Generation of three induced pluripotent stem cell lines from an immune checkpoint inhibitor-induced myocarditis patient and controls

Stem Cell Res. 2026 Jul 6;95:104057. doi: 10.1016/j.scr.2026.104057. Online ahead of print.ABSTRACTImmune checkpoint inhibitor-associated myocarditis (ICIM) is an uncommon but potentially fatal inflammatory heart disease triggered by cancer immunotherapy, with up to 40% mortality. The underlying mec

Y Yin Sun

Symptom-Only Localization of Brainstem Ischemia Using Large Language Models Versus Neurologists in Diffusion-Weighted Imaging-Positive Cases: Retrospective Single-Center Study

JMIR Form Res. 2026 Jul 8;10:e87163. doi: 10.2196/87163.ABSTRACTBACKGROUND: Symptom-based localization of brainstem ischemia is challenging because of the anatomical complexity of the brainstem and the nonspecific overlap of clinical syndromes. Whether large language models (LLMs) can meaningfully a

N Nedim Beste

A functional framework in patient fibroblasts informs ATP7A variant pathogenicity and identifies p.Q990P as a novel cause of distal motor neuropathy

Hum Mol Genet. 2026 Jun 6;35(14):ddag061. doi: 10.1093/hmg/ddag061.ABSTRACTATP7A is a P-type ATPase copper transporter and a central component of the intracellular network to maintain copper (Cu) homeostasis, trafficking between the trans-Golgi network (TGN) and the cell periphery in response to int

G Gonzalo Perez-Siles

The Characteristics of Vagal Response During Radiofrequency Pulmonary Vein Isolation in Paroxysmal Atrial Fibrillation With Heart Failure

J Cardiovasc Electrophysiol. 2026 Jul 8. doi: 10.1111/jce.70428. Online ahead of print.ABSTRACTBACKGROUND: Vagal response (VR) was thought to the successful rate in catheter ablation of atrial fibrillation (AF). However, little is known about VR during pulmonary vein isolation (PVI) in AF and heart

E Erpeng Liang

Intracardiac Echocardiography for Procedural Guidance of Left Atrial Appendage Occlusion From Right Atrium: A Subgroup From a Multicenter Randomized Controlled Trial With Two Intracardiac Echocardiography Imaging Systems

J Cardiovasc Electrophysiol. 2026 Jul 8. doi: 10.1111/jce.70450. Online ahead of print.ABSTRACTBACKGROUND: Intracardiac echocardiography (ICE)-guided left atrial appendage occlusion (LAAO) from left atrium under local anesthesia showed potential advantages over transesophageal echocardiography (TOE)

B Bijun Huang

Molecular Mechanisms and Current Research Status of Salvianolic Acid B in the Treatment of Cardiovascular Diseases

J Agric Food Chem. 2026 Jul 8. doi: 10.1021/acs.jafc.5c15233. Online ahead of print.ABSTRACTSalvianolic acid B (Sal B), a polyphenolic constituent of Danshen. It has demonstrated therapeutic potential in cardiovascular diseases by targeting a spectrum of pathological processes. This review comprehen

Y Yaolong Han

Using the RE-AIM framework to evaluate the implementation of a clinical workflow designed to identify, refer, and connect insufficiently active patients to health coaching

Transl Behav Med. 2026 Jan 7;16(1):ibag036. doi: 10.1093/tbm/ibag036.ABSTRACTBACKGROUND: Primary care is well-positioned to connect patients to physical activity (PA) interventions but is underutilized.PURPOSE: To describe the implementation of a clinical workflow designed to identify, refer, and co

G Garrett M Steinbrink

Clinicopathologic characterization of plasma cell neoplasms with IGH::CCND3

Am J Clin Pathol. 2026 Jul 6;166(1):aqag080. doi: 10.1093/ajcp/aqag080.ABSTRACTOBJECTIVES: Plasma cell neoplasms (PCNs) harboring IGH::CCND3 (t(6;14)) are rare (<1% of PCNs). We sought to study these cases, as they have not been studied as a distinct entity, and their clinicopathologic features are

N Nandan Padmanabha

Frugal Innovations for Delivering Child Cardiac Care in India

NEJM Catal Innov Care Deliv. 2026 Jul;7(7):CAT250219. doi: 10.1056/CAT.25.0219. Epub 2026 Jun 17.ABSTRACTCongenital heart defects (CHDs) affect approximately 240,000 newborns annually in India, where lifesaving surgical interventions are inaccessible and unaffordable for rural populations. The objec

W Wasan Kumar

Delivering Lifestyle Interventions for Chronic Disease Care Sustainably and at Scale through Virtual Shared Medical Appointments in Primary Care

NEJM Catal Innov Care Deliv. 2026 Jun;7(6):CAT250284. doi: 10.1056/CAT.25.0284. Epub 2026 May 20.ABSTRACTBehavior changes related to nutrition, physical activity, sleep, alcohol, and smoking are critical for the prevention and management of many chronic diseases, but interventions to implement these

J Jacob Mirsky

VCAM-1-targeting peptide assemblies protect vascular endothelium and prolong cardiac xenograft survival

Sci Adv. 2026 Jul 10;12(28):eaec5707. doi: 10.1126/sciadv.aec5707. Epub 2026 Jul 8.ABSTRACTCardiac xenotransplantation represents a promising strategy to address the shortage of donor hearts, yet endothelial cell dysfunction remains a major obstacle to long-term graft survival. Using integrated sing

Y Yi-Jing Li

Cardiovascular Health Equity: Time for a New Era of Science, Sociology, and Interventions

No abstractCirculation. 2026 Jul 8. doi: 10.1161/CIR.0000000000001445. Online ahead of print.NO ABSTRACTPMID:42418562 | DOI:10.1161/CIR.0000000000001445

