Role of CYP3A5 and CYP3A4 in the metabolism and toxicity of 10-hydroxyl mesaconitine, a new potential toxicity marker of Radix Aconiti Lateralis Preparata (Fuzi), in vitro and in vivo
Drug Metab Dispos. 2026 Jun 29;54(8):100352. doi: 10.1016/j.dmd.2026.100352. Online ahead of print.ABSTRACT10-Hydroxyl mesaconitine (10-OH MA) is a new potential toxicity marker of Radix Aconiti Lateralis Preparata (Fuzi), which is widely used for the treatment of cardiovascular diseases, rheumatoid

