Cologne (Germany): Institute for Quality and Efficiency in Health Care (IQWiG); 2026 Feb 22.ABSTRACTRESEARCH QUESTION: The aim of this report is toassess the benefit of diagnostics using cardiac magnetic resonance imaging as part of a diagnostic strategy, compared with a diagnostic strategy without
Biol Sex Differ. 2026 Feb 7. doi: 10.1186/s13293-026-00845-5. Online ahead of print.ABSTRACTBACKGROUND: Numerous sex differences has been described in aterosclerosis including in endothelial dysfunction. Oxidized low-density lipoproteins (ox-LDL) contribute to the formation of atherosclerotic plaque
Genome Biol. 2026 Feb 7. doi: 10.1186/s13059-026-03947-w. Online ahead of print.ABSTRACTBACKGROUND: Genetic variants that are associated with phenotypic variability, or variance quantitative trait loci (vQTLs), have been detected for multiple human traits. Gene-environment interactions can lead to d
BMC Med. 2026 Feb 7. doi: 10.1186/s12916-026-04685-3. Online ahead of print.ABSTRACTBACKGROUND: While diabetes-related complications have been widely investigated, the burden of infectious diseases across the diabetes spectrum remains relatively understudied.METHODS: We developed a Bayesian approach
No abstractBMC Endocr Disord. 2026 Feb 7. doi: 10.1186/s12902-026-02190-5. Online ahead of print.NO ABSTRACTPMID:41654777 | DOI:10.1186/s12902-026-02190-5
BMC Cardiovasc Disord. 2026 Feb 9. doi: 10.1186/s12872-026-05560-y. Online ahead of print.ABSTRACTBACKGROUND: Ischaemic heart disease remains the leading global cause of death, and is strongly linked to hypertension. However, recent data on hypertension and cardiovascular risk in Sri Lanka are limit
J Neurol. 2026 Feb 7;273(2):121. doi: 10.1007/s00415-026-13656-w.ABSTRACTBACKGROUND: The optimal timing of surgery for aneurysmal subarachnoid hemorrhage (aSAH) remains controversial. This study aims to identify the optimal surgical window within 72 h of symptom onset.METHODS: Patients with aSAH who
Mol Neurobiol. 2026 Feb 7;63(1):427. doi: 10.1007/s12035-026-05723-0.ABSTRACTCerebral ischemia/reperfusion injury (CIRI) commonly occurs during the treatment of ischemic stroke and leads to severe consequences, including neuronal death and permanent loss of motor function. Accurate differentiation b
Arch Toxicol. 2026 Feb 7. doi: 10.1007/s00204-025-04274-y. Online ahead of print.ABSTRACTPhosphorus is commonly part of the diets in developed countries, both as a natural component of protein-rich foods and as a food additive. Consumption of food containing high amounts of phosphate as a food addit
No abstractArch Toxicol. 2026 Feb 7. doi: 10.1007/s00204-026-04311-4. Online ahead of print.NO ABSTRACTPMID:41654648 | DOI:10.1007/s00204-026-04311-4
J Neurol. 2026 Feb 7;273(2):119. doi: 10.1007/s00415-026-13658-8.ABSTRACTOBJECTIVE: Our study aimed to determine the prevalence and clinical phenotypes of JAK2 pathogenic mutation carriers in the CNSR-III ischemic stroke (IS) cohort, and to develop a pre-test genetic screening model for identifying
J Neurol. 2026 Feb 7;273(2):120. doi: 10.1007/s00415-026-13660-0.ABSTRACTBACKGROUND: The hyperdense sinus sign (HDSS) is a readily identifiable non-contrast CT marker of acute thrombus in cerebral venous sinus thrombosis (CVST). We aimed to characterize HDSS associated features and prognostic signif
No abstractSci Rep. 2026 Feb 7. doi: 10.1038/s41598-026-38130-5. Online ahead of print.NO ABSTRACTPMID:41654604 | DOI:10.1038/s41598-026-38130-5
J Clin Lipidol. 2026 Jan 19:S1933-2874(26)00008-5. doi: 10.1016/j.jacl.2026.01.006. Online ahead of print.ABSTRACTBACKGROUND: While lipids are known prognostic markers in coronary heart disease (CHD), the long-term impact of cumulative low-density lipoprotein cholesterol (cum-LDL-C) and the duration
Transplant Proc. 2026 Feb 6:S0041-1345(26)00033-3. doi: 10.1016/j.transproceed.2025.11.015. Online ahead of print.ABSTRACTWhile renal transplantation significantly enhances both life expectancy and quality of life in patients with end-stage renal disease, the necessity for lifelong immunosuppressive
Eur J Intern Med. 2026 Feb 6:106736. doi: 10.1016/j.ejim.2026.106736. Online ahead of print.ABSTRACTChronic obstructive pulmonary disease (COPD) is often associated with cardiovascular disease and the both conditions share common risk factors (smoke), associated pathophysiological mechanisms (pulmon
Nefrologia (Engl Ed). 2026 Jan;46(1):501416. doi: 10.1016/j.nefroe.2026.501416.ABSTRACTBACKGROUND: Vascular endothelial growth factor (VEGF) is associated with renal pathogenesis of Fabry disease (FD). Proteomic studies have demonstrated that circulating levels of VEGF are higher in young FD patient
Toxicol Appl Pharmacol. 2026 Feb 5:117753. doi: 10.1016/j.taap.2026.117753. Online ahead of print.ABSTRACTTungsten exposure is associated with multiple cardiovascular diseases, but limited information exists on the mechanistic underpinnings of these relationships. The current study investigated the
Am Heart J. 2026 Feb 5:107369. doi: 10.1016/j.ahj.2026.107369. Online ahead of print.ABSTRACTBACKGROUND: The completeness of revascularization in patients presenting with non-ST-elevation myocardial infarction (NSTEMI) and multivessel disease (MVD) remains understudied. The SLIM trial previously dem
J Cardiol. 2026 Feb 5:S0914-5087(26)00028-6. doi: 10.1016/j.jjcc.2026.01.017. Online ahead of print.ABSTRACTBACKGROUND: Uric acid (UA) is a routinely measured biomarker linked to cardiovascular and metabolic disorders, but its role in the development of aortic aneurysm (AA) and aortic dissection (AD
Cir Esp (Engl Ed). 2026 Feb 5:800297. doi: 10.1016/j.cireng.2026.800297. Online ahead of print.ABSTRACTObesity is a complex metabolic disease associated with alterations in the gut microbiota and the metabolism of fatty acids and bile acids. Bariatric surgery can modify this axis, contributing to be
J Vasc Surg. 2026 Feb 5:S0741-5214(26)00091-1. doi: 10.1016/j.jvs.2026.02.003. Online ahead of print.ABSTRACTOBJECTIVE: Arteriovenous fistulae (AVF) are necessary for hemodialysis in patients with end-stage kidney disease (ESKD) but are frequently complicated by thrombosis, stenosis, and need for re
Lancet. 2026 Feb 4:S0140-6736(26)00097-8. doi: 10.1016/S0140-6736(26)00097-8. Online ahead of print.ABSTRACTBACKGROUND: Recombinant factor VIIa has been shown to slow bleeding in patients with intracerebral haemorrhage (ICH), but no haemostatic agent has been shown to improve clinical outcomes. We a
Semergen. 2026 Feb 6;52(4):102689. doi: 10.1016/j.semerg.2026.102689. Online ahead of print.ABSTRACTThe objective of this study was to review the clinical utility of Polygenic Risk Scores (PRS) in predicting cardiovascular risk from a primary care perspective. A structured narrative review according
