Percutaneous Coronary Intervention and vascular access complications: A contemporary review

NPJ Cardiovasc Health. 2026 Apr 28;3(1):23. doi: 10.1038/s44325-026-00125-6.ABSTRACTTransradial approach (TRA) is preferred over transfemoral approach (TFA) for percutaneous coronary interventions due to lower bleeding, vascular complications, and mortality, particularly in acute coronary syndrome.

T Tanawat Attachaipanich

Longitudinal associations of cardiovascular-kidney-metabolic syndrome with midlife or late-life mental disorders and dementia, and the mediating role of metabolomic signature

Commun Med (Lond). 2026 Apr 28. doi: 10.1038/s43856-026-01608-4. Online ahead of print.ABSTRACTBACKGROUND: Cardiovascular-Kidney-Metabolic (CKM) syndrome assesses the interconnections among metabolic, kidney, and cardiovascular diseases, rendering significant prognostic value for age-related chronic

X Xuhao Zhao

Long-term treatment with denosumab in patients with celiac disease and osteoporosis at high risk of fracture: a retrospective study

Intern Emerg Med. 2026 Apr 28. doi: 10.1007/s11739-026-04360-8. Online ahead of print.ABSTRACTPatients with celiac disease have lower bone mineral density (BMD) and higher incidence of fractures compared to age- and sex-matched controls. There are no studies of denosumab, an antiresorptive drug, whi

J Jessica Pepe

Prognostic impact of serum type IV collagen 7S after transcatheter aortic valve implantation

Heart Vessels. 2026 Apr 29. doi: 10.1007/s00380-026-02705-z. Online ahead of print.ABSTRACTOutcomes after transcatheter aortic valve implantation (TAVI) remain variable, and the impact of extracardiac dysfunction prior to the procedure has not been fully elucidated. Type IV collagen 7S (P4NP 7S) is

K Kazuya Sakamoto

Impact of hyperuricemia on cardiac events in stable coronary artery disease patients with or without renal dysfunction

Heart Vessels. 2026 Apr 29. doi: 10.1007/s00380-026-02685-0. Online ahead of print.ABSTRACTPatients with hyperuricemia may have an elevated risk of cardiovascular events. Owing to the relationship between uric acid (UA) levels and renal function, the impact of hyperuricemia may differ depending on t

H Hiroki Kondo

Diagnostic accuracy of radiolabelled-WBC scintigraphy in patients with antibiotic therapy

No abstractEur J Nucl Med Mol Imaging. 2026 Apr 29. doi: 10.1007/s00259-026-07855-w. Online ahead of print.NO ABSTRACTPMID:42050256 | DOI:10.1007/s00259-026-07855-w

C Chiara Lauri

Integrated metabolomic profiling reveals metabolomic responses by epicardial and myocardial stromal cells to ischemia

Metabolomics. 2026 Apr 29;22(3):61. doi: 10.1007/s11306-026-02438-0.ABSTRACTINTRODUCTION: Cardiac ischemia induces substantial metabolomic reprogramming, which dysregulates cardiomyocytes (CMs) and non-myocyte stromal cell populations. The stromal cells derived from epicardial adipose tissue (EAT) a

D Dongwei Sun

Glucocorticoids combined with anticoagulation modulate the central NLRP3/NETosis inflammatory process in patients with severe cerebral venous thrombosis: a human mechanistic exploratory study

Inflamm Res. 2026 Apr 28;75(1):104. doi: 10.1007/s00011-026-02260-3.ABSTRACTOBJECTIVES: Neutrophil-mediated neuroinflammation plays a crucial role in secondary brain injury following severe cerebral venous thrombosis (CVT). Although previous studies have reported that the combination of glucocortico

Y Yu Li

The role of neutrophils in the pathogenesis of abdominal aortic aneurysms

Inflamm Res. 2026 Apr 28;75(1):107. doi: 10.1007/s00011-026-02258-x.ABSTRACTBACKGROUND: Abdominal aortic aneurysm (AAA) is a progressive degenerative vascular disease characterized by structural weakening and pathological dilatation of the abdominal aortic wall. Currently, no effective pharmacologic

S Stephen A Addo

Inhibition of the Microglial cGAS-STING Pathway Improves Neurological Deficits and Long-Term Hydrocephalus Symptoms in Mice with Intraventricular Hemorrhage

Mol Neurobiol. 2026 Apr 29;63(1):594. doi: 10.1007/s12035-026-05888-8.ABSTRACTPost-hemorrhagic hydrocephalus (PHH) represents a prevalent clinical form of hydrocephalus, where surgical interventions frequently fail or result in severe complications. While current research underscores the role of inn

H Hao-Xiang Wang

Metabolic markers of kidney function and oxidative stress are associated with heart failure with preserved ejection fraction (HFpEF) in individuals with metabolic dysfunction-associated steatotic liver disease (MASLD)

Metabolomics. 2026 Apr 29;22(3):62. doi: 10.1007/s11306-026-02441-5.ABSTRACTBACKGROUND AND AIM: Metabolic dysfunction-associated steatotic liver disease (MASLD) is associated with heart failure with preserved ejection fraction (HFpEF), independent of shared risk factors. The aim of this study was to

K Kara Wegermann

Evolving mortality trends in hypertension-associated ischemic heart disease among U.S. adults over two decades: a CDC wonder analysis (2000-2023)

J Hum Hypertens. 2026 Apr 29. doi: 10.1038/s41371-026-01154-5. Online ahead of print.ABSTRACTThis study aimed to evaluate national, demographic, and geographic trends in mortality associated with hypertension and ischemic heart disease (IHD) among U.S. adults from 1999 to 2023. Mortality data were e

