Paediatric proteomic signatures of cardiometabolic disease-associated traits predict adult disease outcomes

Nat Metab. 2026 Sep 11. doi: 10.1038/s42255-026-01589-7. Online ahead of print.ABSTRACTWhile the earliest pathological signs of cardiovascular-kidney-metabolic disease (CKMD) emerge before age 20, current adult-based risk thresholds fail to identify a substantial fraction of children at high risk. W

J Joshua M Landman

Low body mass index is not necessarily low cardiovascular risk in hypertension

No abstractHypertens Res. 2026 Sep 11. doi: 10.1038/s41440-026-02807-1. Online ahead of print.NO ABSTRACTPMID:42728329 | DOI:10.1038/s41440-026-02807-1

T Takashi Hisamatsu

Japanese Anticholinergic Risk Scale and Domain-Specific Functional Outcomes in Older Poststroke Patients

Geriatr Gerontol Int. 2026 Sep;26(9):e70842. doi: 10.1111/ggi.70842.ABSTRACTAIM: International anticholinergic burden scales may incompletely capture country-specific prescribing patterns and drug availability. Although the Japanese Anticholinergic Risk Scale (JARS) reflects Japanese clinical practi

A Ayaka Matsumoto

Severe Phenotype in an Indian Family With Progressive Pseudorheumatoid Arthropathy of Childhood

Am J Med Genet A. 2026 Sep 11. doi: 10.1002/ajmg.a.70233. Online ahead of print.ABSTRACTProgressive pseudorheumatoid arthropathy of childhood (PPAC) is a rare autosomal recessive progressive condition that affects the cartilage of joints and bones. The symptoms of PPAC include stiffness of the joint

N Narinder Singh

Maternal and Fetal HLA Heterozygosity in Preeclampsia: Insights From a Large Multi-Ancestry Pregnancy Cohort

HLA. 2026 Sep;108(3):e70970. doi: 10.1111/tan.70970.ABSTRACTPreeclampsia (PE) is a leading cause of maternal and neonatal morbidity, with immune dysregulation at the maternal-fetal interface central to its pathogenesis. The highly polymorphic HLA region mediates maternal immune tolerance of the semi

C Chang Cao

Between-visit Reproducibility of Cerebrovascular and Cardiovascular Reactivity During the Cold Pressor Test

Am J Physiol Heart Circ Physiol. 2026 Sep 11. doi: 10.1152/ajpheart.00226.2026. Online ahead of print.ABSTRACTThe cold pressor test (CPT) is a painful test used to assess cardiovascular and cerebrovascular reactivity. Past studies examined between-visit reproducibility of cardiovascular reactivity d

J Joseph D Vondrasek

Circulating Growth Hormone-Releasing Hormone Increases After Kidney Transplantation and Shows Divergent Associations with Gut-Derived Uremic Toxins

Eur J Intern Med. 2026 Sep 11:107178. doi: 10.1016/j.ejim.2026.107178. Online ahead of print.ABSTRACTBACKGROUND: The growth hormone/insulin-like growth factor-1 (GH/IGF-1) axis is disrupted in chronic kidney disease (CKD), yet its upstream regulator, growth hormone-releasing hormone (GHRH), has neve

C Camillo Tancredi Strizzi

Deubiquitinases in mitophagy: therapeutic control of mitochondrial quality

Trends Pharmacol Sci. 2026 Sep 12:S0165-6147(26)00206-3. doi: 10.1016/j.tips.2026.08.009. Online ahead of print.ABSTRACTMitochondrial quality control is essential for maintaining cellular and tissue homeostasis. Mitophagy, the selective autophagic removal of damaged mitochondria, is a central compon

Y Yang Xu

Gastric bypass and sleeve gastrectomy: Impact on cardiovascular risk factors

Clin Investig Arterioscler. 2026 Sep 11:500962. doi: 10.1016/j.arteri.2026.500962. Online ahead of print.ABSTRACTMetabolic bariatric surgery has become the most effective intervention for severe obesity and its associated diseases. Among the available techniques, Roux-en-Y gastric bypass (RYGB) and

D David Benaiges

Temporal aspects and implications of the measurement of lipoprotein(a) in patients with acute myocardial infarction

J Clin Lipidol. 2026 Aug 29:S1933-2874(26)00485-X. doi: 10.1016/j.jacl.2026.08.011. Online ahead of print.ABSTRACTBACKGROUND: Lipoprotein(a) [Lp(a)] is a genetically mediated, causal risk factor for atherosclerotic cardiovascular disease.OBJECTIVE: We examined Lp(a) changes during and after acute my

S Seyed Saeed Tamehri Zadeh

A 20% increase in circulating Lp(a) after the commencement of statins, and subsequent risks of atherosclerotic cardiovascular diseases in patients with coronary artery disease

J Clin Lipidol. 2026 Aug 23:S1933-2874(26)00484-8. doi: 10.1016/j.jacl.2026.08.010. Online ahead of print.ABSTRACTBACKGROUND: Lipoprotein(a) [Lp(a)] is an independent and causal risk factor for atherosclerotic cardiovascular disease. While Lp(a) levels are genetically determined and stable, statins

S Shuhei Fujita

Lipoprotein(a) and subclinical atherosclerosis

J Clin Lipidol. 2026 Sep 2:S1933-2874(26)00497-6. doi: 10.1016/j.jacl.2026.08.025. Online ahead of print.ABSTRACTBACKGROUND: Lipoprotein(a) [Lp(a)] is a causal risk factor for atherosclerotic cardiovascular disease.SOURCES OF MATERIAL: Literature review.ABSTRACT OF FINDINGS: A large body of evidence

