Sci Data. 2026 Apr 21. doi: 10.1038/s41597-026-07257-5. Online ahead of print.
ABSTRACT
Optimizing transcatheter pulmonary valve replacement (TPVR) requires biomechanical analysis of the right ventricular outflow tract (RVOT) and pulmonary artery (PA). Despite its importance for device sizing and landing zone identification, the availability of structured biomechanical datasets remains limited compared to left heart research. To address this gap, we present PULmonary artery Strain Evaluation (PULSE), a curated dataset of Finite Element (FE) simulation results capturing circumferential deformation in the RVOT and PA across different mechanical conditions. Derived from 60 patient-specific 3D anatomies reconstructed from cardiovascular magnetic resonance imaging, the dataset includes 960 FE models: 60 baseline (reference configuration) and 900 deformed configurations generated under varying internal pressures and tissue stiffness parameters. Adhering to the ASME V&V 40 standard, the models were verified through mesh analysis, experimental mechanical testing, and comparison with cardiovascular magnetic resonance images. PULSE supports the advancement of cardiovascular research by providing publicly available data for deformation analysis of the PA and RVOT, with potential applications in transcatheter pulmonary valve therapies.
PMID:42014744 | DOI:10.1038/s41597-026-07257-5