Adv Gerontol. 2026;39(3):365-370. doi: 10.34922/AE.2026.39.3.004.
ABSTRACT
The presence of aortic valve defects in patients is associated with a more severe course of coronary heart disease and heart failure. This article examines the impact of aortic valve defects on the risk of developing and progressing coronary heart disease. The study was conducted based on a retrospective statistical assessment of own clinical experience (a sample of 193 patients in whom the most significant indicators of cardiac function and hemodynamics were determined) and literature data. A significant decrease in the heart's ability to relax and, consequently, greater severity of diastolic dysfunction, manifested by an increase in the size of the left atrium and the diastolic diameter of the LV, were found in patients with aortic valve defects. A relationship between aortic valve defects and the presence of multivessel atherosclerotic lesions was established. For all parameters, p<0,05. The presence of aortic valve defects negatively impacts the course of coronary artery disease, leading to disruption of myocardial structure and function. This fact must be taken into account when assessing the severity of the disease, choosing treatment strategies, and determining the patient's prognosis.
PMID:42502929 | DOI:10.34922/AE.2026.39.3.004