Sci Rep. 2026 May 16. doi: 10.1038/s41598-026-47521-7. Online ahead of print.
ABSTRACT
Cardio-Vascular Diseases (CvDs) persist as a significant mortality reason worldwide, which requires advanced risk categorization technologies that can offer custom medicine while protecting patient information. Present healthcare approaches must overcome fragmented data distribution systems, weak security measures in collaborative environments, and the ineffective processing of multi-mode clinical details. Our proposed Decentralized Federated Blockchain for Cardiovascular Intelligence (DFBCI) framework integrates the Multi-Chain Aggregation with Adaptive Consensus (MCAC) mechanism and the advanced Federated Dynamic Relational Learning (FDRL) technique to solve identified challenges. The DFBCI system enables protected cooperation between institutions through its blockchain multi-chain setup that securely combines medical data with imaging information while maintaining data integrity. The FDRL technique extracts patient temporal behavior knowledge from different modalities, which include ElectroCardioGrams (ECGs), echocardiograms, and biomarker datasets. The system executes feature extraction using Quantum-Enhanced Privacy Masking (QEPM) for security alongside non-invasive cardiac risk modeling through federated optimization and performs decentralized validation with smart contracts. Compared to standard approaches, Experimental results reveal that models achieve 19% better CvD risk prediction while reducing their convergence time by 22% and enhancing scalability by 27%. DFBCI creates powerful healthcare analytical platforms that advance secure CvD risk sorting worldwide without violating privacy rights, setting benchmark for fast, collaborative assessments.
PMID:42141004 | DOI:10.1038/s41598-026-47521-7