Intrapartum recognition and management of fetal inflammation

Eur J Pediatr. 2026 Jan 15;185(2):81. doi: 10.1007/s00431-025-06738-w.ABSTRACTIntra-amniotic inflammation and infection are common intrapartum conditions at term and represent a major cause of fetal and neonatal morbidity independent of hypoxia. These conditions trigger the fetal inflammatory respon

E Elvira di Pasquo

The modifying effect of chronological age on the predictive value of vascular aging indicators for the long-term cardiovascular events risk

Hypertens Res. 2026 Jan 15. doi: 10.1038/s41440-025-02503-6. Online ahead of print.ABSTRACTWhether chronological age affects the ability of vascular aging indicators to predict cardiovascular events risk remains unknown. This study sought to examine whether the predictability of vascular aging indic

T Tianhui Dong

Fractional flow reserve-guided percutaneous coronary intervention versus medical therapy for stable coronary artery disease: long-term results of the FAME 2 trial

Nat Med. 2026 Jan 15. doi: 10.1038/s41591-025-04132-5. Online ahead of print.ABSTRACTIn patients with stable coronary artery disease (CAD), the long-term benefits of revascularization over medical therapy remain unclear. In the Fractional Flow Reserve versus Angiography for Multivessel Evaluation 2

C Carlos Collet

Dialysis versus conservative kidney management in older adults: why one size does not fit all

Int Urol Nephrol. 2026 Jan 15. doi: 10.1007/s11255-026-05009-3. Online ahead of print.ABSTRACTBACKGROUND: As the global population ages, an increasing number of older adults progress to end-stage kidney disease (ESKD). In this population, frailty, multimorbidity, and functional decline often limit t

D Dragos Scripcariu

Outcomes in Patients with Psoriasis Following Apremilast Treatment: Results from the German Psoriasis Registry PsoBest

Dermatol Ther (Heidelb). 2026 Jan 15. doi: 10.1007/s13555-025-01631-8. Online ahead of print.ABSTRACTINTRODUCTION: The German national psoriasis registry PsoBest collects long-term data on the effectiveness, safety, and tolerability of systemic treatments for psoriatic disease. Here, we describe pat

M Matthias Augustin

Hemoglobin glycation index predicts mortality in intracerebral hemorrhage: a nonlinear threshold effect

Neurol Sci. 2026 Jan 15;47(1):166. doi: 10.1007/s10072-025-08700-y.ABSTRACTBACKGROUND: The Hemoglobin Glycation Index (HGI), integrating acute and chronic glycemic dysregulation, may reflect metabolic state in critical illness. We aimed to evaluate whether HGI predicts 30-day mortality in intracereb

S Shuwen Sun

Implementation of post-mortem examinations within a large population-based cohort: results from the Hamburg City Health Study

Clin Res Cardiol. 2026 Jan 15. doi: 10.1007/s00392-025-02829-8. Online ahead of print.ABSTRACTBACKGROUND: Full post-mortem examinations (conventional autopsies) are a valuable tool for understanding disease mechanisms but are commonly rare, especially in epidemiological research. This study aimed to

M Maria Luisa Benesch Vidal

CT-derived density of intracranial arteriosclerosis: a population-based cohort study

Eur Radiol. 2026 Jan 15. doi: 10.1007/s00330-025-12180-1. Online ahead of print.ABSTRACTBACKGROUND: The CT-derived density of coronary artery calcification is increasingly associated with the risk of ischemic heart disease. Whether this principle also applies to intracranial artery calcifications (I

B Bernhard P Berghout

The Effect of Telehomecare on Patients' Health-Related Quality of Life, Satisfaction, Disease Self-Management Skills, Provider Satisfaction, and Informal Caregiver Strain: Longitudinal Cohort and Cross-Sectional Study

JMIR Form Res. 2026 Jan 15;10:e70809. doi: 10.2196/70809.ABSTRACTBACKGROUND: Heart failure (HF) and chronic obstructive pulmonary disease (COPD) are responsible for a significant amount of the economic and chronic disease burden that impacts the Ontario health system. Telehomecare, a home self-manag

