Kidney function and acid-base status as gatekeepers of natriuretic and diuretic responsiveness in chronic HF: insights from the DEA-HF clinical trial

Eur Heart J Cardiovasc Pharmacother. 2026 May 18:pvag019. doi: 10.1093/ehjcvp/pvag019. Online ahead of print.ABSTRACTAIMS: In chronic heart failure (HF), decongestion is hindered by reduced renal function and diuretic resistance. This study compared the effect of eGFR and serum bicarbonate on three

I Ina Volis

Polygenic risk scores for cardiovascular disease: clinical utility and limitations

Egypt Heart J. 2026 May 18;78(1):34. doi: 10.1186/s43044-026-00746-3.ABSTRACTBACKGROUND: Cardiovascular diseases (CVDs) are the leading cause of mortality worldwide, highlighting the need for improved risk prediction and prevention strategies. Polygenic Risk Scores (PRS), derived from genome-wide as

F Faith Adedayo Adejumo

Combining external placebo-arm data in a prevention trial: effects of cocoa extract supplementation on cardiovascular disease

No abstractEur J Epidemiol. 2026 May 18. doi: 10.1007/s10654-026-01361-x. Online ahead of print.NO ABSTRACTPMID:42149390 | DOI:10.1007/s10654-026-01361-x

R Rikuta Hamaya

Clinical and Radiological Characteristics of Patients with Lophomonas blattarum Detected in Bronchial Lavage: A Single-Center Experience

Eur J Clin Microbiol Infect Dis. 2026 May 18. doi: 10.1007/s10096-026-05539-9. Online ahead of print.ABSTRACTINTRODUCTION: Lophomonas blattarum (L. blattarum) is an emerging protozoan increasingly reported in respiratory specimens. This study aimed to characterize the clinical and radiological featu

D Demet Polat Yulug

Electroacupuncture Promotes Synaptic Recovery After Cerebral Ischemia-Reperfusion by Activating SIRT1 to Inhibit the NF-κB Pathway and Regulate Astrocyte Phenotypic Transformation

Neurochem Res. 2026 May 18;51(3):159. doi: 10.1007/s11064-026-04775-x.ABSTRACTFunctional recovery after cerebral ischemia-reperfusion injury (CIRI) depends on synaptic plasticity, which is profoundly modulated by astrocyte phenotypes-the neurotoxic A1 phenotype exacerbates damage, while the A2 pheno

Q Qing Song

Cardiac Electrophysiologic Effects of Different Local Anesthetics in Langendorff-Perfused Rabbit Hearts

Cardiovasc Toxicol. 2026 May 18;26(6):51. doi: 10.1007/s12012-026-10122-x.ABSTRACTLocal anesthetics are widely used in medical care. However, their sodium channel blocking properties not only explain their analgesic potency but also their possible cardiotoxic effects. Due to the different pharmacody

J Julian Wolfes

Posttraumatic Stress Symptoms in Patients on Ventricular Assist Device Support: Something to Worry About?

Clin Transplant. 2026 May;40(5):e70556. doi: 10.1111/ctr.70556.ABSTRACTBACKGROUND: Psychosocial outcome in ventricular assist device (VAD) patients continues to merit evaluation including posttraumatic stress symptoms (PTSS).METHODS: A cross-sectional multicenter study collected data from 265 VAD pa

C Christiane Kugler

Cell based therapy in chronic kidney disease: emerging evidence for a fifth pillar in guideline directed medical therapy

Clin Exp Nephrol. 2026 May 18. doi: 10.1007/s10157-026-02891-0. Online ahead of print.ABSTRACTChronic kidney disease (CKD) affects over 800 million individuals globally and is a primary aetiology of premature cardiovascular mortality. Despite advancements in pharmacological therapies, these strategi

G Gerry George Mathew

Assessing the spatial clustering of climate change-related cardiovascular disease mortality in Iran: a spatiotemporal analysis approach

Int J Biometeorol. 2026 May 18;70(6):163. doi: 10.1007/s00484-026-03161-0.ABSTRACTCardiovascular diseases (CVD) are a major global health challenge, with rising prevalence, high mortality and disability rates, and significant economic costs. Emerging research suggests that climate change worsens the

A Alireza Zangeneh

Association of thrombogenicity indices with perioperative cardiovascular events after non-cardiac surgery: a prespecified analysis of the PANDA study

J Thromb Thrombolysis. 2026 May 18. doi: 10.1007/s11239-026-03299-z. Online ahead of print.ABSTRACTTraditional clinical risk models, such as Revised Cardiac Risk Index (RCRI), have limited predictive value for estimating postoperative cardiovascular complications following non-cardiac surgery. This

H Hendrianus Hendrianus

Edoxaban for treatment of cancer-related isolated distal deep vein thrombosis: harnessing evidence, seeking equipoise

No abstractJ Thromb Thrombolysis. 2026 May 18. doi: 10.1007/s11239-026-03319-y. Online ahead of print.NO ABSTRACTPMID:42149308 | DOI:10.1007/s11239-026-03319-y

A Andrea Minghini

Clinical outcomes of anemia in patients with spontaneous coronary artery dissection: a retrospective cohort analysis

J Thromb Thrombolysis. 2026 May 18. doi: 10.1007/s11239-026-03314-3. Online ahead of print.ABSTRACTSpontaneous coronary artery dissection (SCAD) is an increasingly recognized cause of acute coronary syndrome, especially in younger patients and women. Anemia, a common comorbidity in patients with car

