Variants in CEP135 Cause Congenital Microcephaly and Primary Ciliary Dyskinesia

Pediatr Pulmonol. 2026 Oct;61(10):e71866. doi: 10.1002/ppul.71866.ABSTRACTINTRODUCTION: Primary ciliary dyskinesia (PCD), a disorder of motile ciliary dysfunction causing chronic respiratory infections, may also rarely present with aspects of non-motile ciliary dysfunction, including retinitis, cent

A Abigail Bergman-Sieger

Longitudinal Impact of Pseudomonas aeruginosa Versus Haemophilus influenzae Colonization on Lung Function Decline in Children With Primary Ciliary Dyskinesia

Pediatr Pulmonol. 2026 Oct;61(10):e71861. doi: 10.1002/ppul.71861.ABSTRACTBACKGROUND: The association of Pseudomonas aeruginosa (PsA) and Haemophilus influenzae (HI) colonization with lung function in children with primary ciliary dyskinesia (PCD) remains insufficiently defined. We aimed to compare

Ö Ömer Faruk İpek

Loss of function variants in ADAMTS6: a new connective tissue disorder with heart defect, aortic aneurysm and neurodevelopmental features

Genet Med. 2026 Oct 3:102741. doi: 10.1016/j.gim.2026.102741. Online ahead of print.ABSTRACTPURPOSE: Marfan syndrome, Loeys-Dietz syndrome, and heritable thoracic aortic aneurysms and dissections (hTAAD) are autosomal dominant connective-tissue disorders with overlapping features and considerable ge

J Júlia Huguet Herrero

Effectiveness of video-enhanced educational intervention for fluid management on knowledge, practice, and adherence among patients undergoing hemodialysis: A randomized controlled trial

J Educ Health Promot. 2026 Aug 31;15:383. doi: 10.4103/jehp.jehp_434_26. eCollection 2026.ABSTRACTBACKGROUND: Fluid management remains a cornerstone of hemodialysis care; however, suboptimal adherence frequently precipitates life-threatening complications, including hypertension and cardiovascular m

S S Hepsi Prabha

Health-related quality of life among patients with type 2 diabetes mellitus using EuroQol five-dimension five level: A cross-sectional study from an urban health training center, Coimbatore, India

J Educ Health Promot. 2026 Aug 31;15:381. doi: 10.4103/jehp.jehp_27_26. eCollection 2026.ABSTRACTBACKGROUND: Diabetes mellitus significantly impacts health-related quality of life (HRQoL). Data from urban primary care settings in South India remain limited. This study assessed HRQoL among type 2 dia

S Suganathan Soundararajan

Identification of Risk Factors and Prediction Models for Acute Kidney Injury in Hospitalized Elderly Patients with Heart Failure

Clin Interv Aging. 2026 Sep 29;21:623634. doi: 10.2147/CIA.S623634. eCollection 2026.ABSTRACTBACKGROUND: Elderly heart failure (HF) patients have an increased risk of acute kidney injury (AKI) during hospitalization. Identifying risk factors and developing a prediction model are clinically important

M Mingyu Liu

Impact of Inflammatory Bowel Disease on Outcomes After Coronary Interventions: A Systematic Review and Meta-Analysis

Cureus. 2026 Sep 3;18(9):e115696. doi: 10.7759/cureus.115696. eCollection 2026 Sep.ABSTRACTInflammatory bowel disease (IBD) is associated with an elevated long-term cardiovascular risk through chronic systemic inflammation, yet whether it adversely affects outcomes following coronary revascularizati

S Sariyah Fatima

Optimization of the Sequence of Computed Tomography Angiography and Perfusion in One-Stop-Shop CT Imaging for Acute Ischemic Stroke

Med Sci Monit. 2026 Oct 4;32:e952875. doi: 10.12659/MSM.952875.ABSTRACTBACKGROUND In the "one-stop-shop" stroke computed tomography (CT) scanning protocol, CT perfusion (CTP) can be performed either before or after CT angiography (CTA). This study analyzed the effect of different scanning strategies

