Estradiol-PGC-1 signaling in mitochondrial health: Implications for perimenopause and cardiovascular disease

Physiol Rep. 2026 Oct;14(20):e71155. doi: 10.14814/phy2.71155.ABSTRACTCardiovascular disease (CVD) is the leading cause of death in aging women. While CVD etiology is multifactorial, mitochondrial dysfunction, characterized by reduced content, impaired energy production, and increased oxidative stre

A Alyssa L Parten

Lunar phases, meteorological conditions, astrological signs, and postoperative outcomes of acute type A aortic dissection: Results of a retrospective cohort study

Perfusion. 2026 Oct 21:2676591261495414. doi: 10.1177/02676591261495414. Online ahead of print.ABSTRACTBackgroundAcute type A aortic dissection (ATAAD) is a surgical emergency associated with high mortality. While patient-related risk factors are well-established, beliefs persist regarding the influ

L Laurent Mathieu

Lysosomal protein transmembrane 5 protects against myocardial ischemia-reperfusion injury by promoting mitophagy via the NEDD4-LC3 axis

Clin Transl Med. 2026 Oct;16(10):e70876. doi: 10.1002/ctm2.70876.ABSTRACTBACKGROUND: Mitophagy is essential for mitochondrial quality control during myocardial ischemia-reperfusion (I/R) injury. Lysosomal protein transmembrane 5 (LAPTM5) has been implicated in cardiovascular disease and autophagy, b

Y Yadan Zhang

Structural Valve Deterioration in End-Stage Renal Disease Patients With Transcatheter Aortic Valve Replacement

Cardiol Rev. 2026 Oct 22. doi: 10.1097/CRD.0000000000001510. Online ahead of print.ABSTRACTTranscatheter aortic valve replacement (TAVR) has revolutionized the management of aortic stenosis (AS), particularly for high-risk and inoperable populations. Nevertheless, patients with end-stage renal disea

B Berk Inan

Socioeconomic factors and out-of-pocket healthcare spending among older adults with hypertension and type 2 diabetes in the US: findings from the 2018-2022 MEPS data

BMC Health Serv Res. 2026 Jul 25;26(1):1450. doi: 10.1186/s12913-026-15188-5.ABSTRACTBACKGROUND: Type 2 diabetes and hypertension often co-occur significantly, adding to patients' healthcare economic expenditure, especially among older adults. This study examined socioeconomic factors associated wit

T Tonghui Xu

Post-hemorrhagic ventricular dilatation and hydrocephalus in preterm infants: a five-year retrospective cohort study from a tertiary referral center

BMC Pediatr. 2026 Jul 25;26(1):1046. doi: 10.1186/s12887-026-07398-x.ABSTRACTBACKGROUND: Post-hemorrhagic hydrocephalus (PHH) is a serious complication of intraventricular hemorrhage (IVH) in preterm infants and is associated with increased morbidity and mortality. Although neonatal risk factors are

H Hamide Barzegar

Triglyceride glucose index, metabolic comorbidity, and cardiovascular disease: a national cohort study

BMC Cardiovasc Disord. 2026 Sep 16;26(1):959. doi: 10.1186/s12872-026-06618-7.ABSTRACTBACKGROUND: The triglyceride-glucose (TyG) index, a widely accepted surrogate biomarker of insulin resistance, strongly predicts cardiovascular disease (CVD) risk. However, the mediating role of metabolic comorbidi

Y Yuanmei Chen

ApoB/ApoA-I ratio and all-cause mortality in maintenance hemodialysis: a cohort study

BMC Nephrol. 2026 Jul 25;27(1):625. doi: 10.1186/s12882-026-05224-1.ABSTRACTBACKGROUND: Traditional lipid markers have limited and inconsistent prognostic value in maintenance hemodialysis (MHD), a phenomenon often described as the lipid paradox. We evaluated whether lipid and apolipoprotein-related

