Diabetes Metab Res Rev. 2026 Feb;42(2):e70138. doi: 10.1002/dmrr.70138.
ABSTRACT
AIMS: In recent years, various diabetic socks have been developed and introduced to help prevent diabetes related foot ulcers (DFUs). However, the question of which type of sock is most suitable for individuals with diabetes has not been adequately addressed. This review systematically explores the current evidence regarding the performance and structural properties of diabetic socks, along with a narrative analysis of commercial socks.
METHODS: Four databases, including Web of Science, PubMed/Medline, CINAHL (EBSCO), and Google Scholar, were examined, resulting in the selection of nine articles. Methodological quality of the clinical trials was assessed using the Downs and Black tool. Additionally, 17 commercially available socks were selected for analysis.
RESULTS: Among the selected articles, four were clinical trials, two mixed-design studies, and three laboratory-based investigations. The clinical studies exhibited poor quality and were unable to demonstrate significant outcomes. Laboratory-based studies indicated that functional finishes on yarns could prevent microbial growth and that the blend of fibres and the structure of the socks significantly affect the overall performance. Commercially available socks reporting new types of fibres lack clinical evidence to support their claims, complicating the understanding of their performance in people with diabetes.
CONCLUSIONS: Current evidence regarding the structure and function of diabetic socks is limited, with clinical trials characterised by poor methodological quality. Technical suggestions for diabetic sock design are based on limited evidence from laboratory-based studies, highlighting gaps in the literature. This review highlights the need for further investigation to establish the evidence base for diabetic socks in supporting diabetic foot care.
PMID:41721720 | DOI:10.1002/dmrr.70138