New-onset sexual dysfunction in men: cardiometabolic associations and a practical outpatient approach

Cas Lek Cesk. 2026;165(3-4):146-151.ABSTRACTNew-onset sexual dysfunction in men, particularly erectile dysfunction, should not be regarded merely as an isolated sexual complaint. It may represent an early manifestation of endothelial dysfunction, atherosclerotic disease, diabetes mellitus type 2, ob

M Marek Broul

Subclinical carotid atherosclerosis in inflammatory bowel disease: a population-based cross-sectional study

BMJ Open Gastroenterol. 2026 Aug 14;13(1):e002278. doi: 10.1136/bmjgast-2026-002278.ABSTRACTOBJECTIVE: Patients with inflammatory bowel disease (IBD) have an increased risk of cardiovascular and cerebrovascular events, but the underlying mechanisms remain unclear. We aimed to assess subclinical caro

A Alexander Akhgar

Major cardiovascular events in Japanese patients with acute and chronic coronary syndrome

Open Heart. 2026 Aug 14;13(2):e004247. doi: 10.1136/openhrt-2026-004247.ABSTRACTBACKGROUND: Cardiovascular (CV) disease remains the second leading cause of mortality in Japan, yet real-world estimates of recurrent CV risk across acute coronary syndrome (ACS) and chronic coronary syndrome (CCS) pheno

N Nobuhiro Osada

Electrical cardioversion for atrial fibrillation: nationwide trends in Denmark, 2010-2022

Open Heart. 2026 Aug 14;13(2):e004083. doi: 10.1136/openhrt-2026-004083.ABSTRACTBACKGROUND: Electrical cardioversion (ECV) is widely used for restoring sinus rhythm in atrial fibrillation (AF). However, population-level trends in use of ECV in individuals with AF remain poorly characterised.AIM: We

L Lars Frost

Re-evaluating pharmaceutical stability in space: A biomedical and regulatory science framework for long-duration missions

Life Sci Space Res (Amst). 2026 Sep;52:45-51. doi: 10.1016/j.lssr.2026.07.002. Epub 2026 Jul 12.ABSTRACTPharmaceutical stability is a critical determinant of crew health and mission success in long-duration spaceflight. Current regulatory frameworks governing drug stability are primarily based on te

J Ju Eun Seol

A systematic mapping review of studies reporting the effects of spaceflight on cardiovascular outcomes

Life Sci Space Res (Amst). 2026 Sep;52:37-44. doi: 10.1016/j.lssr.2026.07.003. Epub 2026 Jul 6.ABSTRACTThis systematic review aimed to characterize the landscape of cardiovascular research in the context of spaceflight and its Earth-based analogs. In collaboration with subject matter experts from th

M Mattias Neset

UHAB-1: Physiological responses to a 48-hour spaceflight analog mission underwater

Life Sci Space Res (Amst). 2026 Sep;52:146-153. doi: 10.1016/j.lssr.2026.02.006. Epub 2026 Feb 17.ABSTRACTUnderwater habitats (UHABs) are a promising research platform to investigate human performance in spaceflight because they combine isolation, confinement, limited physical activity, and technica

F Fabian N Möller

Hauora Manawa mo nga Kaumatua me nga Whanau: a co-designed community-based cohort study of cardiovascular health among older Maori in Canterbury, New Zealand-a study protocol

BMJ Open. 2026 Aug 14;16(8):e120784. doi: 10.1136/bmjopen-2026-120784.ABSTRACTINTRODUCTION: Cardiovascular disease remains a leading cause of preventable mortality in Aotearoa New Zealand (NZ), with Māori continuing to experience earlier onset, higher hospitalisation rates and greater mortality than

A Andree Pearson

Methadone administration and QT interval prolongation: protocol for a systematic review and meta-analysis

BMJ Open. 2026 Aug 14;16(8):e118322. doi: 10.1136/bmjopen-2026-118322.ABSTRACTINTRODUCTION: Methadone is a long-acting opioid used to treat opioid use disorder, cancer pain and provide perioperative analgesia. Methadone administration has been associated with QTc interval prolongation and consequent

