Repeated botulinum toxin injections for neurogenic thoracic outlet syndrome: A case report

Scritto il 04/08/2026
da Eren Aygun

Agri. 2026 Jul 1;38(3):202-204. doi: 10.5606/agri.2026.43. Epub 2026 Jun 25.

ABSTRACT

Neurogenic thoracic outlet syndrome (nTOS) is a condition caused by compression of the brachial plexus in the thoracic outlet, often leading to pain and paresthesia. In this article, we report a 34-year-old female patient with chronic nTOS symptoms refractory to prior management. Ultrasound-guided diagnostic blocks of the anterior scalene and pectoralis minor muscles provided significant temporary relief. Subsequent ultrasoundguided onabotulinum toxin A (BTX-A) injections into the scalene muscles resulted in near-complete symptom resolution lasting approximately six months. Over an 18-month follow-up, repeated injections at six-month intervals produced consistent clinical improvement without adverse effects. In conclusion, repeated ultrasound-guided BTX-A injections may be a safe and effective option within a multimodal treatment approach for nTOS.

PMID:42550976 | DOI:10.5606/agri.2026.43