Association between perceived stress and metabolic parameters: a systematic review and meta-analysis

Diabetol Metab Syndr. 2026 Jun 27. doi: 10.1186/s13098-026-02220-1. Online ahead of print.ABSTRACTBACKGROUND: Metabolic syndrome (MetS) is a major global public health problem associated with cardiovascular disease, type 2 diabetes mellitus (T2D), and increased mortality. Chronic psychological stres

K Karla Fernanda Garcia-Ravelo

Cardiac organoids in toxicology: from construction strategies and research trends to precision screening applications

Stem Cell Res Ther. 2026 Jun 27. doi: 10.1186/s13287-026-05114-1. Online ahead of print.ABSTRACTCardiovascular diseases (CVDs) are the leading cause of death worldwide, with significant attention focused on the development of therapeutic drugs and research into pathogenic mechanisms. In the real wor

L Liya Qiao

Comparative cardiovascular efficacy of antidiabetic therapies in type 2 diabetes: a systematic review and network meta-analysis of randomized trials

Diabetol Metab Syndr. 2026 Jun 27. doi: 10.1186/s13098-026-02226-9. Online ahead of print.ABSTRACTBACKGROUND: Cardiovascular diseases (CVDs) remain the leading cause of morbidity and mortality among individuals with type 2 diabetes mellitus (T2DM), imposing a substantial burden on healthcare systems

D Donya Mohammadi

Identification of a novel pathogenic variant in MYLK in an Iranian family with non-syndromic familial aortic aneurysm and dissection by whole-exome sequencing and literature review

BMC Med Genomics. 2026 Jun 27. doi: 10.1186/s12920-026-02419-1. Online ahead of print.ABSTRACTBACKGROUND: Non-syndromic familial thoracic aortic aneurysm and dissection (ns-FTAAD) is an inherited disease that follows an autosomal dominant pattern; however, pinpointing the responsible genes is often

H Hamide Jafari

Aging with burden: multimorbidity, depression and quality of life in older adults residing in long-term care facilities in South Africa

BMC Geriatr. 2026 Jun 27. doi: 10.1186/s12877-026-07846-4. Online ahead of print.ABSTRACTBACKGROUND: Population ageing has become an immediate global imperative, with older adults disproportionately afflicted by multimorbidity, a complex interplay of co-existing chronic diseases that erodes health-r

S Shane Naidoo

Longitudinal changes and cumulative exposure of cardiometabolic index predict cardiovascular disease risk in middle-aged and older adults: a national prospective cohort study

BMC Cardiovasc Disord. 2026 Jun 27. doi: 10.1186/s12872-026-06101-3. Online ahead of print.ABSTRACTBACKGROUND: Cardiovascular disease (CVD) remains the leading cause of morbidity and mortality among aging populations. Single-time-point risk assessments may not reflect dynamic cardiometabolic changes

X Xiaoyun Liu

Zinc deficiency in patients with type 2 diabetes increases risk of cardiovascular diseases: Tehran Lipid and Glucose Study

BMC Cardiovasc Disord. 2026 Jun 27. doi: 10.1186/s12872-026-06182-0. Online ahead of print.ABSTRACTBACKGROUND AND AIM: This study aimed to assess the prospective association between zinc (Zn) deficiency and the risk of cardiovascular diseases (CVD), CVD mortality and all-cause mortality in adults wi

Z Zahra Bahadoran

Diastolic echocardiographic parameters identify pediatric kidney transplant recipients with structural myocardial alterations

Pediatr Nephrol. 2026 Jun 27. doi: 10.1007/s00467-026-07416-1. Online ahead of print.ABSTRACTBACKGROUND: Cardiac complications are among the most common causes of death in patients after pediatric kidney transplantation (KTx), but defined diagnostic procedures identifying young patients at risk are

J Jeannine von der Born

Diffusion of carbon monoxide in the lungs and pulmonary artery pressures in school aged children who were born preterm

CONCLUSION: Low K(CO) was associated with higher SPAP and MPAP and lower FEV(1)/FVC in school-aged children born premature. We speculate early and serial assessments of lung function with K(CO) may identify subjects born preterm at high risk for pulmonary hypertension who would benefit from cardiac

C Christopher Harris

Deep learning and red deer optimiser for automatic cardiovascular disease identification on magnetic resonance images

Sci Rep. 2026 Jun 27. doi: 10.1038/s41598-026-55595-6. Online ahead of print.ABSTRACTMagnetic Resonance Imaging (MRI) is a non-invasive imaging method that can give detailed visualization of the cardiac structures and blood flow, which is effective in diagnosis of cardiovascular diseases (CVDs). It

A Ajeet Singh

AI-enhanced ECG for acute coronary syndrome triage: A state-of-the-art review

Cardiovasc Revasc Med. 2026 Jun 24:S1553-8389(26)00281-2. doi: 10.1016/j.carrev.2026.06.015. Online ahead of print.ABSTRACTAcute coronary syndrome (ACS) remains a leading cause of emergency department presentations, yet triage based on the ST-elevation myocardial infarction (STEMI)/non-ST-elevation

K Keshav Garg

Complex Patent Foramen Ovale: Anatomic Variants, Technical Considerations, and Outcomes

J Cardiothorac Vasc Anesth. 2026 Jun 4:S1053-0770(26)00478-7. doi: 10.1053/j.jvca.2026.06.006. Online ahead of print.ABSTRACTPatent foramen ovale (PFO) closure is a common intervention aimed at reducing recurrent stroke in patients with cryptogenic embolism. Complex PFO anatomies, characterized by f

