Pediatr Int. 2026 Jan-Dec;68(1):e70492. doi: 10.1111/ped.70492.ABSTRACTBACKGROUND: Early diagnosis of acute myocarditis (AMC) is crucial due to its rapid progression and high mortality rate. Initial symptoms such as fever, abdominal pain, and vomiting are nonspecific and pose challenges for clinicia
Cell Biochem Funct. 2026 Jul;44(7):e70264. doi: 10.1002/cbf.70264.ABSTRACTFerroptosis is a regulated form of cell death in which disturbed iron metabolism, accumulation of peroxidized membrane lipids, and insufficient glutathione peroxidase 4 (GPX4) activity converge to injure vascular cells. In ath
Clin Physiol Funct Imaging. 2026 Jul;46(4):e70084. doi: 10.1111/cpf.70084.ABSTRACTOBJECTIVE: To evaluate the effect of 12-week Mavacamten on left ventricular function in obstructive hypertrophic cardiomyopathy (oHCM) using myocardial work analysis, and explore its role in myocardial energy metabolis
Immun Inflamm Dis. 2026 Jul;14(7):e70489. doi: 10.1002/iid3.70489.ABSTRACTBACKGROUND: Whether Takayasu arteritis (TAK) and giant cell arteritis (GCA), the most common forms of large-vessel vasculitis (LVV), are distinct clinical entities or different manifestations of the same disease is an ongoing
Hypertension. 2026 Jul 27. doi: 10.1161/HYPERTENSIONAHA.126.26711. Online ahead of print.ABSTRACTBACKGROUND: Pulmonary arterial hypertension is a progressive and life-threatening disorder characterized by elevated pulmonary arterial pressure, right ventricular hypertrophy, and eventual right heart f
Hypertension. 2026 Jul 27. doi: 10.1161/HYPERTENSIONAHA.126.26793. Online ahead of print.ABSTRACTBACKGROUND: Hypertension remains the leading global contributor to cardiovascular mortality. Although renal denervation (RDN) has demonstrated efficacy, the central neurobiological mechanisms sustaining
J Biochem Mol Toxicol. 2026 Aug;40(8):e71033. doi: 10.1002/jbt.71033.ABSTRACTCardiac lipid metabolism is fundamental to myocardial energy homeostasis, with fatty acid oxidation (FAO) supplying the majority of ATP in the healthy adult heart. This review synthesizes the core regulatory network governi
Ann Noninvasive Electrocardiol. 2026 Jul;31(4):e70209. doi: 10.1111/anec.70209.ABSTRACTComplete atrioventricular block after mechanical tricuspid valve replacement represents a challenging pacing scenario because transvalvular right ventricular lead placement is contraindicated. We report a 51-year-
Mol Nutr Food Res. 2026 Jul;70(14):e70563. doi: 10.1002/mnfr.70563.ABSTRACTAspartame is a commonly used sweetener that is increasingly becoming the main source of sweetness in foods due to its low-calorie and high-sweetness characteristics. Excessive intake of aspartame can lead to the occurrence of
ACS Biomater Sci Eng. 2026 Jul 25. doi: 10.1021/acsbiomaterials.6c00565. Online ahead of print.ABSTRACTTrimethylamine N-oxide (TMAO) has recently emerged as a clinically relevant biomarker for the early diagnosis and risk stratification of chronic diabetic nephropathy and cardiovascular disease. Her
Cureus. 2026 Jun 26;18(6):e111529. doi: 10.7759/cureus.111529. eCollection 2026 Jun.ABSTRACTHeat stroke is a life-threatening medical emergency characterised by severe hyperthermia and central nervous system dysfunction. Cardiac manifestations, including troponin elevation and electrocardiographic a
Hosp Pharm. 2026 Jul 25:00185787261465850. doi: 10.1177/00185787261465850. Online ahead of print.ABSTRACTChronic Obstructive Pulmonary Disease (COPD) stands as a leading cause of death globally, with AECOPD significantly worsening patient outcomes. The intersection of COPD with CVDs further escalate
