Curr Med Res Opin. 2026 Oct 14:1-11. doi: 10.1080/03007995.2026.2743357. Online ahead of print.ABSTRACTBACKGROUND: The Aggregate Index of Systemic Inflammation (AISI) is a potential cardiovascular risk indicator. Its association with contemporaneous myocardial injury in coronary heart disease (CHD)
Acta Neuropsychiatr. 2026 Oct 14;38:e56. doi: 10.1017/neu.2026.10098.ABSTRACTTreatment-resistant mood disorders, including major depressive disorder (MDD) and bipolar disorder (BD), remain a significant clinical challenge. A confluence of emerging evidence implicates chronic low-grade inflammation i
Expert Opin Pharmacother. 2026 Oct 14. doi: 10.1080/14656566.2026.2749643. Online ahead of print.ABSTRACTINTRODUCTION: Metabolic dysfunction-associated steatotic liver disease and metabolic dysfunction-associated steatohepatitis (MASLD/MASH) pharmacotherapy is changing rapidly after the approval of
Food Funct. 2026 Oct 14. doi: 10.1039/d6fo04204j. Online ahead of print.ABSTRACTBackground: The EAT-Lancet diet, designed for planetary and human health, has been associated with lower risk of cardiovascular disease (CVD) and mortality. Identifying plasma proteins associated with the EAT-Lancet diet
Ann Pharmacother. 2026 Oct 14:10600280261494015. doi: 10.1177/10600280261494015. Online ahead of print.ABSTRACTOBJECTIVE: This article describes pharmacology, pharmacokinetics, safety, and efficacy data of enlicitide, the first Food and Drug Administration (FDA)-approved oral proprotein convertase s
Biomed Environ Sci. 2026 Sep 20;39(9):1115-1130. doi: 10.3967/bes2026.094.ABSTRACTCardiovascular diseases (CVDs) are the leading causes of death worldwide, have a growing disease burden, and present multiple challenges for precision management. Clinical Decision Support Systems (CDSS) are tools that
Biomed Environ Sci. 2026 Sep 20;39(9):1081-1092. doi: 10.3967/bes2026.084.ABSTRACTOBJECTIVE: To investigate the epidemiology and risk factors for chronic urticaria (CU) in Chinese adults with cardiometabolic diseases (CMDs), and its effect on CMD recognition and management.METHODS: We conducted a na
Pediatr Int. 2026 Jan-Dec;68(1):e70585. doi: 10.1111/ped.70585.ABSTRACTBACKGROUND: To evaluate temporal changes in serum interleukin-40 (IL-40), hypoxia-inducible factor-1 alpha (HIF-1α), and procalcitonin (PCT) levels between early and post-rewarming measurements in neonates with moderate-to-severe
Future Cardiol. 2026 Oct 14:1-14. doi: 10.1080/14796678.2026.2746297. Online ahead of print.ABSTRACTBACKGROUND: Coronary artery disease (CAD) is a leading cause of morbidity and mortality worldwide, affecting approximately 197 million people and causing over 9 million deaths annually. Although percu
Diabetes Obes Metab. 2026 Oct 14. doi: 10.1111/dom.71427. Online ahead of print.ABSTRACTAIMS: To identify representative cardiometabolic biomarkers and examine how individual biomarkers and combined biomarker burden are associated with transition-specific progression of cardio-renal-metabolic multim
Nepal J Ophthalmol. 2025 Jul;17(34):57-67. doi: 10.3126/nepjoph.v17i34.86992.ABSTRACTINTRODUCTION: Diabetic retinopathy is a leading cause of vision loss in Fiji, where treatment options beyond panretinal photocoagulation (PRP) remain limited. In this context, evaluating longterm outcomes of PRP can
Nepal J Ophthalmol. 2025 Jul;17(34):5-16. doi: 10.3126/nepjoph.v17i34.69532.ABSTRACTINTRODUCTION: Ranibizumab biosimilar (RbB) has emerged as a cost-effective treatment modality. There is paucity of literature on optical coherence tomography angiography (OCTA) parameters following use of RbB in DME.
