Sci Rep. 2026 Aug 4;16(1):24020. doi: 10.1038/s41598-026-64038-1.ABSTRACTFor most people living with Human immunodeficiency virus (HIV), virus control and sufficient immune function can be achieved with polypharmacotherapy. A minority is intolerant to thereto, and drug-resistant mutants are emerging
Cell Death Dis. 2026 Jun 5;17(1):682. doi: 10.1038/s41419-026-08951-3.ABSTRACTTubular epithelial cell (TEC)-macrophage crosstalk contributes to aldosterone (Aldo)-dependent renal fibrosis in hypertension. Extracellular ATP (eATP) can act as a mediator of TEC-macrophage crosstalk. However, whether an
Am J Physiol Heart Circ Physiol. 2026 Aug 4. doi: 10.1152/ajpheart.00517.2026. Online ahead of print.ABSTRACTPatients with chronic inflammatory disorders, including inflammatory bowel disease (IBD), carry an increased risk of cardiovascular disease. The 2022 ORAL Surveillance study reported that the
Neurosurg Rev. 2026 Aug 5;49(1):512. doi: 10.1007/s10143-026-04426-3.ABSTRACTMinimally invasive surgery (MIS) for spontaneous supratentorial intracerebral hemorrhage (sICH) includes endoscopic evacuation and catheter-based evacuation (aspiration or drainage ± thrombolysis), but comparative performan
Diabetes Obes Metab. 2026 Aug 4. doi: 10.1111/dom.71010. Online ahead of print.ABSTRACTAIMS: An update to the NICE Type 2 diabetes (T2DM) guideline in February 2022 recommended an SGLT2 inhibitor be offered to people with cardiovascular disease (CVD) or heart failure (HF) as comorbidities and consid
J Diabetes. 2026 Aug;18(8):e70260. doi: 10.1111/1753-0407.70260.ABSTRACTBACKGROUND: The combined prognostic value of continuous glucose monitoring (CGM) metrics and circulating glucose biomarkers for predicting mortality in type 2 diabetes has not been fully established, particularly regarding resid
J Clin Lipidol. 2026 Jul 14:S1933-2874(26)00446-0. doi: 10.1016/j.jacl.2026.07.018. Online ahead of print.ABSTRACTBACKGROUND: Elevated remnant cholesterol (RC) is implicated in the pathogenesis of atherosclerosis.OBJECTIVE: To assess the prognostic role of RC in atherosclerotic cardiovascular diseas
Cardiovasc Revasc Med. 2026 Jul 30:S1553-8389(26)00324-6. doi: 10.1016/j.carrev.2026.07.016. Online ahead of print.ABSTRACTBACKGROUND: Pulmonary artery catheterization (PAC) has re-emerged as a hemodynamic phenotyping tool in heart failure-related cardiogenic shock (HF-CS). Contemporary national dat
Heart. 2026 Aug 4:heartjnl-2025-326751. doi: 10.1136/heartjnl-2025-326751. Online ahead of print.ABSTRACTDespite recent advances in prevention and treatment, cardiovascular disease (CVD) remains a leading cause of premature death and disability globally, with a rising burden in many low- and middle-
J Cardiovasc Pharmacol. 2026 Aug 4. doi: 10.1097/FJC.0000000000001867. Online ahead of print.ABSTRACTBACKGROUND: Corticosteroids are widely used in pericarditis despite guideline recommendations reserving them for select indications. Observational studies have reported inconsistent associations betw
RMD Open. 2026 Aug 4;12(3):e006860. doi: 10.1136/rmdopen-2026-006860.ABSTRACTOBJECTIVE: This systematic literature review (SLR) aims to update the evidence regarding therapeutic strategies in difficult-to-treat rheumatoid arthritis (D2T RA), building on the previous SLR informing the European Allian
Best Pract Res Clin Anaesthesiol. 2026 Mar;40(1):41-54. doi: 10.1016/j.bpa.2026.06.004. Epub 2026 Jun 12.ABSTRACTStress-induced cardiomyopathy (siCM), also known as Takotsubo syndrome, is an acute, transient, and typically reversible form of myocardial dysfunction. In the intensive care unit (ICU),
