Acta Pharmacol Sin. 2026 Jun 3. doi: 10.1038/s41401-026-01830-9. Online ahead of print.ABSTRACTCardiovascular disease (CVD) remains the leading cause of morbidity and mortality worldwide, and its progression is closely linked to mitochondrial dysfunction in cardiomyocytes. Given the high energy dema
Sci Rep. 2026 Jun 3. doi: 10.1038/s41598-026-56432-6. Online ahead of print.ABSTRACTPulmonary hypertension (PH) is a heterogeneous condition with variable prognosis across World Health Organization (WHO) subtypes. The fasting blood glucose to high-density lipoprotein cholesterol (FBG/HDL-C) ratio ha
Pediatr Res. 2026 Jun 3. doi: 10.1038/s41390-026-05130-0. Online ahead of print.ABSTRACTBACKGROUND: Preterm birth has long-term consequences including higher cardiovascular disease risk. We previously reported the effect of an exercise intervention on cardiorespiratory fitness in young adults born p
Eur J Hum Genet. 2026 Jun 3. doi: 10.1038/s41431-026-02145-3. Online ahead of print.ABSTRACTThoracic aortic dissection (TAD) is a life-threatening condition with a significant genetic contribution. This study evaluated the clinical implications of diagnostic screening of 368 TAD patients for (likely
Sci Rep. 2026 Jun 3. doi: 10.1038/s41598-026-56009-3. Online ahead of print.ABSTRACTPatients with end-stage renal disease (ESRD) undergoing hemodialysis (HD) often exhibit substantial impairments in aerobic capacity and skeletal muscle oxidative function, contributing to physical deconditioning and
Sci Rep. 2026 Jun 4. doi: 10.1038/s41598-026-54659-x. Online ahead of print.ABSTRACTSeveral thermogenic pathways have been described in adipose tissue, including calcium-mediated thermogenesis in beige adipocytes. We have previously shown that adipocyte-specific deletion of the RNA binding protein h
High Blood Press Cardiovasc Prev. 2026 Jun 4. doi: 10.1007/s40292-026-00806-4. Online ahead of print.ABSTRACTINTRODUCTION: Voluntary users of mobile health (mHealth) apps indicate an interest in lowering cardiovascular disease (CVD) risk. It is unclear by which extent blood pressure (BP) or choleste
Infect Dis Ther. 2026 Jun 3. doi: 10.1007/s40121-026-01362-z. Online ahead of print.ABSTRACTINTRODUCTION: Patients with type 2 diabetes mellitus (T2DM) are at increased risk of post-acute sequelae after COVID-19 (PASC). Sodium-glucose cotransporter-2 inhibitors (SGLT2i) and metformin may have system
Commun Med (Lond). 2026 Jun 3. doi: 10.1038/s43856-026-01697-1. Online ahead of print.ABSTRACTBACKGROUND: While loss of Y chromosome (LOY), a common somatic alteration with aging, has been associated with cardiovascular diseases, its specific impact on ST-segment elevation myocardial infarction (STE
Clin Neuroradiol. 2026 Jun 3. doi: 10.1007/s00062-026-01673-1. Online ahead of print.ABSTRACTBACKGROUND: Microplastics (MPs) have been detected in human tissues and implicated in vascular injury in preclinical models, but evidence on circulating MPs in humans is scarce. Surgical and autopsy samples
NPJ Genom Med. 2026 Jun 3. doi: 10.1038/s41525-026-00586-9. Online ahead of print.ABSTRACTAtrial cardiomyopathy, which often comes with underlying genetic defects, has been recognized as a possible substrate of atrial fibrillation. MYH6 encodes α-myosin heavy chain (α-MHC), predominantly expressed i
Diabetes Obes Metab. 2026 Jun 3. doi: 10.1111/dom.70906. Online ahead of print.ABSTRACTAIMS: Chronic kidney disease (CKD) is a common complication of Type 2 diabetes that frequently co-occurs with cardiovascular disease. We aimed to characterise CKD in adults with Type 2 diabetes, quantify its preva
