Artificial Intelligence in Cardiovascular Disease Prevention: Current Applications and Future Perspectives

Anatol J Cardiol. 2026 Apr 15. doi: 10.14744/AnatolJCardiol.2026.6274. Online ahead of print.ABSTRACTCardiovascular diseases (CVDs) remain the leading cause of morbidity and mortality worldwide, emphasizing the ongoing need for effective and scalable primary and secondary prevention strategies. In t

N Nurgül Keser

Integration of a polygenic score into clinical risk prediction of atherosclerotic cardiovascular disease in familial hypercholesterolemia

Eur J Prev Cardiol. 2026 Apr 15:zwag203. doi: 10.1093/eurjpc/zwag203. Online ahead of print.ABSTRACTAIM: A high polygenic score for coronary artery disease (PRSCAD) has been demonstrated to be a strong and independent predictor of atherosclerotic cardiovascular disease (ASCVD) in patients with famil

M Martine Paquette

Metabolomics of Right Ventricular Function in Pulmonary Hypertension

Circ Res. 2026 Apr 15. doi: 10.1161/CIRCRESAHA.125.327342. Online ahead of print.ABSTRACTBACKGROUND: The metabolic mechanisms underlying right ventricular (RV) dysfunction are poorly understood, particularly outside of group 1 pulmonary hypertension (PH). We aimed to identify metabolites and pathway

J Jonathan Chacon-Barahona

Social Disconnection, Genetic Risk, and the Incidence of Degenerative Valvular Heart Disease: A Population-Based Cohort Study

J Am Heart Assoc. 2026 Apr 15:e045931. doi: 10.1161/JAHA.125.045931. Online ahead of print.ABSTRACTBACKGROUND: Degenerative valvular heart disease (VHD) is increasingly recognized as a major public health concern in aging populations. Although traditional cardiovascular risk factors have been extens

C Chenghui Cao

Effectiveness of Data-Driven Quality Improvement on Hospitalizations and Health Outcomes for People With Coronary Heart Disease in Primary Care (QUEL): A Cluster Randomized Controlled Trial With 24-Month Follow-Up

Circ Popul Health Outcomes. 2026 Apr 15:e012904. doi: 10.1161/CIRCOUTCOMES.125.012904. Online ahead of print.ABSTRACTBACKGROUND: This trial aimed to test the effectiveness of a data-driven quality improvement program in primary care on cardiovascular hospitalizations, major adverse cardiovascular ev

J Julie Redfern

Female-Biased VSMC GRNs Predict MYH9 as Regulator of Fibrous Plaque Phenotype

Circ Res. 2026 Apr 15. doi: 10.1161/CIRCRESAHA.125.326941. Online ahead of print.ABSTRACTBACKGROUND: Atherosclerosis, an inflammatory driver of coronary artery disease, manifests as unstable atheromatous plaques and stable fibrous plaques. Although atheromatous plaques have been extensively studied,

R R Noah Perry

Reversible Fibroblast Trajectories Regulated by MR Underlie Diastolic Dysfunction

Circ Res. 2026 Apr 15. doi: 10.1161/CIRCRESAHA.125.327301. Online ahead of print.ABSTRACTBACKGROUND: Heart failure with preserved ejection fraction (HFpEF) is a major health issue of our time. The pathophysiology of HFpEF is diverse, linked to comorbidities, such as kidney disease or obesity, and di

D David Meral

Evaluation after delayed and repeated intervention in the VIPVIZA-extended randomized controlled trial: beneficial results 6 years after baseline

Eur Heart J Open. 2026 Apr 13;6(2):oeag047. doi: 10.1093/ehjopen/oeag047. eCollection 2026 Mar.ABSTRACTAIMS: The Västerbotten Intervention Programme VIsualiZation of subclinical Atherosclerosis (VIPVIZA) pragmatic randomized controlled trial (RCT) previously reported reduced cardiovascular disease (

