ADAM17 and its proteolytic targets in disease pathogenesis

FEBS J. 2026 Mar 23. doi: 10.1111/febs.70516. Online ahead of print.ABSTRACTADAM17, from the disintegrin and metalloproteinase (ADAM) family, also called tumor necrosis factor converting enzyme (TACE), is a pleiotropic protease with more than 90 substrates, including growth factors, cytokines, recep

A Abdulbasit Amin

RNA-Based Therapies for Hypercholesterolemia and Coronary Artery Disease

Cureus. 2026 Feb 18;18(2):e103877. doi: 10.7759/cureus.103877. eCollection 2026 Feb.ABSTRACTRNA-based therapies have emerged as a transformative approach in the management of hypercholesterolemia and coronary artery disease by directly targeting molecular pathways involved in lipid regulation. These

M Maynor Jose Lopez Mendoza

MINOCA (Myocardial Infarction With Non-obstructive Coronary Arteries) Due to Diffuse Coronary Microvascular Dysfunction in a Patient With Systemic Autoimmune Disease and Chronic Kidney Disease

Cureus. 2026 Feb 18;18(2):e103816. doi: 10.7759/cureus.103816. eCollection 2026 Feb.ABSTRACTMyocardial infarction with non-obstructive coronary arteries (MINOCA) represents a heterogeneous entity requiring systematic exclusion of alternative diagnoses and identification of the underlying mechanism.

T Teenu Kamboj