BMJ Open. 2026 Aug 4;16(8):e107667. doi: 10.1136/bmjopen-2025-107667.ABSTRACTOBJECTIVES: To assess levels of and trends in knowledge that smoking and secondhand smoke (SHS) cause lung cancer and cardiovascular disease (CVD) in 46 countries over two decades.DESIGN: Longitudinal cohort and repeat cros
Clin Appl Thromb Hemost. 2026 Jan-Dec;32:10760296261476825. doi: 10.1177/10760296261476825. Epub 2026 Aug 4.ABSTRACTBackgroundVenous thromboembolism (VTE) is a leading cause of maternal morbidity and mortality, during postpartum period. It may be mitigated through pharmacological and non-pharmacolog
Lab Med. 2026 Aug 4;57(5):lmag044. doi: 10.1093/labmed/lmag044.ABSTRACTINTRODUCTION: This study retrospectively characterized the laboratory features of direct antiglobulin test (DAT)-positive anemia in newly diagnosed multiple myeloma (MM) and explored associated immunologic alterations to better u
Am J Cardiol. 2026 Aug 4:S0002-9149(26)00476-5. doi: 10.1016/j.amjcard.2026.07.022. Online ahead of print.ABSTRACTBACKGROUND: Pulmonary hypertension associated with left heart disease (PH-LHD) is the most prevalent form of pulmonary hypertension. Despite the recent advances in medications for pulmon
Am J Med. 2026 Aug 4:S0002-9343(26)00510-3. doi: 10.1016/j.amjmed.2026.06.034. Online ahead of print.ABSTRACTBACKGROUND: Proprotein convertase subtilisin/kexin type 9 (PCSK9) targeted therapies have been shown to reduce low-density lipoprotein cholesterol (LDL-C) levels and circulating PCSK9. Howeve
Respir Med. 2026 Aug 4:109073. doi: 10.1016/j.rmed.2026.109073. Online ahead of print.ABSTRACTBACKGROUND: Interstitial lung disease (ILD) is a heterogeneous group of more than 200 diseases that cause fibrosis or inflammation of the pulmonary parenchyma. ILD is a leading cause of death, yet data on i
Diabetes Res Clin Pract. 2026 Aug 4:113484. doi: 10.1016/j.diabres.2026.113484. Online ahead of print.ABSTRACTAIMS: Few studies have examined menopause's impact on health outcomes in women living with Type 1 diabetes mellitus (T1D). We compared physical, diabetes-related, and psychosocial outcomes b
Metabolism. 2026 Aug 4:156724. doi: 10.1016/j.metabol.2026.156724. Online ahead of print.ABSTRACTBACKGROUND: Despite advances in managing traditional cardiovascular risk factors and promoting healthy lifestyles, recurrence of cardiovascular events remains high in patients with established coronary h
Metabolism. 2026 Aug 4:156727. doi: 10.1016/j.metabol.2026.156727. Online ahead of print.ABSTRACTBACKGROUND: Peripheral artery disease (PAD) risk varies substantially across glycemic states, but glycemic status-specific proteomic features of PAD remain poorly characterized. This study aimed to provi
J Vasc Surg Venous Lymphat Disord. 2026 Aug 4:102593. doi: 10.1016/j.jvsv.2026.102593. Online ahead of print.ABSTRACTChronic venous disease (CVD) and varicose veins (VV) are highly prevalent yet remain inconsistently managed despite existing guidelines, with variability in treatment selection, patie
J Affect Disord. 2026 Aug 4:122349. doi: 10.1016/j.jad.2026.122349. Online ahead of print.ABSTRACTOBJECTIVE: Depression poses major global health challenges and accelerates chronic disease development, yet remains undertreated due to reliance on subjective diagnostics. The retina, as an embryologica
J Int Med Res. 2026 Aug;54(8):3000605261473180. doi: 10.1177/03000605261473180. Epub 2026 Aug 4.ABSTRACTMacular telangiectasia type 2 is a genetically complex disorder with variable penetrance and expressivity. Although several causative genes have been identified, the genetic basis remains unknown
