J Arrhythm. 2026 Jul 29;42(4):e70435. doi: 10.1002/joa3.70435. eCollection 2026 Aug.
ABSTRACT
Risk stratification using validated scoring systems is fundamental to contemporary cardiovascular medicine, underpinning diagnosis, treatment selection, and prognostic assessment. This review provides a comprehensive overview of the major risk scores used across a broad spectrum of cardiovascular diseases, such as atrial fibrillation, acute coronary syndrome, and others, highlighting their development, clinical applications, and evolving roles in guideline-directed care. Importantly, predictive performance alone does not guarantee clinical benefit. We therefore examine evidence from randomized implementation trials evaluating whether risk score-guided management improves clinical outcomes and discuss the future role of artificial intelligence in reshaping cardiovascular risk assessment by integrating dynamic, individualized prediction with actionable clinical decision support.
PMID:42529449 | PMC:PMC13418201 | DOI:10.1002/joa3.70435