Acute coronary syndrome and coronary artery disease in wild-type transthyretin amyloid cardiomyopathy: a DIAMOND sub-study

Scritto il 17/02/2026
da Laura De Michieli

J Cardiovasc Med (Hagerstown). 2026 Feb 1;27(2):171-175. doi: 10.2459/JCM.0000000000001844. Epub 2026 Jan 30.

ABSTRACT

BACKGROUND: Patients with wild-type transthyretin amyloid cardiomyopathy (ATTRwt-CM) often have cardiovascular comorbidities, including acute coronary syndrome (ACS) and coronary artery disease (CAD).

RESULTS AND MAJOR FINDINGS: At baseline, 9% of patients had a history of ACS and this was associated with increased risk of adverse outcomes, while this was not the case for obstructive CAD without ACS. Further prospective studies are needed to corroborate these findings.

PMID:41703414 | DOI:10.2459/JCM.0000000000001844