A case of antiphospholipid syndrome complicated with hyperhomocysteinemia presenting initially with central retinal vein occlusion in a young male

Scritto il 12/03/2026
da X W Ji

Zhonghua Yan Ke Za Zhi. 2026 Mar 11;62(3):223-226. doi: 10.3760/cma.j.cn112142-20250409-00179.

ABSTRACT

A 28-year-old male presented to the ophthalmology department with decreased visual acuity in the left eye for 4 months. Four months prior, he was diagnosed with central retinal vein occlusion (CRVO) in the left eye at another hospital and received three intravitreal injections of anti-vascular endothelial growth factor (anti-VEGF) agents. Laboratory examinations revealed elevated levels of homocysteine, lupus anticoagulant (LA) 1 screening test result, LA1/LA2 ratio, and anti-β2 glycoprotein 1 antibody. The patient was treated with oral folic acid tablets, systemic anticoagulants, and additional intravitreal anti-VEGF therapy. He achieved a favorable prognosis after treatment.

PMID:41820067 | DOI:10.3760/cma.j.cn112142-20250409-00179