S Sant Kumar

Energy beats: Daily and circadian rhythms in mitochondrial biology

Mitochondrion. 2026 Jun 27:102191. doi: 10.1016/j.mito.2026.102191. Online ahead of print.ABSTRACTCircadian rhythms orchestrate a wide array of behavioral and physiological functions, coordinating cellular and organismal processes on an approximately 24-h cycle through an intrinsic timekeeping syste

N Nadia Ceccato

Association between Thrombus Neutrophil Extracellular Traps Content and Ischemic Stroke Recurrence

J Thromb Haemost. 2026 Jun 27:S1538-7836(26)00413-7. doi: 10.1016/j.jtha.2026.06.028. Online ahead of print.ABSTRACTBACKGROUND: Neutrophil extracellular traps (NETs) are key mediators of immunothrombosis that link inflammation and coagulation. Although the presence of NETs within retrieved thrombi h

H Hyungwoo Lee

Finerenone: a next-generation nonsteroidal mineralocorticoid receptor antagonist reshaping the management of cardiovascular and metabolic diseases

Biochem Pharmacol. 2026 Jun 27:118201. doi: 10.1016/j.bcp.2026.118201. Online ahead of print.ABSTRACTCardiovascular diseases (CVDs) remain a leading cause of global mortality, necessitating novel therapeutic strategies. Mineralocorticoid receptor (MR) overactivation drives pathological inflammation,

H Heng Zhang

Marijuana Use and Acute Myocardial Infarction: Mechanistic Insights, Clinical Implications, and Emerging Challenges

Am J Med. 2026 Jun 27:S0002-9343(26)00491-2. doi: 10.1016/j.amjmed.2026.06.014. Online ahead of print.ABSTRACTMarijuana, or cannabis, is the most commonly used illicit substance in the United States, with prevalence nearly doubling over the past decade. Accumulating evidence implicates cannabis use

S Sarib Sultan

ACSS2 promotes macrophage senescence and atherosclerosis by upregulating histone H3 lysine 9 crotonylation

Biochim Biophys Acta Mol Basis Dis. 2026 Jun 27:168336. doi: 10.1016/j.bbadis.2026.168336. Online ahead of print.ABSTRACTAtherosclerosis (AS) is an aging-related chronic inflammatory disease. Histone lysine crotonylation (Kcr) is a posttranslational modification, which is widespread as acetylation;

Q Quanwen Yin

Iridoids in medicinal herbs for the treatment of cardiovascular diseases: Ethnopharmacology, phytochemistry, and pharmacology

J Ethnopharmacol. 2026 Jun 27:122112. doi: 10.1016/j.jep.2026.122112. Online ahead of print.ABSTRACTETHNOPHARMACOLOGICAL RELEVANCE: Cardiovascular diseases (CVDs) remain a major challenge to global public health. Although various pharmacological and surgical interventions are available, their long-t

H Huiyue Yuan

Time-dependent circulating metabolic changes and key regulatory pathways in Alzheimer's disease: A combined animal model and public database study

Exp Gerontol. 2026 Jun 27:113216. doi: 10.1016/j.exger.2026.113216. Online ahead of print.ABSTRACTEarly diagnosis remains a major challenge in Alzheimer's disease (AD), as clinical symptoms often appear after irreversible pathological progression. This study aimed to identify early diagnostic biomar

X Xiangjie Qiu

Development of a single-item patient-reported measure of treatment side-effect burden in clinical trials of rheumatic and musculoskeletal diseases using stakeholder input and large language model refinement

Semin Arthritis Rheum. 2026 Jun 19;79:153026. doi: 10.1016/j.semarthrit.2026.153026. Online ahead of print.ABSTRACTOBJECTIVES: To build on existing evidence regarding single-item measurement instruments of patient-reported bother or trouble from medical side effects in individuals with rheumatic and

D Dorthe B Berthelsen

Post-stroke endothelial cell plasticity: A transformational lineage from complete to partial EndoMT

Tissue Cell. 2026 Jun 26;103:103729. doi: 10.1016/j.tice.2026.103729. Online ahead of print.ABSTRACTThe internationalization of vascular endothelial cells has been established to promote the development and progression of ischemic stroke. Research indicates that endothelial-mesenchymal transition (E

S Siyi Tang

Cardiac organoids bridge translational gaps in 3R-compliant safety testing

Stem Cell Res. 2026 Jun 25;95:104039. doi: 10.1016/j.scr.2026.104039. Online ahead of print.ABSTRACTCardiotoxicity remains a leading cause of late-stage drug attrition and post-marketing withdrawal, underscoring persistent limitations in current preclinical safety assessment paradigms. Traditional a

C Cyrielle Jajkiewicz

Polycaprolactone and poly(vinyl alcohol) electrospun single-layer nanofiber materials loaded with novel antibacterial LEGO-LPPO for advanced wound dressing

Biomater Adv. 2026 Jun 22;188:215039. doi: 10.1016/j.bioadv.2026.215039. Online ahead of print.ABSTRACTWound infection remains a major obstacle to effective healing and highlights the need for advanced dressings that combine antimicrobial activity with favorable biological properties. In this study,

N Nitjawan Sahatsapan

Nutrients and bioactive compounds in nuts: implications for human health

Food Chem. 2026 Jun 2;523:149828. doi: 10.1016/j.foodchem.2026.149828. Online ahead of print.ABSTRACTNuts (tree nuts and peanuts) are nutrient-dense foods, rich in unsaturated fatty acids and fibre, micronutrients such as non‑sodium minerals and vitamins, bioactive non-nutritive compounds such as po

C Cesarettin Alasalvar