J Cross Cult Gerontol. 2026 Jul 1;41(3):37. doi: 10.1007/s10823-026-09585-w.
ABSTRACT
Stroke remains a major cause of disability and mortality globally, particularly among older adults in low- and middle-income countries. Integrating the 4Ms framework (What Matters, Medication, Mentation, and Mobility) into nursing-led preventive interventions offers a holistic, person-centered model for promoting healthy aging and mitigating stroke risk. This study evaluated the effectiveness of a nurse-led, age-friendly educational program, grounded in the 4Ms framework, in reducing stroke risk and enhancing health-promoting behaviors among older adults. A randomized controlled trial was conducted with 170 community-dwelling adults (≥ 60 years) attending outpatient clinics in Egypt. Participants were randomized to either a 4Ms-based educational intervention (two structured sessions and materials) or a control group receiving routine care. Outcomes were measured using the Revised Framingham Stroke Risk Profile, the Health-Promoting Lifestyle Profile II, and a stroke prevention practices questionnaire. Post-intervention, the intervention group demonstrated a significant reduction in 10-year stroke risk scores (p<.001) and significant improvements across all health-promoting behavior domains, especially physical activity, nutrition, and stress management (all p<.001). The percentage of participants with good stroke-prevention practices increased from 7.1% to 55.3%. Stroke risk was also inversely correlated with domains like health responsibility and stress management. The nurse-led educational program based on the 4Ms framework was associated with short-term improvements in reducing stroke risk indicators and improving health-promoting behaviors among older adults. Integration of age-friendly principles into preventive nursing care may offer a feasible and holistic approach for supporting healthy ageing in low-resource settings. Longer-term studies remain necessary.Trial RegistrationPan African Clinical Trials Registry (PACTR), registration number PACTR202606898663018. Registration was completed retrospectively.
PMID:42384123 | DOI:10.1007/s10823-026-09585-w