Georgian Med News. 2026 Mar;(372):153-162.
ABSTRACT
INTRODUCTION: Metabolic syndrome (MetS) is characterized by a cluster of interconnected chronic conditions - abdominal obesity, dyslipidemia, insulin resistance, and hypertension. MetS is highly prevalent among adults and is closely associated with chronic diseases, significantly increasing the risk of cardiovascular disease and type 2 diabetes. Beyond physiological changes, MetS substantially impacts quality of life, work capacity, and psychosocial well-being. In recent years, there has been growing scientific interest in non-biological factors influencing health, particularly social deprivation. Despite numerous studies on MetS, research comprehensively addressing the impact of social deprivation on quality of life remains limited. Most studies focus primarily on clinical indicators and do not fully capture aspects such as social isolation, economic inequality, educational level, and limited social support. This review systematizes the existing evidence on the relationship between social deprivation and quality of life in adults with metabolic syndrome.
AIM: to analyze literature data on the relationship between social deprivation and quality of life in adults with metabolic syndrome.
SEARCH STRATEGY: A systematic literature search was conducted using PubMed, Scopus, Web of Science, and Google Scholar, covering publications from 2015 to 2025. Keywords included "metabolic syndrome," "social deprivation," "socioeconomic factors," "and quality of life." Inclusion criteria comprised original research, systematic reviews, and meta-analyses examining associations between MetS, quality of life, and social deprivation in adults.
RESULTS: The review highlights significant reductions in physical, psychological, and social components of quality of life among individuals with MetS. The most pronounced negative outcomes were observed in individuals with low socioeconomic status and limited social support. Evidence from multiple studies indicates that social deprivation, encompassing unfavorable economic and living conditions and restricted access to resources, acts as an independent factor exacerbating the consequences of MetS.
CONCLUSIONS: This review emphasizes the importance of considering social deprivation as a critical determinant of quality of life in adults with MetS. Incorporating social factors into clinical and public health strategies may improve prevention, intervention, and management programs, ultimately enhancing health outcomes and reducing the burden of MetS. Further research is needed to develop integrated models combining biomedical and social determinants of health.
PMID:42107950