Baseline, repeated-measure burden, and two-time-point patterns of the triglyceride-glucose index-visceral lipid ratio (TyG-VLR) and incident cardiovascular disease in cardiovascular-kidney-metabolic (CKM) syndrome stages 0-3: a longitudinal China Health and Retirement Longitudinal Study (CHARLS) analysis

Cardiovasc Diabetol. 2026 Jul 25;25(1):221. doi: 10.1186/s12933-026-03302-0.ABSTRACTBACKGROUND: Cardiovascular-kidney-metabolic (CKM) syndrome stages 0-3 define a population without overt clinical cardiovascular disease (CVD) but with accumulating metabolic, adiposity, lipid, and kidney-related risk

A Ao-Men Lu

Type 2 diabetes is associated with clinical progression of aortic stenosis: a nationwide retrospective study in Sweden

Sci Rep. 2026 Aug 8;16(1):24550. doi: 10.1038/s41598-026-64970-2.ABSTRACTPatients with type 2 diabetes mellitus (T2DM) have elevated risk for aortic stenosis (AS). The impact of diabetes on prognosis and clinical progression in AS is not well documented. In this study we try to assess if patients wi

S Silvana Kontogeorgos

External validation of a top-ranked model from the RSNA pulmonary embolism detection challenge: assessment of generalizability

To externally validate the RSNA 2020 challenge 2^(nd)-place deep-learning (DL) algorithm for detecting pulmonary embolism (PE) on computed tomography pulmonary angiography (CTPA) scans with additional focus on subsegmental-only PEs (SSPE). Between 2015 and 2022 1,038 CTPAs were retrospectively enrol

P Patricia Hahlbohm

Association between lipoprotein (a) levels and cardiac allograft vasculopathy among heart transplant recipients: Insights from a single-center cohort

J Clin Lipidol. 2026 Jul 20:S1933-2874(26)00456-3. doi: 10.1016/j.jacl.2026.07.024. Online ahead of print.ABSTRACTBACKGROUND: Serum lipoprotein (a) [Lp(a)] is a causal risk factor for atherosclerotic cardiovascular disease in the general population, but its association with cardiac allograft vasculo

D Daniela Bacich

Food additive and naturally occurring glutamate and risk of cardiovascular diseases in the NutriNet-Sante prospective cohort

Am J Clin Nutr. 2026 Aug 8:101462. doi: 10.1016/j.ajcnut.2026.101462. Online ahead of print.ABSTRACTBACKGROUND: The potential cardiac toxicity of glutamate is debated and has been suggested by some epidemiological and experimental studies. To our knowledge, none investigated the links between both n

A Anaïs Hasenböhler

Occurrence of Dysphagia in Patients Admitted to a Department of Pulmonary Medicine

Clin Nutr ESPEN. 2026 Aug 8:105016. doi: 10.1016/j.clnesp.2026.105016. Online ahead of print.ABSTRACTBACKGROUND: Awareness of dysphagia and its clinical implications is increasing, yet its occurrence and impact among patients in Departments of Pulmonary Medicine remain underexplored. This study aims

H Helle Vendel Petersen

Trends in the association between diabetes duration and cardiovascular events: a population-based cohort study

Diabetes Res Clin Pract. 2026 Aug 8:113491. doi: 10.1016/j.diabres.2026.113491. Online ahead of print.ABSTRACTWe conducted a population-based study examining the associations of diabetes duration and prior cardiovascular disease (CVD) with subsequent cardiovascular events. We demonstrate that diabet

T Tharsan Kanagalingam

Aminolevulinic Acid Photodynamic Therapy for Extensive Genital Extramammary Paget Disease in Older Patients: A Retrospective Clinical Case Series

Photodiagnosis Photodyn Ther. 2026 Aug 8:105607. doi: 10.1016/j.pdpdt.2026.105607. Online ahead of print.ABSTRACTBACKGROUND: Extramammary Paget disease (EMPD) involving the genital and anogenital region is difficult to manage when lesions are extensive, chronic, or located across functionally sensit

X Xu Ji

The effects of Metformin on myocardial ischemia and reperfusion injury in diabetic rats and its potential mechanism

Cell Signal. 2026 Aug 8:112802. doi: 10.1016/j.cellsig.2026.112802. Online ahead of print.ABSTRACTDiabetic cardiovascular disease remains the leading cause of mortality in patients with diabetes, underscoring the urgent need for effective therapeutic strategies to improve clinical outcomes and preve

Y Yunna Ma

Therapy-Related Acute Lymphoblastic Leukemia with Plasmablastic Morphology after Myeloma: a Pitfall

Clin Lab. 2026 Aug 1;72(8). doi: 10.7754/Clin.Lab.2025.250917.ABSTRACTBACKGROUND: Therapy-related acute lymphoblastic leukemia (t-ALL) after multiple myeloma (MM) treatment is a rare complication linked to lenalidomide and autologous stem cell transplantation (ASCT). Diagnosing t-ALL vs. MM relapse

H Huimei Ge

Proposed Solutions for a Multiple Myeloma Case with Unobtainable Serum

Clin Lab. 2026 Aug 1;72(8). doi: 10.7754/Clin.Lab.2025.250834.ABSTRACTBACKGROUND: Multiple myeloma (MM) is a plasma cell malignancy characterized by monoclonal protein secretion. Excessive immunoglobulin production increases blood viscosity, impairing serum separation and complicating laboratory ana

Z Zeliha Kocaismail

Digital twins in geriatrics and gerontology: Applications, challenges, and future directions

Arch Gerontol Geriatr. 2026 Aug 3;150:106371. doi: 10.1016/j.archger.2026.106371. Online ahead of print.ABSTRACTBACKGROUND: The global population is ageing at an unprecedented rate, creating substantial pressures on healthcare systems to deliver personalised, proactive, and cost-effective care for o

