Trends Immunol. 2026 Feb 27:S1471-4906(26)00002-5. doi: 10.1016/j.it.2026.01.002. Online ahead of print.
ABSTRACT
Macrophages are key in maintaining tissue homeostasis and controlling inflammation. To rapidly adapt their phenotype, they rely on JAK-STAT signaling pathways to convert extracellular cytokine cues into transcriptional responses. Understanding how macrophages interpret disease-associated cytokine environments is therefore key for deciphering how inflammation is resolved or sustained.
PMID:41763992 | DOI:10.1016/j.it.2026.01.002