Differential associations of transient hyperuricemia and transient hypouricemia with annual changes in estimated glomerular filtration rate in healthy participants: an observational study

BMC Nephrol. 2026 Mar 6. doi: 10.1186/s12882-026-04875-4. Online ahead of print.ABSTRACTBACKGROUND: Dysuricemia, encompassing both hyperuricemia (serum uric acid: SUA > 7 mg/dl) and hypouricemia (SUA ≤ 3 mg/dL), has been linked to cardio-renal risks, but it remains unclear whether consistent or tran

N Naoyuki Otani

TREM2 in neurodegeneration and diseases

Mol Psychiatry. 2026 Mar 6. doi: 10.1038/s41380-026-03505-7. Online ahead of print.ABSTRACTTriggering receptor expressed on myeloid cells 2 (TREM2) is a cell surface transmembrane receptor from the TREM receptor family, predominantly expressed on the microglia in the central nervous system (CNS). TR

A Altaf A Abdulkhaliq

Dietary restriction in aging and longevity

Nat Aging. 2026 Mar 6. doi: 10.1038/s43587-026-01091-5. Online ahead of print.ABSTRACTDifferent types of dietary restriction (DR) have been practiced by humans for religious and medical purposes for millennia, but only during the past three decades has the scientific study of DR at cellular and mole

T Tomas Schmauck-Medina

A multi-site analysis of advanced age and elevated glucose predicting composite cardiovascular events in patients with type II diabetes mellitus in Central Ethiopia: A five-year retrospective cohort study

J Natl Med Assoc. 2026 Feb 14:S0027-9684(26)00029-5. doi: 10.1016/j.jnma.2026.02.005. Online ahead of print.ABSTRACTBACKGROUND: Cardiovascular disease (CVD) is the leading cause of morbidity and mortality among patients with type 2 diabetes mellitus (T2DM). Advanced age and poor glycemic control are

S Sintayehu Samuel Lorato