Genetic variation in the long pentraxin PTX3 and Dectin-1 does not predispose to influenza- or COVID-19-associated pulmonary aspergillosis

Scritto il 07/08/2026
da Simon Feys

J Infect Dis. 2026 Aug 7:jiag403. doi: 10.1093/infdis/jiag403. Online ahead of print.

ABSTRACT

In this multicentric study, we found no association regarding incidence or outcome between common single nucleotide polymorphisms in PTX3 and CLEC7A and invasive pulmonary aspergillosis in patients with severe viral pneumonia. The distinct pathophysiology of virus-associated pulmonary aspergillosis warrants exploration of genetic variation in novel candidates.

PMID:42566654 | DOI:10.1093/infdis/jiag403