PCSK9 alleviates doxorubicin‑induced pyroptosis of cardiomyocytes

Mol Med Rep. 2026 Sep;34(3):255. doi: 10.3892/mmr.2026.13965. Epub 2026 Jul 17.ABSTRACTProlonged survival of patients with cancer has increased the need to address chemotherapy‑related cardiovascular complications. Doxorubicin (DOX), a widely used anthracycline, is associated with dose‑dependent car

C Chaochu Cui

Evaluating the relationship between antidrug antibodies and efficacy and safety outcomes in patients with Fabry disease receiving enzyme replacement therapy: a systematic literature review

Orphanet J Rare Dis. 2026 Jul 16. doi: 10.1186/s13023-026-04438-8. Online ahead of print.ABSTRACTBACKGROUND: Fabry disease is a lysosomal storage disorder caused by deficient activity of the enzyme α-galactosidase A, resulting in progressive accumulation of globotriaosylceramide (Gb3) and widespread

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Association between the combined cholesterol, high-density lipoprotein, glucose index and frailty index and new-onset cardiovascular disease in individuals with cardiovascular-kidney-metabolic syndrome stages 0-3: evidence from CHARLS

Cardiovasc Diabetol. 2026 Jul 16. doi: 10.1186/s12933-026-03293-y. Online ahead of print.ABSTRACTBACKGROUND: Early-stage cardiovascular-kidney-metabolic (CKM) syndrome, encompassing stages 0-3, represents a critical window for identifying individuals at risk before the development of clinical cardio

Z Zhonghua Sun