Assessing frailty in hemodialysis patients: utility of a self-rated visual analogue scale and the role of routine parameters in clinical prediction

BMC Nephrol. 2026 Jul 22;27(1):443. doi: 10.1186/s12882-026-05218-z.ABSTRACTBACKGROUND: There is still no established consensus on the optimal frailty screening tool for routine clinical application in patients with chronic kidney disease (CKD). We evaluated the accuracy of a visual analogue scale (

L Lena Schulte-Kemna

Mol2Image: an enhanced DDI prediction framework leveraging drug molecular descriptors

BMC Bioinformatics. 2026 Jul 22;27(1):159. doi: 10.1186/s12859-026-06552-7.ABSTRACTDrug-drug interactions (DDIs) are a critical safety issue in clinical practice, as they can lead to severe and often unpredictable adverse effects. This risk becomes significantly higher in multi-drug therapies, which

N Nourhan Helmy

Hypertension and gut microbial hydrogenases: a comparison of hydrogen metabolism and etiology

Med Gas Res. 2026 Dec 1;16(4):352-358. doi: 10.4103/mgr.MEDGASRES-D-25-00128. Epub 2026 Jul 23.ABSTRACTJOURNAL/mgres/04.03/01612956-202612000-00006/figure1/v/2026-07-23T200825Z/r/image-tiff Hypertension is a prevalent chronic condition and serves as a significant risk factor for numerous cardiovascu

Y Yang Yi

Prevalence of Risk Factors and Awareness of University Students regarding Hypertension and Cardiovascular Diseases in Riyadh, Saudi Arabia

J Community Health. 2026 Jul 23. doi: 10.1007/s10900-026-01616-4. Online ahead of print.ABSTRACTHypertension is a major global health issue, posing the highest risk for CVD-related deaths. WHO reports that hypertension prevalence increased from 650 million in 1990 to 1.4 billion in 2024. Once rare i

M Mona A Alfadeel

The association of social isolation and family structure on stroke-specific quality of life in a community-based study

Qual Life Res. 2026 Jul 23;35(9):233. doi: 10.1007/s11136-026-04337-2.ABSTRACTPURPOSE: Quality of Life (QOL) is a critical patient-centered outcome for individuals who have experienced stroke. This study examined the association of social isolation and family structure with Stroke-Specific QOL (SSQO

J Josh Martins-Caulfield

Broad-coverage targeted lipidomics reveals stage-specific lipid metabolic profiles and diagnostic and prognostic marker panels in ischemic stroke

Metabolomics. 2026 Jul 23;22(4):132. doi: 10.1007/s11306-026-02485-7.ABSTRACTBACKGROUND: Ischemic stroke (IS) is a major cause of mortality and disability globally, with challenges in early diagnosis and prognosis prediction. Dysregulated lipid metabolism is key to IS pathophysiology, but comprehens

H Haoran Huang

Dyspnea in heart failure: pathophysiology, clinical assessment, and evidence from clinical trials

Heart Fail Rev. 2026 Jul 24;31(1):88. doi: 10.1007/s10741-026-10659-7.ABSTRACTDyspnea is a key symptom of heart failure (HF), particularly in its acute form, where it represents the most common cause of hospitalization. Although traditionally attributed to pulmonary congestion, dyspnea in HF is a mu

M Mateusz Garus

A sex-specific perspective on coronary microvascular dysfunction in HFpEF: from vascular to myocardial disease

Heart Fail Rev. 2026 Jul 24;31(1):87. doi: 10.1007/s10741-026-10661-z.ABSTRACTHeart failure with preserved ejection fraction (HFpEF) is the most prevalent form of heart failure and is characterized by high morbidity, limited therapeutic options, and marked biological heterogeneity. Coronary microvas

A Anne-Sophie Roy

The cardiac 4D nucleome: nuclear and chromatin dynamics across development, disease and ageing

Nat Rev Cardiol. 2026 Jul 23. doi: 10.1038/s41569-026-01322-7. Online ahead of print.ABSTRACTThe nucleus is a highly organized and dynamic organelle, with hierarchical layers ranging from nucleosome positioning to chromatin domains and higher-order 3D genome topology. Viewed over time as the 4D nucl

Y Yinuo Wang

Gut microbiome composition differs between aortic stenosis and aortic regurgitation patients

Sci Rep. 2026 Jul 23;16(1):23073. doi: 10.1038/s41598-026-63354-w.ABSTRACTThe gut microbiome has emerged as an important modulator of cardiovascular diseases, yet data on aortic valve disorders, particularly aortic stenosis (AS), remain limited. This study aimed to characterize gut microbiome differ

B Benedikt Bartsch

Clinicopathological features and prognostic factors associated with long-term survival (≥5 years) in patients with clear cell renal cell carcinoma and venous tumor thrombus

Beijing Da Xue Xue Bao Yi Xue Ban. 2026 Aug 18;58(4):692-699.ABSTRACTOBJECTIVE: To characterize the clinicopathological features of long-term survivors among patients with clear cell renal cell carcinoma (ccRCC) and venous tumor thrombus (VTT) who underwent surgical treatment, and to explore potenti

Z Zhiming DU

Combined triglyceride-glucose index and body mass index for early cardiovascular risk stratification in adults under 45: Findings from the Kailuan cohort

Nutr Metab Cardiovasc Dis. 2026 Jul 23:104865. doi: 10.1016/j.numecd.2026.104865. Online ahead of print.ABSTRACTBACKGROUND AND AIM: Early-onset cardiovascular disease (CVD) in adults aged<45 years represents an increasing global health challenge. We aimed to evaluate the potential effects of the tri

