Exp Clin Transplant. 2026 Jul;24(Suppl 2):115-124. doi: 10.6002/ect.MESOT2025.O46.
ABSTRACT
OBJECTIVES: Kidney transplant has been associated with improvements in cardiac function in patients with chronic renal failure, particularly those with clinical overload. This study aimed to assess the effect of kidney transplant on echocardiographic parameters among a group of patients with established cardiac stress.
MATERIALS AND METHODS: Among 26 patients evaluated before and after kidney transplant, average age was 46.42 years. Eleven patients had fistula, and the remaining patients had other access. Echocardiographic measures, including left ventricular end -diastolic volume index, left ventricular hypertrophy, inferior vena cava collapse, and right ventricular function, were assessed. We used paired t tests to analyze changes before and after transplant.
RESULTS: After kidney transplant, a significant decrease was observed in average left ventricular end -diastolic volume index (P = .002 ) and in left ventricular hypertrophy thickness (P < .001 ). In addition, significant changes were observed in ejection fraction and left ventricular diameter. The left atrial volume index (P = .002 ), left atrial volume (P =.009 ), and size of the right ventricle (P = .046 ) all decreased significantly after transplant.
CONCLUSIONS: Kidney transplant significantly improved left ventricular volume and hypertrophy in patients with cardiac overload, although its effects on right ventricular and valvular function were less pronounced.
PMID:42538668 | DOI:10.6002/ect.MESOT2025.O46