M Margareta Norberg

Exploring the relationship between remnant cholesterol and diabetic kidney disease in Chinese type 2 diabetes patients

Front Nutr. 2026 Mar 30;13:1793007. doi: 10.3389/fnut.2026.1793007. eCollection 2026.ABSTRACTBACKGROUND: Remnant cholesterol (RC) has been established as an independent risk factor for atherosclerotic cardiovascular disease. While the association between RC and diabetic kidney disease (DKD) remains

Y Yanli Li

Universal Early Discharge Protocol for Acute Myocardial Infarction: A Single-Center Prospective Validation

Vasc Health Risk Manag. 2026 Apr 9;22:581820. doi: 10.2147/VHRM.S581820. eCollection 2026.ABSTRACTBACKGROUND AND AIMS: Selected low-risk myocardial infarction (MI) patients may be safely discharged within 72 hours. The aim was to prospectively validate a previously created protocol for selecting low

D Dávid Bauer

Creative surgical solution for mechanical circulatory support in adult congenital heart disease: case report

Eur Heart J Case Rep. 2026 Apr 13;10(4):ytaf597. doi: 10.1093/ehjcr/ytaf597. eCollection 2026 Apr.ABSTRACTBACKGROUND: Advances in surgical and medical care have led to an increasing number of patients with congenital heart disease (CHD) surviving into adulthood. As a result, we must address the long

M Maria Grandinetti

Early electrocardiographic diagnosis of ST-segment elevation myocardial infarction during cardiac resynchronization via left bundle branch area pacing

No abstractEur Heart J Case Rep. 2025 Jul 11;10(4):ytaf319. doi: 10.1093/ehjcr/ytaf319. eCollection 2026 Apr.NO ABSTRACTPMID:41982978 | PMC:PMC13071809 | DOI:10.1093/ehjcr/ytaf319

A Alessio Cucco

Exploration of the expression and regulatory mechanisms of platelet miR-223-3p in hand, foot, and mouth disease (HFMD) complicated by encephalitis

Transl Pediatr. 2026 Mar 23;15(3):78. doi: 10.21037/tp-2025-aw-802. Epub 2026 Mar 18.ABSTRACTBACKGROUND: Hand, foot, and mouth disease (HFMD) complicated by encephalitis is a severe condition with an acute onset, yet its pathogenesis remains incompletely understood. This study aimed to investigate t

C Chun-Yu Lu

Translation, cross-cultural adaptation, and psychometric validation of the Chinese version of the Caregiver Contribution to Self-Care of Coronary Heart Disease Inventory

Front Public Health. 2026 Mar 30;14:1751188. doi: 10.3389/fpubh.2026.1751188. eCollection 2026.ABSTRACTOBJECTIVE: This study aimed to translate the Caregiver Contribution to Self-Care of Coronary Heart Disease Inventory, version 3a (CC-SC-CHDI v3a), into Chinese and evaluate its psychometric propert

Z Ziming He

Adverse Hemodynamics in Kommerell's Diverticulum: A Comparative Case Report Linking Oscillatory Shear Index to Aortic Dissection

Clin Case Rep. 2026 Apr 12;14(4):e72509. doi: 10.1002/ccr3.72509. eCollection 2026 Apr.ABSTRACTHemodynamic evaluation using four-dimensional flow magnetic resonance imaging or computational fluid dynamics can identify a high-risk phenotype in Kommerell's diverticulum, which is characterized by intra

K Kenji Sakakibara

HEARTS Pharmacy: A framework for integrating pharmacists in hypertension and cardiovascular disease risk management in primary careFarmacia HEARTS: um modelo para a integracao de farmaceuticos na gestao dos riscos de hipertensao arterial e doencas cardiovasculares na atencao primaria

Rev Panam Salud Publica. 2026 Apr 13;50:e35. doi: 10.26633/RPSP.2026.35. eCollection 2026.ABSTRACTHEARTS Pharmacy, a project within the HEARTS in the Americas Initiative, provides a framework to integrate pharmacists into primary health care. Pharmacists are highly respected in health care but face

