Genet Med. 2026 Jun 19:102633. doi: 10.1016/j.gim.2026.102633. Online ahead of print.ABSTRACTPURPOSE: We aim to better define the genotype and phenotype spectrum of RNU4ATAC-opathy, demonstrate the utility of RNA sequencing for variant classification, and highlight challenges in detecting variants i
Diabet Med. 2026 Jun 20:e70396. doi: 10.1111/dme.70396. Online ahead of print.ABSTRACTAIMS: Kidney fibrosis, characterised by impaired extracellular matrix remodelling and excessive collagen deposition, is a hallmark of chronic kidney disease in diabetes. We investigated whether biomarkers reflectin
Traffic. 2026 Sep;27(3):e70039. doi: 10.1111/tra.70039.ABSTRACTEps15 homology domain-containing proteins comprise a conserved family of membrane-remodeling ATPases that regulate endocytic trafficking, membrane fission, receptor recycling, primary ciliogenesis and membrane dynamics across eukaryotes.
Pharmacoepidemiol Drug Saf. 2026 Jul;35(7):e70405. doi: 10.1002/pds.70405.ABSTRACTBACKGROUND: Men with castration-resistant prostate cancer (CRPC) who have a pre-existing history of cardiovascular disease (CVD) or other comorbidities are often excluded from clinical trials involving oral androgen re
Nutr Bull. 2026 Jun 20. doi: 10.1111/nbu.70050. Online ahead of print.ABSTRACTObesity is a global health issue linked to increased risks of type 2 diabetes and cardiovascular diseases. A reduced resting metabolic rate contributes to obesity. Plant-based diets are often recommended for weight control
Ann Med. 2026 Dec;58(1):2534083. doi: 10.1080/07853890.2025.2534083. Epub 2026 Jun 19.ABSTRACTOBJECTIVES: This meta-analysis aimed to evaluate the association between endometriosis (EM) and cardiovascular disease (CVD) risk by synthesizing evidence from large-scale cohort studies, with emphasis on s
No abstractGeriatr Gerontol Int. 2026 Jun;26(6):e70603. doi: 10.1111/ggi.70603.NO ABSTRACTPMID:42322077 | DOI:10.1111/ggi.70603
Brief inhalation of carbon dioxide (CO(2)) has been proposed to counteract transient hypocapnia by enhancing oxygen unloading, vasodilation, and sympathetic modulation. Despite these potential ergogenic mechanisms, CO(2) has rarely been investigated in the exercise context. The present study investi
J Cannabis Res. 2026 Jun 19. doi: 10.1186/s42238-026-00463-3. Online ahead of print.ABSTRACTBACKGROUND: Hypertension is a leading risk factor for cardiovascular disease, particularly in ageing populations. While pharmacological interventions are common, issues with long-term adherence and side effec
J Transl Med. 2026 Jun 19. doi: 10.1186/s12967-026-08492-5. Online ahead of print.ABSTRACTBACKGROUND: Environmental factors such as cold exposure have been increasingly recognized as contributors to atherosclerosis progression, yet the underlying mechanisms linking environmental stress to vascular p
J Cardiothorac Surg. 2026 Jun 19. doi: 10.1186/s13019-026-04416-y. Online ahead of print.ABSTRACTBACKGROUND: The increasing prevalence of obesity worldwide has led to conflicting research on its cardiovascular effects. Although obesity is an established risk factor for cardiovascular disease (CVD),
J Cardiothorac Surg. 2026 Jun 19. doi: 10.1186/s13019-026-04450-w. Online ahead of print.ABSTRACTPeripheral vascular interventions (PVIs) are less invasive alternatives to surgical bypass. However, the impact of PVIs on the post-procedural quality of life of patients and workload of nurses remains u
J Nanobiotechnology. 2026 Jun 19. doi: 10.1186/s12951-026-04695-6. Online ahead of print.ABSTRACTBACKGROUND: Lung adenocarcinoma (LUAD) remains a leading cause of cancer-related mortality, and currently available serum biomarkers have limited sensitivity and specificity for early diagnosis. We inves
J Cardiothorac Surg. 2026 Jun 19. doi: 10.1186/s13019-026-04437-7. Online ahead of print.ABSTRACTBACKGROUND: In 2023, the American Heart Association introduced the cardiovascular-kidney-metabolic (CKM) syndrome to comprehensively assess multimorbidity involving obesity, diabetes, chronic kidney dise
J Cardiothorac Surg. 2026 Jun 19. doi: 10.1186/s13019-026-04438-6. Online ahead of print.ABSTRACTBACKGROUND: Coronary artery bypass grafting (CABG) is the gold standard treatment for advanced coronary artery disease (CAD). Postoperative complications can be life-threatening, particularly in patients
Cardiovasc Diabetol. 2026 Jun 19. doi: 10.1186/s12933-026-03252-7. Online ahead of print.ABSTRACTBACKGROUND: Lipoprotein(a) [Lp(a)] is a genetically determined and independent cardiovascular risk factor, traditionally considered stable across the lifespan, supporting a single lifetime measurement st
BMC Nephrol. 2026 Jun 19. doi: 10.1186/s12882-026-05140-4. Online ahead of print.ABSTRACTBACKGROUND: Cardiovascular disease is the leading cause of death among patients undergoing hemodialysis, while effective preventive strategies remain limited. Omega-3 polyunsaturated fatty acids (n-3 PUFAs) have
BMC Cardiovasc Disord. 2026 Jun 19. doi: 10.1186/s12872-026-06146-4. Online ahead of print.ABSTRACTBACKGROUND: Arrhythmias such as atrial fibrillation and bradyarrhythmia impose a substantial public health burden. Although genetic predisposition contributes to arrhythmia risk, the extent to which mo
BMC Cardiovasc Disord. 2026 Jun 19. doi: 10.1186/s12872-026-06106-y. Online ahead of print.ABSTRACTBACKGROUND: Functional mitral regurgitation (FMR) carries poor prognosis, and optimal management remains debated. Mitral Transcatheter Edge-to-Edge Repair (MTEER) is an alternative to surgical repair (
BMC Cardiovasc Disord. 2026 Jun 19. doi: 10.1186/s12872-026-06151-7. Online ahead of print.ABSTRACTOBJECTIVES: This study aimed to evaluate whether peroxisome proliferator-activated receptor gamma coactivator-1 alpha (PGC-1α) could serve as a marker of myocardial ischemia by examining its associatio
No abstractHeart Vessels. 2026 Jun 20. doi: 10.1007/s00380-026-02725-9. Online ahead of print.NO ABSTRACTPMID:42321566 | DOI:10.1007/s00380-026-02725-9
No abstractHeart Vessels. 2026 Jun 20. doi: 10.1007/s00380-026-02726-8. Online ahead of print.NO ABSTRACTPMID:42321564 | DOI:10.1007/s00380-026-02726-8
Discov Oncol. 2026 Jun 19. doi: 10.1007/s12672-026-05365-7. Online ahead of print.ABSTRACTDipyridamole is a well-known antithrombotic and a vasodilator. It is used to treat cerebrovascular and cardiovascular diseases owing to its antiplatelet effects. Platelets play a key role in thrombosis and hemo
Drugs Aging. 2026 Jun 19. doi: 10.1007/s40266-026-01305-w. Online ahead of print.ABSTRACTBACKGROUND: Inappropriate prescribing in Sri Lankan older adults, contributes to adverse drug events, hospital admissions and increased healthcare expenditure. Although international tools exist to assess prescr