T Troy Francis

Evaluation of a Tailored Multifaceted Pharmaceutical Care Intervention to Optimize Chronic Obstructive Pulmonary Disease Management: Protocol for a Cluster Randomized Controlled Trial

JMIR Res Protoc. 2026 Jan 15;15:e82806. doi: 10.2196/82806.ABSTRACTBACKGROUND: Despite the widespread use of inhalation therapy, patients with chronic obstructive pulmonary disease (COPD) frequently experience suboptimal disease control due to medication nonadherence, improper inhaler use technique,

X Xuedi Ma

Early outcomes of facilitated transfemoral versus alternative access for transcatheter aortic valve replacement in patients with peripheral arterial disease

J Invasive Cardiol. 2026 Jan 8. doi: 10.25270/jic/25.00171. Online ahead of print.ABSTRACTOBJECTIVES: Transfemoral (TF) access for transcatheter aortic valve replacement (TAVR) may be challenging in patients with peripheral arterial disease (PAD). Alternative access through intra- and extrathoracic

A Ahmad Mustafa

Extended Endocrine Therapy Following 5 Years of Adjuvant Luteinizing Hormone-Releasing Hormone Agonist in Premenopausal Patients With Node-Positive, Hormone Receptor-Positive Breast Cancer: A Cohort Study

J Clin Oncol. 2026 Jan 15:JCO2501660. doi: 10.1200/JCO-25-01660. Online ahead of print.ABSTRACTPURPOSE: To evaluate the clinical benefit of extended endocrine therapy (eET) after 5 years of adjuvant treatment with luteinizing hormone-releasing hormone agonists (LHRHa) in premenopausal women with nod

C Carmine Valenza

PU.1-Activated Genomic Regions Define Low-risk MDS Subsets Characterized by Immune Dysregulation and Disease Progression

Blood. 2026 Jan 15:blood.2025030760. doi: 10.1182/blood.2025030760. Online ahead of print.ABSTRACTMyelodysplastic syndromes (MDS) are heterogeneous myeloid neoplasms with an increased risk of progression to secondary acute myeloid leukemia (sAML). This study investigates the genomic correlates of di

V Veronica Vallelonga

NUTRITIONAL ASSESSMENT AND ITS IMPACT ON QUALITY OF LIFE IN PATIENTS WITH INFLAMMATORY BOWEL DISEASE IN COLOMBIA: NUTRIBD - COL

Arq Gastroenterol. 2026 Jan 9;62:e25090. doi: 10.1590/S0004-2803.24612025-090. eCollection 2026.ABSTRACTBACKGROUND: Inflammatory bowel disease (IBD) significantly affects patients' nutritional status and quality of life (QoL). Nutritional deficiencies are frequent and may worsen disease outcomes. Th

V Viviana Parra-Izquierdo

Identification of anoikis-related biomarkers linking immune infiltration to acute myocardial infarction

Braz J Med Biol Res. 2026 Jan 9;58:e14989. doi: 10.1590/1414-431X2025e14989. eCollection 2026.ABSTRACTThis study was designed to identify new biomarkers for early diagnosis of acute myocardial infarction (AMI). GSE66360 and GSE48060 datasets were downloaded from the Gene Expression Omnibus (GEO) dat

Y Yang Zhao

Protection against myocardial ischemia reperfusion injury by liquiritin: involvement of autophagy restoration targeting PIK3CA

Braz J Med Biol Res. 2026 Jan 9;58:e14964. doi: 10.1590/1414-431X2025e14964. eCollection 2026.ABSTRACTThe current therapy for myocardial infarction focuses on reestablishing blood flow in the coronary arteries to reduce the ischemic area, but the subsequent damage caused by reperfusion cannot be ign

H Huizi Mao

Comparison between Five Risk Scores in Patients with Acute Coronary Syndromes Undergoing Surgical Revascularization during the Index Hospitalization

