Postepy Biochem. 2025 Nov 29;71(4):281-300. doi: 10.18388/pb.2021_628.
ABSTRACT
Despite medical advances, heart disease is now the world's biggest health problem, with a sharp rise in deaths. The most dangerous and common of these are heart attack and heart failure, which can lead to acute coronary syndromes and are very dangerous. Research into biochemical markers of heart disease is being driven by the need for earlier diagnosis. Assumptions include the ability to detect these markers early on, their high specificity for the heart muscle, and the reliability of assay results. Cardiac troponins and natriuretic peptides, which are already used as diagnostic tools, are crucial in diagnosing heart attacks and heart failure. ST-2 and h-FABP proteins show promise as diagnostic tools, but none of the markers discovered so far are ideal. The scientific literature on biomarkers of heart dysfunction highlights the concern among professionals. Research findings need further analysis. These solutions could transform global cardiology.
PMID:41504730 | DOI:10.18388/pb.2021_628