Geriatr Nurs. 2026 Jan 23;68:103834. doi: 10.1016/j.gerinurse.2026.103834. Online ahead of print.ABSTRACTBACKGROUND: To investigate the associations of physical activity (PA) and sedentary behavior (SB) with the risk of mortality using observational and Mendelian randomization (MR) designs.METHODS:
Nutrition. 2025 Dec 22;145:113071. doi: 10.1016/j.nut.2025.113071. Online ahead of print.ABSTRACTBACKGROUND: Cancer remains a leading global health burden, yet survival rates are improving due to better prevention and treatment advances. In this systematic review and meta-analysis we investigate the
Maturitas. 2026 Jan 22;206:108837. doi: 10.1016/j.maturitas.2026.108837. Online ahead of print.ABSTRACTBACKGROUND: The formulations and usage patterns of oral contraceptives have evolved, necessitating updated evidence on their long-term safety.OBJECTIVE: To assess the associations between duration
Am J Case Rep. 2026 Jan 24;27:e949682. doi: 10.12659/AJCR.949682.ABSTRACTBACKGROUND Wellens syndrome is considered as equivalent to ST elevation myocardial infarction and is highly specific for critical stenosis of the proximal left anterior descending (LAD) coronary artery. Prolonged QT interval is
CONCLUSIONS: In summary, these findings demonstrate that H(2) confers neuroprotection in SCIRI through the activation of the Nrf2/HO-1 signaling pathway and the inhibition of ferroptosis.Mol Biol Rep. 2026 Jan 24;53(1):324. doi: 10.1007/s11033-026-11482-x.ABSTRACTPURPOSE: Spinal cord ischemia-reperf
J Interv Card Electrophysiol. 2026 Jan 24. doi: 10.1007/s10840-025-02227-0. Online ahead of print.ABSTRACTBACKGROUND: Conduction disease is common in patients with interventricular septal hypertrophy (IVSH). Left bundle branch area pacing (LBBAP) is a physiological pacing approach which preserves in
Neurosurg Rev. 2026 Jan 24;49(1):158. doi: 10.1007/s10143-025-04095-8.ABSTRACTHemorrhagic stroke (HS) is a severe condition with high mortality. Identifying high-risk patients for early intervention remains challenging. The triglyceride-glucose-body mass index (TyG-BMI), a simple and cost-effective
CEN Case Rep. 2026 Jan 24;15(1):35. doi: 10.1007/s13730-025-01075-1.ABSTRACTBehçet's disease (BD) is a non-infectious inflammatory condition characterized by neutrophilic infiltration. In addition to primary symptoms, including oral and genital ulcers, ocular involvement, and skin lesions, BD can al
Cardiovasc Drugs Ther. 2026 Jan 24. doi: 10.1007/s10557-026-07836-z. Online ahead of print.ABSTRACTBACKGROUND: Neutrophil extracellular traps (NETs) play a crucial role in the pathogenesis of acute myocardial infarction (AMI), but the role of high-mobility group box 1 (HMGB1), a key target of the ce
Cell Mol Neurobiol. 2026 Jan 24. doi: 10.1007/s10571-026-01668-z. Online ahead of print.ABSTRACTFerroptosis, a novel form of cell death primarily characterized by iron overload and lipid peroxidation, differs from traditional apoptosis and is finely regulated by multiple mechanisms. Recent studies h
Neurol Sci. 2026 Jan 24;47(2):191. doi: 10.1007/s10072-025-08625-6.ABSTRACTBACKGROUND: Data regarding management of patients already on an antiplatelet when presenting with an ischaemic stroke or transient ischaemic attack (TIA) are limited. This secondary analysis of the triple antiplatelets for re
Public Health Nurs. 2026 Jan 24. doi: 10.1111/phn.70072. Online ahead of print.ABSTRACTOBJECTIVE: This study explored barriers to cardiovascular rehabilitation (CR) participation among individuals with cardiovascular disease (CVD) and risk factors in a rural, low-resource setting.DESIGN: A qualitati
