Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)-Based Genome Editing in Inherited Cardiovascular Diseases: Therapeutic Advances, Emerging Editing Platforms, and Translational Challenges

Cureus. 2026 Sep 11;18(9):e116111. doi: 10.7759/cureus.116111. eCollection 2026 Sep.ABSTRACTInherited cardiovascular diseases (ICVDs) are a broad category of hereditary disorders resulting from pathogenic mutations that alter cardiac anatomy, electrical conduction, and metabolic pathways. The main t

T Tosin Fakiyesi

Association Between Aerobic Physical Activity and Hypertension Among U.S. Adults: A Cross-Sectional Analysis of NHANES (National Health and Nutrition Examination Survey) 2021-2023

Cureus. 2026 Sep 11;18(9):e116112. doi: 10.7759/cureus.116112. eCollection 2026 Sep.ABSTRACTBackground Hypertension continues to be a principal modifiable risk factor for cardiovascular disease and premature mortality in the United States. Current clinical guidelines recommend regular aerobic physic

D Dylon J Wetzel

Towards a regional and national cardiothoracic biobank in India: translating a Dutch model to address a poorly characterised disease burden

Lancet Reg Health Southeast Asia. 2026 Sep 10;53:100860. doi: 10.1016/j.lansea.2026.100860. eCollection 2026 Oct.ABSTRACTCardiothoracic disease in India presents earlier and against a different biological background than in the high-income populations from which most evidence and guidelines derive.

N Nimrat Grewal

An urgent call for quality measures for cardiac implantable electronic device infections in the United States

Am Heart J Plus. 2026 Aug 22;70:100867. doi: 10.1016/j.ahjo.2026.100867. eCollection 2026 Oct.ABSTRACTInfection is a significant cause of morbidity and mortality among patients with cardiac implantable electronic devices (CIEDs). Over 400,000 CIEDs are placed annually in the United States with an in

S Sami El-Dalati

Cardiovascular and comorbid risk factors for thrombosis in primary immune thrombocytopenia: a single-center retrospective study

Res Pract Thromb Haemost. 2026 Sep 3;10(6):106940. doi: 10.1016/j.rpth.2026.106940. eCollection 2026 Aug.ABSTRACTBACKGROUND: There is evidence that patients with immune thrombocytopenia (ITP) are at increased risk of thrombosis. The associations of clinical and comorbid factors with thrombosis in IT

P Ping Zhang

Contribution of short-term changes in a composite health score on pathways linking social disadvantage and health: evidence from the UK biobank prospective cohort study

EClinicalMedicine. 2026 Sep 29;100:104221. doi: 10.1016/j.eclinm.2026.104221. eCollection 2026 Oct.ABSTRACTBACKGROUND: Chronic and repeated exposure to external stresses may be embodied and generate an adverse biological response, in-turn affecting health. We investigated the role of 4-year change i

H Helene Colineaux

Real-world cardiovascular risk estimation, blood pressure and LDL-cholesterol control: Two epidemiological studies in Romania, during pandemic and post-pandemic (SNAPSHOT-Romania)

Atheroscler Plus. 2026 Jun 18;66:100573. doi: 10.1016/j.athplu.2026.100573. eCollection 2026 Dec.ABSTRACTBACKGROUND AND AIMS: Data on estimation of cardiovascular (CV) risk by physicians and perceptions of hypertension and dyslipidemia control are lacking in Eastern Europe. Therefore, in patients wi

A Andrea Olivia Ciobanu

The association between albuminuria and coronary atherosclerotic burden in the general population

Atheroscler Plus. 2026 Sep 21;66:100610. doi: 10.1016/j.athplu.2026.100610. eCollection 2026 Dec.ABSTRACTBACKGROUND: Albuminuria predicts cardiovascular events, but its association with prevalent subclinical coronary atherosclerosis is less well defined. We examined the cross-sectional relationship