E Emmanuel Olumuyide

Edoxaban for atrial fibrillation in patients with atherosclerotic disease in daily clinical practice

J Thromb Thrombolysis. 2026 May 18. doi: 10.1007/s11239-026-03269-5. Online ahead of print.ABSTRACTTo estimate major clinical event rates for patients with atrial fibrillation (AF) and atherosclerotic disease treated with edoxaban in routine practice, and to evaluate how well such patients were repr

T Tim A C de Vries

The association of angiostatin and plasminogen plasma levels with Charlson comorbidity burden and mortality in COVID-19

J Thromb Thrombolysis. 2026 May 18. doi: 10.1007/s11239-026-03289-1. Online ahead of print.ABSTRACTSevere COVID-19 is associated with thrombotic complications. Dysregulated fibrinolysis, marked by increased plasminogen activator inhibitor-1 (PAI-1) and reduced plasmin generation, has been linked to

A Aleksandra Franczak

Vessel wall enhancement in brain arteriovenous malformations: associations with imaging and histopathological markers of instability

Neurosurg Rev. 2026 May 18;49(1):405. doi: 10.1007/s10143-026-04336-4.ABSTRACTIn brain arteriovenous malformations (bAVMs), whether vessel wall enhancement on magnetic resonance vessel wall imaging (VWI) is associated with hemorrhage and other imaging and histopathological markers of instability rem

M Masaki Ujihara

Unraveling Atherosclerosis through Multi-omics: Systematic Insights into the Unique Applications and Clinical Perspectives

Curr Atheroscler Rep. 2026 May 18;28(1):50. doi: 10.1007/s11883-026-01420-4.ABSTRACTPURPOSE OF REVIEW: Atherosclerosis (AS) is a progressive disease of the arterial wall characterized by metabolic dysregulation, inflammatory activation, and genetic susceptibility. Given the complex interactions acro

X Xin Zhong

Effect of ambient temperature changes on the treatment and prognosis in patients with acute stroke receiving intravenous thrombolysis

Int J Biometeorol. 2026 May 18;70(6):164. doi: 10.1007/s00484-026-03232-2.ABSTRACTWe determined whether environmental temperature affects the time delay and clinical outcomes in patients with acute ischemic stroke receiving intravenous recombinant tissue plasminogen activator (rt-PA) thrombolysis. W

T Tianli Zhang

Duration of heart failure as a determinant of outcomes after left ventricular assist device implantation: an international multicenter study

Clin Res Cardiol. 2026 May 18. doi: 10.1007/s00392-026-02938-y. Online ahead of print.ABSTRACTBACKGROUND: While heart failure (HF) duration before left ventricular assist device (LVAD) implantation may influence postoperative outcomes, data evaluating this relationship remains limited. This study in

M Miloud Cherbi

Association of DAPT duration with bleeding and ischemic outcomes after percutaneous coronary intervention with drug-coated balloons: a meta-analysis

Clin Res Cardiol. 2026 May 18. doi: 10.1007/s00392-026-02934-2. Online ahead of print.ABSTRACTINTRODUCTION: Drug-coated balloons (DCB) represent a promising tool in percutaneous coronary intervention (PCI), enabling a "leave nothing behind" strategy. Evidence guiding the optimal duration of dual ant

G Giuseppe Panuccio

Risk factors and the impact of comorbidities in patients developing urethral stricture after transurethral resection of the prostate

World J Urol. 2026 May 18;44(1):367. doi: 10.1007/s00345-026-06473-3.ABSTRACTPURPOSE: Urethral stricture remains a clinically relevant complication after transurethral resection of the prostate (TURP). While procedural factors have been extensively studied, the contribution of systemic comorbidities

M Mahmut Uğurlu

Microbubble Contrast Agents for Molecular Ultrasound Imaging of Tumor Vasculature

Recent Results Cancer Res. 2026;224:343-355. doi: 10.1007/978-3-032-15314-2_10.ABSTRACTMolecular ultrasound imaging was proposed more than two decades ago. The ultrasound contrast agents used for selective targeting of vascular biomarkers of disease are formulated as gas microbubbles surrounded by a

A Alexander L Klibanov

Growth Differentiation Factor-15 in Diabetic Kidney and Cardiovascular Disease: Pathogenic Driver or Protective Modulator

Diabetes. 2026 May 18:db260133. doi: 10.2337/db26-0133. Online ahead of print.ABSTRACTDiabetic kidney disease (DKD) and diabetic cardiomyopathy continue to drive excess morbidity and mortality in diabetes, underscoring a critical gap between mechanistic insight and clinical translation. Growth diffe

A Amani Slika

HFpEF, Aging, Inflammaging, and the Future of Anti-Inflammatory: Therapy in Heart Failure with Preserved Ejection Fraction

Aging Dis. 2026 May 2. doi: 10.14336/AD.2026.0265. Online ahead of print.ABSTRACTAging is the dominant risk factor for heart failure with preserved ejection fraction (HFpEF), a condition increasingly recognized as a manifestation of maladaptive cardiovascular aging. This review summarizes current ev

A Arkadiusz Grzeczka

Serum Calcification Propensity and CPP2 Size - Deranged Mineral Buffering and The Risk of Mortality in Older Adults

Aging Dis. 2026 May 13. doi: 10.14336/AD.2025.1335. Online ahead of print.ABSTRACTAgeing is associated with increased vascular calcification. However, the parallels with chronic kidney disease are unclear, where secondary calciprotein particles (CPP2) are increasingly formed due to insufficient mine

M Mirjam Schuchardt