Clin Exp Hypertens. 2026 Dec 31;48(1):2617514. doi: 10.1080/10641963.2026.2617514. Epub 2026 Jan 24.ABSTRACTBACKGROUND: Malignant hypertension (mHTN) is a severe hypertensive emergency, often associated with renal deterioration. Kidney length may be of useful to identify patients with renal dysfunct
Age Ageing. 2026 Jan 3;55(1):afaf379. doi: 10.1093/ageing/afaf379.ABSTRACTBACKGROUND: Falls are a major health concern for older adults, affecting one-third of those over 65 years annually, with 10%-20% leading to injury or hospitalisation. Whilst falls are often multifactorial, unexplained falls ma
Eur Heart J. 2026 Jan 24;47(4):490-499. doi: 10.1093/eurheartj/ehaf975.ABSTRACTBACKGROUND AND AIMS: Elevated cardiac troponin levels are a frequent finding in emergency department patients, often without a clear cause. Current high-sensitivity cardiac troponin T (cTnT) assays measure intact and frag
Scand J Med Sci Sports. 2026 Feb;36(2):e70211. doi: 10.1111/sms.70211.ABSTRACTLow-load blood flow restriction training (LLBFRT) induces significant vascular stress, which is often associated with vascular remodeling, increased capillarization and muscle blood flow. These adaptations may be of intere
Appl Nurs Res. 2026 Feb;87:152043. doi: 10.1016/j.apnr.2025.152043. Epub 2025 Dec 22.ABSTRACTAIMS: Cognitive frailty, defined as the coexistence of frailty and cognitive impairment, poses a dual burden in elderly heart failure (HF) patients. Its impact on clinical outcomes, particularly hospitalizat
Appl Nurs Res. 2026 Feb;87:152039. doi: 10.1016/j.apnr.2025.152039. Epub 2025 Nov 30.ABSTRACTAIM: To test the bidirectional mediating relationships among heart failure (HF) symptoms, depressive symptoms, and health-related quality of life (HRQoL) in patients with HF, controlling for age, functional
Protein Sci. 2026 Feb;35(2):e70490. doi: 10.1002/pro.70490.ABSTRACTMyopalladin (MYPN) is a striated muscle-specific protein essential for sarcomere integrity and actin filament organization. The Ig3 domain of MYPN mediates direct binding and bundling of filamentous actin (F-actin), and several cardi
Rheumatology (Oxford). 2026 Jan 24:keag036. doi: 10.1093/rheumatology/keag036. Online ahead of print.ABSTRACTOBJECTIVE: Interferons (IFNs) are implicated in the pathogenesis of rheumatoid arthritis (RA). However, the relationship between serum levels of IFN-α and IFN-γ and the clinical manifestation
Nephrol Dial Transplant. 2026 Jan 24:gfag007. doi: 10.1093/ndt/gfag007. Online ahead of print.ABSTRACTKidney diseases are among the fastest-growing global health burdens, with chronic kidney disease (CKD) projected to become the third leading cause of death by 2050. Despite this, therapeutic innovat
Med Oral Patol Oral Cir Bucal. 2026 Jan 24:27981. doi: 10.4317/medoral.27981. Online ahead of print.ABSTRACTBACKGROUND: Periodontal disease (PD) is a prevalent chronic inflammatory condition linked to cardiovascular disease, diabetes mellitus and dementia, yet it is unclear how far medical specialty
CNS Neurosci Ther. 2026 Jan;32(1):e70740. doi: 10.1002/cns.70740.ABSTRACTAIMS: Intraventricular hemorrhage (IVH) has a high mortality and disability rate and poses significant clinical challenges, which often leads to hydrocephalus and neurological dysfunction. Emerging evidence implicates dysfuncti
Genet Med. 2026 Jan 20:102070. doi: 10.1016/j.gim.2026.102070. Online ahead of print.ABSTRACTKleefstra syndrome (KLEFS1) is a rare monogenic neurodevelopmental disorder (mNDD) with multisystem involvement, caused by disruption of EHMT1 function, resulting in significant burden on affected individual