S Shuaiya Wang

Two cases of late-onset lysosomal acid lipase deficiency with Achilles tendon thickening

J Clin Lipidol. 2026 Jul 8:S1933-2874(26)00430-7. doi: 10.1016/j.jacl.2026.07.002. Online ahead of print.ABSTRACTLysosomal acid lipase deficiency (LAL-D) is a rare autosomal recessive lysosomal storage disease, classified into early-onset form and late-onset form. Late-onset LAL-D is characterized b

M Masahito Michikura

Projected impact of 2026 ACC/AHA/Multisociety Dyslipidemia Guideline on lipid-lowering therapy eligibility based on Class 1 and 2a recommendations

J Clin Lipidol. 2026 Jul 10:S1933-2874(26)00434-4. doi: 10.1016/j.jacl.2026.07.008. Online ahead of print.ABSTRACTBACKGROUND: The 2026 American College of Cardiology/American Heart Association/Multisociety Dyslipidemia Guideline introduced pivotal changes to lipid-lowering therapy (LLT) eligibility

S Sameer A Sidiq

Effect of Treatment Timing on Voice Outcomes After Intracordal Trafermin Injection for Vocal Fold Paralysis Following Aortic Surgery

J Voice. 2026 Jul 23:S0892-1997(26)00366-8. doi: 10.1016/j.jvoice.2026.07.014. Online ahead of print.ABSTRACTOBJECTIVE: We aimed to investigate the relationship between the timing of intracordal trafermin injection (ITI) and subsequent voice improvement in patients with unilateral vocal fold paralys

M Mariko Terasaki

Rising burden of Alzheimer's mortality linked to hypertension: A U.S. population-based study, 1999-2023

J Natl Med Assoc. 2026 Jul 3:S0027-9684(26)00120-3. doi: 10.1016/j.jnma.2026.06.020. Online ahead of print.ABSTRACTBACKGROUND: Hypertension (HTN) remains a key contributor to adverse outcomes in older adults with Alzheimer's disease (AD), which itself is the seventh leading cause of death in the U.S

M Muhammad Shaheer Bin Faheem

Toward a CKLM framework for integrated clinical trial design

No abstractGut. 2026 Jul 23:gutjnl-2026-340045. doi: 10.1136/gutjnl-2026-340045. Online ahead of print.NO ABSTRACTPMID:42493233 | DOI:10.1136/gutjnl-2026-340045

X Xiao-Dong Zhou

Association of rhinocerebral mucormycosis and granulomatosis with polyangiitis (Wegener's granulomatosis)

BMJ Case Rep. 2026 Jul 23;19(7):e266390. doi: 10.1136/bcr-2025-266390.ABSTRACTRhinocerebral mucormycosis is a rare but life-threatening fungal infection that predominantly affects immunocompromised individuals. We describe the case of a man in his mid-60s with a history of rheumatoid arthritis, diab

O Omer Esmez

Abdominal aortic aneurysm and renal cell carcinoma in the presence of crossed fused renal ectopia

BMJ Case Rep. 2026 Jul 23;19(7):e272555. doi: 10.1136/bcr-2026-272555.ABSTRACTAbdominal aortic aneurysms, renal cell carcinomas and crossed fused renal ectopias are significant conditions within the fields of vascular and urological surgery. The simultaneous occurrence of all three is exceptionally

C Chloé Moran

Recurrent embolic cerebellar infarction due to bow hunter's syndrome of the non-dominant vertebral artery

BMJ Case Rep. 2026 Jul 23;19(7):e272451. doi: 10.1136/bcr-2026-272451.ABSTRACTWe describe a rare presentation of bow hunter's syndrome (BHS) involving the non-dominant vertebral artery (VA), leading to recurrent embolic cerebellar infarction. A male in his mid-70s presented with sudden-onset immobil

H Hakim Baazaoui

Association between liver fibrosis severity and impaired myocardial glucose metabolism in subjects with different degrees of glucose tolerance

BMJ Open Diabetes Res Care. 2026 Jul 23;14(4):e006005. doi: 10.1136/bmjdrc-2026-006005.ABSTRACTINTRODUCTION: Increasing evidence suggests that liver fibrosis is an independent risk factor for cardiovascular disease. However, the mechanisms underlying this increased risk are still unsettled. The aim

E Elena Succurro

Effect of pictorial-based information about atherosclerosis on adherence to lifestyle recommendations: results from the VIPVIZA randomised controlled trial

Open Heart. 2026 Jul 23;13(2):e004136. doi: 10.1136/openhrt-2026-004136.ABSTRACTAIM: Low adherence to a healthy lifestyle constitutes a major barrier to effective prevention of cardiovascular disease. We aimed to investigate the effect of pictorial-based information about subclinical atherosclerosis

A Andree Christian Wennstig

Development and validation of a nomogram predicting all-cause mortality for patients with an implantable cardioverter defibrillator

Open Heart. 2026 Jul 23;13(2):e003966. doi: 10.1136/openhrt-2026-003966.ABSTRACTBACKGROUND: For patients with a high risk of sudden cardiac death, despite the benefits of an implantable cardioverter defibrillator (ICD), some patients are still at high risk of death.AIM: The purpose of this study was

B Bin Zhou

Endovascular treatment of type B aortic dissection in patients with and without end-stage renal disease: A propensity-matched cohort study

No abstractCurr Probl Surg. 2026 Aug;81:102069. doi: 10.1016/j.cpsurg.2026.102069. Epub 2026 May 26.NO ABSTRACTPMID:42493184 | DOI:10.1016/j.cpsurg.2026.102069

X Xiong Zhang