E Eduardo Nunez-Rodriguez

Interplay of patent foramen ovale and atrial septum aneurysm in a nonagenarian patient presenting with platypnoea-orthodeoxia syndrome

BMJ Case Rep. 2026 Aug 14;19(8):e271548. doi: 10.1136/bcr-2025-271548.ABSTRACTPatent foramen ovale (PFO) is a common congenital cardiac anomaly, generally responsible for cryptogenic stroke. Still, it can cause severe positional hypoxia via a right-to-left shunt if associated with anatomic distortio

D Dhan Bahadur Shrestha

Astragalus polysaccharide relieves chronic intermittent hypoxia-induced vascular endothelial dysfunction by inhibiting ferroptosis through activation of the Nrf2/SLC7A11/GPX4 axis

Eur J Pharmacol. 2026 Aug 14:179255. doi: 10.1016/j.ejphar.2026.179255. Online ahead of print.ABSTRACTBACKGROUND: Vascular endothelial dysfunction (VED) is pivotal in diverse disorders, and ferroptosis (iron-dependent regulated cell death) is linked to cardiovascular diseases. Astragalus polysacchar

S Susu Wu

PPARα deficiency exacerbates atherosclerosis progressing through enhancing pTh17 cells-macrophage crosstalk

Eur J Pharmacol. 2026 Aug 14:179247. doi: 10.1016/j.ejphar.2026.179247. Online ahead of print.ABSTRACTAtherosclerosis (AS) is a chronic inflammatory disease driven by hypercholesterolemia and characterized by the accumulation of lipid-rich plaques within arterial walls. Although the nuclear receptor

T Tong Ren

Whole heart non-contrast 4D Flow MRI at 3.0T for clinical follow-up of congenital heart disease in children and adolescents

J Cardiovasc Magn Reson. 2026 Aug 14:102786. doi: 10.1016/j.jocmr.2026.102786. Online ahead of print.ABSTRACTAIMS: Cardiac MRI is central to evaluating ventricular function and hemodynamics in pediatric congenital heart disease (CHD). Conventional two-dimensional phase-contrast (2D-PC) imaging is ch

J J van Schuppen

Left Ventricular Mass is Associated with Biopsy-Assessed Renal Fibrosis in Chronic Kidney Disease

J Cardiovasc Magn Reson. 2026 Aug 14:102790. doi: 10.1016/j.jocmr.2026.102790. Online ahead of print.ABSTRACTBACKGROUND: Left ventricular remodeling predicts cardiovascular mortality in chronic kidney disease (CKD). Prior studies have linked renal functional markers to cardiac structural changes, bu

C Carl G Glessgen

Enhancing Anthocyanin Bioavailability Unlocks the Cardiovascular Potential of Grape Pomace: A Review

J Nutr. 2026 Aug 14:101784. doi: 10.1016/j.tjnut.2026.101784. Online ahead of print.ABSTRACTGrape pomace (GP) is a major byproduct of the wine industry, rich in bioactive compounds such as polyphenols, anthocyanins (ACYs), and fiber, all of which have important functional properties. GP is composed

C Cherishma Chowdary Ghanta

Reduced Occludin expression in aortic endothelial cells mediates endothelial barrier dysfunction in aortic dissection

Biochim Biophys Acta Mol Basis Dis. 2026 Aug 14:168417. doi: 10.1016/j.bbadis.2026.168417. Online ahead of print.ABSTRACTAortic dissection (AD) is a catastrophic cardiovascular emergency, yet the mechanisms underlying early endothelial barrier dysfunction in AD remain poorly understood. This study i

S Shiqi Gao

Efficacy of Probiotic and Synbiotic Supplementation on Antibiotic Use Duration and Risk of Postoperative Infection in Patients Undergoing Gastrointestinal and Cancer-Related Surgery: An Umbrella Review of Meta-Analyses

