmu.2026.1797028. eCollection 2026.ABSTRACTBACKGROUND: Myocardial infarction (MI) remains a leading cause of cardiovascular mortality worldwide, underscoring the need for improved diagnostic and therapeutic strategies. Despite recent in clinical m
Front Immunol. 2026 Jul 9;17:1798798. doi: 10.3389/fimmu.2026.1798798. eCollection 2026.ABSTRACTMetabolic regulation and its underlying mechanisms play a critical role in controlling and resolving inflammation in the brain, directly shaping glial cell activation and the central nervous system's resp
Front Immunol. 2026 Jul 9;17:1901792. doi: 10.3389/fimmu.2026.1901792. eCollection 2026.ABSTRACTObstructive sleep apnea (OSA) is increasingly recognized as an independent contributor to atherosclerotic cardiovascular disease, yet the mechanisms linking nocturnal intermittent hypoxia (IH) to plaque p
Front Immunol. 2026 Jul 9;17:1882018. doi: 10.3389/fimmu.2026.1882018. eCollection 2026.ABSTRACTBACKGROUND: Chronic total occlusion (CTO) percutaneous coronary intervention (PCI) has improved outcomes, yet residual cardiovascular risk persists. The neutrophil percentage-to-albumin ratio (NPAR), an i
Front Netw Physiol. 2026 Jul 9;6:1865256. doi: 10.3389/fnetp.2026.1865256. eCollection 2026.ABSTRACTBACKGROUND: This companion empirical study established fundamental heterogeneity in pre-arrhythmic dynamical pathways across nine PhysioNet cohorts (N > 1,500 records): 93%-98% of events do not follow
Card Fail Rev. 2026 Jul 14;12:e17. doi: 10.15420/cfr.2025.51. eCollection 2026.ABSTRACTAcute heart failure (AHF) is a systemic condition characterised by multiorgan involvement that varies from subclinical to overt organ failure. The liver is particularly vulnerable due to its dual blood supply and
Photoacoustics. 2026 Jul 18;51:100857. doi: 10.1016/j.pacs.2026.100857. eCollection 2026 Oct.ABSTRACTElastin supports tissue elasticity and structural stability, but its regeneration is minimal in adulthood. Monitoring elastin remodeling is therefore important for understanding aging and related car
Cureus. 2026 Jun 23;18(6):e111338. doi: 10.7759/cureus.111338. eCollection 2026 Jun.ABSTRACTAnthracyclines remain central to the treatment of many malignancies, yet their use is limited by the risk of anthracycline-induced cardiomyopathy (AIC), a complication associated with substantial long-term ca
Cureus. 2026 Jun 23;18(6):e111377. doi: 10.7759/cureus.111377. eCollection 2026 Jun.ABSTRACTSecondary hyperparathyroidism (sHPT) is a prevalent complication of end-stage renal disease, driven by phosphate retention, vitamin D deficiency, hypocalcemia, and calcium-sensing receptor dysregulation. Desp
Cureus. 2026 Jun 22;18(6):e111322. doi: 10.7759/cureus.111322. eCollection 2026 Jun.ABSTRACTObesity and cardiovascular (CV) disease (CVD) are tightly intertwined global epidemics, with excess adiposity now recognized as a major, modifiable driver of atherosclerotic events, heart failure, and mortali
J Mol Cell Cardiol Plus. 2026 Jul 16;17:100856. doi: 10.1016/j.jmccpl.2026.100856. eCollection 2026 Sep.ABSTRACTMicroRNAs are non-coding RNA sequences capable of transport outside the cell to regulate essential cellular processes. They are able to induce structural changes implicated in prevalent ca
Vavilovskii Zhurnal Genet Selektsii. 2026 Jul;30(4):676-684. doi: 10.18699/vjgb-26-68.ABSTRACTThe multifactorial etiology of complex diseases involves the interplay of polygenic/oligogenic susceptibility loci and environmental factors. Complex diseases are characterized by pronounced phenotypic vari
EClinicalMedicine. 2026 Jul 18;98:104059. doi: 10.1016/j.eclinm.2026.104059. eCollection 2026 Aug.ABSTRACTBACKGROUND: In parallel with diagnostic advances and awareness of cardiac amyloidosis (CA) in aging populations, frailty is increasingly observed in CA. However, the relationship between the fra
Clin Med Insights Cardiol. 2026 Jul 22;20:11795468251396355. doi: 10.1177/11795468251396355. eCollection 2026.ABSTRACTOBJECTIVE: This study investigates gender disparities in clinical outcomes among patients with systemic sclerosis (SSc)-associated pulmonary arterial hypertension (PAH), focusing on
Front Cardiovasc Med. 2026 Jul 9;13:1839237. doi: 10.3389/fcvm.2026.1839237. eCollection 2026.ABSTRACTBACKGROUND: Reliable biomarkers for long-term risk stratification in coronary artery ectasia (CAE) remain limited. The systemic immune-inflammation index (SII), derived from routine hematological pa
Front Cardiovasc Med. 2026 Jul 9;13:1814149. doi: 10.3389/fcvm.2026.1814149. eCollection 2026.ABSTRACTBACKGROUND: Sarcopenia is common in patients with cardiovascular disease (CVD) and is associated with functional decline and adverse clinical outcomes. However, practical tools for early risk strati
Front Cardiovasc Med. 2026 Jul 9;13:1875972. doi: 10.3389/fcvm.2026.1875972. eCollection 2026.ABSTRACTBACKGROUND AND AIMS: In the face of escalating cardiovascular disease (CVD) prevalence, the demand for evidence-backed cardiac rehabilitation has surged, making it a guideline-recommended secondary
Front Cardiovasc Med. 2026 Jul 9;13:1821490. doi: 10.3389/fcvm.2026.1821490. eCollection 2026.ABSTRACTBACKGROUND: Atherosclerotic cardiovascular disease remains a major cause of morbidity and mortality worldwide, with residual cardiovascular risk persisting despite optimized lipid-lowering therapy.
