Preoperative pulmonary valve annulus diameter z score as a predictor of pulmonary regurgitation after tetralogy of Fallot repair: a retrospective cohort study

J Cardiothorac Surg. 2026 Jun 4. doi: 10.1186/s13019-026-04323-2. Online ahead of print.ABSTRACTBACKGROUND: Tetralogy of Fallot (ToF) is the most common cause of cyanotic congenital heart disease and pulmonary regurgitation (PR) remains its most frequent postoperative complication. The preoperative

P Pribadi Wiranda Busro

Longitudinal trajectories of stroke risk among Chinese adults: a four-year community screening cohort study

BMC Public Health. 2026 Jun 4. doi: 10.1186/s12889-026-27939-4. Online ahead of print.ABSTRACTBACKGROUND AND PURPOSE: Stroke remains a leading cause of death and disability worldwide, with a growing burden in China. Traditional stroke risk assessments are often static, relying on single-time point m

X Xiaoci He

Association between inflammatory burden index and erectile dysfunction: a retrospective case-control study

BMC Urol. 2026 Jun 4. doi: 10.1186/s12894-026-02215-0. Online ahead of print.ABSTRACTBACKGROUND: Erectile dysfunction (ED) is a vascular disease associated with systemic inflammation and endothelial dysfunction. The role of inflammatory markers in the pathogenesis of ED is gaining increasing importa

A Ayhan Arslan

Association of red blood cell distribution width to albumin ratio with all-cause and cardiovascular mortality among adults with MASLD

BMC Gastroenterol. 2026 Jun 4. doi: 10.1186/s12876-026-04987-z. Online ahead of print.ABSTRACTBACKGROUND: Metabolic dysfunction-associated steatotic liver disease (MASLD) is a growing global health burden. Identifying robust prognostic biomarkers is crucial for early risk stratification. The red blo

Z Ze-Bin Ni

Translation, adaptation, and validation of a Moroccan version of the H-SCALE (Hypertension Self-Care Activity Level effects) for hypertensive patients

BMC Prim Care. 2026 Jun 4. doi: 10.1186/s12875-026-03400-8. Online ahead of print.ABSTRACTBACKGROUND: Hypertension is the leading cause of premature death worldwide and the primary risk factor for cardiovascular disease. Its management relies mainly on self-management practices by hypertensive patie

M Manar Aarrad

Preliminary exploration of dynamic changes in circulating mitochondrial DNA (ΔmtDNA) as a prognostic biomarker for acute ST-segment elevation myocardial infarction patients: a prospective observational study

BMC Cardiovasc Disord. 2026 Jun 5. doi: 10.1186/s12872-026-06048-5. Online ahead of print.ABSTRACTBACKGROUND: Mitochondrial DNA (mtDNA) likely contributes to myocardial ischemia-reperfusion injury, yet the prognostic value of its dynamic changes (ΔmtDNA) for major adverse cardiovascular events (MACE

S Shipeng Tian

Association of a novel Fat-Muscle-BMI Index (FMBI) with NAFLD, liver fibrosis, and atherosclerotic cardiovascular disease risk: a cross-sectional study in 1,592 Chinese adults

BMC Gastroenterol. 2026 Jun 5. doi: 10.1186/s12876-026-04983-3. Online ahead of print.ABSTRACTBACKGROUND: Non-alcoholic fatty liver disease (NAFLD) is a global burden with unmet non-invasive biomarker needs; BMI and FMRs have limitations, and their combined index FMBI is unstudied. We aim to explore

X Xiaokang Wu

The exploration to identify key molecules in the interaction between endothelial cells and mono-macrophages in atherosclerosis based on the single cell transcriptome

BMC Cardiovasc Disord. 2026 Jun 5. doi: 10.1186/s12872-026-06031-0. Online ahead of print.ABSTRACTCoronary artery disease (CAD) is the leading cause of global cardiovascular deaths, and atherosclerosis (AS) is the characteristic pathological change in CAD. The interactions between monocytes/macropha

B Boyu Li

Seven-year experience (2018-2025) of a hospital-based cardiovascular tissue bank in Israel: operational insights and clinical impact

Cell Tissue Bank. 2026 Jun 5;27(3):29. doi: 10.1007/s10561-026-10230-6.ABSTRACTCryopreserved human heart valves and cardiovascular tissues (homografts) are essential for the surgical treatment of congenital and acquired valvular diseases, particularly in pediatric patients, where prosthetic options

A Alina Levy

AAV gene therapy for homozygous familial hypercholesterolemia: a phase 1 trial

Nat Med. 2026 Jun 4. doi: 10.1038/s41591-026-04441-3. Online ahead of print.ABSTRACTHomozygous familial hypercholesterolemia (HoFH) is a rare autosomal disease characterized by severely elevated low-density lipoprotein cholesterol (LDL-C) levels and accelerated atherosclerotic cardiovascular disease

T Tao Zheng

Urinary vesicle biomarkers and kidney function-results from the German AugUR study

Sci Rep. 2026 Jun 4;16(1):17350. doi: 10.1038/s41598-026-56331-w.ABSTRACTProgression into more severe stages of chronic kidney disease (CKD) based on estimated glomerular filtration rate (eGFR) and albuminuria are associated with increased risk of end-stage renal failure, cardiovascular diseases, an

L Luisa Schnobrich

PDRG1 induced by SP1 facilitates the proliferation and metastasis of hepatocellular carcinoma by activating the Wnt/β-catenin pathway

MedScience. 2026 Jun 5. doi: 10.1007/s11684-026-1237-8. Online ahead of print.ABSTRACTHepatocellular carcinoma (HCC) remains a lethal malignancy with limited therapeutic targets. P53 and DNA damage-regulated gene 1 (PDRG1) has emerged as an oncogene in multiple cancers, yet its role and regulatory m

