Prasugrel: Reassessing Its Role in Contemporary Antiplatelet Therapy

Cardiovasc Ther. 2026;2026(1):e5538781. doi: 10.1155/cdr/5538781.ABSTRACTManaging acute coronary syndrome (ACS) and atherosclerotic cardiovascular disease remains clinically challenging, requiring a careful balance between ischemic protection and bleeding risk. Antiplatelet therapy is central to the

Y Yusof Kamisah

The uric acid-to-high-density lipoprotein cholesterol ratio, neutrophil-to-high-density lipoprotein cholesterol ratio, and lymphocyte-to-high-density lipoprotein cholesterol ratio as risk indicators for mortality in congestive heart failure: A cross-sectional analysis of NHANES 2003 to 2016

Medicine (Baltimore). 2026 Jun 26;105(26):e49313. doi: 10.1097/MD.0000000000049313.ABSTRACTWhile individual lipid and inflammatory markers have been linked to heart failure outcomes, the prognostic value of the uric acid-to-high-density lipoprotein (HDL) cholesterol ratio (UHR), neutrophil-to-HDL ch

X Xinxin Wang

Nonlinear association between systemic inflammation response index and mortality in adult cardiac surgery-associated acute kidney injury: A retrospective Cohort study based on the MIMIC-IV database

Medicine (Baltimore). 2026 Jun 26;105(26):e49168. doi: 10.1097/MD.0000000000049168.ABSTRACTSystemic inflammation plays a pivotal role in the pathogenesis and prognosis of cardiac surgery-associated acute kidney injury (CSA-AKI). The Systemic Inflammation Response Index (SIRI) has emerged as a novel

T Tong Tan

The Carbothalamus: Villain and Victim in Metabolic Care

J Pak Med Assoc. 2026 Jun;76(6):964-966. doi: 10.47391/JPMA.26-43.ABSTRACTThe hypothalamus, through its expression and interaction with various neurotransmitters, pituitary hormones and orexigenic and anorexigenic signals, regulates appetite. Leptin and insulin, released in response to food intake,

P Parag Agrawal

Associations of cumulative exposure and longitudinal change patterns of the triglyceride glucose-Chinese visceral adiposity index with incident cardiovascular disease in middle-aged and older adults: evidence from CHARLS

Cardiovasc Diabetol. 2026 Jun 26. doi: 10.1186/s12933-026-03258-1. Online ahead of print.ABSTRACTBACKGROUND: The triglyceride glucose-Chinese visceral adiposity index (TyG-CVAI), an integrated marker of insulin resistance and visceral adiposity, has been associated with cardiovascular outcomes. Howe

H Huilin Liu