J Blood Med. 2026 Jul 22;17:626464. doi: 10.2147/JBM.S626464. eCollection 2026.ABSTRACTPURPOSE: To evaluate treatment and disease burden among patients with polycythemia vera (PV) receiving the current standard of care (SoC) in the US.PATIENTS AND METHODS: This retrospective study utilized MarketSca
PeerJ. 2026 Jul 23;14:e21531. doi: 10.7717/peerj.21531. eCollection 2026.ABSTRACTBACKGROUND: The incidence of distal femur fractures (DFF) has shown a continuous annual increase. Preoperative deep vein thrombosis (DVT) of the lower limbs in DFF patients is associated with unfavorable clinical outcom
Health Sci Rep. 2026 Jul 25;9(8):e72856. doi: 10.1002/hsr2.72856. eCollection 2026 Aug.ABSTRACTBACKGROUND: In South and Southeast Asia, chronic diseases (CD) are a major public health concern and have a considerable impact on people's quality of life (QoL). CD and their ailments place a dual burden
Health Sci Rep. 2026 Jul 25;9(8):e72841. doi: 10.1002/hsr2.72841. eCollection 2026 Aug.ABSTRACTBACKGROUND AND AIMS: Recent advancements in gene expression studies have shed light on the role of non-coding RNAs in negatively regulating mRNA and inhibiting mRNA translation. Given the significant impac
Health Sci Rep. 2026 Jul 25;9(8):e72875. doi: 10.1002/hsr2.72875. eCollection 2026 Aug.ABSTRACTBACKGROUND AND AIMS: The traditional definition of dyslipidemia focuses on isolated lipid changes (LDL-C, HDL-C, triglycerides) and may not fully capture the biological complexity or clinical variability o
Health Sci Rep. 2026 Jul 25;9(8):e72886. doi: 10.1002/hsr2.72886. eCollection 2026 Aug.ABSTRACTBACKGROUND: Ischemic heart disease (IHD) remains a leading cause of mortality and disability worldwide. Using Global Burden of Disease (GBD) 2021 estimates, this study provides an integrated assessment of
Drug Des Devel Ther. 2026 Jul 22;20:597886. doi: 10.2147/DDDT.S597886. eCollection 2026.ABSTRACTAlzheimer's disease (AD) poses a growing threat to global health, with no disease-modifying therapies currently available to cure or reverse its progression. Given its favorable safety profile and multi-t
Ann Med. 2026 Dec;58(1):2706870. doi: 10.1080/07853890.2026.2706870. Epub 2026 Jul 27.ABSTRACTBACKGROUND: Ischemic stroke (IS) remains a major cause of mortality and disability worldwide, although the causes of death after stroke have changed. Long-term mortality data from low- and middle-income cou
J Clin Endocrinol Metab. 2026 Jul 27:dgag292. doi: 10.1210/clinem/dgag292. Online ahead of print.ABSTRACTLow-renin hypertension is increasingly recognized as a common and clinically important form of hypertension. Expanded screening for primary aldosteronism has revealed many individuals with suppre
Mediators Inflamm. 2026;2026(1):e9984409. doi: 10.1155/mi/9984409.ABSTRACTBACKGROUND: Cardiovascular-kidney-metabolic (CKM) Stage 4 is defined by established cardiovascular disease in the setting of kidney and/or metabolic dysfunction. Despite the high risk carried by this condition, simple tools fo
Mediators Inflamm. 2026;2026(1):e1377824. doi: 10.1155/mi/1377824.ABSTRACTBACKGROUND: Psoriasis (PSO) and atherosclerosis (AS) are chronic inflammatory diseases that frequently coexist, with each condition exacerbating the other. However, the underlying mechanisms remain poorly understood, partly du
Ann Med. 2026 Dec;58(1):2703887. doi: 10.1080/07853890.2026.2703887. Epub 2026 Jul 26.ABSTRACTBACKGROUND: Pregnancy is regarded as a crucial window period for the assessment and management of cardiovascular health (CVH). This study investigated the relationship between the gestational CVH metrics of