F Fredrik Bäckström Pegelow

Closing the Gaps in Heart Failure Care: A Call for a National Strategy in Canada

CJC Open. 2026 Jul 8;8(10):1343-1354. doi: 10.1016/j.cjco.2026.07.002. eCollection 2026 Oct.ABSTRACTHeart failure (HF) is a growing public health challenge in Canada, affecting over 787,000 individuals and contributing substantially to morbidity, mortality, and health care costs. Despite advances in

S Stephanie Poon

Effect of statins on the mortality of long-term survivors of nasopharyngeal carcinoma: a population-based study in endemic area

Lancet Reg Health West Pac. 2026 Sep 30;75:101993. doi: 10.1016/j.lanwpc.2026.101993. eCollection 2026 Oct.ABSTRACTBACKGROUND: Long-term survivors of nasopharyngeal cancer (NPC) are at risk of excessive mortality. This territory-wide cohort study aims to investigate the relationship between statin u

R Ru-Yu Xu

Time for Change: Strengthening Early Detection and Intervention Strategies to Improve Cardiovascular Health in Canada

CJC Open. 2026 May 12;8(10):1483-1494. doi: 10.1016/j.cjco.2026.05.002. eCollection 2026 Oct.ABSTRACTCardiovascular disease remains a significant cause of morbidity and mortality in Canada, and early detection and intervention programs have the potential to improve outcomes for patients. This review

A Andriy Katyukha

Adipocytokines as Pathogenic Mediators and Therapeutic Targets in Metabolic Syndrome-Related Cardiocerebrovascular Events

Diabetes Metab Syndr Obes. 2026 Oct 7;19:627279. doi: 10.2147/DMSO.S627279. eCollection 2026.ABSTRACTMetabolic syndrome (MS), characterized by central obesity, hyperglycemia, hypertension, and dyslipidemia, substantially increases the risk of cardiovascular and cerebrovascular events. Adipose tissue

Y Yue Wu

Prediction of patient-specific quality assurance for volumetric modulated arc therapy using machine log files

Quant Imaging Med Surg. 2026 Oct 1;16(10):763. doi: 10.21037/qims-2026-0916. Epub 2026 Aug 30.ABSTRACTBACKGROUND: Deep learning (DL) models have been used for predicting gamma passing rates (GPRs) of patient specific quality assurance (PSQA) in volumetric modulated arc therapy (VMAT). As the model i

Y Yuhan Fan

Blood lead exposure, renal hyperfiltration, and accelerated kidney function decline among people living with HIV in northern Tanzania: A longitudinal cohort study

Toxicol Rep. 2026 Sep 25;17:102348. doi: 10.1016/j.toxrep.2026.102348. eCollection 2026 Dec.ABSTRACTINTRODUCTION: People living with HIV (PLWH) face a high burden of kidney disease from HIV-related injury, antiretroviral toxicity, and environmental lead exposure. Renal hyperfiltration, an early comp

E Elias Charles Nyanza

Physical activity attenuates mortality risk associated with elevated resting heart rate in chronic kidney disease

iScience. 2026 Sep 30;29(10):117648. doi: 10.1016/j.isci.2026.117648. eCollection 2026 Oct 16.ABSTRACTThe independent and combined associations of resting heart rate (RHR) and physical activity (PA) with mortality in diverse chronic kidney disease (CKD) populations remain unclear. We analyzed 12,042

Y Ya Zhan

When the Heart Reveals Lupus: Severe Dilated Cardiomyopathy as the Initial Manifestation of Systemic Lupus Erythematosus

Cureus. 2026 Sep 11;18(9):e116094. doi: 10.7759/cureus.116094. eCollection 2026 Sep.ABSTRACTSystemic lupus erythematosus (SLE) is a multisystem autoimmune disease with heterogeneous cardiovascular involvement, while clinically overt lupus myocarditis remains uncommon. We report the case of a 50-year

M Mohamed Malki

Meta-analysis of the histopathological features of surgically removed aortas classified according to the SCVP and AECVP consensus documents