D Dipti Itchhaporia

The CHECK-IT Program - Controlling Hypertension in Black Communities through In-Person and Virtual Interventions

NEJM Catal Innov Care Deliv. 2026 Apr;7(4):CAT250130. doi: 10.1056/CAT.25.0130. Epub 2026 Mar 11.ABSTRACTIn the United States, Black adults experience disproportionately high rates of hypertension and are nearly twice as likely to die due to a cardiovascular disease-related complication as white adu

E Erika Cheng

Impact of the albumin-bilirubin score on short- and long-term mortality in native and prosthetic valve endocarditis ALBI score and mortality in native and prosthetic valve endocarditis

Acta Cardiol. 2026 Jul 8:1-11. doi: 10.1080/00015385.2026.2695357. Online ahead of print.ABSTRACTBACKGROUND: Infective endocarditis (IE), involving both native and prosthetic valves, remains a severe multisystem disease associated with high early and long-term mortality despite advances in antimicro

K Kadir Bıyıklı

Knowledge Level of Cardiovascular Disease Risk Factors and Sleep Quality in People With Epilepsy

Brain Behav. 2026 Jul;16(7):e71573. doi: 10.1002/brb3.71573.ABSTRACTBACKGROUND: Knowledge level about sleep quality and cardiovascular disease risk factors in people with epilepsy is an important but insufficiently researched area.OBJECTIVE: This study was conducted to determine the knowledge level

H Heycan Erdoğan

Identification of the MYH6 c.804G>C Synonymous Variant Causing Exon Skipping in a Hypertrophic Cardiomyopathy Family

Mol Genet Genomic Med. 2026 Jul;14(7):e70268. doi: 10.1002/mgg3.70268.ABSTRACTBACKGROUND: Hypertrophic cardiomyopathy (HCM) is a common hereditary cardiac disorder characterized by left ventricular hypertrophy, outflow tract obstruction, arrhythmias, and increased risk of sudden cardiac death.METHOD

S Songlin Zhang

Circadian screening of neutrophils identifies therapeutic targets in multiple sclerosis

Proc Natl Acad Sci U S A. 2026 Jul 14;123(28):e2536812123. doi: 10.1073/pnas.2536812123. Epub 2026 Jul 8.ABSTRACTCircadian rhythms are intrinsic time-keeping mechanisms that play a critical role in tuning immunity. Here, we investigated the impact of circadian rhythms on the pathogenesis of experime

F Francesco De Virgiliis

Machine-Learning-Assisted Catalytic Sensor Array for Rapid Diagnosis of Aortic Dissection

Anal Chem. 2026 Jul 8. doi: 10.1021/acs.analchem.6c03030. Online ahead of print.ABSTRACTAcute aortic dissection (AD) is a time-critical cardiovascular emergency that is clinically difficult to distinguish from other causes of acute chest pain. Rapid blood diagnostics with high specificity for AD are

S Siyun Guo

Time-resolved proteolipidomics of the human aorta identifies stage-specific lipid-protein modules across development and aging

Cell Rep. 2026 Jul 8;45(7):117666. doi: 10.1016/j.celrep.2026.117666. Online ahead of print.ABSTRACTAn established vascular network is a prerequisite to ensuring an optimal supply of oxygen and nutrients for sustaining developmental events and systemic function. Herein, we construct a time-resolved

H Hao Cui

ACA-A1 segment development affects basal ganglia infarct severity and thrombectomy safety in MCA occlusion

Eur Stroke J. 2026 Jul 6;11(7):aakag054. doi: 10.1093/esj/aakag054.ABSTRACTINTRODUCTION: The lenticulostriate arteries (LSAs) demonstrate developmental variability that is linked to the A1 segment of the anterior cerebral artery (ACA) anatomy. In acute ischaemic stroke (AIS) with MCA occlusion, basa

W Wenping Sun

Contemporary achievement of guideline recommendations for blood pressure management after stroke in the CONVINCE trial

Eur Stroke J. 2026 Jul 6;11(7):aakag051. doi: 10.1093/esj/aakag051.ABSTRACTINTRODUCTION: Hypertension is a major modifiable risk factor for stroke. Studies between 1996 and 2013 reported high rates of non-achievement of guideline recommended blood pressure (BP) targets following stroke/TIA. Few rece

P Pádraig Synnott

Current outcomes of interventions to treat mixed arterial-venous ulcers

Phlebology. 2026 Jul 8:2683555261465585. doi: 10.1177/02683555261465585. Online ahead of print.ABSTRACTObjectiveTo analyze outcomes of initial combined arterial and venous interventions (AVI) compared with isolated venous interventions (VI) alone in patients with mixed arterial-venous ulcer (MAVLU).

J Joseph P Hart

Transforming Preeclampsia Care: Molecular Diagnostics and Therapeutic Innovations

J Am Soc Nephrol. 2026 Jul 8. doi: 10.1681/ASN.0000001197. Online ahead of print.ABSTRACTPreeclampsia is a leading cause of maternal and perinatal morbidity and mortality worldwide. Recent discoveries identifying circulating anti-angiogenic factors-particularly soluble fms-like tyrosine kinase-1 (sF

R Ravi Thadhani

TRIM38 Alleviates Ferroptosis in Heart Failure by Inactivating the TRAF6-p38 MAPK Pathway via Ubiquitinating Degradation of IRAK1

Drug Dev Res. 2026 Aug;87(5):e70340. doi: 10.1002/ddr.70340.ABSTRACTThis article explored the role of TRIM38 in ferroptosis in heart failure (HF) and its underlying mechanisms. Methodologically, serum TRIM38, IRAK1 and TRAF6 proteins from HF patients were detected by Western blot. In an in vitro stu

Y Yun Liu