G Grace Oluwatoyin Faronbi

Postural and workflow impacts from the implementation of a cardiovascular surgery/procedure instrument platform within an image-guided interventional environment

Am J Surg. 2026 Jul 31;261:117171. doi: 10.1016/j.amjsurg.2026.117171. Online ahead of print.ABSTRACTBACKGROUND/OBJECTIVES: Image-guided surgical procedures have spatial constraints that complicate workflow, contributing to repetitive awkward turning and leaning postures. These postures, coupled wit

Y Yifan Li

Digital nudges for cardiovascular health: A scoping review through the lens of dual-process theory

Int J Nurs Stud. 2026 Aug 3;183:105657. doi: 10.1016/j.ijnurstu.2026.105657. Online ahead of print.ABSTRACTBACKGROUND: Digital nudging uses technology-based modifications to subtly influence health-related decisions without restricting choice. However, no review has systematically examined digital n

X Xue Wang

Mosaic Loss of Y Chromosome and Risks of Peripheral Arterial and Aortic Diseases

JACC Adv. 2026 Aug 8;5(9):103113. doi: 10.1016/j.jacadv.2026.103113. Online ahead of print.ABSTRACTBACKGROUND: Mosaic loss of Y chromosome (mLOY) is the most prevalent somatic mutation in males associated with aging.OBJECTIVES: This study aimed to test the association of mLOY with new-onset peripher

Z Zhiwei Zeng

MiR-485-5p targets RGS4 to promote angiogenesis in lower limb ischemia by activating VEGFR-2/AKT/ERK1/2 signaling

Life Sci. 2026 Aug 8:124626. doi: 10.1016/j.lfs.2026.124626. Online ahead of print.ABSTRACTAngiogenesis is critical for post-ischemic tissue repair. Although miR-485-5p is highly expressed in vascular tissues and RGS4 regulates angiogenesis, their specific roles under hypoxia remain largely unknown.

M Mengting Li

Biallelic titin truncation disrupts sarcomere assembly and function in patient-derived iPSC-cardiomyocytes

J Mol Cell Cardiol. 2026 Aug 8:S0022-2828(26)00119-7. doi: 10.1016/j.yjmcc.2026.08.001. Online ahead of print.ABSTRACTBiallelic titin truncation variants (TTNtvs) are linked to severe cardiac and skeletal muscle diseases, due to unclear mechanisms. Using induced pluripotent stem cell-derived cardiom

M Magnhild Sekse Erdal

Scutellarin alleviates obesity-induced renal fibrosis by regulating ITGA9 to suppress FAK/PI3K/AKT signaling

Phytomedicine. 2026 Aug 3;160:158681. doi: 10.1016/j.phymed.2026.158681. Online ahead of print.ABSTRACTObesity exacerbates pathological injury in chronic kidney disease and ultimately leads to end-stage renal fibrosis. Extensive studies have demonstrated that scutellarin (SCU), the major active comp

W Wei Li

Heat-protective behavior in pregnancy: Extending Protection Motivation Theory with environmental and social factors

Soc Sci Med. 2026 Aug 1;406:119653. doi: 10.1016/j.socscimed.2026.119653. Online ahead of print.ABSTRACTOBJECTIVE: Pregnant women are particularly vulnerable to heat-related health risks, yet little is known about heat-protective behavioral adaptation during pregnancy. We extended Protection Motivat

H Hannah Lintener

Depressive symptoms in the association between herpes zoster and heart disease in middle-aged and older adults: A longitudinal cohort study

Acta Psychol (Amst). 2026 Aug 8;269:107601. doi: 10.1016/j.actpsy.2026.107601. Online ahead of print.ABSTRACTBACKGROUND: Herpes zoster (HZ) has been linked to elevated cardiovascular risk, but the mechanisms remain unclear. Depressive symptoms, particularly specific domains of symptoms, may show sta

Z Zirui Huang

Comparative risk of postoperative complications in ulcerative colitis patients following preoperative advanced therapies: a network meta-analysis with meta-regression

J Crohns Colitis. 2026 Aug 5;20(8):jjag111. doi: 10.1093/ecco-jcc/jjag111.ABSTRACTBACKGROUND: The expanding use of biologic and small-molecule therapies for ulcerative colitis (UC) has raised concerns regarding perioperative safety. We conducted a network meta-analysis to compare short-term postoper

M Mohammad Al Hayek

Trends in glucagon-like peptide-1 receptor agonist utilization and expenditure in Croatia

J Int Med Res. 2026 Aug;54(8):3000605261470651. doi: 10.1177/03000605261470651. Epub 2026 Aug 8.ABSTRACTIntroductionGlucagon-like peptide-1 receptor agonists (GLP-1 RAs) have transformed the management of type 2 diabetes and obesity by improving glycemic control, promoting weight loss, and reducing

A Andrej Belančić

Association between galectin-3 and echocardiographic changes in hospitalized patients with coronavirus disease 2019: A retrospective observational study

J Int Med Res. 2026 Aug;54(8):3000605261471690. doi: 10.1177/03000605261471690. Epub 2026 Aug 8.ABSTRACTObjectiveTo assess the association between serum galectin-3 levels and echocardiographic changes in hospitalized patients with coronavirus disease 2019 across different disease severities and stag

N Nana Egiashvili

Development and external validation of an online interpretable machine-learning model for predicting delirium risk in acute heart failure

J Int Med Res. 2026 Aug;54(8):3000605261472037. doi: 10.1177/03000605261472037. Epub 2026 Aug 8.ABSTRACTObjectiveDelirium is a frequent complication in acute heart failure and is associated with poor outcomes in the intensive care unit. Machine learning methods can leverage high-dimensional clinical

W Weijie Huang