Clin Nutr ESPEN. 2026 Aug 14:105013. doi: 10.1016/j.clnesp.2026.105013. Online ahead of print.ABSTRACTOBJECTIVE: This umbrella review was conducted to assess the certainty and validity of all available meta-analyses for intervention trials regarding the impact of any synbiotic and probiotic interven

A Amir Hossein Zanganeh

The Association Between Reversion of Prediabetes to Normoglycemia and Incident Cardiovascular Disease and Mortality: A Systematic Review and Meta-Analysis

Can J Diabetes. 2026 Aug 14:S1499-2671(26)00160-7. doi: 10.1016/j.jcjd.2026.08.003. Online ahead of print.ABSTRACTBACKGROUND: Prediabetes affects approximately 470 million adults worldwide and is an established risk factor for cardiovascular disease. Whether reversion from prediabetes to normoglycem

N Naseem Eisa

Cleaner Air for Lower Cardiometabolic Risk: protocol for a double-blind, randomized, sham-controlled trial of HEPA filtration in adults with prediabetes

Am Heart J. 2026 Aug 14:107573. doi: 10.1016/j.ahj.2026.107573. Online ahead of print.ABSTRACTINTRODUCTION: Air pollution is a leading driver of cardiovascular disease with a growing body of literature implicating this in worse glucose homeostasis. Increases in fine particulate matter air pollution

S Sharine Wittkopp

Developmental Trajectories of Electrocardiographic Parameters in Pediatric Patients

Heart Rhythm. 2026 Aug 14:S1547-5271(26)02685-8. doi: 10.1016/j.hrthm.2026.08.013. Online ahead of print.ABSTRACTBACKGROUND: Normative pediatric electrocardiographic (ECG) parameters have been established in prior studies, but lack fine temporal resolution during early life. Accurate age-specific va

K Kazi T Haq

Nutrition and Chronic Disease Management for the Clinical Endocrinologist: Leveraging the Malnutrition-Based Chronic Disease Model

Endocr Pract. 2026 Aug 14:S1530-891X(26)01112-2. doi: 10.1016/j.eprac.2026.08.011. Online ahead of print.ABSTRACTThis paper is based on the Keynote Address at the 2026 AACE Annual Meeting on Nutrition and Chronic Disease. Nutrition is the interaction of diet and metabolism though conventional focus

J Jeffrey I Mechanick

Combinatorial perisphenoidal anatomy on CBCT: internal carotid artery, optic nerve, foramen rotundum, vidian canal, and intersphenoid sinus septum

Ann Anat. 2026 Aug 14:153357. doi: 10.1016/j.aanat.2026.153357. Online ahead of print.ABSTRACTOBJECTIVE: To assess individual and combined cone-beam CT (CBCT) relationships of the internal carotid artery (ICA), foramen rotundum (FR), optic nerve (ON), vidian canal (VC) and intersphenoid sinus septum

I Ionuţ Mădălin Munteanu

A Propensity-Score Matched ACS-NSQIP Database Analysis of Primary Anastomosis With or Without Diversion for Acute Perforated Diverticulitis

J Gastrointest Surg. 2026 Aug 14:102548. doi: 10.1016/j.gassur.2026.102548. Online ahead of print.ABSTRACTBACKGROUND: Resection with primary anastomosis (RPA) has emerged as an accepted alternative to Hartmann's procedure for acute perforated diverticulitis with peritonitis, yet the need for routine

N Noam Kahana

The C Reactive Protein Albumin Lymphocyte Index Refines Prognostic Prediction after Endovascular Repair of Type B Aortic Dissection

Eur J Vasc Endovasc Surg. 2026 Aug 14:S1078-5884(26)00751-3. doi: 10.1016/j.ejvs.2026.08.002. Online ahead of print.ABSTRACTOBJECTIVE: Systemic inflammation is central to aortic wall degradation in type B aortic dissection (TBAD). This multicentre, retrospective cohort study aimed to evaluate the pr

X Xingfeng Chen