Diabetes Obes Metab. 2026 Jun 3. doi: 10.1111/dom.70924. Online ahead of print.ABSTRACTAIMS: Heart failure (HF) is among the most costly and prevalent complications of type 2 diabetes (T2D), with annual incremental healthcare costs reaching US$12800 in Hong Kong. We evaluated the cost-effectiveness
Intern Med. 2026 Jun 4. doi: 10.2169/internalmedicine.7239-26. Online ahead of print.ABSTRACTA 46-year-old Japanese man with nonobstructive hypertrophic cardiomyopathy harboring a heterozygous PSEN1 c.367G>A (p.Glu123Lys) variant experienced sudden cardiac arrest due to ventricular fibrillation at 5
Expert Rev Hematol. 2026 Jun 3. doi: 10.1080/17474086.2026.2683032. Online ahead of print.ABSTRACTINTRODUCTION: Patients with polycythemia vera (PV) can experience thromboembolism (TE) and progress to myelofibrosis, acute myeloid leukemia, or myelodysplastic syndromes. Treatments for PV, particularl
BMJ Open. 2026 Jun 3;16(6):e117719. doi: 10.1136/bmjopen-2026-117719.ABSTRACTOBJECTIVES: To examine whether the use of a venous access-site closure device is associated with the occurrence of postoperative nausea and vomiting (PONV) after atrial fibrillation (AF) ablation under propofol sedation.DES
Obstet Gynecol Clin North Am. 2026 Jun;53(2):297-310. doi: 10.1016/j.ogc.2025.12.005. Epub 2026 Feb 6.ABSTRACTTransgender and gender diverse (TGD) people weather stigma and discrimination and experience significant barriers to preventive health care, contributing to disproportionate burdens of chron
Vitam Horm. 2026;132:79-92. doi: 10.1016/bs.vh.2026.02.001. Epub 2026 May 11.ABSTRACTCushing´s syndrome (CS) is a heterogeneous disorder characterized by chronic exposure to cortisol excess, leading to significant metabolic and cardiovascular complications. Timely diagnosis is crucial to reduce morb
Vitam Horm. 2026;132:317-344. doi: 10.1016/bs.vh.2026.02.006. Epub 2026 Mar 9.ABSTRACTEndogenous Cushing's syndrome (CS) is characterized by chronic glucocorticoid excess that drives a severe cardiometabolic phenotype responsible for most morbidity and mortality associated with the disorder. Cortiso
Vitam Horm. 2026;132:1-55. doi: 10.1016/bs.vh.2026.04.001. Epub 2026 May 15.ABSTRACTCushing's syndrome (CS) presents with a constellation of features reflecting chronic glucocorticoid excess. Hallmarks-central adiposity with thin extremities, dorsocervical and supraclavicular fat pads, round facies
Cardiovasc Pathol. 2026 Jun 2:107836. doi: 10.1016/j.carpath.2026.107836. Online ahead of print.ABSTRACTBACKGROUND: Previous post-mortem studies in victims of intoxication have typically focused on toxicological and biochemical analyses. This study aimed to assess the prevalence and types of cardiov
Can J Cardiol. 2026 Jun 2:S0828-282X(26)00516-7. doi: 10.1016/j.cjca.2026.05.020. Online ahead of print.ABSTRACTPatients with systemic lupus erythematosus (SLE) are at increased risk of a wide range of cardiovascular manifestations, which contribute substantially to morbidity and mortality. Multimod
Environ Toxicol Pharmacol. 2026 Jun 2:105055. doi: 10.1016/j.etap.2026.105055. Online ahead of print.ABSTRACTAir pollution is recognized as a major environmental risk factor, with growing evidence that it affects the central nervous system in addition to the respiratory and cardiovascular systems. E
Clin Chim Acta. 2026 Jun 2:121139. doi: 10.1016/j.cca.2026.121139. Online ahead of print.ABSTRACTChronic kidney disease (CKD) is increasingly recognized not only as a state of declining renal function but also as a complex systemic disorder characterized by a persistent, low-grade inflammatory state