A Apurva Khedagi

Multidisciplinary management of an older adult with vascular Ehlers-Danlos syndrome and multiple autoimmune comorbidities

BMJ Case Rep. 2026 Sep 11;19(9):e274392. doi: 10.1136/bcr-2026-274392.ABSTRACTVascular Ehlers-Danlos syndrome (vEDS) is a rare connective tissue disorder characterised by vascular fragility and risk of arterial complications. Further overlap with autoimmune diseases and multisystem comorbidities cre

A Ali Burianek

Subarachnoid haemorrhage associated with septic cavernous sinus thrombosis secondary to odontogenic maxillary sinusitis

BMJ Case Rep. 2026 Sep 11;19(9):e271999. doi: 10.1136/bcr-2026-271999.ABSTRACTThis case report describes a man in his 50 s who developed septic cavernous sinus thrombosis secondary to odontogenic maxillary sinusitis complicated by a non-aneurysmal subarachnoid haemorrhage (SAH). He presented with vi

Y Yoshiyuki Nagamine

Acute psychosis unmasking severe non-ischaemic cardiomyopathy with biventricular thrombosis and cardioembolic cerebral infarcts

BMJ Case Rep. 2026 Sep 11;19(9):e274214. doi: 10.1136/bcr-2026-274214.ABSTRACTA woman in her early 30s with major depressive disorder and generalised anxiety disorder presented with a 3- to 4-week history of progressive paranoia, auditory hallucinations and behavioural disorganisation, initially adm

B Bushra Elhusein

Intraosseous venous malformation of the clivus

BMJ Case Rep. 2026 Sep 11;19(9):e268579. doi: 10.1136/bcr-2025-268579.ABSTRACTThis case report presents a female patient in her teens who experienced a 1-month history of intermittent right-sided tongue numbness and twitching.Investigations included laboratory tests and an electroencephalogram, both

A Adebayo Olusola Alade

Uterine arteriovenous malformation: conservative approach in its management

BMJ Case Rep. 2026 Sep 11;19(9):e273671. doi: 10.1136/bcr-2026-273671.ABSTRACTUterine arteriovenous malformations (UAVM) are diagnosed more commonly in modern times due to increasing surgical interventions, abortions and better diagnostic modalities. They pose the risk of life-threatening morbidity

I Indrani Mukhopadhyay

Lymphatics-epicardial cross talk via Reelin controls cardiac growth

Genes Dev. 2026 Sep 11. doi: 10.1101/gad.354151.126. Online ahead of print.ABSTRACTHow mammalian organ size is precisely regulated remains incompletely understood. This process depends on the coordinated balance between cell proliferation, differentiation, and apoptosis. In the heart, the epicardium

Y Yalu Zhou

How can critical actors be incentivised to take a systems approach to pursue preventative public health?

Evid Policy. 2026 Sep 10:1-25. doi: 10.1332/17442648Y2026D000000107. Online ahead of print.ABSTRACTINTRODUCTION: In this article we explore how critical actors can be incentivised to take a systems approach to pursue preventative public health. More specifically, we focus on the link between urban e

A Andrew Barnfield

Simultaneous derivation, validation, and comparison of predictor hazard ratios for cardiovascular risk prediction equations in patients with diabetes from high versus non-high income countries: cohort study

BMJ. 2026 Sep 11;394:e100535. doi: 10.1136/bmj-2026-100535.ABSTRACTOBJECTIVE: To directly test the generalisability of cardiovascular disease (CVD) risk predictor effects across populations in a high income versus non-high income country, derive comparable risk equations, and identify more effective

J Jingyuan Liang

Author Corrections to: "Canadian Cardiovascular Society 2022 Guidelines for Cardiovascular Interventions in Adults With Congenital Heart Disease [Canadian Journal of Cardiology 38 (2022), 862-896]"

No abstractCan J Cardiol. 2026 Sep 11:S0828-282X(26)01176-1. doi: 10.1016/j.cjca.2026.08.014. Online ahead of print.NO ABSTRACTPMID:42727929 | DOI:10.1016/j.cjca.2026.08.014

A Ariane Marelli

Where the Future Lies: GLP-1 Receptor Agonists as Therapeutics for Dermatologic Comorbidities

Clin Dermatol. 2026 Sep 11:S0738-081X(26)00229-4. doi: 10.1016/j.clindermatol.2026.09.003. Online ahead of print.ABSTRACTGlucagon-like peptide-1 receptor agonists (GLP-1RAs) have transformed the management of obesity, type 2 diabetes mellitus, and cardiometabolic disease through effects on weight re

M Mikaela DeCoster

Molecular Rejection Signatures in Pancreas Transplant Biopsies

Am J Transplant. 2026 Sep 11:S1600-6135(26)02758-9. doi: 10.1016/j.ajt.2026.09.015. Online ahead of print.ABSTRACTPancreas allograft rejection remains a key contributor to graft failure, yet its diagnosis relies on histological criteria. In this study, we applied the Molecular Microscope® Diagnostic

E Eva Girmanova

F-actin-dependent activation of NADPH oxidase 5 by the vacuolar-type ATPase

J Biol Chem. 2026 Sep 11:113546. doi: 10.1016/j.jbc.2026.113546. Online ahead of print.ABSTRACTNADPH oxidase 5 (NOX5) is a transmembrane oxidative signaling enzyme that produces superoxide in response to increases in intracellular calcium. NOX5 has been shown to play essential roles in processes suc

G Gwen J Heywood