Arq Bras Cardiol. 2025 Nov;122(11):e20250320. doi: 10.36660/abc.20250320.ABSTRACTBACKGROUND: Risk scores (RS) for patients with acute coronary syndromes (ACS) and coronary artery bypass grafting (CABG) have been tested previously, but little is known about their value in ACS patients undergoing CABG

J José C Nicolau

Takotsubo Syndrome, Complete Heart Block, and Cardiac Arrest: A Clinical Challenge

Arq Bras Cardiol. 2025 Nov;122(11):e20250245. doi: 10.36660/abc.20250245.ABSTRACTComplete atrioventricular block may be associated with Takotsubo syndrome, and the decision of device implantation in such patients is challenging. We present a case of a 76-year-old woman admitted after out-of-hospital

A Ana Abrantes

Association of Plasma Osmolality with Cardiovascular Disease Risk: Evidence from the National Health and Nutrition Examination Survey Database

Arq Bras Cardiol. 2025 Nov;122(11):e20250176. doi: 10.36660/abc.20250176.ABSTRACTBACKGROUND: Cardiovascular disease (CVD) remains the world's leading cause of death. Because of its substantial public health burden, further research is needed to define risk factors that are both modifiable and measur

F Feng Gao

Photobiomodulation Combined with Moderate or High-Intensity Interval Training on Oxygen Consumption and Exercise Tolerance in Patients with Heart Failure

Arq Bras Cardiol. 2025 Nov;122(11):e20250086. doi: 10.36660/abc.20250086.ABSTRACTBACKGROUND: Aerobic training (AT), whether moderate or high intensity, is widely employed in cardiovascular rehabilitation. Photobiomodulation therapy (PBMT) has shown potential to enhance exercise performance in athlet

D Diego Busin

Cardiac CT-Detected Vulnerable Plaques and Risk of Future Acute Myocardial Infarction: Predictive Value of CAC Scores and Inflammatory Burden Index

Arq Bras Cardiol. 2025 Nov;122(11):e20250052. doi: 10.36660/abc.20250052.ABSTRACTBACKGROUND: Computed Tomography (CT) angiography is widely used as a basic non-invasive modality to evaluate coronary artery disease. Inflammatory burden index (IBI) is a systemic inflammation indicator reflecting the i

S Sefa Erdi Ömür

Evaluation of aortic stiffness with an oscillometric arteriograph device in patients with hypertension and ascending aortic aneurysm

Rev Assoc Med Bras (1992). 2026 Jan 9;71(12):e20250481. doi: 10.1590/1806-9282.20250481. eCollection 2026.ABSTRACTOBJECTIVE: The aim of this study was to compare central blood pressure, central pulse pressure, and parameters like augmentation index and pulse wave velocity, which are used to evaluate

A Abdulkadir Arpa

Proposing the ValvUS approach: integrating bedside tests and ultrasonography for severe valvular heart disease diagnosis

Einstein (Sao Paulo). 2026 Jan 12;24:eRW1487. doi: 10.31744/einstein_journal/2026RW1487. eCollection 2026.ABSTRACTValvular heart disease is increasingly prevalent, and bedside confirmation or exclusion of severe disease is needed to enable a rapid and cost-effective diagnostic workup. The physical e

T Tarso Augusto Duenhas Accorsi

Association of the rs2814778 variant in the ACKR1 gene, responsible for the Duffy erythrocyte antigen "null" phenotype, with COVID-19 severity in Southern Brazil

Einstein (Sao Paulo). 2026 Jan 12;24:eAO1543. doi: 10.31744/einstein_journal/2026AO1543. eCollection 2026.ABSTRACTOBJECTIVE: This study aimed to analyze the possible association between rs2814778, rs12075 ( ACKR1 gene), and rs4073 ( CXCL8 gene) single nucleotide variants and COVID-19 severity.METHOD

K Kelly Silvério Góis