Clinical Characteristics of People With Extrapulmonary and Disseminated Tuberculosis: A 23-Year Retrospective Cohort Study in People Without HIV Without Pharmacological Immunosuppression

Scritto il 24/09/2026
da Brenda Aceves-Sánchez

Open Forum Infect Dis. 2026 Sep 9;13(9):ofag576. doi: 10.1093/ofid/ofag576. eCollection 2026 Sep.

ABSTRACT

In this retrospective cohort of non-HIV patients without pharmacological immunosuppression, who presented with extrapulmonary/disseminated tuberculosis, the gastrointestinal tract, lymph nodes, and genitourinary tract were the most commonly affected organs. 24-month all-cause mortality was 18%. Cardiovascular disease, central nervous system involvement, mycobacteremia, and ICU admission were independently associated with death.

PMID:42781183 | PMC:PMC13598341 | DOI:10.1093/ofid/ofag576