Nepal J Ophthalmol. 2026 Jan;18(35):87-95. doi: 10.3126/nepjoph.v18i35.75209.ABSTRACTINTRODUCTION: Diabetic retinopathy is on the rise and understanding mechanisms of retinal neurodegeneration in diabetes mellitus will help in halting retinopathy.OBJECTIVE: The study was done to assess the retinal n
Nepal J Ophthalmol. 2026 Jan;18(35):23-30. doi: 10.3126/nepjoph.v18i35.82606.ABSTRACTINTRODUCTION: Diabetic retinopathy (DR) is usually treated with Anti-vascular endothelial growth factor (anti-VEGF) agents. Ranibizumab is an approved drug for ocular use, while bevacizumab has also been introduced
Eur Heart J. 2026 Oct 14:ehag708. doi: 10.1093/eurheartj/ehag708. Online ahead of print.ABSTRACTCardiogenic shock (CS) remains a heterogeneous syndrome associated with persistently high mortality despite advances in temporary mechanical circulatory support. One recent randomized controlled trial sug
Eur Heart J Cardiovasc Imaging. 2026 Oct 14:jeag285. doi: 10.1093/ehjci/jeag285. Online ahead of print.ABSTRACTAIMS: The prognostic significance of late gadolinium enhancement (LGE)-detected replacement myocardial fibrosis in aortic regurgitation (AR) remains incompletely understood. This study aims
Egypt J Immunol. 2026 Oct;33(4):54-63. doi: 10.55133/eji.330405.ABSTRACTHypertension (HTN) is the leading modifiable risk factor of cardiovascular diseases. Implicated immunological mechanisms are of great interest nowadays. This study aimed to assess the role of B cells by measuring serum immunoglo
ChemMedChem. 2026 Oct 14;21(19):e70506. doi: 10.1002/cmdc.70506.ABSTRACTThis review provides an overview of recent advances in the development of multitarget drugs (MTDs) for cardiac diseases, with a particular focus on emerging molecular scaffolds and their pharmacological properties. We discuss th
No abstractASAIO J. 2026 Oct 14. doi: 10.1097/MAT.0000000000002884. Online ahead of print.NO ABSTRACTPMID:42870346 | DOI:10.1097/MAT.0000000000002884
J Chin Med Assoc. 2026 Oct 14. doi: 10.1097/JCMA.0000000000001436. Online ahead of print.ABSTRACTBACKGROUND: Stenosis is a common complication of arteriovenous access (AV), for which percutaneous transluminal angioplasty (PTA) is a well-established intervention. Nevertheless, balloon dilation common
J Cardiovasc Imaging. 2026 Oct 13;34(1):39. doi: 10.1186/s44348-026-00086-5.ABSTRACTBACKGROUND: Ascending aortic diameter guides intervention for thoracic aneurysms. Many patients with acute type A aortic dissection (ATAAD) present with ascending aortic diameters below 5.5 cm, rendering diameter an
BMC Gastroenterol. 2026 Oct 12;26(1):641. doi: 10.1186/s12876-026-05422-z.ABSTRACTBACKGROUND: Low-dose aspirin use is associated with reduced CRC incidence and CRC-related mortality. A similar association with P2Y12 inhibitor use remains uncertain. We investigated whether the use of P2Y12 inhibitors
Mol Neurobiol. 2026 Oct 14;63(1):964. doi: 10.1007/s12035-026-06257-1.ABSTRACTStroke remains one of the leading causes of death and disability worldwide, with neuroinflammation playing a critical role in its pathogenesis. The cyclic GMP-AMP synthase-stimulator of interferon genes (cGAS-STING) pathwa
Cardiovascular disease (CVD) is the leading cause of death worldwide¹, yet gaps remain for underrepresented populations in CVD research and clinical guidelines. The LGBTQIA+ community comprises 7% of the U.S. population², and evidence suggests a higher predisposition to CVD from increased psychosoci