E Emily Ridley

A Rare Case Report of Central Retinal Artery Occlusion in a Young Female Post-Fontan Procedure: Clinical Implications and Management

J Curr Ophthalmol. 2026 Mar 18;37(3):371-374. doi: 10.4103/joco.joco_272_24. eCollection 2025 Jul-Sep.ABSTRACTPURPOSE: To highlight the importance of recognizing the risk factors for central retinal artery occlusion (CRAO) in patients with congenital heart diseases, as CRAO is a rare but severe cond

H Hanan Khalid Aljaidi

The Impact on Systematic Reviews of Risk of Bias Assessment Changes From Conference Abstracts to Full Text

Cochrane Evid Synth Methods. 2026 Mar 27;4(3):e70078. doi: 10.1002/cesm.70078. eCollection 2026 May.ABSTRACTConference abstracts are commonly included in systematic reviews of evidence. Due to limitations in word count, conference abstracts often lack data or information. This causes issues for the

R Ryan P W Kenny

Association Between Observed Climate Change and Cardiovascular Disease in the United States

Geohealth. 2026 Apr 13;10(4):e2025GH001588. doi: 10.1029/2025GH001588. eCollection 2026 Apr.ABSTRACTClimate change is affecting nearly all social and environmental determinants of health. However, the extent of resulting cumulative impacts on cardiovascular and other noncommunicable diseases is not

R R Yeager

The global roadmap for cardiovascular imaging: bridging the diagnostic divide

Eur Heart J Imaging Methods Pract. 2026 Feb 28;4(1):qyag031. doi: 10.1093/ehjimp/qyag031. eCollection 2026 Jan.ABSTRACTLow- and middle-income countries suffer from stark disparities in access to diagnostic cardiovascular imaging services. These inequities lead to delayed diagnoses, mismanagement of

P Partho P Sengupta

Arterial stenosis and electrophysiological nerve dysfunction in type 2 diabetes: clinical evidence from GEE models and transcriptomic pathway analysis

Front Endocrinol (Lausanne). 2026 Mar 30;17:1758863. doi: 10.3389/fendo.2026.1758863. eCollection 2026.ABSTRACTBACKGROUND: Diabetic peripheral neuropathy (DPN) is a common disabling complication of type 2 diabetes (T2D), yet the contribution of systemic arterial stenosis to electrophysiological nerv

X Xiu-Qin Zhao

Case Report: Two infants with hypercalcemia of rare and distinct etiologies

Front Endocrinol (Lausanne). 2026 Mar 30;17:1799236. doi: 10.3389/fendo.2026.1799236. eCollection 2026.ABSTRACTOBJECTIVES: Hypercalcemia in infancy is rare and often presents with nonspecific clinical signs, making early recognition challenging. This report describes two infants with severe symptoma

I Ivona Butorac Ahel

Association between admission hemoglobin-to-red blood cell distribution width ratio and stroke-associated pneumonia risk in acute ischemic stroke: effect modification by diabetes status

Front Endocrinol (Lausanne). 2026 Mar 30;17:1778191. doi: 10.3389/fendo.2026.1778191. eCollection 2026.ABSTRACTOBJECTIVE: This study aimed to assess the relationship between admission hemoglobin-to-red blood cell distribution width ratio (HRR) and stroke-associated pneumonia (SAP) risk in patients w

H Hui Du

Association between insulin resistance trajectories and perinatal complications: a retrospective cohort study

Front Endocrinol (Lausanne). 2026 Mar 30;17:1746255. doi: 10.3389/fendo.2026.1746255. eCollection 2026.ABSTRACTBACKGROUND: During pregnancy, the maternal body undergoes adaptive regulation to support the normal growth and development of the fetus, such as the occurrence of insulin resistance (IR). W

L Lisha Ye