X Xudong Zhao

Impact of a Telehealth Navigator Intervention on Hypertension Control Among Black Patients Served by Federally Qualified Health Centers

J Gen Intern Med. 2026 Jun 4. doi: 10.1007/s11606-026-10559-4. Online ahead of print.ABSTRACTBACKGROUND: Hypertension-a leading cardiovascular disease risk factor-disproportionately impacts Black individuals in part due to inequities in access to quality, coordinated health care.OBJECTIVE: To evalua

K Kenneth N Lim

The potential of bioengineered exosomes in regenerative medicine: a next generation therapy

Hum Cell. 2026 Jun 5;39(6):86. doi: 10.1007/s13577-026-01400-5.ABSTRACTThe limitations of conventional drug delivery systems and synthetic nanocarriers have spurred the search for advanced therapeutic platforms in regenerative medicine. Bioengineered exosomes/sEV, natural extracellular vesicles with

S Shiwani Kumari

Multi-omics profiling reveals EMT-driven fibroblast activation in the renal injury niche

Cell Mol Life Sci. 2026 Jun 5. doi: 10.1007/s00018-026-06226-w. Online ahead of print.ABSTRACTPersistent renal injury creates conditions for activating fibroblasts. However, due to the complexity of the renal injury microenvironment, the mechanisms driving fibroblast activation remain poorly underst

S Songmei Zhai

Renal function and cardiovascular events in predialysis care

Sci Rep. 2026 Jun 4. doi: 10.1038/s41598-026-54285-7. Online ahead of print.ABSTRACTCardiovascular events (CVE) are highly prevalent in chronic kidney disease (CKD), with risk increasing as CKD progresses. Whether renal function remains associated with CVE in advanced CKD is uncertain. We evaluated

B Beatriz Escamilla-Cabrera

Food inflammation index and risks of all-cause and cardiovascular mortality among individuals with cardiovascular-kidney-metabolic syndrome: a nationally representative cohort study from NHANES 1999-2018

Sci Rep. 2026 Jun 4. doi: 10.1038/s41598-026-56498-2. Online ahead of print.ABSTRACTEvidence on the association between the Food Inflammation Index (FII) and mortality risk in individuals with cardiovascular-kidney-metabolic syndrome (CKM) remains limited. This study examined the associations of the

G Guanhua Li

Colchicine use after acute myocardial infarction is associated with reduced dialysis dependence in advanced chronic kidney disease

Sci Rep. 2026 Jun 4. doi: 10.1038/s41598-026-54682-y. Online ahead of print.ABSTRACTEvidence-based treatments to improve renal outcomes in patients with advanced chronic kidney disease (CKD) after acute myocardial infarction (AMI) are limited. We aimed to evaluate the clinical effects of colchicine

C Cheng-Chun Wei

Food environment and cardiovascular kidney metabolic diseases mortality

NPJ Sci Food. 2026 Jun 4. doi: 10.1038/s41538-026-00918-0. Online ahead of print.ABSTRACTCardiovascular, kidney, and metabolic (CKM) diseases are leading causes of mortality in the United States (US), with geographic and socioeconomic disparities. The community food environment, including food acces

X Xiaowen Wang

Dynamics of the β-cardiac myosin auto-inhibited state explain cardiomyopathy pathogenesis

Nat Commun. 2026 Jun 4. doi: 10.1038/s41467-026-73572-5. Online ahead of print.ABSTRACTCardiac contractility requires precise regulation. A recently discovered form of regulation of cardiac contractility involves a β-cardiac myosin off-state, the Interacting-Heads Motif (CarIHM). Despite its central

D Daniel Auguin

Sleep disorders reshape the cardiovascular risk prediction value of systemic inflammation: a NHANES cohort study (2005-2018)

Nutr Metab Cardiovasc Dis. 2026 May 13:104800. doi: 10.1016/j.numecd.2026.104800. Online ahead of print.ABSTRACTBACKGROUND AND AIM: Sleep disorders (SD) are a known cardiovascular risk factor, with systemic inflammation implicated as a potential pathway. However, whether inflammation mediates or mod

Y Yuan Zhou

Cardiovascular complications in patients with myeloproliferative neoplasms: What hematologists need to know

Semin Hematol. 2026 May 14:S0037-1963(26)00048-X. doi: 10.1053/j.seminhematol.2026.05.005. Online ahead of print.ABSTRACTPatients with myeloproliferative neoplasms (MPNs), including essential thrombocythemia, polycythemia vera, and myelofibrosis, are at increased risk of cardiovascular disease and c

O Orly Leiva

Prediction of the Statin responders with radiomics

J Cardiovasc Comput Tomogr. 2026 Jun 4:S1934-5925(26)00105-X. doi: 10.1016/j.jcct.2026.05.010. Online ahead of print.ABSTRACTBACKGROUND: Statins are a cornerstone medication for coronary atherosclerosis. This study assessed whether radiomic analysis of coronary computed tomography angiography (CCTA)

S Sang-Eun Lee

Glucocorticoid resistance-induced inflammation drives cardiovascular-kidney-metabolic (CKM) syndrome pathophysiology

Trends Endocrinol Metab. 2026 Jun 4:S1043-2760(26)00123-2. doi: 10.1016/j.tem.2026.05.004. Online ahead of print.ABSTRACTProlonged activation of the hypothalamic-pituitary-adrenal axis results in excessive secretion of the glucocorticoid (GC) hormone cortisol, which contributes to weight gain, incre

G Genesee J Martinez