A Cardiovascular Care Pathway Supported by Remote Patient Management in Dutch Primary Care: Cost-Effectiveness, Budget Impact, and Workload Analysis

JMIR Mhealth Uhealth. 2026 Sep 28;14:e79512. doi: 10.2196/79512.ABSTRACTBACKGROUND: Remote patient management (RPM) that supports patient self-monitoring of vital parameters and lifestyle factors may improve cardiovascular risk management (CVRM) in primary care. However, large-scale implementation r

J Jan Heijdra Suasnabar

Cardiovascular Risk Triage Schema for Patients With Prostate Cancer Treated With Hormone Therapy

JCO Oncol Pract. 2026 Sep 28:OP2600312. doi: 10.1200/OP-26-00312. Online ahead of print.ABSTRACTIMPORTANCE: Cardiovascular disease (CVD) is a leading noncancer cause of death among patients with prostate cancer (PC). Population-based risk calculators do not account for treatment-related effects of a

A Avirup Guha

Negative Static Lung Load and Immersion Pulmonary Edema in Healthy Divers: The Determinant Role of Breathing-Gas Source Position

Med Sci Sports Exerc. 2026 Sep 28. doi: 10.1249/MSS.0000000000004159. Online ahead of print.ABSTRACTPURPOSE: Immersion pulmonary edema (IPE) affects divers and swimmers across the age and fitness spectrum, including young, trained individuals, indicating that mechanical factors act alongside any car

T Thibaut Prevautel

Preimplantation genetic testing to determine polygenic disease risk: Will we know when to stop?

JBRA Assist Reprod. 2026 Sep 28. doi: 10.5935/1518-0557.20260061. Online ahead of print.ABSTRACTRecent advances in genomics technologies have facilitated the introduction of new tools that broaden the scope of applications for genetic data. Preimplantation genetic testing using polygenic risk scores

D Daniela Paes de Almeida Ferreira Braga

Cardiovascular Mortality In Mental Health Disorders: A Population-Based Analysis of US Mortality Data, 1999-2024

Cardiol Rev. 2026 Sep 25. doi: 10.1097/CRD.0000000000001480. Online ahead of print.ABSTRACTMental health disorders are linked with increased cardiovascular disease and mortality risk, yet national trends in cardiovascular mortality among US adults with mental health disorders remain incompletely cha

M Muhammad Shaheer Bin Faheem

Deep phenotyping of EHMT1 ankyrin repeat domain missense variants in Kleefstra syndrome by multi-tiered structural genomics analyses at atomic resolution

Hum Mol Genet. 2026 Sep 11;35(20):ddag094. doi: 10.1093/hmg/ddag094.ABSTRACTEHMT1 is a lysine methyltransferase that writes and reads histone methylation marks to repress transcription. Deleterious mutations in EHMT1 cause Kleefstra syndrome (KLEFS1; OMIM #610253), a congenital neurodevelopmental di

K Karina L Bursch

Mild caloric restriction accelerates atherosclerosis via dysregulated cholesterol homeostasis and lipogenesis in HCHF-fed ApoE-deficient mice

JCI Insight. 2026 Sep 22:e202798. doi: 10.1172/jci.insight.202798. Online ahead of print.ABSTRACTRecent ACC/AHA guidelines recommend ≥5% weight loss over six months to reduce cardiovascular risk in obesity. However, some populations paradoxically exhibit increased cardiovascular disease (CVD) follow

Y Yun Zhu

From Hippocrates to Biologics, The Evolving History of Pericarditis: A Review

Circulation. 2026 Sep 29;154(13):1265-1275. doi: 10.1161/CIRCULATIONAHA.126.079230. Epub 2026 Sep 28.ABSTRACTPericarditis remains a common and clinically relevant cardiovascular condition whose diagnosis and management have evolved substantially over time. Understanding this historical progression p

A Astefanos Al-Dalakta

2026 AHA/ACC/ACS/ASNC/HRS/SCA/SCCT/SCMR/SVM Guideline for Perioperative Cardiovascular Management for Noncardiac Surgery: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines

Circulation. 2026 Sep 29;154(13):e413-e504. doi: 10.1161/CIR.0000000000001472. Epub 2026 Sep 28.ABSTRACTAIM: The "2026 AHA/ACC/ACS/ASNC/HRS/SCA/SCCT/SCMR/SVM Guideline for Perioperative Cardiovascular Management for Noncardiac Surgery" provides recommendations to guide clinicians in the perioperativ

W Writing Committee Members

Predicted Heart Mass and Severe Primary Graft Dysfunction in Donation After Circulatory Death Heart Transplant

Clin Transplant. 2026 Oct;40(10):e70689. doi: 10.1111/ctr.70689.ABSTRACTBACKGROUND: Donation after circulatory death (DCD) has expanded the US heart donor pool yet carries a higher risk of severe primary graft dysfunction (PGD) for recipients compared to donation after brain death (DBD). This study

J Joseph Barile

Stroke Prevention in the Longevity Era: An Integrated Framework for Cerebrovascular and Biological Aging

No abstractStroke. 2026 Oct;57(10):3213-3218. doi: 10.1161/STROKEAHA.126.056919. Epub 2026 Sep 28.NO ABSTRACTPMID:42804559 | DOI:10.1161/STROKEAHA.126.056919

G Gustavo Saposnik

Prehospital Stroke Treatment Trials in Conventional EMS Settings: An Expert Consensus Statement on Operational, Ethical, and Technological Priorities

Stroke. 2026 Oct;57(10):3200-3212. doi: 10.1161/STROKEAHA.126.056028. Epub 2026 Sep 28.ABSTRACTPrehospital stroke trials enable assessments of ultraearly administration of treatments and management strategies, but face unique challenges in their design, conduct, and analysis. We outline important co

