Angiol Sosud Khir. 2026 Jun 1;32(2):153-162. doi: 10.33029/1027-6661-2026-32-2-153-162.
ABSTRACT
BACKGROUND: Percutaneous coronary intervention (PCI) is a minimally invasive procedure that is a well-established method for treating patients with coronary artery disease. The explosive growth in the number of PCI performed over the past decade, not only in Russia but worldwide, has inevitably led to an increase in the number of complications that specialists encounter in their daily practice. The significance of the problem of thrombotic complications during coronary artery stenting is difficult to overestimate. This review focuses on two of the most significant and actively studied complications - stent thrombosis and radial artery occlusion - as their minimization directly impacts long-term treatment outcomes.
OBJECTIVE: To analyze data on the key risk factors, pathogenesis, and prevention strategies for stent thrombosis and radial artery occlusion in patients undergoing PCI.
METHODS: A literature analysis was conducted using the PubMed, the Cochrane Library, and Google Scholar databases.
RESULTS: The results of this study allow for a systematic assessment of the causes, predisposing conditions, and prevention methods for stent thrombosis and radial artery occlusion. For stent thrombosis, three main groups of risk factors were identified: procedural, patient-related, and pharmacological. For radial artery occlusion, predictors related to both the patient and the procedure were identified. The efficacy of intravascular imaging in reducing the incidence of stent thrombosis and the use of distal radial access in reducing the incidence of radial artery occlusion were demonstrated.
CONCLUSION: The problem of minimizing various thrombotic complications during coronary stenting remains highly relevant even against the background of improved PCI technologies, the introduction of modern tools and pharmacotherapy. A promising area is the development of validated prognostic models that integrate clinical, anatomical, and genetic factors.
PMID:42732614 | DOI:10.33029/1027-6661-2026-32-2-153-162