Am Heart J Plus. 2026 Sep 25;71:100904. doi: 10.1016/j.ahjo.2026.100904. eCollection 2026 Nov.ABSTRACTThe Society for Cardiovascular Pathology (SCVP) and the Association for European Cardiovascular Pathology (AECVP) published consensus statements on the surgical pathology of the aorta to unify nomen

E Eemeli Jämsen

Prognostic Impact of a Simple GDMT Score on Clinical Outcomes and Cardiac Reverse Remodelling in Patients with ADHF: Insights from the JROADHF-Next Registry

CJC Open. 2026 Jul 20;8(10):1310-1323. doi: 10.1016/j.cjco.2026.06.022. eCollection 2026 Oct.ABSTRACTBACKGROUND: Reported results indicate that implementation rates of guideline-directed medical therapy (GDMT) are associated with improved prognosis and cardiac function in heart failure (HF) patients

R Ryuichi Matsukawa

Frailty and Bleeding Events in Heart Failure: Insights from the JROADHF-NEXT

CJC Open. 2026 Jun 22;8(10):1288-1297. doi: 10.1016/j.cjco.2026.06.006. eCollection 2026 Oct.ABSTRACTBACKGROUND: Frail patients are considered to be at higher risk of bleeding than non-frail patients; however, the association between frailty and bleeding risk in patients with heart failure (HF) rema

T Taisuke Nakade

Inflammation Mediates the Relationship Between Serum Uric Acid and New-Onset Diabetes Risk in Patients with Coronary Heart Disease: Results from a Multicenter Cohort Study [Letter]

No abstractDiabetes Metab Syndr Obes. 2026 Oct 7;19:635777. doi: 10.2147/DMSO.S635777. eCollection 2026.NO ABSTRACTPMID:42861189 | PMC:PMC13654280 | DOI:10.2147/DMSO.S635777

L Liping Wei

Corrigendum to "Multicenter, randomized controlled study evaluating percutaneous and non-fluoroscopic procedure of atrial septal defects-study protocol of the PANASD randomized controlled trial" [Am. Heart J. Plus: Cardiol. Res. Pract. 64 (2026) 100747]

Am Heart J Plus. 2026 Aug 18;70:100851. doi: 10.1016/j.ahjo.2026.100851. eCollection 2026 Oct.ABSTRACT[This corrects the article DOI: 10.1016/j.ahjo.2026.100747.].PMID:42861184 | PMC:PMC13654359 | DOI:10.1016/j.ahjo.2026.100851

J Junke Chang

Incremental prognostic value of hepatic tissue alterations derived from cardiac magnetic resonance imaging for arrhythmogenic right ventricular cardiomyopathy: a case-control study

Quant Imaging Med Surg. 2026 Oct 1;16(10):786. doi: 10.21037/qims-2026-1125. Epub 2026 Aug 30.ABSTRACTBACKGROUND: Hepatic injury occurs in patients with cardiovascular disease and is associated with adverse clinical outcomes. The prognostic value of hepatic tissue alterations in patients with arrhyt

X Xiahui Tian

Optical Coherence Tomography Findings Following Intravascular Lithotripsy in Calcified Coronary Artery Disease: A Systematic Review and Meta-Analysis

CJC Open. 2026 Jul 1;8(10):1399-1418. doi: 10.1016/j.cjco.2026.06.016. eCollection 2026 Oct.ABSTRACTBACKGROUND: Intravascular lithotripsy (IVL) has emerged as a novel technology for modifying calcified coronary lesions, whereas optical coherence tomography (OCT) enables high-resolution assessment of

G Giacomo Maria Cioffi

Unipolar electrogram-guided vs. ablation index-guided high-power short-duration pulmonary vein isolation in patients with paroxysmal atrial fibrillation: a single-center randomized controlled trial

Quant Imaging Med Surg. 2026 Oct 1;16(10):794. doi: 10.21037/qims-2026-0593. Epub 2026 Sep 18.ABSTRACTBACKGROUND: Pulmonary vein isolation (PVI) is the cornerstone of catheter ablation for paroxysmal atrial fibrillation (PAF). The ablation index (AI) provides an estimate of lesion size and depth, bu

W Wei-Wei Wang