Z Zhen Zhang

Comparative evaluation of serum TGF-beta1 and PDGF-BB levels across patients with normal coronary arteries, stable coronary artery disease, and acute coronary syndrome

BMC Cardiovasc Disord. 2026 Jul 27;26(1):960. doi: 10.1186/s12872-026-06346-y.ABSTRACTBACKGROUND: To compare serum levels of Transforming Growth Factor-Beta (TGF-β) and Platelet-Derived Growth Factor-BB (PDGF-BB) among patients with normal coronary arteries (NCA) and those with coronary artery disea

V Veli Küçüksevgili

Development and external validation of a preoperative prediction model for in-hospital major adverse cardiovascular events after hip fracture surgery in older adults: a retrospective two-center study

BMC Geriatr. 2026 Jul 27;26(1):1329. doi: 10.1186/s12877-026-07981-y.ABSTRACTBACKGROUND: Older adults with hip fracture are vulnerable to postoperative major adverse cardiovascular events (MACE) during hospitalization. However, early risk stratification remains difficult because existing assessments

R Ruimin Luo

Circulating 16 micronutrients concentration and risk of abdominal aortic aneurysm: a two-sample mediation Mendelian randomization analysis

J Cardiothorac Surg. 2026 Jul 25;21(1):834. doi: 10.1186/s13019-026-04593-w.ABSTRACTBACKGROUND: Abdominal aortic aneurysm (AAA) is a severe cardiovascular disease involving various genetic and metabolic factors. Micronutrients play critical roles in cardiovascular health, yet their specific impacts

W Wenpeng Zhao

Accelerated intermittent theta burst stimulation (iTBS) for the upper limb recovery after subacute stroke (ATLAS): study protocol for a multicenter randomized controlled trial

Trials. 2026 Jul 24;27(1):619. doi: 10.1186/s13063-026-09857-3.ABSTRACTBACKGROUND: Stroke is the second leading cause of death globally, with residual upper limb dysfunction being a major contributor to its high disability rate. Currently, there remains a lack of effective rehabilitation approaches

H Hong Yang

Risk factors and outcomes of early postoperative complications following congenital heart surgery: a retrospective study at a tertiary care hospital in Nairobi, Kenya

J Cardiothorac Surg. 2026 Jul 25;21(1):832. doi: 10.1186/s13019-026-04403-3.ABSTRACTINTRODUCTION: Congenital Heart Disease (CHD) remains a major health challenge globally, with surgical interventions being the primary treatment modality for many defects. While advancements in cardiac surgery have im

N Nasra Ismail Adan

Severe continuous prosthetic mitral regurgitation from chordal rupture after valve-sparing replacement: a case report

J Cardiothorac Surg. 2026 Jul 26;21(1):831. doi: 10.1186/s13019-026-04656-y.ABSTRACTBACKGROUND: After mitral valve replacement with preservation of the subvalvular apparatus, prosthetic dysfunction resulting from retained native structures is extremely rare. When it occurs, it may directly threaten

H Hongxia Wang

Enhanced glucose uptake in cardiac and skeletal muscles in Danon disease results from the impaired chaperone-mediated autophagy

Cell Biosci. 2026 Jul 26;16(1):116. doi: 10.1186/s13578-026-01625-9.ABSTRACTDanon disease (DD) is a rare X-linked lysosomal storage disorder that predominantly affects cardiac and skeletal muscles, characterized by glycogen and autophagic material accumulation. DD is caused by mutations in LAMP2, en

W Wei Lai

A giant left ventricular aneurysm in an apparently asymptomatic child. the value of multimodality assessment for risk stratification

J Cardiothorac Surg. 2026 Jul 26;21(1):830. doi: 10.1186/s13019-026-04605-9.ABSTRACTBACKGROUND: Congenital left ventricular aneurysm (LVA) is a rare abnormality most commonly located at the LV apex. It must be differentiated from left ventricular diverticulum (LVD). Congenital LVA is typically isola

S Soha Sadeghpoor Tabaei

Minocycline for acute basilar artery occlusion stroke undergoing endovascular treatment: a randomized, evaluator-blinded, open-label, pilot trial