B Bo Gao

Association between route of nutrition and serum I-FABP and MMP-9 levels in critically ill patients with acute ischemic stroke: a prospective cohort study

Ann Saudi Med. 2026 Sep-Oct;46(5):376-387. doi: 10.5144/0256-4947.2026.376. Epub 2026 Oct 1.ABSTRACTBACKGROUND: Gut barrier dysfunction and neuroinflammation are increasingly recognised as linked pathophysiological processes in acute ischaemic stroke (AIS). However, the influence of nutritional rout

N Nurhayat Tugra Ulema

Sex, Racial/Ethnic, and Regional Disparities in Mortality Involving Both Cardiac Arrest and Type 2 Diabetes Mellitus Among U.S. Adults, 1999-2020

J Racial Ethn Health Disparities. 2026 Oct 3. doi: 10.1007/s40615-026-03215-4. Online ahead of print.ABSTRACTAIMS: Type 2 Diabetes mellitus (T2DM) and cardiac arrest (CA) drive significant mortality and healthcare costs in the U.S., yet national trends and disparities remain unclear. This study aims

A Asma Chaudhary

The safety and tolerability of opicapone in elderly Parkinson's disease patients: a real-world, multicenter, retrospective study

J Neural Transm (Vienna). 2026 Oct 3. doi: 10.1007/s00702-026-03284-z. Online ahead of print.ABSTRACTOpicapone (OPC) is an effective add-on medication for motor fluctuations in Parkinson's disease (PD), with a favorable safety and tolerability profile. Elderly PD patients are a great proportion of t

L Lanfranco De Carolis

Metabolomic biomarkers and metabolic remodelling in genetically characterised hypertrophic cardiomyopathy: a systematic review

Metabolomics. 2026 Oct 3;22(5):164. doi: 10.1007/s11306-026-02526-1.ABSTRACTINTRODUCTION: Hypertrophic cardiomyopathy (HCM) is the most common inherited cardiomyopathy and a major cause of heart failure, malignant arrhythmias and sudden cardiac death. Although pathogenic variants in sarcomeric genes

A Ammar Hariz Ahmad Razmy

Metabolic vulnerabilities in multiple myeloma: targeting iron and amino acid metabolism to induce ferroptosis

Apoptosis. 2026 Oct 3;31(10):238. doi: 10.1007/s10495-026-02449-1.ABSTRACTCould ferroptosis, a novel cell death pathway, offer a potential therapeutic strategy for multiple myeloma (MM)? Our previous research showed that ferroptosis is suppressed in MM patients, with varying sensitivities among MM c

Q Qi Li

Statins are associated with decreased risk of disease progression and death in non-cirrhotic patients with primary biliary cholangitis

Eur J Intern Med. 2026 Oct 3:107219. doi: 10.1016/j.ejim.2026.107219. Online ahead of print.ABSTRACTBACKGROUND/AIMS: We evaluated whether statins in non-cirrhotic patients with primary biliary cholangitis (PBC) might influence disease progression, including cirrhosis development, hepatic decompensat

E Eirini I Rigopoulou

Marked Variability in Lipid Profile Reporting Among Australian Pathology Providers: A National Cross-Sectional Review of Low-Density Lipoprotein Cholesterol

Heart Lung Circ. 2026 Oct 3:S1443-9506(26)00460-9. doi: 10.1016/j.hlc.2026.05.025. Online ahead of print.ABSTRACTBACKGROUND: Lipid profiles facilitate cardiovascular risk stratification, therapeutic monitoring, and patient education. Variability in pathology reporting practices may generate confusio

J Jeff R Ma

Changing Patterns of Causes of Death in Patients With Multiple Myeloma During the Modern Therapeutic Era

Clin Lymphoma Myeloma Leuk. 2026 Sep 11:S2152-2650(26)03290-8. doi: 10.1016/j.clml.2026.09.004. Online ahead of print.ABSTRACTBACKGROUND: Therapeutic advances have substantially prolonged survival in multiple myeloma (MM). However, real-world evidence on temporal changes in causes of death remains l