M Muhammad Hamza Dawood

Comprehensive and visualized analysis of the global application of the international standards for neurological classification of spinal cord injury: A Bibliometric Study

Spinal Cord. 2026 Apr 28. doi: 10.1038/s41393-026-01209-x. Online ahead of print.ABSTRACTSTUDY DESIGN: Bibliometric analysis.OBJECTIVE: To analyze the global application of the International Standards for Neurological Classification of Spinal Cord Injury (ISNCSCI) and identify status and emerging tr

Y Yuquan Liu

Neutrophils exhibit distinct migration phenotypes that are modulated by transendothelial migration

Commun Biol. 2026 Apr 28. doi: 10.1038/s42003-026-10122-1. Online ahead of print.ABSTRACTThe extravasation of polymorphonuclear neutrophils (PMNs) is a critical component of the innate immune response that involves transendothelial migration (TEM) and interstitial migration. TEM-mediated interaction

A Amy B Schwartz

Neighborhood socioeconomic deprivation and physical activity associate with extracellular vesicle size and cargo in a community-based cohort of women

Sci Rep. 2026 Apr 28. doi: 10.1038/s41598-026-49679-6. Online ahead of print.ABSTRACTAfrican American (AA) women face disproportionate cardiovascular disease (CVD) risk due to adverse social determinants of health (SDoH), including lower socioeconomic status (SES). Physical activity (PA) and plasma

Y Yvonne Baumer

Inhaled corticosteroid overuse and deprescribing eligibility in COPD (iCODEC Study): a nationwide cross-sectional analysis in China

NPJ Prim Care Respir Med. 2026 Apr 28. doi: 10.1038/s41533-026-00519-0. Online ahead of print.ABSTRACTInhaled corticosteroid (ICS) overuse is common in chronic obstructive pulmonary disease (COPD) and associated with substantial adverse effects. Deprescribing has emerged as a strategy to optimize th

C Changcheng Shi

Alternatives to the Vegetable Oil Hydrogenation Process to Reduce Trans-Fatty Acids

Annu Rev Food Sci Technol. 2026 Apr;17(1):475-503. doi: 10.1146/annurev-food-052924-044712.ABSTRACTPartial hydrogenation (PH) is a traditional modification technique used to tailor the physicochemical properties of vegetable oils for applications in bakery products, margarines, shortenings, and conf

I Ityotagher P Aondoakaa

Clinical outcomes of ABO-incompatible kidney transplantation in recipients with extremely high baseline isoagglutinin titers: a two-center experience

Clin Transplant Res. 2026 Apr 29. doi: 10.4285/ctr.25.0104. Online ahead of print.ABSTRACTBACKGROUND: ABO-incompatible kidney transplantation (ABOi KT) has become increasingly feasible; however, recipients with very high baseline isoagglutinin titers continue to pose substantial clinical challenges.

J Jee Sung Kim

Negative Pressure Wound Therapy as a Key Strategy in the Management of Severe Diabetic Foot Ulcers in Septic Frail Patients: A Case Series

Int Wound J. 2026 May;23(5):e70926. doi: 10.1111/iwj.70926.ABSTRACTDiabetes mellitus represents a major global health challenge, with over 537 million adults currently affected worldwide. Among its complications, diabetic foot ulcers remain a leading cause of morbidity, hospitalization and amputatio

M Maria Ignacy Pirski

Assessment and management of cardiovascular-kidney-liver metabolic-syndrome in the primary care setting: A multidisciplinary consensus statement

Eur J Intern Med. 2026 Apr 27:106902. doi: 10.1016/j.ejim.2026.106902. Online ahead of print.ABSTRACTThe recently introduced cardiovascular-kidney-metabolic (CKM) syndrome captures the close interplay between metabolic risk factors, chronic kidney disease, and cardiovascular disease, but insufficien

R Reinhold Kreutz

Correspondence on: Impact of coronary artery disease patterns assessed with pullback pressure gradient on clinical outcomes: Meta-analysis

No abstractAtherosclerosis. 2026 Apr 25:120752. doi: 10.1016/j.atherosclerosis.2026.120752. Online ahead of print.NO ABSTRACTPMID:42049577 | DOI:10.1016/j.atherosclerosis.2026.120752

A Artur Dziewierz

Emerging and Off-Label Uses Of Glucagon-Like Peptide-1 Receptor Agonists (GLP1-RA) and Dual GIP/GLP1-RAs

J Am Board Fam Med. 2026 Jan;39(1):157891. doi: 10.3122/jabfm.2025.250158R1.ABSTRACTBACKGROUND: Glucagon-like peptide-1 receptor agonists (GLP1-RAs) and the glucagon-dependent insulinotropic polypeptide (GIP)/GLP1-RA are approved for type 2 diabetes (T2D) and obesity given their profound impact on g

C Candis M Morello

Association of TIMP2 Gene Variants With Development of Diabetic Retinopathy

In Vivo. 2026 May-Jun;40(3):1348-1356. doi: 10.21873/invivo.14287.ABSTRACTBACKGROUND/AIM: Diabetic retinopathy (DR) is a common comorbidity of diabetes involving the formation of abnormal vascular structures in the retina. Tissue inhibitor of metalloproteinases 2 (TIMP2), initially identified as a k

C Chin-Te Huang

Microarray Analysis of Human Abdominal Aortic Aneurysm With Emphasis on Cardiovascular Genes Revealed Differentially Expressed Genes

In Vivo. 2026 May-Jun;40(3):1327-1347. doi: 10.21873/invivo.14286.ABSTRACTBACKGROUND/AIM: We examined gene expression profiles in abdominal aortic aneurysm (AAA) lesions vs. normal aortas by cDNA microarray and real-time quantitative reverse-transcriptase polymerase chain reaction (qRT-PCR).MATERIAL

S Song Lu