Debating targets for systolic blood pressure lowering in CKD

Nephrol Dial Transplant. 2026 Oct 12:gfag233. doi: 10.1093/ndt/gfag233. Online ahead of print.ABSTRACTFor several decades, there was no clinical-trial evidence to demonstrate that intensive blood pressure (BP)-lowering is a therapeutic strategy that prolongs survival and reduces the cardiorenal risk

E Evangelia Dounousi

Longitudinal Sleep Patterns and Risk of Type 2 Diabetes Mellitus

Diabetes Metab Res Rev. 2026 Oct;42(7):e70237. doi: 10.1002/dmrr.70237.ABSTRACTAIMS: Evidence relating sleep characteristics to type 2 diabetes mellitus (T2DM) has largely been based on single assessments. We examined whether transitions in a multidimensional healthy sleep score between two assessme

Y Ying Zhang

Blood pressure and homocysteine-lowering effects of the amlodipine/folic acid combination in patients with hypertension and serum homocysteine concentration ≥10 μmol/l (H-type hypertension): a multicenter, randomized, double-blind, parallel-controlled clinical trial

J Hypertens. 2026 Aug 31. doi: 10.1097/HJH.0000000000004420. Online ahead of print.ABSTRACTBACKGROUND: Elevated plasma homocysteine (Hcy ≥10 μmol/l) and hypertension, defined as H-type hypertension, can synergistically increase the risk of cardiovascular diseases, especially for stroke. We aimed to

J Jianping Li

Blood pressure targets in adults with hypertension

Cochrane Database Syst Rev. 2026 Oct 12;10:CD016397. doi: 10.1002/14651858.CD016397.ABSTRACTThis is a protocol for a Cochrane review (intervention). The objectives are as follows: Primary objective To evaluate the benefits and harms of lower targets of blood pressure (BP; i.e. BP ≤ 135/85 mmHg) vers

D Doreen Y Larvie

Parinaud syndrome : a diplopia unlike any other

Rev Med Liege. 2026 Oct;81(10):569-573.ABSTRACTSudden-onset diplopia warrants an emergency management in ophthalmology. A binocular, vertical and persistent diplopia, should raise suspicion of a central lesion, particularly within the brainstem. We reporte the case of a 53-year-old man, who presente

L Lydia Belhabib