A Abel Rosado-Rodriguez

Patency and functional outcomes of endovascular treatment in juxta-anastomotic venous stenosis of native arteriovenous fistulas

Nefrologia (Engl Ed). 2026 Oct;46(8):501536. doi: 10.1016/j.nefroe.2026.501536.ABSTRACTINTRODUCTION: Juxta-anastomotic venous stenosis is a frequent cause of dysfunction in native arteriovenous fistula (AVFs), compromising both maturation and long-term patency. Endovascular treatment has emerged as

I Iván Zamora

Haemodynamic and neurophysiological assessments for 2-year outcome prediction in neonates with hypoxic-ischaemic encephalopathy treated with therapeutic hypothermia: a systematic review and meta-analysis

BMJ Paediatr Open. 2026 Oct 3;10(1):e004810. doi: 10.1136/bmjpo-2026-004810.ABSTRACTOBJECTIVE: To evaluate the prognostic accuracy of amplitude-integrated electroencephalography (aEEG), cerebral near-infrared spectroscopy (cNIRS) and targeted neonatal echocardiography (TnECHO) for predicting 2-year

M Mona Noureldein

Development and Evaluation of a Trauma-Informed Women's Health Education Program for Intimate Partner Violence Survivors: A Mixed-Methods Study

Violence Vict. 2026 Oct 3:VV-2025-0100.R1. doi: 10.1891/VV-2025-0100. Online ahead of print.ABSTRACTWomen with a history of intimate partner violence (IPV) are at increased risk for cardiovascular disease, human papillomavirus (HPV), cervical cancer, and human immunodeficiency virus (HIV), which we

S Sarah Joseph

A Tribute by The Editorial Board of the American Journal of Medicine. Our Retrospective and an Interview with the Outgoing Editor, Joseph S. Alpert, MD MACP

No abstractAm J Med. 2026 Oct 3:S0002-9343(26)00678-9. doi: 10.1016/j.amjmed.2026.09.016. Online ahead of print.NO ABSTRACTPMID:42829131 | DOI:10.1016/j.amjmed.2026.09.016

R Richard D deShazo

Thrombin Generation in Critically Ill Adults: A Systematic Review of Venous Thromboembolism and Pharmacological Thromboprophylaxis

J Thromb Haemost. 2026 Oct 3:S1538-7836(26)00627-6. doi: 10.1016/j.jtha.2026.09.037. Online ahead of print.ABSTRACTBACKGROUND: Venous thromboembolism (VTE) remains an important complication in critically ill adults despite standard pharmacological thromboprophylaxis. Thrombin generation assays (TGAs

C Caseng Zhang

CRISPR-based genome editing of smooth muscle cells: Disease models, therapeutic applications, and future perspectives

Vascul Pharmacol. 2026 Oct 3:107709. doi: 10.1016/j.vph.2026.107709. Online ahead of print.ABSTRACTSmooth muscle cells (SMCs) are essential for the normal function of the cardiovascular, respiratory, gastrointestinal, and urogenital systems, and SMC dysfunction contributes to a wide range of genetic

Q Qianqian Ding

Frailty-Related Metabolic Signature in the Association Between Frailty and Coronary Artery Disease: Modification by Genetic Susceptibility

J Nutr Health Aging. 2026 Oct 3;30(12):100998. doi: 10.1016/j.jnha.2026.100998. Online ahead of print.ABSTRACTBACKGROUND: Frailty is associated with increased coronary artery disease (CAD) risk, but the circulating metabolic features underlying the frailty-CAD relationship and their interplay with g

J Junchi Liu

Chronic sleep deprivation promotes atherosclerosis via NFIL3/RORgammat Axis mediated Th17/Treg imbalance, targeting IL-17A attenuates disease progression

Int Immunopharmacol. 2026 Oct 3;190:117496. doi: 10.1016/j.intimp.2026.117496. Online ahead of print.ABSTRACTBACKGROUND: Chronic sleep deprivation (CSD) is an independent risk factor for atherosclerotic cardiovascular disease, but the underlying mechanisms remain elusive. This study aimed to investi

X Xixi Liu