N Nishita Singh

From wrist to research: Harnessing smartwatch data for equitable cardiovascular research

PLoS Med. 2026 Sep 28;23(9):e1005260. doi: 10.1371/journal.pmed.1005260. eCollection 2026 Sep.ABSTRACTCardiovascular disease is a leading cause of death, and progress in reducing mortality has stalled, calling for more research. An opportunity lies in harnessing cardiovascular data from smartwatches

M Manpreet Kaur

Effects of blood flow restriction combined with visual feedback training on lower limb function and the serum levels of BDNF and VEGF in patients with stroke

PLoS One. 2026 Sep 28;21(9):e0358740. doi: 10.1371/journal.pone.0358740. eCollection 2026.ABSTRACTOBJECTIVE: This study aimed to investigate the effects of blood flow restriction training (BFRT) combined with visual feedback training (VFT) on lower limb function and serum levels of brain-derived neu

H Hai Jiang

Physical activity interventions for cardiometabolic and psychosocial outcomes in people living with HIV in sub Saharan Africa: A systematic review

PLOS Glob Public Health. 2026 Sep 28;6(9):e0007070. doi: 10.1371/journal.pgph.0007070. eCollection 2026.ABSTRACTAntiretroviral therapy (ART) has extended the lifespan of people living with HIV (PWH), resulting in a growing burden of cardiometabolic disease (CMD) associated with chronic HIV infection

S Smart Z Mabweazara

Leveraging millet's potential to mitigate metabolic syndrome: a comprehensive approach for managing lifestyle disorders

Crit Rev Food Sci Nutr. 2026 Sep 28:1-29. doi: 10.1080/10408398.2026.2737065. Online ahead of print.ABSTRACTThe "World Health Organization" predicts that non-communicable illnesses affect 41 million people globally, with cardiovascular disease accounting for 17.9 million and diabetes 2 million. The

S Saikat Mazumder

Home-based lower leg heat therapy in postmenopausal women with hypertension. I. Effects on blood pressure

J Appl Physiol (1985). 2026 Sep 28. doi: 10.1152/japplphysiol.90170.2026. Online ahead of print.ABSTRACTDespite conventional drug treatment for hypertension, postmenopausal women in the U.S. maintain relatively poor blood pressure (BP) control rates. Alternatives, such as heat therapy, represent pro

J John D Akins

Reawakening ApoB-Specific Immunity in Atherosclerotic Cardiovascular Disease: P210-Conjugated Nanoparticles Restore Impaired CD4+ T Cell Responses

No abstractAm J Physiol Heart Circ Physiol. 2026 Sep 28. doi: 10.1152/ajpheart.90037.2026. Online ahead of print.NO ABSTRACTPMID:42804371 | DOI:10.1152/ajpheart.90037.2026

D Dr Randa Salah Gomaa Mahmoud

Response to Dobutamine in Septic Shock With Myocardial Dysfunction: A Single-Center Retrospective Study

Crit Care Explor. 2026 Sep 25;8(10):e1487. doi: 10.1097/CCE.0000000000001487. eCollection 2026 Oct 1.ABSTRACTIMPORTANCE: Dobutamine is recommended for septic shock with myocardial dysfunction and persistent hypoperfusion despite preload and mean arterial pressure optimization; however, supporting ev

M Marwa Tarbaghia

Acute Respiratory Failure Survivors' Perspectives on Patient-Centered Communication: A Mixed Methods Study

Crit Care Explor. 2026 Sep 25;8(10):e1492. doi: 10.1097/CCE.0000000000001492. eCollection 2026 Oct 1.ABSTRACTIMPORTANCE: Many acute respiratory failure (ARF) survivors develop psychiatric sequelae. Inpatient psychologic distress is an important risk factor.OBJECTIVES: Evaluate ARF survivors' perspec

D Diana C Bouhassira

Cardiovascular risk factors and regional neuropathology in autopsy-confirmed Alzheimer disease

J Neuropathol Exp Neurol. 2026 Sep 28:nlag081. doi: 10.1093/jnen/nlag081. Online ahead of print.ABSTRACTCardiovascular risk factors are implicated in Alzheimer disease (AD) progression and its neuropathological hallmarks but their specific contributions to regional brain pathology within AD remain u

D David Garcia

Presenting Symptoms and Antibiotic Timing Among Hospitalized Adults With Presumed Sepsis

JAMA Netw Open. 2026 Sep 1;9(9):e2635575. doi: 10.1001/jamanetworkopen.2026.35575.ABSTRACTIMPORTANCE: Timely antibiotics are associated with reduced sepsis mortality, particularly among patients with hypotension; however, antibiotic delays are common in practice. Presenting symptoms may influence an

A Anna Conlon

Rural Hospital Closures and Mortality From Time-Sensitive Conditions in Texas

JAMA Netw Open. 2026 Sep 1;9(9):e2636325. doi: 10.1001/jamanetworkopen.2026.36325.ABSTRACTIMPORTANCE: Rural hospital closures in the US have accelerated since 2010, with Texas experiencing more rural closures than any other state. Whether closures are associated with population-level mortality remai

M Mark A Poisler

Cardiovascular Disease Risk Among Childhood and Young Adult Cancer Survivors: A Systematic Review and Meta-Analysis

JAMA Pediatr. 2026 Sep 28. doi: 10.1001/jamapediatrics.2026.4478. Online ahead of print.ABSTRACTIMPORTANCE: There is a growing population of childhood, adolescent, and young adult (CAYA) cancer survivors (younger than 40 years). Cardiovascular disease (CVD) becomes one of the primary sequelae during

C Chi Shu