BMC Med. 2026 Jul 27;24(1):580. doi: 10.1186/s12916-026-05092-4.ABSTRACTBACKGROUND: Minocycline is a promising anti-inflammatory agent for reducing futile recanalization, but whether it improves clinical outcomes in basilar-artery stroke patients treated with endovascular therapy (EVT) remains uncle

Z Zhirong Fan

Clinical, radiological, and pathological features of pulmonary hypertension associated with combined pulmonary fibrosis and emphysema

Respir Res. 2026 Jul 27;27(1):417. doi: 10.1186/s12931-026-03828-7.ABSTRACTBACKGROUND: Combined pulmonary fibrosis and emphysema-associated pulmonary hypertension (CPFE-PH) has emerged as a distinct third category of PH, yet its detailed clinical-hemodynamic profile, pathological features, and compa

M Mengyu He

Proteomic signatures characterized by inflammatory signaling and metabolic processes have divergent associations with 30-year incidence of coronary artery disease in type 1 diabetes: the Pittsburgh Epidemiology of Diabetes Complications cohort

Cardiovasc Diabetol. 2026 Jul 26;25(1):311. doi: 10.1186/s12933-026-03313-x.ABSTRACTBACKGROUND: While inflammation is hypothesized to be a possible driver of the excess coronary artery disease (CAD) observed in type 1 diabetes, prior biomarker studies have focused on candidate proteins, overlooking

J J Zhou

The impact of personalized nursing care plans based on the modified Patient-Generated Subjective Global Assessment (abPG-SGA) on postoperative nutritional status in patients undergoing colorectal cancer surgery

BMC Surg. 2026 Jul 27;26(1):707. doi: 10.1186/s12893-026-03821-3.ABSTRACTPURPOSE: To assess the impact of personalized nursing care plans, based on the modified abPG-SGA, on postoperative nutritional status in patients undergoing colorectal cancer surgery.METHODS: A retrospective cohort analysis was

T Tingfang Lv

Nomogram construction and validation for hypoalbuminemia after total hip arthroplasty in patients with hip fractures

BMC Musculoskelet Disord. 2026 Jul 25;27(1):897. doi: 10.1186/s12891-026-10125-3.ABSTRACTBACKGROUND: To investigate the risk factors for hypoalbuminemia after total hip arthroplasty (THA) in patients with hip fractures and to establish and validate a risk prediction nomogram.METHODS: A retrospective

X Xiaodong Jia

Unraveling the dual role of fibroblast growth factor 5 (FGF5) in cardiorenal diseases through multi-omics causal inference

Cardiovasc Diabetol. 2026 Jul 26;25(1):310. doi: 10.1186/s12933-026-03309-7.ABSTRACTBACKGROUND: As populations age worldwide, multimorbidity has become an increasingly prominent public health challenge. Among age-associated conditions, cardiovascular diseases (CVDs) are among the most prevalent and

T Ting Zan

Diabetic retinopathy enhances coronary artery calcium-based cardiovascular risk stratification in patients with type 2 diabetes: insights from the ACCoDiab study

Cardiovasc Diabetol. 2026 Jul 27;25(1):309. doi: 10.1186/s12933-026-03314-w.ABSTRACTBACKGROUND: The coronary artery calcium (CAC) score is a validated imaging biomarker enhancing cardiovascular risk stratification in patients with type 2 diabetes mellitus (T2DM). However, residual risk persists, par

F Franck Phan

Experiences, barriers and enablers of stroke end-of-life care: a systematic review with mixed-methods synthesis

BMC Palliat Care. 2026 Jul 27;25(1):317. doi: 10.1186/s12904-026-02211-z.ABSTRACTBACKGROUND: Despite advances in stroke care, 12% of patients die within 30 days of stroke highlighting the requirement for high-quality end-of-life care (EoLC) within stroke services. EoLC aims to improve the quality-of

C Clare Gordon